Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-56655 | wolf-screen-ratio-mammosphere-adherent | 0.828 | 9.29e-07 | 2.91e-03 | 5.53e-03 | 8 | 7 |
int-snw-1460 | wolf-screen-ratio-mammosphere-adherent | 0.978 | 3.10e-17 | 9.28e-04 | 1.95e-02 | 13 | 12 |
reg-snw-317781 | wolf-screen-ratio-mammosphere-adherent | 0.823 | 1.13e-06 | 3.23e-03 | 6.07e-03 | 9 | 9 |
reg-snw-5925 | wolf-screen-ratio-mammosphere-adherent | 0.802 | 2.42e-06 | 4.82e-03 | 8.69e-03 | 8 | 5 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
PPCS | 79717 | 31 | -0.569 | 0.802 | 2 | - | Yes |
PSMA2 | 5683 | 112 | 1.093 | 1.106 | 108 | Yes | - |
RBX1 | 9978 | 115 | 1.185 | 0.934 | 148 | Yes | - |
PPIE | 10450 | 31 | 0.567 | 0.802 | 41 | - | - |
PSMB7 | 5695 | 118 | 0.982 | 0.934 | 90 | Yes | - |
VARS | 7407 | 86 | 0.549 | 1.002 | 204 | Yes | - |
CSNK2B | 1460 | 4 | -0.064 | 0.978 | 217 | - | - |
OGDH | 4967 | 72 | 0.847 | 0.802 | 126 | Yes | - |
DDX51 | 317781 | 53 | 0.059 | 0.823 | 210 | Yes | - |
POLE4 | 56655 | 63 | 0.177 | 0.828 | 56 | - | - |
TFRC | 7037 | 31 | 0.730 | 0.802 | 17 | - | - |
RPSA | 3921 | 120 | 1.327 | 1.151 | 152 | Yes | - |
PSMB3 | 5691 | 64 | 0.668 | 0.901 | 19 | Yes | - |
PGD | 5226 | 89 | 1.201 | 1.106 | 152 | Yes | - |
ADH5 | 128 | 16 | 0.633 | 0.994 | 43 | Yes | - |
RPA2 | 6118 | 96 | 1.250 | 1.151 | 76 | Yes | - |
EIF6 | 3692 | 67 | 0.700 | 0.876 | 316 | Yes | - |
RB1 | 5925 | 31 | -0.102 | 0.802 | 351 | - | - |
RSL24D1 | 51187 | 38 | 1.300 | 1.020 | 59 | Yes | - |
EIF2S2 | 8894 | 39 | 1.075 | 0.940 | 103 | Yes | - |
PPP2R1A | 5518 | 19 | 0.644 | 0.985 | 249 | Yes | - |
PSMD3 | 5709 | 100 | 0.986 | 1.106 | 201 | Yes | - |
PSMB2 | 5690 | 116 | 0.877 | 0.956 | 169 | Yes | - |
TUBG1 | 7283 | 98 | 0.974 | 0.973 | 91 | Yes | - |
PSMD11 | 5717 | 124 | 1.095 | 1.106 | 218 | Yes | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PPP2R1A | 5518 | PSMB3 | 5691 | pp | -- | int.I2D: IntAct_Mouse |
RB1 | 5925 | PPCS | 79717 | pd | > | reg.pazar.txt: no annot |
RB1 | 5925 | RPA2 | 6118 | pd | > | reg.pazar.txt: no annot |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
ACTB | 60 | CSNK2B | 1460 | pp | -- | int.Intact: MI:0915(physical association) |
PSMB2 | 5690 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMB3 | 5691 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PGD | 5226 | RB1 | 5925 | pd | < | reg.pazar.txt: no annot |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
RBX1 | 9978 | PPIE | 10450 | pd | <> | reg.ITFP.txt: no annot |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
EIF6 | 3692 | OGDH | 4967 | pp | -- | int.I2D: YeastLow |
RPSA | 3921 | VARS | 7407 | pp | -- | int.I2D: IntAct_Yeast |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
EIF6 | 3692 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
CSNK2B | 1460 | EIF6 | 3692 | pp | -- | int.I2D: BioGrid, MINT; int.Mint: MI:0915(physical association) |
TUBG1 | 7283 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
ADH5 | 128 | CSNK2B | 1460 | pp | -- | int.Intact: MI:0915(physical association) |
OGDH | 4967 | RB1 | 5925 | pd | < | reg.ITFP.txt: no annot |
PPP2R1A | 5518 | PSMB2 | 5690 | pp | -- | int.I2D: IntAct_Mouse |
CSNK2B | 1460 | PPP2R1A | 5518 | pp | -- | int.I2D: IntAct_Mouse |
ACTB | 60 | PPP2R1A | 5518 | pp | -- | int.I2D: BioGrid_Yeast |
OGDH | 4967 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
PSMB7 | 5695 | RBX1 | 9978 | pd | < | reg.ITFP.txt: no annot |
PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
VARS | 7407 | POLE4 | 56655 | pd | <> | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd |
PSMD3 | 5709 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
PPP2R1A | 5518 | PSMB7 | 5695 | pp | -- | int.I2D: IntAct_Mouse |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RB1 | 5925 | pd | < | reg.ITFP.txt: no annot |
PSMA2 | 5683 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PGD | 5226 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMB7 | 5695 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
PSMB7 | 5695 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
PSMB3 | 5691 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid |
PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
VARS | 7407 | DDX51 | 317781 | pd | <> | reg.ITFP.txt: no annot |
PSMD3 | 5709 | VARS | 7407 | pd | <> | reg.ITFP.txt: no annot |
PGD | 5226 | PPP2R1A | 5518 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMD11 | 5717 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
EIF6 | 3692 | RSL24D1 | 51187 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB2 | 5690 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
OGDH | 4967 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMB2 | 5690 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
