reg-snw-6046

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.210	2.57e-07	4.41e-02	3.35e-02

chia-screen-data-Fav-reg-snw-6046 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
HIVEP3	59269	1	-2.877	2.210	7	-	Yes	Yes
[ BRD2 ]	6046	1	-0.915	2.210	9	TF	-	-
CAPRIN1	4076	2	-1.934	2.240	42	-	-	-
ARFIP2	23647	1	-2.020	2.210	1	-	Yes	-
KIR3DL1	3811	2	-2.465	2.238	9	-	Yes	Yes
YY1	7528	2	-2.572	2.238	54	TF	Yes	Yes
C16orf13	84326	12	-2.090	2.492	36	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
SYMPK	8189	11	-1.890	2.492	51	TF	-	-
TRIM28	10155	1	-1.234	2.210	190	TF	-	-
ADA	100	2	-2.499	2.307	8	-	Yes	Yes

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
KIR3DL1	3811	YY1	7528	pd	<	reg.TRANSFAC.txt: no annot
TRIM28	10155	HIVEP3	59269	pd	>	reg.pazar.txt: no annot
TRIM28	10155	ARFIP2	23647	pd	>	reg.ITFP.txt: no annot
ADA	100	YY1	7528	pd	<	reg.pazar.txt: no annot; reg.oreganno.txt: no annot
SYMPK	8189	TRIM28	10155	pd	<>	reg.ITFP.txt: no annot
SYMPK	8189	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
BRD2	6046	YY1	7528	pd	<>	reg.ITFP.txt: no annot
CAPRIN1	4076	TRIM28	10155	pd	<	reg.ITFP.txt: no annot
BRD2	6046	TRIM28	10155	pd	<>	reg.ITFP.txt: no annot
SYMPK	8189	RNF40	9810	pd	<>	reg.ITFP.txt: no annot
BRD2	6046	SYMPK	8189	pd	<>	reg.ITFP.txt: no annot
GPS1	2873	C16orf13	84326	pd	>	reg.ITFP.txt: no annot

