int-snw-6733

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.104	1.49e-18	1.30e-05	2.61e-04

chia-screen-data-Fav-int-snw-6733 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
TMED10	10972	3	-1.992	3.104	106	-	-
LUC7L3	51747	33	-3.523	3.449	18	Yes	-
DARS	1615	1	-2.086	3.104	110	Yes	-
[ SRPK2 ]	6733	2	-1.817	3.104	98	-	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
SRPK2	6733	TMED10	10972	pp	--	int.I2D: BioGrid_Yeast
SRPK2	6733	LUC7L3	51747	pp	--	int.I2D: BioGrid
SRSF3	6428	SRPK2	6733	pp	--	int.I2D: BioGrid
DARS	1615	SRPK2	6733	pp	--	int.I2D: BioGrid_Yeast, Yeast_Kinome
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
DARS	1615	PSMD2	5708	pp	--	int.I2D: BioGrid_Yeast
PSMD2	5708	TMED10	10972	pp	--	int.I2D: IntAct_Yeast

Related GO terms (132)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0044822	poly(A) RNA binding	3.86e-05	5.57e-01	3.286	5	50	1056
GO:0008380	RNA splicing	1.30e-04	1.00e+00	4.761	3	22	228
GO:0006422	aspartyl-tRNA aminoacylation	4.85e-04	1.00e+00	11.009	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	4.85e-04	1.00e+00	11.009	1	1	1
GO:0048199	vesicle targeting, to, from or within Golgi	4.85e-04	1.00e+00	11.009	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	4.85e-04	1.00e+00	11.009	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	4.85e-04	1.00e+00	11.009	1	1	1
GO:0035063	nuclear speck organization	4.85e-04	1.00e+00	11.009	1	1	1
GO:1902003	regulation of beta-amyloid formation	4.85e-04	1.00e+00	11.009	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	4.85e-04	1.00e+00	11.009	1	1	1
GO:0035964	COPI-coated vesicle budding	4.85e-04	1.00e+00	11.009	1	1	1
GO:0070765	gamma-secretase complex	9.70e-04	1.00e+00	10.009	1	1	2
GO:0004815	aspartate-tRNA ligase activity	9.70e-04	1.00e+00	10.009	1	1	2
GO:0009786	regulation of asymmetric cell division	9.70e-04	1.00e+00	10.009	1	1	2
GO:0060913	cardiac cell fate determination	1.46e-03	1.00e+00	9.424	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.46e-03	1.00e+00	9.424	1	1	3
GO:0035459	cargo loading into vesicle	1.94e-03	1.00e+00	9.009	1	1	4
GO:0004046	aminoacylase activity	1.94e-03	1.00e+00	9.009	1	1	4
GO:0030137	COPI-coated vesicle	1.94e-03	1.00e+00	9.009	1	1	4
GO:0005515	protein binding	2.21e-03	1.00e+00	1.260	7	198	6024
GO:0001714	endodermal cell fate specification	2.42e-03	1.00e+00	8.687	1	1	5
GO:0043279	response to alkaloid	2.42e-03	1.00e+00	8.687	1	2	5
GO:0016607	nuclear speck	2.85e-03	1.00e+00	4.582	2	12	172
GO:0048024	regulation of mRNA splicing, via spliceosome	2.91e-03	1.00e+00	8.424	1	1	6
GO:0010467	gene expression	3.02e-03	1.00e+00	3.208	3	45	669
GO:0035413	positive regulation of catenin import into nucleus	4.84e-03	1.00e+00	7.687	1	2	10
GO:0042589	zymogen granule membrane	4.84e-03	1.00e+00	7.687	1	1	10
GO:0045055	regulated secretory pathway	4.84e-03	1.00e+00	7.687	1	1	10
GO:0060391	positive regulation of SMAD protein import into nucleus	5.33e-03	1.00e+00	7.549	1	4	11
GO:0030667	secretory granule membrane	5.81e-03	1.00e+00	7.424	1	2	12
GO:0005838	proteasome regulatory particle	5.81e-03	1.00e+00	7.424	1	1	12
GO:0030140	trans-Golgi network transport vesicle	5.81e-03	1.00e+00	7.424	1	1	12
GO:0035198	miRNA binding	5.81e-03	1.00e+00	7.424	1	1	12
GO:0030234	enzyme regulator activity	6.29e-03	1.00e+00	7.308	1	2	13
GO:0048205	COPI coating of Golgi vesicle	6.29e-03	1.00e+00	7.308	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	6.29e-03	1.00e+00	7.308	1	2	13
GO:0005685	U1 snRNP	6.78e-03	1.00e+00	7.201	1	1	14
