Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.924 | 4.26e-15 | 3.12e-03 | 4.73e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
VARS | 7407 | 4 | 0.549 | 1.002 | 80 | Yes | - |
ATP6V1B2 | 526 | 44 | 0.881 | 1.076 | 278 | - | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - |
RSL24D1 | 51187 | 36 | 1.300 | 1.020 | 59 | Yes | - |
EIF6 | 3692 | 14 | 0.700 | 1.013 | 267 | Yes | - |
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
DARS | 1615 | 3 | 0.617 | 1.000 | 110 | Yes | - |
PSMB2 | 5690 | 18 | 0.877 | 1.026 | 117 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
HSPD1 | 3329 | 35 | 0.913 | 1.035 | 286 | Yes | - |
PSMC1 | 5700 | 14 | 0.840 | 1.018 | 137 | Yes | - |
[ EEF1D ] | 1936 | 1 | -0.120 | 0.924 | 117 | - | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
ATP6V1B2 | 526 | DARS | 1615 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | DARS | 1615 | pp | -- | int.I2D: IntAct_Yeast |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
DARS | 1615 | EEF1D | 1936 | pp | -- | int.I2D: BCI |
HSPD1 | 3329 | EIF6 | 3692 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | ATP6V1B2 | 526 | pp | -- | int.I2D: BioGrid_Yeast |
ATP6V1B2 | 526 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast |
ACO2 | 50 | DARS | 1615 | pp | -- | int.I2D: IntAct_Yeast |
ACO2 | 50 | PSMC1 | 5700 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMA1 | 5682 | PSMC1 | 5700 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PGD | 5226 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMB2 | 5690 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
EIF6 | 3692 | RSL24D1 | 51187 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMC1 | 5700 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
EIF6 | 3692 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
EEF1D | 1936 | VARS | 7407 | pp | -- | int.I2D: BioGrid, BCI; int.HPRD: in vitro |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
RPSA | 3921 | VARS | 7407 | pp | -- | int.I2D: IntAct_Yeast |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB7 | 5695 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | EIF6 | 3692 | pp | -- | int.I2D: YeastLow |
EEF1D | 1936 | PSMC1 | 5700 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
HSPD1 | 3329 | RPSA | 3921 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
EEF1D | 1936 | EIF6 | 3692 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
ACO2 | 50 | HSPD1 | 3329 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMC1 | 5700 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core |
ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 1.20e-13 | 1.73e-09 | 6.810 | 7 | 17 | 50 |
GO:0000502 | proteasome complex | 3.60e-13 | 5.19e-09 | 6.596 | 7 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 7.40e-13 | 1.07e-08 | 6.454 | 7 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 8.29e-13 | 1.19e-08 | 6.431 | 7 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.42e-12 | 2.05e-08 | 6.324 | 7 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 1.74e-12 | 2.52e-08 | 6.284 | 7 | 20 | 72 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.13e-12 | 3.07e-08 | 6.244 | 7 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 2.35e-12 | 3.38e-08 | 6.225 | 7 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.42e-12 | 4.93e-08 | 6.150 | 7 | 23 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.02e-11 | 1.48e-07 | 5.930 | 7 | 21 | 92 |
GO:0010467 | gene expression | 4.66e-11 | 6.73e-07 | 3.720 | 11 | 59 | 669 |
GO:0000209 | protein polyubiquitination | 5.36e-11 | 7.73e-07 | 5.596 | 7 | 20 | 116 |
GO:0016071 | mRNA metabolic process | 1.10e-10 | 1.59e-06 | 4.845 | 8 | 31 | 223 |
GO:0016070 | RNA metabolic process | 2.49e-10 | 3.60e-06 | 4.698 | 8 | 32 | 247 |
GO:0000082 | G1/S transition of mitotic cell cycle | 3.15e-10 | 4.55e-06 | 5.234 | 7 | 32 | 149 |
