Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.931 | 2.28e-15 | 2.68e-03 | 4.25e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
POLR2K | 5440 | 2 | 0.912 | 0.931 | 13 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
[ DPAGT1 ] | 1798 | 1 | 0.325 | 0.931 | 26 | - | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
CDC16 | 8881 | 25 | 0.950 | 1.020 | 80 | Yes | - |
EEF2 | 1938 | 27 | 0.890 | 1.043 | 301 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
CLTC | 1213 | 35 | 0.884 | 1.138 | 247 | Yes | - |
PPP3R1 | 5534 | 3 | -0.462 | 0.994 | 76 | - | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
HSPD1 | 3329 | 35 | 0.913 | 1.035 | 286 | Yes | - |
POLR2B | 5431 | 3 | 0.587 | 0.940 | 146 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
EEF2 | 1938 | HSPD1 | 3329 | pp | -- | int.I2D: YeastLow, YeastMedium |
HSPD1 | 3329 | RPSA | 3921 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
EEF2 | 1938 | POLR2B | 5431 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | EEF2 | 1938 | pp | -- | int.I2D: YeastLow, IntAct_Yeast |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | DPAGT1 | 1798 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | CDC16 | 8881 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
HSPD1 | 3329 | POLR2B | 5431 | pp | -- | int.I2D: YeastLow |
EEF2 | 1938 | PSMD3 | 5709 | pp | -- | int.I2D: Krogan_NonCore |
DPAGT1 | 1798 | PPP3R1 | 5534 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
POLR2B | 5431 | POLR2K | 5440 | pp | -- | int.I2D: BioGrid |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
DPAGT1 | 1798 | POLR2B | 5431 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0016032 | viral process | 1.11e-09 | 1.60e-05 | 3.925 | 9 | 55 | 534 |
GO:0005654 | nucleoplasm | 1.24e-09 | 1.79e-05 | 3.196 | 11 | 76 | 1082 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.68e-09 | 9.64e-05 | 6.116 | 5 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 9.76e-09 | 1.41e-04 | 6.009 | 5 | 22 | 70 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.30e-08 | 1.87e-04 | 5.929 | 5 | 22 | 74 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.81e-08 | 2.61e-04 | 5.834 | 5 | 23 | 79 |
GO:0005829 | cytosol | 4.04e-08 | 5.83e-04 | 2.231 | 13 | 132 | 2496 |
GO:0010467 | gene expression | 1.90e-07 | 2.74e-03 | 3.430 | 8 | 59 | 669 |
GO:0006521 | regulation of cellular amino acid metabolic process | 2.26e-07 | 3.25e-03 | 6.172 | 4 | 17 | 50 |
GO:0000502 | proteasome complex | 4.13e-07 | 5.96e-03 | 5.958 | 4 | 17 | 58 |
GO:0000082 | G1/S transition of mitotic cell cycle | 4.38e-07 | 6.32e-03 | 4.919 | 5 | 32 | 149 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 6.16e-07 | 8.89e-03 | 5.816 | 4 | 19 | 64 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 9.93e-07 | 1.43e-02 | 5.646 | 4 | 20 | 72 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 1.17e-06 | 1.69e-02 | 5.587 | 4 | 20 | 75 |
GO:0000278 | mitotic cell cycle | 2.43e-06 | 3.50e-02 | 3.790 | 6 | 48 | 391 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 2.66e-06 | 3.84e-02 | 5.293 | 4 | 21 | 92 |
GO:0016071 | mRNA metabolic process | 3.21e-06 | 4.63e-02 | 4.337 | 5 | 31 | 223 |
GO:0016070 | RNA metabolic process | 5.30e-06 | 7.64e-02 | 4.190 | 5 | 32 | 247 |
GO:0000209 | protein polyubiquitination | 6.71e-06 | 9.68e-02 | 4.958 | 4 | 20 | 116 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 1.65e-05 | 2.38e-01 | 5.877 | 3 | 7 | 46 |
