int-snw-124454

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.936	1.53e-15	2.43e-03	3.96e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-124454 subnetwork

Genes (11)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RSL24D1	51187	36	1.300	1.020	59	Yes	-
ACO2	50	50	1.000	1.076	191	Yes	-
[ EARS2 ]	124454	1	-0.129	0.936	27	-	-
RUVBL1	8607	17	0.720	1.013	343	Yes	-
PSMA2	5683	60	1.093	1.106	89	Yes	-
DDX18	8886	9	0.660	1.013	173	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
POLR1B	84172	4	0.613	0.988	184	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (26)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PGD	5226	POLR1B	84172	pp	--	int.I2D: YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RUVBL1	8607	pp	--	int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMD11	5717	RUVBL1	8607	pp	--	int.I2D: YeastLow
ACO2	50	RUVBL1	8607	pp	--	int.I2D: YeastLow
DDX18	8886	RSL24D1	51187	pp	--	int.I2D: YeastLow, BioGrid_Yeast
RUVBL1	8607	EARS2	124454	pp	--	int.I2D: YeastLow
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
DDX18	8886	EARS2	124454	pp	--	int.I2D: YeastLow
PSMD11	5717	EARS2	124454	pp	--	int.I2D: YeastLow
RUVBL1	8607	POLR1B	84172	pp	--	int.I2D: YeastLow
ACO2	50	POLR1B	84172	pp	--	int.I2D: YeastLow
ACO2	50	DDX18	8886	pp	--	int.I2D: YeastLow
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
ACO2	50	EARS2	124454	pp	--	int.I2D: YeastLow
RUVBL1	8607	DDX18	8886	pp	--	int.I2D: YeastLow
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	POLR1B	84172	pp	--	int.I2D: BIND, BIND_Mouse
DDX18	8886	POLR1B	84172	pp	--	int.I2D: YeastHigh
PGD	5226	DDX18	8886	pp	--	int.I2D: YeastLow
PSMD11	5717	DDX18	8886	pp	--	int.I2D: YeastLow
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
POLR1B	84172	EARS2	124454	pp	--	int.I2D: YeastLow
PSMD11	5717	POLR1B	84172	pp	--	int.I2D: YeastLow
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow

