meta-reg-snw-89910

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
int-snw-56848	tai-screen-luciferase	6.375	2.94e-136	3.59e-07	2.58e-03	24	19
reg-snw-89910	tai-screen-luciferase	4.386	6.32e-21	1.98e-03	2.88e-03	6	4
int-snw-51741	tai-screen-luciferase	6.174	2.67e-126	1.32e-06	4.54e-03	24	19

tai-screen-luciferase-meta-reg-snw-89910 subnetwork

Genes (37)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
RPS8	6202	33	-5.545	7.555	234	-	-
MAPK8	5599	28	-4.403	6.468	153	-	-
CHMP2A	27243	33	-9.037	7.555	41	Yes	Yes
RPS15	6209	30	-5.040	7.011	116	Yes	-
COPA	1314	48	-9.395	5.672	340	Yes	Yes
RNF20	56254	28	-4.564	6.174	18	-	-
PAFAH1B1	5048	18	-2.583	4.586	55	Yes	-
HSF1	3297	46	-4.179	5.027	209	-	Yes
SRC	6714	28	-2.806	6.174	419	Yes	-
COPB2	9276	48	-13.168	9.063	41	Yes	Yes
CKAP5	9793	46	-7.214	5.672	130	Yes	Yes
RPS16	6217	38	-5.444	4.880	205	-	-
CDC42	998	44	-6.960	4.707	276	Yes	Yes
RPS11	6205	44	-6.588	7.555	175	Yes	-
RPS6	6194	44	-5.603	8.046	217	Yes	-
MRPS12	6183	35	-5.421	5.516	341	Yes	-
UBE3B	89910	3	-1.312	4.386	6	-	-
RAN	5901	38	-3.809	4.325	258	Yes	Yes
UBB	7314	30	-4.289	6.428	147	-	-
COPB1	1315	39	-6.221	9.063	118	Yes	Yes
RPS13	6207	43	-6.589	7.555	174	Yes	-
OR1J2	26740	3	-3.429	4.386	12	-	-
RPS24	6229	46	-7.034	8.389	217	Yes	-
RPS9	6203	45	-7.127	7.555	140	Yes	-
TCERG1	10915	28	-3.808	6.174	58	Yes	-
RPS4X	6191	44	-6.747	7.555	263	Yes	-
COPZ1	22818	48	-8.301	9.063	13	Yes	Yes
ATP6V1D	51382	30	-4.131	7.286	149	-	-
RPS15A	6210	36	-5.413	7.555	177	Yes	-
WDR46	9277	31	-4.290	4.226	101	Yes	Yes
WWOX	51741	28	-2.448	6.174	38	-	-
RPS27A	6233	45	-5.631	8.389	344	Yes	-
SKP1	6500	26	-3.750	6.413	203	-	-
NFKBIB	4793	28	-3.978	6.174	78	-	-
SPHK2	56848	17	-3.010	6.375	37	-	-
ARCN1	372	48	-8.232	9.063	118	Yes	Yes
RPS26	6231	43	-7.478	8.046	60	Yes	-

Interactions (91)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC42	998	RPS27A	6233	pp	--	int.I2D: SOURAV_MAPK_HIGH
RPS4X	6191	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast
RPS27A	6233	SKP1	6500	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
RPS11	6205	RPS15	6209	pp	--	int.I2D: INTEROLOG, YeastMedium
RPS11	6205	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
TCERG1	10915	WWOX	51741	pp	--	int.I2D: BioGrid, MINT, Pawson1; int.Mint: MI:0915(physical association)
RPS6	6194	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
SRC	6714	CKAP5	9793	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPS6	6194	RPS26	6231	pp	--	int.I2D: YeastLow
ARCN1	372	RAN	5901	pp	--	int.I2D: YeastLow
CDC42	998	UBB	7314	pp	--	int.I2D: SOURAV_MAPK_HIGH
NFKBIB	4793	UBB	7314	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPS15	6209	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS9	6203	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
PAFAH1B1	5048	UBE3B	89910	pd	>	reg.ITFP.txt: no annot
RPS8	6202	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS9	6203	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast
RPS8	6202	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS9	6203	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
SKP1	6500	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPS13	6207	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	RPS11	6205	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS13	6207	WDR46	9277	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS15	6209	pp	--	int.I2D: BioGrid_Yeast
RPS9	6203	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS9	6203	pp	--	int.I2D: BioGrid_Yeast
UBB	7314	WWOX	51741	pp	--	int.I2D: BCI, HPRD; int.HPRD: in vivo
PAFAH1B1	5048	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
UBB	7314	RNF20	56254	pp	--	int.Intact: MI:0220(ubiquitination reaction); int.I2D: IntAct
MRPS12	6183	RPS15	6209	pp	--	int.I2D: YeastMedium
RPS8	6202	SKP1	6500	pp	--	int.I2D: BioGrid_Yeast
RPS15A	6210	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
RPS8	6202	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast
SRC	6714	WWOX	51741	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
RPS16	6217	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS27A	6233	UBB	7314	pp	--	int.I2D: BIND
RPS4X	6191	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	RPS15	6209	pp	--	int.I2D: YeastLow
RPS4X	6191	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8	6202	RPS9	6203	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS27A	6233	pp	--	int.I2D: YeastLow
RPS6	6194	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPB1	1315	pp	--	int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS8	6202	CHMP2A	27243	pp	--	int.I2D: BioGrid_Yeast
RPS24	6229	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	WDR46	9277	pp	--	int.I2D: YeastLow
HSF1	3297	MAPK8	5599	pp	--	int.I2D: HPRD, INNATEDB; int.HPRD: in vitro, in vivo
HSF1	3297	OR1J2	26740	pd	>	reg.ITFP.txt: no annot
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
NFKBIB	4793	SKP1	6500	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vitro
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
COPB1	1315	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association)
COPA	1314	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS15	6209	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS4X	6191	RPS8	6202	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS15A	6210	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
HSF1	3297	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
RAN	5901	SPHK2	56848	pp	--	int.I2D: IntAct_Yeast, BIND_Yeast, MINT_Yeast, MIPS, YeastLow
RPS4X	6191	RPS15	6209	pp	--	int.I2D: INTEROLOG, YeastMedium
HSF1	3297	UBE3B	89910	pd	>	reg.ITFP.txt: no annot
COPB1	1315	COPB2	9276	pp	--	int.I2D: BioGrid
ARCN1	372	COPB1	1315	pp	--	int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo
