meta-int-snw-5901

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-1500 tai-screen-luciferase 4.226 2.77e-19 3.65e-03 4.98e-03 9 7
int-snw-5901 tai-screen-luciferase 6.905 2.40e-164 8.38e-09 4.91e-04 14 13
reg-snw-4609 tai-screen-luciferase 4.325 2.79e-20 2.52e-03 3.58e-03 14 8
tai-screen-luciferase-meta-int-snw-5901 subnetwork

Genes (33)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS15 6209 30-5.0407.011116Yes-
RPS2 6187 16-3.2414.22613Yes-
COPA 1314 48-9.3955.672340YesYes
HSF1 3297 46-4.1795.027209-Yes
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RPS16 6217 38-5.4444.880205--
EIF2S2 8894 31-4.3205.672103Yes-
MYC 4609 9-1.9204.32577--
RPS11 6205 44-6.5887.555175Yes-
NME2 4831 24-3.0344.32553--
RPS6 6194 44-5.6038.046217Yes-
MRPS12 6183 35-5.4215.516341Yes-
TLK2 11011 21-4.0115.67214--
YBX1 4904 24-3.0335.516296--
RAN 5901 38-3.8094.325258YesYes
COPB1 1315 39-6.2219.063118YesYes
SERBP1 26135 35-4.6125.516106-Yes
RPS13 6207 43-6.5897.555174Yes-
CDC5L 988 34-3.4195.672155--
THAP11 57215 9-3.6734.3253-Yes
RPS24 6229 46-7.0348.389217Yes-
ODC1 4953 9-2.5034.32512--
RPS9 6203 45-7.1277.555140Yes-
RPS4X 6191 44-6.7477.555263Yes-
PES1 23481 162.9174.22691--
COPZ1 22818 48-8.3019.06313YesYes
ATP6V1D 51382 30-4.1317.286149--
WDR46 9277 31-4.2904.226101YesYes
RPS27A 6233 45-5.6318.389344Yes-
EIF3M 10480 184.4514.88055Yes-
CTNND1 1500 16-2.6514.22653Yes-
ARCN1 372 48-8.2329.063118YesYes

Interactions (97)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
MYC 4609 RPS16 6217 pp -- int.Intact: MI:0914(association);
int.I2D: AGRAVAL_MYC
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
EIF2S2 8894 PES1 23481 pp -- int.I2D: YeastLow
RPS11 6205 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
EIF2S2 8894 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 RPS4X 6191 pp -- int.I2D: YeastHigh, YeastMedium, INTEROLOG
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
YBX1 4904 RPS11 6205 pp -- int.Intact: MI:0914(association)
MYC 4609 COPB2 9276 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS15 6209 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
ARCN1 372 MYC 4609 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct
YBX1 4904 SERBP1 26135 pd > reg.ITFP.txt: no annot
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
MYC 4609 ODC1 4953 pd > reg.TRANSFAC.txt: no annot
NME2 4831 RPS16 6217 pp -- int.Proteinpedia: Mass spectrometry
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS4X 6191 pp -- int.Intact: MI:0914(association)
MRPS12 6183 RPS2 6187 pp -- int.I2D: YeastMedium
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS13 6207 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 PES1 23481 pp -- int.I2D: IntAct_Yeast
MYC 4609 YBX1 4904 pd > reg.TRANSFAC.txt: no annot
MYC 4609 YBX1 4904 pp -- int.Intact: MI:0914(association);
int.I2D: AGRAVAL_MYC
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 PES1 23481 pp -- int.I2D: IntAct_Yeast
MRPS12 6183 RPS15 6209 pp -- int.I2D: YeastMedium
RPS2 6187 RPS15 6209 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS2 6187 RPS9 6203 pp -- int.I2D: BIND_Yeast
RPS24 6229 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CTNND1 1500 MYC 4609 pp -- int.Intact: MI:0914(association);
int.I2D: AGRAVAL_MYC
RPS11 6205 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
MYC 4609 RAN 5901 pd > reg.ITFP.txt: no annot
RPS2 6187 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CTNND1 1500 PES1 23481 pd <> reg.ITFP.txt: no annot
MYC 4609 THAP11 57215 pd < reg.TRANSFAC.txt: no annot
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RPS15 6209 pp -- int.I2D: YeastLow
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RAN 5901 RPS2 6187 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
