Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.985 | 1.74e-17 | 8.04e-04 | 1.75e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PPP2R1A | 5518 | 9 | 0.644 | 0.985 | 249 | Yes | - |
CLTC | 1213 | 35 | 0.884 | 1.138 | 247 | Yes | - |
[ RAC1 ] | 5879 | 1 | 0.103 | 0.985 | 245 | Yes | - |
RPL14 | 9045 | 42 | 1.250 | 1.113 | 143 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - |
RPS3A | 6189 | 11 | 0.835 | 1.069 | 166 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
ACTB | 60 | RAC1 | 5879 | pp | -- | int.I2D: BCI, BioGrid, HPRD; int.HPRD: in vitro, in vivo |
PGD | 5226 | PPP2R1A | 5518 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
RPS3A | 6189 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
PPP2R1A | 5518 | RAC1 | 5879 | pp | -- | int.I2D: BioGrid_Fly |
ACTB | 60 | RPS3A | 6189 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | PPP2R1A | 5518 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | RAC1 | 5879 | pp | -- | int.I2D: SOURAV_MAPK_LOW, IntAct |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RAC1 | 5879 | RPS3A | 6189 | pp | -- | int.I2D: IntAct, SOURAV_MAPK_LOW |
ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
CLTC | 1213 | RAC1 | 5879 | pp | -- | int.I2D: BioGrid_Fly, BIND_Fly, FlyEmbryo, IntAct_Fly |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.17e-06 | 1.69e-02 | 5.524 | 4 | 11 | 114 |
GO:0005829 | cytosol | 5.40e-06 | 7.79e-02 | 2.241 | 9 | 132 | 2496 |
GO:0016071 | mRNA metabolic process | 1.69e-05 | 2.43e-01 | 4.556 | 4 | 31 | 223 |
GO:0016070 | RNA metabolic process | 2.52e-05 | 3.64e-01 | 4.408 | 4 | 32 | 247 |
GO:0016032 | viral process | 2.62e-05 | 3.78e-01 | 3.618 | 5 | 55 | 534 |
GO:0019083 | viral transcription | 2.73e-05 | 3.93e-01 | 5.602 | 3 | 10 | 81 |
GO:0006415 | translational termination | 3.38e-05 | 4.87e-01 | 5.499 | 3 | 10 | 87 |
GO:0006414 | translational elongation | 4.13e-05 | 5.95e-01 | 5.402 | 3 | 13 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 5.76e-05 | 8.31e-01 | 5.241 | 3 | 10 | 104 |
GO:0070062 | extracellular vesicular exosome | 5.96e-05 | 8.59e-01 | 2.128 | 8 | 104 | 2400 |
GO:0019058 | viral life cycle | 7.78e-05 | 1.00e+00 | 5.096 | 3 | 13 | 115 |
GO:0006413 | translational initiation | 1.15e-04 | 1.00e+00 | 4.908 | 3 | 17 | 131 |
GO:0005925 | focal adhesion | 1.17e-04 | 1.00e+00 | 3.841 | 4 | 19 | 366 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.21e-04 | 1.00e+00 | 6.897 | 2 | 4 | 22 |
GO:0003735 | structural constituent of ribosome | 1.31e-04 | 1.00e+00 | 4.844 | 3 | 10 | 137 |
GO:0044267 | cellular protein metabolic process | 3.16e-04 | 1.00e+00 | 3.468 | 4 | 29 | 474 |
GO:0022627 | cytosolic small ribosomal subunit | 3.86e-04 | 1.00e+00 | 6.071 | 2 | 4 | 39 |
GO:0006412 | translation | 6.01e-04 | 1.00e+00 | 4.096 | 3 | 20 | 230 |
GO:0016020 | membrane | 6.82e-04 | 1.00e+00 | 2.227 | 6 | 90 | 1681 |
GO:0045216 | cell-cell junction organization | 7.41e-04 | 1.00e+00 | 5.602 | 2 | 2 | 54 |
GO:0021831 | embryonic olfactory bulb interneuron precursor migration | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0048532 | anatomical structure arrangement | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0070262 | peptidyl-serine dephosphorylation | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 7.63e-04 | 1.00e+00 | 10.357 | 1 | 1 | 1 |
GO:0010467 | gene expression | 1.17e-03 | 1.00e+00 | 2.971 | 4 | 59 | 669 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.39e-03 | 1.00e+00 | 5.147 | 2 | 6 | 74 |
