| Dataset | Score | p-value 1 | p-value 2 | p-value 3 | 
|---|---|---|---|---|
| wolf-screen-ratio-mammosphere-adherent | 0.979 | 2.87e-17 | 9.10e-04 | 1.92e-02 | 

| Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI | 
|---|---|---|---|---|---|---|---|
| RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - | 
| PSMD1 | 5707 | 12 | 0.836 | 1.057 | 113 | Yes | - | 
| RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - | 
| PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - | 
| PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - | 
| [ FPR1 ] | 2357 | 1 | -0.332 | 0.979 | 7 | - | Yes | 
| PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - | 
| PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - | 
| PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - | 
| ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - | 
| GNAI2 | 2771 | 3 | -0.516 | 1.057 | 98 | - | Yes | 
| RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - | 
| Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources | 
|---|---|---|---|---|---|---|
| PSMD1 | 5707 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core | 
| RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast | 
| GNAI2 | 2771 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast | 
| ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct | 
| PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow | 
| PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow | 
| ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct | 
| PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium | 
| PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG | 
| FPR1 | 2357 | GNAI2 | 2771 | pp | -- | int.I2D: HPRD; int.HPRD: in vivo | 
| ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast | 
| PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid | 
| PSMD1 | 5707 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast | 
| ACTB | 60 | GNAI2 | 2771 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct | 
| PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast | 
| PSMA1 | 5682 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast | 
| PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow | 
| ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast | 
| ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast | 
| ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast | 
| PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast | 
| PSMA2 | 5683 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast | 
| PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast | 
| PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast | 
| ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast | 
| PSMB7 | 5695 | PSMD1 | 5707 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct | 
| Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes | 
|---|---|---|---|---|---|---|---|
| GO:0006521 | regulation of cellular amino acid metabolic process | 1.16e-12 | 1.67e-08 | 7.172 | 6 | 17 | 50 | 
| GO:0000502 | proteasome complex | 2.94e-12 | 4.24e-08 | 6.958 | 6 | 17 | 58 | 
| GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 5.43e-12 | 7.84e-08 | 6.816 | 6 | 19 | 64 | 
| GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.98e-12 | 8.63e-08 | 6.794 | 6 | 22 | 65 | 
| GO:0000082 | G1/S transition of mitotic cell cycle | 8.27e-12 | 1.19e-07 | 5.819 | 7 | 32 | 149 | 
| GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 9.48e-12 | 1.37e-07 | 6.687 | 6 | 22 | 70 | 
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.13e-11 | 1.63e-07 | 6.646 | 6 | 20 | 72 | 
| GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.34e-11 | 1.93e-07 | 6.607 | 6 | 22 | 74 | 
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.45e-11 | 2.10e-07 | 6.587 | 6 | 20 | 75 | 
| GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.00e-11 | 2.89e-07 | 6.512 | 6 | 23 | 79 | 
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 5.12e-11 | 7.38e-07 | 6.293 | 6 | 21 | 92 | 
| GO:0016071 | mRNA metabolic process | 1.43e-10 | 2.06e-06 | 5.238 | 7 | 31 | 223 | 