RPS6 6194 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS24 6229 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
RPS16 6217 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS2 6187 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RAN 5901 WDR46 9277 pp -- int.I2D: YeastLow
RPS15 6209 PES1 23481 pp -- int.I2D: IntAct_Yeast
YBX1 4904 RPS24 6229 pp -- int.Intact: MI:0914(association)
WDR46 9277 PES1 23481 pd <> reg.ITFP.txt: no annot
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)
COPA 1314 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS15 6209 RPS16 6217 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS2 6187 RPS11 6205 pp -- int.I2D: YeastMedium, INTEROLOG
MYC 4609 NME2 4831 pd < reg.TRANSFAC.txt: no annot
RPS6 6194 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 TLK2 11011 pd > reg.ITFP.txt: no annot
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
CDC5L 988 YBX1 4904 pd <> reg.ITFP.txt: no annot
YBX1 4904 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RPS4X 6191 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
CTNND1 1500 RPS2 6187 pd > reg.ITFP.txt: no annot
RPS2 6187 RPS16 6217 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
RPS13 6207 PES1 23481 pp -- int.I2D: IntAct_Yeast
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 RPS16 6217 pp -- int.I2D: BioGrid
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RAN 5901 ATP6V1D 51382 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RAN 5901 PES1 23481 pd < reg.ITFP.txt: no annot
MYC 4609 RPS2 6187 pp -- int.Intact: MI:0914(association);
int.I2D: AGRAVAL_MYC
RPS6 6194 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS13 6207 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS27A 6233 EIF3M 10480 pd < reg.ITFP.txt: no annot
MYC 4609 ATP6V1D 51382 pp -- int.Intact: MI:0914(association);
int.I2D: AGRAVAL_MYC

Related GO terms (370)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit1.54e-192.51e-156.987102139
GO:0006413translational initiation1.31e-172.15e-135.5021227131
GO:0019058viral life cycle2.21e-163.61e-125.5641125115
GO:0019083viral transcription4.31e-167.03e-125.932102281
GO:0006415translational termination9.10e-161.49e-115.829102287
GO:0006414translational elongation1.82e-152.98e-115.733102293
GO:0003735structural constituent of ribosome2.22e-153.62e-115.2701124141
GO:0006614SRP-dependent cotranslational protein targeting to membrane5.81e-159.48e-115.5721022104
GO:0044822poly(A) RNA binding1.09e-141.79e-103.12419421078
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.50e-142.44e-105.4391022114
GO:0006412translation1.63e-142.66e-104.6581229235
GO:0015935small ribosomal subunit5.15e-138.40e-097.4486917
GO:0016020membrane5.04e-128.23e-082.50220481746
GO:0016071mRNA metabolic process1.30e-112.13e-074.4711029223
GO:0010467gene expression1.31e-112.15e-073.3721436669
GO:0048205COPI coating of Golgi vesicle3.13e-115.11e-077.5725613
GO:0030126COPI vesicle coat3.13e-115.11e-077.5725613
GO:0016070RNA metabolic process3.58e-115.85e-074.3241029247
GO:0005829cytosol6.19e-111.01e-062.08622742562
GO:0016032viral process2.87e-104.68e-063.4581237540
GO:0006890retrograde vesicle-mediated transport, Golgi to ER1.27e-092.07e-056.6285625
GO:0044267cellular protein metabolic process1.89e-093.09e-053.4581129495
GO:0042274ribosomal small subunit biogenesis6.78e-091.11e-047.3654612
GO:0061024membrane organization4.20e-076.85e-034.345611146
GO:0005925focal adhesion5.47e-078.93e-033.419823370
GO:0006364rRNA processing1.32e-062.16e-024.6875896
GO:0006891intra-Golgi vesicle-mediated transport5.02e-068.20e-026.4483317
GO:0005840ribosome5.83e-069.51e-025.06741059
GO:0000056ribosomal small subunit export from nucleus1.19e-051.94e-018.365223
GO:0019843rRNA binding2.13e-053.48e-015.7803427