RPS9	6203	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPS15	6209	RPS15A	6210	pp	--	int.I2D: YeastMedium, INTEROLOG
RPS6	6194	RPS16	6217	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
RPS6	6194	RPS8	6202	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPS4X	6191	RPS6	6194	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	RPS27A	6233	pp	--	int.I2D: YeastLow
MAPK8	5599	WWOX	51741	pp	--	int.I2D: MINT, HPRD; int.Mint: MI:0915(physical association); int.HPRD: in vivo, yeast 2-hybrid
RPS8	6202	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
RPS16	6217	RPS26	6231	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS15A	6210	RPS27A	6233	pp	--	int.I2D: YeastLow
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
RAN	5901	SKP1	6500	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS15	6209	pp	--	int.I2D: BioGrid_Yeast
RPS24	6229	RPS27A	6233	pp	--	int.I2D: YeastMedium
RPS8	6202	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	PAFAH1B1	5048	pd	<>	reg.ITFP.txt: no annot

Related GO terms (529)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0022627	cytosolic small ribosomal subunit	9.39e-24	1.53e-19	7.085	12	21	39
GO:0019058	viral life cycle	1.68e-23	2.73e-19	5.846	15	25	115
GO:0019083	viral transcription	1.60e-19	2.61e-15	6.030	12	22	81
GO:0006415	translational termination	3.98e-19	6.49e-15	5.927	12	22	87
GO:0006414	translational elongation	9.26e-19	1.51e-14	5.831	12	22	93
GO:0005829	cytosol	2.14e-18	3.49e-14	2.369	30	74	2562
GO:0003735	structural constituent of ribosome	2.54e-18	4.14e-14	5.346	13	24	141
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.78e-18	6.17e-14	5.670	12	22	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.19e-17	1.95e-13	5.537	12	22	114
GO:0016032	viral process	1.68e-17	2.75e-13	3.878	18	37	540
GO:0006413	translational initiation	6.68e-17	1.09e-12	5.337	12	27	131
GO:0016071	mRNA metabolic process	1.09e-15	1.77e-11	4.685	13	29	223
GO:0006412	translation	2.15e-15	3.51e-11	4.609	13	29	235
GO:0015935	small ribosomal subunit	3.22e-15	5.26e-11	7.505	7	9	17
GO:0016070	RNA metabolic process	4.11e-15	6.71e-11	4.537	13	29	247
GO:0016020	membrane	8.69e-12	1.42e-07	2.407	21	48	1746
GO:0061024	membrane organization	2.88e-11	4.69e-07	4.765	9	11	146
GO:0044822	poly(A) RNA binding	3.45e-11	5.63e-07	2.798	17	42	1078
GO:0048205	COPI coating of Golgi vesicle	5.74e-11	9.37e-07	7.406	5	6	13
GO:0030126	COPI vesicle coat	5.74e-11	9.37e-07	7.406	5	6	13
GO:0010467	gene expression	8.42e-11	1.37e-06	3.206	14	36	669
GO:0044267	cellular protein metabolic process	4.93e-10	8.05e-06	3.419	12	29	495
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.32e-09	3.79e-05	6.463	5	6	25
GO:0042274	ribosomal small subunit biogenesis	1.09e-08	1.78e-04	7.200	4	6	12
GO:0005925	focal adhesion	1.41e-06	2.29e-02	3.254	8	23	370
GO:0070062	extracellular vesicular exosome	2.09e-06	3.41e-02	1.658	18	51	2516
GO:0075733	intracellular transport of virus	7.14e-06	1.16e-01	6.282	3	3	17
GO:0006891	intra-Golgi vesicle-mediated transport	7.14e-06	1.16e-01	6.282	3	3	17
GO:0005840	ribosome	9.30e-06	1.52e-01	4.902	4	10	59
GO:0000086	G2/M transition of mitotic cell cycle	1.36e-05	2.22e-01	4.009	5	6	137
GO:0034146	toll-like receptor 5 signaling pathway	1.37e-05	2.24e-01	4.763	4	5	65
GO:0034166	toll-like receptor 10 signaling pathway	1.37e-05	2.24e-01	4.763	4	5	65
GO:0000056	ribosomal small subunit export from nucleus	1.50e-05	2.45e-01	8.200	2	2	3
GO:0036464	cytoplasmic ribonucleoprotein granule	1.60e-05	2.62e-01	5.911	3	5	22
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	1.95e-05	3.18e-01	4.635	4	5	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	1.95e-05	3.18e-01	4.635	4	5	71
GO:0034162	toll-like receptor 9 signaling pathway	2.06e-05	3.36e-01	4.615	4	5	72
GO:0034134	toll-like receptor 2 signaling pathway	2.18e-05	3.55e-01	4.595	4	5	73
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	2.55e-05	4.16e-01	4.537	4	5	76
GO:0002756	MyD88-independent toll-like receptor signaling pathway	2.83e-05	4.62e-01	4.500	4	5	78
GO:0019843	rRNA binding	3.02e-05	4.93e-01	5.615	3	4	27
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	3.13e-05	5.10e-01	4.463	4	5	80
GO:0034138	toll-like receptor 3 signaling pathway	3.13e-05	5.10e-01	4.463	4	5	80
GO:0006886	intracellular protein transport	4.18e-05	6.83e-01	3.672	5	6	173
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.98e-05	8.13e-01	7.463	2	3	5
GO:0033119	negative regulation of RNA splicing	4.98e-05	8.13e-01	7.463	2	2	5
GO:0034142	toll-like receptor 4 signaling pathway	6.40e-05	1.00e+00	4.200	4	5	96
GO:0006364	rRNA processing	6.40e-05	1.00e+00	4.200	4	8	96
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	7.27e-05	1.00e+00	5.200	3	3	36
GO:0007097	nuclear migration	1.04e-04	1.00e+00	6.978	2	2	7
GO:0002224	toll-like receptor signaling pathway	1.05e-04	1.00e+00	4.017	4	5	109
GO:0030529	ribonucleoprotein complex	1.25e-04	1.00e+00	3.952	4	8	114
GO:0005515	protein binding	2.02e-04	1.00e+00	0.848	25	87	6127
GO:0007254	JNK cascade	2.07e-04	1.00e+00	4.698	3	3	51
GO:0051403	stress-activated MAPK cascade	2.46e-04	1.00e+00	4.615	3	4	54
GO:0016197	endosomal transport	3.04e-04	1.00e+00	4.512	3	3	58
GO:0019082	viral protein processing	3.25e-04	1.00e+00	6.200	2	2	12
GO:0032481	positive regulation of type I interferon production	3.53e-04	1.00e+00	4.439	3	3	61
GO:0000082	G1/S transition of mitotic cell cycle	3.58e-04	1.00e+00	3.556	4	11	150
GO:0043065	positive regulation of apoptotic process	3.61e-04	1.00e+00	3.009	5	6	274
GO:0032479	regulation of type I interferon production	3.84e-04	1.00e+00	6.085	2	2	13
GO:0043066	negative regulation of apoptotic process	3.90e-04	1.00e+00	2.612	6	14	433
