int-snw-1798

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.931 2.28e-15 2.68e-03 4.25e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-1798 subnetwork

Genes (16)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
POLR2K 5440 20.9120.93113Yes-
RBX1 9978 971.1851.151139Yes-
PSMB7 5695 480.9821.05257Yes-
[ DPAGT1 ] 1798 10.3250.93126--
PSMA1 5682 610.9961.052123Yes-
RPSA 3921 1561.3271.151152Yes-
RPA2 6118 981.2501.15169Yes-
CDC16 8881 250.9501.02080Yes-
EEF2 1938 270.8901.043301Yes-
PSMD3 5709 570.9861.106146Yes-
CLTC 1213 350.8841.138247Yes-
PPP3R1 5534 3-0.4620.99476--
ACTB 60 1671.1531.151587Yes-
PSMD11 5717 1211.0951.106183Yes-
HSPD1 3329 350.9131.035286Yes-
POLR2B 5431 30.5870.940146Yes-

Interactions (27)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
EEF2 1938 POLR2B 5431 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ACTB 60 DPAGT1 1798 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 POLR2B 5431 pp -- int.I2D: YeastLow
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
DPAGT1 1798 PPP3R1 5534 pp -- int.I2D: IntAct_Yeast
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
POLR2B 5431 POLR2K 5440 pp -- int.I2D: BioGrid
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
DPAGT1 1798 POLR2B 5431 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA

Related GO terms (280)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016032viral process1.11e-091.60e-053.925955534
GO:0005654nucleoplasm1.24e-091.79e-053.19611761082
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.68e-099.64e-056.11652265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle9.76e-091.41e-046.00952270
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.30e-081.87e-045.92952274
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.81e-082.61e-045.83452379
GO:0005829cytosol4.04e-085.83e-042.231131322496
GO:0010467gene expression1.90e-072.74e-033.430859669
GO:0006521regulation of cellular amino acid metabolic process2.26e-073.25e-036.17241750
GO:0000502proteasome complex4.13e-075.96e-035.95841758
GO:0000082G1/S transition of mitotic cell cycle4.38e-076.32e-034.919532149
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest6.16e-078.89e-035.81641964
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent9.93e-071.43e-025.64642072
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.17e-061.69e-025.58742075
GO:0000278mitotic cell cycle2.43e-063.50e-023.790648391
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.66e-063.84e-025.29342192
GO:0016071mRNA metabolic process3.21e-064.63e-024.337531223
GO:0016070RNA metabolic process5.30e-067.64e-024.190532247
GO:0000209protein polyubiquitination6.71e-069.68e-024.958420116
GO:0006283transcription-coupled nucleotide-excision repair1.65e-052.38e-015.8773746
GO:0042981regulation of apoptotic process1.86e-052.68e-014.587424150
GO:0016020membrane2.06e-052.98e-012.2719901681
GO:0034641cellular nitrogen compound metabolic process3.11e-054.48e-014.398420171
GO:0006289nucleotide-excision repair5.37e-057.75e-015.31431168
GO:0043066negative regulation of apoptotic process7.16e-051.00e+003.410531424
GO:0005838proteasome regulatory particle7.57e-051.00e+007.2312712
GO:0005665DNA-directed RNA polymerase II, core complex1.37e-041.00e+006.8162416
GO:0022624proteasome accessory complex1.55e-041.00e+006.7292817
GO:0006281DNA repair1.61e-041.00e+003.788418261
GO:0005839proteasome core complex1.75e-041.00e+006.6462818
GO:0004298threonine-type endopeptidase activity1.95e-041.00e+006.5682819
GO:0006915apoptotic process2.54e-041.00e+003.022533555
GO:0005844polysome2.88e-041.00e+006.2932423
GO:0070062extracellular vesicular exosome3.59e-041.00e+001.75791042400
GO:00063707-methylguanosine mRNA capping4.93e-041.00e+005.9092530
GO:0050434positive regulation of viral transcription1.06e-031.00e+005.3572644
GO:0002842positive regulation of T cell mediated immune response to tumor cell1.11e-031.00e+009.816111
GO:0008963phospho-N-acetylmuramoyl-pentapeptide-transferase activity1.11e-031.00e+009.816111
