int-snw-7621

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.905 2.85e-16 2.03e-04 1.83e-03
chia-screen-data-Fav-int-snw-7621 subnetwork

Genes (5)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Chia-Hits Primary Chia-Hits Secondary
ZFP64 55734 3-3.1742.90814YesYes
NFRKB 4798 48-3.1293.10823YesYes
POU5F1 5460 133-5.1483.538179YesYes
ZNF513 130557 2-2.2562.9057Yes-
[ ZNF70 ] 7621 1-0.8212.9051--

Interactions (4)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
NFRKB 4798 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
ZNF70 7621 ZFP64 55734 pp -- int.I2D: BioGrid;
int.Ravasi: -
ZFP64 55734 ZNF513 130557 pp -- int.I2D: BioGrid;
int.Ravasi: -
POU5F1 5460 ZNF513 130557 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse

Related GO terms (45)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006355regulation of transcription, DNA-templated1.56e-062.26e-023.855543997
GO:0003677DNA binding4.26e-066.15e-023.5665491218
GO:0060795cell fate commitment involved in formation of primary germ layer3.47e-041.00e+0011.494111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway3.47e-041.00e+0011.494111
GO:0060965negative regulation of gene silencing by miRNA3.47e-041.00e+0011.494111
GO:0090308regulation of methylation-dependent chromatin silencing3.47e-041.00e+0011.494111
GO:0009786regulation of asymmetric cell division6.93e-041.00e+0010.494112
GO:0060913cardiac cell fate determination1.04e-031.00e+009.909113
GO:0003130BMP signaling pathway involved in heart induction1.04e-031.00e+009.909113
GO:0044212transcription regulatory region DNA binding1.32e-031.00e+005.102217168
GO:0001714endodermal cell fate specification1.73e-031.00e+009.172115
GO:0005634nucleus3.15e-031.00e+001.66251594559
GO:0035413positive regulation of catenin import into nucleus3.46e-031.00e+008.1721210
GO:0060391positive regulation of SMAD protein import into nucleus3.81e-031.00e+008.0351411
GO:0035198miRNA binding4.15e-031.00e+007.9091112
GO:0042789mRNA transcription from RNA polymerase II promoter4.50e-031.00e+007.7941213
GO:0031011Ino80 complex4.84e-031.00e+007.6871614
GO:0001824blastocyst development5.19e-031.00e+007.5871215
GO:0046872metal ion binding6.46e-031.00e+002.7273291307
GO:0006366transcription from RNA polymerase II promoter7.94e-031.00e+003.783230419
GO:0006351transcription, DNA-templated8.61e-031.00e+002.5813571446
GO:0035019somatic stem cell maintenance1.38e-021.00e+006.1721640
GO:0050896response to stimulus1.38e-021.00e+006.1721240
GO:0060041retina development in camera-type eye1.76e-021.00e+005.8221251
GO:0009611response to wounding1.79e-021.00e+005.7941552
GO:0006310DNA recombination2.23e-021.00e+005.4721765
GO:0010468regulation of gene expression2.34e-021.00e+005.4071268
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity2.54e-021.00e+005.2851474
GO:0002020protease binding2.54e-021.00e+005.2851674
GO:0009653anatomical structure morphogenesis2.84e-021.00e+005.1191283
GO:0007601visual perception5.33e-021.00e+004.20015157
GO:0005667transcription factor complex5.92e-021.00e+004.043117175
GO:0031625ubiquitin protein ligase binding6.02e-021.00e+004.01815178
GO:0008134transcription factor binding8.11e-021.00e+003.575118242
GO:0006281DNA repair8.73e-021.00e+003.466114261
GO:0006954inflammatory response9.24e-021.00e+003.38016277
GO:0043565sequence-specific DNA binding1.14e-011.00e+003.060111346
GO:0003700sequence-specific DNA binding transcription factor activity2.20e-011.00e+002.045139699
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.45e-011.00e+001.870141789
GO:0044822poly(A) RNA binding3.16e-011.00e+001.4501501056
GO:0005654nucleoplasm3.23e-011.00e+001.4151641082
GO:0005730nucleolus4.53e-011.00e+000.8141661641
GO:0005829cytosol6.13e-011.00e+000.2091862496
GO:0005515protein binding6.93e-011.00e+00-0.06221986024
GO:0005737cytoplasm7.80e-011.00e+00-0.38511243767