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.29e-04	1.00e+00	4.241	3	8	70
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.22e-04	1.00e+00	4.160	3	8	74
GO:0019068	virion assembly	6.66e-04	1.00e+00	5.698	2	2	17
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	7.53e-04	1.00e+00	4.066	3	8	79
GO:0007173	epidermal growth factor receptor signaling pathway	8.87e-04	1.00e+00	3.208	4	5	191
GO:0007220	Notch receptor processing	1.12e-03	1.00e+00	5.326	2	2	22
GO:0001649	osteoblast differentiation	1.29e-03	1.00e+00	3.800	3	3	95
GO:0071456	cellular response to hypoxia	1.41e-03	1.00e+00	3.755	3	3	98
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	1.45e-03	1.00e+00	5.141	2	2	25
GO:0005844	polysome	1.45e-03	1.00e+00	5.141	2	2	25
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.57e-03	1.00e+00	5.085	2	2	26
GO:0005978	glycogen biosynthetic process	1.57e-03	1.00e+00	5.085	2	2	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.57e-03	1.00e+00	5.085	2	2	26
GO:0007067	mitotic nuclear division	1.79e-03	1.00e+00	2.933	4	7	231
GO:0000278	mitotic cell cycle	1.93e-03	1.00e+00	2.470	5	16	398
GO:0003713	transcription coactivator activity	2.03e-03	1.00e+00	2.884	4	6	239
GO:2001286	regulation of caveolin-mediated endocytosis	2.27e-03	1.00e+00	8.785	1	1	1
GO:0000235	astral microtubule	2.27e-03	1.00e+00	8.785	1	1	1
GO:0071393	cellular response to progesterone stimulus	2.27e-03	1.00e+00	8.785	1	1	1
GO:0033176	proton-transporting V-type ATPase complex	2.27e-03	1.00e+00	8.785	1	1	1
GO:0006669	sphinganine-1-phosphate biosynthetic process	2.27e-03	1.00e+00	8.785	1	1	1
GO:0022605	oogenesis stage	2.27e-03	1.00e+00	8.785	1	1	1
GO:0021691	cerebellar Purkinje cell layer maturation	2.27e-03	1.00e+00	8.785	1	1	1
GO:0051660	establishment of centrosome localization	2.27e-03	1.00e+00	8.785	1	1	1
GO:0046469	platelet activating factor metabolic process	2.27e-03	1.00e+00	8.785	1	1	1
GO:0097190	apoptotic signaling pathway	2.28e-03	1.00e+00	3.512	3	3	116
GO:0000209	protein polyubiquitination	2.28e-03	1.00e+00	3.512	3	7	116
GO:0032480	negative regulation of type I interferon production	2.38e-03	1.00e+00	4.785	2	2	32
GO:0051219	phosphoprotein binding	2.38e-03	1.00e+00	4.785	2	4	32
GO:0045087	innate immune response	2.42e-03	1.00e+00	2.103	6	11	616
GO:0051092	positive regulation of NF-kappaB transcription factor activity	2.82e-03	1.00e+00	3.404	3	3	125
GO:0007219	Notch signaling pathway	2.82e-03	1.00e+00	3.404	3	4	125
GO:0034332	adherens junction organization	3.00e-03	1.00e+00	4.615	2	4	36
GO:0007179	transforming growth factor beta receptor signaling pathway	3.15e-03	1.00e+00	3.348	3	4	130
GO:0048011	neurotrophin TRK receptor signaling pathway	3.28e-03	1.00e+00	2.692	4	5	273
GO:0007249	I-kappaB kinase/NF-kappaB signaling	3.88e-03	1.00e+00	4.427	2	4	41
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	4.26e-03	1.00e+00	4.359	2	2	43
GO:0008481	sphinganine kinase activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0060661	submandibular salivary gland formation	4.53e-03	1.00e+00	7.785	1	1	2
GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	4.53e-03	1.00e+00	7.785	1	1	2
GO:0036035	osteoclast development	4.53e-03	1.00e+00	7.785	1	1	2
GO:0017050	D-erythro-sphingosine kinase activity	4.53e-03	1.00e+00	7.785	1	1	2
GO:0071338	positive regulation of hair follicle cell proliferation	4.53e-03	1.00e+00	7.785	1	1	2
GO:0051081	nuclear envelope disassembly	4.53e-03	1.00e+00	7.785	1	1	2
GO:0010632	regulation of epithelial cell migration	4.53e-03	1.00e+00	7.785	1	1	2
GO:0090135	actin filament branching	4.53e-03	1.00e+00	7.785	1	1	2
GO:0008344	adult locomotory behavior	5.07e-03	1.00e+00	4.230	2	2	47
GO:0005198	structural molecule activity	5.53e-03	1.00e+00	3.057	3	5	159
GO:0008543	fibroblast growth factor receptor signaling pathway	5.53e-03	1.00e+00	3.057	3	3	159
GO:0043005	neuron projection	5.73e-03	1.00e+00	3.039	3	6	161
GO:0030666	endocytic vesicle membrane	6.64e-03	1.00e+00	4.030	2	2	54
GO:0038095	Fc-epsilon receptor signaling pathway	6.76e-03	1.00e+00	2.952	3	3	171
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	6.79e-03	1.00e+00	7.200	1	1	3
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	6.79e-03	1.00e+00	7.200	1	1	3
GO:0003161	cardiac conduction system development	6.79e-03	1.00e+00	7.200	1	1	3
GO:0090045	positive regulation of deacetylase activity	6.79e-03	1.00e+00	7.200	1	1	3
GO:0035033	histone deacetylase regulator activity	6.79e-03	1.00e+00	7.200	1	1	3
GO:2000017	positive regulation of determination of dorsal identity	6.79e-03	1.00e+00	7.200	1	1	3
GO:0045505	dynein intermediate chain binding	6.79e-03	1.00e+00	7.200	1	1	3
GO:0051683	establishment of Golgi localization	6.79e-03	1.00e+00	7.200	1	2	3
GO:0006670	sphingosine metabolic process	6.79e-03	1.00e+00	7.200	1	1	3
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	6.79e-03	1.00e+00	7.200	1	1	3
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	6.79e-03	1.00e+00	7.200	1	1	3
GO:0004705	JUN kinase activity	6.79e-03	1.00e+00	7.200	1	1	3
GO:0021540	corpus callosum morphogenesis	6.79e-03	1.00e+00	7.200	1	1	3
GO:0034191	apolipoprotein A-I receptor binding	9.04e-03	1.00e+00	6.785	1	1	4
GO:0032463	negative regulation of protein homooligomerization	9.04e-03	1.00e+00	6.785	1	1	4
GO:0051902	negative regulation of mitochondrial depolarization	9.04e-03	1.00e+00	6.785	1	1	4
GO:0031062	positive regulation of histone methylation	9.04e-03	1.00e+00	6.785	1	1	4
GO:0060684	epithelial-mesenchymal cell signaling	9.04e-03	1.00e+00	6.785	1	1	4
GO:0070851	growth factor receptor binding	9.04e-03	1.00e+00	6.785	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	9.04e-03	1.00e+00	6.785	1	1	4
GO:0090231	regulation of spindle checkpoint	9.04e-03	1.00e+00	6.785	1	1	4
