int-snw-8241

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.129	7.62e-19	9.01e-06	2.01e-04

chia-screen-data-Fav-int-snw-8241 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
WDR82	80335	7	-2.455	3.129	64	Yes	-
[ RBM10 ]	8241	2	-2.329	3.129	40	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
SF3A1	10291	4	-2.787	3.129	43	Yes	Yes

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HCFC1	3054	WDR82	80335	pp	--	int.I2D: BioGrid
RBM10	8241	WDR82	80335	pp	--	int.I2D: BioGrid
RBM10	8241	SF3A1	10291	pp	--	int.Mint: MI:0915(physical association)

Related GO terms (83)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0048188	Set1C/COMPASS complex	3.46e-06	4.99e-02	9.324	2	4	9
GO:0060795	cell fate commitment involved in formation of primary germ layer	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	3.47e-04	1.00e+00	11.494	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	3.47e-04	1.00e+00	11.494	1	1	1
GO:0019046	release from viral latency	6.93e-04	1.00e+00	10.494	1	2	2
GO:0009786	regulation of asymmetric cell division	6.93e-04	1.00e+00	10.494	1	1	2
GO:0005684	U2-type spliceosomal complex	6.93e-04	1.00e+00	10.494	1	1	2
GO:0060913	cardiac cell fate determination	1.04e-03	1.00e+00	9.909	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.04e-03	1.00e+00	9.909	1	1	3
GO:0006397	mRNA processing	1.20e-03	1.00e+00	5.172	2	10	160
GO:0070461	SAGA-type complex	1.73e-03	1.00e+00	9.172	1	2	5
GO:0001714	endodermal cell fate specification	1.73e-03	1.00e+00	9.172	1	1	5
GO:0000389	mRNA 3'-splice site recognition	1.73e-03	1.00e+00	9.172	1	2	5
GO:0034393	positive regulation of smooth muscle cell apoptotic process	1.73e-03	1.00e+00	9.172	1	2	5
GO:0008380	RNA splicing	2.41e-03	1.00e+00	4.661	2	22	228
GO:0072357	PTW/PP1 phosphatase complex	2.42e-03	1.00e+00	8.687	1	2	7
GO:0070688	MLL5-L complex	2.77e-03	1.00e+00	8.494	1	1	8
GO:0043254	regulation of protein complex assembly	2.77e-03	1.00e+00	8.494	1	1	8
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	3.12e-03	1.00e+00	8.324	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	3.12e-03	1.00e+00	8.324	1	5	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	3.12e-03	1.00e+00	8.324	1	5	9
GO:0035413	positive regulation of catenin import into nucleus	3.46e-03	1.00e+00	8.172	1	2	10
GO:0044822	poly(A) RNA binding	3.50e-03	1.00e+00	3.035	3	50	1056
GO:0005654	nucleoplasm	3.75e-03	1.00e+00	3.000	3	64	1082
GO:0060391	positive regulation of SMAD protein import into nucleus	3.81e-03	1.00e+00	8.035	1	4	11
GO:0035198	miRNA binding	4.15e-03	1.00e+00	7.909	1	1	12
GO:0070935	3'-UTR-mediated mRNA stabilization	4.15e-03	1.00e+00	7.909	1	3	12
GO:0042800	histone methyltransferase activity (H3-K4 specific)	4.50e-03	1.00e+00	7.794	1	3	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	4.50e-03	1.00e+00	7.794	1	2	13
GO:0003682	chromatin binding	4.90e-03	1.00e+00	4.141	2	19	327
GO:0043981	histone H4-K5 acetylation	5.19e-03	1.00e+00	7.587	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	5.19e-03	1.00e+00	7.587	1	3	15
GO:0001824	blastocyst development	5.19e-03	1.00e+00	7.587	1	2	15
GO:0043982	histone H4-K8 acetylation	5.19e-03	1.00e+00	7.587	1	5	15
GO:0051568	histone H3-K4 methylation	5.88e-03	1.00e+00	7.407	1	3	17
GO:0043984	histone H4-K16 acetylation	6.57e-03	1.00e+00	7.246	1	5	19