OGDH | 4967 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMB3 | 5691 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
CSNK2B | 1460 | EIF2S2 | 8894 | pp | -- | int.I2D: BIND, BCI, HPRD; int.HPRD: in vitro |
PSMB7 | 5695 | PPIE | 10450 | pd | < | reg.ITFP.txt: no annot |
PPP2R1A | 5518 | PSMA2 | 5683 | pp | -- | int.I2D: IntAct_Mouse |
RB1 | 5925 | TFRC | 7037 | pd | > | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMD11 | 5717 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB2 | 5690 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
PSMB3 | 5691 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
RB1 | 5925 | PPIE | 10450 | pd | > | reg.pazar.txt: no annot |
EIF6 | 3692 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
EIF6 | 3692 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
EIF6 | 3692 | PPP2R1A | 5518 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMD11 | 5717 | EIF2S2 | 8894 | pd | > | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0000278 | mitotic cell cycle | 8.79e-12 | 1.44e-07 | 4.117 | 11 | 52 | 398 |
GO:0000082 | G1/S transition of mitotic cell cycle | 5.73e-11 | 9.35e-07 | 5.065 | 8 | 33 | 150 |
GO:0006521 | regulation of cellular amino acid metabolic process | 1.33e-10 | 2.17e-06 | 6.235 | 6 | 21 | 50 |
GO:0000502 | proteasome complex | 3.36e-10 | 5.49e-06 | 6.021 | 6 | 22 | 58 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.81e-10 | 1.11e-05 | 5.857 | 6 | 24 | 65 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 6.81e-10 | 1.11e-05 | 5.857 | 6 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.08e-09 | 1.76e-05 | 5.750 | 6 | 24 | 70 |
GO:0016071 | mRNA metabolic process | 1.35e-09 | 2.21e-05 | 4.493 | 8 | 34 | 223 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.39e-09 | 2.27e-05 | 5.689 | 6 | 23 | 73 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.51e-09 | 2.47e-05 | 5.670 | 6 | 24 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.93e-09 | 3.15e-05 | 5.612 | 6 | 23 | 77 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.26e-09 | 3.69e-05 | 5.575 | 6 | 25 | 79 |
GO:0016070 | RNA metabolic process | 3.03e-09 | 4.95e-05 | 4.346 | 8 | 34 | 247 |
GO:0016032 | viral process | 4.77e-09 | 7.78e-05 | 3.539 | 10 | 55 | 540 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 6.52e-09 | 1.06e-04 | 5.324 | 6 | 23 | 94 |
GO:0034641 | cellular nitrogen compound metabolic process | 8.66e-09 | 1.41e-04 | 4.634 | 7 | 25 | 177 |
GO:0005839 | proteasome core complex | 1.52e-08 | 2.49e-04 | 7.124 | 4 | 11 | 18 |
GO:0000209 | protein polyubiquitination | 2.32e-08 | 3.79e-04 | 5.021 | 6 | 21 | 116 |
GO:0004298 | threonine-type endopeptidase activity | 2.41e-08 | 3.93e-04 | 6.972 | 4 | 11 | 20 |
GO:0010467 | gene expression | 3.67e-08 | 5.99e-04 | 3.230 | 10 | 58 | 669 |
GO:0042981 | regulation of apoptotic process | 1.12e-07 | 1.83e-03 | 4.641 | 6 | 26 | 151 |
GO:0005829 | cytosol | 1.42e-07 | 2.32e-03 | 1.971 | 16 | 125 | 2562 |
GO:0070062 | extracellular vesicular exosome | 8.97e-07 | 1.46e-02 | 1.904 | 15 | 98 | 2516 |
GO:0005654 | nucleoplasm | 3.50e-06 | 5.70e-02 | 2.519 | 10 | 83 | 1095 |
GO:0006915 | apoptotic process | 2.28e-05 | 3.72e-01 | 2.944 | 7 | 34 | 571 |
GO:0043066 | negative regulation of apoptotic process | 4.94e-05 | 8.06e-01 | 3.121 | 6 | 30 | 433 |
GO:0044281 | small molecule metabolic process | 1.10e-04 | 1.00e+00 | 2.125 | 9 | 57 | 1295 |
GO:0005838 | proteasome regulatory particle | 1.59e-04 | 1.00e+00 | 6.709 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 3.27e-04 | 1.00e+00 | 6.207 | 2 | 9 | 17 |
GO:0005634 | nucleus | 7.10e-04 | 1.00e+00 | 1.057 | 16 | 131 | 4828 |
GO:0043022 | ribosome binding | 8.99e-04 | 1.00e+00 | 5.487 | 2 | 3 | 28 |
GO:0005515 | protein binding | 1.04e-03 | 1.00e+00 | 0.883 | 18 | 172 | 6127 |
GO:0006413 | translational initiation | 1.15e-03 | 1.00e+00 | 3.846 | 3 | 12 | 131 |
GO:0018467 | formaldehyde dehydrogenase activity | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0051903 | S-(hydroxymethyl)glutathione dehydrogenase activity | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0005956 | protein kinase CK2 complex | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0090230 | regulation of centromere complex assembly | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0070262 | peptidyl-serine dephosphorylation | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0004632 | phosphopantothenate--cysteine ligase activity | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0000054 | ribosomal subunit export from nucleus | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 1.59e-03 | 1.00e+00 | 9.294 | 1 | 1 | 1 |