GO:0072384	organelle transport along microtubule	9.04e-03	1.00e+00	6.785	1	2	4
GO:0007258	JUN phosphorylation	9.04e-03	1.00e+00	6.785	1	1	4
GO:0048664	neuron fate determination	9.04e-03	1.00e+00	6.785	1	1	4
GO:0033503	HULC complex	9.04e-03	1.00e+00	6.785	1	1	4
GO:0031063	regulation of histone deacetylation	9.04e-03	1.00e+00	6.785	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	9.04e-03	1.00e+00	6.785	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	9.04e-03	1.00e+00	6.785	1	1	4
GO:0033625	positive regulation of integrin activation	9.04e-03	1.00e+00	6.785	1	1	4
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	9.23e-03	1.00e+00	3.785	2	2	64
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	9.51e-03	1.00e+00	3.763	2	6	65
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.51e-03	1.00e+00	3.763	2	6	65
GO:0031295	T cell costimulation	1.01e-02	1.00e+00	3.719	2	3	67
GO:0018105	peptidyl-serine phosphorylation	1.07e-02	1.00e+00	3.676	2	5	69
GO:2000641	regulation of early endosome to late endosome transport	1.13e-02	1.00e+00	6.463	1	1	5
GO:0036336	dendritic cell migration	1.13e-02	1.00e+00	6.463	1	1	5
GO:0035088	establishment or maintenance of apical/basal cell polarity	1.13e-02	1.00e+00	6.463	1	1	5
GO:0051385	response to mineralocorticoid	1.13e-02	1.00e+00	6.463	1	1	5
GO:1902188	positive regulation of viral release from host cell	1.13e-02	1.00e+00	6.463	1	1	5
GO:0097300	programmed necrotic cell death	1.13e-02	1.00e+00	6.463	1	1	5
GO:0031256	leading edge membrane	1.13e-02	1.00e+00	6.463	1	1	5
GO:0031023	microtubule organizing center organization	1.13e-02	1.00e+00	6.463	1	1	5
GO:0071803	positive regulation of podosome assembly	1.13e-02	1.00e+00	6.463	1	1	5
GO:0046834	lipid phosphorylation	1.13e-02	1.00e+00	6.463	1	1	5
GO:0008284	positive regulation of cell proliferation	1.16e-02	1.00e+00	2.170	4	7	392
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.19e-02	1.00e+00	3.595	2	6	73
GO:0003729	mRNA binding	1.19e-02	1.00e+00	3.595	2	3	73
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.32e-02	1.00e+00	3.518	2	6	77
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	1.32e-02	1.00e+00	3.518	2	4	77
GO:0050847	progesterone receptor signaling pathway	1.35e-02	1.00e+00	6.200	1	1	6
GO:0007143	female meiotic division	1.35e-02	1.00e+00	6.200	1	1	6
GO:0002309	T cell proliferation involved in immune response	1.35e-02	1.00e+00	6.200	1	1	6
GO:0045182	translation regulator activity	1.35e-02	1.00e+00	6.200	1	2	6
GO:0045056	transcytosis	1.35e-02	1.00e+00	6.200	1	1	6
GO:0060789	hair follicle placode formation	1.35e-02	1.00e+00	6.200	1	1	6
GO:0008090	retrograde axon cargo transport	1.35e-02	1.00e+00	6.200	1	1	6
GO:0048554	positive regulation of metalloenzyme activity	1.35e-02	1.00e+00	6.200	1	1	6
GO:0050792	regulation of viral process	1.35e-02	1.00e+00	6.200	1	1	6
GO:0001667	ameboidal-type cell migration	1.35e-02	1.00e+00	6.200	1	1	6
GO:0034452	dynactin binding	1.35e-02	1.00e+00	6.200	1	1	6
GO:0006924	activation-induced cell death of T cells	1.35e-02	1.00e+00	6.200	1	2	6
GO:0071222	cellular response to lipopolysaccharide	1.45e-02	1.00e+00	3.445	2	4	81
GO:0010447	response to acidic pH	1.58e-02	1.00e+00	5.978	1	1	7
GO:0060136	embryonic process involved in female pregnancy	1.58e-02	1.00e+00	5.978	1	1	7
GO:0043497	regulation of protein heterodimerization activity	1.58e-02	1.00e+00	5.978	1	1	7
GO:0050658	RNA transport	1.58e-02	1.00e+00	5.978	1	1	7
GO:0061512	protein localization to cilium	1.58e-02	1.00e+00	5.978	1	1	7
GO:0003334	keratinocyte development	1.58e-02	1.00e+00	5.978	1	1	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.58e-02	1.00e+00	5.978	1	1	7
GO:0001961	positive regulation of cytokine-mediated signaling pathway	1.58e-02	1.00e+00	5.978	1	1	7
GO:0000028	ribosomal small subunit assembly	1.58e-02	1.00e+00	5.978	1	3	7
GO:0034101	erythrocyte homeostasis	1.58e-02	1.00e+00	5.978	1	1	7
GO:0010907	positive regulation of glucose metabolic process	1.58e-02	1.00e+00	5.978	1	1	7
GO:0030157	pancreatic juice secretion	1.58e-02	1.00e+00	5.978	1	1	7
GO:0017145	stem cell division	1.58e-02	1.00e+00	5.978	1	1	7
GO:0000930	gamma-tubulin complex	1.58e-02	1.00e+00	5.978	1	1	7
GO:0050852	T cell receptor signaling pathway	1.69e-02	1.00e+00	3.326	2	2	88
GO:0000187	activation of MAPK activity	1.77e-02	1.00e+00	3.293	2	3	90
GO:0031512	motile primary cilium	1.80e-02	1.00e+00	5.785	1	1	8
GO:0039702	viral budding via host ESCRT complex	1.80e-02	1.00e+00	5.785	1	1	8
GO:0043114	regulation of vascular permeability	1.80e-02	1.00e+00	5.785	1	1	8
GO:0045124	regulation of bone resorption	1.80e-02	1.00e+00	5.785	1	1	8
GO:0051489	regulation of filopodium assembly	1.80e-02	1.00e+00	5.785	1	1	8
GO:0033523	histone H2B ubiquitination	1.80e-02	1.00e+00	5.785	1	1	8
GO:0007172	signal complex assembly	1.80e-02	1.00e+00	5.785	1	1	8
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.92e-02	1.00e+00	3.230	2	7	94
GO:0043025	neuronal cell body	1.96e-02	1.00e+00	2.381	3	5	254
GO:0004842	ubiquitin-protein transferase activity	2.00e-02	1.00e+00	2.370	3	3	256
GO:0071732	cellular response to nitric oxide	2.02e-02	1.00e+00	5.615	1	1	9
GO:0021895	cerebral cortex neuron differentiation	2.02e-02	1.00e+00	5.615	1	1	9
GO:0090136	epithelial cell-cell adhesion	2.02e-02	1.00e+00	5.615	1	2	9
GO:0047497	mitochondrion transport along microtubule	2.02e-02	1.00e+00	5.615	1	1	9
GO:0032319	regulation of Rho GTPase activity	2.02e-02	1.00e+00	5.615	1	1	9
GO:0046628	positive regulation of insulin receptor signaling pathway	2.02e-02	1.00e+00	5.615	1	1	9
GO:0005737	cytoplasm	2.16e-02	1.00e+00	0.735	15	65	3976
GO:0005798	Golgi-associated vesicle	2.24e-02	1.00e+00	5.463	1	1	10
GO:0031274	positive regulation of pseudopodium assembly	2.24e-02	1.00e+00	5.463	1	2	10