GO:0042981 | regulation of apoptotic process | 3.31e-10 | 4.77e-06 | 5.225 | 7 | 24 | 150 |
GO:0034641 | cellular nitrogen compound metabolic process | 8.30e-10 | 1.20e-05 | 5.036 | 7 | 20 | 171 |
GO:0005829 | cytosol | 1.74e-09 | 2.51e-05 | 2.268 | 15 | 132 | 2496 |
GO:0016032 | viral process | 4.41e-09 | 6.36e-05 | 3.755 | 9 | 55 | 534 |
GO:0005839 | proteasome core complex | 5.14e-09 | 7.41e-05 | 7.476 | 4 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 6.50e-09 | 9.38e-05 | 7.398 | 4 | 8 | 19 |
GO:0043066 | negative regulation of apoptotic process | 1.77e-08 | 2.55e-04 | 3.918 | 8 | 31 | 424 |
GO:0000278 | mitotic cell cycle | 2.51e-07 | 3.62e-03 | 3.842 | 7 | 48 | 391 |
GO:0070062 | extracellular vesicular exosome | 2.72e-07 | 3.92e-03 | 2.118 | 13 | 104 | 2400 |
GO:0005838 | proteasome regulatory particle | 3.57e-07 | 5.14e-03 | 7.646 | 3 | 7 | 12 |
GO:0022624 | proteasome accessory complex | 1.10e-06 | 1.58e-02 | 7.144 | 3 | 8 | 17 |
GO:0006915 | apoptotic process | 2.64e-06 | 3.81e-02 | 3.337 | 7 | 33 | 555 |
GO:0044281 | small molecule metabolic process | 4.87e-06 | 7.03e-02 | 2.574 | 9 | 58 | 1211 |
GO:0005654 | nucleoplasm | 2.17e-05 | 3.12e-01 | 2.567 | 8 | 76 | 1082 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 4.10e-05 | 5.91e-01 | 7.646 | 2 | 4 | 8 |
GO:0005730 | nucleolus | 4.22e-04 | 1.00e+00 | 1.966 | 8 | 69 | 1641 |
GO:0016020 | membrane | 4.98e-04 | 1.00e+00 | 1.931 | 8 | 90 | 1681 |
GO:0043022 | ribosome binding | 5.07e-04 | 1.00e+00 | 5.891 | 2 | 3 | 27 |
GO:0006418 | tRNA aminoacylation for protein translation | 1.23e-03 | 1.00e+00 | 5.254 | 2 | 9 | 42 |
GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0006422 | aspartyl-tRNA aminoacylation | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0048291 | isotype switching to IgG isotypes | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0000054 | ribosomal subunit export from nucleus | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0002368 | B cell cytokine production | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 1 |
GO:0005634 | nucleus | 2.35e-03 | 1.00e+00 | 1.077 | 12 | 136 | 4559 |
GO:0004832 | valine-tRNA ligase activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 2 |
GO:0004815 | aspartate-tRNA ligase activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 2 | 2 |
GO:0003994 | aconitate hydratase activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 2 |
GO:0006412 | translation | 2.74e-03 | 1.00e+00 | 3.386 | 3 | 20 | 230 |
GO:0006458 | 'de novo' protein folding | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 2 | 3 |
GO:0030135 | coated vesicle | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 3 |
GO:0005524 | ATP binding | 3.78e-03 | 1.00e+00 | 1.889 | 6 | 60 | 1298 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0004046 | aminoacylase activity | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 4 |
GO:0005853 | eukaryotic translation elongation factor 1 complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 4 |
GO:0006414 | translational elongation | 5.88e-03 | 1.00e+00 | 4.107 | 2 | 13 | 93 |
GO:0042256 | mature ribosome assembly | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0046696 | lipopolysaccharide receptor complex | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0005638 | lamin filament | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0043023 | ribosomal large subunit binding | 6.23e-03 | 1.00e+00 | 7.324 | 1 | 1 | 5 |
GO:0003688 | DNA replication origin binding | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 6 |
GO:0030957 | Tat protein binding | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 3 | 6 |
GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0006101 | citrate metabolic process | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 6 |