GO:0000123	histone acetyltransferase complex	7.26e-03	1.00e+00	7.102	1	6	21
GO:0035097	histone methyltransferase complex	7.26e-03	1.00e+00	7.102	1	3	21
GO:0045787	positive regulation of cell cycle	7.60e-03	1.00e+00	7.035	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	7.60e-03	1.00e+00	7.035	1	4	22
GO:0006366	transcription from RNA polymerase II promoter	7.94e-03	1.00e+00	3.783	2	30	419
GO:0071339	MLL1 complex	9.33e-03	1.00e+00	6.739	1	6	27
GO:0042802	identical protein binding	1.05e-02	1.00e+00	3.575	2	19	484
GO:0005730	nucleolus	1.23e-02	1.00e+00	2.399	3	66	1641
GO:0005515	protein binding	1.27e-02	1.00e+00	1.260	5	198	6024
GO:0035019	somatic stem cell maintenance	1.38e-02	1.00e+00	6.172	1	6	40
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.44e-02	1.00e+00	3.339	2	37	570
GO:0009611	response to wounding	1.79e-02	1.00e+00	5.794	1	5	52
GO:0003700	sequence-specific DNA binding transcription factor activity	2.13e-02	1.00e+00	3.045	2	39	699
GO:0010468	regulation of gene expression	2.34e-02	1.00e+00	5.407	1	2	68
GO:0000785	chromatin	2.51e-02	1.00e+00	5.304	1	6	73
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	2.54e-02	1.00e+00	5.285	1	4	74
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.68e-02	1.00e+00	2.870	2	41	789
GO:0071013	catalytic step 2 spliceosome	2.68e-02	1.00e+00	5.209	1	7	78
GO:0005681	spliceosomal complex	2.84e-02	1.00e+00	5.119	1	3	83
GO:0009653	anatomical structure morphogenesis	2.84e-02	1.00e+00	5.119	1	2	83
GO:0050821	protein stabilization	3.01e-02	1.00e+00	5.035	1	3	88
GO:0005634	nucleus	3.73e-02	1.00e+00	1.340	4	159	4559
GO:0006325	chromatin organization	4.02e-02	1.00e+00	4.612	1	12	118
GO:0006355	regulation of transcription, DNA-templated	4.15e-02	1.00e+00	2.533	2	43	997
GO:0010628	positive regulation of gene expression	4.96e-02	1.00e+00	4.304	1	7	146
GO:0000398	mRNA splicing, via spliceosome	5.56e-02	1.00e+00	4.137	1	15	164
GO:0044212	transcription regulatory region DNA binding	5.69e-02	1.00e+00	4.102	1	17	168
GO:0007049	cell cycle	5.89e-02	1.00e+00	4.051	1	6	174
GO:0005667	transcription factor complex	5.92e-02	1.00e+00	4.043	1	17	175
GO:0031625	ubiquitin protein ligase binding	6.02e-02	1.00e+00	4.018	1	5	178
GO:0032403	protein complex binding	6.19e-02	1.00e+00	3.978	1	6	183
GO:0003713	transcription coactivator activity	7.95e-02	1.00e+00	3.605	1	24	237
GO:0008134	transcription factor binding	8.11e-02	1.00e+00	3.575	1	18	242
GO:0043025	neuronal cell body	8.21e-02	1.00e+00	3.558	1	9	245
GO:0000166	nucleotide binding	8.66e-02	1.00e+00	3.477	1	13	259
GO:0003723	RNA binding	1.13e-01	1.00e+00	3.076	1	18	342
GO:0043565	sequence-specific DNA binding	1.14e-01	1.00e+00	3.060	1	11	346
GO:0008285	negative regulation of cell proliferation	1.17e-01	1.00e+00	3.031	1	10	353
GO:0008150	biological_process	1.28e-01	1.00e+00	2.891	1	4	389
GO:0010467	gene expression	2.11e-01	1.00e+00	2.108	1	45	669
GO:0005739	mitochondrion	3.01e-01	1.00e+00	1.531	1	23	998
GO:0008270	zinc ion binding	3.01e-01	1.00e+00	1.533	1	27	997
GO:0003677	DNA binding	3.57e-01	1.00e+00	1.244	1	49	1218
GO:0005737	cytoplasm	3.91e-01	1.00e+00	0.615	2	124	3767
GO:0016020	membrane	4.62e-01	1.00e+00	0.779	1	46	1681
GO:0005829	cytosol	6.13e-01	1.00e+00	0.209	1	86	2496

chia-Fav

int-snw-8241

Statistics

Genes (5)

Interactions (4)

Related GO terms (83)