Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.933 | 1.93e-15 | 2.57e-03 | 4.12e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PHB2 | 11331 | 9 | 0.829 | 1.076 | 140 | Yes | - |
PAFAH1B1 | 5048 | 6 | 0.691 | 1.076 | 71 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
[ KIF11 ] | 3832 | 1 | 0.278 | 0.933 | 33 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
DCTN1 | 1639 | 2 | 0.423 | 0.933 | 86 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | PAFAH1B1 | 5048 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
DCTN1 | 1639 | PAFAH1B1 | 5048 | pp | -- | int.I2D: BioGrid_Fly, BCI, BioGrid, HPRD; int.HPRD: in vivo |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PHB2 | 11331 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
DCTN1 | 1639 | KIF11 | 3832 | pp | -- | int.I2D: BioGrid, BCI, HPRD; int.HPRD: in vitro, in vivo, yeast 2-hybrid |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PAFAH1B1 | 5048 | PHB2 | 11331 | pp | -- | int.I2D: BioGrid_Yeast |
RPSA | 3921 | PHB2 | 11331 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0000278 | mitotic cell cycle | 7.19e-09 | 1.04e-04 | 4.427 | 7 | 48 | 391 |
GO:0006521 | regulation of cellular amino acid metabolic process | 6.20e-08 | 8.94e-04 | 6.587 | 4 | 17 | 50 |
GO:0000082 | G1/S transition of mitotic cell cycle | 8.22e-08 | 1.19e-03 | 5.334 | 5 | 32 | 149 |
GO:0000502 | proteasome complex | 1.14e-07 | 1.64e-03 | 6.373 | 4 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.70e-07 | 2.45e-03 | 6.231 | 4 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.81e-07 | 2.61e-03 | 6.209 | 4 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.45e-07 | 3.53e-03 | 6.102 | 4 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 2.74e-07 | 3.95e-03 | 6.061 | 4 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.06e-07 | 4.42e-03 | 6.022 | 4 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 3.23e-07 | 4.67e-03 | 6.002 | 4 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.99e-07 | 5.76e-03 | 5.927 | 4 | 23 | 79 |
GO:0016071 | mRNA metabolic process | 6.13e-07 | 8.84e-03 | 4.752 | 5 | 31 | 223 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 7.38e-07 | 1.06e-02 | 5.708 | 4 | 21 | 92 |
GO:0016070 | RNA metabolic process | 1.02e-06 | 1.46e-02 | 4.605 | 5 | 32 | 247 |
GO:0005829 | cytosol | 1.11e-06 | 1.61e-02 | 2.268 | 10 | 132 | 2496 |
GO:0000209 | protein polyubiquitination | 1.87e-06 | 2.70e-02 | 5.373 | 4 | 20 | 116 |
GO:0016032 | viral process | 1.91e-06 | 2.76e-02 | 3.755 | 6 | 55 | 534 |
GO:0042981 | regulation of apoptotic process | 5.21e-06 | 7.52e-02 | 5.002 | 4 | 24 | 150 |
GO:0005654 | nucleoplasm | 7.43e-06 | 1.07e-01 | 2.959 | 7 | 76 | 1082 |
GO:0034641 | cellular nitrogen compound metabolic process | 8.77e-06 | 1.26e-01 | 4.813 | 4 | 20 | 171 |
GO:0045502 | dynein binding | 3.48e-05 | 5.01e-01 | 7.772 | 2 | 2 | 11 |
GO:0005838 | proteasome regulatory particle | 4.17e-05 | 6.01e-01 | 7.646 | 2 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 8.57e-05 | 1.00e+00 | 7.144 | 2 | 8 | 17 |
GO:0005839 | proteasome core complex | 9.64e-05 | 1.00e+00 | 7.061 | 2 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 1.08e-04 | 1.00e+00 | 6.983 | 2 | 8 | 19 |
GO:0010467 | gene expression | 1.28e-04 | 1.00e+00 | 3.167 | 5 | 59 | 669 |
GO:0070062 | extracellular vesicular exosome | 1.53e-04 | 1.00e+00 | 2.002 | 8 | 104 | 2400 |
GO:0031252 | cell leading edge | 2.37e-04 | 1.00e+00 | 6.424 | 2 | 4 | 28 |
GO:0043066 | negative regulation of apoptotic process | 3.02e-04 | 1.00e+00 | 3.503 | 4 | 31 | 424 |
GO:0005871 | kinesin complex | 5.89e-04 | 1.00e+00 | 5.772 | 2 | 3 | 44 |
GO:0007067 | mitotic nuclear division | 7.62e-04 | 1.00e+00 | 3.990 | 3 | 14 | 227 |
GO:0000235 | astral microtubule | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0010970 | microtubule-based transport | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0051660 | establishment of centrosome localization | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0046469 | platelet activating factor metabolic process | 8.32e-04 | 1.00e+00 | 10.231 | 1 | 1 | 1 |
GO:0006915 | apoptotic process | 8.39e-04 | 1.00e+00 | 3.115 | 4 | 33 | 555 |
GO:0000776 | kinetochore | 1.20e-03 | 1.00e+00 | 5.254 | 2 | 4 | 63 |
GO:0016020 | membrane | 1.23e-03 | 1.00e+00 | 2.101 | 6 | 90 | 1681 |
GO:0051081 | nuclear envelope disassembly | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 2 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0021540 | corpus callosum morphogenesis | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 |
GO:0036035 | osteoclast development | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 2 | 2 |
GO:0005813 | centrosome | 2.16e-03 | 1.00e+00 | 3.467 | 3 | 14 | 326 |
GO:0000922 | spindle pole | 2.28e-03 | 1.00e+00 | 4.788 | 2 | 2 | 87 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 2.44e-03 | 1.00e+00 | 4.739 | 2 | 7 | 90 |