GO:0033180 | proton-transporting V-type ATPase, V1 domain | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0000028 | ribosomal small subunit assembly | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 8.71e-03 | 1.00e+00 | 6.839 | 1 | 2 | 7 |
GO:0070688 | MLL5-L complex | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0051604 | protein maturation | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 8 |
GO:0006450 | regulation of translational fidelity | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 2 | 9 |
GO:0006413 | translational initiation | 1.14e-02 | 1.00e+00 | 3.613 | 2 | 17 | 131 |
GO:0006098 | pentose-phosphate shunt | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 4 | 10 |
GO:0043032 | positive regulation of macrophage activation | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 1 | 10 |
GO:0016887 | ATPase activity | 1.29e-02 | 1.00e+00 | 3.517 | 2 | 7 | 140 |
GO:0032727 | positive regulation of interferon-alpha production | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 11 |
GO:0042273 | ribosomal large subunit biogenesis | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 4 | 13 |
GO:0030234 | enzyme regulator activity | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 13 |
GO:0001530 | lipopolysaccharide binding | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 3 | 13 |
GO:0051131 | chaperone-mediated protein complex assembly | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 4 | 14 |
GO:0046961 | proton-transporting ATPase activity, rotational mechanism | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 3 | 15 |
GO:0042026 | protein refolding | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 2 | 15 |
GO:0046034 | ATP metabolic process | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 3 | 16 |
GO:0044267 | cellular protein metabolic process | 1.99e-02 | 1.00e+00 | 2.342 | 3 | 29 | 474 |
GO:0010243 | response to organonitrogen compound | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 3 | 17 |
GO:0017025 | TBP-class protein binding | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 3 | 17 |
GO:0050870 | positive regulation of T cell activation | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 1 | 17 |
GO:0003746 | translation elongation factor activity | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 3 | 17 |
GO:0015078 | hydrogen ion transmembrane transporter activity | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 3 | 19 |
GO:0032733 | positive regulation of interleukin-10 production | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 1 | 19 |
GO:0042100 | B cell proliferation | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 1 | 21 |
GO:0030863 | cortical cytoskeleton | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 4 | 23 |
GO:0005844 | polysome | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 4 | 23 |
GO:0043236 | laminin binding | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 1 | 23 |
GO:0005515 | protein binding | 2.92e-02 | 1.00e+00 | 0.675 | 12 | 184 | 6024 |
GO:0008135 | translation factor activity, nucleic acid binding | 2.95e-02 | 1.00e+00 | 5.061 | 1 | 7 | 24 |
GO:0042113 | B cell activation | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 1 | 25 |
GO:0015991 | ATP hydrolysis coupled proton transport | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 4 | 26 |
GO:0005759 | mitochondrial matrix | 3.22e-02 | 1.00e+00 | 2.813 | 2 | 14 | 228 |
GO:0050661 | NADP binding | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 27 |
GO:0031492 | nucleosomal DNA binding | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 4 | 27 |
GO:0006099 | tricarboxylic acid cycle | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 28 |
GO:0015992 | proton transport | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 3 | 29 |
GO:0042254 | ribosome biogenesis | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 30 |