GO:0006886intracellular protein transport2.36e-053.85e-013.83756173
GO:0005515protein binding4.25e-056.94e-010.95424876127
GO:0030529ribonucleoprotein complex7.90e-051.00e+004.11748114
GO:0070062extracellular vesicular exosome1.84e-041.00e+001.46014512516
GO:0005730nucleolus3.07e-041.00e+001.69211361684
GO:0031369translation initiation factor binding4.09e-041.00e+006.0432215
GO:0075733intracellular transport of virus5.29e-041.00e+005.8632317
GO:0036464cytoplasmic ribonucleoprotein granule8.93e-041.00e+005.4912522
GO:0005844polysome1.16e-031.00e+005.3062225
GO:0090096positive regulation of metanephric cap mesenchymal cell proliferation2.02e-031.00e+008.950111
GO:0022605oogenesis stage2.02e-031.00e+008.950111
GO:0018106peptidyl-histidine phosphorylation2.02e-031.00e+008.950111
GO:0033176proton-transporting V-type ATPase complex2.02e-031.00e+008.950111
GO:0002183cytoplasmic translational initiation2.02e-031.00e+008.950111
GO:0021691cerebellar Purkinje cell layer maturation2.02e-031.00e+008.950111
GO:0033387putrescine biosynthetic process from ornithine2.02e-031.00e+008.950111
GO:0004586ornithine decarboxylase activity2.02e-031.00e+008.950111
GO:0004673protein histidine kinase activity2.02e-031.00e+008.950111
GO:0005737cytoplasm2.23e-031.00e+000.99316653976
GO:0005198structural molecule activity3.99e-031.00e+003.22235159
GO:0044346fibroblast apoptotic process4.04e-031.00e+007.950112
GO:0071987WD40-repeat domain binding4.04e-031.00e+007.950112
GO:0002176male germ cell proliferation4.04e-031.00e+007.950112
GO:0000466maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.04e-031.00e+007.950112
GO:0072422signal transduction involved in DNA damage checkpoint4.04e-031.00e+007.950112
GO:0002762negative regulation of myeloid leukocyte differentiation4.04e-031.00e+007.950112
GO:0001672regulation of chromatin assembly or disassembly4.04e-031.00e+007.950112
GO:0003743translation initiation factor activity4.39e-031.00e+004.3352549
GO:0035690cellular response to drug4.57e-031.00e+004.3062350
GO:0050679positive regulation of epithelial cell proliferation5.31e-031.00e+004.1952254
GO:0005654nucleoplasm5.49e-031.00e+001.6617261095
GO:0006879cellular iron ion homeostasis5.90e-031.00e+004.1172257
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding6.05e-031.00e+007.365113
GO:0070545PeBoW complex6.05e-031.00e+007.365113
GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)6.05e-031.00e+007.365113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity6.05e-031.00e+007.365113
GO:0005850eukaryotic translation initiation factor 2 complex6.05e-031.00e+007.365113
GO:0051154negative regulation of striated muscle cell differentiation6.05e-031.00e+007.365113
GO:0032204regulation of telomere maintenance6.05e-031.00e+007.365113
GO:0030687preribosome, large subunit precursor6.05e-031.00e+007.365113
GO:0008284positive regulation of cell proliferation7.73e-031.00e+002.33547392
GO:0005882intermediate filament7.84e-031.00e+003.9062366
GO:0007000nucleolus organization8.06e-031.00e+006.950124
GO:0045682regulation of epidermis development8.06e-031.00e+006.950114
GO:0045656negative regulation of monocyte differentiation8.06e-031.00e+006.950114
GO:0000055ribosomal large subunit export from nucleus8.06e-031.00e+006.950114
GO:0090231regulation of spindle checkpoint8.06e-031.00e+006.950114
GO:0003697single-stranded DNA binding8.55e-031.00e+003.8422469
GO:0003729mRNA binding9.53e-031.00e+003.7602373
GO:0070934CRD-mediated mRNA stabilization1.01e-021.00e+006.628115
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.01e-021.00e+006.628135
GO:0051782negative regulation of cell division1.01e-021.00e+006.628115
GO:0033119negative regulation of RNA splicing1.01e-021.00e+006.628125
GO:0043066negative regulation of apoptotic process1.09e-021.00e+002.192414433