GO:0022407	regulation of cell-cell adhesion	2.24e-02	1.00e+00	5.463	1	1	10
GO:0001675	acrosome assembly	2.24e-02	1.00e+00	5.463	1	1	10
GO:0060047	heart contraction	2.24e-02	1.00e+00	5.463	1	1	10
GO:0045502	dynein binding	2.47e-02	1.00e+00	5.326	1	1	11
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	2.47e-02	1.00e+00	5.326	1	1	11
GO:0051895	negative regulation of focal adhesion assembly	2.47e-02	1.00e+00	5.326	1	1	11
GO:0045120	pronucleus	2.47e-02	1.00e+00	5.326	1	1	11
GO:2000573	positive regulation of DNA biosynthetic process	2.47e-02	1.00e+00	5.326	1	2	11
GO:0060065	uterus development	2.47e-02	1.00e+00	5.326	1	1	11
GO:0010390	histone monoubiquitination	2.47e-02	1.00e+00	5.326	1	1	11
GO:0035518	histone H2A monoubiquitination	2.47e-02	1.00e+00	5.326	1	2	11
GO:0021819	layer formation in cerebral cortex	2.47e-02	1.00e+00	5.326	1	1	11
GO:0061136	regulation of proteasomal protein catabolic process	2.69e-02	1.00e+00	5.200	1	1	12
GO:0007051	spindle organization	2.69e-02	1.00e+00	5.200	1	1	12
GO:0043149	stress fiber assembly	2.69e-02	1.00e+00	5.200	1	2	12
GO:0047496	vesicle transport along microtubule	2.69e-02	1.00e+00	5.200	1	1	12
GO:1903543	positive regulation of exosomal secretion	2.69e-02	1.00e+00	5.200	1	1	12
GO:1901214	regulation of neuron death	2.69e-02	1.00e+00	5.200	1	1	12
GO:0031929	TOR signaling	2.91e-02	1.00e+00	5.085	1	1	13
GO:0071398	cellular response to fatty acid	2.91e-02	1.00e+00	5.085	1	2	13
GO:0060444	branching involved in mammary gland duct morphogenesis	2.91e-02	1.00e+00	5.085	1	1	13
GO:0004143	diacylglycerol kinase activity	2.91e-02	1.00e+00	5.085	1	1	13
GO:0006006	glucose metabolic process	2.97e-02	1.00e+00	2.890	2	4	119
GO:0035371	microtubule plus-end	3.13e-02	1.00e+00	4.978	1	1	14
GO:0031333	negative regulation of protein complex assembly	3.13e-02	1.00e+00	4.978	1	1	14
GO:0050662	coenzyme binding	3.13e-02	1.00e+00	4.978	1	1	14
GO:0017016	Ras GTPase binding	3.13e-02	1.00e+00	4.978	1	1	14
GO:0031996	thioesterase binding	3.13e-02	1.00e+00	4.978	1	1	14
GO:0048477	oogenesis	3.35e-02	1.00e+00	4.878	1	1	15
GO:0030131	clathrin adaptor complex	3.35e-02	1.00e+00	4.878	1	1	15
GO:0030225	macrophage differentiation	3.35e-02	1.00e+00	4.878	1	1	15
GO:0003951	NAD+ kinase activity	3.35e-02	1.00e+00	4.878	1	1	15
GO:0048821	erythrocyte development	3.35e-02	1.00e+00	4.878	1	2	15
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	3.35e-02	1.00e+00	4.878	1	1	15
GO:0031369	translation initiation factor binding	3.35e-02	1.00e+00	4.878	1	2	15
GO:0051233	spindle midzone	3.35e-02	1.00e+00	4.878	1	2	15
GO:0048854	brain morphogenesis	3.35e-02	1.00e+00	4.878	1	1	15
GO:0030036	actin cytoskeleton organization	3.45e-02	1.00e+00	2.774	2	3	129
GO:0005654	nucleoplasm	3.50e-02	1.00e+00	1.273	6	26	1095
GO:0007405	neuroblast proliferation	3.57e-02	1.00e+00	4.785	1	1	16
GO:0014911	positive regulation of smooth muscle cell migration	3.57e-02	1.00e+00	4.785	1	1	16
GO:0048037	cofactor binding	3.57e-02	1.00e+00	4.785	1	1	16
GO:0019226	transmission of nerve impulse	3.57e-02	1.00e+00	4.785	1	1	16
GO:0000132	establishment of mitotic spindle orientation	3.57e-02	1.00e+00	4.785	1	2	16
GO:0042176	regulation of protein catabolic process	3.57e-02	1.00e+00	4.785	1	4	16
GO:2000811	negative regulation of anoikis	3.57e-02	1.00e+00	4.785	1	1	16
GO:0009615	response to virus	3.60e-02	1.00e+00	2.741	2	4	132
GO:0043274	phospholipase binding	3.79e-02	1.00e+00	4.698	1	1	17
GO:0030742	GTP-dependent protein binding	3.79e-02	1.00e+00	4.698	1	1	17
GO:0003682	chromatin binding	3.95e-02	1.00e+00	1.986	3	4	334
GO:0070064	proline-rich region binding	4.00e-02	1.00e+00	4.615	1	1	18
GO:0045773	positive regulation of axon extension	4.00e-02	1.00e+00	4.615	1	1	18
GO:0031954	positive regulation of protein autophosphorylation	4.00e-02	1.00e+00	4.615	1	1	18
GO:0090316	positive regulation of intracellular protein transport	4.00e-02	1.00e+00	4.615	1	1	18
GO:0005813	centrosome	4.10e-02	1.00e+00	1.965	3	9	339
GO:0008286	insulin receptor signaling pathway	4.21e-02	1.00e+00	2.615	2	4	144
GO:0006259	DNA metabolic process	4.22e-02	1.00e+00	4.537	1	1	19
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	4.22e-02	1.00e+00	4.537	1	1	19
GO:0007088	regulation of mitosis	4.22e-02	1.00e+00	4.537	1	1	19
GO:0045453	bone resorption	4.22e-02	1.00e+00	4.537	1	1	19
GO:0031667	response to nutrient levels	4.22e-02	1.00e+00	4.537	1	1	19
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.33e-02	1.00e+00	1.583	4	9	589
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	4.42e-02	1.00e+00	2.576	2	3	148
GO:0032148	activation of protein kinase B activity	4.44e-02	1.00e+00	4.463	1	1	20
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	4.44e-02	1.00e+00	4.463	1	2	20
GO:0043473	pigmentation	4.44e-02	1.00e+00	4.463	1	2	20
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	4.44e-02	1.00e+00	4.463	1	1	20
GO:0043393	regulation of protein binding	4.44e-02	1.00e+00	4.463	1	2	20
GO:0010628	positive regulation of gene expression	4.48e-02	1.00e+00	2.566	2	4	149
GO:0042981	regulation of apoptotic process	4.59e-02	1.00e+00	2.547	2	7	151
GO:0007369	gastrulation	4.66e-02	1.00e+00	4.393	1	1	21
GO:0046847	filopodium assembly	4.66e-02	1.00e+00	4.393	1	1	21
GO:0009306	protein secretion	4.66e-02	1.00e+00	4.393	1	2	21
GO:0051881	regulation of mitochondrial membrane potential	4.66e-02	1.00e+00	4.393	1	1	21
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	4.87e-02	1.00e+00	4.326	1	1	22
GO:0046686	response to cadmium ion	4.87e-02	1.00e+00	4.326	1	1	22
GO:0001106	RNA polymerase II transcription corepressor activity	4.87e-02	1.00e+00	4.326	1	1	22
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4.87e-02	1.00e+00	4.326	1	1	22