GO:0003743 | translation initiation factor activity | 2.74e-03 | 1.00e+00 | 4.679 | 2 | 4 | 49 |
GO:0031625 | ubiquitin protein ligase binding | 2.85e-03 | 1.00e+00 | 3.387 | 3 | 13 | 180 |
GO:0004832 | valine-tRNA ligase activity | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0045252 | oxoglutarate dehydrogenase complex | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 2 | 2 |
GO:0002176 | male germ cell proliferation | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0097286 | iron ion import | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0046294 | formaldehyde catabolic process | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0061034 | olfactory bulb mitral cell layer development | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0004998 | transferrin receptor activity | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0031134 | sister chromatid biorientation | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 1 | 2 |
GO:0007070 | negative regulation of transcription from RNA polymerase II promoter during mitosis | 3.18e-03 | 1.00e+00 | 8.294 | 1 | 2 | 2 |
GO:0016020 | membrane | 4.51e-03 | 1.00e+00 | 1.524 | 8 | 80 | 1746 |
GO:0018119 | peptidyl-cysteine S-nitrosylation | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0022028 | tangential migration from the subventricular zone to the olfactory bulb | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0071459 | protein localization to chromosome, centromeric region | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0005850 | eukaryotic translation initiation factor 2 complex | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle | 4.77e-03 | 1.00e+00 | 7.709 | 1 | 1 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0000212 | meiotic spindle organization | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0071922 | regulation of cohesin localization to chromatin | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0051409 | response to nitrosative stress | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0006068 | ethanol catabolic process | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0006104 | succinyl-CoA metabolic process | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0043550 | regulation of lipid kinase activity | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0035189 | Rb-E2F complex | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0034349 | glial cell apoptotic process | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0034088 | maintenance of mitotic sister chromatid cohesion | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 1 | 4 |
GO:0019887 | protein kinase regulator activity | 6.36e-03 | 1.00e+00 | 7.294 | 1 | 2 | 4 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 2 | 5 |
GO:0019932 | second-messenger-mediated signaling | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0042256 | mature ribosome assembly | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0051101 | regulation of DNA binding | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0008622 | epsilon DNA polymerase complex | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0061154 | endothelial tube morphogenesis | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0048667 | cell morphogenesis involved in neuron differentiation | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0004022 | alcohol dehydrogenase (NAD) activity | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 2 | 5 |
GO:0005827 | polar microtubule | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0000730 | DNA recombinase assembly | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 3 | 5 |
GO:0005638 | lamin filament | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0006734 | NADH metabolic process | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0030976 | thiamine pyrophosphate binding | 7.94e-03 | 1.00e+00 | 6.972 | 1 | 1 | 5 |
GO:0016605 | PML body | 9.35e-03 | 1.00e+00 | 3.770 | 2 | 5 | 92 |
GO:0043353 | enucleate erythrocyte differentiation | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0009108 | coenzyme biosynthetic process | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0045842 | positive regulation of mitotic metaphase/anaphase transition | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0032927 | positive regulation of activin receptor signaling pathway | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0021860 | pyramidal neuron development | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0043023 | ribosomal large subunit binding | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 2 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0021695 | cerebellar cortex development | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 4 | 6 |