GO:0007067mitotic nuclear division1.12e-021.00e+002.68337231
GO:0007143female meiotic division1.21e-021.00e+006.365116
GO:0019215intermediate filament binding1.21e-021.00e+006.365116
GO:0002309T cell proliferation involved in immune response1.21e-021.00e+006.365116
GO:0045182translation regulator activity1.21e-021.00e+006.365126
GO:0032873negative regulation of stress-activated MAPK cascade1.21e-021.00e+006.365116
GO:0070937CRD-mediated mRNA stability complex1.21e-021.00e+006.365116
GO:0000974Prp19 complex1.21e-021.00e+006.365116
GO:0051347positive regulation of transferase activity1.21e-021.00e+006.365116
GO:0071204histone pre-mRNA 3'end processing complex1.21e-021.00e+006.365116
GO:0006924activation-induced cell death of T cells1.21e-021.00e+006.365126
GO:0050658RNA transport1.41e-021.00e+006.143117
GO:0061512protein localization to cilium1.41e-021.00e+006.143117
GO:0000028ribosomal small subunit assembly1.41e-021.00e+006.143137
GO:0034101erythrocyte homeostasis1.41e-021.00e+006.143117
GO:2001022positive regulation of response to DNA damage stimulus1.41e-021.00e+006.143117
GO:0009142nucleoside triphosphate biosynthetic process1.41e-021.00e+006.143117
GO:0030157pancreatic juice secretion1.41e-021.00e+006.143117
GO:0060136embryonic process involved in female pregnancy1.41e-021.00e+006.143117
GO:0071541eukaryotic translation initiation factor 3 complex, eIF3m1.41e-021.00e+006.143117
GO:0000930gamma-tubulin complex1.41e-021.00e+006.143117
GO:0001649osteoblast differentiation1.57e-021.00e+003.3802395
GO:0006183GTP biosynthetic process1.61e-021.00e+005.950118
GO:0005634nucleus1.69e-021.00e+000.71316664828
GO:0014075response to amine1.81e-021.00e+005.780119
GO:0005915zonula adherens1.81e-021.00e+005.780119
GO:0006228UTP biosynthetic process1.81e-021.00e+005.780119
GO:0006241CTP biosynthetic process1.81e-021.00e+005.780119
GO:0045618positive regulation of keratinocyte differentiation2.00e-021.00e+005.6281110
GO:0005798Golgi-associated vesicle2.00e-021.00e+005.6281110
GO:0048471perinuclear region of cytoplasm2.04e-021.00e+001.91949523
GO:0045120pronucleus2.20e-021.00e+005.4911111
GO:2000573positive regulation of DNA biosynthetic process2.20e-021.00e+005.4911211
GO:0043234protein complex2.23e-021.00e+002.30639300
GO:0007051spindle organization2.40e-021.00e+005.3651112
GO:0019082viral protein processing2.40e-021.00e+005.3651212
GO:0042273ribosomal large subunit biogenesis2.60e-021.00e+005.2501113
GO:0031929TOR signaling2.60e-021.00e+005.2501113
GO:0032479regulation of type I interferon production2.60e-021.00e+005.2501213
GO:0043488regulation of mRNA stability2.60e-021.00e+005.2501113
GO:0005662DNA replication factor A complex2.60e-021.00e+005.2501113
GO:0071398cellular response to fatty acid2.60e-021.00e+005.2501213
GO:0033290eukaryotic 48S preinitiation complex2.60e-021.00e+005.2501113
GO:0007219Notch signaling pathway2.63e-021.00e+002.98424125
GO:0019901protein kinase binding2.64e-021.00e+002.21339320
GO:0035371microtubule plus-end2.79e-021.00e+005.1431114
GO:0071480cellular response to gamma radiation2.79e-021.00e+005.1431114
GO:0016282eukaryotic 43S preinitiation complex2.79e-021.00e+005.1431114
GO:0006165nucleoside diphosphate phosphorylation2.79e-021.00e+005.1431114
GO:0070848response to growth factor2.79e-021.00e+005.1431114
GO:0015671oxygen transport2.79e-021.00e+005.1431114
GO:0006595polyamine metabolic process2.79e-021.00e+005.1431114
GO:0030027lamellipodium2.83e-021.00e+002.92823130
GO:0007179transforming growth factor beta receptor signaling pathway2.83e-021.00e+002.92824130
GO:0043231intracellular membrane-bounded organelle2.90e-021.00e+002.16033332
GO:0003682chromatin binding2.95e-021.00e+002.15134334
GO:0004550nucleoside diphosphate kinase activity2.99e-021.00e+005.0431115
GO:0048821erythrocyte development2.99e-021.00e+005.0431215