GO:0042981 | regulation of apoptotic process | 1.86e-05 | 2.68e-01 | 4.587 | 4 | 24 | 150 |
GO:0016020 | membrane | 2.06e-05 | 2.98e-01 | 2.271 | 9 | 90 | 1681 |
GO:0034641 | cellular nitrogen compound metabolic process | 3.11e-05 | 4.48e-01 | 4.398 | 4 | 20 | 171 |
GO:0006289 | nucleotide-excision repair | 5.37e-05 | 7.75e-01 | 5.314 | 3 | 11 | 68 |
GO:0043066 | negative regulation of apoptotic process | 7.16e-05 | 1.00e+00 | 3.410 | 5 | 31 | 424 |
GO:0005838 | proteasome regulatory particle | 7.57e-05 | 1.00e+00 | 7.231 | 2 | 7 | 12 |
GO:0005665 | DNA-directed RNA polymerase II, core complex | 1.37e-04 | 1.00e+00 | 6.816 | 2 | 4 | 16 |
GO:0022624 | proteasome accessory complex | 1.55e-04 | 1.00e+00 | 6.729 | 2 | 8 | 17 |
GO:0006281 | DNA repair | 1.61e-04 | 1.00e+00 | 3.788 | 4 | 18 | 261 |
GO:0005839 | proteasome core complex | 1.75e-04 | 1.00e+00 | 6.646 | 2 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 1.95e-04 | 1.00e+00 | 6.568 | 2 | 8 | 19 |
GO:0006915 | apoptotic process | 2.54e-04 | 1.00e+00 | 3.022 | 5 | 33 | 555 |
GO:0005844 | polysome | 2.88e-04 | 1.00e+00 | 6.293 | 2 | 4 | 23 |
GO:0070062 | extracellular vesicular exosome | 3.59e-04 | 1.00e+00 | 1.757 | 9 | 104 | 2400 |
GO:0006370 | 7-methylguanosine mRNA capping | 4.93e-04 | 1.00e+00 | 5.909 | 2 | 5 | 30 |
GO:0050434 | positive regulation of viral transcription | 1.06e-03 | 1.00e+00 | 5.357 | 2 | 6 | 44 |
GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0008963 | phospho-N-acetylmuramoyl-pentapeptide-transferase activity | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0048291 | isotype switching to IgG isotypes | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0019408 | dolichol biosynthetic process | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0003975 | UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0002368 | B cell cytokine production | 1.11e-03 | 1.00e+00 | 9.816 | 1 | 1 | 1 |
GO:0003725 | double-stranded RNA binding | 1.48e-03 | 1.00e+00 | 5.116 | 2 | 5 | 52 |
GO:0005515 | protein binding | 1.51e-03 | 1.00e+00 | 0.960 | 13 | 184 | 6024 |
GO:0044267 | cellular protein metabolic process | 1.53e-03 | 1.00e+00 | 2.927 | 4 | 29 | 474 |
GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.22e-03 | 1.00e+00 | 8.816 | 1 | 1 | 2 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 2.45e-03 | 1.00e+00 | 4.750 | 2 | 6 | 67 |
GO:0003697 | single-stranded DNA binding | 2.52e-03 | 1.00e+00 | 4.729 | 2 | 5 | 68 |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 2 | 3 |
GO:0006458 | 'de novo' protein folding | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0006047 | UDP-N-acetylglucosamine metabolic process | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0030135 | coated vesicle | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 1 | 3 |
GO:0071439 | clathrin complex | 3.32e-03 | 1.00e+00 | 8.231 | 1 | 2 | 3 |
GO:0043234 | protein complex | 3.89e-03 | 1.00e+00 | 3.196 | 3 | 18 | 295 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0032051 | clathrin light chain binding | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0032549 | ribonucleoside binding | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 2 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0005955 | calcineurin complex | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 2 | 4 |
GO:1903077 | negative regulation of protein localization to plasma membrane | 4.43e-03 | 1.00e+00 | 7.816 | 1 | 1 | 4 |
GO:0044822 | poly(A) RNA binding | 4.60e-03 | 1.00e+00 | 2.094 | 5 | 49 | 1056 |
