int-snw-54984

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.954	3.03e-16	1.64e-03	2.97e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-54984 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ PINX1 ]	54984	1	0.200	0.954	96	-	-
RSL24D1	51187	36	1.300	1.020	59	Yes	-
DDX18	8886	9	0.660	1.013	173	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
PFDN2	5202	2	0.837	0.955	43	Yes	-
SAP18	10284	8	1.115	1.069	57	Yes	-
FAU	2197	1	0.431	0.954	23	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
RPS3A	6189	11	0.835	1.069	166	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (19)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DDX18	8886	RSL24D1	51187	pp	--	int.I2D: YeastLow, BioGrid_Yeast
DDX18	8886	PINX1	54984	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	RPS3A	6189	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPS11	6205	PINX1	54984	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPS3A	6189	PINX1	54984	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid
RPS3A	6189	SAP18	10284	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, MINT; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
RPS3A	6189	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	DDX18	8886	pp	--	int.I2D: YeastLow
PSMD11	5717	DDX18	8886	pp	--	int.I2D: YeastLow
FAU	2197	PINX1	54984	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
PFDN2	5202	PINX1	54984	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPS3A	6189	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	DDX18	8886	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (150)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0019083	viral transcription	6.12e-09	8.83e-05	6.098	5	10	81
GO:0006415	translational termination	8.81e-09	1.27e-04	5.995	5	10	87
GO:0006414	translational elongation	1.24e-08	1.78e-04	5.898	5	13	93
GO:0016071	mRNA metabolic process	2.00e-08	2.89e-04	4.900	6	31	223
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.18e-08	3.14e-04	5.737	5	10	104
GO:0022627	cytosolic small ribosomal subunit	3.21e-08	4.62e-04	6.830	4	4	39
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.46e-08	4.98e-04	5.605	5	11	114
GO:0019058	viral life cycle	3.61e-08	5.21e-04	5.592	5	13	115
GO:0016070	RNA metabolic process	3.68e-08	5.31e-04	4.752	6	32	247
GO:0044267	cellular protein metabolic process	5.73e-08	8.26e-04	4.034	7	29	474
GO:0006413	translational initiation	6.95e-08	1.00e-03	5.404	5	17	131
GO:0003735	structural constituent of ribosome	8.70e-08	1.25e-03	5.340	5	10	137
GO:0006412	translation	1.15e-06	1.65e-02	4.592	5	20	230
GO:0016032	viral process	3.44e-06	4.96e-02	3.640	6	55	534
GO:0010467	gene expression	1.26e-05	1.82e-01	3.315	6	59	669
GO:0044822	poly(A) RNA binding	1.28e-05	1.85e-01	2.879	7	49	1056
GO:0070062	extracellular vesicular exosome	3.39e-04	1.00e+00	1.887	8	104	2400
GO:0005829	cytosol	4.48e-04	1.00e+00	1.830	8	132	2496
GO:0051084	'de novo' posttranslational protein folding	4.91e-04	1.00e+00	5.906	2	4	37
GO:0051972	regulation of telomerase activity	9.01e-04	1.00e+00	10.116	1	1	1