| GO:0000209 | protein polyubiquitination | 2.11e-10 | 3.04e-06 | 5.958 | 6 | 20 | 116 | 
| GO:0016070 | RNA metabolic process | 2.92e-10 | 4.21e-06 | 5.090 | 7 | 32 | 247 | 
| GO:0042981 | regulation of apoptotic process | 1.00e-09 | 1.45e-05 | 5.587 | 6 | 24 | 150 | 
| GO:0016032 | viral process | 1.46e-09 | 2.10e-05 | 4.170 | 8 | 55 | 534 | 
| GO:0034641 | cellular nitrogen compound metabolic process | 2.22e-09 | 3.20e-05 | 5.398 | 6 | 20 | 171 | 
| GO:0000278 | mitotic cell cycle | 7.19e-09 | 1.04e-04 | 4.427 | 7 | 48 | 391 | 
| GO:0005654 | nucleoplasm | 1.30e-08 | 1.88e-04 | 3.322 | 9 | 76 | 1082 | 
| GO:0005838 | proteasome regulatory particle | 9.64e-08 | 1.39e-03 | 8.231 | 3 | 7 | 12 | 
| GO:0010467 | gene expression | 2.89e-07 | 4.17e-03 | 3.653 | 7 | 59 | 669 | 
| GO:0022624 | proteasome accessory complex | 2.97e-07 | 4.29e-03 | 7.729 | 3 | 8 | 17 | 
| GO:0005839 | proteasome core complex | 3.57e-07 | 5.14e-03 | 7.646 | 3 | 8 | 18 | 
| GO:0004298 | threonine-type endopeptidase activity | 4.23e-07 | 6.10e-03 | 7.568 | 3 | 8 | 19 | 
| GO:0043066 | negative regulation of apoptotic process | 4.96e-07 | 7.15e-03 | 4.088 | 6 | 31 | 424 | 
| GO:0005829 | cytosol | 1.11e-06 | 1.61e-02 | 2.268 | 10 | 132 | 2496 | 
| GO:0006915 | apoptotic process | 2.40e-06 | 3.46e-02 | 3.700 | 6 | 33 | 555 | 
| GO:0070062 | extracellular vesicular exosome | 1.31e-05 | 1.89e-01 | 2.172 | 9 | 104 | 2400 | 
| GO:0019773 | proteasome core complex, alpha-subunit complex | 1.77e-05 | 2.56e-01 | 8.231 | 2 | 4 | 8 | 
| GO:0030234 | enzyme regulator activity | 4.92e-05 | 7.10e-01 | 7.531 | 2 | 3 | 13 | 
| GO:0042176 | regulation of protein catabolic process | 7.57e-05 | 1.00e+00 | 7.231 | 2 | 3 | 16 | 
| GO:0044281 | small molecule metabolic process | 2.05e-04 | 1.00e+00 | 2.574 | 6 | 58 | 1211 | 
| GO:0016020 | membrane | 1.23e-03 | 1.00e+00 | 2.101 | 6 | 90 | 1681 | 
| GO:0004982 | N-formyl peptide receptor activity | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 | 
| GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 | 
| GO:0005055 | laminin receptor activity | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 | 
| GO:0006407 | rRNA export from nucleus | 1.66e-03 | 1.00e+00 | 9.231 | 1 | 1 | 2 | 
| GO:0006928 | cellular component movement | 2.49e-03 | 1.00e+00 | 4.723 | 2 | 7 | 91 | 
| GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 | 
| GO:0030686 | 90S preribosome | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 | 
| GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 | 
| GO:0019788 | NEDD8 ligase activity | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 | 
| GO:0050805 | negative regulation of synaptic transmission | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 4 | 
| GO:0005515 | protein binding | 4.10e-03 | 1.00e+00 | 0.997 | 10 | 184 | 6024 | 
| GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 3 | 5 | 
| GO:0031461 | cullin-RING ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 | 
| GO:0043248 | proteasome assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 | 
| GO:0030891 | VCB complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 2 | 5 | 
| GO:0000730 | DNA recombinase assembly | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 | 
| GO:2000001 | regulation of DNA damage checkpoint | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 5 | 
| GO:0030957 | Tat protein binding | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 3 | 6 | 
| GO:0031466 | Cul5-RING ubiquitin ligase complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 6 | 
| GO:0000028 | ribosomal small subunit assembly | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 7 | 
| GO:0031462 | Cul2-RING ubiquitin ligase complex | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 2 | 7 | 
| GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 | 
| GO:0070688 | MLL5-L complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 8 | 
| GO:0045116 | protein neddylation | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 8 | 
| GO:0001973 | adenosine receptor signaling pathway | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 9 | 