GO:0007052	mitotic spindle organization	4.87e-02	1.00e+00	4.326	1	1	22
GO:0010008	endosome membrane	4.92e-02	1.00e+00	2.490	2	2	157
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	5.09e-02	1.00e+00	4.261	1	1	23
GO:0045787	positive regulation of cell cycle	5.09e-02	1.00e+00	4.261	1	2	23
GO:0002040	sprouting angiogenesis	5.09e-02	1.00e+00	4.261	1	1	23
GO:0051017	actin filament bundle assembly	5.09e-02	1.00e+00	4.261	1	1	23
GO:0001892	embryonic placenta development	5.09e-02	1.00e+00	4.261	1	1	23
GO:0051297	centrosome organization	5.09e-02	1.00e+00	4.261	1	2	23
GO:0005761	mitochondrial ribosome	5.30e-02	1.00e+00	4.200	1	1	24
GO:0007163	establishment or maintenance of cell polarity	5.30e-02	1.00e+00	4.200	1	2	24
GO:0046329	negative regulation of JNK cascade	5.30e-02	1.00e+00	4.200	1	1	24
GO:0051602	response to electrical stimulus	5.30e-02	1.00e+00	4.200	1	1	24
GO:0034220	ion transmembrane transport	5.49e-02	1.00e+00	2.401	2	2	167
GO:0006611	protein export from nucleus	5.52e-02	1.00e+00	4.141	1	1	25
GO:0031519	PcG protein complex	5.52e-02	1.00e+00	4.141	1	1	25
GO:0050715	positive regulation of cytokine secretion	5.52e-02	1.00e+00	4.141	1	1	25
GO:0048705	skeletal system morphogenesis	5.52e-02	1.00e+00	4.141	1	1	25
GO:0045931	positive regulation of mitotic cell cycle	5.73e-02	1.00e+00	4.085	1	2	26
GO:0045859	regulation of protein kinase activity	5.73e-02	1.00e+00	4.085	1	1	26
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	5.73e-02	1.00e+00	4.085	1	1	26
GO:0030148	sphingolipid biosynthetic process	5.73e-02	1.00e+00	4.085	1	1	26
GO:0051149	positive regulation of muscle cell differentiation	5.95e-02	1.00e+00	4.030	1	2	27
GO:0032720	negative regulation of tumor necrosis factor production	5.95e-02	1.00e+00	4.030	1	1	27
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	5.95e-02	1.00e+00	4.030	1	1	27
GO:0031424	keratinization	5.95e-02	1.00e+00	4.030	1	1	27
GO:0001103	RNA polymerase II repressing transcription factor binding	5.95e-02	1.00e+00	4.030	1	1	27
GO:0030331	estrogen receptor binding	5.95e-02	1.00e+00	4.030	1	1	27
GO:0045184	establishment of protein localization	5.95e-02	1.00e+00	4.030	1	2	27
GO:0031069	hair follicle morphogenesis	5.95e-02	1.00e+00	4.030	1	1	27
GO:0032467	positive regulation of cytokinesis	6.16e-02	1.00e+00	3.978	1	1	28
GO:0005875	microtubule associated complex	6.16e-02	1.00e+00	3.978	1	1	28
GO:0007017	microtubule-based process	6.16e-02	1.00e+00	3.978	1	2	28
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	6.16e-02	1.00e+00	3.978	1	1	28
GO:0019904	protein domain specific binding	6.33e-02	1.00e+00	2.285	2	3	181
GO:0031252	cell leading edge	6.38e-02	1.00e+00	3.927	1	3	29
GO:0019005	SCF ubiquitin ligase complex	6.38e-02	1.00e+00	3.927	1	1	29
GO:0034605	cellular response to heat	6.38e-02	1.00e+00	3.927	1	1	29
GO:0072686	mitotic spindle	6.38e-02	1.00e+00	3.927	1	1	29
GO:0006367	transcription initiation from RNA polymerase II promoter	6.51e-02	1.00e+00	2.261	2	5	184
GO:0010977	negative regulation of neuron projection development	6.59e-02	1.00e+00	3.878	1	2	30
GO:0046875	ephrin receptor binding	6.59e-02	1.00e+00	3.878	1	2	30
GO:0042169	SH2 domain binding	6.59e-02	1.00e+00	3.878	1	1	30
GO:0031647	regulation of protein stability	6.59e-02	1.00e+00	3.878	1	1	30
GO:0040018	positive regulation of multicellular organism growth	6.59e-02	1.00e+00	3.878	1	1	30
GO:0070555	response to interleukin-1	6.80e-02	1.00e+00	3.831	1	1	31
GO:0007093	mitotic cell cycle checkpoint	6.80e-02	1.00e+00	3.831	1	2	31
GO:0033572	transferrin transport	7.01e-02	1.00e+00	3.785	1	1	32
GO:0015992	proton transport	7.01e-02	1.00e+00	3.785	1	1	32
GO:0032091	negative regulation of protein binding	7.22e-02	1.00e+00	3.741	1	1	33
GO:0005158	insulin receptor binding	7.22e-02	1.00e+00	3.741	1	2	33
GO:0033077	T cell differentiation in thymus	7.22e-02	1.00e+00	3.741	1	1	33
GO:0048812	neuron projection morphogenesis	7.22e-02	1.00e+00	3.741	1	1	33
GO:0007611	learning or memory	7.43e-02	1.00e+00	3.698	1	2	34
GO:0001890	placenta development	7.43e-02	1.00e+00	3.698	1	1	34
GO:0042692	muscle cell differentiation	7.43e-02	1.00e+00	3.698	1	2	34
GO:0051701	interaction with host	7.43e-02	1.00e+00	3.698	1	1	34
GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway	7.64e-02	1.00e+00	3.656	1	1	35
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	7.64e-02	1.00e+00	3.656	1	1	35
GO:0003924	GTPase activity	7.72e-02	1.00e+00	2.120	2	6	203
GO:0030178	negative regulation of Wnt signaling pathway	7.85e-02	1.00e+00	3.615	1	1	36
GO:0071560	cellular response to transforming growth factor beta stimulus	7.85e-02	1.00e+00	3.615	1	1	36
GO:0016301	kinase activity	8.06e-02	1.00e+00	3.576	1	2	37
GO:0018107	peptidyl-threonine phosphorylation	8.06e-02	1.00e+00	3.576	1	1	37
GO:0032880	regulation of protein localization	8.06e-02	1.00e+00	3.576	1	1	37
GO:0005730	nucleolus	8.10e-02	1.00e+00	0.875	7	36	1684
GO:0001568	blood vessel development	8.27e-02	1.00e+00	3.537	1	2	38
GO:0050681	androgen receptor binding	8.27e-02	1.00e+00	3.537	1	2	38
GO:0097191	extrinsic apoptotic signaling pathway	8.27e-02	1.00e+00	3.537	1	3	38
GO:0045740	positive regulation of DNA replication	8.27e-02	1.00e+00	3.537	1	1	38
GO:0090382	phagosome maturation	8.27e-02	1.00e+00	3.537	1	1	38
GO:0032092	positive regulation of protein binding	8.48e-02	1.00e+00	3.500	1	1	39
GO:0021766	hippocampus development	8.48e-02	1.00e+00	3.500	1	3	39
GO:0042542	response to hydrogen peroxide	8.69e-02	1.00e+00	3.463	1	1	40
GO:0005765	lysosomal membrane	8.72e-02	1.00e+00	2.017	2	2	218
GO:0006184	GTP catabolic process	8.86e-02	1.00e+00	2.004	2	6	220
GO:0070301	cellular response to hydrogen peroxide	8.90e-02	1.00e+00	3.427	1	1	41