GO:0019901 | protein kinase binding | 1.52e-03 | 1.00e+00 | 3.633 | 3 | 21 | 317 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0051668 | localization within membrane | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0043652 | engulfment of apoptotic cell | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0003994 | aconitate hydratase activity | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0032707 | negative regulation of interleukin-23 production | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0051022 | Rho GDP-dissociation inhibitor binding | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 2 | 2 |
GO:0005055 | laminin receptor activity | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0002093 | auditory receptor cell morphogenesis | 1.52e-03 | 1.00e+00 | 9.357 | 1 | 1 | 2 |
GO:0042470 | melanosome | 2.09e-03 | 1.00e+00 | 4.849 | 2 | 9 | 91 |
GO:0006928 | cellular component movement | 2.09e-03 | 1.00e+00 | 4.849 | 2 | 7 | 91 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 1 | 3 |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 2 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 2 | 3 |
GO:0071439 | clathrin complex | 2.29e-03 | 1.00e+00 | 8.772 | 1 | 2 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0010310 | regulation of hydrogen peroxide metabolic process | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0032051 | clathrin light chain binding | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0002551 | mast cell chemotaxis | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0060263 | regulation of respiratory burst | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:1903077 | negative regulation of protein localization to plasma membrane | 3.05e-03 | 1.00e+00 | 8.357 | 1 | 1 | 4 |
GO:0030529 | ribonucleoprotein complex | 3.14e-03 | 1.00e+00 | 4.549 | 2 | 8 | 112 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 3 | 5 |
GO:0019932 | second-messenger-mediated signaling | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 3.81e-03 | 1.00e+00 | 8.035 | 1 | 1 | 5 |
GO:0002181 | cytoplasmic translation | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 3 | 6 |
GO:0006101 | citrate metabolic process | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0030118 | clathrin coat | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 2 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0048261 | negative regulation of receptor-mediated endocytosis | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 3 | 6 |
GO:0097178 | ruffle assembly | 4.57e-03 | 1.00e+00 | 7.772 | 1 | 1 | 6 |
GO:0061024 | membrane organization | 5.20e-03 | 1.00e+00 | 4.177 | 2 | 7 | 145 |
GO:0000028 | ribosomal small subunit assembly | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 2 | 7 |
GO:0030132 | clathrin coat of coated pit | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 2 | 7 |
GO:0021799 | cerebral cortex radially oriented cell migration | 5.33e-03 | 1.00e+00 | 7.549 | 1 | 2 | 7 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 6.09e-03 | 1.00e+00 | 7.357 | 1 | 2 | 8 |
GO:0044822 | poly(A) RNA binding | 6.21e-03 | 1.00e+00 | 2.312 | 4 | 49 | 1056 |
GO:0003382 | epithelial cell morphogenesis | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 9 |
GO:0006972 | hyperosmotic response | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 1 | 9 |
GO:0006098 | pentose-phosphate shunt | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 4 | 10 |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 2 | 10 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 10 |
GO:0007084 | mitotic nuclear envelope reassembly | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 10 |
GO:0035025 | positive regulation of Rho protein signal transduction | 7.60e-03 | 1.00e+00 | 7.035 | 1 | 1 | 10 |
GO:0031625 | ubiquitin protein ligase binding | 7.74e-03 | 1.00e+00 | 3.881 | 2 | 14 | 178 |
GO:0005515 | protein binding | 8.30e-03 | 1.00e+00 | 0.970 | 9 | 184 | 6024 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 4 | 11 |