GO:0048208	COPII vesicle coating	7.26e-03	1.00e+00	7.102	1	1	15
GO:0006376	mRNA splice site selection	7.26e-03	1.00e+00	7.102	1	1	15
GO:0001824	blastocyst development	7.26e-03	1.00e+00	7.102	1	2	15
GO:0043274	phospholipase binding	7.74e-03	1.00e+00	7.009	1	1	16
GO:0042176	regulation of protein catabolic process	7.74e-03	1.00e+00	7.009	1	2	16
GO:0022624	proteasome accessory complex	8.22e-03	1.00e+00	6.921	1	1	17
GO:0045070	positive regulation of viral genome replication	8.22e-03	1.00e+00	6.921	1	1	17
GO:0071889	14-3-3 protein binding	8.71e-03	1.00e+00	6.839	1	2	18
GO:0000245	spliceosomal complex assembly	1.01e-02	1.00e+00	6.616	1	2	21
GO:0045787	positive regulation of cell cycle	1.06e-02	1.00e+00	6.549	1	2	22
GO:0005654	nucleoplasm	1.17e-02	1.00e+00	2.514	3	64	1082
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.21e-02	1.00e+00	6.365	1	1	25
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	1.30e-02	1.00e+00	6.254	1	1	27
GO:0030658	transport vesicle membrane	1.54e-02	1.00e+00	6.009	1	1	32
GO:0005801	cis-Golgi network	1.59e-02	1.00e+00	5.964	1	1	33
GO:0019905	syntaxin binding	1.59e-02	1.00e+00	5.964	1	2	33
GO:0006366	transcription from RNA polymerase II promoter	1.60e-02	1.00e+00	3.298	2	30	419
GO:0045071	negative regulation of viral genome replication	1.64e-02	1.00e+00	5.921	1	1	34
GO:0051259	protein oligomerization	1.88e-02	1.00e+00	5.723	1	2	39
GO:0035019	somatic stem cell maintenance	1.93e-02	1.00e+00	5.687	1	6	40
GO:0006418	tRNA aminoacylation for protein translation	2.02e-02	1.00e+00	5.616	1	3	42
GO:0031124	mRNA 3'-end processing	2.02e-02	1.00e+00	5.616	1	2	42
GO:0006369	termination of RNA polymerase II transcription	2.16e-02	1.00e+00	5.517	1	2	45
GO:0043525	positive regulation of neuron apoptotic process	2.21e-02	1.00e+00	5.485	1	4	46
GO:0007030	Golgi organization	2.35e-02	1.00e+00	5.394	1	3	49
GO:0006521	regulation of cellular amino acid metabolic process	2.40e-02	1.00e+00	5.365	1	1	50
GO:0009611	response to wounding	2.50e-02	1.00e+00	5.308	1	5	52
GO:0006888	ER to Golgi vesicle-mediated transport	2.54e-02	1.00e+00	5.281	1	1	53
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	2.69e-02	1.00e+00	5.201	1	2	56
GO:0000502	proteasome complex	2.78e-02	1.00e+00	5.151	1	3	58
GO:0006406	mRNA export from nucleus	2.92e-02	1.00e+00	5.078	1	4	61
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.07e-02	1.00e+00	5.009	1	1	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.11e-02	1.00e+00	4.986	1	2	65
GO:0010468	regulation of gene expression	3.25e-02	1.00e+00	4.921	1	2	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.35e-02	1.00e+00	4.879	1	2	70
GO:0003729	mRNA binding	3.44e-02	1.00e+00	4.839	1	4	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.44e-02	1.00e+00	4.839	1	1	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	3.54e-02	1.00e+00	4.799	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.54e-02	1.00e+00	4.799	1	2	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.58e-02	1.00e+00	4.780	1	1	75
GO:0001822	kidney development	3.73e-02	1.00e+00	4.723	1	3	78
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.77e-02	1.00e+00	4.705	1	2	79
GO:0009653	anatomical structure morphogenesis	3.96e-02	1.00e+00	4.634	1	2	83
GO:0042470	melanosome	4.33e-02	1.00e+00	4.501	1	2	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.38e-02	1.00e+00	4.485	1	1	92
GO:0006461	protein complex assembly	5.27e-02	1.00e+00	4.214	1	4	111
GO:0000209	protein polyubiquitination	5.50e-02	1.00e+00	4.151	1	3	116