Related GO terms (157)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0035267	NuA4 histone acetyltransferase complex	4.79e-05	6.91e-01	7.549	2	4	14
GO:0010467	gene expression	7.74e-05	1.00e+00	3.293	5	59	669
GO:0016071	mRNA metabolic process	5.49e-04	1.00e+00	4.141	3	31	223
GO:0006521	regulation of cellular amino acid metabolic process	6.35e-04	1.00e+00	5.713	2	17	50
GO:0016070	RNA metabolic process	7.40e-04	1.00e+00	3.993	3	32	247
GO:0005654	nucleoplasm	7.42e-04	1.00e+00	2.599	5	76	1082
GO:0050561	glutamate-tRNA(Gln) ligase activity	7.63e-04	1.00e+00	10.357	1	1	1
GO:0019521	D-gluconate metabolic process	7.63e-04	1.00e+00	10.357	1	1	1
GO:0070127	tRNA aminoacylation for mitochondrial protein translation	7.63e-04	1.00e+00	10.357	1	1	1
GO:0000502	proteasome complex	8.54e-04	1.00e+00	5.499	2	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.04e-03	1.00e+00	5.357	2	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.07e-03	1.00e+00	5.334	2	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.24e-03	1.00e+00	5.227	2	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.31e-03	1.00e+00	5.187	2	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.39e-03	1.00e+00	5.147	2	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.42e-03	1.00e+00	5.128	2	20	75
GO:0051538	3 iron, 4 sulfur cluster binding	1.52e-03	1.00e+00	9.357	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.52e-03	1.00e+00	9.357	1	1	2
GO:0004818	glutamate-tRNA ligase activity	1.52e-03	1.00e+00	9.357	1	1	2
GO:0019322	pentose biosynthetic process	1.52e-03	1.00e+00	9.357	1	2	2
GO:0003994	aconitate hydratase activity	1.52e-03	1.00e+00	9.357	1	1	2
GO:0005055	laminin receptor activity	1.52e-03	1.00e+00	9.357	1	1	2
GO:0006407	rRNA export from nucleus	1.52e-03	1.00e+00	9.357	1	1	2
GO:0006424	glutamyl-tRNA aminoacylation	1.52e-03	1.00e+00	9.357	1	1	2
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.58e-03	1.00e+00	5.053	2	23	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.13e-03	1.00e+00	4.833	2	21	92
GO:0009051	pentose-phosphate shunt, oxidative branch	2.29e-03	1.00e+00	8.772	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	2.29e-03	1.00e+00	8.772	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.05e-03	1.00e+00	8.357	1	1	4
GO:0030686	90S preribosome	3.05e-03	1.00e+00	8.357	1	1	4
GO:0032549	ribonucleoside binding	3.05e-03	1.00e+00	8.357	1	2	4
GO:0030529	ribonucleoprotein complex	3.14e-03	1.00e+00	4.549	2	8	112
GO:0000209	protein polyubiquitination	3.36e-03	1.00e+00	4.499	2	20	116
GO:0006325	chromatin organization	3.48e-03	1.00e+00	4.474	2	5	118
GO:0043248	proteasome assembly	3.81e-03	1.00e+00	8.035	1	1	5
GO:0006102	isocitrate metabolic process	3.81e-03	1.00e+00	8.035	1	1	5
GO:0070062	extracellular vesicular exosome	4.55e-03	1.00e+00	1.713	6	104	2400
GO:0030957	Tat protein binding	4.57e-03	1.00e+00	7.772	1	3	6
GO:0006101	citrate metabolic process	4.57e-03	1.00e+00	7.772	1	1	6
GO:0000028	ribosomal small subunit assembly	5.33e-03	1.00e+00	7.549	1	1	7
GO:0016020	membrane	5.39e-03	1.00e+00	1.963	5	90	1681
GO:0000082	G1/S transition of mitotic cell cycle	5.48e-03	1.00e+00	4.137	2	32	149
GO:0042981	regulation of apoptotic process	5.56e-03	1.00e+00	4.128	2	24	150
GO:0019773	proteasome core complex, alpha-subunit complex	6.09e-03	1.00e+00	7.357	1	4	8
GO:0070688	MLL5-L complex	6.09e-03	1.00e+00	7.357	1	1	8
GO:0000812	Swr1 complex	6.09e-03	1.00e+00	7.357	1	3	8
GO:0016032	viral process	6.67e-03	1.00e+00	2.881	3	55	534
GO:0034641	cellular nitrogen compound metabolic process	7.16e-03	1.00e+00	3.939	2	20	171
GO:0006098	pentose-phosphate shunt	7.60e-03	1.00e+00	7.035	1	4	10
GO:0043968	histone H2A acetylation	9.12e-03	1.00e+00	6.772	1	3	12