GO:0010592 | positive regulation of lamellipodium assembly | 8.36e-03 | 1.00e+00 | 6.897 | 1 | 1 | 11 |
GO:0006275 | regulation of DNA replication | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 2 | 12 |
GO:0030111 | regulation of Wnt signaling pathway | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 12 |
GO:0071542 | dopaminergic neuron differentiation | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 12 |
GO:0006672 | ceramide metabolic process | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 13 |
GO:0042273 | ribosomal large subunit biogenesis | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 4 | 13 |
GO:0005662 | DNA replication factor A complex | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 1 | 13 |
GO:0001891 | phagocytic cup | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 2 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 4 | 14 |
GO:0031996 | thioesterase binding | 1.06e-02 | 1.00e+00 | 6.549 | 1 | 1 | 14 |
GO:0048870 | cell motility | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 15 |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 2 | 15 |
GO:0031529 | ruffle organization | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 16 |
GO:0030742 | GTP-dependent protein binding | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 1 | 17 |
GO:0051894 | positive regulation of focal adhesion assembly | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 18 |
GO:0035861 | site of double-strand break | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 18 |
GO:0090023 | positive regulation of neutrophil chemotaxis | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 1 | 19 |
GO:0071526 | semaphorin-plexin signaling pathway | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 1 | 19 |
GO:0045453 | bone resorption | 1.44e-02 | 1.00e+00 | 6.109 | 1 | 2 | 19 |
GO:0019897 | extrinsic component of plasma membrane | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 2 | 20 |
GO:0008601 | protein phosphatase type 2A regulator activity | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 2 | 20 |
GO:0090103 | cochlea morphogenesis | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 2 | 20 |
GO:0006298 | mismatch repair | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 3 | 20 |
GO:0000159 | protein phosphatase type 2A complex | 1.52e-02 | 1.00e+00 | 6.035 | 1 | 2 | 20 |
GO:0045595 | regulation of cell differentiation | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 1 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 4 | 21 |
GO:0030041 | actin filament polymerization | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 3 | 21 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.59e-02 | 1.00e+00 | 5.964 | 1 | 5 | 21 |
GO:0006281 | DNA repair | 1.61e-02 | 1.00e+00 | 3.329 | 2 | 18 | 261 |
GO:0003823 | antigen binding | 1.67e-02 | 1.00e+00 | 5.897 | 1 | 1 | 22 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.67e-02 | 1.00e+00 | 5.897 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 1.67e-02 | 1.00e+00 | 5.897 | 1 | 1 | 22 |
GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 2 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.74e-02 | 1.00e+00 | 5.833 | 1 | 4 | 23 |
GO:0019899 | enzyme binding | 1.80e-02 | 1.00e+00 | 3.243 | 2 | 12 | 277 |
GO:0000722 | telomere maintenance via recombination | 1.89e-02 | 1.00e+00 | 5.713 | 1 | 5 | 25 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 3 | 26 |
GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 2 | 26 |
GO:0043234 | protein complex | 2.03e-02 | 1.00e+00 | 3.152 | 2 | 18 | 295 |
GO:0010033 | response to organic substance | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 2 | 27 |
GO:0050661 | NADP binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 2 | 27 |
GO:0000188 | inactivation of MAPK activity | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 27 |