GO:0019521	D-gluconate metabolic process	9.01e-04	1.00e+00	10.116	1	1	1
GO:0070034	telomeric RNA binding	1.80e-03	1.00e+00	9.116	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.80e-03	1.00e+00	9.116	1	1	2
GO:0019322	pentose biosynthetic process	1.80e-03	1.00e+00	9.116	1	2	2
GO:0005055	laminin receptor activity	1.80e-03	1.00e+00	9.116	1	1	2
GO:0006407	rRNA export from nucleus	1.80e-03	1.00e+00	9.116	1	1	2
GO:0005730	nucleolus	1.81e-03	1.00e+00	2.020	6	69	1641
GO:0016020	membrane	2.06e-03	1.00e+00	1.986	6	90	1681
GO:0061574	ASAP complex	2.70e-03	1.00e+00	8.531	1	1	3
GO:0010521	telomerase inhibitor activity	2.70e-03	1.00e+00	8.531	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	2.70e-03	1.00e+00	8.531	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	2.70e-03	1.00e+00	8.531	1	1	3
GO:0003723	RNA binding	3.17e-03	1.00e+00	3.283	3	20	342
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.60e-03	1.00e+00	8.116	1	1	4
GO:0030686	90S preribosome	3.60e-03	1.00e+00	8.116	1	1	4
GO:0005925	focal adhesion	3.84e-03	1.00e+00	3.185	3	19	366
GO:0030529	ribonucleoprotein complex	4.41e-03	1.00e+00	4.308	2	8	112
GO:0043248	proteasome assembly	4.50e-03	1.00e+00	7.794	1	1	5
GO:0002181	cytoplasmic translation	5.40e-03	1.00e+00	7.531	1	1	6
GO:0030957	Tat protein binding	5.40e-03	1.00e+00	7.531	1	3	6
GO:0000028	ribosomal small subunit assembly	6.29e-03	1.00e+00	7.308	1	1	7
GO:0006457	protein folding	7.09e-03	1.00e+00	3.956	2	7	143
GO:0051974	negative regulation of telomerase activity	7.19e-03	1.00e+00	7.116	1	2	8
GO:0070688	MLL5-L complex	7.19e-03	1.00e+00	7.116	1	1	8
GO:0016272	prefoldin complex	8.09e-03	1.00e+00	6.946	1	1	9
GO:0006098	pentose-phosphate shunt	8.98e-03	1.00e+00	6.794	1	4	10
GO:0007004	telomere maintenance via telomerase	9.87e-03	1.00e+00	6.656	1	1	11
GO:0005838	proteasome regulatory particle	1.08e-02	1.00e+00	6.531	1	7	12
GO:0005515	protein binding	1.11e-02	1.00e+00	0.881	10	184	6024
GO:0042273	ribosomal large subunit biogenesis	1.17e-02	1.00e+00	6.415	1	4	13
GO:0007080	mitotic metaphase plate congression	1.17e-02	1.00e+00	6.415	1	2	13
GO:0035267	NuA4 histone acetyltransferase complex	1.26e-02	1.00e+00	6.308	1	4	14
GO:0048025	negative regulation of mRNA splicing, via spliceosome	1.34e-02	1.00e+00	6.209	1	1	15
GO:0050998	nitric-oxide synthase binding	1.43e-02	1.00e+00	6.116	1	1	16
GO:0019731	antibacterial humoral response	1.43e-02	1.00e+00	6.116	1	1	16
GO:0002227	innate immune response in mucosa	1.43e-02	1.00e+00	6.116	1	1	16
GO:0015935	small ribosomal subunit	1.52e-02	1.00e+00	6.028	1	1	17
GO:0022624	proteasome accessory complex	1.52e-02	1.00e+00	6.028	1	8	17
GO:0004004	ATP-dependent RNA helicase activity	1.61e-02	1.00e+00	5.946	1	2	18
GO:0035145	exon-exon junction complex	1.70e-02	1.00e+00	5.868	1	1	19
GO:0048863	stem cell differentiation	1.70e-02	1.00e+00	5.868	1	1	19
GO:0030863	cortical cytoskeleton	1.97e-02	1.00e+00	5.656	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.97e-02	1.00e+00	5.656	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	2.05e-02	1.00e+00	5.592	1	4	23