Related GO terms (166)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0060407	negative regulation of penile erection	1.33e-03	1.00e+00	9.553	1	1	1
GO:0006157	deoxyadenosine catabolic process	1.33e-03	1.00e+00	9.553	1	1	1
GO:0046111	xanthine biosynthetic process	1.33e-03	1.00e+00	9.553	1	1	1
GO:0032261	purine nucleotide salvage	1.33e-03	1.00e+00	9.553	1	1	1
GO:0060169	negative regulation of adenosine receptor signaling pathway	1.33e-03	1.00e+00	9.553	1	1	1
GO:0070256	negative regulation of mucus secretion	1.33e-03	1.00e+00	9.553	1	1	1
GO:0001883	purine nucleoside binding	1.33e-03	1.00e+00	9.553	1	1	1
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	1.33e-03	1.00e+00	9.553	1	1	1
GO:0034696	response to prostaglandin F	2.66e-03	1.00e+00	8.553	1	1	2
GO:0002314	germinal center B cell differentiation	2.66e-03	1.00e+00	8.553	1	1	2
GO:0035851	Krueppel-associated box domain binding	2.66e-03	1.00e+00	8.553	1	1	2
GO:0006403	RNA localization	2.66e-03	1.00e+00	8.553	1	1	2
GO:0060028	convergent extension involved in axis elongation	2.66e-03	1.00e+00	8.553	1	1	2
GO:0006154	adenosine catabolic process	2.66e-03	1.00e+00	8.553	1	1	2
GO:0030109	HLA-B specific inhibitory MHC class I receptor activity	2.66e-03	1.00e+00	8.553	1	1	2
GO:0046103	inosine biosynthetic process	2.66e-03	1.00e+00	8.553	1	1	2
GO:0060205	cytoplasmic membrane-bounded vesicle lumen	2.66e-03	1.00e+00	8.553	1	1	2
GO:0060669	embryonic placenta morphogenesis	3.99e-03	1.00e+00	7.968	1	1	3
GO:0033632	regulation of cell-cell adhesion mediated by integrin	3.99e-03	1.00e+00	7.968	1	1	3
GO:0046061	dATP catabolic process	3.99e-03	1.00e+00	7.968	1	1	3
GO:0043103	hypoxanthine salvage	3.99e-03	1.00e+00	7.968	1	1	3
GO:0002636	positive regulation of germinal center formation	3.99e-03	1.00e+00	7.968	1	1	3
GO:0002686	negative regulation of leukocyte migration	3.99e-03	1.00e+00	7.968	1	1	3
GO:0050862	positive regulation of T cell receptor signaling pathway	5.32e-03	1.00e+00	7.553	1	1	4
GO:0002906	negative regulation of mature B cell apoptotic process	5.32e-03	1.00e+00	7.553	1	1	4
GO:0033503	HULC complex	5.32e-03	1.00e+00	7.553	1	1	4
GO:0001821	histamine secretion	5.32e-03	1.00e+00	7.553	1	1	4
GO:0070244	negative regulation of thymocyte apoptotic process	6.64e-03	1.00e+00	7.231	1	2	5
GO:0004000	adenosine deaminase activity	6.64e-03	1.00e+00	7.231	1	1	5
GO:0061003	positive regulation of dendritic spine morphogenesis	6.64e-03	1.00e+00	7.231	1	1	5
GO:0033089	positive regulation of T cell differentiation in thymus	6.64e-03	1.00e+00	7.231	1	1	5
GO:0070087	chromo shadow domain binding	7.96e-03	1.00e+00	6.968	1	1	6
GO:0045987	positive regulation of smooth muscle contraction	7.96e-03	1.00e+00	6.968	1	1	6
GO:0005737	cytoplasm	9.21e-03	1.00e+00	1.190	8	127	2633
GO:0010460	positive regulation of heart rate	9.28e-03	1.00e+00	6.746	1	1	7
GO:0048541	Peyer's patch development	9.28e-03	1.00e+00	6.746	1	2	7
GO:0033197	response to vitamin E	9.28e-03	1.00e+00	6.746	1	1	7
GO:0000400	four-way junction DNA binding	9.28e-03	1.00e+00	6.746	1	3	7
GO:0033523	histone H2B ubiquitination	9.28e-03	1.00e+00	6.746	1	1	7
GO:0031011	Ino80 complex	1.06e-02	1.00e+00	6.553	1	3	8
GO:0010388	cullin deneddylation	1.06e-02	1.00e+00	6.553	1	4	8
GO:0042993	positive regulation of transcription factor import into nucleus	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010390	histone monoubiquitination	1.06e-02	1.00e+00	6.553	1	2	8
GO:0046638	positive regulation of alpha-beta T cell differentiation	1.06e-02	1.00e+00	6.553	1	1	8
GO:0043101	purine-containing compound salvage	1.06e-02	1.00e+00	6.553	1	1	8
GO:0010225	response to UV-C	1.19e-02	1.00e+00	6.383	1	2	9
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	1.19e-02	1.00e+00	6.383	1	2	9
GO:0070273	phosphatidylinositol-4-phosphate binding	1.19e-02	1.00e+00	6.383	1	1	9
GO:0048566	embryonic digestive tract development	1.19e-02	1.00e+00	6.383	1	1	9
GO:0008270	zinc ion binding	1.27e-02	1.00e+00	2.047	4	39	727
GO:0005095	GTPase inhibitor activity	1.32e-02	1.00e+00	6.231	1	1	10