GO:0050690 | regulation of defense response to virus by virus | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 4 | 27 |
GO:0043022 | ribosome binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 4 | 27 |
GO:0006099 | tricarboxylic acid cycle | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 4 | 28 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.19e-02 | 1.00e+00 | 5.499 | 1 | 1 | 29 |
GO:0030032 | lamellipodium assembly | 2.19e-02 | 1.00e+00 | 5.499 | 1 | 2 | 29 |
GO:0033572 | transferrin transport | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 5 | 30 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 7 | 30 |
GO:0048813 | dendrite morphogenesis | 2.27e-02 | 1.00e+00 | 5.450 | 1 | 1 | 30 |
GO:0010811 | positive regulation of cell-substrate adhesion | 2.34e-02 | 1.00e+00 | 5.402 | 1 | 2 | 31 |
GO:0031623 | receptor internalization | 2.34e-02 | 1.00e+00 | 5.402 | 1 | 2 | 31 |
GO:0007411 | axon guidance | 2.35e-02 | 1.00e+00 | 3.039 | 2 | 13 | 319 |
GO:0032588 | trans-Golgi network membrane | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 2 | 34 |
GO:0001895 | retina homeostasis | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 1 | 34 |
GO:0030838 | positive regulation of actin filament polymerization | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 2 | 34 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 2.64e-02 | 1.00e+00 | 5.227 | 1 | 3 | 35 |
GO:0003723 | RNA binding | 2.68e-02 | 1.00e+00 | 2.939 | 2 | 20 | 342 |
GO:0034332 | adherens junction organization | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 36 |
GO:0034446 | substrate adhesion-dependent cell spreading | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 36 |
GO:0045740 | positive regulation of DNA replication | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 2.79e-02 | 1.00e+00 | 5.147 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 2.79e-02 | 1.00e+00 | 5.147 | 1 | 3 | 37 |
GO:0051496 | positive regulation of stress fiber assembly | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 2 | 38 |
GO:0070527 | platelet aggregation | 2.86e-02 | 1.00e+00 | 5.109 | 1 | 2 | 38 |
GO:0072659 | protein localization to plasma membrane | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 1 | 39 |
GO:0000781 | chromosome, telomeric region | 2.94e-02 | 1.00e+00 | 5.071 | 1 | 3 | 39 |
GO:0007155 | cell adhesion | 3.08e-02 | 1.00e+00 | 2.829 | 2 | 6 | 369 |
GO:0030136 | clathrin-coated vesicle | 3.16e-02 | 1.00e+00 | 4.964 | 1 | 4 | 42 |
GO:0004722 | protein serine/threonine phosphatase activity | 3.16e-02 | 1.00e+00 | 4.964 | 1 | 1 | 42 |
GO:0030155 | regulation of cell adhesion | 3.16e-02 | 1.00e+00 | 4.964 | 1 | 2 | 42 |
GO:0006892 | post-Golgi vesicle-mediated transport | 3.23e-02 | 1.00e+00 | 4.930 | 1 | 3 | 43 |
GO:0021762 | substantia nigra development | 3.31e-02 | 1.00e+00 | 4.897 | 1 | 2 | 44 |
GO:0005884 | actin filament | 3.31e-02 | 1.00e+00 | 4.897 | 1 | 2 | 44 |
GO:0000278 | mitotic cell cycle | 3.43e-02 | 1.00e+00 | 2.746 | 2 | 48 | 391 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.45e-02 | 1.00e+00 | 4.833 | 1 | 7 | 46 |
GO:0022625 | cytosolic large ribosomal subunit | 3.68e-02 | 1.00e+00 | 4.742 | 1 | 6 | 49 |
GO:0003684 | damaged DNA binding | 3.68e-02 | 1.00e+00 | 4.742 | 1 | 7 | 49 |
GO:0006091 | generation of precursor metabolites and energy | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 3 | 50 |
GO:0000775 | chromosome, centromeric region | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 2 | 50 |
GO:0040008 | regulation of growth | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 5 | 50 |
GO:0030334 | regulation of cell migration | 3.75e-02 | 1.00e+00 | 4.713 | 1 | 2 | 50 |
