meta-int-snw-5700

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-4522	wolf-screen-ratio-mammosphere-adherent	0.815	1.50e-06	3.75e-03	6.95e-03	14	12
int-snw-5700	wolf-screen-ratio-mammosphere-adherent	1.018	6.82e-19	3.53e-04	9.29e-03	8	8
reg-snw-56655	wolf-screen-ratio-mammosphere-adherent	0.828	9.29e-07	2.91e-03	5.53e-03	8	7
reg-snw-317781	wolf-screen-ratio-mammosphere-adherent	0.823	1.13e-06	3.23e-03	6.07e-03	9	9

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-5700 subnetwork

Genes (24)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA2	5683	112	1.093	1.106	108	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
POLR2F	5435	62	0.891	0.956	26	Yes	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
HNRNPC	3183	108	1.812	0.973	181	Yes	-
PSMA1	5682	100	0.996	0.878	152	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
DDX51	317781	53	0.059	0.823	210	Yes	-
POLE4	56655	63	0.177	0.828	56	-	-
PSMB3	5691	64	0.668	0.901	19	Yes	-
RPA1	6117	51	0.425	0.865	74	-	-
EIF6	3692	67	0.700	0.876	316	Yes	-
ACO2	50	65	1.000	1.076	191	Yes	-
RUVBL1	8607	95	0.720	0.973	469	Yes	-
PSMD3	5709	100	0.986	1.106	201	Yes	-
EFTUD2	9343	93	0.883	0.956	108	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
TUBG1	7283	98	0.974	0.973	91	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
RUVBL2	10856	95	0.693	0.956	532	Yes	-
PSMC1	5700	51	0.840	1.018	137	Yes	-
PRMT3	10196	49	0.431	0.815	26	-	-
MTHFD1	4522	49	0.194	0.815	26	Yes	-

Interactions (88)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACO2	50	RPA1	6117	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
PSMD11	5717	RUVBL1	8607	pp	--	int.I2D: YeastLow
EFTUD2	9343	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
EFTUD2	9343	RUVBL2	10856	pp	--	int.I2D: BioGrid
ACTB	60	RUVBL1	8607	pp	--	int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMC1	5700	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
RPA1	6117	RUVBL1	8607	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1	6117	VARS	7407	pp	--	int.I2D: YeastLow
PSMB2	5690	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	PSMC1	5700	pp	--	int.I2D: BioGrid_Yeast
PSMB3	5691	PSMD3	5709	pp	--	int.I2D: YeastLow
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPA1	6117	RUVBL2	10856	pp	--	int.I2D: YeastLow
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB	60	PSMC1	5700	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
PSMC1	5700	RPA1	6117	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
PSMA1	5682	PSMA2	5683	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
RUVBL1	8607	RUVBL2	10856	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd; int.Ravasi: -; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
ACO2	50	EIF6	3692	pp	--	int.I2D: YeastLow
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1	4522	PRMT3	10196	pd	<	reg.ITFP.txt: no annot
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
PSMD3	5709	RUVBL2	10856	pp	--	int.I2D: YeastLow
VARS	7407	POLE4	56655	pd	<>	reg.ITFP.txt: no annot
PSMA2	5683	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