GO:0033572 | transferrin transport | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 5 | 30 |
GO:0044822 | poly(A) RNA binding | 3.83e-02 | 1.00e+00 | 1.602 | 4 | 49 | 1056 |
GO:0051701 | interaction with host | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 4 | 32 |
GO:0001895 | retina homeostasis | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 1 | 34 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 4.28e-02 | 1.00e+00 | 4.517 | 1 | 3 | 35 |
GO:0034332 | adherens junction organization | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 1 | 36 |
GO:0090382 | phagosome maturation | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 5 | 36 |
GO:0032755 | positive regulation of interleukin-6 production | 4.40e-02 | 1.00e+00 | 4.476 | 1 | 2 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 4.52e-02 | 1.00e+00 | 4.437 | 1 | 4 | 37 |
GO:0005902 | microvillus | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 2 | 38 |
GO:0070527 | platelet aggregation | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 2 | 38 |
GO:0032729 | positive regulation of interferon-gamma production | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 2 | 39 |
GO:0022627 | cytosolic small ribosomal subunit | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 4 | 39 |
GO:0006200 | ATP catabolic process | 5.05e-02 | 1.00e+00 | 2.456 | 2 | 15 | 292 |
GO:0042110 | T cell activation | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 3 | 42 |
GO:0043234 | protein complex | 5.14e-02 | 1.00e+00 | 2.442 | 2 | 18 | 295 |
GO:0014070 | response to organic cyclic compound | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 4 | 43 |
GO:0021762 | substantia nigra development | 5.35e-02 | 1.00e+00 | 4.187 | 1 | 2 | 44 |
GO:0003743 | translation initiation factor activity | 5.95e-02 | 1.00e+00 | 4.031 | 1 | 8 | 49 |
GO:0006091 | generation of precursor metabolites and energy | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 3 | 50 |
GO:0006986 | response to unfolded protein | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 2 | 50 |
GO:0005905 | coated pit | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 3 | 50 |
GO:0006879 | cellular iron ion homeostasis | 6.18e-02 | 1.00e+00 | 3.974 | 1 | 4 | 51 |
GO:0003725 | double-stranded RNA binding | 6.30e-02 | 1.00e+00 | 3.946 | 1 | 5 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 6.53e-02 | 1.00e+00 | 3.891 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 6.53e-02 | 1.00e+00 | 3.891 | 1 | 3 | 54 |
GO:0002039 | p53 binding | 6.65e-02 | 1.00e+00 | 3.865 | 1 | 7 | 55 |
GO:0012505 | endomembrane system | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 2 | 56 |
GO:0051087 | chaperone binding | 7.12e-02 | 1.00e+00 | 3.764 | 1 | 6 | 59 |
GO:0005737 | cytoplasm | 7.14e-02 | 1.00e+00 | 0.767 | 8 | 110 | 3767 |
GO:0030141 | secretory granule | 7.47e-02 | 1.00e+00 | 3.692 | 1 | 2 | 62 |
GO:0034329 | cell junction assembly | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 8.16e-02 | 1.00e+00 | 3.559 | 1 | 5 | 68 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 8.85e-02 | 1.00e+00 | 3.437 | 1 | 6 | 74 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 9.19e-02 | 1.00e+00 | 3.379 | 1 | 7 | 77 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 9.53e-02 | 1.00e+00 | 3.324 | 1 | 3 | 80 |
GO:0001726 | ruffle | 9.53e-02 | 1.00e+00 | 3.324 | 1 | 4 | 80 |
GO:0019083 | viral transcription | 9.65e-02 | 1.00e+00 | 3.306 | 1 | 10 | 81 |
GO:0006415 | translational termination | 1.03e-01 | 1.00e+00 | 3.203 | 1 | 10 | 87 |
GO:0050821 | protein stabilization | 1.04e-01 | 1.00e+00 | 3.187 | 1 | 2 | 88 |
GO:0042470 | melanosome | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 9 | 91 |
GO:0006928 | cellular component movement | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 8 | 91 |
