int-snw-84148

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.072	3.62e-18	2.10e-05	3.67e-04

chia-screen-data-Fav-int-snw-84148 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
[ KAT8 ]	84148	2	-1.931	3.072	29	-	-
TPR	7175	18	-2.638	3.072	28	Yes	Yes
MCRS1	10445	14	-2.660	3.079	63	Yes	Yes
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NFRKB	4798	MCRS1	10445	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
TPR	7175	KAT8	84148	pp	--	int.I2D: BioGrid
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
MCRS1	10445	KAT8	84148	pp	--	int.I2D: BioGrid
HCFC1	3054	KAT8	84148	pp	--	int.I2D: BioGrid

Related GO terms (136)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	3.36e-09	4.84e-05	9.646	3	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	3.36e-09	4.84e-05	9.646	3	5	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	3.36e-09	4.84e-05	9.646	3	5	9
GO:0043981	histone H4-K5 acetylation	1.82e-08	2.62e-04	8.909	3	5	15
GO:0043982	histone H4-K8 acetylation	1.82e-08	2.62e-04	8.909	3	5	15
GO:0043984	histone H4-K16 acetylation	3.87e-08	5.58e-04	8.568	3	5	19
GO:0000123	histone acetyltransferase complex	5.31e-08	7.65e-04	8.424	3	6	21
GO:0071339	MLL1 complex	1.17e-07	1.68e-03	8.061	3	6	27
GO:0006325	chromatin organization	1.05e-05	1.51e-01	5.933	3	12	118
GO:0031011	Ino80 complex	1.31e-05	1.89e-01	8.424	2	6	14
GO:0005654	nucleoplasm	1.33e-05	1.91e-01	3.474	5	64	1082
GO:0000776	kinetochore	2.79e-04	1.00e+00	6.254	2	5	63
GO:0006310	DNA recombination	2.97e-04	1.00e+00	6.209	2	7	65
GO:0006355	regulation of transcription, DNA-templated	3.04e-04	1.00e+00	3.270	4	43	997
GO:0060795	cell fate commitment involved in formation of primary germ layer	4.16e-04	1.00e+00	11.231	1	1	1
GO:1901673	regulation of spindle assembly involved in mitosis	4.16e-04	1.00e+00	11.231	1	1	1
GO:0043578	nuclear matrix organization	4.16e-04	1.00e+00	11.231	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	4.16e-04	1.00e+00	11.231	1	1	1
GO:0006404	RNA import into nucleus	4.16e-04	1.00e+00	11.231	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	4.16e-04	1.00e+00	11.231	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	4.16e-04	1.00e+00	11.231	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	4.16e-04	1.00e+00	11.231	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	4.16e-04	1.00e+00	11.231	1	1	1
GO:0006366	transcription from RNA polymerase II promoter	4.56e-04	1.00e+00	4.105	3	30	419
GO:0000189	MAPK import into nucleus	8.32e-04	1.00e+00	10.231	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	8.32e-04	1.00e+00	10.231	1	2	2
GO:0019046	release from viral latency	8.32e-04	1.00e+00	10.231	1	2	2
GO:0009786	regulation of asymmetric cell division	8.32e-04	1.00e+00	10.231	1	1	2
GO:0070840	dynein complex binding	8.32e-04	1.00e+00	10.231	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	8.32e-04	1.00e+00	10.231	1	1	2
GO:0005634	nucleus	9.95e-04	1.00e+00	1.662	6	159	4559
GO:0006405	RNA export from nucleus	1.25e-03	1.00e+00	9.646	1	2	3
GO:0042306	regulation of protein import into nucleus	1.25e-03	1.00e+00	9.646	1	2	3
GO:0060913	cardiac cell fate determination	1.25e-03	1.00e+00	9.646	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.25e-03	1.00e+00	9.646	1	1	3
GO:0072487	MSL complex	1.66e-03	1.00e+00	9.231	1	1	4
GO:0006999	nuclear pore organization	1.66e-03	1.00e+00	9.231	1	1	4
GO:0044615	nuclear pore nuclear basket	1.66e-03	1.00e+00	9.231	1	1	4
GO:0031965	nuclear membrane	1.96e-03	1.00e+00	4.839	2	10	168
GO:0070461	SAGA-type complex	2.08e-03	1.00e+00	8.909	1	2	5
