meta-reg-snw-9055

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-811 wolf-screen-ratio-mammosphere-adherent 0.932 2.10e-15 2.63e-03 4.19e-02 24 22
reg-snw-9055 wolf-screen-ratio-mammosphere-adherent 0.830 8.78e-07 2.82e-03 5.39e-03 9 7
int-snw-3305 wolf-screen-ratio-mammosphere-adherent 0.942 8.57e-16 2.11e-03 3.57e-02 23 22
wolf-screen-ratio-mammosphere-adherent-meta-reg-snw-9055 subnetwork

Genes (35)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
ATP6V1B2 526 530.8811.076278--
CAD 790 910.8070.973400--
CALR 811 38-0.4180.93279-Yes
CCNA2 890 540.5500.973246Yes-
PSMD1 5707 860.8360.830118Yes-
EEF2 1938 640.8901.043301Yes-
MCM5 4174 230.5780.830273Yes-
RPS11 6205 620.9931.113175Yes-
EFTUD2 9343 930.8830.956108Yes-
PRC1 9055 3-0.3360.83055--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
HSPD1 3329 700.9131.035325Yes-
TACC3 10460 80.8060.83035Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
OGDH 4967 720.8470.802126Yes-
RPSA 3921 1201.3271.151152Yes-
PGD 5226 891.2011.106152Yes-
HSPA1L 3305 34-0.4140.942125-Yes
ACO2 50 651.0001.076191Yes-
PSMD13 5719 560.8480.801114Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
CLTC 1213 560.8841.138247Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
ITGAV 3685 390.5560.94937--
RUVBL2 10856 950.6930.956532Yes-
PSMD6 9861 790.8480.878143Yes-
PSMC1 5700 510.8401.018137Yes-

Interactions (155)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
RPS11 6205 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
CAD 790 MCM5 4174 pd < reg.ITFP.txt: no annot
CAD 790 MCM5 4174 pp -- int.I2D: IntAct_Yeast
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD13 5719 pp -- int.I2D: YeastLow
ACO2 50 OGDH 4967 pp -- int.I2D: YeastLow
RUVBL1 8607 PRC1 9055 pd > reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMD1 5707 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
PSMC1 5700 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
PGD 5226 RAN 5901 pp -- int.I2D: YeastLow
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
ATP6V1B2 526 OGDH 4967 pp -- int.I2D: IntAct_Yeast
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA3 5684 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
MCM5 4174 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
OGDH 4967 RUVBL1 8607 pp -- int.I2D: YeastLow
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, YeastMedium
CALR 811 PSMA3 5684 pp -- int.I2D: BioGrid
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
CALR 811 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
CLTC 1213 RUVBL1 8607 pp -- int.I2D: MINT_Worm, IntAct_Worm
ACTB 60 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ATP6V1B2 526 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
HSPA1L 3305 RUVBL1 8607 pp -- int.I2D: BioGrid
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMD6 9861 RUVBL2 10856 pp -- int.I2D: YeastLow
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
MCM5 4174 PRC1 9055 pd > reg.ITFP.txt: no annot
OGDH 4967 PSMD13 5719 pp -- int.I2D: YeastLow
OGDH 4967 PSMD6 9861 pp -- int.I2D: YeastLow
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
EEF2 1938 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMC1 5700 PSMD1 5707 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, Krogan_Core, MINT_Yeast
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
MCM5 4174 TACC3 10460 pd > reg.ITFP.txt: no annot
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
ACO2 50 PSMC1 5700 pp -- int.I2D: YeastLow
PSMC1 5700 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD13 5719 RUVBL2 10856 pp -- int.I2D: YeastHigh
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, BioGrid, IntAct_Yeast, Krogan_Core, YeastHigh
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
ATP6V1B2 526 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMC1 5700 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
MCM5 4174 PSMD13 5719 pp -- int.I2D: YeastLow
OGDH 4967 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
RUVBL1 8607 PSMD6 9861 pp -- int.I2D: YeastLow
ACO2 50 PGD 5226 pp -- int.I2D: YeastLow
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
CALR 811 ITGAV 3685 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro, in vivo
PSMB7 5695 PSMD13 5719 pd < reg.ITFP.txt: no annot
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
ACO2 50 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HSPA1L 3305 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
HSPA1L 3305 RUVBL2 10856 pp -- int.I2D: BioGrid
CCNA2 890 PRC1 9055 pd > reg.ITFP.txt: no annot