GO:0043236	laminin binding	2.05e-02	1.00e+00	5.592	1	1	23
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	2.32e-02	1.00e+00	5.415	1	1	26
GO:0019843	rRNA binding	2.41e-02	1.00e+00	5.361	1	3	27
GO:0043022	ribosome binding	2.41e-02	1.00e+00	5.361	1	3	27
GO:0050661	NADP binding	2.41e-02	1.00e+00	5.361	1	2	27
GO:0031492	nucleosomal DNA binding	2.41e-02	1.00e+00	5.361	1	4	27
GO:0000118	histone deacetylase complex	2.50e-02	1.00e+00	5.308	1	1	28
GO:0019894	kinesin binding	2.50e-02	1.00e+00	5.308	1	1	28
GO:0042254	ribosome biogenesis	2.67e-02	1.00e+00	5.209	1	1	30
GO:1903507	negative regulation of nucleic acid-templated transcription	2.85e-02	1.00e+00	5.116	1	2	32
GO:0000228	nuclear chromosome	2.94e-02	1.00e+00	5.071	1	1	33
GO:0001895	retina homeostasis	3.02e-02	1.00e+00	5.028	1	1	34
GO:0034332	adherens junction organization	3.20e-02	1.00e+00	4.946	1	1	36
GO:0070527	platelet aggregation	3.37e-02	1.00e+00	4.868	1	2	38
GO:0000781	chromosome, telomeric region	3.46e-02	1.00e+00	4.830	1	3	39
GO:0021762	substantia nigra development	3.90e-02	1.00e+00	4.656	1	2	44
GO:0050830	defense response to Gram-positive bacterium	3.98e-02	1.00e+00	4.624	1	2	45
GO:0022625	cytosolic large ribosomal subunit	4.33e-02	1.00e+00	4.501	1	6	49
GO:0006521	regulation of cellular amino acid metabolic process	4.42e-02	1.00e+00	4.472	1	17	50
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	4.68e-02	1.00e+00	4.388	1	5	53
GO:0045216	cell-cell junction organization	4.76e-02	1.00e+00	4.361	1	2	54
GO:0005840	ribosome	5.11e-02	1.00e+00	4.258	1	1	58
GO:0000502	proteasome complex	5.11e-02	1.00e+00	4.258	1	17	58
GO:0043066	negative regulation of apoptotic process	5.43e-02	1.00e+00	2.388	2	31	424
GO:0000776	kinetochore	5.53e-02	1.00e+00	4.138	1	4	63
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.62e-02	1.00e+00	4.116	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.71e-02	1.00e+00	4.093	1	22	65
GO:0034329	cell junction assembly	5.96e-02	1.00e+00	4.028	1	1	68
GO:0000777	condensed chromosome kinetochore	5.96e-02	1.00e+00	4.028	1	4	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.13e-02	1.00e+00	3.986	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.30e-02	1.00e+00	3.946	1	20	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	6.47e-02	1.00e+00	3.906	1	6	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.47e-02	1.00e+00	3.906	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.56e-02	1.00e+00	3.887	1	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.89e-02	1.00e+00	3.812	1	23	79
GO:0006928	cellular component movement	7.90e-02	1.00e+00	3.608	1	7	91
GO:0005200	structural constituent of cytoskeleton	7.90e-02	1.00e+00	3.608	1	8	91
GO:0001649	osteoblast differentiation	7.99e-02	1.00e+00	3.592	1	6	92
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.99e-02	1.00e+00	3.592	1	21	92
GO:0051082	unfolded protein binding	8.07e-02	1.00e+00	3.576	1	5	93
GO:0006364	rRNA processing	8.15e-02	1.00e+00	3.561	1	6	94
GO:0014069	postsynaptic density	9.07e-02	1.00e+00	3.401	1	3	105
