int-snw-7812

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.847	1.22e-15	4.17e-04	3.05e-03

chia-screen-data-Fav-int-snw-7812 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
[ CSDE1 ]	7812	1	-1.711	2.847	21	-	-
CDC42	998	9	-2.199	3.119	265	Yes	Yes
SYNCRIP	10492	9	-2.401	3.197	103	Yes	Yes
TBC1D10A	83874	8	-2.544	2.989	26	Yes	-
SHFM1	7979	2	-2.366	2.847	6	Yes	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
HNRNPD	3184	5	-2.153	3.117	123	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes

Interactions (12)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPD	3184	HNRNPU	3192	pp	--	int.Mint: MI:0915(physical association)
CSDE1	7812	SYNCRIP	10492	pp	--	int.I2D: HPRD; int.HPRD: in vivo
DDIT3	1649	HNRNPD	3184	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
CDC42	998	SHFM1	7979	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
CDC42	998	TBC1D10A	83874	pp	--	int.I2D: BioGrid_Yeast
HNRNPU	3192	SYNCRIP	10492	pp	--	int.Mint: MI:0915(physical association)
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
CDC42	998	CSDE1	7812	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
HNRNPD	3184	SYNCRIP	10492	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
HNRNPD	3184	CSDE1	7812	pp	--	int.I2D: HPRD; int.Ravasi: -; int.HPRD: in vivo