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 RAN 5901 pp -- int.I2D: YeastLow
HSPD1 3329 OGDH 4967 pp -- int.I2D: YeastLow
EEF2 1938 PSMD13 5719 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
OGDH 4967 PSMC1 5700 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMA1 5682 PSMC1 5700 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct
PSMD11 5717 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG
PSMD3 5709 PSMD13 5719 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
PSMD13 5719 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
PSMC1 5700 RUVBL1 8607 pp -- int.I2D: YeastLow
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 MCM5 4174 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2 526 MCM5 4174 pp -- int.I2D: IntAct_Yeast
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (480)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.27e-222.07e-186.376132373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.69e-224.38e-186.299132377
GO:0002474antigen processing and presentation of peptide antigen via MHC class I4.31e-217.04e-176.011132394
GO:0006521regulation of cellular amino acid metabolic process2.71e-204.42e-166.681112150
GO:0000502proteasome complex1.63e-192.66e-156.467112258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.35e-191.04e-146.302112465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest6.35e-191.04e-146.302112265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.53e-182.49e-146.195112470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.93e-184.78e-146.115112474
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process6.29e-181.03e-136.021112579
GO:0000082G1/S transition of mitotic cell cycle1.62e-162.64e-125.2211233150
GO:0042981regulation of apoptotic process1.75e-162.86e-125.2121226151
GO:0016071mRNA metabolic process4.61e-167.53e-124.7651334223
GO:0000209protein polyubiquitination5.21e-168.50e-125.4671121116
GO:0034641cellular nitrogen compound metabolic process1.22e-151.99e-114.9831225177
GO:0016070RNA metabolic process1.75e-152.86e-114.6171334247
GO:0010467gene expression4.85e-157.92e-113.5671758669
GO:0000278mitotic cell cycle3.05e-144.98e-104.0361452398
GO:0005654nucleoplasm6.34e-141.03e-093.01619831095
GO:0016032viral process9.08e-141.48e-093.6951555540
GO:0070062extracellular vesicular exosome1.70e-132.77e-092.21225982516
GO:0005829cytosol2.59e-134.22e-092.186251252562
GO:0022624proteasome accessory complex7.53e-131.23e-087.3636917
GO:0016020membrane1.94e-123.16e-082.48821801746
GO:0005838proteasome regulatory particle2.64e-114.30e-077.6025712
GO:0043066negative regulation of apoptotic process5.02e-118.19e-073.6921230433
GO:0005839proteasome core complex2.83e-104.61e-067.01751118
GO:0004298threonine-type endopeptidase activity5.10e-108.32e-066.86551120
GO:0044281small molecule metabolic process2.15e-093.51e-052.52616571295
GO:0006915apoptotic process1.70e-082.77e-043.1671134571
GO:0019773proteasome core complex, alpha-subunit complex5.02e-078.20e-037.450358
GO:0035267NuA4 histone acetyltransferase complex3.24e-065.28e-026.6433414
GO:0003678DNA helicase activity8.55e-061.40e-016.2023319
GO:0005634nucleus1.04e-051.69e-011.152231314828
GO:0005515protein binding1.07e-051.75e-010.985261726127
GO:0016887ATPase activity1.31e-052.13e-014.01757144
GO:0005844polysome2.01e-053.28e-015.8063425
GO:0051082unfolded protein binding4.91e-058.02e-014.2954695
GO:0044822poly(A) RNA binding6.07e-059.91e-012.11310501078
GO:0032508DNA duplex unwinding9.79e-051.00e+005.0583442
GO:0030529ribonucleoprotein complex1.00e-041.00e+004.03248114
GO:0000812Swr1 complex1.24e-041.00e+006.865238
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding2.08e-041.00e+004.6953554
GO:0051087chaperone binding2.70e-041.00e+004.5673659
GO:0043968histone H2A acetylation2.91e-041.00e+006.2802312
GO:0030234enzyme regulator activity3.43e-041.00e+006.1652313
GO:0031011Ino80 complex4.00e-041.00e+006.0582314
GO:0043234protein complex4.19e-041.00e+002.958517300
GO:0042026protein refolding4.61e-041.00e+005.9582215
GO:0042176regulation of protein catabolic process5.26e-041.00e+005.8652316
GO:0005730nucleolus5.46e-041.00e+001.60711701684
GO:0019901protein kinase binding5.62e-041.00e+002.865521320
GO:0003924GTPase activity8.99e-041.00e+003.20049203
GO:0016363nuclear matrix9.96e-041.00e+003.92731192
GO:0042470melanosome9.96e-041.00e+003.92731092
GO:0033574response to testosterone1.00e-031.00e+005.4062222
GO:0006414translational elongation1.03e-031.00e+003.91131193
GO:0005925focal adhesion1.08e-031.00e+002.656518370
GO:0001649osteoblast differentiation1.09e-031.00e+003.8803695