HNRNPC	3183	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	POLE4	56655	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
ACO2	50	PSMC1	5700	pp	--	int.I2D: YeastLow
PSMC1	5700	RUVBL2	10856	pp	--	int.I2D: YeastLow
PSMB7	5695	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMB3	5691	PSMC1	5700	pp	--	int.I2D: YeastLow
PSMB7	5695	POLE4	56655	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	VARS	7407	pd	<	reg.ITFP.txt: no annot
MTHFD1	4522	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
TUBG1	7283	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
POLR2F	5435	RUVBL2	10856	pd	<	reg.ITFP.txt: no annot
PSMB3	5691	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1	4522	RPA1	6117	pd	<	reg.ITFP.txt: no annot
VARS	7407	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMC1	5700	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
PSMA2	5683	PSMC1	5700	pp	--	int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow
PSMB2	5690	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
PSMD11	5717	RUVBL2	10856	pp	--	int.I2D: YeastLow
PSMB3	5691	POLE4	56655	pd	<	reg.ITFP.txt: no annot
VARS	7407	RUVBL2	10856	pd	<>	reg.ITFP.txt: no annot
ACO2	50	RUVBL1	8607	pp	--	int.I2D: YeastLow
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMA1	5682	PSMC1	5700	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct
ACTB	60	RPA1	6117	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMB3	5691	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMB7	5695	RPA1	6117	pd	<	reg.ITFP.txt: no annot
PSMC1	5700	RUVBL1	8607	pp	--	int.I2D: YeastLow
EIF6	3692	DDX51	317781	pd	<	reg.ITFP.txt: no annot
EIF6	3692	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	RUVBL2	10856	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
PSMB2	5690	PSMC1	5700	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
POLR2F	5435	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6	3692	RUVBL1	8607	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct

Related GO terms (276)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	3.05e-15	4.98e-11	6.766	8	21	50
GO:0000502	proteasome complex	1.08e-14	1.77e-10	6.551	8	22	58
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.83e-14	4.62e-10	6.387	8	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.83e-14	4.62e-10	6.387	8	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.28e-14	8.61e-10	6.280	8	24	70
GO:0005654	nucleoplasm	6.69e-14	1.09e-09	3.313	16	83	1095
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	7.49e-14	1.22e-09	6.220	8	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.39e-14	1.37e-09	6.200	8	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.17e-13	1.91e-09	6.143	8	23	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.45e-13	2.36e-09	6.106	8	25	79
GO:0000082	G1/S transition of mitotic cell cycle	4.27e-13	6.97e-09	5.351	9	33	150
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	6.09e-13	9.94e-09	5.855	8	23	94
GO:0000209	protein polyubiquitination	3.41e-12	5.57e-08	5.551	8	21	116
GO:0042981	regulation of apoptotic process	2.89e-11	4.72e-07	5.171	8	26	151
GO:0010467	gene expression	3.51e-11	5.73e-07	3.609	12	58	669
GO:0005839	proteasome core complex	3.73e-11	6.09e-07	7.561	5	11	18
