int-snw-5243

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.924 4.18e-15 3.10e-03 4.71e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-5243 subnetwork

Genes (19)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RBX1 9978 971.1851.151139Yes-
PHB2 11331 90.8291.076140Yes-
PSMA2 5683 601.0931.10689Yes-
PSMB7 5695 480.9821.05257Yes-
PSMA1 5682 610.9961.052123Yes-
ATP6V1B2 526 440.8811.076278--
RPSA 3921 1561.3271.151152Yes-
PSMD2 5708 30.4630.961386Yes-
ACO2 50 501.0001.076191Yes-
EEF2 1938 270.8901.043301Yes-
PSMD3 5709 570.9861.106146Yes-
RPS11 6205 360.9931.113175Yes-
RPL14 9045 421.2501.113143Yes-
[ ABCB1 ] 5243 10.2220.92421Yes-
PSMB2 5690 180.8771.026117Yes-
RNF2 6045 20.4230.926106--
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
HSPD1 3329 350.9131.035286Yes-

Interactions (55)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA2 5683 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD2 5708 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMD2 5708 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMD2 5708 PHB2 11331 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HSPD1 3329 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD2 5708 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
PSMD2 5708 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, IntAct_Yeast, Krogan_Core, YeastLow
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
RPSA 3921 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
ABCB1 5243 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
RPS11 6205 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ABCB1 5243 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ABCB1 5243 RNF2 6045 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, IntAct, HPRD;
int.HPRD: in vivo, yeast 2-hybrid
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACO2 50 PSMD2 5708 pp -- int.I2D: YeastLow
EEF2 1938 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMD2 5708 RBX1 9978 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow
ABCB1 5243 PHB2 11331 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD2 5708 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastLow

Related GO terms (247)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016071mRNA metabolic process5.22e-147.53e-105.0891031223
GO:0016070RNA metabolic process1.46e-132.11e-094.9421032247
GO:0006521regulation of cellular amino acid metabolic process1.90e-132.73e-096.73271750
GO:0016032viral process2.34e-133.37e-094.0921255534
GO:0000502proteasome complex5.67e-138.18e-096.51871758
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.17e-121.68e-086.37671964
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.31e-121.89e-086.35372265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.24e-123.23e-086.24672270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.75e-123.97e-086.20672072
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.36e-124.84e-086.16672274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.70e-125.34e-086.14772075
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process5.39e-127.77e-086.07272379
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.61e-112.33e-075.85272192
GO:0000209protein polyubiquitination8.43e-111.22e-065.518720116
GO:0010467gene expression1.06e-101.53e-063.6421159669
GO:0070062extracellular vesicular exosome1.93e-102.79e-062.339161042400
GO:0000082G1/S transition of mitotic cell cycle4.95e-107.14e-065.156732149
GO:0042981regulation of apoptotic process5.19e-107.48e-065.147724150
GO:0034641cellular nitrogen compound metabolic process1.30e-091.88e-054.958720171
