int-snw-5901

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	6.905	2.40e-164	8.38e-09	4.91e-04

tai-screen-luciferase-int-snw-5901 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
RPS4X	6191	18	-6.747	7.555	263	Yes	-
RPS15	6209	7	-5.040	7.011	116	Yes	-
COPZ1	22818	32	-8.301	9.063	13	Yes	Yes
ATP6V1D	51382	8	-4.131	7.286	149	-	-
WDR46	9277	3	-4.290	7.486	87	Yes	Yes
COPA	1314	32	-9.395	9.063	170	Yes	Yes
RPS11	6205	17	-6.588	7.555	175	Yes	-
RPS24	6229	21	-7.034	8.389	217	Yes	-
[ RAN ]	5901	4	-3.809	6.905	175	Yes	Yes
RPS9	6203	18	-7.127	7.555	140	Yes	-
ARCN1	372	32	-8.232	9.063	118	Yes	Yes
COPB2	9276	32	-13.168	9.063	41	Yes	Yes
COPB1	1315	22	-6.221	9.063	118	Yes	Yes
RPS13	6207	17	-6.589	7.555	174	Yes	-

Interactions (32)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPS9	6203	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS9	6203	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	RPS11	6205	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS4X	6191	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPB1	1315	pp	--	int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS9	6203	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	RAN	5901	pp	--	int.I2D: YeastLow
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
RPS4X	6191	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
RPS11	6205	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS15	6209	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	WDR46	9277	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS11	6205	RPS15	6209	pp	--	int.I2D: INTEROLOG, YeastMedium
COPA	1314	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS4X	6191	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS4X	6191	RPS9	6203	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	ATP6V1D	51382	pp	--	int.I2D: YeastLow
ARCN1	372	COPB1	1315	pp	--	int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo
RPS11	6205	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	RPS15	6209	pp	--	int.I2D: YeastLow
RPS15	6209	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS24	6229	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
RAN	5901	WDR46	9277	pp	--	int.I2D: YeastLow
RPS4X	6191	RPS15	6209	pp	--	int.I2D: INTEROLOG, YeastMedium
COPB1	1315	COPB2	9276	pp	--	int.I2D: BioGrid
COPB1	1315	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association)