GO:0005852eukaryotic translation initiation factor 3 complex2.99e-021.00e+005.0431115
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process2.99e-021.00e+005.0431115
GO:0030131clathrin adaptor complex2.99e-021.00e+005.0431115
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.00e-021.00e+001.74849589
GO:0005813centrosome3.06e-021.00e+002.13039339
GO:0000086G2/M transition of mitotic cell cycle3.12e-021.00e+002.85226137
GO:0042176regulation of protein catabolic process3.19e-021.00e+004.9501416
GO:0051276chromosome organization3.19e-021.00e+004.9501116
GO:0033365protein localization to organelle3.38e-021.00e+004.8631117
GO:0001731formation of translation preinitiation complex3.38e-021.00e+004.8631117
GO:0019068virion assembly3.38e-021.00e+004.8631217
GO:0008286insulin receptor signaling pathway3.41e-021.00e+002.78024144
GO:0003723RNA binding3.44e-021.00e+002.063310355
GO:0010507negative regulation of autophagy3.58e-021.00e+004.7801118
GO:0015949nucleobase-containing small molecule interconversion3.58e-021.00e+004.7801118
GO:0043015gamma-tubulin binding3.58e-021.00e+004.7801218
GO:0006351transcription, DNA-templated3.62e-021.00e+001.1277171585
GO:0000082G1/S transition of mitotic cell cycle3.68e-021.00e+002.721211150
GO:0042981regulation of apoptotic process3.72e-021.00e+002.71227151
GO:0006259DNA metabolic process3.77e-021.00e+004.7021119
GO:0017134fibroblast growth factor binding3.77e-021.00e+004.7021219
GO:0043473pigmentation3.97e-021.00e+004.6281220
GO:0006974cellular response to DNA damage stimulus4.04e-021.00e+002.64623158
GO:0043021ribonucleoprotein complex binding4.16e-021.00e+004.5581121
GO:0007369gastrulation4.16e-021.00e+004.5581121
GO:0000793condensed chromosome4.16e-021.00e+004.5581221
GO:0005689U12-type spliceosomal complex4.16e-021.00e+004.5581221
GO:0007220Notch receptor processing4.36e-021.00e+004.4911222
GO:0033574response to testosterone4.36e-021.00e+004.4911122
GO:0007052mitotic spindle organization4.36e-021.00e+004.4911122
GO:0000398mRNA splicing, via spliceosome4.37e-021.00e+002.58422165
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding4.52e-021.00e+002.55824168
GO:0001892embryonic placenta development4.55e-021.00e+004.4261123
GO:0051297centrosome organization4.55e-021.00e+004.4261223
GO:0071944cell periphery4.55e-021.00e+004.4261123
GO:0008135translation factor activity, nucleic acid binding4.74e-021.00e+004.3651424
GO:0005761mitochondrial ribosome4.74e-021.00e+004.3651124
GO:0048147negative regulation of fibroblast proliferation4.74e-021.00e+004.3651124
GO:0006611protein export from nucleus4.94e-021.00e+004.3061125
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway4.94e-021.00e+004.3061225
GO:0045296cadherin binding4.94e-021.00e+004.3061125
GO:0005978glycogen biosynthetic process5.13e-021.00e+004.2501226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia5.13e-021.00e+004.2501226
GO:0006367transcription initiation from RNA polymerase II promoter5.31e-021.00e+002.42625184
GO:0032720negative regulation of tumor necrosis factor production5.32e-021.00e+004.1951127
GO:0042626ATPase activity, coupled to transmembrane movement of substances5.51e-021.00e+004.1431128
GO:0010332response to gamma radiation5.71e-021.00e+004.0921229
GO:0003730mRNA 3'-UTR binding5.71e-021.00e+004.0921129
GO:0034605cellular response to heat5.71e-021.00e+004.0921129
GO:0040018positive regulation of multicellular organism growth5.90e-021.00e+004.0431130
GO:0070491repressing transcription factor binding5.90e-021.00e+004.0431130
GO:0010494cytoplasmic stress granule5.90e-021.00e+004.0431230
GO:0045171intercellular bridge6.09e-021.00e+003.9961231
GO:0007093mitotic cell cycle checkpoint6.09e-021.00e+003.9961231
GO:0003700sequence-specific DNA binding transcription factor activity6.25e-021.00e+001.40349748