GO:0030521	androgen receptor signaling pathway	8.90e-02	1.00e+00	3.427	1	3	41
GO:0045785	positive regulation of cell adhesion	8.90e-02	1.00e+00	3.427	1	1	41
GO:0050885	neuromuscular process controlling balance	8.90e-02	1.00e+00	3.427	1	1	41
GO:0021987	cerebral cortex development	9.10e-02	1.00e+00	3.393	1	1	42
GO:0005902	microvillus	9.10e-02	1.00e+00	3.393	1	1	42
GO:0004715	non-membrane spanning protein tyrosine kinase activity	9.10e-02	1.00e+00	3.393	1	1	42
GO:0004984	olfactory receptor activity	9.10e-02	1.00e+00	3.393	1	1	42
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	9.10e-02	1.00e+00	3.393	1	1	42
GO:0016874	ligase activity	9.14e-02	1.00e+00	1.978	2	2	224
GO:0007286	spermatid development	9.52e-02	1.00e+00	3.326	1	1	44
GO:0005871	kinesin complex	9.52e-02	1.00e+00	3.326	1	1	44
GO:0005080	protein kinase C binding	9.52e-02	1.00e+00	3.326	1	1	44
GO:0034613	cellular protein localization	9.52e-02	1.00e+00	3.326	1	2	44
GO:0019221	cytokine-mediated signaling pathway	9.55e-02	1.00e+00	1.939	2	5	230
GO:0009411	response to UV	9.72e-02	1.00e+00	3.293	1	2	45
GO:0045893	positive regulation of transcription, DNA-templated	9.74e-02	1.00e+00	1.442	3	8	487
GO:0044297	cell body	9.93e-02	1.00e+00	3.261	1	1	46
GO:0043525	positive regulation of neuron apoptotic process	9.93e-02	1.00e+00	3.261	1	2	46
GO:0045727	positive regulation of translation	9.93e-02	1.00e+00	3.261	1	1	46
GO:0021762	substantia nigra development	9.93e-02	1.00e+00	3.261	1	2	46
GO:0043406	positive regulation of MAP kinase activity	1.01e-01	1.00e+00	3.230	1	1	47
GO:0005634	nucleus	1.02e-01	1.00e+00	0.455	15	66	4828
GO:0006950	response to stress	1.03e-01	1.00e+00	3.200	1	1	48
GO:0019003	GDP binding	1.03e-01	1.00e+00	3.200	1	1	48
GO:0005070	SH3/SH2 adaptor activity	1.05e-01	1.00e+00	3.170	1	1	49
GO:0007030	Golgi organization	1.07e-01	1.00e+00	3.141	1	3	50
GO:0090263	positive regulation of canonical Wnt signaling pathway	1.09e-01	1.00e+00	3.113	1	1	51
GO:0030900	forebrain development	1.09e-01	1.00e+00	3.113	1	1	51
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.10e-01	1.00e+00	1.121	4	11	811
GO:0055085	transmembrane transport	1.10e-01	1.00e+00	1.364	3	3	514
GO:0008202	steroid metabolic process	1.11e-01	1.00e+00	3.085	1	1	52
GO:0016042	lipid catabolic process	1.11e-01	1.00e+00	3.085	1	2	52
GO:0006952	defense response	1.14e-01	1.00e+00	3.057	1	1	53
GO:0030175	filopodium	1.14e-01	1.00e+00	3.057	1	2	53
GO:0009612	response to mechanical stimulus	1.16e-01	1.00e+00	3.030	1	1	54
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.16e-01	1.00e+00	3.030	1	1	54
GO:0097193	intrinsic apoptotic signaling pathway	1.18e-01	1.00e+00	3.004	1	2	55
GO:0002039	p53 binding	1.18e-01	1.00e+00	3.004	1	1	55
GO:0000226	microtubule cytoskeleton organization	1.18e-01	1.00e+00	3.004	1	1	55
GO:0046330	positive regulation of JNK cascade	1.18e-01	1.00e+00	3.004	1	1	55
GO:0006281	DNA repair	1.20e-01	1.00e+00	1.741	2	5	264
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	1.22e-01	1.00e+00	2.952	1	1	57
GO:0006879	cellular iron ion homeostasis	1.22e-01	1.00e+00	2.952	1	2	57
GO:0005643	nuclear pore	1.26e-01	1.00e+00	2.902	1	1	59
GO:0005975	carbohydrate metabolic process	1.28e-01	1.00e+00	1.687	2	3	274
GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.30e-01	1.00e+00	2.854	1	1	61
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.31e-01	1.00e+00	2.831	1	1	62
GO:0000151	ubiquitin ligase complex	1.33e-01	1.00e+00	2.808	1	1	63
GO:0005901	caveola	1.33e-01	1.00e+00	2.808	1	1	63
GO:0000776	kinetochore	1.33e-01	1.00e+00	2.808	1	3	63
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.33e-01	1.00e+00	2.808	1	2	63
GO:0006417	regulation of translation	1.33e-01	1.00e+00	2.808	1	4	63
GO:0032869	cellular response to insulin stimulus	1.35e-01	1.00e+00	2.785	1	2	64
GO:0016491	oxidoreductase activity	1.37e-01	1.00e+00	2.763	1	1	65
GO:0019899	enzyme binding	1.38e-01	1.00e+00	1.615	2	5	288
GO:0006915	apoptotic process	1.38e-01	1.00e+00	1.213	3	9	571
GO:0071260	cellular response to mechanical stimulus	1.39e-01	1.00e+00	2.741	1	3	66
GO:0007264	small GTPase mediated signal transduction	1.40e-01	1.00e+00	1.605	2	7	290
GO:0030141	secretory granule	1.41e-01	1.00e+00	2.719	1	2	67
GO:0006665	sphingolipid metabolic process	1.43e-01	1.00e+00	2.698	1	1	68
GO:0035264	multicellular organism growth	1.47e-01	1.00e+00	2.656	1	1	70
GO:0043234	protein complex	1.48e-01	1.00e+00	1.556	2	9	300
GO:0042393	histone binding	1.49e-01	1.00e+00	2.635	1	1	71
GO:0001503	ossification	1.49e-01	1.00e+00	2.635	1	2	71
GO:0000785	chromatin	1.53e-01	1.00e+00	2.595	1	2	73
GO:0042826	histone deacetylase binding	1.55e-01	1.00e+00	2.576	1	1	74
GO:0007265	Ras protein signal transduction	1.57e-01	1.00e+00	2.556	1	3	75
GO:0051897	positive regulation of protein kinase B signaling	1.57e-01	1.00e+00	2.556	1	1	75
GO:0060070	canonical Wnt signaling pathway	1.57e-01	1.00e+00	2.556	1	2	75
GO:0044325	ion channel binding	1.61e-01	1.00e+00	2.518	1	3	77
GO:0007229	integrin-mediated signaling pathway	1.63e-01	1.00e+00	2.500	1	2	78
GO:0019901	protein kinase binding	1.64e-01	1.00e+00	1.463	2	9	320
GO:0010629	negative regulation of gene expression	1.66e-01	1.00e+00	2.463	1	2	80
GO:0031902	late endosome membrane	1.66e-01	1.00e+00	2.463	1	1	80
GO:0007411	axon guidance	1.69e-01	1.00e+00	1.432	2	3	327
GO:0045177	apical part of cell	1.70e-01	1.00e+00	2.427	1	1	82
GO:0004713	protein tyrosine kinase activity	1.70e-01	1.00e+00	2.427	1	1	82
GO:0005525	GTP binding	1.70e-01	1.00e+00	1.427	2	6	328
GO:0008283	cell proliferation	1.72e-01	1.00e+00	1.414	2	4	331
GO:0030336	negative regulation of cell migration	1.72e-01	1.00e+00	2.410	1	2	83
GO:0043231	intracellular membrane-bounded organelle	1.73e-01	1.00e+00	1.410	2	3	332
GO:0005929	cilium	1.74e-01	1.00e+00	2.393	1	2	84