GO:0003725 | double-stranded RNA binding | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 5 | 52 |
GO:0009611 | response to wounding | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 1 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3.97e-02 | 1.00e+00 | 4.629 | 1 | 5 | 53 |
GO:0000724 | double-strand break repair via homologous recombination | 4.12e-02 | 1.00e+00 | 4.575 | 1 | 3 | 55 |
GO:0000723 | telomere maintenance | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 6 | 56 |
GO:0005654 | nucleoplasm | 4.41e-02 | 1.00e+00 | 1.862 | 3 | 76 | 1082 |
GO:0007596 | blood coagulation | 4.52e-02 | 1.00e+00 | 2.527 | 2 | 18 | 455 |
GO:0007059 | chromosome segregation | 4.63e-02 | 1.00e+00 | 4.402 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 4.63e-02 | 1.00e+00 | 4.402 | 1 | 4 | 62 |
GO:0019903 | protein phosphatase binding | 4.63e-02 | 1.00e+00 | 4.402 | 1 | 4 | 62 |
GO:0031295 | T cell costimulation | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 2 | 65 |
GO:0006289 | nucleotide-excision repair | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 11 | 68 |
GO:0003697 | single-stranded DNA binding | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 5 | 68 |
GO:0034329 | cell junction assembly | 5.07e-02 | 1.00e+00 | 4.269 | 1 | 1 | 68 |
GO:0032587 | ruffle membrane | 5.21e-02 | 1.00e+00 | 4.227 | 1 | 3 | 70 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 5.58e-02 | 1.00e+00 | 4.128 | 1 | 2 | 75 |
GO:0017137 | Rab GTPase binding | 5.65e-02 | 1.00e+00 | 4.109 | 1 | 2 | 76 |
GO:0007160 | cell-matrix adhesion | 6.08e-02 | 1.00e+00 | 3.999 | 1 | 3 | 82 |
GO:0009653 | anatomical structure morphogenesis | 6.15e-02 | 1.00e+00 | 3.982 | 1 | 3 | 83 |
GO:0006898 | receptor-mediated endocytosis | 6.23e-02 | 1.00e+00 | 3.964 | 1 | 3 | 84 |
GO:0047485 | protein N-terminus binding | 6.37e-02 | 1.00e+00 | 3.930 | 1 | 5 | 86 |
GO:0016605 | PML body | 6.51e-02 | 1.00e+00 | 3.897 | 1 | 3 | 88 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 6.66e-02 | 1.00e+00 | 3.865 | 1 | 7 | 90 |
GO:0005200 | structural constituent of cytoskeleton | 6.73e-02 | 1.00e+00 | 3.849 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 6.80e-02 | 1.00e+00 | 3.833 | 1 | 6 | 92 |
GO:0071456 | cellular response to hypoxia | 6.80e-02 | 1.00e+00 | 3.833 | 1 | 6 | 92 |
GO:0006364 | rRNA processing | 6.94e-02 | 1.00e+00 | 3.802 | 1 | 6 | 94 |
GO:0006470 | protein dephosphorylation | 7.23e-02 | 1.00e+00 | 3.742 | 1 | 1 | 98 |
GO:0045087 | innate immune response | 7.32e-02 | 1.00e+00 | 2.137 | 2 | 24 | 596 |
GO:0001934 | positive regulation of protein phosphorylation | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 6 | 104 |
GO:0014069 | postsynaptic density | 7.73e-02 | 1.00e+00 | 3.642 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 7.73e-02 | 1.00e+00 | 3.642 | 1 | 4 | 105 |
GO:0005802 | trans-Golgi network | 8.08e-02 | 1.00e+00 | 3.575 | 1 | 2 | 110 |
GO:0030308 | negative regulation of cell growth | 8.08e-02 | 1.00e+00 | 3.575 | 1 | 6 | 110 |
GO:0015630 | microtubule cytoskeleton | 8.08e-02 | 1.00e+00 | 3.575 | 1 | 4 | 110 |
GO:0006461 | protein complex assembly | 8.15e-02 | 1.00e+00 | 3.562 | 1 | 6 | 111 |
GO:0072562 | blood microparticle | 8.15e-02 | 1.00e+00 | 3.562 | 1 | 3 | 111 |
GO:0005819 | spindle | 8.22e-02 | 1.00e+00 | 3.549 | 1 | 7 | 112 |
GO:0097190 | apoptotic signaling pathway | 8.29e-02 | 1.00e+00 | 3.536 | 1 | 6 | 113 |
GO:0044237 | cellular metabolic process | 8.57e-02 | 1.00e+00 | 3.486 | 1 | 5 | 117 |
GO:0006325 | chromatin organization | 8.64e-02 | 1.00e+00 | 3.474 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 8.85e-02 | 1.00e+00 | 3.438 | 1 | 9 | 121 |
GO:0030036 | actin cytoskeleton organization | 8.99e-02 | 1.00e+00 | 3.414 | 1 | 5 | 123 |
GO:0030027 | lamellipodium | 9.13e-02 | 1.00e+00 | 3.391 | 1 | 4 | 125 |