| GO:0005730 | nucleolus | 7.54e-03 | 1.00e+00 | 1.873 | 5 | 69 | 1641 | 
| GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 10 | 
| GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 | 
| GO:0031571 | mitotic G1 DNA damage checkpoint | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 4 | 11 | 
| GO:0050786 | RAGE receptor binding | 9.12e-03 | 1.00e+00 | 6.772 | 1 | 1 | 11 | 
| GO:0031625 | ubiquitin protein ligase binding | 9.22e-03 | 1.00e+00 | 3.755 | 2 | 14 | 178 | 
| GO:0005662 | DNA replication factor A complex | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 13 | 
| GO:0035267 | NuA4 histone acetyltransferase complex | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 4 | 14 | 
| GO:0050998 | nitric-oxide synthase binding | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 1 | 16 | 
| GO:0005634 | nucleus | 1.33e-02 | 1.00e+00 | 1.077 | 8 | 136 | 4559 | 
| GO:0007263 | nitric oxide mediated signal transduction | 1.41e-02 | 1.00e+00 | 6.144 | 1 | 1 | 17 | 
| GO:0035861 | site of double-strand break | 1.49e-02 | 1.00e+00 | 6.061 | 1 | 1 | 18 | 
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 | 
| GO:0048863 | stem cell differentiation | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 | 
| GO:0007214 | gamma-aminobutyric acid signaling pathway | 1.57e-02 | 1.00e+00 | 5.983 | 1 | 1 | 19 | 
| GO:0006298 | mismatch repair | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 20 | 
| GO:0007194 | negative regulation of adenylate cyclase activity | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 21 | 
| GO:0031683 | G-protein beta/gamma-subunit complex binding | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 21 | 
| GO:0032201 | telomere maintenance via semi-conservative replication | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 5 | 21 | 
| GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 4 | 21 | 
| GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 3 | 22 | 
| GO:0051924 | regulation of calcium ion transport | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 | 
| GO:0030863 | cortical cytoskeleton | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 1 | 22 | 
| GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.82e-02 | 1.00e+00 | 5.772 | 1 | 4 | 22 | 
| GO:0043044 | ATP-dependent chromatin remodeling | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 | 
| GO:0005844 | polysome | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 4 | 23 | 
| GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 3 | 23 | 
| GO:0043236 | laminin binding | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 | 
| GO:0006513 | protein monoubiquitination | 1.90e-02 | 1.00e+00 | 5.708 | 1 | 1 | 23 | 
| GO:0006281 | DNA repair | 1.91e-02 | 1.00e+00 | 3.203 | 2 | 18 | 261 | 
| GO:0000722 | telomere maintenance via recombination | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 5 | 25 | 
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 3 | 26 | 
| GO:0043022 | ribosome binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 3 | 27 | 
| GO:0031492 | nucleosomal DNA binding | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 4 | 27 | 
| GO:0007186 | G-protein coupled receptor signaling pathway | 2.31e-02 | 1.00e+00 | 3.056 | 2 | 7 | 289 | 
| GO:0019894 | kinesin binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 28 | 
| GO:0019005 | SCF ubiquitin ligase complex | 2.39e-02 | 1.00e+00 | 5.373 | 1 | 1 | 29 | 
| GO:0006271 | DNA strand elongation involved in DNA replication | 2.47e-02 | 1.00e+00 | 5.324 | 1 | 7 | 30 | 
| GO:0001895 | retina homeostasis | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 1 | 34 | 
| GO:0005834 | heterotrimeric G-protein complex | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 1 | 34 | 
| GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway | 2.79e-02 | 1.00e+00 | 5.144 | 1 | 1 | 34 | 
| GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 35 | 
| GO:0005813 | centrosome | 2.89e-02 | 1.00e+00 | 2.882 | 2 | 14 | 326 | 
| GO:0034332 | adherens junction organization | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 1 | 36 | 