GO:0001714	endodermal cell fate specification	2.08e-03	1.00e+00	8.909	1	1	5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	2.08e-03	1.00e+00	8.909	1	1	5
GO:0010793	regulation of mRNA export from nucleus	2.08e-03	1.00e+00	8.909	1	1	5
GO:0070849	response to epidermal growth factor	2.08e-03	1.00e+00	8.909	1	1	5
GO:0046825	regulation of protein export from nucleus	2.91e-03	1.00e+00	8.424	1	2	7
GO:0051292	nuclear pore complex assembly	3.32e-03	1.00e+00	8.231	1	4	8
GO:0070688	MLL5-L complex	3.32e-03	1.00e+00	8.231	1	1	8
GO:0043254	regulation of protein complex assembly	3.32e-03	1.00e+00	8.231	1	1	8
GO:0035457	cellular response to interferon-alpha	3.32e-03	1.00e+00	8.231	1	1	8
GO:0042405	nuclear inclusion body	3.74e-03	1.00e+00	8.061	1	2	9
GO:0048188	Set1C/COMPASS complex	3.74e-03	1.00e+00	8.061	1	4	9
GO:0043495	protein anchor	3.74e-03	1.00e+00	8.061	1	1	9
GO:0008134	transcription factor binding	4.02e-03	1.00e+00	4.312	2	18	242
GO:0035413	positive regulation of catenin import into nucleus	4.15e-03	1.00e+00	7.909	1	2	10
GO:0016407	acetyltransferase activity	4.15e-03	1.00e+00	7.909	1	2	10
GO:0060391	positive regulation of SMAD protein import into nucleus	4.57e-03	1.00e+00	7.772	1	4	11
GO:0006281	DNA repair	4.66e-03	1.00e+00	4.203	2	14	261
GO:0045947	negative regulation of translational initiation	4.98e-03	1.00e+00	7.646	1	2	12
GO:0034399	nuclear periphery	4.98e-03	1.00e+00	7.646	1	5	12
GO:0035198	miRNA binding	4.98e-03	1.00e+00	7.646	1	1	12
GO:0005515	protein binding	5.30e-03	1.00e+00	1.260	6	198	6024
GO:0042789	mRNA transcription from RNA polymerase II promoter	5.40e-03	1.00e+00	7.531	1	2	13
GO:0051019	mitogen-activated protein kinase binding	5.40e-03	1.00e+00	7.531	1	2	13
GO:0005868	cytoplasmic dynein complex	5.40e-03	1.00e+00	7.531	1	1	13
GO:0046827	positive regulation of protein export from nucleus	5.40e-03	1.00e+00	7.531	1	1	13
GO:0005487	nucleocytoplasmic transporter activity	5.81e-03	1.00e+00	7.424	1	3	14
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	6.22e-03	1.00e+00	7.324	1	3	15
GO:0042307	positive regulation of protein import into nucleus	6.22e-03	1.00e+00	7.324	1	4	15
GO:0001824	blastocyst development	6.22e-03	1.00e+00	7.324	1	2	15
GO:0090316	positive regulation of intracellular protein transport	7.05e-03	1.00e+00	7.144	1	2	17
GO:0003682	chromatin binding	7.24e-03	1.00e+00	3.878	2	19	327
GO:0030099	myeloid cell differentiation	8.29e-03	1.00e+00	6.909	1	2	20
GO:0045787	positive regulation of cell cycle	9.12e-03	1.00e+00	6.772	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	9.12e-03	1.00e+00	6.772	1	4	22
GO:0010506	regulation of autophagy	9.53e-03	1.00e+00	6.708	1	2	23
GO:0016573	histone acetylation	9.53e-03	1.00e+00	6.708	1	2	23
GO:0006611	protein export from nucleus	1.04e-02	1.00e+00	6.587	1	3	25
GO:0015631	tubulin binding	1.12e-02	1.00e+00	6.476	1	2	27
GO:0034605	cellular response to heat	1.16e-02	1.00e+00	6.424	1	1	28
GO:0072686	mitotic spindle	1.20e-02	1.00e+00	6.373	1	3	29
GO:0006606	protein import into nucleus	1.24e-02	1.00e+00	6.324	1	2	30
GO:0031647	regulation of protein stability	1.24e-02	1.00e+00	6.324	1	4	30
GO:0010827	regulation of glucose transport	1.24e-02	1.00e+00	6.324	1	4	30
GO:0007094	mitotic spindle assembly checkpoint	1.28e-02	1.00e+00	6.277	1	3	31
GO:0031072	heat shock protein binding	1.37e-02	1.00e+00	6.187	1	2	33
GO:0007077	mitotic nuclear envelope disassembly	1.49e-02	1.00e+00	6.061	1	4	36
GO:0008645	hexose transport	1.61e-02	1.00e+00	5.946	1	4	39