GO:0006414 | translational elongation | 4.65e-03 | 1.00e+00 | 4.277 | 2 | 13 | 93 |
GO:0019901 | protein kinase binding | 4.76e-03 | 1.00e+00 | 3.093 | 3 | 21 | 317 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 3 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0046696 | lipopolysaccharide receptor complex | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 5.54e-03 | 1.00e+00 | 7.494 | 1 | 1 | 5 |
GO:0003688 | DNA replication origin binding | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 6 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 3 | 6 |
GO:0030118 | clathrin coat | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 6 |
GO:0016757 | transferase activity, transferring glycosyl groups | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 3 | 6 |
GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 1 | 6 |
GO:0006356 | regulation of transcription from RNA polymerase I promoter | 6.64e-03 | 1.00e+00 | 7.231 | 1 | 2 | 6 |
GO:0030529 | ribonucleoprotein complex | 6.68e-03 | 1.00e+00 | 4.009 | 2 | 8 | 112 |
GO:0005819 | spindle | 6.68e-03 | 1.00e+00 | 4.009 | 2 | 7 | 112 |
GO:0000028 | ribosomal small subunit assembly | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 2 | 7 |
GO:0030132 | clathrin coat of coated pit | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 2 | 7 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 2 | 8 |
GO:0001055 | RNA polymerase II activity | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 3 | 8 |
GO:0070688 | MLL5-L complex | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 2 | 8 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 4 | 8 |
GO:0051604 | protein maturation | 8.84e-03 | 1.00e+00 | 6.816 | 1 | 1 | 8 |
GO:0008494 | translation activator activity | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 9 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 1 | 10 |
GO:0043032 | positive regulation of macrophage activation | 1.10e-02 | 1.00e+00 | 6.494 | 1 | 1 | 10 |
GO:0061024 | membrane organization | 1.10e-02 | 1.00e+00 | 3.636 | 2 | 7 | 145 |
GO:0032727 | positive regulation of interferon-alpha production | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 4 | 11 |
GO:0001054 | RNA polymerase I activity | 1.21e-02 | 1.00e+00 | 6.357 | 1 | 3 | 11 |
GO:0005736 | DNA-directed RNA polymerase I complex | 1.32e-02 | 1.00e+00 | 6.231 | 1 | 3 | 12 |
GO:0000398 | mRNA splicing, via spliceosome | 1.39e-02 | 1.00e+00 | 3.459 | 2 | 8 | 164 |
GO:0005662 | DNA replication factor A complex | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 13 |
GO:0001530 | lipopolysaccharide binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 13 |
GO:0051131 | chaperone-mediated protein complex assembly | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 4 | 14 |
GO:0031625 | ubiquitin protein ligase binding | 1.62e-02 | 1.00e+00 | 3.340 | 2 | 14 | 178 |
GO:0042026 | protein refolding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 2 | 15 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.73e-02 | 1.00e+00 | 3.293 | 2 | 8 | 184 |
GO:0042176 | regulation of protein catabolic process | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 3 | 16 |
GO:0050998 | nitric-oxide synthase binding | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 1 | 16 |
GO:0001056 | RNA polymerase III activity | 1.76e-02 | 1.00e+00 | 5.816 | 1 | 3 | 16 |
GO:0005666 | DNA-directed RNA polymerase III complex | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 3 | 17 |