GO:0004298	threonine-type endopeptidase activity	6.73e-11	1.10e-06	7.409	5	11	20
GO:0000278	mitotic cell cycle	9.61e-11	1.57e-06	4.095	10	52	398
GO:0034641	cellular nitrogen compound metabolic process	1.04e-10	1.69e-06	4.942	8	25	177
GO:0016071	mRNA metabolic process	6.53e-10	1.07e-05	4.609	8	34	223
GO:0016070	RNA metabolic process	1.47e-09	2.39e-05	4.461	8	34	247
GO:0016032	viral process	1.87e-09	3.05e-05	3.655	10	55	540
GO:0005829	cytosol	2.70e-08	4.41e-04	2.086	16	125	2562
GO:0043066	negative regulation of apoptotic process	1.17e-07	1.90e-03	3.651	8	30	433
GO:0005730	nucleolus	1.20e-07	1.96e-03	2.392	13	70	1684
GO:0005838	proteasome regulatory particle	6.09e-07	9.94e-03	7.409	3	7	12
GO:0006915	apoptotic process	9.57e-07	1.56e-02	3.252	8	34	571
GO:0035267	NuA4 histone acetyltransferase complex	1.01e-06	1.64e-02	7.187	3	4	14
GO:0022624	proteasome accessory complex	1.87e-06	3.06e-02	6.907	3	9	17
GO:0044281	small molecule metabolic process	6.67e-06	1.09e-01	2.393	10	57	1295
GO:0070062	extracellular vesicular exosome	1.25e-05	2.05e-01	1.813	13	98	2516
GO:0016020	membrane	1.35e-05	2.21e-01	2.099	11	80	1746
GO:0006281	DNA repair	3.52e-05	5.75e-01	3.687	5	22	264
GO:0005634	nucleus	3.54e-05	5.78e-01	1.260	17	131	4828
GO:0000812	Swr1 complex	5.77e-05	9.42e-01	7.409	2	3	8
GO:0019773	proteasome core complex, alpha-subunit complex	5.77e-05	9.42e-01	7.409	2	5	8
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	6.60e-05	1.00e+00	5.240	3	5	54
GO:0006310	DNA recombination	1.26e-04	1.00e+00	4.928	3	4	67
GO:0043968	histone H2A acetylation	1.36e-04	1.00e+00	6.825	2	3	12
GO:0031011	Ino80 complex	1.87e-04	1.00e+00	6.602	2	3	14
GO:0005515	protein binding	2.12e-04	1.00e+00	0.998	18	172	6127
GO:0003678	DNA helicase activity	3.49e-04	1.00e+00	6.162	2	3	19
GO:0043044	ATP-dependent chromatin remodeling	5.15e-04	1.00e+00	5.886	2	4	23
GO:0030529	ribonucleoprotein complex	6.04e-04	1.00e+00	4.162	3	8	114
GO:0071339	MLL1 complex	7.11e-04	1.00e+00	5.655	2	3	27
GO:0006325	chromatin organization	7.53e-04	1.00e+00	4.052	3	4	123
GO:0043967	histone H4 acetylation	7.65e-04	1.00e+00	5.602	2	3	28
GO:0031492	nucleosomal DNA binding	7.65e-04	1.00e+00	5.602	2	4	28
GO:0016887	ATPase activity	1.19e-03	1.00e+00	3.825	3	7	144
GO:0000054	ribosomal subunit export from nucleus	1.47e-03	1.00e+00	9.409	1	1	1
GO:0004486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	1.47e-03	1.00e+00	9.409	1	1	1
GO:0032508	DNA duplex unwinding	1.72e-03	1.00e+00	5.017	2	4	42
GO:0000398	mRNA splicing, via spliceosome	1.76e-03	1.00e+00	3.628	3	12	165
GO:0006283	transcription-coupled nucleotide-excision repair	2.06e-03	1.00e+00	4.886	2	8	46
GO:0040008	regulation of growth	2.53e-03	1.00e+00	4.737	2	3	51
GO:0003684	damaged DNA binding	2.53e-03	1.00e+00	4.737	2	11	51
GO:0005524	ATP binding	2.61e-03	1.00e+00	1.814	7	46	1354
GO:0004832	valine-tRNA ligase activity	2.94e-03	1.00e+00	8.409	1	1	2
GO:0051538	3 iron, 4 sulfur cluster binding	2.94e-03	1.00e+00	8.409	1	1	2
GO:0003994	aconitate hydratase activity	2.94e-03	1.00e+00	8.409	1	1	2
GO:0006438	valyl-tRNA aminoacylation	2.94e-03	1.00e+00	8.409	1	1	2