GO:0070888E-box binding6.28e-021.00e+003.9501132
GO:0015992proton transport6.28e-021.00e+003.9501132
GO:0032480negative regulation of type I interferon production6.28e-021.00e+003.9501232
GO:0034644cellular response to UV6.28e-021.00e+003.9501132
GO:0033572transferrin transport6.28e-021.00e+003.9501132
GO:0002053positive regulation of mesenchymal cell proliferation6.47e-021.00e+003.9061133
GO:0033077T cell differentiation in thymus6.47e-021.00e+003.9061133
GO:0001890placenta development6.66e-021.00e+003.8631134
GO:0051701interaction with host6.66e-021.00e+003.8631134
GO:0001701in utero embryonic development6.71e-021.00e+002.23622210
GO:0071333cellular response to glucose stimulus6.85e-021.00e+003.8211235
GO:0006355regulation of transcription, DNA-templated6.89e-021.00e+001.1635101104
GO:0034332adherens junction organization7.03e-021.00e+003.7801436
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process7.03e-021.00e+003.7801236
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway7.03e-021.00e+003.7801336
GO:0006446regulation of translational initiation7.03e-021.00e+003.7801236
GO:0050681androgen receptor binding7.41e-021.00e+003.7021238
GO:0090382phagosome maturation7.41e-021.00e+003.7021138
GO:0021766hippocampus development7.60e-021.00e+003.6651339
GO:0051781positive regulation of cell division7.60e-021.00e+003.6651139
GO:0032092positive regulation of protein binding7.60e-021.00e+003.6651139
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.92e-021.00e+001.286411811
GO:0007249I-kappaB kinase/NF-kappaB signaling7.97e-021.00e+003.5921441
GO:0030521androgen receptor signaling pathway7.97e-021.00e+003.5921341
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway8.35e-021.00e+003.5241243
GO:0001658branching involved in ureteric bud morphogenesis8.35e-021.00e+003.5241143
GO:0048146positive regulation of fibroblast proliferation8.53e-021.00e+003.4911144
GO:0007286spermatid development8.53e-021.00e+003.4911144
GO:0051591response to cAMP8.72e-021.00e+003.4581145
GO:0044297cell body8.90e-021.00e+003.4261146
GO:0045727positive regulation of translation8.90e-021.00e+003.4261146
GO:0008344adult locomotory behavior9.09e-021.00e+003.3951247
GO:0019003GDP binding9.27e-021.00e+003.3651148
GO:0006521regulation of cellular amino acid metabolic process9.64e-021.00e+003.3061550
GO:0007254JNK cascade9.82e-021.00e+003.2781351
GO:0006952defense response1.02e-011.00e+003.2221153
GO:0030666endocytic vesicle membrane1.04e-011.00e+003.1951254
GO:0051403stress-activated MAPK cascade1.04e-011.00e+003.1951454
GO:0043065positive regulation of apoptotic process1.06e-011.00e+001.85226274
GO:0005793endoplasmic reticulum-Golgi intermediate compartment1.09e-011.00e+003.1171157
GO:0016197endosomal transport1.11e-011.00e+003.0921358
GO:0045216cell-cell junction organization1.13e-011.00e+003.0671259
GO:0005643nuclear pore1.13e-011.00e+003.0671159
GO:0010976positive regulation of neuron projection development1.15e-011.00e+003.0431260
GO:0032481positive regulation of type I interferon production1.16e-011.00e+003.0191361
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.18e-011.00e+002.9961162
GO:0006417regulation of translation1.20e-011.00e+002.9731463
GO:0007059chromosome segregation1.22e-011.00e+002.9501364
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.22e-011.00e+002.9501264
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.23e-011.00e+002.9281665
GO:0034166toll-like receptor 10 signaling pathway1.23e-011.00e+002.9281565
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.23e-011.00e+002.9281665
GO:0034146toll-like receptor 5 signaling pathway1.23e-011.00e+002.9281565
GO:0006338chromatin remodeling1.29e-011.00e+002.8631268
GO:0018105peptidyl-serine phosphorylation1.31e-011.00e+002.8421569