GO:0003746 | translation elongation factor activity | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 3 | 17 |
GO:0050870 | positive regulation of T cell activation | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 1 | 17 |
GO:0006386 | termination of RNA polymerase III transcription | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 3 | 18 |
GO:0035861 | site of double-strand break | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 18 |
GO:0006385 | transcription elongation from RNA polymerase III promoter | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 3 | 18 |
GO:0007088 | regulation of mitosis | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0032733 | positive regulation of interleukin-10 production | 2.09e-02 | 1.00e+00 | 5.568 | 1 | 1 | 19 |
GO:0005680 | anaphase-promoting complex | 2.20e-02 | 1.00e+00 | 5.494 | 1 | 4 | 20 |
GO:0006487 | protein N-linked glycosylation | 2.20e-02 | 1.00e+00 | 5.494 | 1 | 1 | 20 |
GO:0006298 | mismatch repair | 2.20e-02 | 1.00e+00 | 5.494 | 1 | 3 | 20 |
GO:0042100 | B cell proliferation | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 1 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 4 | 21 |
GO:0032201 | telomere maintenance via semi-conservative replication | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 5 | 21 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.41e-02 | 1.00e+00 | 5.357 | 1 | 4 | 22 |
GO:0006362 | transcription elongation from RNA polymerase I promoter | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 3 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 1 | 23 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.52e-02 | 1.00e+00 | 5.293 | 1 | 4 | 23 |
GO:0007067 | mitotic nuclear division | 2.56e-02 | 1.00e+00 | 2.990 | 2 | 14 | 227 |
GO:0008380 | RNA splicing | 2.58e-02 | 1.00e+00 | 2.983 | 2 | 11 | 228 |
GO:0006412 | translation | 2.62e-02 | 1.00e+00 | 2.971 | 2 | 20 | 230 |
GO:0045087 | innate immune response | 2.63e-02 | 1.00e+00 | 2.182 | 3 | 24 | 596 |
GO:0006363 | termination of RNA polymerase I transcription | 2.63e-02 | 1.00e+00 | 5.231 | 1 | 3 | 24 |
GO:0000722 | telomere maintenance via recombination | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 5 | 25 |
GO:0003899 | DNA-directed RNA polymerase activity | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 3 | 25 |
GO:0042113 | B cell activation | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 2.74e-02 | 1.00e+00 | 5.172 | 1 | 1 | 25 |
GO:0005730 | nucleolus | 2.83e-02 | 1.00e+00 | 1.458 | 5 | 69 | 1641 |
GO:1900740 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 4 | 26 |
GO:0070979 | protein K11-linked ubiquitination | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 6 | 26 |
GO:0006361 | transcription initiation from RNA polymerase I promoter | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 3 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.85e-02 | 1.00e+00 | 5.116 | 1 | 3 | 26 |
GO:0043022 | ribosome binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.96e-02 | 1.00e+00 | 5.061 | 1 | 4 | 27 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 3.06e-02 | 1.00e+00 | 5.009 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 3.17e-02 | 1.00e+00 | 4.958 | 1 | 1 | 29 |
GO:0006360 | transcription from RNA polymerase I promoter | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 5 | 30 |
GO:0033572 | transferrin transport | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 5 | 30 |