GO:0031529	ruffle organization	1.32e-02	1.00e+00	6.231	1	2	10
GO:0035307	positive regulation of protein dephosphorylation	1.32e-02	1.00e+00	6.231	1	1	10
GO:1902187	negative regulation of viral release from host cell	1.32e-02	1.00e+00	6.231	1	1	10
GO:0003714	transcription corepressor activity	1.38e-02	1.00e+00	3.455	2	5	137
GO:0031625	ubiquitin protein ligase binding	1.40e-02	1.00e+00	3.444	2	7	138
GO:0030742	GTP-dependent protein binding	1.46e-02	1.00e+00	6.094	1	1	11
GO:0050775	positive regulation of dendrite morphogenesis	1.46e-02	1.00e+00	6.094	1	1	11
GO:0016874	ligase activity	1.55e-02	1.00e+00	3.363	2	11	146
GO:0051276	chromosome organization	1.59e-02	1.00e+00	5.968	1	2	12
GO:0070577	lysine-acetylated histone binding	1.59e-02	1.00e+00	5.968	1	2	12
GO:0017075	syntaxin-1 binding	1.72e-02	1.00e+00	5.853	1	1	13
GO:0048593	camera-type eye morphogenesis	1.72e-02	1.00e+00	5.853	1	1	13
GO:0032839	dendrite cytoplasm	1.98e-02	1.00e+00	5.646	1	1	15
GO:0000188	inactivation of MAPK activity	1.98e-02	1.00e+00	5.646	1	1	15
GO:0007283	spermatogenesis	2.03e-02	1.00e+00	3.161	2	4	168
GO:0005719	nuclear euchromatin	2.11e-02	1.00e+00	5.553	1	2	16
GO:0050850	positive regulation of calcium-mediated signaling	2.24e-02	1.00e+00	5.466	1	1	17
GO:0001829	trophectodermal cell differentiation	2.24e-02	1.00e+00	5.466	1	2	17
GO:0043278	response to morphine	2.24e-02	1.00e+00	5.466	1	2	17
GO:0004842	ubiquitin-protein transferase activity	2.28e-02	1.00e+00	3.069	2	17	179
GO:0006378	mRNA polyadenylation	2.37e-02	1.00e+00	5.383	1	3	18
GO:0045739	positive regulation of DNA repair	2.37e-02	1.00e+00	5.383	1	3	18
GO:0031519	PcG protein complex	2.37e-02	1.00e+00	5.383	1	3	18
GO:0003713	transcription coactivator activity	2.40e-02	1.00e+00	3.029	2	21	184
GO:0048365	Rac GTPase binding	2.50e-02	1.00e+00	5.305	1	2	19
GO:0030032	lamellipodium assembly	2.63e-02	1.00e+00	5.231	1	2	20
GO:0005720	nuclear heterochromatin	2.63e-02	1.00e+00	5.231	1	3	20
GO:0005525	GTP binding	2.73e-02	1.00e+00	2.931	2	12	197
GO:0016925	protein sumoylation	2.89e-02	1.00e+00	5.094	1	3	22
GO:0006357	regulation of transcription from RNA polymerase II promoter	2.89e-02	1.00e+00	2.888	2	14	203
GO:0006144	purine nucleobase metabolic process	3.15e-02	1.00e+00	4.968	1	2	24
GO:0008180	COP9 signalosome	3.15e-02	1.00e+00	4.968	1	6	24
GO:0001890	placenta development	3.41e-02	1.00e+00	4.853	1	2	26
GO:0010494	cytoplasmic stress granule	3.41e-02	1.00e+00	4.853	1	4	26
GO:0048286	lung alveolus development	3.54e-02	1.00e+00	4.798	1	1	27
GO:0001837	epithelial to mesenchymal transition	3.54e-02	1.00e+00	4.798	1	1	27
GO:0034644	cellular response to UV	3.67e-02	1.00e+00	4.746	1	1	28
GO:0032588	trans-Golgi network membrane	3.79e-02	1.00e+00	4.695	1	1	29
GO:0051259	protein oligomerization	3.79e-02	1.00e+00	4.695	1	3	29
GO:0007155	cell adhesion	4.05e-02	1.00e+00	2.622	2	8	244
GO:0003723	RNA binding	4.14e-02	1.00e+00	2.605	2	22	247
GO:0042110	T cell activation	4.31e-02	1.00e+00	4.509	1	2	33
GO:0030890	positive regulation of B cell proliferation	4.31e-02	1.00e+00	4.509	1	2	33
GO:0017148	negative regulation of translation	4.31e-02	1.00e+00	4.509	1	5	33
GO:0035914	skeletal muscle cell differentiation	4.31e-02	1.00e+00	4.509	1	3	33
GO:0007254	JNK cascade	4.44e-02	1.00e+00	4.466	1	1	34
GO:0042542	response to hydrogen peroxide	4.69e-02	1.00e+00	4.383	1	1	36
GO:0000724	double-strand break repair via homologous recombination	5.45e-02	1.00e+00	4.161	1	5	42
GO:0000932	cytoplasmic mRNA processing body	5.58e-02	1.00e+00	4.127	1	3	43
GO:0000151	ubiquitin ligase complex	6.21e-02	1.00e+00	3.968	1	4	48
GO:0050728	negative regulation of inflammatory response	6.33e-02	1.00e+00	3.938	1	1	49
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	6.46e-02	1.00e+00	3.909	1	2	50
GO:0006334	nucleosome assembly	6.58e-02	1.00e+00	3.881	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	6.58e-02	1.00e+00	3.881	1	2	51
GO:0016020	membrane	6.65e-02	1.00e+00	1.316	4	56	1207
GO:0001726	ruffle	6.83e-02	1.00e+00	3.825	1	2	53
GO:0050776	regulation of immune response	7.08e-02	1.00e+00	3.772	1	2	55