GO:0043044ATP-dependent chromatin remodeling1.10e-031.00e+005.3422423
GO:0006184GTP catabolic process1.21e-031.00e+003.08449220
GO:0006611protein export from nucleus1.30e-031.00e+005.2212425
GO:0007067mitotic nuclear division1.45e-031.00e+003.013413231
GO:0005759mitochondrial matrix1.50e-031.00e+003.001412233
GO:0071339MLL1 complex1.52e-031.00e+005.1102327
GO:0043967histone H4 acetylation1.63e-031.00e+005.0582328
GO:0031492nucleosomal DNA binding1.63e-031.00e+005.0582428
GO:0006099tricarboxylic acid cycle1.75e-031.00e+005.0072329
GO:0005524ATP binding1.77e-031.00e+001.6329461354
GO:0019058viral life cycle1.89e-031.00e+003.605310115
GO:0033572transferrin transport2.13e-031.00e+004.8652632
GO:0002842positive regulation of T cell mediated immune response to tumor cell2.14e-031.00e+008.865111
GO:0002502peptide antigen assembly with MHC class I protein complex2.14e-031.00e+008.865111
GO:0035867alphav-beta3 integrin-IGF-1-IGF1R complex2.14e-031.00e+008.865111
GO:0048291isotype switching to IgG isotypes2.14e-031.00e+008.865111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.14e-031.00e+008.865111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity2.14e-031.00e+008.865111
GO:0070335aspartate binding2.14e-031.00e+008.865111
GO:0052066entry of symbiont into host cell by promotion of host phagocytosis2.14e-031.00e+008.865111
GO:2000425regulation of apoptotic cell clearance2.14e-031.00e+008.865111
GO:0004151dihydroorotase activity2.14e-031.00e+008.865111
GO:0019521D-gluconate metabolic process2.14e-031.00e+008.865111
GO:0004070aspartate carbamoyltransferase activity2.14e-031.00e+008.865111
GO:2000536negative regulation of entry of bacterium into host cell2.14e-031.00e+008.865111
GO:0002368B cell cytokine production2.14e-031.00e+008.865111
GO:0006325chromatin organization2.29e-031.00e+003.50834123
GO:0050681androgen receptor binding2.99e-031.00e+004.6172438
GO:0022627cytosolic small ribosomal subunit3.15e-031.00e+004.5802339
GO:0044267cellular protein metabolic process3.85e-031.00e+002.236524495
GO:0006200ATP catabolic process3.87e-031.00e+002.622414303
GO:0006457protein folding3.94e-031.00e+003.23138149
GO:0034683integrin alphav-beta3 complex4.28e-031.00e+007.865112
GO:0045252oxoglutarate dehydrogenase complex4.28e-031.00e+007.865122
GO:00515383 iron, 4 sulfur cluster binding4.28e-031.00e+007.865112
GO:0034686integrin alphav-beta8 complex4.28e-031.00e+007.865112
GO:0003994aconitate hydratase activity4.28e-031.00e+007.865112
GO:0006407rRNA export from nucleus4.28e-031.00e+007.865112
GO:0042824MHC class I peptide loading complex4.28e-031.00e+007.865112
GO:0000022mitotic spindle elongation4.28e-031.00e+007.865112
GO:0001846opsonin binding4.28e-031.00e+007.865112
GO:1990430extracellular matrix protein binding4.28e-031.00e+007.865112
GO:0061034olfactory bulb mitral cell layer development4.28e-031.00e+007.865112
GO:0033144negative regulation of intracellular steroid hormone receptor signaling pathway4.28e-031.00e+007.865112
GO:0050748negative regulation of lipoprotein metabolic process4.28e-031.00e+007.865112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.28e-031.00e+007.865112
GO:0019322pentose biosynthetic process4.28e-031.00e+007.865112
GO:0005055laminin receptor activity4.28e-031.00e+007.865112
GO:0034684integrin alphav-beta5 complex4.28e-031.00e+007.865112
GO:0007127meiosis I4.28e-031.00e+007.865112
GO:0070409carbamoyl phosphate biosynthetic process4.28e-031.00e+007.865112
GO:0031100organ regeneration5.13e-031.00e+004.2212450
GO:0005525GTP binding5.13e-031.00e+002.508411328
GO:0006091generation of precursor metabolites and energy5.33e-031.00e+004.1932351
GO:0006986response to unfolded protein5.33e-031.00e+004.1932251
GO:0040008regulation of growth5.33e-031.00e+004.1932351
GO:0003725double-stranded RNA binding5.96e-031.00e+004.1102654
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity6.42e-031.00e+007.280113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb6.42e-031.00e+007.280113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity6.42e-031.00e+007.280113
GO:0045715negative regulation of low-density lipoprotein particle receptor biosynthetic process6.42e-031.00e+007.280113
GO:0071899negative regulation of estrogen receptor binding6.42e-031.00e+007.280113
GO:1900126negative regulation of hyaluronan biosynthetic process6.42e-031.00e+007.280113
GO:0006458'de novo' protein folding6.42e-031.00e+007.280113
GO:0071733transcriptional activation by promoter-enhancer looping6.42e-031.00e+007.280113
GO:0000056ribosomal small subunit export from nucleus6.42e-031.00e+007.280113