GO:0000105	histidine biosynthetic process	2.94e-03	1.00e+00	8.409	1	1	2
GO:0071899	negative regulation of estrogen receptor binding	4.41e-03	1.00e+00	7.825	1	1	3
GO:0071733	transcriptional activation by promoter-enhancer looping	4.41e-03	1.00e+00	7.825	1	1	3
GO:0006289	nucleotide-excision repair	4.58e-03	1.00e+00	4.301	2	12	69
GO:0008380	RNA splicing	4.60e-03	1.00e+00	3.136	3	13	232
GO:0000212	meiotic spindle organization	5.87e-03	1.00e+00	7.409	1	1	4
GO:0019788	NEDD8 ligase activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0016274	protein-arginine N-methyltransferase activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0004329	formate-tetrahydrofolate ligase activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0043141	ATP-dependent 5'-3' DNA helicase activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0034969	histone arginine methylation	5.87e-03	1.00e+00	7.409	1	1	4
GO:0009396	folic acid-containing compound biosynthetic process	5.87e-03	1.00e+00	7.409	1	1	4
GO:0004477	methenyltetrahydrofolate cyclohydrolase activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	5.87e-03	1.00e+00	7.409	1	1	4
GO:0071013	catalytic step 2 spliceosome	5.96e-03	1.00e+00	4.106	2	7	79
GO:0005681	spliceosomal complex	6.56e-03	1.00e+00	4.034	2	3	83
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	7.33e-03	1.00e+00	7.088	1	2	5
GO:0042256	mature ribosome assembly	7.33e-03	1.00e+00	7.088	1	1	5
GO:0009086	methionine biosynthetic process	7.33e-03	1.00e+00	7.088	1	1	5
GO:0008622	epsilon DNA polymerase complex	7.33e-03	1.00e+00	7.088	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	7.33e-03	1.00e+00	7.088	1	1	5
GO:0071169	establishment of protein localization to chromatin	7.33e-03	1.00e+00	7.088	1	1	5
GO:0043248	proteasome assembly	7.33e-03	1.00e+00	7.088	1	1	5
GO:0006102	isocitrate metabolic process	7.33e-03	1.00e+00	7.088	1	1	5
GO:0030891	VCB complex	7.33e-03	1.00e+00	7.088	1	2	5
GO:0005827	polar microtubule	7.33e-03	1.00e+00	7.088	1	1	5
GO:0000730	DNA recombinase assembly	7.33e-03	1.00e+00	7.088	1	3	5
GO:0005638	lamin filament	7.33e-03	1.00e+00	7.088	1	1	5
GO:0016363	nuclear matrix	8.00e-03	1.00e+00	3.886	2	11	92
GO:0005200	structural constituent of cytoskeleton	8.17e-03	1.00e+00	3.870	2	7	93
GO:0006101	citrate metabolic process	8.79e-03	1.00e+00	6.825	1	1	6
GO:0043023	ribosomal large subunit binding	8.79e-03	1.00e+00	6.825	1	2	6
GO:0031466	Cul5-RING ubiquitin ligase complex	8.79e-03	1.00e+00	6.825	1	1	6
GO:0030957	Tat protein binding	8.79e-03	1.00e+00	6.825	1	4	6
GO:0008469	histone-arginine N-methyltransferase activity	8.79e-03	1.00e+00	6.825	1	1	6
GO:0006200	ATP catabolic process	9.61e-03	1.00e+00	2.751	3	14	303
GO:0002161	aminoacyl-tRNA editing activity	1.03e-02	1.00e+00	6.602	1	2	7
GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity	1.03e-02	1.00e+00	6.602	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	1.03e-02	1.00e+00	6.602	1	2	7
GO:0035999	tetrahydrofolate interconversion	1.03e-02	1.00e+00	6.602	1	1	7
GO:0072341	modified amino acid binding	1.03e-02	1.00e+00	6.602	1	1	7
GO:0000930	gamma-tubulin complex	1.03e-02	1.00e+00	6.602	1	1	7