GO:0009952	anterior/posterior pattern specification	7.70e-02	1.00e+00	3.646	1	3	60
GO:0005923	tight junction	8.20e-02	1.00e+00	3.553	1	2	64
GO:0016568	chromatin modification	8.69e-02	1.00e+00	3.466	1	3	68
GO:0045893	positive regulation of transcription, DNA-templated	8.76e-02	1.00e+00	1.995	2	21	377
GO:0006928	cellular component movement	8.93e-02	1.00e+00	3.424	1	6	70
GO:0001889	liver development	9.06e-02	1.00e+00	3.403	1	4	71
GO:0016363	nuclear matrix	9.30e-02	1.00e+00	3.363	1	10	73
GO:0005938	cell cortex	9.79e-02	1.00e+00	3.286	1	6	77
GO:0005634	nucleus	1.02e-01	1.00e+00	0.696	7	158	3246
GO:0030036	actin cytoskeleton organization	1.13e-01	1.00e+00	3.061	1	4	90
GO:0006511	ubiquitin-dependent protein catabolic process	1.16e-01	1.00e+00	3.029	1	6	92
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.21e-01	1.00e+00	1.720	2	29	456
GO:0007568	aging	1.22e-01	1.00e+00	2.953	1	3	97
GO:0003677	DNA binding	1.25e-01	1.00e+00	1.251	3	52	947
GO:0005764	lysosome	1.25e-01	1.00e+00	2.909	1	2	100
GO:0005515	protein binding	1.30e-01	1.00e+00	0.543	8	198	4124
GO:0046777	protein autophosphorylation	1.32e-01	1.00e+00	2.825	1	3	106
GO:0043005	neuron projection	1.41e-01	1.00e+00	2.733	1	6	113
GO:0007049	cell cycle	1.43e-01	1.00e+00	2.707	1	8	115
GO:0001666	response to hypoxia	1.44e-01	1.00e+00	2.695	1	2	116
GO:0006974	cellular response to DNA damage stimulus	1.50e-01	1.00e+00	2.634	1	11	121
GO:0004672	protein kinase activity	1.54e-01	1.00e+00	2.587	1	5	125
GO:0032403	protein complex binding	1.60e-01	1.00e+00	2.531	1	5	130
GO:0019904	protein domain specific binding	1.60e-01	1.00e+00	2.531	1	4	130
GO:0009897	external side of plasma membrane	1.61e-01	1.00e+00	2.520	1	3	131
GO:0006351	transcription, DNA-templated	1.66e-01	1.00e+00	1.066	3	47	1076
GO:0044212	transcription regulatory region DNA binding	1.75e-01	1.00e+00	2.393	1	13	143
GO:0005887	integral component of plasma membrane	1.76e-01	1.00e+00	1.386	2	8	575
GO:0005667	transcription factor complex	1.79e-01	1.00e+00	2.353	1	8	147
GO:0003700	sequence-specific DNA binding transcription factor activity	1.79e-01	1.00e+00	1.368	2	22	582
GO:0006367	transcription initiation from RNA polymerase II promoter	1.94e-01	1.00e+00	2.222	1	18	161
GO:0007165	signal transduction	1.97e-01	1.00e+00	1.282	2	24	618
GO:0030425	dendrite	2.00e-01	1.00e+00	2.178	1	2	166
GO:0005886	plasma membrane	2.01e-01	1.00e+00	0.752	4	46	1784
GO:0043025	neuronal cell body	2.05e-01	1.00e+00	2.135	1	3	171
GO:0007264	small GTPase mediated signal transduction	2.09e-01	1.00e+00	2.110	1	8	174
GO:0016567	protein ubiquitination	2.23e-01	1.00e+00	1.998	1	14	188
GO:0005856	cytoskeleton	2.26e-01	1.00e+00	1.983	1	8	190
GO:0006955	immune response	2.36e-01	1.00e+00	1.909	1	2	200
GO:0006281	DNA repair	2.39e-01	1.00e+00	1.888	1	24	203
GO:0030154	cell differentiation	2.40e-01	1.00e+00	1.881	1	5	204
GO:0030054	cell junction	2.54e-01	1.00e+00	1.785	1	5	218
GO:0042493	response to drug	2.59e-01	1.00e+00	1.759	1	4	222
GO:0003682	chromatin binding	2.88e-01	1.00e+00	1.576	1	15	252
GO:0044822	poly(A) RNA binding	2.88e-01	1.00e+00	0.911	2	45	799
GO:0043565	sequence-specific DNA binding	3.10e-01	1.00e+00	1.450	1	8	275
GO:0009986	cell surface	3.25e-01	1.00e+00	1.368	1	5	291
GO:0005654	nucleoplasm	3.28e-01	1.00e+00	0.778	2	68	876
GO:0045892	negative regulation of transcription, DNA-templated	3.49e-01	1.00e+00	1.245	1	17	317
GO:0042803	protein homodimerization activity	4.42e-01	1.00e+00	0.811	1	13	428
GO:0045087	innate immune response	4.60e-01	1.00e+00	0.733	1	12	452
GO:0010467	gene expression	5.20e-01	1.00e+00	0.490	1	49	535
GO:0005615	extracellular space	5.92e-01	1.00e+00	0.206	1	15	651
GO:0005739	mitochondrion	5.97e-01	1.00e+00	0.189	1	32	659
GO:0044281	small molecule metabolic process	6.91e-01	1.00e+00	-0.168	1	35	844
GO:0005829	cytosol	7.18e-01	1.00e+00	-0.250	2	88	1787
GO:0046872	metal ion binding	7.30e-01	1.00e+00	-0.314	1	24	934
GO:0005730	nucleolus	8.23e-01	1.00e+00	-0.696	1	74	1217

chia-Fav

reg-snw-6046

Statistics

Genes (13)

Interactions (13)

Related GO terms (166)