| GO:0051084 | 'de novo' posttranslational protein folding | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 4 | 37 | 
| GO:0006284 | base-excision repair | 3.04e-02 | 1.00e+00 | 5.022 | 1 | 3 | 37 | 
| GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 38 | 
| GO:0070527 | platelet aggregation | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 2 | 38 | 
| GO:0001664 | G-protein coupled receptor binding | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 1 | 38 | 
| GO:0022627 | cytosolic small ribosomal subunit | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 4 | 39 | 
| GO:0000781 | chromosome, telomeric region | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 3 | 39 | 
| GO:0021762 | substantia nigra development | 3.60e-02 | 1.00e+00 | 4.772 | 1 | 2 | 44 | 
| GO:0006283 | transcription-coupled nucleotide-excision repair | 3.76e-02 | 1.00e+00 | 4.708 | 1 | 7 | 46 | 
| GO:0003684 | damaged DNA binding | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 7 | 49 | 
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.32e-02 | 1.00e+00 | 4.503 | 1 | 5 | 53 | 
| GO:0045216 | cell-cell junction organization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 2 | 54 | 
| GO:0000186 | activation of MAPKK activity | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 1 | 54 | 
| GO:0000932 | cytoplasmic mRNA processing body | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 3 | 54 | 
| GO:0000724 | double-strand break repair via homologous recombination | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 3 | 55 | 
| GO:0000723 | telomere maintenance | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 6 | 56 | 
| GO:0019903 | protein phosphatase binding | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 | 
| GO:0006302 | double-strand break repair | 5.04e-02 | 1.00e+00 | 4.277 | 1 | 4 | 62 | 
| GO:0007596 | blood coagulation | 5.32e-02 | 1.00e+00 | 2.401 | 2 | 18 | 455 | 
| GO:0006289 | nucleotide-excision repair | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 11 | 68 | 
| GO:0034329 | cell junction assembly | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 1 | 68 | 
| GO:0003697 | single-stranded DNA binding | 5.52e-02 | 1.00e+00 | 4.144 | 1 | 5 | 68 | 
| GO:0044267 | cellular protein metabolic process | 5.72e-02 | 1.00e+00 | 2.342 | 2 | 29 | 474 | 
| GO:0007584 | response to nutrient | 5.75e-02 | 1.00e+00 | 4.081 | 1 | 4 | 71 | 
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.99e-02 | 1.00e+00 | 4.022 | 1 | 6 | 74 | 
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.07e-02 | 1.00e+00 | 4.002 | 1 | 2 | 75 | 
| GO:0051301 | cell division | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 5 | 81 | 
| GO:0019083 | viral transcription | 6.54e-02 | 1.00e+00 | 3.891 | 1 | 10 | 81 | 
| GO:0047485 | protein N-terminus binding | 6.93e-02 | 1.00e+00 | 3.805 | 1 | 5 | 86 | 
| GO:0006415 | translational termination | 7.01e-02 | 1.00e+00 | 3.788 | 1 | 10 | 87 | 
| GO:0016605 | PML body | 7.08e-02 | 1.00e+00 | 3.772 | 1 | 3 | 88 | 
| GO:0000187 | activation of MAPK activity | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 5 | 90 | 
| GO:0005200 | structural constituent of cytoskeleton | 7.32e-02 | 1.00e+00 | 3.723 | 1 | 8 | 91 | 
| GO:0071456 | cellular response to hypoxia | 7.39e-02 | 1.00e+00 | 3.708 | 1 | 6 | 92 | 
| GO:0006414 | translational elongation | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 13 | 93 | 
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 8.32e-02 | 1.00e+00 | 3.531 | 1 | 10 | 104 | 
| GO:0014069 | postsynaptic density | 8.40e-02 | 1.00e+00 | 3.517 | 1 | 3 | 105 | 
| GO:0006935 | chemotaxis | 8.40e-02 | 1.00e+00 | 3.517 | 1 | 3 | 105 | 
| GO:0030496 | midbody | 8.63e-02 | 1.00e+00 | 3.476 | 1 | 5 | 108 | 
| GO:0015630 | microtubule cytoskeleton | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 4 | 110 | 
| GO:0072562 | blood microparticle | 8.86e-02 | 1.00e+00 | 3.437 | 1 | 3 | 111 | 
| GO:0030529 | ribonucleoprotein complex | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 8 | 112 | 
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 9.09e-02 | 1.00e+00 | 3.398 | 1 | 11 | 114 | 