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	1.03e-02	1.00e+00	6.602	1	1	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.17e-02	1.00e+00	6.409	1	2	8
GO:0001055	RNA polymerase II activity	1.17e-02	1.00e+00	6.409	1	3	8
GO:0070688	MLL5-L complex	1.17e-02	1.00e+00	6.409	1	1	8
GO:0045116	protein neddylation	1.17e-02	1.00e+00	6.409	1	2	8
GO:0000800	lateral element	1.17e-02	1.00e+00	6.409	1	1	8
GO:0006164	purine nucleotide biosynthetic process	1.17e-02	1.00e+00	6.409	1	2	8
GO:0046655	folic acid metabolic process	1.46e-02	1.00e+00	6.088	1	1	10
GO:0006450	regulation of translational fidelity	1.46e-02	1.00e+00	6.088	1	2	10
GO:0001054	RNA polymerase I activity	1.61e-02	1.00e+00	5.950	1	3	11
GO:0045120	pronucleus	1.61e-02	1.00e+00	5.950	1	1	11
GO:0000790	nuclear chromatin	1.62e-02	1.00e+00	3.354	2	7	133
GO:0070935	3'-UTR-mediated mRNA stabilization	1.75e-02	1.00e+00	5.825	1	2	12
GO:0005736	DNA-directed RNA polymerase I complex	1.75e-02	1.00e+00	5.825	1	3	12
GO:0005737	cytoplasm	1.76e-02	1.00e+00	0.912	11	98	3976
GO:0042273	ribosomal large subunit biogenesis	1.90e-02	1.00e+00	5.709	1	4	13
GO:0005662	DNA replication factor A complex	1.90e-02	1.00e+00	5.709	1	3	13
GO:0030234	enzyme regulator activity	1.90e-02	1.00e+00	5.709	1	3	13
GO:0008266	poly(U) RNA binding	1.90e-02	1.00e+00	5.709	1	1	13
GO:0006457	protein folding	2.00e-02	1.00e+00	3.190	2	8	149
GO:0007020	microtubule nucleation	2.04e-02	1.00e+00	5.602	1	1	14
GO:0035066	positive regulation of histone acetylation	2.18e-02	1.00e+00	5.503	1	1	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	2.18e-02	1.00e+00	5.503	1	1	15
GO:0006261	DNA-dependent DNA replication	2.18e-02	1.00e+00	5.503	1	2	15
GO:0042176	regulation of protein catabolic process	2.33e-02	1.00e+00	5.409	1	3	16
GO:0005665	DNA-directed RNA polymerase II, core complex	2.33e-02	1.00e+00	5.409	1	4	16
GO:0050998	nitric-oxide synthase binding	2.33e-02	1.00e+00	5.409	1	1	16
GO:0001673	male germ cell nucleus	2.33e-02	1.00e+00	5.409	1	1	16
GO:0001056	RNA polymerase III activity	2.33e-02	1.00e+00	5.409	1	3	16
GO:0010243	response to organonitrogen compound	2.47e-02	1.00e+00	5.322	1	2	17
GO:0005666	DNA-directed RNA polymerase III complex	2.47e-02	1.00e+00	5.322	1	3	17
GO:0007126	meiotic nuclear division	2.47e-02	1.00e+00	5.322	1	1	17
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2.51e-02	1.00e+00	3.017	2	5	168
GO:0006386	termination of RNA polymerase III transcription	2.62e-02	1.00e+00	5.240	1	3	18
GO:0017025	TBP-class protein binding	2.62e-02	1.00e+00	5.240	1	2	18
GO:0071392	cellular response to estradiol stimulus	2.62e-02	1.00e+00	5.240	1	1	18
GO:0031122	cytoplasmic microtubule organization	2.62e-02	1.00e+00	5.240	1	2	18
GO:0006385	transcription elongation from RNA polymerase III promoter	2.62e-02	1.00e+00	5.240	1	3	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.76e-02	1.00e+00	5.162	1	1	19
GO:0048863	stem cell differentiation	2.76e-02	1.00e+00	5.162	1	1	19
GO:0048873	homeostasis of number of cells within a tissue	2.90e-02	1.00e+00	5.088	1	1	20
GO:0005719	nuclear euchromatin	2.90e-02	1.00e+00	5.088	1	2	20