GO:0048291isotype switching to IgG isotypes1.11e-031.00e+009.816111
GO:0019408dolichol biosynthetic process1.11e-031.00e+009.816111
GO:0003975UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity1.11e-031.00e+009.816111
GO:0002368B cell cytokine production1.11e-031.00e+009.816111
GO:0003725double-stranded RNA binding1.48e-031.00e+005.1162552
GO:0005515protein binding1.51e-031.00e+000.960131846024
GO:0044267cellular protein metabolic process1.53e-031.00e+002.927429474
GO:0004723calcium-dependent protein serine/threonine phosphatase activity2.22e-031.00e+008.816112
GO:0006407rRNA export from nucleus2.22e-031.00e+008.816112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.22e-031.00e+008.816112
GO:0005055laminin receptor activity2.22e-031.00e+008.816112
GO:0006368transcription elongation from RNA polymerase II promoter2.45e-031.00e+004.7502667
GO:0003697single-stranded DNA binding2.52e-031.00e+004.7292568
GO:1900126negative regulation of hyaluronan biosynthetic process3.32e-031.00e+008.231123
GO:0006458'de novo' protein folding3.32e-031.00e+008.231113
GO:0006047UDP-N-acetylglucosamine metabolic process3.32e-031.00e+008.231113
GO:0030135coated vesicle3.32e-031.00e+008.231113
GO:0071439clathrin complex3.32e-031.00e+008.231123
GO:0043234protein complex3.89e-031.00e+003.196318295
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.43e-031.00e+007.816114
GO:003068690S preribosome4.43e-031.00e+007.816114
GO:0032051clathrin light chain binding4.43e-031.00e+007.816114
GO:0019788NEDD8 ligase activity4.43e-031.00e+007.816114
GO:0032549ribonucleoside binding4.43e-031.00e+007.816124
GO:0031467Cul7-RING ubiquitin ligase complex4.43e-031.00e+007.816114
GO:0005955calcineurin complex4.43e-031.00e+007.816124
GO:1903077negative regulation of protein localization to plasma membrane4.43e-031.00e+007.816114
GO:0044822poly(A) RNA binding4.60e-031.00e+002.0945491056
GO:0006414translational elongation4.65e-031.00e+004.27721393
GO:0019901protein kinase binding4.76e-031.00e+003.093321317
GO:0031465Cul4B-RING E3 ubiquitin ligase complex5.54e-031.00e+007.494135
GO:2000001regulation of DNA damage checkpoint5.54e-031.00e+007.494115
GO:0031461cullin-RING ubiquitin ligase complex5.54e-031.00e+007.494115
GO:0043248proteasome assembly5.54e-031.00e+007.494115
GO:0046696lipopolysaccharide receptor complex5.54e-031.00e+007.494115
GO:0030891VCB complex5.54e-031.00e+007.494125
GO:0000730DNA recombinase assembly5.54e-031.00e+007.494115
GO:0003688DNA replication origin binding6.64e-031.00e+007.231126
GO:0030130clathrin coat of trans-Golgi network vesicle6.64e-031.00e+007.231136
GO:0030118clathrin coat6.64e-031.00e+007.231126
GO:0016757transferase activity, transferring glycosyl groups6.64e-031.00e+007.231116
GO:0031466Cul5-RING ubiquitin ligase complex6.64e-031.00e+007.231116
GO:0030957Tat protein binding6.64e-031.00e+007.231136
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex6.64e-031.00e+007.231116
GO:0006356regulation of transcription from RNA polymerase I promoter6.64e-031.00e+007.231126
GO:0030529ribonucleoprotein complex6.68e-031.00e+004.00928112
GO:0005819spindle6.68e-031.00e+004.00927112
GO:0000028ribosomal small subunit assembly7.74e-031.00e+007.009117
GO:0031462Cul2-RING ubiquitin ligase complex7.74e-031.00e+007.009127
GO:0030132clathrin coat of coated pit7.74e-031.00e+007.009127
GO:0031464Cul4A-RING E3 ubiquitin ligase complex8.84e-031.00e+006.816128
GO:0001055RNA polymerase II activity8.84e-031.00e+006.816138
GO:0070688MLL5-L complex8.84e-031.00e+006.816118
GO:0045116protein neddylation8.84e-031.00e+006.816128
GO:0019773proteasome core complex, alpha-subunit complex8.84e-031.00e+006.816148
GO:0051604protein maturation8.84e-031.00e+006.816118
GO:0008494translation activator activity9.94e-031.00e+006.646119
GO:0010569regulation of double-strand break repair via homologous recombination1.10e-021.00e+006.4941110
GO:0043032positive regulation of macrophage activation1.10e-021.00e+006.4941110