GO:0045505 | dynein intermediate chain binding | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 |
GO:0007100 | mitotic centrosome separation | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 2 | 4 |
GO:0005515 | protein binding | 4.10e-03 | 1.00e+00 | 0.997 | 10 | 184 | 6024 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 2 | 5 |
GO:0033600 | negative regulation of mammary gland epithelial cell proliferation | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0000730 | DNA recombinase assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0031023 | microtubule organizing center organization | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 |
GO:0008090 | retrograde axon cargo transport | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 6 |
GO:0007097 | nuclear migration | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 |
GO:0034452 | dynactin binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0060744 | mammary gland branching involved in thelarche | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0001667 | ameboidal-type cell migration | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 |
GO:0000086 | G2/M transition of mitotic cell cycle | 5.48e-03 | 1.00e+00 | 4.144 | 2 | 9 | 136 |
GO:0001961 | positive regulation of cytokine-mediated signaling pathway | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0000028 | ribosomal small subunit assembly | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0017145 | stem cell division | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 7 |
GO:0044267 | cellular protein metabolic process | 6.22e-03 | 1.00e+00 | 2.927 | 3 | 29 | 474 |
GO:0008017 | microtubule binding | 6.37e-03 | 1.00e+00 | 4.031 | 2 | 6 | 147 |
GO:0031512 | motile primary cilium | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 4 | 8 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0005869 | dynactin complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 |
GO:0032319 | regulation of Rho GTPase activity | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 9 |
GO:0021895 | cerebral cortex neuron differentiation | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 |
GO:0030424 | axon | 8.06e-03 | 1.00e+00 | 3.856 | 2 | 4 | 166 |
GO:0090307 | spindle assembly involved in mitosis | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0001675 | acrosome assembly | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 |
GO:0007051 | spindle organization | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 |
GO:0030286 | dynein complex | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 4 | 11 |
GO:0021819 | layer formation in cerebral cortex | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 |
GO:0031625 | ubiquitin protein ligase binding | 9.22e-03 | 1.00e+00 | 3.755 | 2 | 14 | 178 |
GO:0032403 | protein complex binding | 9.72e-03 | 1.00e+00 | 3.715 | 2 | 10 | 183 |
GO:0047496 | vesicle transport along microtubule | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 2 | 12 |
GO:0005662 | DNA replication factor A complex | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 3 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 4 | 14 |
GO:0019226 | transmission of nerve impulse | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 14 |
GO:0030904 | retromer complex | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 15 |
GO:0048854 | brain morphogenesis | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 15 |
GO:0060749 | mammary gland alveolus development | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 15 |
GO:0008574 | plus-end-directed microtubule motor activity | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0007405 | neuroblast proliferation | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0043274 | phospholipase binding | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 3 | 16 |
GO:0000132 | establishment of mitotic spindle orientation | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 |
GO:0044281 | small molecule metabolic process | 1.42e-02 | 1.00e+00 | 1.989 | 4 | 58 | 1211 |
GO:0045773 | positive regulation of axon extension | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 4 | 18 |
GO:0035861 | site of double-strand break | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 |
GO:0009306 | protein secretion | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 20 |
GO:0006298 | mismatch repair | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 20 |
GO:0032402 | melanosome transport | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 20 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 5 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 4 | 21 |
GO:0005874 | microtubule | 1.75e-02 | 1.00e+00 | 3.271 | 2 | 7 | 249 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 4 | 22 |