GO:0006298	mismatch repair	2.90e-02	1.00e+00	5.088	1	6	20
GO:0015629	actin cytoskeleton	2.94e-02	1.00e+00	2.894	2	5	183
GO:0000718	nucleotide-excision repair, DNA damage removal	3.04e-02	1.00e+00	5.017	1	5	21
GO:0006297	nucleotide-excision repair, DNA gap filling	3.19e-02	1.00e+00	4.950	1	5	22
GO:0032201	telomere maintenance via semi-conservative replication	3.19e-02	1.00e+00	4.950	1	7	22
GO:0030863	cortical cytoskeleton	3.19e-02	1.00e+00	4.950	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	3.19e-02	1.00e+00	4.950	1	4	22
GO:0031463	Cul3-RING ubiquitin ligase complex	3.33e-02	1.00e+00	4.886	1	2	23
GO:0006513	protein monoubiquitination	3.33e-02	1.00e+00	4.886	1	1	23
GO:0000794	condensed nuclear chromosome	3.47e-02	1.00e+00	4.825	1	2	24
GO:0003924	GTPase activity	3.55e-02	1.00e+00	2.744	2	9	203
GO:0005844	polysome	3.61e-02	1.00e+00	4.766	1	4	25
GO:0000722	telomere maintenance via recombination	3.76e-02	1.00e+00	4.709	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.76e-02	1.00e+00	4.709	1	2	26
GO:0006730	one-carbon metabolic process	3.76e-02	1.00e+00	4.709	1	1	26
GO:0004003	ATP-dependent DNA helicase activity	3.90e-02	1.00e+00	4.655	1	3	27
GO:0034080	CENP-A containing nucleosome assembly	3.90e-02	1.00e+00	4.655	1	2	27
GO:0043022	ribosome binding	4.04e-02	1.00e+00	4.602	1	3	28
GO:0019894	kinesin binding	4.04e-02	1.00e+00	4.602	1	1	28
GO:0006184	GTP catabolic process	4.11e-02	1.00e+00	2.628	2	9	220
GO:0006099	tricarboxylic acid cycle	4.18e-02	1.00e+00	4.551	1	3	29
GO:0019005	SCF ubiquitin ligase complex	4.18e-02	1.00e+00	4.551	1	1	29
GO:0003730	mRNA 3'-UTR binding	4.18e-02	1.00e+00	4.551	1	2	29
GO:0003887	DNA-directed DNA polymerase activity	4.18e-02	1.00e+00	4.551	1	3	29
GO:0071897	DNA biosynthetic process	4.18e-02	1.00e+00	4.551	1	2	29
GO:0006370	7-methylguanosine mRNA capping	4.32e-02	1.00e+00	4.503	1	4	30
GO:0006360	transcription from RNA polymerase I promoter	4.32e-02	1.00e+00	4.503	1	4	30
GO:0006271	DNA strand elongation involved in DNA replication	4.46e-02	1.00e+00	4.455	1	9	31
GO:0031397	negative regulation of protein ubiquitination	4.60e-02	1.00e+00	4.409	1	1	32
GO:0034644	cellular response to UV	4.60e-02	1.00e+00	4.409	1	5	32
GO:0034332	adherens junction organization	5.17e-02	1.00e+00	4.240	1	1	36
GO:0001895	retina homeostasis	5.17e-02	1.00e+00	4.240	1	1	36
GO:0051084	'de novo' posttranslational protein folding	5.30e-02	1.00e+00	4.200	1	4	37
GO:0051539	4 iron, 4 sulfur cluster binding	5.30e-02	1.00e+00	4.200	1	3	37
GO:0070527	platelet aggregation	5.44e-02	1.00e+00	4.162	1	2	38
GO:0006383	transcription from RNA polymerase III promoter	5.58e-02	1.00e+00	4.124	1	3	39
GO:0008026	ATP-dependent helicase activity	5.58e-02	1.00e+00	4.124	1	3	39
GO:0031490	chromatin DNA binding	5.58e-02	1.00e+00	4.124	1	2	39
GO:0006284	base-excision repair	5.58e-02	1.00e+00	4.124	1	7	39
GO:0006418	tRNA aminoacylation for protein translation	6.00e-02	1.00e+00	4.017	1	5	42
GO:0014070	response to organic cyclic compound	6.14e-02	1.00e+00	3.983	1	3	43
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	6.28e-02	1.00e+00	3.950	1	2	44
GO:0050434	positive regulation of viral transcription	6.28e-02	1.00e+00	3.950	1	5	44