Related GO terms (201)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0070937	CRD-mediated mRNA stability complex	4.80e-09	6.92e-05	9.494	3	3	6
GO:0070934	CRD-mediated mRNA stabilization	4.32e-06	6.23e-02	9.172	2	2	5
GO:0006396	RNA processing	7.65e-06	1.10e-01	6.196	3	5	59
GO:0005654	nucleoplasm	2.84e-05	4.09e-01	3.000	6	64	1082
GO:0042789	mRNA transcription from RNA polymerase II promoter	3.36e-05	4.85e-01	7.794	2	2	13
GO:0030529	ribonucleoprotein complex	5.26e-05	7.58e-01	5.272	3	5	112
GO:0036464	cytoplasmic ribonucleoprotein granule	9.92e-05	1.00e+00	7.035	2	2	22
GO:0000398	mRNA splicing, via spliceosome	1.63e-04	1.00e+00	4.722	3	15	164
GO:0044212	transcription regulatory region DNA binding	1.75e-04	1.00e+00	4.687	3	17	168
GO:0006355	regulation of transcription, DNA-templated	2.94e-04	1.00e+00	2.855	5	43	997
GO:0044822	poly(A) RNA binding	3.85e-04	1.00e+00	2.772	5	50	1056
GO:0008380	RNA splicing	4.31e-04	1.00e+00	4.246	3	22	228
GO:0043525	positive regulation of neuron apoptotic process	4.41e-04	1.00e+00	5.971	2	4	46
GO:0060795	cell fate commitment involved in formation of primary germ layer	6.93e-04	1.00e+00	10.494	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	6.93e-04	1.00e+00	10.494	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	6.93e-04	1.00e+00	10.494	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	6.93e-04	1.00e+00	10.494	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	6.93e-04	1.00e+00	10.494	1	1	1
GO:0071013	catalytic step 2 spliceosome	1.26e-03	1.00e+00	5.209	2	7	78
GO:0071338	positive regulation of hair follicle cell proliferation	1.39e-03	1.00e+00	9.494	1	1	2
GO:0060242	contact inhibition	1.39e-03	1.00e+00	9.494	1	1	2
GO:0090135	actin filament branching	1.39e-03	1.00e+00	9.494	1	1	2
GO:0009786	regulation of asymmetric cell division	1.39e-03	1.00e+00	9.494	1	1	2
GO:0060661	submandibular salivary gland formation	1.39e-03	1.00e+00	9.494	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	1.39e-03	1.00e+00	9.494	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	1.39e-03	1.00e+00	9.494	1	1	2
GO:0003723	RNA binding	1.40e-03	1.00e+00	3.661	3	18	342
GO:0001649	osteoblast differentiation	1.75e-03	1.00e+00	4.971	2	5	92
GO:0051683	establishment of Golgi localization	2.08e-03	1.00e+00	8.909	1	1	3
GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay	2.08e-03	1.00e+00	8.909	1	1	3
GO:0034191	apolipoprotein A-I receptor binding	2.08e-03	1.00e+00	8.909	1	1	3
GO:0060913	cardiac cell fate determination	2.08e-03	1.00e+00	8.909	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	2.08e-03	1.00e+00	8.909	1	1	3
GO:0003161	cardiac conduction system development	2.08e-03	1.00e+00	8.909	1	1	3
GO:0005515	protein binding	2.41e-03	1.00e+00	1.108	9	198	6024
GO:0097167	circadian regulation of translation	2.77e-03	1.00e+00	8.494	1	1	4
GO:0097452	GAIT complex	2.77e-03	1.00e+00	8.494	1	1	4
GO:0060684	epithelial-mesenchymal cell signaling	2.77e-03	1.00e+00	8.494	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	2.77e-03	1.00e+00	8.494	1	1	4
GO:0048664	neuron fate determination	2.77e-03	1.00e+00	8.494	1	1	4
GO:0072384	organelle transport along microtubule	2.77e-03	1.00e+00	8.494	1	1	4
GO:0001714	endodermal cell fate specification	3.46e-03	1.00e+00	8.172	1	1	5
GO:0035088	establishment or maintenance of apical/basal cell polarity	3.46e-03	1.00e+00	8.172	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	3.46e-03	1.00e+00	8.172	1	1	5
GO:0036336	dendritic cell migration	3.46e-03	1.00e+00	8.172	1	1	5
GO:0031256	leading edge membrane	3.46e-03	1.00e+00	8.172	1	1	5
GO:0060789	hair follicle placode formation	4.15e-03	1.00e+00	7.909	1	2	6
GO:0007097	nuclear migration	4.15e-03	1.00e+00	7.909	1	1	6
GO:0003334	keratinocyte development	4.15e-03	1.00e+00	7.909	1	1	6