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.32e-011.00e+002.8211870
GO:0003677DNA binding1.33e-011.00e+000.8725141351
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway1.34e-011.00e+002.8001571
GO:0034329cell junction assembly1.34e-011.00e+002.8001271
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway1.34e-011.00e+002.8001571
GO:0000165MAPK cascade1.36e-011.00e+002.7801272
GO:0034162toll-like receptor 9 signaling pathway1.36e-011.00e+002.7801572
GO:0010468regulation of gene expression1.36e-011.00e+002.7801172
GO:0034134toll-like receptor 2 signaling pathway1.38e-011.00e+002.7601573
GO:0005575cellular_component1.38e-011.00e+001.61922322
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.38e-011.00e+002.7601673
GO:0000785chromatin1.38e-011.00e+002.7601273
GO:0055086nucleobase-containing small molecule metabolic process1.38e-011.00e+002.7601273
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.39e-011.00e+002.7411874
GO:0060070canonical Wnt signaling pathway1.41e-011.00e+002.7211275
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding1.41e-011.00e+002.7211175
GO:0035666TRIF-dependent toll-like receptor signaling pathway1.43e-011.00e+002.7021576
GO:0008584male gonad development1.45e-011.00e+002.6831177
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.45e-011.00e+002.6831677
GO:0007229integrin-mediated signaling pathway1.46e-011.00e+002.6651278
GO:0002756MyD88-independent toll-like receptor signaling pathway1.46e-011.00e+002.6651578
GO:0001822kidney development1.48e-011.00e+002.6461279
GO:0071013catalytic step 2 spliceosome1.48e-011.00e+002.6461179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.48e-011.00e+002.6461879
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.50e-011.00e+002.6281580
GO:0034138toll-like receptor 3 signaling pathway1.50e-011.00e+002.6281580
GO:0010629negative regulation of gene expression1.50e-011.00e+002.6281280
GO:0001726ruffle1.53e-011.00e+002.5921182
GO:0043197dendritic spine1.55e-011.00e+002.5751283
GO:0005179hormone activity1.57e-011.00e+002.5581184
GO:0005929cilium1.57e-011.00e+002.5581284
GO:0050852T cell receptor signaling pathway1.64e-011.00e+002.4911288
GO:0090090negative regulation of canonical Wnt signaling pathway1.64e-011.00e+002.4911388
GO:0042593glucose homeostasis1.65e-011.00e+002.4741189
GO:0000187activation of MAPK activity1.67e-011.00e+002.4581390
GO:0042384cilium assembly1.67e-011.00e+002.4581290
GO:0000922spindle pole1.69e-011.00e+002.4421591
GO:0003690double-stranded DNA binding1.69e-011.00e+002.4421291
GO:0016337single organismal cell-cell adhesion1.70e-011.00e+002.4261292
GO:0042470melanosome1.70e-011.00e+002.4261292
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.74e-011.00e+002.3951794
GO:0034142toll-like receptor 4 signaling pathway1.77e-011.00e+002.3651596
GO:0030426growth cone1.79e-011.00e+002.3501397
GO:0071456cellular response to hypoxia1.80e-011.00e+002.3351398
GO:0016568chromatin modification1.82e-011.00e+002.3211299
GO:0006112energy reserve metabolic process1.82e-011.00e+002.3211299
GO:0007155cell adhesion1.82e-011.00e+001.36523384
GO:0051726regulation of cell cycle1.87e-011.00e+002.27812102
GO:0000278mitotic cell cycle1.92e-011.00e+001.313216398
GO:0030496midbody1.99e-011.00e+002.18214109
GO:0002224toll-like receptor signaling pathway1.99e-011.00e+002.18215109
GO:0015630microtubule cytoskeleton2.03e-011.00e+002.14314112
GO:0097190apoptotic signaling pathway2.10e-011.00e+002.09213116
GO:0000209protein polyubiquitination2.10e-011.00e+002.09217116
GO:0006006glucose metabolic process2.15e-011.00e+002.05514119
GO:0032496response to lipopolysaccharide2.20e-011.00e+002.01911122
GO:0051092positive regulation of NF-kappaB transcription factor activity2.24e-011.00e+001.98413125