GO:0009051pentose-phosphate shunt, oxidative branch6.42e-031.00e+007.280113
GO:0030135coated vesicle6.42e-031.00e+007.280113
GO:0030953astral microtubule organization6.42e-031.00e+007.280113
GO:0044205'de novo' UMP biosynthetic process6.42e-031.00e+007.280113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process6.42e-031.00e+007.280113
GO:0071439clathrin complex6.42e-031.00e+007.280113
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.55e-031.00e+006.865114
GO:0000212meiotic spindle organization8.55e-031.00e+006.865114
GO:003068690S preribosome8.55e-031.00e+006.865114
GO:0032051clathrin light chain binding8.55e-031.00e+006.865114
GO:0043141ATP-dependent 5'-3' DNA helicase activity8.55e-031.00e+006.865114
GO:0006104succinyl-CoA metabolic process8.55e-031.00e+006.865114
GO:0006543glutamine catabolic process8.55e-031.00e+006.865114
GO:0000055ribosomal large subunit export from nucleus8.55e-031.00e+006.865114
GO:0032369negative regulation of lipid transport8.55e-031.00e+006.865114
GO:0051208sequestering of calcium ion8.55e-031.00e+006.865114
GO:1903077negative regulation of protein localization to plasma membrane8.55e-031.00e+006.865114
GO:2000510positive regulation of dendritic cell chemotaxis8.55e-031.00e+006.865114
GO:0006310DNA recombination9.05e-031.00e+003.7992467
GO:0051414response to cortisol1.07e-021.00e+006.543115
GO:0001940male pronucleus1.07e-021.00e+006.543115
GO:0038027apolipoprotein A-I-mediated signaling pathway1.07e-021.00e+006.543115
GO:0071169establishment of protein localization to chromatin1.07e-021.00e+006.543115
GO:0043248proteasome assembly1.07e-021.00e+006.543115
GO:0046696lipopolysaccharide receptor complex1.07e-021.00e+006.543115
GO:0032355response to estradiol1.07e-021.00e+003.6752573
GO:0006102isocitrate metabolic process1.07e-021.00e+006.543115
GO:0005827polar microtubule1.07e-021.00e+006.543115
GO:0006734NADH metabolic process1.07e-021.00e+006.543115
GO:0030976thiamine pyrophosphate binding1.07e-021.00e+006.543115
GO:0005737cytoplasm1.23e-021.00e+000.81515983976
GO:0071013catalytic step 2 spliceosome1.24e-021.00e+003.5612779
GO:0003688DNA replication origin binding1.28e-021.00e+006.280116
GO:0030130clathrin coat of trans-Golgi network vesicle1.28e-021.00e+006.280116
GO:0006101citrate metabolic process1.28e-021.00e+006.280116
GO:0021860pyramidal neuron development1.28e-021.00e+006.280116
GO:0030118clathrin coat1.28e-021.00e+006.280116
GO:0021695cerebellar cortex development1.28e-021.00e+006.280116
GO:0030957Tat protein binding1.28e-021.00e+006.280146
GO:0046134pyrimidine nucleoside biosynthetic process1.28e-021.00e+006.280116
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex1.28e-021.00e+006.280116
GO:0050764regulation of phagocytosis1.28e-021.00e+006.280116
GO:0040020regulation of meiosis1.28e-021.00e+006.280116
GO:0019083viral transcription1.30e-021.00e+003.5252881
GO:0005681spliceosomal complex1.36e-021.00e+003.4902383
GO:0006412translation1.37e-021.00e+002.574315235
GO:0042921glucocorticoid receptor signaling pathway1.49e-021.00e+006.058117
GO:0001849complement component C1q binding1.49e-021.00e+006.058117
GO:0000028ribosomal small subunit assembly1.49e-021.00e+006.058117
GO:0001939female pronucleus1.49e-021.00e+006.058117
GO:0010888negative regulation of lipid storage1.49e-021.00e+006.058127
GO:0033180proton-transporting V-type ATPase, V1 domain1.49e-021.00e+006.058127
GO:0030132clathrin coat of coated pit1.49e-021.00e+006.058117
GO:0006415translational termination1.49e-021.00e+003.4222887
GO:0000930gamma-tubulin complex1.49e-021.00e+006.058117
GO:0031994insulin-like growth factor I binding1.49e-021.00e+006.058117
GO:0050821protein stabilization1.62e-021.00e+003.3572291
GO:0005200structural constituent of cytoskeleton1.69e-021.00e+003.3262793
GO:0033018sarcoplasmic reticulum lumen1.70e-021.00e+005.865118
GO:0070688MLL5-L complex1.70e-021.00e+005.865118
GO:0006554lysine catabolic process1.70e-021.00e+005.865128
GO:0044183protein binding involved in protein folding1.91e-021.00e+005.695119
GO:0033690positive regulation of osteoblast proliferation1.91e-021.00e+005.695119
GO:0014075response to amine1.91e-021.00e+005.695119
GO:0042555MCM complex1.91e-021.00e+005.695129
GO:0008494translation activator activity1.91e-021.00e+005.695119
GO:0006228UTP biosynthetic process1.91e-021.00e+005.695119
GO:0010389regulation of G2/M transition of mitotic cell cycle1.91e-021.00e+005.695119
GO:0031000response to caffeine1.91e-021.00e+005.695129
GO:0022417protein maturation by protein folding1.91e-021.00e+005.695119