GO:0071204	histone pre-mRNA 3'end processing complex	4.15e-03	1.00e+00	7.909	1	1	6
GO:0048554	positive regulation of metalloenzyme activity	4.15e-03	1.00e+00	7.909	1	1	6
GO:0043497	regulation of protein heterodimerization activity	4.15e-03	1.00e+00	7.909	1	1	6
GO:0006974	cellular response to DNA damage stimulus	4.64e-03	1.00e+00	4.256	2	7	151
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	4.84e-03	1.00e+00	7.687	1	2	7
GO:0051489	regulation of filopodium assembly	4.84e-03	1.00e+00	7.687	1	1	7
GO:0097202	activation of cysteine-type endopeptidase activity	5.53e-03	1.00e+00	7.494	1	1	8
GO:0001955	blood vessel maturation	5.53e-03	1.00e+00	7.494	1	1	8
GO:0090136	epithelial cell-cell adhesion	6.22e-03	1.00e+00	7.324	1	1	9
GO:0006983	ER overload response	6.22e-03	1.00e+00	7.324	1	1	9
GO:0003714	transcription corepressor activity	6.39e-03	1.00e+00	4.018	2	11	178
GO:0035413	positive regulation of catenin import into nucleus	6.91e-03	1.00e+00	7.172	1	2	10
GO:0031274	positive regulation of pseudopodium assembly	6.91e-03	1.00e+00	7.172	1	2	10
GO:0060047	heart contraction	6.91e-03	1.00e+00	7.172	1	1	10
GO:0003677	DNA binding	7.02e-03	1.00e+00	2.244	4	49	1218
GO:0042162	telomeric DNA binding	7.60e-03	1.00e+00	7.035	1	1	11
GO:0045662	negative regulation of myoblast differentiation	7.60e-03	1.00e+00	7.035	1	3	11
GO:0060391	positive regulation of SMAD protein import into nucleus	7.60e-03	1.00e+00	7.035	1	4	11
GO:0008143	poly(A) binding	8.29e-03	1.00e+00	6.909	1	2	12
GO:0035198	miRNA binding	8.29e-03	1.00e+00	6.909	1	1	12
GO:0071480	cellular response to gamma radiation	8.98e-03	1.00e+00	6.794	1	1	13
GO:0032039	integrator complex	8.98e-03	1.00e+00	6.794	1	1	13
GO:0043488	regulation of mRNA stability	8.98e-03	1.00e+00	6.794	1	1	13
GO:0010467	gene expression	9.33e-03	1.00e+00	2.693	3	45	669
GO:0031333	negative regulation of protein complex assembly	9.67e-03	1.00e+00	6.687	1	1	14
GO:0031996	thioesterase binding	9.67e-03	1.00e+00	6.687	1	1	14
GO:0006401	RNA catabolic process	9.67e-03	1.00e+00	6.687	1	1	14
GO:0001824	blastocyst development	1.04e-02	1.00e+00	6.587	1	2	15
GO:0051233	spindle midzone	1.04e-02	1.00e+00	6.587	1	2	15
GO:0030225	macrophage differentiation	1.04e-02	1.00e+00	6.587	1	2	15
GO:0042176	regulation of protein catabolic process	1.10e-02	1.00e+00	6.494	1	2	16
GO:0008134	transcription factor binding	1.15e-02	1.00e+00	3.575	2	18	242
GO:0030742	GTP-dependent protein binding	1.17e-02	1.00e+00	6.407	1	1	17
GO:0090316	positive regulation of intracellular protein transport	1.17e-02	1.00e+00	6.407	1	2	17
GO:0007088	regulation of mitosis	1.24e-02	1.00e+00	6.324	1	1	18
GO:0046847	filopodium assembly	1.31e-02	1.00e+00	6.246	1	1	19
GO:0000166	nucleotide binding	1.31e-02	1.00e+00	3.477	2	13	259
GO:0032757	positive regulation of interleukin-8 production	1.38e-02	1.00e+00	6.172	1	1	20
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1.45e-02	1.00e+00	6.102	1	1	21
GO:0045862	positive regulation of proteolysis	1.45e-02	1.00e+00	6.102	1	2	21
GO:0031424	keratinization	1.52e-02	1.00e+00	6.035	1	1	22
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	1.58e-02	1.00e+00	5.971	1	3	23
GO:0071346	cellular response to interferon-gamma	1.58e-02	1.00e+00	5.971	1	1	23
GO:0002040	sprouting angiogenesis	1.58e-02	1.00e+00	5.971	1	2	23
GO:0051017	actin filament bundle assembly	1.58e-02	1.00e+00	5.971	1	1	23
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	1.58e-02	1.00e+00	5.971	1	1	23
GO:0007163	establishment or maintenance of cell polarity	1.65e-02	1.00e+00	5.909	1	2	24
GO:1902017	regulation of cilium assembly	1.65e-02	1.00e+00	5.909	1	2	24
GO:0035329	hippo signaling	1.79e-02	1.00e+00	5.794	1	5	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.79e-02	1.00e+00	5.794	1	3	26