GO:0005839proteasome core complex6.50e-099.38e-057.3984818
GO:0005829cytosol6.93e-099.99e-052.190151322496
GO:0004298threonine-type endopeptidase activity8.23e-091.19e-047.3204819
GO:0000278mitotic cell cycle1.58e-082.28e-043.957848391
GO:0043066negative regulation of apoptotic process2.97e-084.29e-043.840831424
GO:0005654nucleoplasm2.68e-073.86e-032.81110761082
GO:0005838proteasome regulatory particle4.23e-076.10e-037.5683712
GO:0022624proteasome accessory complex1.30e-061.88e-027.0663817
GO:0016020membrane1.62e-062.33e-022.31211901681
GO:0006915apoptotic process4.05e-065.84e-023.259733555
GO:0006414translational elongation5.83e-068.41e-025.02941393
GO:0044281small molecule metabolic process8.57e-061.24e-012.4969581211
GO:0019773proteasome core complex, alpha-subunit complex4.58e-056.61e-017.568248
GO:0030234enzyme regulator activity1.27e-041.00e+006.8682313
GO:0019083viral transcription1.55e-041.00e+004.81331081
GO:0005515protein binding1.85e-041.00e+001.012161846024
GO:0006415translational termination1.92e-041.00e+004.71031087
GO:0042176regulation of protein catabolic process1.95e-041.00e+006.5682316
GO:0006412translation2.02e-041.00e+003.723420230
GO:0044267cellular protein metabolic process2.98e-041.00e+003.001529474
GO:0006614SRP-dependent cotranslational protein targeting to membrane3.24e-041.00e+004.453310104
GO:0005844polysome4.09e-041.00e+006.0452423
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay4.25e-041.00e+004.320311114
GO:0019058viral life cycle4.36e-041.00e+004.308313115
GO:0006413translational initiation6.38e-041.00e+004.120317131
GO:0003735structural constituent of ribosome7.27e-041.00e+004.055310137
GO:0022627cytosolic small ribosomal subunit1.18e-031.00e+005.2832439
GO:0002842positive regulation of T cell mediated immune response to tumor cell1.32e-031.00e+009.568111
GO:0036353histone H2A-K119 monoubiquitination1.32e-031.00e+009.568111
GO:0048291isotype switching to IgG isotypes1.32e-031.00e+009.568111
GO:0002368B cell cytokine production1.32e-031.00e+009.568111
GO:00515383 iron, 4 sulfur cluster binding2.63e-031.00e+008.568112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.63e-031.00e+008.568112
GO:0003994aconitate hydratase activity2.63e-031.00e+008.568112
GO:0005055laminin receptor activity2.63e-031.00e+008.568112
GO:0006407rRNA export from nucleus2.63e-031.00e+008.568112
GO:0006458'de novo' protein folding3.95e-031.00e+007.983113
GO:0008559xenobiotic-transporting ATPase activity3.95e-031.00e+007.983113
GO:0030135coated vesicle3.95e-031.00e+007.983113
GO:0071535RING-like zinc finger domain binding3.95e-031.00e+007.983113
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.26e-031.00e+007.568114
GO:003068690S preribosome5.26e-031.00e+007.568114
GO:0031467Cul7-RING ubiquitin ligase complex5.26e-031.00e+007.568114
GO:0019788NEDD8 ligase activity5.26e-031.00e+007.568114
GO:0043234protein complex6.44e-031.00e+002.949318295
GO:0031465Cul4B-RING E3 ubiquitin ligase complex6.57e-031.00e+007.246135
GO:0031461cullin-RING ubiquitin ligase complex6.57e-031.00e+007.246115
GO:0043248proteasome assembly6.57e-031.00e+007.246115
GO:0046696lipopolysaccharide receptor complex6.57e-031.00e+007.246115
GO:0006102isocitrate metabolic process6.57e-031.00e+007.246115
GO:0030891VCB complex6.57e-031.00e+007.246125
GO:0033600negative regulation of mammary gland epithelial cell proliferation6.57e-031.00e+007.246115
GO:0042908xenobiotic transport6.57e-031.00e+007.246115
GO:0003688DNA replication origin binding7.88e-031.00e+006.983126
GO:0000791euchromatin7.88e-031.00e+006.983116
GO:0030957Tat protein binding7.88e-031.00e+006.983136