GO:0033211 | adiponectin-activated signaling pathway | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 6 |
GO:0005200 | structural constituent of cytoskeleton | 9.55e-03 | 1.00e+00 | 3.755 | 2 | 7 | 93 |
GO:0000028 | ribosomal small subunit assembly | 1.11e-02 | 1.00e+00 | 6.487 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 1.11e-02 | 1.00e+00 | 6.487 | 1 | 2 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 1.11e-02 | 1.00e+00 | 6.487 | 1 | 2 | 7 |
GO:0000930 | gamma-tubulin complex | 1.11e-02 | 1.00e+00 | 6.487 | 1 | 1 | 7 |
GO:0016018 | cyclosporin A binding | 1.11e-02 | 1.00e+00 | 6.487 | 1 | 1 | 7 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 1.27e-02 | 1.00e+00 | 6.294 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 1.27e-02 | 1.00e+00 | 6.294 | 1 | 1 | 8 |
GO:0006554 | lysine catabolic process | 1.27e-02 | 1.00e+00 | 6.294 | 1 | 2 | 8 |
GO:0045116 | protein neddylation | 1.27e-02 | 1.00e+00 | 6.294 | 1 | 2 | 8 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 1.27e-02 | 1.00e+00 | 6.294 | 1 | 5 | 8 |
GO:0015630 | microtubule cytoskeleton | 1.36e-02 | 1.00e+00 | 3.487 | 2 | 5 | 112 |
GO:0005730 | nucleolus | 1.39e-02 | 1.00e+00 | 1.384 | 7 | 70 | 1684 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.41e-02 | 1.00e+00 | 3.461 | 2 | 10 | 114 |
GO:0003016 | respiratory system process | 1.42e-02 | 1.00e+00 | 6.124 | 1 | 1 | 9 |
GO:0015937 | coenzyme A biosynthetic process | 1.42e-02 | 1.00e+00 | 6.124 | 1 | 1 | 9 |
GO:0097284 | hepatocyte apoptotic process | 1.42e-02 | 1.00e+00 | 6.124 | 1 | 2 | 9 |
GO:0000075 | cell cycle checkpoint | 1.42e-02 | 1.00e+00 | 6.124 | 1 | 2 | 9 |
GO:0072562 | blood microparticle | 1.46e-02 | 1.00e+00 | 3.436 | 2 | 4 | 116 |
GO:0006450 | regulation of translational fidelity | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 2 | 10 |
GO:0007084 | mitotic nuclear envelope reassembly | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 1 | 10 |
GO:0015939 | pantothenate metabolic process | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 1 | 10 |
GO:0006069 | ethanol oxidation | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 1 | 10 |
GO:0051775 | response to redox state | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 1 | 10 |
GO:0021756 | striatum development | 1.58e-02 | 1.00e+00 | 5.972 | 1 | 1 | 10 |
GO:0006098 | pentose-phosphate shunt | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 3 | 11 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 3 | 11 |
GO:0042551 | neuron maturation | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 2 | 11 |
GO:0045651 | positive regulation of macrophage differentiation | 1.74e-02 | 1.00e+00 | 5.835 | 1 | 2 | 11 |
GO:0051146 | striated muscle cell differentiation | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 1 | 12 |
GO:0006275 | regulation of DNA replication | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 2 | 12 |
GO:0021794 | thalamus development | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 1 | 12 |
GO:0030111 | regulation of Wnt signaling pathway | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 1 | 12 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.99e-02 | 1.00e+00 | 3.196 | 2 | 7 | 137 |
GO:0042273 | ribosomal large subunit biogenesis | 2.05e-02 | 1.00e+00 | 5.594 | 1 | 4 | 13 |
GO:0005662 | DNA replication factor A complex | 2.05e-02 | 1.00e+00 | 5.594 | 1 | 3 | 13 |
GO:0045780 | positive regulation of bone resorption | 2.05e-02 | 1.00e+00 | 5.594 | 1 | 1 | 13 |
GO:0043537 | negative regulation of blood vessel endothelial cell migration | 2.05e-02 | 1.00e+00 | 5.594 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 2.05e-02 | 1.00e+00 | 5.594 | 1 | 3 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 2.21e-02 | 1.00e+00 | 5.487 | 1 | 4 | 14 |
GO:0005504 | fatty acid binding | 2.21e-02 | 1.00e+00 | 5.487 | 1 | 1 | 14 |
GO:0007020 | microtubule nucleation | 2.21e-02 | 1.00e+00 | 5.487 | 1 | 1 | 14 |
GO:0005739 | mitochondrion | 2.28e-02 | 1.00e+00 | 1.585 | 5 | 24 | 1046 |
GO:0006457 | protein folding | 2.33e-02 | 1.00e+00 | 3.075 | 2 | 8 | 149 |
GO:0006672 | ceramide metabolic process | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 15 |
GO:0045445 | myoblast differentiation | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 2 | 15 |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 2 | 15 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 1 | 15 |
GO:0016514 | SWI/SNF complex | 2.36e-02 | 1.00e+00 | 5.387 | 1 | 3 | 15 |
GO:0042176 | regulation of protein catabolic process | 2.52e-02 | 1.00e+00 | 5.294 | 1 | 3 | 16 |
GO:0043623 | cellular protein complex assembly | 2.52e-02 | 1.00e+00 | 5.294 | 1 | 1 | 16 |