GO:0061024membrane organization1.10e-021.00e+003.63627145
GO:0032727positive regulation of interferon-alpha production1.21e-021.00e+006.3571111
GO:0031571mitotic G1 DNA damage checkpoint1.21e-021.00e+006.3571411
GO:0001054RNA polymerase I activity1.21e-021.00e+006.3571311
GO:0005736DNA-directed RNA polymerase I complex1.32e-021.00e+006.2311312
GO:0000398mRNA splicing, via spliceosome1.39e-021.00e+003.45928164
GO:0005662DNA replication factor A complex1.43e-021.00e+006.1161113
GO:0030234enzyme regulator activity1.43e-021.00e+006.1161313
GO:0001530lipopolysaccharide binding1.43e-021.00e+006.1161313
GO:0051131chaperone-mediated protein complex assembly1.43e-021.00e+006.1161113
GO:0035267NuA4 histone acetyltransferase complex1.54e-021.00e+006.0091414
GO:0031625ubiquitin protein ligase binding1.62e-021.00e+003.340214178
GO:0042026protein refolding1.65e-021.00e+005.9091215
GO:0006367transcription initiation from RNA polymerase II promoter1.73e-021.00e+003.29328184
GO:0042176regulation of protein catabolic process1.76e-021.00e+005.8161316
GO:0050998nitric-oxide synthase binding1.76e-021.00e+005.8161116
GO:0001056RNA polymerase III activity1.76e-021.00e+005.8161316
GO:0005666DNA-directed RNA polymerase III complex1.87e-021.00e+005.7291317
GO:0003746translation elongation factor activity1.87e-021.00e+005.7291317
GO:0050870positive regulation of T cell activation1.87e-021.00e+005.7291117
GO:0006386termination of RNA polymerase III transcription1.98e-021.00e+005.6461318
GO:0035861site of double-strand break1.98e-021.00e+005.6461118
GO:0006385transcription elongation from RNA polymerase III promoter1.98e-021.00e+005.6461318
GO:0007088regulation of mitosis1.98e-021.00e+005.6461118
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.09e-021.00e+005.5681119
GO:0048863stem cell differentiation2.09e-021.00e+005.5681119
GO:0032733positive regulation of interleukin-10 production2.09e-021.00e+005.5681119
GO:0005680anaphase-promoting complex2.20e-021.00e+005.4941420
GO:0006487protein N-linked glycosylation2.20e-021.00e+005.4941120
GO:0006298mismatch repair2.20e-021.00e+005.4941320
GO:0042100B cell proliferation2.31e-021.00e+005.4241121
GO:0000718nucleotide-excision repair, DNA damage removal2.31e-021.00e+005.4241421
GO:0032201telomere maintenance via semi-conservative replication2.31e-021.00e+005.4241521
GO:0006297nucleotide-excision repair, DNA gap filling2.41e-021.00e+005.3571322
GO:0030863cortical cytoskeleton2.41e-021.00e+005.3571122
GO:0036464cytoplasmic ribonucleoprotein granule2.41e-021.00e+005.3571422
GO:0006362transcription elongation from RNA polymerase I promoter2.52e-021.00e+005.2931323
GO:0031463Cul3-RING ubiquitin ligase complex2.52e-021.00e+005.2931323
GO:0043236laminin binding2.52e-021.00e+005.2931123
GO:0006513protein monoubiquitination2.52e-021.00e+005.2931123
GO:0043044ATP-dependent chromatin remodeling2.52e-021.00e+005.2931423
GO:0007067mitotic nuclear division2.56e-021.00e+002.990214227
GO:0008380RNA splicing2.58e-021.00e+002.983211228
GO:0006412translation2.62e-021.00e+002.971220230
GO:0045087innate immune response2.63e-021.00e+002.182324596
GO:0006363termination of RNA polymerase I transcription2.63e-021.00e+005.2311324
GO:0000722telomere maintenance via recombination2.74e-021.00e+005.1721525
GO:0003899DNA-directed RNA polymerase activity2.74e-021.00e+005.1721325
GO:0042113B cell activation2.74e-021.00e+005.1721225
GO:0032735positive regulation of interleukin-12 production2.74e-021.00e+005.1721125
GO:0005730nucleolus2.83e-021.00e+001.4585691641
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway2.85e-021.00e+005.1161426
GO:0070979protein K11-linked ubiquitination2.85e-021.00e+005.1161626
GO:0006361transcription initiation from RNA polymerase I promoter2.85e-021.00e+005.1161326
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.85e-021.00e+005.1161326
GO:0043022ribosome binding2.96e-021.00e+005.0611327
GO:0031492nucleosomal DNA binding2.96e-021.00e+005.0611427