GO:0060744mammary gland branching involved in thelarche7.88e-031.00e+006.983116
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex7.88e-031.00e+006.983116
GO:0006101citrate metabolic process7.88e-031.00e+006.983116
GO:0060762regulation of branching involved in mammary gland duct morphogenesis7.88e-031.00e+006.983116
GO:0031466Cul5-RING ubiquitin ligase complex7.88e-031.00e+006.983116
GO:0033180proton-transporting V-type ATPase, V1 domain9.19e-031.00e+006.761127
GO:0072089stem cell proliferation9.19e-031.00e+006.761117
GO:0000028ribosomal small subunit assembly9.19e-031.00e+006.761117
GO:0001739sex chromatin9.19e-031.00e+006.761117
GO:0031462Cul2-RING ubiquitin ligase complex9.19e-031.00e+006.761127
GO:0030529ribonucleoprotein complex9.38e-031.00e+003.76128112
GO:0044822poly(A) RNA binding1.02e-021.00e+001.8465491056
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.05e-021.00e+006.568128
GO:0070688MLL5-L complex1.05e-021.00e+006.568118
GO:0045116protein neddylation1.05e-021.00e+006.568128
GO:0051604protein maturation1.05e-021.00e+006.568118
GO:0008494translation activator activity1.18e-021.00e+006.398119
GO:0006855drug transmembrane transport1.31e-021.00e+006.2461110
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway1.31e-021.00e+006.2461110
GO:0043032positive regulation of macrophage activation1.31e-021.00e+006.2461110
GO:0032727positive regulation of interferon-alpha production1.44e-021.00e+006.1091111
GO:0035518histone H2A monoubiquitination1.44e-021.00e+006.1091311
GO:0035102PRC1 complex1.57e-021.00e+005.9831112
GO:0005634nucleus1.59e-021.00e+000.873111364559
GO:0042273ribosomal large subunit biogenesis1.70e-021.00e+005.8681413
GO:0001530lipopolysaccharide binding1.70e-021.00e+005.8681313
GO:0051131chaperone-mediated protein complex assembly1.70e-021.00e+005.8681113
GO:0035267NuA4 histone acetyltransferase complex1.83e-021.00e+005.7611414
GO:0009948anterior/posterior axis specification1.83e-021.00e+005.7611214
GO:0046961proton-transporting ATPase activity, rotational mechanism1.96e-021.00e+005.6611315
GO:0060749mammary gland alveolus development1.96e-021.00e+005.6611215
GO:0042026protein refolding1.96e-021.00e+005.6611215
GO:0046034ATP metabolic process1.96e-021.00e+005.6611115
GO:0050998nitric-oxide synthase binding2.09e-021.00e+005.5681116
GO:0010243response to organonitrogen compound2.22e-021.00e+005.4811317
GO:0050870positive regulation of T cell activation2.22e-021.00e+005.4811117
GO:0003746translation elongation factor activity2.22e-021.00e+005.4811317
GO:0015078hydrogen ion transmembrane transporter activity2.48e-021.00e+005.3201319
GO:0032733positive regulation of interleukin-10 production2.48e-021.00e+005.3201119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.48e-021.00e+005.3201119
GO:0048863stem cell differentiation2.48e-021.00e+005.3201119
GO:0042100B cell proliferation2.73e-021.00e+005.1761121
GO:0001702gastrulation with mouth forming second2.73e-021.00e+005.1761221
GO:0030863cortical cytoskeleton2.86e-021.00e+005.1091122
GO:0036464cytoplasmic ribonucleoprotein granule2.86e-021.00e+005.1091422
GO:0043044ATP-dependent chromatin remodeling2.99e-021.00e+005.0451423
GO:0031463Cul3-RING ubiquitin ligase complex2.99e-021.00e+005.0451323
GO:0043236laminin binding2.99e-021.00e+005.0451123
GO:0006513protein monoubiquitination2.99e-021.00e+005.0451123
GO:0042113B cell activation3.24e-021.00e+004.9241225
GO:0032735positive regulation of interleukin-12 production3.24e-021.00e+004.9241125
GO:0031519PcG protein complex3.24e-021.00e+004.9241425
GO:0015991ATP hydrolysis coupled proton transport3.37e-021.00e+004.8681426