| GO:0019058 | viral life cycle | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 13 | 115 | 
| GO:0006325 | chromatin organization | 9.39e-02 | 1.00e+00 | 3.348 | 1 | 5 | 118 | 
| GO:0007219 | Notch signaling pathway | 9.54e-02 | 1.00e+00 | 3.324 | 1 | 5 | 120 | 
| GO:0006260 | DNA replication | 9.62e-02 | 1.00e+00 | 3.312 | 1 | 9 | 121 | 
| GO:0006511 | ubiquitin-dependent protein catabolic process | 1.00e-01 | 1.00e+00 | 3.254 | 1 | 5 | 126 | 
| GO:0009615 | response to virus | 1.00e-01 | 1.00e+00 | 3.254 | 1 | 5 | 126 | 
| GO:0000790 | nuclear chromatin | 1.02e-01 | 1.00e+00 | 3.220 | 1 | 9 | 129 | 
| GO:0006413 | translational initiation | 1.04e-01 | 1.00e+00 | 3.198 | 1 | 17 | 131 | 
| GO:0031982 | vesicle | 1.04e-01 | 1.00e+00 | 3.198 | 1 | 9 | 131 | 
| GO:0003735 | structural constituent of ribosome | 1.08e-01 | 1.00e+00 | 3.133 | 1 | 10 | 137 | 
| GO:0006457 | protein folding | 1.13e-01 | 1.00e+00 | 3.071 | 1 | 7 | 143 | 
| GO:0061024 | membrane organization | 1.14e-01 | 1.00e+00 | 3.051 | 1 | 7 | 145 | 
| GO:0045121 | membrane raft | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 8 | 156 | 
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 7 | 165 | 
| GO:0030424 | axon | 1.30e-01 | 1.00e+00 | 2.856 | 1 | 4 | 166 | 
| GO:0005768 | endosome | 1.32e-01 | 1.00e+00 | 2.830 | 1 | 6 | 169 | 
| GO:0007049 | cell cycle | 1.36e-01 | 1.00e+00 | 2.788 | 1 | 2 | 174 | 
| GO:0032403 | protein complex binding | 1.42e-01 | 1.00e+00 | 2.715 | 1 | 10 | 183 | 
| GO:0004872 | receptor activity | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 2 | 189 | 
| GO:0003924 | GTPase activity | 1.52e-01 | 1.00e+00 | 2.609 | 1 | 12 | 197 | 
| GO:0030168 | platelet activation | 1.58e-01 | 1.00e+00 | 2.552 | 1 | 10 | 205 | 
| GO:0004871 | signal transducer activity | 1.60e-01 | 1.00e+00 | 2.531 | 1 | 4 | 208 | 
| GO:0006184 | GTP catabolic process | 1.64e-01 | 1.00e+00 | 2.490 | 1 | 12 | 214 | 
| GO:0007165 | signal transduction | 1.72e-01 | 1.00e+00 | 1.406 | 2 | 24 | 907 | 
| GO:0006412 | translation | 1.75e-01 | 1.00e+00 | 2.386 | 1 | 20 | 230 | 
| GO:0004842 | ubiquitin-protein transferase activity | 1.93e-01 | 1.00e+00 | 2.237 | 1 | 6 | 255 | 
| GO:0019899 | enzyme binding | 2.08e-01 | 1.00e+00 | 2.117 | 1 | 12 | 277 | 
| GO:0005856 | cytoskeleton | 2.17e-01 | 1.00e+00 | 2.046 | 1 | 12 | 291 | 
| GO:0043234 | protein complex | 2.20e-01 | 1.00e+00 | 2.027 | 1 | 18 | 295 | 
| GO:0016567 | protein ubiquitination | 2.20e-01 | 1.00e+00 | 2.027 | 1 | 5 | 295 | 
| GO:0035556 | intracellular signal transduction | 2.25e-01 | 1.00e+00 | 1.988 | 1 | 9 | 303 | 
| GO:0005525 | GTP binding | 2.30e-01 | 1.00e+00 | 1.955 | 1 | 12 | 310 | 
| GO:0019901 | protein kinase binding | 2.34e-01 | 1.00e+00 | 1.923 | 1 | 21 | 317 | 
| GO:0007411 | axon guidance | 2.35e-01 | 1.00e+00 | 1.914 | 1 | 13 | 319 | 
| GO:0008283 | cell proliferation | 2.41e-01 | 1.00e+00 | 1.874 | 1 | 14 | 328 | 
| GO:0007268 | synaptic transmission | 2.44e-01 | 1.00e+00 | 1.856 | 1 | 6 | 332 | 
| GO:0003723 | RNA binding | 2.50e-01 | 1.00e+00 | 1.813 | 1 | 20 | 342 | 
| GO:0005925 | focal adhesion | 2.65e-01 | 1.00e+00 | 1.715 | 1 | 19 | 366 | 
| GO:0007155 | cell adhesion | 2.67e-01 | 1.00e+00 | 1.704 | 1 | 6 | 369 | 
| GO:0008284 | positive regulation of cell proliferation | 2.75e-01 | 1.00e+00 | 1.654 | 1 | 8 | 382 | 
| GO:0005886 | plasma membrane | 3.67e-01 | 1.00e+00 | 0.482 | 3 | 45 | 2582 | 
| GO:0005737 | cytoplasm | 3.86e-01 | 1.00e+00 | 0.352 | 4 | 110 | 3767 | 
| GO:0045087 | innate immune response | 3.97e-01 | 1.00e+00 | 1.012 | 1 | 24 | 596 | 
| GO:0005615 | extracellular space | 5.61e-01 | 1.00e+00 | 0.329 | 1 | 17 | 957 | 
| GO:0008270 | zinc ion binding | 5.77e-01 | 1.00e+00 | 0.270 | 1 | 12 | 997 | 
| GO:0044822 | poly(A) RNA binding | 5.99e-01 | 1.00e+00 | 0.187 | 1 | 49 | 1056 | 
| GO:0005524 | ATP binding | 6.78e-01 | 1.00e+00 | -0.111 | 1 | 60 | 1298 | 
| GO:0046872 | metal ion binding | 6.80e-01 | 1.00e+00 | -0.121 | 1 | 25 | 1307 | 
| GO:0016021 | integral component of membrane | 8.30e-01 | 1.00e+00 | -0.722 | 1 | 27 | 1982 |