GO:0035019	somatic stem cell maintenance	1.65e-02	1.00e+00	5.909	1	6	40
GO:0019898	extrinsic component of membrane	1.73e-02	1.00e+00	5.839	1	2	42
GO:0004402	histone acetyltransferase activity	1.78e-02	1.00e+00	5.805	1	6	43
GO:0035064	methylated histone binding	1.90e-02	1.00e+00	5.708	1	2	46
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.10e-02	1.00e+00	3.076	2	37	570
GO:0009611	response to wounding	2.14e-02	1.00e+00	5.531	1	5	52
GO:0005730	nucleolus	2.26e-02	1.00e+00	2.136	3	66	1641
GO:0015758	glucose transport	2.27e-02	1.00e+00	5.450	1	4	55
GO:0005643	nuclear pore	2.35e-02	1.00e+00	5.398	1	11	57
GO:0010468	regulation of gene expression	2.80e-02	1.00e+00	5.144	1	2	68
GO:0003729	mRNA binding	2.96e-02	1.00e+00	5.061	1	4	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	3.04e-02	1.00e+00	5.022	1	4	74
GO:0002020	protease binding	3.04e-02	1.00e+00	5.022	1	6	74
GO:0003700	sequence-specific DNA binding transcription factor activity	3.09e-02	1.00e+00	2.782	2	39	699
GO:0009653	anatomical structure morphogenesis	3.40e-02	1.00e+00	4.856	1	2	83
GO:0006464	cellular protein modification process	3.44e-02	1.00e+00	4.839	1	4	84
GO:0050821	protein stabilization	3.61e-02	1.00e+00	4.772	1	3	88
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.87e-02	1.00e+00	2.607	2	41	789
GO:0005737	cytoplasm	4.38e-02	1.00e+00	1.352	4	124	3767
GO:0005635	nuclear envelope	4.61e-02	1.00e+00	4.411	1	5	113
GO:0005215	transporter activity	5.29e-02	1.00e+00	4.209	1	3	130
GO:0010628	positive regulation of gene expression	5.92e-02	1.00e+00	4.041	1	7	146
GO:0044822	poly(A) RNA binding	6.59e-02	1.00e+00	2.187	2	50	1056
GO:0044212	transcription regulatory region DNA binding	6.79e-02	1.00e+00	3.839	1	17	168
GO:0007049	cell cycle	7.02e-02	1.00e+00	3.788	1	6	174
GO:0005667	transcription factor complex	7.06e-02	1.00e+00	3.780	1	17	175
GO:0031625	ubiquitin protein ligase binding	7.18e-02	1.00e+00	3.755	1	5	178
GO:0003677	DNA binding	8.50e-02	1.00e+00	1.981	2	49	1218
GO:0019221	cytokine-mediated signaling pathway	8.85e-02	1.00e+00	3.443	1	8	221
GO:0007067	mitotic nuclear division	9.08e-02	1.00e+00	3.405	1	6	227
GO:0003713	transcription coactivator activity	9.46e-02	1.00e+00	3.342	1	24	237
GO:0043025	neuronal cell body	9.77e-02	1.00e+00	3.294	1	9	245
GO:0005975	carbohydrate metabolic process	1.01e-01	1.00e+00	3.248	1	8	253
GO:0006954	inflammatory response	1.10e-01	1.00e+00	3.117	1	6	277
GO:0019899	enzyme binding	1.10e-01	1.00e+00	3.117	1	9	277
GO:0006351	transcription, DNA-templated	1.15e-01	1.00e+00	1.733	2	57	1446
GO:0043565	sequence-specific DNA binding	1.36e-01	1.00e+00	2.796	1	11	346
GO:0000278	mitotic cell cycle	1.52e-01	1.00e+00	2.620	1	15	391
GO:0045892	negative regulation of transcription, DNA-templated	1.60e-01	1.00e+00	2.541	1	24	413
GO:0055085	transmembrane transport	1.68e-01	1.00e+00	2.466	1	8	435
GO:0045893	positive regulation of transcription, DNA-templated	1.83e-01	1.00e+00	2.330	1	24	478
GO:0042802	identical protein binding	1.85e-01	1.00e+00	2.312	1	19	484
GO:0016032	viral process	2.03e-01	1.00e+00	2.170	1	26	534
GO:0042803	protein homodimerization activity	2.23e-01	1.00e+00	2.014	1	19	595
GO:0005739	mitochondrion	3.50e-01	1.00e+00	1.268	1	23	998
GO:0044281	small molecule metabolic process	4.09e-01	1.00e+00	0.989	1	20	1211
GO:0046872	metal ion binding	4.35e-01	1.00e+00	0.879	1	29	1307
GO:0016020	membrane	5.25e-01	1.00e+00	0.516	1	46	1681
GO:0005829	cytosol	6.80e-01	1.00e+00	-0.054	1	86	2496

chia-Fav

int-snw-84148

Statistics

Genes (6)

Interactions (6)

Related GO terms (136)