GO:0007052 | mitotic spindle organization | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 2 | 22 |
GO:0046329 | negative regulation of JNK cascade | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 |
GO:0005844 | polysome | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 |
GO:0006281 | DNA repair | 1.91e-02 | 1.00e+00 | 3.203 | 2 | 18 | 261 |
GO:0000722 | telomere maintenance via recombination | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 5 | 25 |
GO:0045931 | positive regulation of mitotic cell cycle | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 1 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 3 | 26 |
GO:0030331 | estrogen receptor binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 2 | 27 |
GO:0007017 | microtubule-based process | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 3 | 27 |
GO:0043022 | ribosome binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 4 | 27 |
GO:0010977 | negative regulation of neuron projection development | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 28 |
GO:0005875 | microtubule associated complex | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 2 | 28 |
GO:0019894 | kinesin binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.39e-02 | 1.00e+00 | 5.373 | 1 | 1 | 29 |
GO:0043234 | protein complex | 2.40e-02 | 1.00e+00 | 3.027 | 2 | 18 | 295 |
GO:0006271 | DNA strand elongation involved in DNA replication | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 7 | 30 |
GO:0051219 | phosphoprotein binding | 2.63e-02 | 1.00e+00 | 5.231 | 1 | 2 | 32 |
GO:0019901 | protein kinase binding | 2.75e-02 | 1.00e+00 | 2.923 | 2 | 21 | 317 |
GO:0001895 | retina homeostasis | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 1 | 34 |
GO:0007611 | learning or memory | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 34 |
GO:0005876 | spindle microtubule | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 2 | 34 |
GO:0034332 | adherens junction organization | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 3 | 37 |
GO:0021766 | hippocampus development | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 4 | 38 |
GO:0070527 | platelet aggregation | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 4 | 39 |
GO:0000781 | chromosome, telomeric region | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 3 | 39 |
GO:0050885 | neuromuscular process controlling balance | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 1 | 40 |
GO:0042147 | retrograde transport, endosome to Golgi | 3.36e-02 | 1.00e+00 | 4.874 | 1 | 3 | 41 |
GO:0021987 | cerebral cortex development | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 3 | 42 |
GO:0003774 | motor activity | 3.52e-02 | 1.00e+00 | 4.805 | 1 | 2 | 43 |
GO:0021762 | substantia nigra development | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 44 |
GO:0008344 | adult locomotory behavior | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 1 | 44 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.76e-02 | 1.00e+00 | 4.708 | 1 | 7 | 46 |
GO:0005730 | nucleolus | 3.91e-02 | 1.00e+00 | 1.551 | 4 | 69 | 1641 |
GO:0016042 | lipid catabolic process | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 48 |
GO:0003684 | damaged DNA binding | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 7 | 49 |
GO:0000226 | microtubule cytoskeleton organization | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 3 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 2 | 54 |
GO:0000724 | double-strand break repair via homologous recombination | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 3 | 55 |
GO:0000723 | telomere maintenance | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 6 | 56 |
GO:0007018 | microtubule-based movement | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 1 | 57 |
GO:0003777 | microtubule motor activity | 4.72e-02 | 1.00e+00 | 4.373 | 1 | 1 | 58 |
GO:0006987 | activation of signaling protein activity involved in unfolded protein response | 4.96e-02 | 1.00e+00 | 4.300 | 1 | 3 | 61 |
GO:0019903 | protein phosphatase binding | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0007059 | chromosome segregation | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 |
GO:0005634 | nucleus | 5.06e-02 | 1.00e+00 | 0.884 | 7 | 136 | 4559 |
GO:0007596 | blood coagulation | 5.32e-02 | 1.00e+00 | 2.401 | 2 | 18 | 455 |
GO:0006289 | nucleotide-excision repair | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 11 | 68 |
GO:0034329 | cell junction assembly | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 5 | 68 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 2 | 75 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 6.38e-02 | 1.00e+00 | 3.927 | 1 | 4 | 79 |
GO:0019083 | viral transcription | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 10 | 81 |