GO:0051209	release of sequestered calcium ion into cytosol	1.79e-02	1.00e+00	5.794	1	1	26
GO:0045859	regulation of protein kinase activity	1.79e-02	1.00e+00	5.794	1	1	26
GO:0005829	cytosol	1.81e-02	1.00e+00	1.531	5	86	2496
GO:0051149	positive regulation of muscle cell differentiation	1.86e-02	1.00e+00	5.739	1	4	27
GO:0032467	positive regulation of cytokinesis	1.86e-02	1.00e+00	5.739	1	2	27
GO:0031069	hair follicle morphogenesis	1.86e-02	1.00e+00	5.739	1	1	27
GO:0072686	mitotic spindle	1.99e-02	1.00e+00	5.636	1	3	29
GO:0031647	regulation of protein stability	2.06e-02	1.00e+00	5.587	1	4	30
GO:0042594	response to starvation	2.13e-02	1.00e+00	5.540	1	4	31
GO:1903507	negative regulation of nucleic acid-templated transcription	2.20e-02	1.00e+00	5.494	1	2	32
GO:0043565	sequence-specific DNA binding	2.27e-02	1.00e+00	3.060	2	11	346
GO:0005097	Rab GTPase activator activity	2.33e-02	1.00e+00	5.407	1	1	34
GO:0042692	muscle cell differentiation	2.33e-02	1.00e+00	5.407	1	4	34
GO:0034332	adherens junction organization	2.47e-02	1.00e+00	5.324	1	2	36
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	2.47e-02	1.00e+00	5.324	1	2	36
GO:0045740	positive regulation of DNA replication	2.47e-02	1.00e+00	5.324	1	1	36
GO:0042752	regulation of circadian rhythm	2.54e-02	1.00e+00	5.285	1	3	37
GO:0005902	microvillus	2.60e-02	1.00e+00	5.246	1	3	38
GO:0035019	somatic stem cell maintenance	2.74e-02	1.00e+00	5.172	1	6	40
GO:0017148	negative regulation of translation	2.74e-02	1.00e+00	5.172	1	2	40
GO:0042147	retrograde transport, endosome to Golgi	2.81e-02	1.00e+00	5.137	1	1	41
GO:0021762	substantia nigra development	3.01e-02	1.00e+00	5.035	1	4	44
GO:0034613	cellular protein localization	3.01e-02	1.00e+00	5.035	1	2	44
GO:0045727	positive regulation of translation	3.01e-02	1.00e+00	5.035	1	2	44
GO:0007030	Golgi organization	3.35e-02	1.00e+00	4.879	1	3	49
GO:0030175	filopodium	3.41e-02	1.00e+00	4.850	1	1	50
GO:0006986	response to unfolded protein	3.41e-02	1.00e+00	4.850	1	4	50
GO:0034976	response to endoplasmic reticulum stress	3.48e-02	1.00e+00	4.822	1	2	51
GO:0045454	cell redox homeostasis	3.48e-02	1.00e+00	4.822	1	1	51
GO:0009611	response to wounding	3.55e-02	1.00e+00	4.794	1	5	52
GO:0032851	positive regulation of Rab GTPase activity	3.62e-02	1.00e+00	4.766	1	2	53
GO:0046330	positive regulation of JNK cascade	3.75e-02	1.00e+00	4.713	1	2	55
GO:0000724	double-strand break repair via homologous recombination	3.75e-02	1.00e+00	4.713	1	2	55
GO:0000502	proteasome complex	3.95e-02	1.00e+00	4.636	1	3	58
GO:0033138	positive regulation of peptidyl-serine phosphorylation	4.02e-02	1.00e+00	4.612	1	2	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	4.02e-02	1.00e+00	4.612	1	6	59
GO:0045893	positive regulation of transcription, DNA-templated	4.14e-02	1.00e+00	2.593	2	24	478
GO:0006987	activation of signaling protein activity involved in unfolded protein response	4.15e-02	1.00e+00	4.563	1	2	61
GO:0030141	secretory granule	4.22e-02	1.00e+00	4.540	1	4	62
GO:0031295	T cell costimulation	4.42e-02	1.00e+00	4.472	1	1	65
GO:0035264	multicellular organism growth	4.55e-02	1.00e+00	4.428	1	2	67
GO:0010468	regulation of gene expression	4.62e-02	1.00e+00	4.407	1	2	68
GO:0005085	guanyl-nucleotide exchange factor activity	4.82e-02	1.00e+00	4.344	1	5	71
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	5.02e-02	1.00e+00	4.285	1	2	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	5.02e-02	1.00e+00	4.285	1	4	74
GO:0008584	male gonad development	5.08e-02	1.00e+00	4.265	1	3	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	5.08e-02	1.00e+00	4.265	1	1	75
GO:0060070	canonical Wnt signaling pathway	5.08e-02	1.00e+00	4.265	1	4	75
GO:0010629	negative regulation of gene expression	5.21e-02	1.00e+00	4.227	1	4	77