GO:0005838	proteasome regulatory particle	9.12e-03	1.00e+00	6.772	1	7	12
GO:0044281	small molecule metabolic process	1.01e-02	1.00e+00	2.115	4	58	1211
GO:0031011	Ino80 complex	1.06e-02	1.00e+00	6.549	1	3	14
GO:0050998	nitric-oxide synthase binding	1.21e-02	1.00e+00	6.357	1	1	16
GO:0005759	mitochondrial matrix	1.25e-02	1.00e+00	3.524	2	14	228
GO:0005524	ATP binding	1.29e-02	1.00e+00	2.015	4	60	1298
GO:0003678	DNA helicase activity	1.29e-02	1.00e+00	6.269	1	3	17
GO:0022624	proteasome accessory complex	1.29e-02	1.00e+00	6.269	1	8	17
GO:0004004	ATP-dependent RNA helicase activity	1.36e-02	1.00e+00	6.187	1	2	18
GO:0005839	proteasome core complex	1.36e-02	1.00e+00	6.187	1	8	18
GO:0048863	stem cell differentiation	1.44e-02	1.00e+00	6.109	1	1	19
GO:0004298	threonine-type endopeptidase activity	1.44e-02	1.00e+00	6.109	1	8	19
GO:0030863	cortical cytoskeleton	1.67e-02	1.00e+00	5.897	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.67e-02	1.00e+00	5.897	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.74e-02	1.00e+00	5.833	1	4	23
GO:0006362	transcription elongation from RNA polymerase I promoter	1.74e-02	1.00e+00	5.833	1	3	23
GO:0043236	laminin binding	1.74e-02	1.00e+00	5.833	1	1	23
GO:0006363	termination of RNA polymerase I transcription	1.82e-02	1.00e+00	5.772	1	3	24
GO:0003899	DNA-directed RNA polymerase activity	1.89e-02	1.00e+00	5.713	1	3	25
GO:0034080	CENP-A containing nucleosome assembly	1.89e-02	1.00e+00	5.713	1	1	25
GO:0006361	transcription initiation from RNA polymerase I promoter	1.97e-02	1.00e+00	5.656	1	3	26
GO:0043022	ribosome binding	2.04e-02	1.00e+00	5.602	1	3	27
GO:0050661	NADP binding	2.04e-02	1.00e+00	5.602	1	2	27
GO:0071339	MLL1 complex	2.04e-02	1.00e+00	5.602	1	3	27
GO:0043967	histone H4 acetylation	2.04e-02	1.00e+00	5.602	1	3	27
GO:0031492	nucleosomal DNA binding	2.04e-02	1.00e+00	5.602	1	4	27
GO:0006099	tricarboxylic acid cycle	2.12e-02	1.00e+00	5.549	1	4	28
GO:0019894	kinesin binding	2.12e-02	1.00e+00	5.549	1	1	28
GO:0006360	transcription from RNA polymerase I promoter	2.27e-02	1.00e+00	5.450	1	5	30
GO:0042254	ribosome biogenesis	2.27e-02	1.00e+00	5.450	1	1	30
GO:0001895	retina homeostasis	2.56e-02	1.00e+00	5.269	1	1	34
GO:0000049	tRNA binding	2.56e-02	1.00e+00	5.269	1	4	34
GO:0051539	4 iron, 4 sulfur cluster binding	2.64e-02	1.00e+00	5.227	1	3	35
GO:0034332	adherens junction organization	2.71e-02	1.00e+00	5.187	1	1	36
GO:0051084	'de novo' posttranslational protein folding	2.79e-02	1.00e+00	5.147	1	4	37
GO:0005829	cytosol	2.85e-02	1.00e+00	1.393	5	132	2496
GO:0005730	nucleolus	2.86e-02	1.00e+00	1.676	4	69	1641
GO:0070527	platelet aggregation	2.86e-02	1.00e+00	5.109	1	2	38
GO:0022627	cytosolic small ribosomal subunit	2.94e-02	1.00e+00	5.071	1	4	39
GO:0032508	DNA duplex unwinding	3.08e-02	1.00e+00	4.999	1	3	41
GO:0006418	tRNA aminoacylation for protein translation	3.16e-02	1.00e+00	4.964	1	9	42
GO:0021762	substantia nigra development	3.31e-02	1.00e+00	4.897	1	2	44
GO:0000278	mitotic cell cycle	3.43e-02	1.00e+00	2.746	2	48	391
GO:0006091	generation of precursor metabolites and energy	3.75e-02	1.00e+00	4.713	1	3	50
GO:0040008	regulation of growth	3.75e-02	1.00e+00	4.713	1	5	50
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.97e-02	1.00e+00	4.629	1	5	53
GO:0043066	negative regulation of apoptotic process	3.98e-02	1.00e+00	2.629	2	31	424
GO:0045216	cell-cell junction organization	4.04e-02	1.00e+00	4.602	1	2	54
GO:0000932	cytoplasmic mRNA processing body	4.04e-02	1.00e+00	4.602	1	3	54
GO:0006310	DNA recombination	4.85e-02	1.00e+00	4.334	1	2	65
GO:0044267	cellular protein metabolic process	4.87e-02	1.00e+00	2.468	2	29	474
GO:0034329	cell junction assembly	5.07e-02	1.00e+00	4.269	1	1	68