GO:0022027interkinetic nuclear migration1.91e-021.00e+005.695119
GO:0042802identical protein binding2.03e-021.00e+001.926418491
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.09e-021.00e+003.16528104
GO:0002199zona pellucida receptor complex2.12e-021.00e+005.5431110
GO:0043032positive regulation of macrophage activation2.12e-021.00e+005.5431110
GO:0051604protein maturation2.12e-021.00e+005.5431110
GO:0021756striatum development2.12e-021.00e+005.5431110
GO:0006098pentose-phosphate shunt2.33e-021.00e+005.4061311
GO:0032727positive regulation of interferon-alpha production2.33e-021.00e+005.4061111
GO:0048387negative regulation of retinoic acid receptor signaling pathway2.33e-021.00e+005.4061111
GO:0045120pronucleus2.33e-021.00e+005.4061111
GO:0033762response to glucagon2.33e-021.00e+005.4061111
GO:0015630microtubule cytoskeleton2.40e-021.00e+003.05825112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.48e-021.00e+003.032210114
GO:0005819spindle2.48e-021.00e+003.03227114
GO:0032886regulation of microtubule-based process2.54e-021.00e+005.2801412
GO:00709353'-UTR-mediated mRNA stabilization2.54e-021.00e+005.2801212
GO:0021794thalamus development2.54e-021.00e+005.2801112
GO:0072562blood microparticle2.56e-021.00e+003.00724116
GO:0044237cellular metabolic process2.64e-021.00e+002.98323118
GO:0042994cytoplasmic sequestering of transcription factor2.75e-021.00e+005.1651113
GO:0010745negative regulation of macrophage derived foam cell differentiation2.75e-021.00e+005.1651213
GO:0001530lipopolysaccharide binding2.75e-021.00e+005.1651213
GO:0008266poly(U) RNA binding2.75e-021.00e+005.1651113
GO:0051131chaperone-mediated protein complex assembly2.75e-021.00e+005.1651113
GO:0043277apoptotic cell clearance2.96e-021.00e+005.0581114
GO:0007020microtubule nucleation2.96e-021.00e+005.0581114
GO:0007095mitotic G2 DNA damage checkpoint2.96e-021.00e+005.0581114
GO:0071285cellular response to lithium ion2.96e-021.00e+005.0581214
GO:0005506iron ion binding3.02e-021.00e+002.87623127
GO:0035066positive regulation of histone acetylation3.17e-021.00e+004.9581115
GO:0050431transforming growth factor beta binding3.17e-021.00e+004.9581115
GO:0046961proton-transporting ATPase activity, rotational mechanism3.17e-021.00e+004.9581315
GO:0006413translational initiation3.20e-021.00e+002.832212131
GO:0009615response to virus3.25e-021.00e+002.82126132
GO:0000790nuclear chromatin3.29e-021.00e+002.81027133
GO:0042562hormone binding3.38e-021.00e+004.8651116
GO:0046034ATP metabolic process3.38e-021.00e+004.8651116
GO:0071682endocytic vesicle lumen3.38e-021.00e+004.8651116
GO:0050998nitric-oxide synthase binding3.38e-021.00e+004.8651116
GO:00061032-oxoglutarate metabolic process3.38e-021.00e+004.8651116
GO:0031589cell-substrate adhesion3.38e-021.00e+004.8651116
GO:0000086G2/M transition of mitotic cell cycle3.47e-021.00e+002.76727137
GO:0005813centrosome3.56e-021.00e+002.045312339
GO:0031527filopodium membrane3.59e-021.00e+004.7781117
GO:0010243response to organonitrogen compound3.59e-021.00e+004.7781217
GO:0050919negative chemotaxis3.59e-021.00e+004.7781117
GO:0003746translation elongation factor activity3.59e-021.00e+004.7781317
GO:0031528microvillus membrane3.59e-021.00e+004.7781117
GO:0031258lamellipodium membrane3.59e-021.00e+004.7781217
GO:0075733intracellular transport of virus3.59e-021.00e+004.7781217
GO:0050870positive regulation of T cell activation3.59e-021.00e+004.7781117
GO:0003735structural constituent of ribosome3.66e-021.00e+002.72628141
GO:0046718viral entry into host cell3.79e-021.00e+004.6951118
GO:0017025TBP-class protein binding3.79e-021.00e+004.6951218
GO:0071392cellular response to estradiol stimulus3.79e-021.00e+004.6951118
GO:0006541glutamine metabolic process3.79e-021.00e+004.6951118
GO:0031122cytoplasmic microtubule organization3.79e-021.00e+004.6951218
GO:0070371ERK1 and ERK2 cascade3.79e-021.00e+004.6951118
GO:0061024membrane organization3.90e-021.00e+002.67525146
GO:0006259DNA metabolic process4.00e-021.00e+004.6171319
GO:0050840extracellular matrix binding4.00e-021.00e+004.6171119
GO:0048863stem cell differentiation4.00e-021.00e+004.6171119
GO:0032733positive regulation of interleukin-10 production4.00e-021.00e+004.6171119
GO:0055007cardiac muscle cell differentiation4.00e-021.00e+004.6171119
GO:0034113heterotypic cell-cell adhesion4.00e-021.00e+004.6171119
GO:0030866cortical actin cytoskeleton organization4.00e-021.00e+004.6171119
GO:0010628positive regulation of gene expression4.05e-021.00e+002.64624149
GO:0015078hydrogen ion transmembrane transporter activity4.21e-021.00e+004.5431320