GO:0030968	endoplasmic reticulum unfolded protein response	5.35e-02	1.00e+00	4.190	1	2	79
GO:0045177	apical part of cell	5.48e-02	1.00e+00	4.154	1	3	81
GO:0009653	anatomical structure morphogenesis	5.61e-02	1.00e+00	4.119	1	2	83
GO:0090090	negative regulation of canonical Wnt signaling pathway	5.81e-02	1.00e+00	4.068	1	8	86
GO:0005634	nucleus	6.02e-02	1.00e+00	0.925	6	159	4559
GO:0005770	late endosome	6.27e-02	1.00e+00	3.955	1	2	93
GO:0030165	PDZ domain binding	6.33e-02	1.00e+00	3.940	1	1	94
GO:0030496	midbody	7.24e-02	1.00e+00	3.739	1	2	108
GO:0005815	microtubule organizing center	7.31e-02	1.00e+00	3.726	1	3	109
GO:0051056	regulation of small GTPase mediated signal transduction	7.70e-02	1.00e+00	3.649	1	3	115
GO:0003700	sequence-specific DNA binding transcription factor activity	8.15e-02	1.00e+00	2.045	2	39	699
GO:0030036	actin cytoskeleton organization	8.21e-02	1.00e+00	3.552	1	3	123
GO:0007050	cell cycle arrest	8.27e-02	1.00e+00	3.540	1	5	124
GO:0005911	cell-cell junction	9.04e-02	1.00e+00	3.407	1	2	136
GO:0016055	Wnt signaling pathway	9.17e-02	1.00e+00	3.386	1	4	138
GO:0010628	positive regulation of gene expression	9.68e-02	1.00e+00	3.304	1	7	146
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.00e-01	1.00e+00	1.870	2	41	789
GO:0016020	membrane	1.01e-01	1.00e+00	1.364	3	46	1681
GO:0043005	neuron projection	1.04e-01	1.00e+00	3.200	1	3	157
GO:0005667	transcription factor complex	1.15e-01	1.00e+00	3.043	1	17	175
GO:0031625	ubiquitin protein ligase binding	1.17e-01	1.00e+00	3.018	1	5	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.21e-01	1.00e+00	2.971	1	22	184
GO:0007173	epidermal growth factor receptor signaling pathway	1.24e-01	1.00e+00	2.932	1	5	189
GO:0003924	GTPase activity	1.29e-01	1.00e+00	2.872	1	7	197
GO:0006184	GTP catabolic process	1.39e-01	1.00e+00	2.753	1	7	214
GO:0016071	mRNA metabolic process	1.44e-01	1.00e+00	2.693	1	8	223
GO:0003713	transcription coactivator activity	1.53e-01	1.00e+00	2.605	1	24	237
GO:0043025	neuronal cell body	1.57e-01	1.00e+00	2.558	1	9	245
GO:0016070	RNA metabolic process	1.59e-01	1.00e+00	2.546	1	8	247
GO:0007264	small GTPase mediated signal transduction	1.77e-01	1.00e+00	2.370	1	3	279
GO:0005525	GTP binding	1.95e-01	1.00e+00	2.218	1	12	310
GO:0019901	protein kinase binding	1.99e-01	1.00e+00	2.186	1	18	317
GO:0007411	axon guidance	2.00e-01	1.00e+00	2.177	1	5	319
GO:0008283	cell proliferation	2.06e-01	1.00e+00	2.137	1	14	328
GO:0070062	extracellular vesicular exosome	2.24e-01	1.00e+00	0.850	3	57	2400
GO:0000139	Golgi membrane	2.24e-01	1.00e+00	1.998	1	7	361
GO:0005925	focal adhesion	2.27e-01	1.00e+00	1.978	1	9	366
GO:0046982	protein heterodimerization activity	2.34e-01	1.00e+00	1.924	1	8	380
GO:0009986	cell surface	2.46e-01	1.00e+00	1.843	1	9	402
GO:0005737	cytoplasm	2.51e-01	1.00e+00	0.615	4	124	3767
GO:0045892	negative regulation of transcription, DNA-templated	2.52e-01	1.00e+00	1.804	1	24	413
GO:0006366	transcription from RNA polymerase II promoter	2.55e-01	1.00e+00	1.783	1	30	419
GO:0005886	plasma membrane	2.60e-01	1.00e+00	0.745	3	49	2582
GO:0007596	blood coagulation	2.74e-01	1.00e+00	1.664	1	11	455
GO:0044267	cellular protein metabolic process	2.84e-01	1.00e+00	1.605	1	20	474
GO:0042802	identical protein binding	2.89e-01	1.00e+00	1.575	1	19	484
GO:0016032	viral process	3.14e-01	1.00e+00	1.433	1	26	534
GO:0005783	endoplasmic reticulum	3.25e-01	1.00e+00	1.375	1	13	556
GO:0045087	innate immune response	3.44e-01	1.00e+00	1.275	1	15	596
GO:0005794	Golgi apparatus	3.51e-01	1.00e+00	1.241	1	9	610
GO:0005524	ATP binding	6.11e-01	1.00e+00	0.152	1	31	1298
GO:0006351	transcription, DNA-templated	6.52e-01	1.00e+00	-0.004	1	57	1446
GO:0005730	nucleolus	7.01e-01	1.00e+00	-0.186	1	66	1641

chia-Fav

int-snw-7812

Statistics

Genes (10)

Interactions (12)

Related GO terms (201)