GO:0047485 | protein N-terminus binding | 6.93e-02 | 1.00e+00 | 3.805 | 1 | 5 | 86 |
GO:0006415 | translational termination | 7.01e-02 | 1.00e+00 | 3.788 | 1 | 10 | 87 |
GO:0016605 | PML body | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 3 | 88 |
GO:0016363 | nuclear matrix | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 12 | 91 |
GO:0006928 | cellular component movement | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 8 | 91 |
GO:0071456 | cellular response to hypoxia | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 6 | 92 |
GO:0006414 | translational elongation | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 13 | 93 |
GO:0001764 | neuron migration | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 3 | 93 |
GO:0030426 | growth cone | 7.70e-02 | 1.00e+00 | 3.646 | 1 | 5 | 96 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 10 | 104 |
GO:0005938 | cell cortex | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 3 | 104 |
GO:0014069 | postsynaptic density | 8.40e-02 | 1.00e+00 | 3.517 | 1 | 3 | 105 |
GO:0015630 | microtubule cytoskeleton | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 8.86e-02 | 1.00e+00 | 3.437 | 1 | 3 | 111 |
GO:0030529 | ribonucleoprotein complex | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 8 | 112 |
GO:0005819 | spindle | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 7 | 112 |
GO:0005635 | nuclear envelope | 9.01e-02 | 1.00e+00 | 3.411 | 1 | 6 | 113 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 9.09e-02 | 1.00e+00 | 3.398 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 13 | 115 |
GO:0006325 | chromatin organization | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 9.54e-02 | 1.00e+00 | 3.324 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 9.62e-02 | 1.00e+00 | 3.312 | 1 | 9 | 121 |
GO:0008201 | heparin binding | 9.69e-02 | 1.00e+00 | 3.300 | 1 | 4 | 122 |
GO:0030036 | actin cytoskeleton organization | 9.77e-02 | 1.00e+00 | 3.289 | 1 | 5 | 123 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.00e-01 | 1.00e+00 | 3.254 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 9 | 129 |
GO:0006413 | translational initiation | 1.04e-01 | 1.00e+00 | 3.198 | 1 | 17 | 131 |
GO:0003735 | structural constituent of ribosome | 1.08e-01 | 1.00e+00 | 3.133 | 1 | 10 | 137 |
GO:0016887 | ATPase activity | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 7 | 140 |
GO:0006457 | protein folding | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.14e-01 | 1.00e+00 | 3.051 | 1 | 7 | 145 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 7 | 165 |
GO:0031965 | nuclear membrane | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 3 | 168 |
GO:0006412 | translation | 1.75e-01 | 1.00e+00 | 2.386 | 1 | 20 | 230 |
GO:0007399 | nervous system development | 1.76e-01 | 1.00e+00 | 2.379 | 1 | 5 | 231 |
GO:0005737 | cytoplasm | 1.81e-01 | 1.00e+00 | 0.674 | 5 | 110 | 3767 |
GO:0043025 | neuronal cell body | 1.86e-01 | 1.00e+00 | 2.294 | 1 | 9 | 245 |
GO:0004842 | ubiquitin-protein transferase activity | 1.93e-01 | 1.00e+00 | 2.237 | 1 | 6 | 255 |
GO:0008152 | metabolic process | 1.95e-01 | 1.00e+00 | 2.220 | 1 | 3 | 258 |
GO:0005743 | mitochondrial inner membrane | 2.08e-01 | 1.00e+00 | 2.117 | 1 | 8 | 277 |
GO:0019899 | enzyme binding | 2.08e-01 | 1.00e+00 | 2.117 | 1 | 12 | 277 |
GO:0005856 | cytoskeleton | 2.17e-01 | 1.00e+00 | 2.046 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 2.18e-01 | 1.00e+00 | 2.041 | 1 | 15 | 292 |
GO:0016567 | protein ubiquitination | 2.20e-01 | 1.00e+00 | 2.027 | 1 | 5 | 295 |
GO:0007411 | axon guidance | 2.35e-01 | 1.00e+00 | 1.914 | 1 | 13 | 319 |
GO:0007268 | synaptic transmission | 2.44e-01 | 1.00e+00 | 1.856 | 1 | 6 | 332 |
GO:0003723 | RNA binding | 2.50e-01 | 1.00e+00 | 1.813 | 1 | 20 | 342 |
GO:0005925 | focal adhesion | 2.65e-01 | 1.00e+00 | 1.715 | 1 | 19 | 366 |
GO:0007155 | cell adhesion | 2.67e-01 | 1.00e+00 | 1.704 | 1 | 6 | 369 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.94e-01 | 1.00e+00 | 1.541 | 1 | 15 | 413 |
GO:0005524 | ATP binding | 2.95e-01 | 1.00e+00 | 0.889 | 2 | 60 | 1298 |
GO:0048471 | perinuclear region of cytoplasm | 3.46e-01 | 1.00e+00 | 1.260 | 1 | 13 | 502 |
GO:0042803 | protein homodimerization activity | 3.97e-01 | 1.00e+00 | 1.014 | 1 | 12 | 595 |
GO:0045087 | innate immune response | 3.97e-01 | 1.00e+00 | 1.012 | 1 | 24 | 596 |
GO:0005615 | extracellular space | 5.61e-01 | 1.00e+00 | 0.329 | 1 | 17 | 957 |
GO:0005739 | mitochondrion | 5.77e-01 | 1.00e+00 | 0.268 | 1 | 28 | 998 |
GO:0008270 | zinc ion binding | 5.77e-01 | 1.00e+00 | 0.270 | 1 | 12 | 997 |
GO:0044822 | poly(A) RNA binding | 5.99e-01 | 1.00e+00 | 0.187 | 1 | 49 | 1056 |
GO:0006351 | transcription, DNA-templated | 7.19e-01 | 1.00e+00 | -0.267 | 1 | 31 | 1446 |
GO:0005886 | plasma membrane | 9.06e-01 | 1.00e+00 | -1.103 | 1 | 45 | 2582 |