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia3.37e-021.00e+004.8681326
GO:0042626ATPase activity, coupled to transmembrane movement of substances3.37e-021.00e+004.8681126
GO:0030331estrogen receptor binding3.50e-021.00e+004.8131227
GO:0019843rRNA binding3.50e-021.00e+004.8131327
GO:0043022ribosome binding3.50e-021.00e+004.8131327
GO:0071339MLL1 complex3.50e-021.00e+004.8131327
GO:0031492nucleosomal DNA binding3.50e-021.00e+004.8131427
GO:0005759mitochondrial matrix3.57e-021.00e+002.735214228
GO:0006099tricarboxylic acid cycle3.63e-021.00e+004.7611428
GO:0019894kinesin binding3.63e-021.00e+004.7611128
GO:0019005SCF ubiquitin ligase complex3.75e-021.00e+004.7101129
GO:0015992proton transport3.75e-021.00e+004.7101329
GO:0033572transferrin transport3.88e-021.00e+004.6611530
GO:0016604nuclear body4.01e-021.00e+004.6141231
GO:0051701interaction with host4.13e-021.00e+004.5681432
GO:0004842ubiquitin-protein transferase activity4.37e-021.00e+002.57426255
GO:0001895retina homeostasis4.39e-021.00e+004.4811134
GO:00515394 iron, 4 sulfur cluster binding4.51e-021.00e+004.4391335
GO:0034332adherens junction organization4.64e-021.00e+004.3981136
GO:0032755positive regulation of interleukin-6 production4.64e-021.00e+004.3981236
GO:0090382phagosome maturation4.64e-021.00e+004.3981536
GO:0051084'de novo' posttranslational protein folding4.77e-021.00e+004.3591437
GO:0005902microvillus4.89e-021.00e+004.3201238
GO:0070527platelet aggregation4.89e-021.00e+004.3201238
GO:0032729positive regulation of interferon-gamma production5.02e-021.00e+004.2831239
GO:0005743mitochondrial inner membrane5.07e-021.00e+002.45428277
GO:0042110T cell activation5.39e-021.00e+004.1761342
GO:0014070response to organic cyclic compound5.52e-021.00e+004.1421443
GO:0006200ATP catabolic process5.57e-021.00e+002.378215292
GO:0021762substantia nigra development5.64e-021.00e+004.1091244
GO:0045727positive regulation of translation5.64e-021.00e+004.1091344
GO:0005730nucleolus5.66e-021.00e+001.2105691641
GO:0022625cytosolic large ribosomal subunit6.27e-021.00e+003.9531649
GO:0006091generation of precursor metabolites and energy6.39e-021.00e+003.9241350
GO:0006986response to unfolded protein6.39e-021.00e+003.9241250
GO:0005905coated pit6.39e-021.00e+003.9241350
GO:0019901protein kinase binding6.44e-021.00e+002.260221317
GO:0006879cellular iron ion homeostasis6.51e-021.00e+003.8961451
GO:0003725double-stranded RNA binding6.64e-021.00e+003.8681552
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.76e-021.00e+003.8401553
GO:0002244hematopoietic progenitor cell differentiation6.88e-021.00e+003.8131154
GO:0045216cell-cell junction organization6.88e-021.00e+003.8131254
GO:0000932cytoplasmic mRNA processing body6.88e-021.00e+003.8131354
GO:0002039p53 binding7.01e-021.00e+003.7871755
GO:0012505endomembrane system7.13e-021.00e+003.7611256
GO:0003723RNA binding7.36e-021.00e+002.150220342
GO:0005840ribosome7.37e-021.00e+003.7101158
GO:0051087chaperone binding7.50e-021.00e+003.6861659
GO:0030141secretory granule7.86e-021.00e+003.6141262
GO:0000151ubiquitin ligase complex7.99e-021.00e+003.5911163
GO:0005925focal adhesion8.27e-021.00e+002.052219366
GO:0005524ATP binding8.51e-021.00e+001.2264601298
GO:0034329cell junction assembly8.59e-021.00e+003.4811168
GO:0003697single-stranded DNA binding8.59e-021.00e+003.4811568
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis9.32e-021.00e+003.3591674
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process9.44e-021.00e+003.3391275
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process9.68e-021.00e+003.3011777
GO:0009986cell surface9.71e-021.00e+001.917211402