GO:0030669clathrin-coated endocytic vesicle membrane3.06e-021.00e+005.0091428
GO:0019894kinesin binding3.06e-021.00e+005.0091128
GO:0019005SCF ubiquitin ligase complex3.17e-021.00e+004.9581129
GO:0006360transcription from RNA polymerase I promoter3.28e-021.00e+004.9091530
GO:0033572transferrin transport3.28e-021.00e+004.9091530
GO:0006271DNA strand elongation involved in DNA replication3.28e-021.00e+004.9091730
GO:0031623receptor internalization3.39e-021.00e+004.8621231
GO:0007094mitotic spindle assembly checkpoint3.39e-021.00e+004.8621431
GO:0006488dolichol-linked oligosaccharide biosynthetic process3.49e-021.00e+004.8161132
GO:0005634nucleus3.58e-021.00e+000.83291364559
GO:0032588trans-Golgi network membrane3.71e-021.00e+004.7291234
GO:0001895retina homeostasis3.71e-021.00e+004.7291134
GO:0005876spindle microtubule3.71e-021.00e+004.7291234
GO:0034332adherens junction organization3.92e-021.00e+004.6461136
GO:0032755positive regulation of interleukin-6 production3.92e-021.00e+004.6461236
GO:0044281small molecule metabolic process3.98e-021.00e+001.5744581211
GO:0051084'de novo' posttranslational protein folding4.03e-021.00e+004.6071437
GO:0006284base-excision repair4.03e-021.00e+004.6071337
GO:0070527platelet aggregation4.14e-021.00e+004.5681238
GO:0006383transcription from RNA polymerase III promoter4.24e-021.00e+004.5311339
GO:0000781chromosome, telomeric region4.24e-021.00e+004.5311339
GO:0051259protein oligomerization4.24e-021.00e+004.5311139
GO:0032729positive regulation of interferon-gamma production4.24e-021.00e+004.5311239
GO:0022627cytosolic small ribosomal subunit4.24e-021.00e+004.5311439
GO:0042110T cell activation4.56e-021.00e+004.4241342
GO:0030136clathrin-coated vesicle4.56e-021.00e+004.4241442
GO:0006892post-Golgi vesicle-mediated transport4.67e-021.00e+004.3901343
GO:0021762substantia nigra development4.77e-021.00e+004.3571244
GO:0045727positive regulation of translation4.77e-021.00e+004.3571344
GO:0005813centrosome4.96e-021.00e+002.467214326
GO:0003684damaged DNA binding5.30e-021.00e+004.2011749
GO:0006986response to unfolded protein5.41e-021.00e+004.1721250
GO:0005905coated pit5.41e-021.00e+004.1721350
GO:0030176integral component of endoplasmic reticulum membrane5.72e-021.00e+004.0881253
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.72e-021.00e+004.0881553
GO:0045216cell-cell junction organization5.83e-021.00e+004.0611254
GO:0002244hematopoietic progenitor cell differentiation5.83e-021.00e+004.0611154
GO:0097193intrinsic apoptotic signaling pathway5.93e-021.00e+004.0351655
GO:0002039p53 binding5.93e-021.00e+004.0351755
GO:0000724double-strand break repair via homologous recombination5.93e-021.00e+004.0351355
GO:0000723telomere maintenance6.04e-021.00e+004.0091656
GO:0005925focal adhesion6.10e-021.00e+002.300219366
GO:0051087chaperone binding6.35e-021.00e+003.9331659
GO:0032481positive regulation of type I interferon production6.56e-021.00e+003.8851661
GO:0006302double-strand break repair6.66e-021.00e+003.8621462
GO:0019903protein phosphatase binding6.66e-021.00e+003.8621462
GO:0030141secretory granule6.66e-021.00e+003.8621262
GO:0034329cell junction assembly7.29e-021.00e+003.7291168
GO:0042383sarcolemma7.60e-021.00e+003.6661371
GO:0006366transcription from RNA polymerase II promoter7.73e-021.00e+002.105210419
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis7.90e-021.00e+003.6071674
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process8.01e-021.00e+003.5871275
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process8.21e-021.00e+003.5491777
GO:0002755MyD88-dependent toll-like receptor signaling pathway8.52e-021.00e+003.4941380
GO:0019083viral transcription8.62e-021.00e+003.47611081
GO:0018279protein N-linked glycosylation via asparagine8.62e-021.00e+003.4761281
GO:0006898receptor-mediated endocytosis8.93e-021.00e+003.4241384
GO:0016311dephosphorylation9.03e-021.00e+003.4071385
GO:0047485protein N-terminus binding9.13e-021.00e+003.3901586
GO:0006415translational termination9.23e-021.00e+003.37311087