GO:0010628	positive regulation of gene expression	6.88e-02	1.00e+00	3.819	1	7	146
GO:0000082	G1/S transition of mitotic cell cycle	7.01e-02	1.00e+00	3.790	1	3	149
GO:0042981	regulation of apoptotic process	7.06e-02	1.00e+00	3.780	1	4	150
GO:0000287	magnesium ion binding	7.69e-02	1.00e+00	3.651	1	4	164
GO:0000398	mRNA splicing, via spliceosome	7.69e-02	1.00e+00	3.651	1	15	164
GO:0044212	transcription regulatory region DNA binding	7.88e-02	1.00e+00	3.616	1	17	168
GO:0006886	intracellular protein transport	8.01e-02	1.00e+00	3.591	1	4	171
GO:0034641	cellular nitrogen compound metabolic process	8.01e-02	1.00e+00	3.591	1	2	171
GO:0005737	cytoplasm	8.13e-02	1.00e+00	1.130	4	124	3767
GO:0005667	transcription factor complex	8.19e-02	1.00e+00	3.558	1	17	175
GO:0031625	ubiquitin protein ligase binding	8.33e-02	1.00e+00	3.533	1	5	178
GO:0032403	protein complex binding	8.55e-02	1.00e+00	3.493	1	6	183
GO:0001525	angiogenesis	8.91e-02	1.00e+00	3.431	1	7	191
GO:0070062	extracellular vesicular exosome	9.54e-02	1.00e+00	1.365	3	57	2400
GO:0016071	mRNA metabolic process	1.03e-01	1.00e+00	3.208	1	8	223
GO:0005829	cytosol	1.05e-01	1.00e+00	1.308	3	86	2496
GO:0006412	translation	1.06e-01	1.00e+00	3.163	1	8	230
GO:0008134	transcription factor binding	1.12e-01	1.00e+00	3.090	1	18	242
GO:0003677	DNA binding	1.13e-01	1.00e+00	1.758	2	49	1218
GO:0016070	RNA metabolic process	1.14e-01	1.00e+00	3.060	1	8	247
GO:0000166	nucleotide binding	1.19e-01	1.00e+00	2.992	1	13	259
GO:0005524	ATP binding	1.25e-01	1.00e+00	1.667	2	31	1298
GO:0030154	cell differentiation	1.37e-01	1.00e+00	2.775	1	5	301
GO:0035556	intracellular signal transduction	1.38e-01	1.00e+00	2.766	1	9	303
GO:0004674	protein serine/threonine kinase activity	1.40e-01	1.00e+00	2.742	1	6	308
GO:0003723	RNA binding	1.55e-01	1.00e+00	2.591	1	18	342
GO:0043565	sequence-specific DNA binding	1.56e-01	1.00e+00	2.574	1	11	346
GO:0000139	Golgi membrane	1.63e-01	1.00e+00	2.513	1	7	361
GO:0005925	focal adhesion	1.65e-01	1.00e+00	2.493	1	9	366
GO:0008284	positive regulation of cell proliferation	1.71e-01	1.00e+00	2.431	1	10	382
GO:0000278	mitotic cell cycle	1.75e-01	1.00e+00	2.398	1	15	391
GO:0005730	nucleolus	1.85e-01	1.00e+00	1.328	2	66	1641
GO:0043066	negative regulation of apoptotic process	1.89e-01	1.00e+00	2.281	1	16	424
GO:0016020	membrane	1.92e-01	1.00e+00	1.294	2	46	1681
GO:0006468	protein phosphorylation	2.03e-01	1.00e+00	2.163	1	10	460
GO:0016032	viral process	2.32e-01	1.00e+00	1.948	1	26	534
GO:0006915	apoptotic process	2.40e-01	1.00e+00	1.892	1	12	555
GO:0005783	endoplasmic reticulum	2.41e-01	1.00e+00	1.890	1	13	556
GO:0005789	endoplasmic reticulum membrane	2.46e-01	1.00e+00	1.854	1	9	570
GO:0045087	innate immune response	2.56e-01	1.00e+00	1.790	1	15	596
GO:0005794	Golgi apparatus	2.61e-01	1.00e+00	1.756	1	9	610
GO:0003700	sequence-specific DNA binding transcription factor activity	2.94e-01	1.00e+00	1.560	1	39	699
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.26e-01	1.00e+00	1.385	1	41	789
GO:0005886	plasma membrane	3.65e-01	1.00e+00	0.674	2	49	2582
GO:0005634	nucleus	3.90e-01	1.00e+00	0.439	3	159	4559
GO:0006355	regulation of transcription, DNA-templated	3.94e-01	1.00e+00	1.047	1	43	997
GO:0044281	small molecule metabolic process	4.59e-01	1.00e+00	0.767	1	20	1211
GO:0016021	integral component of membrane	6.45e-01	1.00e+00	0.056	1	17	1982

chia-Fav

int-snw-6733

Statistics

Genes (7)

Interactions (7)

Related GO terms (132)