GO:0072562	blood microparticle	9.56e-02	1.00e+00	3.321	1	3	111
GO:0005737	cytoplasm	9.60e-02	1.00e+00	0.821	6	110	3767
GO:0005819	spindle	9.64e-02	1.00e+00	3.308	1	7	112
GO:0000209	protein polyubiquitination	9.97e-02	1.00e+00	3.258	1	20	116
GO:0006325	chromatin organization	1.01e-01	1.00e+00	3.233	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	1.08e-01	1.00e+00	3.138	1	5	126
GO:0000790	nuclear chromatin	1.10e-01	1.00e+00	3.104	1	9	129
GO:0061024	membrane organization	1.23e-01	1.00e+00	2.936	1	7	145
GO:0000082	G1/S transition of mitotic cell cycle	1.26e-01	1.00e+00	2.896	1	32	149
GO:0042981	regulation of apoptotic process	1.27e-01	1.00e+00	2.887	1	24	150
GO:0006397	mRNA processing	1.35e-01	1.00e+00	2.794	1	2	160
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.39e-01	1.00e+00	2.749	1	7	165
GO:0030424	axon	1.40e-01	1.00e+00	2.741	1	4	166
GO:0016607	nuclear speck	1.44e-01	1.00e+00	2.689	1	3	172
GO:0034641	cellular nitrogen compound metabolic process	1.44e-01	1.00e+00	2.698	1	20	171
GO:0003714	transcription corepressor activity	1.49e-01	1.00e+00	2.640	1	8	178
GO:0008380	RNA splicing	1.87e-01	1.00e+00	2.283	1	11	228
GO:0005634	nucleus	2.00e-01	1.00e+00	0.546	6	136	4559
GO:0005975	carbohydrate metabolic process	2.06e-01	1.00e+00	2.133	1	9	253
GO:0005615	extracellular space	2.12e-01	1.00e+00	1.213	2	17	957
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.14e-01	1.00e+00	2.071	1	8	264
GO:0043065	positive regulation of apoptotic process	2.16e-01	1.00e+00	2.050	1	10	268
GO:0005575	cellular_component	2.24e-01	1.00e+00	1.992	1	1	279
GO:0005856	cytoskeleton	2.33e-01	1.00e+00	1.931	1	12	291
GO:0006200	ATP catabolic process	2.34e-01	1.00e+00	1.926	1	15	292
GO:0043234	protein complex	2.36e-01	1.00e+00	1.911	1	18	295
GO:0030154	cell differentiation	2.40e-01	1.00e+00	1.882	1	5	301
GO:0019901	protein kinase binding	2.51e-01	1.00e+00	1.807	1	21	317
GO:0007411	axon guidance	2.52e-01	1.00e+00	1.798	1	13	319
GO:0005654	nucleoplasm	2.55e-01	1.00e+00	1.036	2	76	1082
GO:0008285	negative regulation of cell proliferation	2.75e-01	1.00e+00	1.652	1	11	353
GO:0007155	cell adhesion	2.86e-01	1.00e+00	1.588	1	6	369
GO:0008150	biological_process	2.99e-01	1.00e+00	1.512	1	3	389
GO:0044281	small molecule metabolic process	2.99e-01	1.00e+00	0.874	2	58	1211
GO:0000278	mitotic cell cycle	3.01e-01	1.00e+00	1.505	1	48	391
GO:0055114	oxidation-reduction process	3.19e-01	1.00e+00	1.401	1	12	420
GO:0005524	ATP binding	3.29e-01	1.00e+00	0.774	2	60	1298
GO:0007596	blood coagulation	3.41e-01	1.00e+00	1.286	1	18	455
GO:0006915	apoptotic process	4.00e-01	1.00e+00	0.999	1	33	555
GO:0045087	innate immune response	4.22e-01	1.00e+00	0.896	1	24	596
GO:0005794	Golgi apparatus	4.30e-01	1.00e+00	0.863	1	15	610
GO:0005739	mitochondrion	6.06e-01	1.00e+00	0.153	1	28	998
GO:0006351	transcription, DNA-templated	7.47e-01	1.00e+00	-0.382	1	31	1446
GO:0005886	plasma membrane	9.23e-01	1.00e+00	-1.219	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-54984

Statistics

Genes (13)

Interactions (19)

Related GO terms (150)