GO:0005739	mitochondrion	6.40e-02	1.00e+00	1.379	4	24	1046
GO:0015030	Cajal body	6.42e-02	1.00e+00	3.918	1	2	45
GO:0043966	histone H3 acetylation	6.42e-02	1.00e+00	3.918	1	2	45
GO:0021762	substantia nigra development	6.55e-02	1.00e+00	3.886	1	1	46
GO:0003743	translation initiation factor activity	6.97e-02	1.00e+00	3.795	1	4	49
GO:0044822	poly(A) RNA binding	7.00e-02	1.00e+00	1.335	4	50	1078
GO:0043234	protein complex	7.13e-02	1.00e+00	2.181	2	17	300
GO:0006091	generation of precursor metabolites and energy	7.24e-02	1.00e+00	3.737	1	3	51
GO:0008168	methyltransferase activity	7.38e-02	1.00e+00	3.709	1	1	52
GO:0000226	microtubule cytoskeleton organization	7.79e-02	1.00e+00	3.628	1	3	55
GO:0000932	cytoplasmic mRNA processing body	7.92e-02	1.00e+00	3.602	1	3	56
GO:0000724	double-strand break repair via homologous recombination	8.06e-02	1.00e+00	3.577	1	6	57
GO:0030097	hemopoiesis	8.19e-02	1.00e+00	3.551	1	3	58
GO:0005525	GTP binding	8.32e-02	1.00e+00	2.052	2	11	328
GO:0005840	ribosome	8.33e-02	1.00e+00	3.527	1	2	59
GO:0045216	cell-cell junction organization	8.33e-02	1.00e+00	3.527	1	2	59
GO:0000723	telomere maintenance	8.33e-02	1.00e+00	3.527	1	8	59
GO:0032481	positive regulation of type I interferon production	8.60e-02	1.00e+00	3.479	1	6	61
GO:0006302	double-strand break repair	8.74e-02	1.00e+00	3.455	1	8	62
GO:0005813	centrosome	8.80e-02	1.00e+00	2.004	2	12	339
GO:0006368	transcription elongation from RNA polymerase II promoter	9.41e-02	1.00e+00	3.343	1	6	67
GO:0003723	RNA binding	9.52e-02	1.00e+00	1.938	2	19	355
GO:0006338	chromatin remodeling	9.54e-02	1.00e+00	3.322	1	4	68
GO:0003697	single-stranded DNA binding	9.67e-02	1.00e+00	3.301	1	9	69
GO:0034329	cell junction assembly	9.94e-02	1.00e+00	3.260	1	1	71
GO:0006767	water-soluble vitamin metabolic process	1.05e-01	1.00e+00	3.181	1	3	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	1.06e-01	1.00e+00	3.162	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	1.07e-01	1.00e+00	3.143	1	5	77
GO:0006766	vitamin metabolic process	1.09e-01	1.00e+00	3.124	1	3	78
GO:0006334	nucleosome assembly	1.10e-01	1.00e+00	3.106	1	4	79
GO:0016605	PML body	1.27e-01	1.00e+00	2.886	1	5	92
GO:0006928	cellular component movement	1.27e-01	1.00e+00	2.886	1	7	92
GO:0051082	unfolded protein binding	1.31e-01	1.00e+00	2.840	1	6	95
GO:0001649	osteoblast differentiation	1.31e-01	1.00e+00	2.840	1	6	95
GO:0006364	rRNA processing	1.32e-01	1.00e+00	2.825	1	5	96
GO:0071456	cellular response to hypoxia	1.35e-01	1.00e+00	2.795	1	4	98
GO:0014069	postsynaptic density	1.45e-01	1.00e+00	2.682	1	1	106
GO:0005815	microtubule organizing center	1.50e-01	1.00e+00	2.628	1	4	110
GO:0015630	microtubule cytoskeleton	1.52e-01	1.00e+00	2.602	1	5	112
GO:0072562	blood microparticle	1.57e-01	1.00e+00	2.551	1	4	116
GO:0044237	cellular metabolic process	1.60e-01	1.00e+00	2.527	1	3	118
GO:0042802	identical protein binding	1.62e-01	1.00e+00	1.470	2	18	491
GO:0007219	Notch signaling pathway	1.69e-01	1.00e+00	2.444	1	4	125
GO:0006260	DNA replication	1.69e-01	1.00e+00	2.444	1	12	125
GO:0005506	iron ion binding	1.71e-01	1.00e+00	2.421	1	3	127
