reg-snw-89910

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 4.386 6.32e-21 1.98e-03 2.88e-03
tai-screen-luciferase-reg-snw-89910 subnetwork

Genes (6)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree Transcription factor List-Gonzales GI Tai-Hits
MRPS12 6183 13-5.4215.516307TFYes-
OR1J2 26740 1-3.4294.38612---
[ UBE3B ] 89910 1-1.3124.3866---
COPA 1314 25-9.3955.672170TFYesYes
PAFAH1B1 5048 3-2.5834.58655TFYes-
HSF1 3297 8-4.1795.027138TF-Yes

Interactions (5)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
HSF1 3297 OR1J2 26740 pd > reg.ITFP.txt: no annot
PAFAH1B1 5048 UBE3B 89910 pd > reg.ITFP.txt: no annot
COPA 1314 PAFAH1B1 5048 pd <> reg.ITFP.txt: no annot
HSF1 3297 UBE3B 89910 pd > reg.ITFP.txt: no annot

Related GO terms (113)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0051660establishment of centrosome localization6.14e-041.00e+0010.668111
GO:0051081nuclear envelope disassembly6.14e-041.00e+0010.668111
GO:0000235astral microtubule6.14e-041.00e+0010.668111
GO:0046469platelet activating factor metabolic process6.14e-041.00e+0010.668111
GO:0036035osteoclast development6.14e-041.00e+0010.668111
GO:0090231regulation of spindle checkpoint1.23e-031.00e+009.668112
GO:0045505dynein intermediate chain binding1.23e-031.00e+009.668112
GO:0007143female meiotic division1.84e-031.00e+009.083113
GO:0021540corpus callosum morphogenesis1.84e-031.00e+009.083113
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding1.84e-031.00e+009.083113
GO:0008090retrograde axon cargo transport2.46e-031.00e+008.668114
GO:0030157pancreatic juice secretion2.46e-031.00e+008.668114
GO:0001667ameboidal-type cell migration2.46e-031.00e+008.668114
GO:0034452dynactin binding3.07e-031.00e+008.347115
GO:0007097nuclear migration3.07e-031.00e+008.347125
GO:0031512motile primary cilium3.07e-031.00e+008.347115
GO:0031023microtubule organizing center organization3.07e-031.00e+008.347115
GO:0060136embryonic process involved in female pregnancy3.68e-031.00e+008.083116
GO:0001961positive regulation of cytokine-mediated signaling pathway3.68e-031.00e+008.083116
GO:0017145stem cell division3.68e-031.00e+008.083116
GO:0001675acrosome assembly4.29e-031.00e+007.861117
GO:0032319regulation of Rho GTPase activity4.29e-031.00e+007.861117
GO:0030126COPI vesicle coat4.29e-031.00e+007.861117
GO:0021895cerebral cortex neuron differentiation4.29e-031.00e+007.861117
GO:0045502dynein binding4.91e-031.00e+007.668118
GO:0048854brain morphogenesis5.52e-031.00e+007.499119
GO:0009306protein secretion6.74e-031.00e+007.2091211
GO:0045773positive regulation of axon extension6.74e-031.00e+007.2091111
GO:0045120pronucleus6.74e-031.00e+007.2091111
GO:0021819layer formation in cerebral cortex6.74e-031.00e+007.2091111
GO:0047496vesicle transport along microtubule6.74e-031.00e+007.2091111
GO:0000132establishment of mitotic spindle orientation7.35e-031.00e+007.0831212
GO:0015935small ribosomal subunit7.35e-031.00e+007.0831412
GO:0043274phospholipase binding7.35e-031.00e+007.0831112
GO:0048205COPI coating of Golgi vesicle7.35e-031.00e+007.0831112
GO:0019226transmission of nerve impulse7.96e-031.00e+006.9681113
GO:0007405neuroblast proliferation8.57e-031.00e+006.8611114
GO:0007017microtubule-based process1.04e-021.00e+006.5811117
GO:0006890retrograde vesicle-mediated transport, Golgi to ER1.04e-021.00e+006.5811117
GO:0046329negative regulation of JNK cascade1.16e-021.00e+006.4211119
GO:0001892embryonic placenta development1.22e-021.00e+006.3471120
GO:0032720negative regulation of tumor necrosis factor production1.22e-021.00e+006.3471120
GO:0005761mitochondrial ribosome1.22e-021.00e+006.3471120
GO:0010977negative regulation of neuron projection development1.28e-021.00e+006.2761121
GO:0005875microtubule associated complex1.34e-021.00e+006.2091122
GO:0034605cellular response to heat1.34e-021.00e+006.2091122
GO:0040018positive regulation of multicellular organism growth1.34e-021.00e+006.2091122
GO:0045931positive regulation of mitotic cell cycle1.41e-021.00e+006.1451223