GO:0007050cell cycle arrest2.26e-011.00e+001.97312126
GO:0046983protein dimerization activity2.34e-011.00e+001.91713131
GO:0009615response to virus2.35e-011.00e+001.90614132
GO:0006468protein phosphorylation2.43e-011.00e+001.08326467
GO:0045202synapse2.48e-011.00e+001.82111140
GO:0016055Wnt signaling pathway2.49e-011.00e+001.81013141
GO:0005911cell-cell junction2.51e-011.00e+001.80012142
GO:0045893positive regulation of transcription, DNA-templated2.58e-011.00e+001.02228487
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling2.60e-011.00e+001.74113148
GO:0044281small molecule metabolic process2.64e-011.00e+000.6114161295
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2.64e-011.00e+001.71212151
GO:0010008endosome membrane2.73e-011.00e+001.65512157
GO:0008543fibroblast growth factor receptor signaling pathway2.76e-011.00e+001.63713159
GO:0055085transmembrane transport2.79e-011.00e+000.94423514
GO:0034220ion transmembrane transport2.88e-011.00e+001.56612167
GO:0038095Fc-epsilon receptor signaling pathway2.94e-011.00e+001.53213171
GO:0007420brain development2.95e-011.00e+001.52413172
GO:0016607nuclear speck3.00e-011.00e+001.49912175
GO:0031965nuclear membrane3.01e-011.00e+001.49112176
GO:0034641cellular nitrogen compound metabolic process3.02e-011.00e+001.48215177
GO:0007049cell cycle3.02e-011.00e+001.48214177
GO:0019904protein domain specific binding3.08e-011.00e+001.45013181
GO:0032403protein complex binding3.14e-011.00e+001.41912185
GO:0007173epidermal growth factor receptor signaling pathway3.22e-011.00e+001.37315191
GO:0003924GTPase activity3.39e-011.00e+001.28516203
GO:0005765lysosomal membrane3.59e-011.00e+001.18212218
GO:0006184GTP catabolic process3.61e-011.00e+001.16916220
GO:0019221cytokine-mediated signaling pathway3.74e-011.00e+001.10515230
GO:0008380RNA splicing3.77e-011.00e+001.09215232
GO:0005794Golgi apparatus3.81e-011.00e+000.60628650
GO:0003713transcription coactivator activity3.86e-011.00e+001.04916239
GO:0030425dendrite3.87e-011.00e+001.04313240
GO:0008134transcription factor binding3.94e-011.00e+001.00815246
GO:0006281DNA repair4.16e-011.00e+000.90615264
GO:0005102receptor binding4.21e-011.00e+000.88412268
GO:0000166nucleotide binding4.26e-011.00e+000.86312272
GO:0048011neurotrophin TRK receptor signaling pathway4.27e-011.00e+000.85715273
GO:0005975carbohydrate metabolic process4.28e-011.00e+000.85213274
GO:0007283spermatogenesis4.31e-011.00e+000.84212276
GO:0042493response to drug4.45e-011.00e+000.78012288
GO:0019899enzyme binding4.45e-011.00e+000.78015288
GO:0007264small GTPase mediated signal transduction4.47e-011.00e+000.77017290
GO:0004674protein serine/threonine kinase activity4.71e-011.00e+000.66516312
GO:0035556intracellular signal transduction4.77e-011.00e+000.64215317
GO:0005525GTP binding4.89e-011.00e+000.59216328
GO:0008283cell proliferation4.92e-011.00e+000.57914331
GO:0007275multicellular organismal development5.05e-011.00e+000.52412344
GO:0008285negative regulation of cell proliferation5.28e-011.00e+000.43013367
GO:0000139Golgi membrane5.67e-011.00e+000.27817408
GO:0046872metal ion binding5.79e-011.00e+000.0183141465
GO:0006366transcription from RNA polymerase II promoter5.82e-011.00e+000.21913425
GO:0008150biological_process6.10e-011.00e+000.10813459
GO:0006915apoptotic process6.92e-011.00e+00-0.20719571
GO:0005783endoplasmic reticulum7.16e-011.00e+00-0.30316610
GO:0045087innate immune response7.19e-011.00e+00-0.317111616
GO:0042803protein homodimerization activity7.20e-011.00e+00-0.31914617
GO:0005524ATP binding7.72e-011.00e+00-0.4532191354
GO:0005886plasma membrane8.49e-011.00e+00-0.5194242834
GO:0007165signal transduction8.62e-011.00e+00-0.94217950
GO:0005615extracellular space8.79e-011.00e+00-1.030131010
GO:0008270zinc ion binding8.93e-011.00e+00-1.109171067