GO:0050998 | nitric-oxide synthase binding | 2.52e-02 | 1.00e+00 | 5.294 | 1 | 1 | 16 |
GO:0006103 | 2-oxoglutarate metabolic process | 2.52e-02 | 1.00e+00 | 5.294 | 1 | 1 | 16 |
GO:0044822 | poly(A) RNA binding | 2.56e-02 | 1.00e+00 | 1.542 | 5 | 50 | 1078 |
GO:0010243 | response to organonitrogen compound | 2.68e-02 | 1.00e+00 | 5.207 | 1 | 2 | 17 |
GO:0045070 | positive regulation of viral genome replication | 2.68e-02 | 1.00e+00 | 5.207 | 1 | 1 | 17 |
GO:0045777 | positive regulation of blood pressure | 2.68e-02 | 1.00e+00 | 5.207 | 1 | 1 | 17 |
GO:0031122 | cytoplasmic microtubule organization | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 2 | 18 |
GO:0035861 | site of double-strand break | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.99e-02 | 1.00e+00 | 5.046 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 2.99e-02 | 1.00e+00 | 5.046 | 1 | 1 | 19 |
GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 3.14e-02 | 1.00e+00 | 4.972 | 1 | 2 | 20 |
GO:0008601 | protein phosphatase type 2A regulator activity | 3.14e-02 | 1.00e+00 | 4.972 | 1 | 3 | 20 |
GO:0006298 | mismatch repair | 3.14e-02 | 1.00e+00 | 4.972 | 1 | 6 | 20 |
GO:0000159 | protein phosphatase type 2A complex | 3.14e-02 | 1.00e+00 | 4.972 | 1 | 2 | 20 |
GO:0045595 | regulation of cell differentiation | 3.29e-02 | 1.00e+00 | 4.902 | 1 | 1 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 3.29e-02 | 1.00e+00 | 4.902 | 1 | 5 | 21 |
GO:0030316 | osteoclast differentiation | 3.45e-02 | 1.00e+00 | 4.835 | 1 | 2 | 22 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 3.45e-02 | 1.00e+00 | 4.835 | 1 | 5 | 22 |
GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle | 3.45e-02 | 1.00e+00 | 4.835 | 1 | 3 | 22 |
GO:0032201 | telomere maintenance via semi-conservative replication | 3.45e-02 | 1.00e+00 | 4.835 | 1 | 7 | 22 |
GO:0030863 | cortical cytoskeleton | 3.45e-02 | 1.00e+00 | 4.835 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 3.45e-02 | 1.00e+00 | 4.835 | 1 | 4 | 22 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 3.60e-02 | 1.00e+00 | 4.770 | 1 | 2 | 23 |
GO:0043236 | laminin binding | 3.60e-02 | 1.00e+00 | 4.770 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 3.60e-02 | 1.00e+00 | 4.770 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 3.60e-02 | 1.00e+00 | 4.770 | 1 | 4 | 23 |
GO:0045879 | negative regulation of smoothened signaling pathway | 3.60e-02 | 1.00e+00 | 4.770 | 1 | 1 | 23 |
GO:0008135 | translation factor activity, nucleic acid binding | 3.76e-02 | 1.00e+00 | 4.709 | 1 | 4 | 24 |
GO:0000794 | condensed nuclear chromosome | 3.76e-02 | 1.00e+00 | 4.709 | 1 | 2 | 24 |
GO:0031519 | PcG protein complex | 3.91e-02 | 1.00e+00 | 4.650 | 1 | 4 | 25 |
GO:0000722 | telomere maintenance via recombination | 4.06e-02 | 1.00e+00 | 4.594 | 1 | 7 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 4.06e-02 | 1.00e+00 | 4.594 | 1 | 2 | 26 |
GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation | 4.06e-02 | 1.00e+00 | 4.594 | 1 | 1 | 26 |
GO:0045859 | regulation of protein kinase activity | 4.06e-02 | 1.00e+00 | 4.594 | 1 | 1 | 26 |
GO:0042802 | identical protein binding | 4.21e-02 | 1.00e+00 | 1.939 | 3 | 18 | 491 |
GO:0000188 | inactivation of MAPK activity | 4.22e-02 | 1.00e+00 | 4.539 | 1 | 1 | 27 |
GO:0048565 | digestive tract development | 4.22e-02 | 1.00e+00 | 4.539 | 1 | 1 | 27 |
GO:0044267 | cellular protein metabolic process | 4.30e-02 | 1.00e+00 | 1.928 | 3 | 24 | 495 |
GO:0003823 | antigen binding | 4.37e-02 | 1.00e+00 | 4.487 | 1 | 1 | 28 |
GO:0010033 | response to organic substance | 4.37e-02 | 1.00e+00 | 4.487 | 1 | 2 | 28 |
GO:0031492 | nucleosomal DNA binding | 4.37e-02 | 1.00e+00 | 4.487 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 4.37e-02 | 1.00e+00 | 4.487 | 1 | 1 | 28 |
GO:0006099 | tricarboxylic acid cycle | 4.52e-02 | 1.00e+00 | 4.436 | 1 | 3 | 29 |
GO:0019005 | SCF ubiquitin ligase complex | 4.52e-02 | 1.00e+00 | 4.436 | 1 | 1 | 29 |
GO:0003887 | DNA-directed DNA polymerase activity | 4.52e-02 | 1.00e+00 | 4.436 | 1 | 3 | 29 |
GO:0071897 | DNA biosynthetic process | 4.52e-02 | 1.00e+00 | 4.436 | 1 | 2 | 29 |
GO:0042254 | ribosome biogenesis | 4.67e-02 | 1.00e+00 | 4.387 | 1 | 1 | 30 |
GO:0007346 | regulation of mitotic cell cycle | 4.67e-02 | 1.00e+00 | 4.387 | 1 | 3 | 30 |
GO:0006271 | DNA strand elongation involved in DNA replication | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 9 | 31 |
GO:0007093 | mitotic cell cycle checkpoint | 4.83e-02 | 1.00e+00 | 4.340 | 1 | 2 | 31 |
GO:0050661 | NADP binding | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 1 | 32 |
GO:0051219 | phosphoprotein binding | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 3 | 32 |