GO:0006271 | DNA strand elongation involved in DNA replication | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 7 | 30 |
GO:0031623 | receptor internalization | 3.39e-02 | 1.00e+00 | 4.862 | 1 | 2 | 31 |
GO:0007094 | mitotic spindle assembly checkpoint | 3.39e-02 | 1.00e+00 | 4.862 | 1 | 4 | 31 |
GO:0006488 | dolichol-linked oligosaccharide biosynthetic process | 3.49e-02 | 1.00e+00 | 4.816 | 1 | 1 | 32 |
GO:0005634 | nucleus | 3.58e-02 | 1.00e+00 | 0.832 | 9 | 136 | 4559 |
GO:0032588 | trans-Golgi network membrane | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 2 | 34 |
GO:0001895 | retina homeostasis | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 1 | 34 |
GO:0005876 | spindle microtubule | 3.71e-02 | 1.00e+00 | 4.729 | 1 | 2 | 34 |
GO:0034332 | adherens junction organization | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 1 | 36 |
GO:0032755 | positive regulation of interleukin-6 production | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 2 | 36 |
GO:0044281 | small molecule metabolic process | 3.98e-02 | 1.00e+00 | 1.574 | 4 | 58 | 1211 |
GO:0051084 | 'de novo' posttranslational protein folding | 4.03e-02 | 1.00e+00 | 4.607 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 4.03e-02 | 1.00e+00 | 4.607 | 1 | 3 | 37 |
GO:0070527 | platelet aggregation | 4.14e-02 | 1.00e+00 | 4.568 | 1 | 2 | 38 |
GO:0006383 | transcription from RNA polymerase III promoter | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 3 | 39 |
GO:0000781 | chromosome, telomeric region | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 3 | 39 |
GO:0051259 | protein oligomerization | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 1 | 39 |
GO:0032729 | positive regulation of interferon-gamma production | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 2 | 39 |
GO:0022627 | cytosolic small ribosomal subunit | 4.24e-02 | 1.00e+00 | 4.531 | 1 | 4 | 39 |
GO:0042110 | T cell activation | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 3 | 42 |
GO:0030136 | clathrin-coated vesicle | 4.56e-02 | 1.00e+00 | 4.424 | 1 | 4 | 42 |
GO:0006892 | post-Golgi vesicle-mediated transport | 4.67e-02 | 1.00e+00 | 4.390 | 1 | 3 | 43 |
GO:0021762 | substantia nigra development | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 2 | 44 |
GO:0045727 | positive regulation of translation | 4.77e-02 | 1.00e+00 | 4.357 | 1 | 3 | 44 |
GO:0005813 | centrosome | 4.96e-02 | 1.00e+00 | 2.467 | 2 | 14 | 326 |
GO:0003684 | damaged DNA binding | 5.30e-02 | 1.00e+00 | 4.201 | 1 | 7 | 49 |
GO:0006986 | response to unfolded protein | 5.41e-02 | 1.00e+00 | 4.172 | 1 | 2 | 50 |
GO:0005905 | coated pit | 5.41e-02 | 1.00e+00 | 4.172 | 1 | 3 | 50 |
GO:0030176 | integral component of endoplasmic reticulum membrane | 5.72e-02 | 1.00e+00 | 4.088 | 1 | 2 | 53 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 5.72e-02 | 1.00e+00 | 4.088 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 2 | 54 |
GO:0002244 | hematopoietic progenitor cell differentiation | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 1 | 54 |
GO:0097193 | intrinsic apoptotic signaling pathway | 5.93e-02 | 1.00e+00 | 4.035 | 1 | 6 | 55 |
GO:0002039 | p53 binding | 5.93e-02 | 1.00e+00 | 4.035 | 1 | 7 | 55 |
GO:0000724 | double-strand break repair via homologous recombination | 5.93e-02 | 1.00e+00 | 4.035 | 1 | 3 | 55 |
GO:0000723 | telomere maintenance | 6.04e-02 | 1.00e+00 | 4.009 | 1 | 6 | 56 |