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.00e-011.00e+003.2461380
GO:0001726ruffle1.00e-011.00e+003.2461480
GO:0050821protein stabilization1.10e-011.00e+003.1091288
GO:0055085transmembrane transport1.11e-011.00e+001.803210435
GO:0042470melanosome1.13e-011.00e+003.0601991
GO:0016363nuclear matrix1.13e-011.00e+003.06011291
GO:0006928cellular component movement1.13e-011.00e+003.0601791
GO:0005200structural constituent of cytoskeleton1.13e-011.00e+003.0601891
GO:0001649osteoblast differentiation1.15e-011.00e+003.0451692
GO:0071456cellular response to hypoxia1.15e-011.00e+003.0451692
GO:0051082unfolded protein binding1.16e-011.00e+003.0291593
GO:0006364rRNA processing1.17e-011.00e+003.0141694
GO:0014069postsynaptic density1.30e-011.00e+002.85413105
GO:0005506iron ion binding1.30e-011.00e+002.85414105
GO:0015630microtubule cytoskeleton1.35e-011.00e+002.78714110
GO:0072562blood microparticle1.37e-011.00e+002.77413111
GO:0005739mitochondrion1.40e-011.00e+001.190328998
GO:0044237cellular metabolic process1.43e-011.00e+002.69815117
GO:0006325chromatin organization1.45e-011.00e+002.68615118
GO:0007219Notch signaling pathway1.47e-011.00e+002.66115120
GO:0006511ubiquitin-dependent protein catabolic process1.54e-011.00e+002.59115126
GO:0009615response to virus1.54e-011.00e+002.59115126
GO:0000790nuclear chromatin1.57e-011.00e+002.55719129
GO:0005215transporter activity1.58e-011.00e+002.54612130
GO:0000086G2/M transition of mitotic cell cycle1.65e-011.00e+002.48119136
GO:0016887ATPase activity1.69e-011.00e+002.43917140
GO:0008286insulin receptor signaling pathway1.71e-011.00e+002.41817142
GO:0006457protein folding1.73e-011.00e+002.40817143
GO:0061024membrane organization1.75e-011.00e+002.38817145
GO:0010628positive regulation of gene expression1.76e-011.00e+002.37815146
GO:0005769early endosome1.82e-011.00e+002.32012152
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.96e-011.00e+002.20217165
GO:0030424axon1.98e-011.00e+002.19314166
GO:0031625ubiquitin protein ligase binding2.10e-011.00e+002.092114178
GO:0032403protein complex binding2.16e-011.00e+002.052110183
GO:0003924GTPase activity2.30e-011.00e+001.946112197
GO:0005765lysosomal membrane2.36e-011.00e+001.90315203
GO:0006184GTP catabolic process2.47e-011.00e+001.827112214
GO:0016874ligase activity2.47e-011.00e+001.82711214
GO:0006810transport2.75e-011.00e+001.64911242
GO:0006281DNA repair2.93e-011.00e+001.540118261
GO:0043065positive regulation of apoptotic process3.00e-011.00e+001.502110268
GO:0042493response to drug3.15e-011.00e+001.418113284
GO:0005856cytoskeleton3.21e-011.00e+001.383112291
GO:0016567protein ubiquitination3.25e-011.00e+001.36415295
GO:0005525GTP binding3.38e-011.00e+001.292112310
GO:0043231intracellular membrane-bounded organelle3.45e-011.00e+001.25519318
GO:0007411axon guidance3.46e-011.00e+001.251113319
GO:0003682chromatin binding3.53e-011.00e+001.215111327
GO:0005813centrosome3.53e-011.00e+001.219114326
GO:0005615extracellular space3.62e-011.00e+000.666217957
GO:0008270zinc ion binding3.82e-011.00e+000.607212997
GO:0007155cell adhesion3.89e-011.00e+001.04116369
GO:0045892negative regulation of transcription, DNA-templated4.24e-011.00e+000.878115413
GO:0005886plasma membrane4.50e-011.00e+000.2344452582
GO:0007596blood coagulation4.56e-011.00e+000.738118455
GO:0000122negative regulation of transcription from RNA polymerase II promoter5.35e-011.00e+000.413116570
GO:0045087innate immune response5.52e-011.00e+000.349124596
GO:0005737cytoplasm5.79e-011.00e+000.01151103767
GO:0006351transcription, DNA-templated5.81e-011.00e+000.0702311446
GO:0016021integral component of membrane7.57e-011.00e+00-0.3852271982