GO:0033572 | transferrin transport | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 6 | 32 |
GO:0031072 | heat shock protein binding | 5.13e-02 | 1.00e+00 | 4.250 | 1 | 2 | 33 |
GO:0000413 | protein peptidyl-prolyl isomerization | 5.28e-02 | 1.00e+00 | 4.207 | 1 | 1 | 34 |
GO:0003755 | peptidyl-prolyl cis-trans isomerase activity | 5.28e-02 | 1.00e+00 | 4.207 | 1 | 1 | 34 |
GO:0006412 | translation | 5.35e-02 | 1.00e+00 | 2.417 | 2 | 15 | 235 |
GO:0034332 | adherens junction organization | 5.58e-02 | 1.00e+00 | 4.124 | 1 | 1 | 36 |
GO:0051402 | neuron apoptotic process | 5.58e-02 | 1.00e+00 | 4.124 | 1 | 2 | 36 |
GO:0001895 | retina homeostasis | 5.58e-02 | 1.00e+00 | 4.124 | 1 | 1 | 36 |
GO:0001102 | RNA polymerase II activating transcription factor binding | 5.73e-02 | 1.00e+00 | 4.085 | 1 | 4 | 37 |
GO:0051084 | 'de novo' posttranslational protein folding | 5.73e-02 | 1.00e+00 | 4.085 | 1 | 4 | 37 |
GO:0008134 | transcription factor binding | 5.80e-02 | 1.00e+00 | 2.351 | 2 | 8 | 246 |
GO:0070527 | platelet aggregation | 5.88e-02 | 1.00e+00 | 4.046 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 5.88e-02 | 1.00e+00 | 4.046 | 1 | 4 | 38 |
GO:0021766 | hippocampus development | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 4 | 39 |
GO:0008026 | ATP-dependent helicase activity | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 3 | 39 |
GO:0006284 | base-excision repair | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 7 | 39 |
GO:0006096 | glycolytic process | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 4 | 39 |
GO:0022627 | cytosolic small ribosomal subunit | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 3 | 39 |
GO:0000781 | chromosome, telomeric region | 6.19e-02 | 1.00e+00 | 3.972 | 1 | 2 | 40 |
GO:0030521 | androgen receptor signaling pathway | 6.34e-02 | 1.00e+00 | 3.936 | 1 | 2 | 41 |
GO:0006418 | tRNA aminoacylation for protein translation | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 5 | 42 |
GO:0004722 | protein serine/threonine phosphatase activity | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 1 | 42 |
GO:0035914 | skeletal muscle cell differentiation | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 1 | 42 |
GO:0030155 | regulation of cell adhesion | 6.48e-02 | 1.00e+00 | 3.902 | 1 | 3 | 42 |
GO:0006281 | DNA repair | 6.57e-02 | 1.00e+00 | 2.250 | 2 | 22 | 264 |
GO:0014070 | response to organic cyclic compound | 6.63e-02 | 1.00e+00 | 3.868 | 1 | 3 | 43 |
GO:0043966 | histone H3 acetylation | 6.93e-02 | 1.00e+00 | 3.802 | 1 | 2 | 45 |
GO:0021762 | substantia nigra development | 7.08e-02 | 1.00e+00 | 3.770 | 1 | 1 | 46 |
GO:0001047 | core promoter binding | 7.08e-02 | 1.00e+00 | 3.770 | 1 | 2 | 46 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 7.08e-02 | 1.00e+00 | 3.770 | 1 | 8 | 46 |
GO:0001523 | retinoid metabolic process | 7.67e-02 | 1.00e+00 | 3.650 | 1 | 2 | 50 |
GO:0006091 | generation of precursor metabolites and energy | 7.82e-02 | 1.00e+00 | 3.622 | 1 | 3 | 51 |
GO:0005905 | coated pit | 7.82e-02 | 1.00e+00 | 3.622 | 1 | 2 | 51 |
GO:0040008 | regulation of growth | 7.82e-02 | 1.00e+00 | 3.622 | 1 | 3 | 51 |
GO:0003684 | damaged DNA binding | 7.82e-02 | 1.00e+00 | 3.622 | 1 | 11 | 51 |
GO:0000775 | chromosome, centromeric region | 7.97e-02 | 1.00e+00 | 3.594 | 1 | 2 | 52 |
GO:0003725 | double-stranded RNA binding | 8.26e-02 | 1.00e+00 | 3.539 | 1 | 6 | 54 |
GO:0019900 | kinase binding | 8.26e-02 | 1.00e+00 | 3.539 | 1 | 1 | 54 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 8.26e-02 | 1.00e+00 | 3.539 | 1 | 5 | 54 |
GO:0050680 | negative regulation of epithelial cell proliferation | 8.26e-02 | 1.00e+00 | 3.539 | 1 | 1 | 54 |
GO:0000226 | microtubule cytoskeleton organization | 8.41e-02 | 1.00e+00 | 3.513 | 1 | 3 | 55 |
GO:0000932 | cytoplasmic mRNA processing body | 8.55e-02 | 1.00e+00 | 3.487 | 1 | 3 | 56 |
GO:0006879 | cellular iron ion homeostasis | 8.70e-02 | 1.00e+00 | 3.461 | 1 | 5 | 57 |
GO:0000724 | double-strand break repair via homologous recombination | 8.70e-02 | 1.00e+00 | 3.461 | 1 | 6 | 57 |
GO:0051087 | chaperone binding | 8.99e-02 | 1.00e+00 | 3.411 | 1 | 6 | 59 |
GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity | 8.99e-02 | 1.00e+00 | 3.411 | 1 | 4 | 59 |
GO:0045216 | cell-cell junction organization | 8.99e-02 | 1.00e+00 | 3.411 | 1 | 2 | 59 |
GO:0000723 | telomere maintenance | 8.99e-02 | 1.00e+00 | 3.411 | 1 | 8 | 59 |
GO:0031966 | mitochondrial membrane | 8.99e-02 | 1.00e+00 | 3.411 | 1 | 1 | 59 |
GO:0006302 | double-strand break repair | 9.43e-02 | 1.00e+00 | 3.340 | 1 | 8 | 62 |
GO:0007411 | axon guidance | 9.50e-02 | 1.00e+00 | 1.941 | 2 | 9 | 327 |