GO:0006334	nucleosome assembly	5.36e-02	1.00e+00	4.187	1	2	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	5.50e-02	1.00e+00	4.147	1	6	74
GO:0019083	viral transcription	6.01e-02	1.00e+00	4.017	1	10	81
GO:0006415	translational termination	6.44e-02	1.00e+00	3.914	1	10	87
GO:0006915	apoptotic process	6.46e-02	1.00e+00	2.240	2	33	555
GO:0016363	nuclear matrix	6.73e-02	1.00e+00	3.849	1	12	91
GO:0006928	cellular component movement	6.73e-02	1.00e+00	3.849	1	7	91
GO:0005200	structural constituent of cytoskeleton	6.73e-02	1.00e+00	3.849	1	8	91
GO:0006414	translational elongation	6.87e-02	1.00e+00	3.817	1	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.65e-02	1.00e+00	3.656	1	10	104
GO:0014069	postsynaptic density	7.73e-02	1.00e+00	3.642	1	3	105
GO:0005506	iron ion binding	7.73e-02	1.00e+00	3.642	1	4	105
GO:0005815	microtubule organizing center	8.01e-02	1.00e+00	3.588	1	5	109
GO:0072562	blood microparticle	8.15e-02	1.00e+00	3.562	1	3	111
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	8.36e-02	1.00e+00	3.524	1	11	114
GO:0019058	viral life cycle	8.43e-02	1.00e+00	3.511	1	13	115
GO:0044237	cellular metabolic process	8.57e-02	1.00e+00	3.486	1	5	117
GO:0006511	ubiquitin-dependent protein catabolic process	9.20e-02	1.00e+00	3.379	1	5	126
GO:0009615	response to virus	9.20e-02	1.00e+00	3.379	1	5	126
GO:0000790	nuclear chromatin	9.41e-02	1.00e+00	3.345	1	9	129
GO:0006413	translational initiation	9.55e-02	1.00e+00	3.323	1	17	131
GO:0005634	nucleus	9.78e-02	1.00e+00	0.787	6	136	4559
GO:0003735	structural constituent of ribosome	9.97e-02	1.00e+00	3.259	1	10	137
GO:0016887	ATPase activity	1.02e-01	1.00e+00	3.227	1	7	140
GO:0006457	protein folding	1.04e-01	1.00e+00	3.197	1	7	143
GO:0061024	membrane organization	1.05e-01	1.00e+00	3.177	1	7	145
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.19e-01	1.00e+00	2.990	1	7	165
GO:0030424	axon	1.20e-01	1.00e+00	2.982	1	4	166
GO:0005515	protein binding	1.23e-01	1.00e+00	0.608	7	184	6024
GO:0007067	mitotic nuclear division	1.60e-01	1.00e+00	2.530	1	14	227
GO:0006412	translation	1.62e-01	1.00e+00	2.511	1	20	230
GO:0005739	mitochondrion	1.74e-01	1.00e+00	1.394	2	28	998
GO:0005975	carbohydrate metabolic process	1.77e-01	1.00e+00	2.374	1	9	253
GO:0006281	DNA repair	1.82e-01	1.00e+00	2.329	1	18	261
GO:0007283	spermatogenesis	1.83e-01	1.00e+00	2.323	1	8	262
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.84e-01	1.00e+00	2.312	1	8	264
GO:0044822	poly(A) RNA binding	1.90e-01	1.00e+00	1.312	2	49	1056
GO:0005856	cytoskeleton	2.01e-01	1.00e+00	2.172	1	12	291
GO:0006200	ATP catabolic process	2.02e-01	1.00e+00	2.167	1	15	292
GO:0043234	protein complex	2.03e-01	1.00e+00	2.152	1	18	295
GO:0019901	protein kinase binding	2.17e-01	1.00e+00	2.048	1	21	317
GO:0043231	intracellular membrane-bounded organelle	2.18e-01	1.00e+00	2.044	1	9	318
GO:0007411	axon guidance	2.18e-01	1.00e+00	2.039	1	13	319
GO:0005925	focal adhesion	2.46e-01	1.00e+00	1.841	1	19	366
GO:0007155	cell adhesion	2.48e-01	1.00e+00	1.829	1	6	369
GO:0055114	oxidation-reduction process	2.78e-01	1.00e+00	1.642	1	12	420
GO:0007596	blood coagulation	2.97e-01	1.00e+00	1.527	1	18	455
GO:0005737	cytoplasm	3.18e-01	1.00e+00	0.477	4	110	3767
GO:0045087	innate immune response	3.71e-01	1.00e+00	1.137	1	24	596
GO:0005794	Golgi apparatus	3.78e-01	1.00e+00	1.104	1	15	610
GO:0005615	extracellular space	5.30e-01	1.00e+00	0.454	1	17	957
GO:0003677	DNA binding	6.21e-01	1.00e+00	0.106	1	28	1218
GO:0046872	metal ion binding	6.48e-01	1.00e+00	0.005	1	25	1307
GO:0006351	transcription, DNA-templated	6.87e-01	1.00e+00	-0.141	1	31	1446
GO:0005886	plasma membrane	8.86e-01	1.00e+00	-0.978	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-124454

Statistics

Genes (11)

Interactions (26)

Related GO terms (157)