GO:0005179	hormone activity	1.74e-01	1.00e+00	2.393	1	1	84
GO:0005794	Golgi apparatus	1.82e-01	1.00e+00	1.026	3	8	650
GO:0042593	glucose homeostasis	1.83e-01	1.00e+00	2.309	1	1	89
GO:0042384	cilium assembly	1.85e-01	1.00e+00	2.293	1	2	90
GO:0000922	spindle pole	1.87e-01	1.00e+00	2.277	1	5	91
GO:0016337	single organismal cell-cell adhesion	1.89e-01	1.00e+00	2.261	1	2	92
GO:0042470	melanosome	1.89e-01	1.00e+00	2.261	1	2	92
GO:0003723	RNA binding	1.92e-01	1.00e+00	1.313	2	10	355
GO:0005770	late endosome	1.93e-01	1.00e+00	2.230	1	1	94
GO:0001764	neuron migration	1.96e-01	1.00e+00	2.200	1	2	96
GO:0030426	growth cone	1.98e-01	1.00e+00	2.185	1	3	97
GO:0005178	integrin binding	1.98e-01	1.00e+00	2.185	1	1	97
GO:0005739	mitochondrion	2.11e-01	1.00e+00	0.754	4	10	1046
GO:0014069	postsynaptic density	2.14e-01	1.00e+00	2.057	1	3	106
GO:0030496	midbody	2.20e-01	1.00e+00	2.017	1	4	109
GO:0005938	cell cortex	2.20e-01	1.00e+00	2.017	1	1	109
GO:0070374	positive regulation of ERK1 and ERK2 cascade	2.22e-01	1.00e+00	2.004	1	1	110
GO:0005815	microtubule organizing center	2.22e-01	1.00e+00	2.004	1	4	110
GO:0050900	leukocyte migration	2.23e-01	1.00e+00	1.991	1	1	111
GO:0020037	heme binding	2.23e-01	1.00e+00	1.991	1	1	111
GO:0015630	microtubule cytoskeleton	2.25e-01	1.00e+00	1.978	1	4	112
GO:0005635	nuclear envelope	2.32e-01	1.00e+00	1.927	1	2	116
GO:0000139	Golgi membrane	2.36e-01	1.00e+00	1.113	2	7	408
GO:0032496	response to lipopolysaccharide	2.43e-01	1.00e+00	1.854	1	1	122
GO:0051056	regulation of small GTPase mediated signal transduction	2.44e-01	1.00e+00	1.842	1	3	123
GO:0006511	ubiquitin-dependent protein catabolic process	2.51e-01	1.00e+00	1.796	1	3	127
GO:0008201	heparin binding	2.51e-01	1.00e+00	1.796	1	1	127
GO:0046983	protein dimerization activity	2.58e-01	1.00e+00	1.752	1	3	131
GO:0018108	peptidyl-tyrosine phosphorylation	2.61e-01	1.00e+00	1.730	1	1	133
GO:0016055	Wnt signaling pathway	2.75e-01	1.00e+00	1.645	1	3	141
GO:0005911	cell-cell junction	2.77e-01	1.00e+00	1.635	1	2	142
GO:0007596	blood coagulation	2.84e-01	1.00e+00	0.927	2	5	464
GO:0008017	microtubule binding	2.90e-01	1.00e+00	1.556	1	2	150
GO:0046777	protein autophosphorylation	3.03e-01	1.00e+00	1.481	1	1	158
GO:0008022	protein C-terminus binding	3.07e-01	1.00e+00	1.454	1	4	161
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3.18e-01	1.00e+00	1.393	1	4	168
GO:0007420	brain development	3.25e-01	1.00e+00	1.359	1	3	172
GO:0030424	axon	3.25e-01	1.00e+00	1.359	1	4	172
GO:0031965	nuclear membrane	3.31e-01	1.00e+00	1.326	1	2	176
GO:0007049	cell cycle	3.32e-01	1.00e+00	1.317	1	4	177
GO:0048471	perinuclear region of cytoplasm	3.33e-01	1.00e+00	0.754	2	9	523
GO:0004672	protein kinase activity	3.34e-01	1.00e+00	1.309	1	4	178
GO:0031625	ubiquitin protein ligase binding	3.37e-01	1.00e+00	1.293	1	4	180
GO:0044281	small molecule metabolic process	3.38e-01	1.00e+00	0.446	4	16	1295
GO:0005764	lysosome	3.40e-01	1.00e+00	1.277	1	2	182
GO:0004930	G-protein coupled receptor activity	3.56e-01	1.00e+00	1.193	1	1	193
GO:0007165	signal transduction	3.66e-01	1.00e+00	0.478	3	7	950
GO:0030168	platelet activation	3.74e-01	1.00e+00	1.106	1	4	205
GO:0004871	signal transducer activity	3.90e-01	1.00e+00	1.030	1	1	216
GO:0030425	dendrite	4.22e-01	1.00e+00	0.878	1	3	240
GO:0005102	receptor binding	4.58e-01	1.00e+00	0.719	1	2	268
GO:0000166	nucleotide binding	4.63e-01	1.00e+00	0.698	1	2	272
GO:0007283	spermatogenesis	4.68e-01	1.00e+00	0.676	1	2	276
GO:0005886	plasma membrane	4.68e-01	1.00e+00	0.124	7	24	2834
GO:0042493	response to drug	4.83e-01	1.00e+00	0.615	1	2	288
GO:0006351	transcription, DNA-templated	4.90e-01	1.00e+00	0.155	4	17	1585
GO:0016567	protein ubiquitination	4.96e-01	1.00e+00	0.561	1	3	299
GO:0005743	mitochondrial inner membrane	4.97e-01	1.00e+00	0.556	1	1	300
GO:0004674	protein serine/threonine kinase activity	5.11e-01	1.00e+00	0.500	1	6	312
GO:0035556	intracellular signal transduction	5.16e-01	1.00e+00	0.477	1	5	317
GO:0005575	cellular_component	5.22e-01	1.00e+00	0.454	1	2	322
GO:0007275	multicellular organismal development	5.46e-01	1.00e+00	0.359	1	2	344
GO:0007268	synaptic transmission	5.55e-01	1.00e+00	0.321	1	1	353
GO:0015031	protein transport	5.59e-01	1.00e+00	0.305	1	4	357
GO:0007186	G-protein coupled receptor signaling pathway	5.69e-01	1.00e+00	0.265	1	1	367
GO:0008285	negative regulation of cell proliferation	5.69e-01	1.00e+00	0.265	1	3	367
GO:0005524	ATP binding	6.03e-01	1.00e+00	-0.033	3	19	1354
GO:0045892	negative regulation of transcription, DNA-templated	6.23e-01	1.00e+00	0.057	1	2	424
GO:0006366	transcription from RNA polymerase II promoter	6.24e-01	1.00e+00	0.054	1	3	425
GO:0008150	biological_process	6.52e-01	1.00e+00	-0.057	1	3	459
GO:0006468	protein phosphorylation	6.59e-01	1.00e+00	-0.082	1	6	467
GO:0055114	oxidation-reduction process	6.70e-01	1.00e+00	-0.125	1	2	481
GO:0042802	identical protein binding	6.77e-01	1.00e+00	-0.155	1	4	491
GO:0005783	endoplasmic reticulum	7.56e-01	1.00e+00	-0.468	1	6	610
GO:0042803	protein homodimerization activity	7.60e-01	1.00e+00	-0.484	1	4	617
GO:0003700	sequence-specific DNA binding transcription factor activity	8.24e-01	1.00e+00	-0.762	1	9	748
GO:0005615	extracellular space	9.06e-01	1.00e+00	-1.195	1	3	1010
GO:0008270	zinc ion binding	9.18e-01	1.00e+00	-1.274	1	7	1067
GO:0006355	regulation of transcription, DNA-templated	9.25e-01	1.00e+00	-1.324	1	10	1104
GO:0003677	DNA binding	9.59e-01	1.00e+00	-1.615	1	14	1351
GO:0046872	metal ion binding	9.69e-01	1.00e+00	-1.732	1	14	1465
GO:0016021	integral component of membrane	9.98e-01	1.00e+00	-2.493	1	4	2483

Tai-Luciferase

meta-reg-snw-89910

Interacting subnets

Genes (37)

Interactions (91)

Related GO terms (529)