Related GO terms (108)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0030126	COPI vesicle coat	3.04e-13	4.38e-09	8.746	5	7	12
GO:0048205	COPI coating of Golgi vesicle	4.94e-13	7.12e-09	8.630	5	8	13
GO:0022627	cytosolic small ribosomal subunit	7.72e-13	1.11e-08	7.308	6	20	39
GO:0019058	viral life cycle	5.58e-12	8.05e-08	5.971	7	23	115
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	2.03e-11	2.92e-07	7.687	5	8	25
GO:0019083	viral transcription	7.53e-11	1.09e-06	6.254	6	20	81
GO:0006415	translational termination	1.17e-10	1.68e-06	6.151	6	20	87
GO:0006414	translational elongation	1.76e-10	2.54e-06	6.055	6	20	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.48e-10	5.02e-06	5.893	6	20	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.09e-10	8.78e-06	5.761	6	20	114
GO:0006413	translational initiation	1.42e-09	2.04e-05	5.560	6	21	131
GO:0005829	cytosol	1.43e-09	2.06e-05	2.424	13	61	2496
GO:0003735	structural constituent of ribosome	1.86e-09	2.68e-05	5.496	6	22	137
GO:0016032	viral process	8.27e-09	1.19e-04	3.948	8	33	534
GO:0016020	membrane	1.36e-08	1.96e-04	2.753	11	41	1681
GO:0016071	mRNA metabolic process	3.46e-08	4.99e-04	4.793	6	25	223
GO:0006412	translation	4.16e-08	6.00e-04	4.748	6	23	230
GO:0016070	RNA metabolic process	6.36e-08	9.17e-04	4.645	6	25	247
GO:0044822	poly(A) RNA binding	8.37e-08	1.21e-03	3.134	9	32	1056
GO:0061024	membrane organization	1.78e-07	2.57e-03	5.151	5	12	145
GO:0005840	ribosome	2.29e-07	3.30e-03	6.151	4	8	58
GO:0006886	intracellular protein transport	4.06e-07	5.85e-03	4.913	5	7	171
GO:0006891	intra-Golgi vesicle-mediated transport	4.91e-07	7.08e-03	7.506	3	4	17
GO:0010467	gene expression	1.16e-06	1.67e-02	3.430	7	29	669
GO:0019843	rRNA binding	2.10e-06	3.03e-02	6.839	3	4	27
GO:0000056	ribosomal small subunit export from nucleus	2.62e-06	3.78e-02	9.424	2	2	3
GO:0044267	cellular protein metabolic process	2.93e-06	4.22e-02	3.705	6	23	474
GO:0005925	focal adhesion	1.70e-05	2.45e-01	3.815	5	19	366
GO:0042274	ribosomal small subunit biogenesis	5.74e-05	8.28e-01	7.424	2	6	12
GO:0015935	small ribosomal subunit	1.18e-04	1.00e+00	6.921	2	9	17
GO:0005198	structural molecule activity	3.69e-04	1.00e+00	4.365	3	6	150
GO:0033176	proton-transporting V-type ATPase complex	9.71e-04	1.00e+00	10.009	1	1	1
GO:0021691	cerebellar Purkinje cell layer maturation	9.71e-04	1.00e+00	10.009	1	1	1
GO:0001649	osteoblast differentiation	3.48e-03	1.00e+00	4.485	2	3	92
GO:0006364	rRNA processing	3.63e-03	1.00e+00	4.454	2	7	94
GO:0000055	ribosomal large subunit export from nucleus	3.88e-03	1.00e+00	8.009	1	1	4
GO:0070062	extracellular vesicular exosome	4.05e-03	1.00e+00	1.587	7	40	2400
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.84e-03	1.00e+00	7.687	1	3	5
GO:0033119	negative regulation of RNA splicing	4.84e-03	1.00e+00	7.687	1	2	5
GO:0030529	ribonucleoprotein complex	5.12e-03	1.00e+00	4.201	2	7	112
GO:0045182	translation regulator activity	5.81e-03	1.00e+00	7.424	1	2	6
GO:0061512	protein localization to cilium	5.81e-03	1.00e+00	7.424	1	1	6
GO:0034101	erythrocyte homeostasis	6.78e-03	1.00e+00	7.201	1	1	7
GO:0030157	pancreatic juice secretion	6.78e-03	1.00e+00	7.201	1	1	7
GO:0005798	Golgi-associated vesicle	9.67e-03	1.00e+00	6.687	1	1	10
GO:0030131	clathrin adaptor complex	1.35e-02	1.00e+00	6.201	1	2	14
GO:0031369	translation initiation factor binding	1.45e-02	1.00e+00	6.102	1	1	15
GO:0075733	intracellular transport of virus	1.64e-02	1.00e+00	5.921	1	3	17
GO:0006259	DNA metabolic process	1.83e-02	1.00e+00	5.761	1	1	19
GO:0043473	pigmentation	1.92e-02	1.00e+00	5.687	1	1	20
GO:0036464	cytoplasmic ribonucleoprotein granule	2.12e-02	1.00e+00	5.549	1	3	22
GO:0007052	mitotic spindle organization	2.12e-02	1.00e+00	5.549	1	1	22
GO:0005844	polysome	2.21e-02	1.00e+00	5.485	1	2	23