GO:0050821protein stabilization9.33e-021.00e+003.3571288
GO:0016605PML body9.33e-021.00e+003.3571388
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II9.53e-021.00e+003.3241790
GO:0042470melanosome9.64e-021.00e+003.3081991
GO:0006928cellular component movement9.64e-021.00e+003.3081791
GO:0005200structural constituent of cytoskeleton9.64e-021.00e+003.3081891
GO:0001649osteoblast differentiation9.74e-021.00e+003.2931692
GO:0071456cellular response to hypoxia9.74e-021.00e+003.2931692
GO:0051082unfolded protein binding9.84e-021.00e+003.2771593
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.09e-011.00e+003.116110104
GO:0014069postsynaptic density1.10e-011.00e+003.10213105
GO:0015630microtubule cytoskeleton1.15e-011.00e+003.03514110
GO:0072562blood microparticle1.16e-011.00e+003.02213111
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.19e-011.00e+002.983111114
GO:0019058viral life cycle1.20e-011.00e+002.971113115
GO:0006325chromatin organization1.23e-011.00e+002.93315118
GO:0007219Notch signaling pathway1.25e-011.00e+002.90915120
GO:0006260DNA replication1.26e-011.00e+002.89719121
GO:0006511ubiquitin-dependent protein catabolic process1.31e-011.00e+002.83915126
GO:0000790nuclear chromatin1.34e-011.00e+002.80519129
GO:0006413translational initiation1.36e-011.00e+002.783117131
GO:0031982vesicle1.36e-011.00e+002.78319131
GO:0003735structural constituent of ribosome1.42e-011.00e+002.718110137
GO:0016887ATPase activity1.45e-011.00e+002.68717140
GO:0006457protein folding1.47e-011.00e+002.65617143
GO:0010628positive regulation of gene expression1.50e-011.00e+002.62615146
GO:0005198structural molecule activity1.54e-011.00e+002.58715150
GO:0005769early endosome1.56e-011.00e+002.56812152
GO:0005516calmodulin binding1.64e-011.00e+002.49413160
GO:0043687post-translational protein modification1.65e-011.00e+002.47615162
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.68e-011.00e+002.45017165
GO:0030424axon1.69e-011.00e+002.44114166
GO:0038095Fc-epsilon receptor signaling pathway1.71e-011.00e+002.424112168
GO:0006886intracellular protein transport1.74e-011.00e+002.39815171
GO:0019904protein domain specific binding1.81e-011.00e+002.33216179
GO:0032403protein complex binding1.85e-011.00e+002.300110183
GO:0003924GTPase activity1.98e-011.00e+002.194112197
GO:0006184GTP catabolic process2.13e-011.00e+002.075112214
GO:0005759mitochondrial matrix2.25e-011.00e+001.983114228
GO:0004842ubiquitin-protein transferase activity2.48e-011.00e+001.82216255
GO:0043065positive regulation of apoptotic process2.59e-011.00e+001.750110268
GO:0005743mitochondrial inner membrane2.67e-011.00e+001.70218277
GO:0019899enzyme binding2.67e-011.00e+001.702112277
GO:0005856cytoskeleton2.78e-011.00e+001.631112291
GO:0006200ATP catabolic process2.79e-011.00e+001.626115292
GO:0016567protein ubiquitination2.82e-011.00e+001.61215295
GO:0005615extracellular space2.88e-011.00e+000.914217957
GO:0005525GTP binding2.94e-011.00e+001.540112310
GO:0043231intracellular membrane-bounded organelle3.00e-011.00e+001.50319318
GO:0007411axon guidance3.01e-011.00e+001.499113319
GO:0008270zinc ion binding3.04e-011.00e+000.855212997
GO:0003682chromatin binding3.07e-011.00e+001.463111327
GO:0008283cell proliferation3.08e-011.00e+001.459114328
GO:0003723RNA binding3.19e-011.00e+001.398120342
GO:0007155cell adhesion3.40e-011.00e+001.28916369
GO:0009986cell surface3.64e-011.00e+001.165111402
GO:0003677DNA binding3.97e-011.00e+000.5662281218
GO:0007596blood coagulation4.01e-011.00e+000.986118455
GO:0005737cytoplasm4.10e-011.00e+000.25951103767
GO:0005524ATP binding4.29e-011.00e+000.4742601298
GO:0005509calcium ion binding4.51e-011.00e+000.76415531
GO:0005789endoplasmic reticulum membrane4.76e-011.00e+000.661116570
GO:0005886plasma membrane5.66e-011.00e+000.0673452582
GO:0005739mitochondrion6.83e-011.00e+00-0.147128998
GO:0046872metal ion binding7.81e-011.00e+00-0.5361251307
GO:0016021integral component of membrane9.06e-011.00e+00-1.1371271982