GO:0005925 | focal adhesion | 6.10e-02 | 1.00e+00 | 2.300 | 2 | 19 | 366 |
GO:0051087 | chaperone binding | 6.35e-02 | 1.00e+00 | 3.933 | 1 | 6 | 59 |
GO:0032481 | positive regulation of type I interferon production | 6.56e-02 | 1.00e+00 | 3.885 | 1 | 6 | 61 |
GO:0006302 | double-strand break repair | 6.66e-02 | 1.00e+00 | 3.862 | 1 | 4 | 62 |
GO:0019903 | protein phosphatase binding | 6.66e-02 | 1.00e+00 | 3.862 | 1 | 4 | 62 |
GO:0030141 | secretory granule | 6.66e-02 | 1.00e+00 | 3.862 | 1 | 2 | 62 |
GO:0034329 | cell junction assembly | 7.29e-02 | 1.00e+00 | 3.729 | 1 | 1 | 68 |
GO:0042383 | sarcolemma | 7.60e-02 | 1.00e+00 | 3.666 | 1 | 3 | 71 |
GO:0006366 | transcription from RNA polymerase II promoter | 7.73e-02 | 1.00e+00 | 2.105 | 2 | 10 | 419 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 7.90e-02 | 1.00e+00 | 3.607 | 1 | 6 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 8.01e-02 | 1.00e+00 | 3.587 | 1 | 2 | 75 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 8.21e-02 | 1.00e+00 | 3.549 | 1 | 7 | 77 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 8.52e-02 | 1.00e+00 | 3.494 | 1 | 3 | 80 |
GO:0019083 | viral transcription | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 10 | 81 |
GO:0018279 | protein N-linked glycosylation via asparagine | 8.62e-02 | 1.00e+00 | 3.476 | 1 | 2 | 81 |
GO:0006898 | receptor-mediated endocytosis | 8.93e-02 | 1.00e+00 | 3.424 | 1 | 3 | 84 |
GO:0016311 | dephosphorylation | 9.03e-02 | 1.00e+00 | 3.407 | 1 | 3 | 85 |
GO:0047485 | protein N-terminus binding | 9.13e-02 | 1.00e+00 | 3.390 | 1 | 5 | 86 |
GO:0006415 | translational termination | 9.23e-02 | 1.00e+00 | 3.373 | 1 | 10 | 87 |
GO:0050821 | protein stabilization | 9.33e-02 | 1.00e+00 | 3.357 | 1 | 2 | 88 |
GO:0016605 | PML body | 9.33e-02 | 1.00e+00 | 3.357 | 1 | 3 | 88 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 9.53e-02 | 1.00e+00 | 3.324 | 1 | 7 | 90 |
GO:0042470 | melanosome | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 9 | 91 |
GO:0006928 | cellular component movement | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 9.74e-02 | 1.00e+00 | 3.293 | 1 | 6 | 92 |
GO:0071456 | cellular response to hypoxia | 9.74e-02 | 1.00e+00 | 3.293 | 1 | 6 | 92 |
GO:0051082 | unfolded protein binding | 9.84e-02 | 1.00e+00 | 3.277 | 1 | 5 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.09e-01 | 1.00e+00 | 3.116 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 1.10e-01 | 1.00e+00 | 3.102 | 1 | 3 | 105 |
GO:0015630 | microtubule cytoskeleton | 1.15e-01 | 1.00e+00 | 3.035 | 1 | 4 | 110 |
GO:0072562 | blood microparticle | 1.16e-01 | 1.00e+00 | 3.022 | 1 | 3 | 111 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 1.20e-01 | 1.00e+00 | 2.971 | 1 | 13 | 115 |
GO:0006325 | chromatin organization | 1.23e-01 | 1.00e+00 | 2.933 | 1 | 5 | 118 |
GO:0007219 | Notch signaling pathway | 1.25e-01 | 1.00e+00 | 2.909 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 1.26e-01 | 1.00e+00 | 2.897 | 1 | 9 | 121 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.31e-01 | 1.00e+00 | 2.839 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.34e-01 | 1.00e+00 | 2.805 | 1 | 9 | 129 |
GO:0006413 | translational initiation | 1.36e-01 | 1.00e+00 | 2.783 | 1 | 17 | 131 |
GO:0031982 | vesicle | 1.36e-01 | 1.00e+00 | 2.783 | 1 | 9 | 131 |
GO:0003735 | structural constituent of ribosome | 1.42e-01 | 1.00e+00 | 2.718 | 1 | 10 | 137 |
GO:0016887 | ATPase activity | 1.45e-01 | 1.00e+00 | 2.687 | 1 | 7 | 140 |