GO:0090398cellular senescence4.21e-021.00e+004.5431120
GO:0005719nuclear euchromatin4.21e-021.00e+004.5431220
GO:0071364cellular response to epidermal growth factor stimulus4.41e-021.00e+004.4731121
GO:0005790smooth endoplasmic reticulum4.62e-021.00e+004.4061122
GO:0030863cortical cytoskeleton4.62e-021.00e+004.4061122
GO:0036464cytoplasmic ribonucleoprotein granule4.62e-021.00e+004.4061422
GO:0006270DNA replication initiation4.62e-021.00e+004.4061522
GO:0007052mitotic spindle organization4.62e-021.00e+004.4061222
GO:1900026positive regulation of substrate adhesion-dependent cell spreading4.82e-021.00e+004.3421223
GO:0043236laminin binding4.82e-021.00e+004.3421123
GO:0045787positive regulation of cell cycle4.82e-021.00e+004.3421123
GO:0008305integrin complex4.82e-021.00e+004.3421123
GO:0000398mRNA splicing, via spliceosome4.86e-021.00e+002.499212165
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding5.02e-021.00e+002.47325168
GO:0050766positive regulation of phagocytosis5.03e-021.00e+004.2801124
GO:0000794condensed nuclear chromosome5.03e-021.00e+004.2801224
GO:0006206pyrimidine nucleobase metabolic process5.03e-021.00e+004.2801224
GO:0042100B cell proliferation5.23e-021.00e+004.2211125
GO:0001968fibronectin binding5.23e-021.00e+004.2211125
GO:0022008neurogenesis5.23e-021.00e+004.2211125
GO:0042113B cell activation5.23e-021.00e+004.2211225
GO:0017144drug metabolic process5.23e-021.00e+004.2211125
GO:0032735positive regulation of interleukin-12 production5.23e-021.00e+004.2211125
GO:0035987endodermal cell differentiation5.43e-021.00e+004.1651126
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane5.43e-021.00e+004.1651126
GO:0004003ATP-dependent DNA helicase activity5.64e-021.00e+004.1101327
GO:0034080CENP-A containing nucleosome assembly5.64e-021.00e+004.1101227
GO:0019843rRNA binding5.64e-021.00e+004.1101327
GO:0007339binding of sperm to zona pellucida5.64e-021.00e+004.1101127
GO:0019904protein domain specific binding5.73e-021.00e+002.36526181
GO:0009897external side of plasma membrane5.84e-021.00e+002.34924183
GO:0015991ATP hydrolysis coupled proton transport5.84e-021.00e+004.0581428
GO:0043022ribosome binding5.84e-021.00e+004.0581328
GO:0019894kinesin binding5.84e-021.00e+004.0581128
GO:0003730mRNA 3'-UTR binding6.04e-021.00e+004.0071229
GO:0030669clathrin-coated endocytic vesicle membrane6.04e-021.00e+004.0071129
GO:0009986cell surface6.11e-021.00e+001.72939422
GO:0001618virus receptor activity6.24e-021.00e+003.9581130
GO:0034504protein localization to nucleus6.24e-021.00e+003.9581230
GO:0031623receptor internalization6.44e-021.00e+003.9111131
GO:0006271DNA strand elongation involved in DNA replication6.44e-021.00e+003.9111931
GO:0061077chaperone-mediated protein folding6.44e-021.00e+003.9111231
GO:0050661NADP binding6.65e-021.00e+003.8651132
GO:0015992proton transport6.65e-021.00e+003.8651332
GO:0034644cellular response to UV6.65e-021.00e+003.8651532
GO:0031072heat shock protein binding6.85e-021.00e+003.8211233
GO:0045335phagocytic vesicle6.85e-021.00e+003.8211233
GO:0008180COP9 signalosome7.05e-021.00e+003.7781134
GO:0051701interaction with host7.05e-021.00e+003.7781434
GO:0005876spindle microtubule7.05e-021.00e+003.7781334
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand7.25e-021.00e+003.7361235
GO:2001237negative regulation of extrinsic apoptotic signaling pathway7.25e-021.00e+003.7361135
GO:0042277peptide binding7.25e-021.00e+003.7361235
GO:0032588trans-Golgi network membrane7.45e-021.00e+003.6951136
GO:0034332adherens junction organization7.45e-021.00e+003.6951136
GO:0034446substrate adhesion-dependent cell spreading7.45e-021.00e+003.6951236
GO:0001895retina homeostasis7.45e-021.00e+003.6951136
GO:0032755positive regulation of interleukin-6 production7.45e-021.00e+003.6951236
GO:0005245voltage-gated calcium channel activity7.64e-021.00e+003.6561137
GO:0051084'de novo' posttranslational protein folding7.64e-021.00e+003.6561437
GO:0018107peptidyl-threonine phosphorylation7.64e-021.00e+003.6561137
GO:00515394 iron, 4 sulfur cluster binding7.64e-021.00e+003.6561337
GO:0045740positive regulation of DNA replication7.84e-021.00e+003.6171238
GO:0070527platelet aggregation7.84e-021.00e+003.6171238
GO:0090382phagosome maturation7.84e-021.00e+003.6171538
GO:0021766hippocampus development8.04e-021.00e+003.5801439
GO:0031490chromatin DNA binding8.04e-021.00e+003.5801239
GO:0006096glycolytic process8.04e-021.00e+003.5801439
GO:0032729positive regulation of interferon-gamma production8.04e-021.00e+003.5801239