GO:0031252cell leading edge1.47e-021.00e+006.0831224
GO:0007611learning or memory1.47e-021.00e+006.0831124
GO:0051219phosphoprotein binding1.53e-021.00e+006.0251325
GO:0016042lipid catabolic process1.59e-021.00e+005.9681126
GO:0050885neuromuscular process controlling balance1.71e-021.00e+005.8611128
GO:0021987cerebral cortex development1.83e-021.00e+005.7621130
GO:0021766hippocampus development1.89e-021.00e+005.7141331
GO:0005871kinesin complex1.89e-021.00e+005.7141131
GO:0008344adult locomotory behavior2.01e-021.00e+005.6241133
GO:0004984olfactory receptor activity2.07e-021.00e+005.5811134
GO:0050911detection of chemical stimulus involved in sensory perception of smell2.07e-021.00e+005.5811134
GO:0000226microtubule cytoskeleton organization2.19e-021.00e+005.4991136
GO:0006952defense response2.25e-021.00e+005.4591137
GO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic process2.25e-021.00e+005.4591137
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription3.03e-021.00e+005.0251150
GO:0000776kinetochore3.33e-021.00e+004.8871155
GO:0005179hormone activity3.63e-021.00e+004.7621160
GO:0030426growth cone3.87e-021.00e+004.6681364
GO:0001764neuron migration4.05e-021.00e+004.6021267
GO:0005938cell cortex4.64e-021.00e+004.4021177
GO:0005635nuclear envelope4.99e-021.00e+004.2931283
GO:0006886intracellular protein transport5.35e-021.00e+004.1931189
GO:0061024membrane organization5.35e-021.00e+004.1931389
GO:0030036actin cytoskeleton organization5.41e-021.00e+004.1771290
GO:0008201heparin binding5.46e-021.00e+004.1611191
GO:0032496response to lipopolysaccharide5.58e-021.00e+004.1291193
GO:0000086G2/M transition of mitotic cell cycle5.82e-021.00e+004.0691397
GO:0008017microtubule binding5.82e-021.00e+004.0691197
GO:0005198structural molecule activity6.05e-021.00e+004.01011101
GO:0003735structural constituent of ribosome6.51e-021.00e+003.90018109
GO:0004930G-protein coupled receptor activity7.38e-021.00e+003.71411124
GO:0030424axon7.61e-021.00e+003.66814128
GO:0031965nuclear membrane7.73e-021.00e+003.64612130
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding8.42e-021.00e+003.51914142
GO:0016874ligase activity8.64e-021.00e+003.47911146
GO:0007067mitotic nuclear division9.72e-021.00e+003.30215165
GO:0007283spermatogenesis9.89e-021.00e+003.27612168
GO:0043025neuronal cell body1.01e-011.00e+003.25113171
GO:0006412translation1.05e-011.00e+003.193113178
GO:0004842ubiquitin-protein transferase activity1.05e-011.00e+003.18511179
GO:0043234protein complex1.22e-011.00e+002.95418210
GO:0007268synaptic transmission1.25e-011.00e+002.92711214
GO:0005813centrosome1.26e-011.00e+002.90716217
GO:0007186G-protein coupled receptor signaling pathway1.33e-011.00e+002.82911229
GO:0003682chromatin binding1.45e-011.00e+002.69113252
GO:0008285negative regulation of cell proliferation1.59e-011.00e+002.55513277
GO:0006468protein phosphorylation1.71e-011.00e+002.43513301
GO:0000278mitotic cell cycle1.78e-011.00e+002.37419314
GO:0048471perinuclear region of cytoplasm1.94e-011.00e+002.24217344
GO:0005737cytoplasm2.02e-011.00e+000.8913392633
GO:0042803protein homodimerization activity2.36e-011.00e+001.92714428
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.49e-011.00e+001.83616456
GO:0070062extracellular vesicular exosome2.67e-011.00e+000.9882281641
GO:0005829cytosol3.03e-011.00e+000.8652331787
GO:0003700sequence-specific DNA binding transcription factor activity3.08e-011.00e+001.48419582
GO:0045944positive regulation of transcription from RNA polymerase II promoter3.36e-011.00e+001.33818644
GO:0005615extracellular space3.39e-011.00e+001.32212651
GO:0044822poly(A) RNA binding4.01e-011.00e+001.026125799
GO:0005515protein binding5.02e-011.00e+000.2443504124
GO:0006351transcription, DNA-templated5.04e-011.00e+000.5971151076
GO:0016020membrane5.47e-011.00e+000.4311251207
GO:0005730nucleolus5.50e-011.00e+000.4191211217
GO:0016021integral component of membrane6.39e-011.00e+000.093131526
GO:0005634nucleus6.47e-011.00e+000.0042403246
GO:0005886plasma membrane7.02e-011.00e+00-0.1321131784