GO:0019903 | protein phosphatase binding | 9.57e-02 | 1.00e+00 | 3.317 | 1 | 4 | 63 |
GO:0007059 | chromosome segregation | 9.72e-02 | 1.00e+00 | 3.294 | 1 | 3 | 64 |
GO:0006469 | negative regulation of protein kinase activity | 9.86e-02 | 1.00e+00 | 3.272 | 1 | 2 | 65 |
GO:0001558 | regulation of cell growth | 1.00e-01 | 1.00e+00 | 3.250 | 1 | 4 | 66 |
GO:0006338 | chromatin remodeling | 1.03e-01 | 1.00e+00 | 3.207 | 1 | 4 | 68 |
GO:0009055 | electron carrier activity | 1.03e-01 | 1.00e+00 | 3.207 | 1 | 1 | 68 |
GO:0006289 | nucleotide-excision repair | 1.04e-01 | 1.00e+00 | 3.185 | 1 | 12 | 69 |
GO:0003697 | single-stranded DNA binding | 1.04e-01 | 1.00e+00 | 3.185 | 1 | 9 | 69 |
GO:0034329 | cell junction assembly | 1.07e-01 | 1.00e+00 | 3.144 | 1 | 1 | 71 |
GO:0003723 | RNA binding | 1.09e-01 | 1.00e+00 | 1.822 | 2 | 19 | 355 |
GO:0055037 | recycling endosome | 1.10e-01 | 1.00e+00 | 3.104 | 1 | 2 | 73 |
GO:0000785 | chromatin | 1.10e-01 | 1.00e+00 | 3.104 | 1 | 5 | 73 |
GO:0006767 | water-soluble vitamin metabolic process | 1.13e-01 | 1.00e+00 | 3.065 | 1 | 3 | 75 |
GO:0007265 | Ras protein signal transduction | 1.13e-01 | 1.00e+00 | 3.065 | 1 | 3 | 75 |
GO:0031175 | neuron projection development | 1.13e-01 | 1.00e+00 | 3.065 | 1 | 1 | 75 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 1.14e-01 | 1.00e+00 | 3.046 | 1 | 3 | 76 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.16e-01 | 1.00e+00 | 3.027 | 1 | 5 | 77 |
GO:0008584 | male gonad development | 1.16e-01 | 1.00e+00 | 3.027 | 1 | 2 | 77 |
GO:0006766 | vitamin metabolic process | 1.17e-01 | 1.00e+00 | 3.009 | 1 | 3 | 78 |
GO:0071013 | catalytic step 2 spliceosome | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 7 | 79 |
GO:0019083 | viral transcription | 1.21e-01 | 1.00e+00 | 2.954 | 1 | 8 | 81 |
GO:0047485 | protein N-terminus binding | 1.28e-01 | 1.00e+00 | 2.868 | 1 | 4 | 86 |
GO:0006898 | receptor-mediated endocytosis | 1.28e-01 | 1.00e+00 | 2.868 | 1 | 2 | 86 |
GO:0006415 | translational termination | 1.30e-01 | 1.00e+00 | 2.851 | 1 | 8 | 87 |
GO:0046982 | protein heterodimerization activity | 1.32e-01 | 1.00e+00 | 1.654 | 2 | 11 | 399 |
GO:0042470 | melanosome | 1.37e-01 | 1.00e+00 | 2.770 | 1 | 10 | 92 |
GO:0006928 | cellular component movement | 1.37e-01 | 1.00e+00 | 2.770 | 1 | 7 | 92 |
GO:0006414 | translational elongation | 1.38e-01 | 1.00e+00 | 2.755 | 1 | 11 | 93 |
GO:0006364 | rRNA processing | 1.42e-01 | 1.00e+00 | 2.709 | 1 | 5 | 96 |
GO:0071456 | cellular response to hypoxia | 1.45e-01 | 1.00e+00 | 2.679 | 1 | 4 | 98 |
GO:0006470 | protein dephosphorylation | 1.46e-01 | 1.00e+00 | 2.665 | 1 | 1 | 99 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.53e-01 | 1.00e+00 | 2.594 | 1 | 8 | 104 |
GO:0014069 | postsynaptic density | 1.56e-01 | 1.00e+00 | 2.566 | 1 | 1 | 106 |
GO:0016023 | cytoplasmic membrane-bounded vesicle | 1.57e-01 | 1.00e+00 | 2.553 | 1 | 3 | 107 |
GO:0042127 | regulation of cell proliferation | 1.63e-01 | 1.00e+00 | 2.500 | 1 | 4 | 111 |
GO:0006461 | protein complex assembly | 1.63e-01 | 1.00e+00 | 2.500 | 1 | 6 | 111 |
GO:0030308 | negative regulation of cell growth | 1.65e-01 | 1.00e+00 | 2.474 | 1 | 6 | 113 |
GO:0030529 | ribonucleoprotein complex | 1.67e-01 | 1.00e+00 | 2.461 | 1 | 8 | 114 |
GO:0005819 | spindle | 1.67e-01 | 1.00e+00 | 2.461 | 1 | 7 | 114 |
GO:0019058 | viral life cycle | 1.68e-01 | 1.00e+00 | 2.449 | 1 | 10 | 115 |
GO:0044237 | cellular metabolic process | 1.72e-01 | 1.00e+00 | 2.411 | 1 | 3 | 118 |
GO:0032496 | response to lipopolysaccharide | 1.77e-01 | 1.00e+00 | 2.363 | 1 | 4 | 122 |
GO:0006325 | chromatin organization | 1.79e-01 | 1.00e+00 | 2.351 | 1 | 4 | 123 |
GO:0007568 | aging | 1.79e-01 | 1.00e+00 | 2.351 | 1 | 3 | 123 |
GO:0007219 | Notch signaling pathway | 1.81e-01 | 1.00e+00 | 2.328 | 1 | 4 | 125 |
GO:0006260 | DNA replication | 1.81e-01 | 1.00e+00 | 2.328 | 1 | 12 | 125 |
GO:0007050 | cell cycle arrest | 1.83e-01 | 1.00e+00 | 2.317 | 1 | 7 | 126 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.84e-01 | 1.00e+00 | 2.305 | 1 | 5 | 127 |
GO:0009615 | response to virus | 1.90e-01 | 1.00e+00 | 2.250 | 1 | 6 | 132 |
GO:0000790 | nuclear chromatin | 1.92e-01 | 1.00e+00 | 2.239 | 1 | 7 | 133 |
GO:0031982 | vesicle | 1.93e-01 | 1.00e+00 | 2.228 | 1 | 10 | 134 |
GO:0003735 | structural constituent of ribosome | 2.02e-01 | 1.00e+00 | 2.154 | 1 | 8 | 141 |
GO:0016055 | Wnt signaling pathway | 2.02e-01 | 1.00e+00 | 2.154 | 1 | 6 | 141 |
GO:0061024 | membrane organization | 2.08e-01 | 1.00e+00 | 2.104 | 1 | 5 | 146 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 2.25e-01 | 1.00e+00 | 1.981 | 1 | 4 | 159 |
GO:0000398 | mRNA splicing, via spliceosome | 2.32e-01 | 1.00e+00 | 1.928 | 1 | 12 | 165 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2.36e-01 | 1.00e+00 | 1.902 | 1 | 5 | 168 |