GO:0032092positive regulation of protein binding8.04e-021.00e+003.5801339
GO:0007595lactation8.04e-021.00e+003.5801239
GO:0005622intracellular8.43e-021.00e+002.04525226
GO:0045785positive regulation of cell adhesion8.44e-021.00e+003.5081541
GO:0043195terminal bouton8.44e-021.00e+003.5081141
GO:0017148negative regulation of translation8.44e-021.00e+003.5081141
GO:0030521androgen receptor signaling pathway8.44e-021.00e+003.5081241
GO:0005902microvillus8.63e-021.00e+003.4731242
GO:0021987cerebral cortex development8.63e-021.00e+003.4731342
GO:0008380RNA splicing8.82e-021.00e+002.007213232
GO:0042110T cell activation8.83e-021.00e+003.4391343
GO:0014070response to organic cyclic compound8.83e-021.00e+003.4391343
GO:0048146positive regulation of fibroblast proliferation9.02e-021.00e+003.4061244
GO:0007286spermatid development9.02e-021.00e+003.4061144
GO:0006892post-Golgi vesicle-mediated transport9.02e-021.00e+003.4061244
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding9.02e-021.00e+003.4061244
GO:0005080protein kinase C binding9.02e-021.00e+003.4061144
GO:0015030Cajal body9.22e-021.00e+003.3731245
GO:0021762substantia nigra development9.42e-021.00e+003.3421146
GO:0030136clathrin-coated vesicle9.42e-021.00e+003.3421146
GO:0045665negative regulation of neuron differentiation9.42e-021.00e+003.3421246
GO:0044297cell body9.42e-021.00e+003.3421246
GO:0045727positive regulation of translation9.42e-021.00e+003.3421446
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity9.61e-021.00e+003.3111347
GO:0019003GDP binding9.80e-021.00e+003.2801248
GO:0001948glycoprotein binding1.02e-011.00e+003.2211350
GO:0016049cell growth1.02e-011.00e+003.2211150
GO:0035690cellular response to drug1.02e-011.00e+003.2211250
GO:0005905coated pit1.04e-011.00e+003.1931251
GO:0001669acrosomal vesicle1.04e-011.00e+003.1931151
GO:0000910cytokinesis1.04e-011.00e+003.1931151
GO:0003684damaged DNA binding1.04e-011.00e+003.19311151
GO:0006281DNA repair1.10e-011.00e+001.821222264
GO:0000226microtubule cytoskeleton organization1.12e-011.00e+003.0841355
GO:0002039p53 binding1.12e-011.00e+003.0841755
GO:0000932cytoplasmic mRNA processing body1.13e-011.00e+003.0581356
GO:0006879cellular iron ion homeostasis1.15e-011.00e+003.0321557
GO:0012505endomembrane system1.15e-011.00e+003.0321257
GO:0030097hemopoiesis1.17e-011.00e+003.0071358
GO:0002244hematopoietic progenitor cell differentiation1.17e-011.00e+003.0071158
GO:0007283spermatogenesis1.18e-011.00e+001.75726276
GO:0005840ribosome1.19e-011.00e+002.9831259
GO:0045216cell-cell junction organization1.19e-011.00e+002.9831259
GO:0005643nuclear pore1.19e-011.00e+002.9831459
GO:0031966mitochondrial membrane1.19e-011.00e+002.9831159
GO:0006987activation of signaling protein activity involved in unfolded protein response1.25e-011.00e+002.9111262
GO:0042995cell projection1.27e-011.00e+002.8881663
GO:0030141secretory granule1.34e-011.00e+002.7991267
GO:0006338chromatin remodeling1.36e-011.00e+002.7781468
GO:0003697single-stranded DNA binding1.38e-011.00e+002.7571969
GO:0034329cell junction assembly1.42e-011.00e+002.7151171
GO:0032587ruffle membrane1.44e-011.00e+002.6951472
GO:0003729mRNA binding1.45e-011.00e+002.6751473
GO:0000785chromatin1.45e-011.00e+002.6751573
GO:0055086nucleobase-containing small molecule metabolic process1.45e-011.00e+002.6751573
GO:0002020protease binding1.47e-011.00e+002.6561474
GO:0007265Ras protein signal transduction1.49e-011.00e+002.6361375
GO:0006874cellular calcium ion homeostasis1.51e-011.00e+002.6171176
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.53e-011.00e+002.5981577
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.53e-011.00e+002.5981677
GO:0007229integrin-mediated signaling pathway1.55e-011.00e+002.5801278
GO:0007411axon guidance1.55e-011.00e+001.51229327
GO:0006334nucleosome assembly1.56e-011.00e+002.5611479
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.58e-011.00e+002.5431280
GO:0007565female pregnancy1.58e-011.00e+002.5431280
GO:0043231intracellular membrane-bounded organelle1.59e-011.00e+001.49028332
GO:0030968endoplasmic reticulum unfolded protein response1.60e-011.00e+002.5251281
GO:0001889liver development1.62e-011.00e+002.5081382
GO:0001726ruffle1.62e-011.00e+002.5081482
GO:0006898receptor-mediated endocytosis1.69e-011.00e+002.4391286
GO:0007160cell-matrix adhesion1.73e-011.00e+002.4061388
GO:0003723RNA binding1.76e-011.00e+001.393219355
GO:0000922spindle pole1.78e-011.00e+002.3571491
GO:0018279protein N-linked glycosylation via asparagine1.78e-011.00e+002.3571291
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.80e-011.00e+002.3421492