GO:0006511	ubiquitin-dependent protein catabolic process	1.71e-01	1.00e+00	2.421	1	5	127
GO:0006413	translational initiation	1.76e-01	1.00e+00	2.376	1	12	131
GO:0009615	response to virus	1.77e-01	1.00e+00	2.365	1	6	132
GO:0000086	G2/M transition of mitotic cell cycle	1.83e-01	1.00e+00	2.311	1	7	137
GO:0061024	membrane organization	1.94e-01	1.00e+00	2.220	1	5	146
GO:0006397	mRNA processing	2.21e-01	1.00e+00	2.009	1	3	169
GO:0030424	axon	2.25e-01	1.00e+00	1.983	1	3	172
GO:0016607	nuclear speck	2.28e-01	1.00e+00	1.958	1	4	175
GO:0045087	innate immune response	2.29e-01	1.00e+00	1.143	2	20	616
GO:0031625	ubiquitin protein ligase binding	2.34e-01	1.00e+00	1.918	1	13	180
GO:0006367	transcription initiation from RNA polymerase II promoter	2.38e-01	1.00e+00	1.886	1	8	184
GO:0032403	protein complex binding	2.40e-01	1.00e+00	1.878	1	7	185
GO:0005794	Golgi apparatus	2.48e-01	1.00e+00	1.065	2	14	650
GO:0001701	in utero embryonic development	2.67e-01	1.00e+00	1.695	1	6	210
GO:0005622	intracellular	2.85e-01	1.00e+00	1.589	1	5	226
GO:0007067	mitotic nuclear division	2.90e-01	1.00e+00	1.558	1	13	231
GO:0005759	mitochondrial matrix	2.92e-01	1.00e+00	1.545	1	12	233
GO:0004842	ubiquitin-protein transferase activity	3.16e-01	1.00e+00	1.409	1	4	256
GO:0000166	nucleotide binding	3.32e-01	1.00e+00	1.322	1	6	272
GO:0006357	regulation of transcription from RNA polymerase II promoter	3.35e-01	1.00e+00	1.306	1	6	275
GO:0007283	spermatogenesis	3.36e-01	1.00e+00	1.301	1	6	276
GO:0016567	protein ubiquitination	3.59e-01	1.00e+00	1.185	1	5	299
GO:0005856	cytoskeleton	3.70e-01	1.00e+00	1.129	1	8	311
GO:0019901	protein kinase binding	3.78e-01	1.00e+00	1.088	1	21	320
GO:0007411	axon guidance	3.85e-01	1.00e+00	1.056	1	9	327
GO:0043231	intracellular membrane-bounded organelle	3.90e-01	1.00e+00	1.034	1	8	332
GO:0003682	chromatin binding	3.91e-01	1.00e+00	1.026	1	12	334
GO:0043565	sequence-specific DNA binding	4.19e-01	1.00e+00	0.898	1	4	365
GO:0005925	focal adhesion	4.23e-01	1.00e+00	0.878	1	18	370
GO:0008284	positive regulation of cell proliferation	4.42e-01	1.00e+00	0.795	1	8	392
GO:0046982	protein heterodimerization activity	4.48e-01	1.00e+00	0.769	1	11	399
GO:0006366	transcription from RNA polymerase II promoter	4.69e-01	1.00e+00	0.678	1	12	425
GO:0007596	blood coagulation	5.00e-01	1.00e+00	0.551	1	14	464
GO:0055114	oxidation-reduction process	5.12e-01	1.00e+00	0.500	1	11	481
GO:0044267	cellular protein metabolic process	5.23e-01	1.00e+00	0.458	1	24	495
GO:0046872	metal ion binding	6.48e-01	1.00e+00	-0.107	2	24	1465
GO:0006351	transcription, DNA-templated	6.92e-01	1.00e+00	-0.221	2	25	1585
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	7.06e-01	1.00e+00	-0.254	1	19	811
GO:0005615	extracellular space	7.84e-01	1.00e+00	-0.571	1	17	1010
GO:0008270	zinc ion binding	8.03e-01	1.00e+00	-0.650	1	12	1067
GO:0006355	regulation of transcription, DNA-templated	8.14e-01	1.00e+00	-0.699	1	17	1104
GO:0003677	DNA binding	8.74e-01	1.00e+00	-0.990	1	26	1351

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-5700

Interacting subnets

Genes (24)

Interactions (88)

Related GO terms (276)