GO:0051082 | unfolded protein binding | 1.10e-01 | 1.00e+00 | 3.107 | 1 | 5 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.22e-01 | 1.00e+00 | 2.946 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 4 | 105 |
GO:0005739 | mitochondrion | 1.24e-01 | 1.00e+00 | 1.268 | 3 | 28 | 998 |
GO:0015630 | microtubule cytoskeleton | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 4 | 110 |
GO:0006461 | protein complex assembly | 1.30e-01 | 1.00e+00 | 2.852 | 1 | 6 | 111 |
GO:0072562 | blood microparticle | 1.30e-01 | 1.00e+00 | 2.852 | 1 | 3 | 111 |
GO:0030529 | ribonucleoprotein complex | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 8 | 112 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.33e-01 | 1.00e+00 | 2.813 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 1.34e-01 | 1.00e+00 | 2.801 | 1 | 13 | 115 |
GO:0044237 | cellular metabolic process | 1.36e-01 | 1.00e+00 | 2.776 | 1 | 5 | 117 |
GO:0006325 | chromatin organization | 1.38e-01 | 1.00e+00 | 2.764 | 1 | 5 | 118 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 5 | 126 |
GO:0009615 | response to virus | 1.46e-01 | 1.00e+00 | 2.669 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.49e-01 | 1.00e+00 | 2.635 | 1 | 9 | 129 |
GO:0003735 | structural constituent of ribosome | 1.58e-01 | 1.00e+00 | 2.548 | 1 | 10 | 137 |
GO:0008286 | insulin receptor signaling pathway | 1.63e-01 | 1.00e+00 | 2.496 | 1 | 7 | 142 |
GO:0006457 | protein folding | 1.64e-01 | 1.00e+00 | 2.486 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.66e-01 | 1.00e+00 | 2.466 | 1 | 7 | 145 |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 1.66e-01 | 1.00e+00 | 2.466 | 1 | 4 | 145 |
GO:0005769 | early endosome | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 2 | 152 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.87e-01 | 1.00e+00 | 2.280 | 1 | 7 | 165 |
GO:0030424 | axon | 1.88e-01 | 1.00e+00 | 2.271 | 1 | 4 | 166 |
GO:0005765 | lysosomal membrane | 2.25e-01 | 1.00e+00 | 1.981 | 1 | 5 | 203 |
GO:0004871 | signal transducer activity | 2.30e-01 | 1.00e+00 | 1.946 | 1 | 4 | 208 |
GO:0005975 | carbohydrate metabolic process | 2.73e-01 | 1.00e+00 | 1.663 | 1 | 9 | 253 |
GO:0043065 | positive regulation of apoptotic process | 2.87e-01 | 1.00e+00 | 1.580 | 1 | 10 | 268 |
GO:0005743 | mitochondrial inner membrane | 2.95e-01 | 1.00e+00 | 1.532 | 1 | 8 | 277 |
GO:0005856 | cytoskeleton | 3.07e-01 | 1.00e+00 | 1.461 | 1 | 12 | 291 |
GO:0019901 | protein kinase binding | 3.30e-01 | 1.00e+00 | 1.338 | 1 | 21 | 317 |
GO:0043231 | intracellular membrane-bounded organelle | 3.31e-01 | 1.00e+00 | 1.333 | 1 | 9 | 318 |
GO:0007411 | axon guidance | 3.32e-01 | 1.00e+00 | 1.329 | 1 | 13 | 319 |
GO:0005615 | extracellular space | 3.38e-01 | 1.00e+00 | 0.744 | 2 | 17 | 957 |
GO:0005813 | centrosome | 3.38e-01 | 1.00e+00 | 1.297 | 1 | 14 | 326 |
GO:0003723 | RNA binding | 3.51e-01 | 1.00e+00 | 1.228 | 1 | 20 | 342 |
GO:0005925 | focal adhesion | 3.71e-01 | 1.00e+00 | 1.130 | 1 | 19 | 366 |
GO:0007155 | cell adhesion | 3.73e-01 | 1.00e+00 | 1.119 | 1 | 6 | 369 |
GO:0009986 | cell surface | 3.99e-01 | 1.00e+00 | 0.995 | 1 | 11 | 402 |
GO:0055114 | oxidation-reduction process | 4.13e-01 | 1.00e+00 | 0.932 | 1 | 12 | 420 |
GO:0055085 | transmembrane transport | 4.24e-01 | 1.00e+00 | 0.881 | 1 | 10 | 435 |
GO:0007596 | blood coagulation | 4.39e-01 | 1.00e+00 | 0.816 | 1 | 18 | 455 |
GO:0045087 | innate immune response | 5.32e-01 | 1.00e+00 | 0.427 | 1 | 24 | 596 |
GO:0005886 | plasma membrane | 6.50e-01 | 1.00e+00 | -0.103 | 3 | 45 | 2582 |
GO:0007165 | signal transduction | 6.90e-01 | 1.00e+00 | -0.179 | 1 | 24 | 907 |
GO:0006355 | regulation of transcription, DNA-templated | 7.25e-01 | 1.00e+00 | -0.315 | 1 | 18 | 997 |
GO:0003677 | DNA binding | 7.96e-01 | 1.00e+00 | -0.604 | 1 | 28 | 1218 |
GO:0006351 | transcription, DNA-templated | 8.51e-01 | 1.00e+00 | -0.852 | 1 | 31 | 1446 |
GO:0016021 | integral component of membrane | 9.30e-01 | 1.00e+00 | -1.307 | 1 | 27 | 1982 |