GO:0000790 | nuclear chromatin | 9.41e-02 | 1.00e+00 | 3.345 | 1 | 9 | 129 |
GO:0031982 | vesicle | 9.55e-02 | 1.00e+00 | 3.323 | 1 | 9 | 131 |
GO:0005634 | nucleus | 9.78e-02 | 1.00e+00 | 0.787 | 6 | 136 | 4559 |
GO:0000086 | G2/M transition of mitotic cell cycle | 9.90e-02 | 1.00e+00 | 3.269 | 1 | 9 | 136 |
GO:0006457 | protein folding | 1.04e-01 | 1.00e+00 | 3.197 | 1 | 7 | 143 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.08e-01 | 1.00e+00 | 3.137 | 1 | 32 | 149 |
GO:0005198 | structural molecule activity | 1.09e-01 | 1.00e+00 | 3.128 | 1 | 5 | 150 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 9 | 156 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 7 | 165 |
GO:0030424 | axon | 1.20e-01 | 1.00e+00 | 2.982 | 1 | 4 | 166 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.21e-01 | 1.00e+00 | 2.964 | 1 | 12 | 168 |
GO:0006886 | intracellular protein transport | 1.23e-01 | 1.00e+00 | 2.939 | 1 | 5 | 171 |
GO:0032403 | protein complex binding | 1.31e-01 | 1.00e+00 | 2.841 | 1 | 10 | 183 |
GO:0005737 | cytoplasm | 1.33e-01 | 1.00e+00 | 0.799 | 5 | 110 | 3767 |
GO:0003924 | GTPase activity | 1.40e-01 | 1.00e+00 | 2.735 | 1 | 12 | 197 |
GO:0030168 | platelet activation | 1.46e-01 | 1.00e+00 | 2.677 | 1 | 10 | 205 |
GO:0006184 | GTP catabolic process | 1.52e-01 | 1.00e+00 | 2.615 | 1 | 12 | 214 |
GO:0007067 | mitotic nuclear division | 1.60e-01 | 1.00e+00 | 2.530 | 1 | 14 | 227 |
GO:0005759 | mitochondrial matrix | 1.61e-01 | 1.00e+00 | 2.524 | 1 | 14 | 228 |
GO:0008380 | RNA splicing | 1.61e-01 | 1.00e+00 | 2.524 | 1 | 11 | 228 |
GO:0005739 | mitochondrion | 1.74e-01 | 1.00e+00 | 1.394 | 2 | 28 | 998 |
GO:0005975 | carbohydrate metabolic process | 1.77e-01 | 1.00e+00 | 2.374 | 1 | 9 | 253 |
GO:0004842 | ubiquitin-protein transferase activity | 1.78e-01 | 1.00e+00 | 2.362 | 1 | 6 | 255 |
GO:0043065 | positive regulation of apoptotic process | 1.86e-01 | 1.00e+00 | 2.291 | 1 | 10 | 268 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 1.87e-01 | 1.00e+00 | 2.285 | 1 | 15 | 269 |
GO:0006954 | inflammatory response | 1.92e-01 | 1.00e+00 | 2.243 | 1 | 7 | 277 |
GO:0007264 | small GTPase mediated signal transduction | 1.93e-01 | 1.00e+00 | 2.233 | 1 | 4 | 279 |
GO:0007186 | G-protein coupled receptor signaling pathway | 2.00e-01 | 1.00e+00 | 2.182 | 1 | 7 | 289 |
GO:0005856 | cytoskeleton | 2.01e-01 | 1.00e+00 | 2.172 | 1 | 12 | 291 |
GO:0016567 | protein ubiquitination | 2.03e-01 | 1.00e+00 | 2.152 | 1 | 5 | 295 |
GO:0030154 | cell differentiation | 2.07e-01 | 1.00e+00 | 2.123 | 1 | 5 | 301 |
GO:0035556 | intracellular signal transduction | 2.08e-01 | 1.00e+00 | 2.113 | 1 | 9 | 303 |
GO:0005525 | GTP binding | 2.13e-01 | 1.00e+00 | 2.081 | 1 | 12 | 310 |
GO:0008283 | cell proliferation | 2.24e-01 | 1.00e+00 | 1.999 | 1 | 14 | 328 |
GO:0044281 | small molecule metabolic process | 2.35e-01 | 1.00e+00 | 1.115 | 2 | 58 | 1211 |
GO:0000139 | Golgi membrane | 2.43e-01 | 1.00e+00 | 1.861 | 1 | 3 | 361 |
GO:0046982 | protein heterodimerization activity | 2.55e-01 | 1.00e+00 | 1.787 | 1 | 13 | 380 |
GO:0055114 | oxidation-reduction process | 2.78e-01 | 1.00e+00 | 1.642 | 1 | 12 | 420 |
GO:0043066 | negative regulation of apoptotic process | 2.80e-01 | 1.00e+00 | 1.629 | 1 | 31 | 424 |
GO:0005886 | plasma membrane | 3.13e-01 | 1.00e+00 | 0.607 | 3 | 45 | 2582 |
GO:0006915 | apoptotic process | 3.51e-01 | 1.00e+00 | 1.240 | 1 | 33 | 555 |
GO:0005730 | nucleolus | 3.61e-01 | 1.00e+00 | 0.676 | 2 | 69 | 1641 |
GO:0005615 | extracellular space | 5.30e-01 | 1.00e+00 | 0.454 | 1 | 17 | 957 |
GO:0006355 | regulation of transcription, DNA-templated | 5.45e-01 | 1.00e+00 | 0.395 | 1 | 18 | 997 |
GO:0008270 | zinc ion binding | 5.45e-01 | 1.00e+00 | 0.395 | 1 | 12 | 997 |
GO:0005524 | ATP binding | 6.46e-01 | 1.00e+00 | 0.015 | 1 | 60 | 1298 |