GO:0006928cellular component movement1.80e-011.00e+002.3421792
GO:0005178integrin binding1.88e-011.00e+002.2651297
GO:0051726regulation of cell cycle1.97e-011.00e+002.19313102
GO:0007155cell adhesion1.99e-011.00e+001.28028384
GO:0070588calcium ion transmembrane transport2.04e-011.00e+002.13711106
GO:0014069postsynaptic density2.04e-011.00e+002.13711106
GO:0008284positive regulation of cell proliferation2.05e-011.00e+001.25028392
GO:0005815microtubule organizing center2.11e-011.00e+002.08414110
GO:0050900leukocyte migration2.13e-011.00e+002.07111111
GO:0006260DNA replication2.36e-011.00e+001.899112125
GO:0007050cell cycle arrest2.38e-011.00e+001.88817126
GO:0006511ubiquitin-dependent protein catabolic process2.39e-011.00e+001.87615127
GO:0030335positive regulation of cell migration2.44e-011.00e+001.84316130
GO:0016477cell migration2.46e-011.00e+001.83216131
GO:0031982vesicle2.51e-011.00e+001.799110134
GO:0007596blood coagulation2.62e-011.00e+001.007214464
GO:0007507heart development2.62e-011.00e+001.72615141
GO:0008286insulin receptor signaling pathway2.67e-011.00e+001.69516144
GO:0008017microtubule binding2.76e-011.00e+001.63617150
GO:0001666response to hypoxia2.76e-011.00e+001.63612150
GO:0030246carbohydrate binding2.78e-011.00e+001.62711151
GO:0045893positive regulation of transcription, DNA-templated2.81e-011.00e+000.937217487
GO:0005788endoplasmic reticulum lumen2.87e-011.00e+001.57111157
GO:0005769early endosome2.89e-011.00e+001.56112158
GO:0046777protein autophosphorylation2.89e-011.00e+001.56113158
GO:0005198structural molecule activity2.90e-011.00e+001.55214159
GO:0006397mRNA processing3.06e-011.00e+001.46413169
GO:0030424axon3.10e-011.00e+001.43913172
GO:0006886intracellular protein transport3.12e-011.00e+001.43114173
GO:0016607nuclear speck3.15e-011.00e+001.41414175
GO:0004672protein kinase activity3.19e-011.00e+001.38912178
GO:0031625ubiquitin protein ligase binding3.22e-011.00e+001.373113180
GO:0043687post-translational protein modification3.23e-011.00e+001.36514181
GO:0005578proteinaceous extracellular matrix3.26e-011.00e+001.34911183
GO:0001525angiogenesis3.51e-011.00e+001.22114200
GO:0005615extracellular space3.70e-011.00e+000.4703171010
GO:0005765lysosomal membrane3.76e-011.00e+001.09715218
GO:0005739mitochondrion3.91e-011.00e+000.4193241046
GO:0003713transcription coactivator activity4.04e-011.00e+000.964110239
GO:0005794Golgi apparatus4.09e-011.00e+000.521214650
GO:0043025neuronal cell body4.23e-011.00e+000.87614254
GO:0000166nucleotide binding4.45e-011.00e+000.77816272
GO:0005975carbohydrate metabolic process4.47e-011.00e+000.76715274
GO:0043065positive regulation of apoptotic process4.47e-011.00e+000.76718274
GO:0006357regulation of transcription from RNA polymerase II promoter4.49e-011.00e+000.76216275
GO:0042493response to drug4.64e-011.00e+000.695111288
GO:0019899enzyme binding4.64e-011.00e+000.695111288
GO:0007264small GTPase mediated signal transduction4.66e-011.00e+000.68513290
GO:0030198extracellular matrix organization4.72e-011.00e+000.66113295
GO:0005743mitochondrial inner membrane4.78e-011.00e+000.63615300
GO:0005856cytoskeleton4.90e-011.00e+000.58418311
GO:0003682chromatin binding5.15e-011.00e+000.481112334
GO:0005886plasma membrane5.83e-011.00e+00-0.0196382834
GO:0006508proteolysis5.90e-011.00e+000.18619410
GO:0045892negative regulation of transcription, DNA-templated6.02e-011.00e+000.137114424
GO:0055114oxidation-reduction process6.49e-011.00e+00-0.045111481
GO:0055085transmembrane transport6.74e-011.00e+00-0.14018514
GO:0008270zinc ion binding6.77e-011.00e+00-0.1942121067
GO:0048471perinuclear region of cytoplasm6.81e-011.00e+00-0.166112523
GO:0005509calcium ion binding7.24e-011.00e+00-0.33718589
GO:0000122negative regulation of transcription from RNA polymerase II promoter7.24e-011.00e+00-0.337112589
GO:0005783endoplasmic reticulum7.37e-011.00e+00-0.38819610
GO:0045087innate immune response7.40e-011.00e+00-0.402120616
GO:0003677DNA binding7.98e-011.00e+00-0.5352261351
GO:0045944positive regulation of transcription from RNA polymerase II promoter8.32e-011.00e+00-0.798119811
GO:0046872metal ion binding8.35e-011.00e+00-0.6522241465
GO:0006351transcription, DNA-templated8.67e-011.00e+00-0.7652251585
GO:0007165signal transduction8.78e-011.00e+00-1.027117950
GO:0005887integral component of plasma membrane8.81e-011.00e+00-1.04317961
GO:0005576extracellular region9.02e-011.00e+00-1.170191049
GO:0006355regulation of transcription, DNA-templated9.14e-011.00e+00-1.2431171104
GO:0016021integral component of membrane9.97e-011.00e+00-2.4131152483