GO:0006611	protein export from nucleus	2.40e-02	1.00e+00	5.365	1	1	25
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	2.50e-02	1.00e+00	5.308	1	1	26
GO:0015992	proton transport	2.78e-02	1.00e+00	5.151	1	1	29
GO:0033572	transferrin transport	2.87e-02	1.00e+00	5.102	1	1	30
GO:0051701	interaction with host	3.06e-02	1.00e+00	5.009	1	1	32
GO:0090382	phagosome maturation	3.44e-02	1.00e+00	4.839	1	1	36
GO:0032092	positive regulation of protein binding	3.63e-02	1.00e+00	4.761	1	1	38
GO:0050681	androgen receptor binding	3.63e-02	1.00e+00	4.761	1	1	38
GO:0043231	intracellular membrane-bounded organelle	3.70e-02	1.00e+00	2.696	2	5	318
GO:0007286	spermatid development	3.91e-02	1.00e+00	4.651	1	1	41
GO:0030521	androgen receptor signaling pathway	3.91e-02	1.00e+00	4.651	1	1	41
GO:0045727	positive regulation of translation	4.19e-02	1.00e+00	4.549	1	1	44
GO:0008344	adult locomotory behavior	4.19e-02	1.00e+00	4.549	1	1	44
GO:0019003	GDP binding	4.47e-02	1.00e+00	4.454	1	2	47
GO:0006879	cellular iron ion homeostasis	4.84e-02	1.00e+00	4.336	1	1	51
GO:0008284	positive regulation of cell proliferation	5.16e-02	1.00e+00	2.431	2	7	382
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	5.30e-02	1.00e+00	4.201	1	1	56
GO:0005643	nuclear pore	5.40e-02	1.00e+00	4.176	1	1	57
GO:0006417	regulation of translation	5.86e-02	1.00e+00	4.055	1	2	62
GO:0003729	mRNA binding	6.77e-02	1.00e+00	3.839	1	2	72
GO:0000785	chromatin	6.86e-02	1.00e+00	3.819	1	1	73
GO:0005929	cilium	7.22e-02	1.00e+00	3.742	1	1	77
GO:0005179	hormone activity	7.40e-02	1.00e+00	3.705	1	1	79
GO:0042384	cilium assembly	8.04e-02	1.00e+00	3.582	1	1	86
GO:0042470	melanosome	8.48e-02	1.00e+00	3.501	1	2	91
GO:0005794	Golgi apparatus	1.16e-01	1.00e+00	1.756	2	9	610
GO:0008286	insulin receptor signaling pathway	1.29e-01	1.00e+00	2.859	1	3	142
GO:0005737	cytoplasm	1.32e-01	1.00e+00	0.714	6	43	3767
GO:0019904	protein domain specific binding	1.60e-01	1.00e+00	2.525	1	3	179
GO:0003924	GTPase activity	1.75e-01	1.00e+00	2.387	1	7	197
GO:0005765	lysosomal membrane	1.80e-01	1.00e+00	2.343	1	2	203
GO:0006184	GTP catabolic process	1.89e-01	1.00e+00	2.267	1	7	214
GO:0007067	mitotic nuclear division	1.99e-01	1.00e+00	2.182	1	5	227
GO:0003713	transcription coactivator activity	2.07e-01	1.00e+00	2.120	1	4	237
GO:0005730	nucleolus	2.08e-01	1.00e+00	0.913	3	24	1641
GO:0000166	nucleotide binding	2.24e-01	1.00e+00	1.992	1	2	259
GO:0007264	small GTPase mediated signal transduction	2.39e-01	1.00e+00	1.885	1	7	279
GO:0005575	cellular_component	2.39e-01	1.00e+00	1.885	1	1	279
GO:0005525	GTP binding	2.62e-01	1.00e+00	1.733	1	7	310
GO:0007275	multicellular organismal development	2.67e-01	1.00e+00	1.705	1	1	316
GO:0005813	centrosome	2.74e-01	1.00e+00	1.660	1	5	326
GO:0003682	chromatin binding	2.75e-01	1.00e+00	1.656	1	3	327
GO:0005654	nucleoplasm	2.83e-01	1.00e+00	0.929	2	15	1082
GO:0000139	Golgi membrane	2.99e-01	1.00e+00	1.513	1	6	361
GO:0008150	biological_process	3.18e-01	1.00e+00	1.405	1	3	389
GO:0055085	transmembrane transport	3.49e-01	1.00e+00	1.244	1	3	435
GO:0005515	protein binding	3.57e-01	1.00e+00	0.260	7	62	6024
GO:0045893	positive regulation of transcription, DNA-templated	3.76e-01	1.00e+00	1.108	1	5	478
GO:0005783	endoplasmic reticulum	4.23e-01	1.00e+00	0.890	1	3	556
GO:0005634	nucleus	4.69e-01	1.00e+00	0.176	5	43	4559
GO:0007165	signal transduction	5.97e-01	1.00e+00	0.184	1	3	907
GO:0005615	extracellular space	6.18e-01	1.00e+00	0.106	1	2	957
GO:0044281	small molecule metabolic process	7.07e-01	1.00e+00	-0.233	1	15	1211
GO:0003677	DNA binding	7.09e-01	1.00e+00	-0.242	1	3	1218
GO:0005886	plasma membrane	9.37e-01	1.00e+00	-1.326	1	20	2582

Tai-Luciferase

int-snw-5901

Statistics

Genes (14)

Interactions (32)

Related GO terms (108)