GO:0030424 | axon | 2.41e-01 | 1.00e+00 | 1.868 | 1 | 3 | 172 |
GO:0005768 | endosome | 2.43e-01 | 1.00e+00 | 1.851 | 1 | 5 | 174 |
GO:0019904 | protein domain specific binding | 2.52e-01 | 1.00e+00 | 1.794 | 1 | 6 | 181 |
GO:0009897 | external side of plasma membrane | 2.54e-01 | 1.00e+00 | 1.778 | 1 | 4 | 183 |
GO:0015629 | actin cytoskeleton | 2.54e-01 | 1.00e+00 | 1.778 | 1 | 5 | 183 |
GO:0032403 | protein complex binding | 2.57e-01 | 1.00e+00 | 1.763 | 1 | 7 | 185 |
GO:0003924 | GTPase activity | 2.78e-01 | 1.00e+00 | 1.629 | 1 | 9 | 203 |
GO:0001701 | in utero embryonic development | 2.86e-01 | 1.00e+00 | 1.580 | 1 | 6 | 210 |
GO:0006184 | GTP catabolic process | 2.98e-01 | 1.00e+00 | 1.513 | 1 | 9 | 220 |
GO:0008380 | RNA splicing | 3.11e-01 | 1.00e+00 | 1.436 | 1 | 13 | 232 |
GO:0005759 | mitochondrial matrix | 3.12e-01 | 1.00e+00 | 1.430 | 1 | 12 | 233 |
GO:0003713 | transcription coactivator activity | 3.19e-01 | 1.00e+00 | 1.393 | 1 | 10 | 239 |
GO:0004842 | ubiquitin-protein transferase activity | 3.37e-01 | 1.00e+00 | 1.294 | 1 | 4 | 256 |
GO:0005102 | receptor binding | 3.50e-01 | 1.00e+00 | 1.228 | 1 | 5 | 268 |
GO:0000166 | nucleotide binding | 3.54e-01 | 1.00e+00 | 1.207 | 1 | 6 | 272 |
GO:0005975 | carbohydrate metabolic process | 3.56e-01 | 1.00e+00 | 1.196 | 1 | 5 | 274 |
GO:0005524 | ATP binding | 3.67e-01 | 1.00e+00 | 0.476 | 3 | 46 | 1354 |
GO:0019899 | enzyme binding | 3.71e-01 | 1.00e+00 | 1.124 | 1 | 11 | 288 |
GO:0016567 | protein ubiquitination | 3.82e-01 | 1.00e+00 | 1.070 | 1 | 5 | 299 |
GO:0043234 | protein complex | 3.83e-01 | 1.00e+00 | 1.065 | 1 | 17 | 300 |
GO:0006200 | ATP catabolic process | 3.86e-01 | 1.00e+00 | 1.051 | 1 | 14 | 303 |
GO:0005856 | cytoskeleton | 3.94e-01 | 1.00e+00 | 1.013 | 1 | 8 | 311 |
GO:0004674 | protein serine/threonine kinase activity | 3.95e-01 | 1.00e+00 | 1.009 | 1 | 6 | 312 |
GO:0019901 | protein kinase binding | 4.03e-01 | 1.00e+00 | 0.972 | 1 | 21 | 320 |
GO:0005525 | GTP binding | 4.10e-01 | 1.00e+00 | 0.936 | 1 | 11 | 328 |
GO:0043231 | intracellular membrane-bounded organelle | 4.14e-01 | 1.00e+00 | 0.919 | 1 | 8 | 332 |
GO:0046872 | metal ion binding | 4.17e-01 | 1.00e+00 | 0.362 | 3 | 24 | 1465 |
GO:0005813 | centrosome | 4.21e-01 | 1.00e+00 | 0.889 | 1 | 12 | 339 |
GO:0043565 | sequence-specific DNA binding | 4.45e-01 | 1.00e+00 | 0.782 | 1 | 4 | 365 |
GO:0008285 | negative regulation of cell proliferation | 4.47e-01 | 1.00e+00 | 0.774 | 1 | 11 | 367 |
GO:0005925 | focal adhesion | 4.49e-01 | 1.00e+00 | 0.763 | 1 | 18 | 370 |
GO:0005737 | cytoplasm | 4.54e-01 | 1.00e+00 | 0.144 | 7 | 98 | 3976 |
GO:0007155 | cell adhesion | 4.62e-01 | 1.00e+00 | 0.709 | 1 | 8 | 384 |
GO:0005615 | extracellular space | 4.84e-01 | 1.00e+00 | 0.314 | 2 | 17 | 1010 |
GO:0009986 | cell surface | 4.94e-01 | 1.00e+00 | 0.573 | 1 | 9 | 422 |
GO:0045892 | negative regulation of transcription, DNA-templated | 4.96e-01 | 1.00e+00 | 0.566 | 1 | 14 | 424 |
GO:0008270 | zinc ion binding | 5.14e-01 | 1.00e+00 | 0.235 | 2 | 12 | 1067 |
GO:0007596 | blood coagulation | 5.28e-01 | 1.00e+00 | 0.436 | 1 | 14 | 464 |
GO:0006468 | protein phosphorylation | 5.30e-01 | 1.00e+00 | 0.427 | 1 | 10 | 467 |
GO:0006355 | regulation of transcription, DNA-templated | 5.33e-01 | 1.00e+00 | 0.185 | 2 | 17 | 1104 |
GO:0055114 | oxidation-reduction process | 5.41e-01 | 1.00e+00 | 0.384 | 1 | 11 | 481 |
GO:0045893 | positive regulation of transcription, DNA-templated | 5.45e-01 | 1.00e+00 | 0.366 | 1 | 17 | 487 |
GO:0055085 | transmembrane transport | 5.65e-01 | 1.00e+00 | 0.288 | 1 | 8 | 514 |
GO:0048471 | perinuclear region of cytoplasm | 5.71e-01 | 1.00e+00 | 0.263 | 1 | 12 | 523 |
GO:0042803 | protein homodimerization activity | 6.33e-01 | 1.00e+00 | 0.025 | 1 | 11 | 617 |
GO:0045087 | innate immune response | 6.33e-01 | 1.00e+00 | 0.027 | 1 | 20 | 616 |
GO:0005794 | Golgi apparatus | 6.53e-01 | 1.00e+00 | -0.050 | 1 | 14 | 650 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 7.05e-01 | 1.00e+00 | -0.253 | 1 | 11 | 748 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 7.35e-01 | 1.00e+00 | -0.370 | 1 | 19 | 811 |
GO:0007165 | signal transduction | 7.90e-01 | 1.00e+00 | -0.598 | 1 | 17 | 950 |
GO:0005887 | integral component of plasma membrane | 7.94e-01 | 1.00e+00 | -0.614 | 1 | 7 | 961 |
GO:0005576 | extracellular region | 8.22e-01 | 1.00e+00 | -0.741 | 1 | 9 | 1049 |
GO:0005886 | plasma membrane | 8.54e-01 | 1.00e+00 | -0.590 | 3 | 38 | 2834 |
GO:0003677 | DNA binding | 8.94e-01 | 1.00e+00 | -1.106 | 1 | 26 | 1351 |
GO:0006351 | transcription, DNA-templated | 9.30e-01 | 1.00e+00 | -1.336 | 1 | 25 | 1585 |