GO:0006457 | protein folding | 1.47e-01 | 1.00e+00 | 2.656 | 1 | 7 | 143 |
GO:0010628 | positive regulation of gene expression | 1.50e-01 | 1.00e+00 | 2.626 | 1 | 5 | 146 |
GO:0005198 | structural molecule activity | 1.54e-01 | 1.00e+00 | 2.587 | 1 | 5 | 150 |
GO:0005769 | early endosome | 1.56e-01 | 1.00e+00 | 2.568 | 1 | 2 | 152 |
GO:0005516 | calmodulin binding | 1.64e-01 | 1.00e+00 | 2.494 | 1 | 3 | 160 |
GO:0043687 | post-translational protein modification | 1.65e-01 | 1.00e+00 | 2.476 | 1 | 5 | 162 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.68e-01 | 1.00e+00 | 2.450 | 1 | 7 | 165 |
GO:0030424 | axon | 1.69e-01 | 1.00e+00 | 2.441 | 1 | 4 | 166 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.71e-01 | 1.00e+00 | 2.424 | 1 | 12 | 168 |
GO:0006886 | intracellular protein transport | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 5 | 171 |
GO:0019904 | protein domain specific binding | 1.81e-01 | 1.00e+00 | 2.332 | 1 | 6 | 179 |
GO:0032403 | protein complex binding | 1.85e-01 | 1.00e+00 | 2.300 | 1 | 10 | 183 |
GO:0003924 | GTPase activity | 1.98e-01 | 1.00e+00 | 2.194 | 1 | 12 | 197 |
GO:0006184 | GTP catabolic process | 2.13e-01 | 1.00e+00 | 2.075 | 1 | 12 | 214 |
GO:0005759 | mitochondrial matrix | 2.25e-01 | 1.00e+00 | 1.983 | 1 | 14 | 228 |
GO:0004842 | ubiquitin-protein transferase activity | 2.48e-01 | 1.00e+00 | 1.822 | 1 | 6 | 255 |
GO:0043065 | positive regulation of apoptotic process | 2.59e-01 | 1.00e+00 | 1.750 | 1 | 10 | 268 |
GO:0005743 | mitochondrial inner membrane | 2.67e-01 | 1.00e+00 | 1.702 | 1 | 8 | 277 |
GO:0019899 | enzyme binding | 2.67e-01 | 1.00e+00 | 1.702 | 1 | 12 | 277 |
GO:0005856 | cytoskeleton | 2.78e-01 | 1.00e+00 | 1.631 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 2.79e-01 | 1.00e+00 | 1.626 | 1 | 15 | 292 |
GO:0016567 | protein ubiquitination | 2.82e-01 | 1.00e+00 | 1.612 | 1 | 5 | 295 |
GO:0005615 | extracellular space | 2.88e-01 | 1.00e+00 | 0.914 | 2 | 17 | 957 |
GO:0005525 | GTP binding | 2.94e-01 | 1.00e+00 | 1.540 | 1 | 12 | 310 |
GO:0043231 | intracellular membrane-bounded organelle | 3.00e-01 | 1.00e+00 | 1.503 | 1 | 9 | 318 |
GO:0007411 | axon guidance | 3.01e-01 | 1.00e+00 | 1.499 | 1 | 13 | 319 |
GO:0008270 | zinc ion binding | 3.04e-01 | 1.00e+00 | 0.855 | 2 | 12 | 997 |
GO:0003682 | chromatin binding | 3.07e-01 | 1.00e+00 | 1.463 | 1 | 11 | 327 |
GO:0008283 | cell proliferation | 3.08e-01 | 1.00e+00 | 1.459 | 1 | 14 | 328 |
GO:0003723 | RNA binding | 3.19e-01 | 1.00e+00 | 1.398 | 1 | 20 | 342 |
GO:0007155 | cell adhesion | 3.40e-01 | 1.00e+00 | 1.289 | 1 | 6 | 369 |
GO:0009986 | cell surface | 3.64e-01 | 1.00e+00 | 1.165 | 1 | 11 | 402 |
GO:0003677 | DNA binding | 3.97e-01 | 1.00e+00 | 0.566 | 2 | 28 | 1218 |
GO:0007596 | blood coagulation | 4.01e-01 | 1.00e+00 | 0.986 | 1 | 18 | 455 |
GO:0005737 | cytoplasm | 4.10e-01 | 1.00e+00 | 0.259 | 5 | 110 | 3767 |
GO:0005524 | ATP binding | 4.29e-01 | 1.00e+00 | 0.474 | 2 | 60 | 1298 |
GO:0005509 | calcium ion binding | 4.51e-01 | 1.00e+00 | 0.764 | 1 | 5 | 531 |
GO:0005789 | endoplasmic reticulum membrane | 4.76e-01 | 1.00e+00 | 0.661 | 1 | 16 | 570 |
GO:0005886 | plasma membrane | 5.66e-01 | 1.00e+00 | 0.067 | 3 | 45 | 2582 |
GO:0005739 | mitochondrion | 6.83e-01 | 1.00e+00 | -0.147 | 1 | 28 | 998 |
GO:0046872 | metal ion binding | 7.81e-01 | 1.00e+00 | -0.536 | 1 | 25 | 1307 |
GO:0016021 | integral component of membrane | 9.06e-01 | 1.00e+00 | -1.137 | 1 | 27 | 1982 |