reg-snw-9055

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.830	8.78e-07	2.82e-03	5.39e-03

wolf-screen-ratio-mammosphere-adherent-reg-snw-9055 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	Transcription factor	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	25	0.807	0.973	67	-	-	-
CCNA2	890	10	0.550	0.973	246	TF	Yes	-
RUVBL1	8607	24	0.720	0.973	126	TF	Yes	-
MCM5	4174	5	0.578	0.830	152	TF	Yes	-
EFTUD2	9343	17	0.883	0.956	30	-	Yes	-
HNRNPC	3183	40	1.812	0.973	62	-	Yes	-
[ PRC1 ]	9055	1	-0.336	0.830	55	-	-	-
TUBG1	7283	39	0.974	0.973	36	-	Yes	-
TACC3	10460	3	0.806	0.830	25	-	Yes	-

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CCNA2	890	RUVBL1	8607	pd	<>	reg.ITFP.txt: no annot
CAD	790	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
MCM5	4174	EFTUD2	9343	pd	>	reg.ITFP.txt: no annot
MCM5	4174	TACC3	10460	pd	>	reg.ITFP.txt: no annot
CAD	790	MCM5	4174	pd	<	reg.ITFP.txt: no annot
RUVBL1	8607	PRC1	9055	pd	>	reg.ITFP.txt: no annot
HNRNPC	3183	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot
MCM5	4174	PRC1	9055	pd	>	reg.ITFP.txt: no annot
CCNA2	890	PRC1	9055	pd	>	reg.ITFP.txt: no annot
TUBG1	7283	RUVBL1	8607	pd	<	reg.ITFP.txt: no annot

Related GO terms (139)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003678	DNA helicase activity	1.15e-04	1.00e+00	6.914	2	3	18
GO:0032508	DNA duplex unwinding	5.22e-04	1.00e+00	5.836	2	5	38
GO:0005654	nucleoplasm	5.32e-04	1.00e+00	2.631	5	55	876
GO:0031100	organ regeneration	7.00e-04	1.00e+00	5.624	2	2	44
GO:0004151	dihydroorotase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070335	aspartate binding	9.22e-04	1.00e+00	10.083	1	1	1
GO:0070409	carbamoyl phosphate biosynthetic process	9.22e-04	1.00e+00	10.083	1	1	1
GO:0005681	spliceosomal complex	1.09e-03	1.00e+00	5.302	2	2	55
GO:0071013	catalytic step 2 spliceosome	1.34e-03	1.00e+00	5.153	2	5	61
GO:0030953	astral microtubule organization	1.84e-03	1.00e+00	9.083	1	1	2
GO:0000022	mitotic spindle elongation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0016363	nuclear matrix	1.92e-03	1.00e+00	4.894	2	7	73
GO:0016020	membrane	2.35e-03	1.00e+00	2.168	5	38	1207
GO:0000278	mitotic cell cycle	2.39e-03	1.00e+00	3.374	3	35	314
GO:0005730	nucleolus	2.44e-03	1.00e+00	2.156	5	41	1217
GO:0006543	glutamine catabolic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	2.76e-03	1.00e+00	8.499	1	1	3
GO:0000086	G2/M transition of mitotic cell cycle	3.36e-03	1.00e+00	4.484	2	5	97
GO:0042802	identical protein binding	3.37e-03	1.00e+00	3.201	3	7	354
GO:0051414	response to cortisol	3.68e-03	1.00e+00	8.083	1	1	4
GO:0000212	meiotic spindle organization	3.68e-03	1.00e+00	8.083	1	1	4
GO:0006228	UTP biosynthetic process	3.68e-03	1.00e+00	8.083	1	1	4
GO:0001940	male pronucleus	3.68e-03	1.00e+00	8.083	1	1	4
GO:0014075	response to amine	4.60e-03	1.00e+00	7.762	1	1	5
GO:0005827	polar microtubule	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0001939	female pronucleus	4.60e-03	1.00e+00	7.762	1	1	5
GO:0003924	GTPase activity	5.01e-03	1.00e+00	4.189	2	3	119
GO:0046134	pyrimidine nucleoside biosynthetic process	5.52e-03	1.00e+00	7.499	1	1	6
GO:0031000	response to caffeine	5.52e-03	1.00e+00	7.499	1	1	6
GO:0042555	MCM complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0022027	interkinetic nuclear migration	5.52e-03	1.00e+00	7.499	1	1	6
GO:0005515	protein binding	5.67e-03	1.00e+00	1.074	8	76	4124
GO:0000398	mRNA splicing, via spliceosome	5.78e-03	1.00e+00	4.083	2	8	128
GO:0006184	GTP catabolic process	5.96e-03	1.00e+00	4.061	2	3	130
GO:0010389	regulation of G2/M transition of mitotic cell cycle	6.44e-03	1.00e+00	7.276	1	1	7
GO:0033762	response to glucagon	6.44e-03	1.00e+00	7.276	1	1	7
GO:0000812	Swr1 complex	6.44e-03	1.00e+00	7.276	1	2	7
GO:0031122	cytoplasmic microtubule organization	7.35e-03	1.00e+00	7.083	1	2	8
GO:0042994	cytoplasmic sequestering of transcription factor	7.35e-03	1.00e+00	7.083	1	1	8
GO:0031011	Ino80 complex	7.35e-03	1.00e+00	7.083	1	2	8
GO:0005634	nucleus	8.11e-03	1.00e+00	1.226	7	67	3246
GO:0032886	regulation of microtubule-based process	8.27e-03	1.00e+00	6.914	1	2	9
GO:0008266	poly(U) RNA binding	8.27e-03	1.00e+00	6.914	1	1	9
GO:0006541	glutamine metabolic process	9.18e-03	1.00e+00	6.762	1	1	10
GO:0043968	histone H2A acetylation	9.18e-03	1.00e+00	6.762	1	2	10
GO:0008380	RNA splicing	9.45e-03	1.00e+00	3.717	2	7	165
GO:0007067	mitotic nuclear division	9.45e-03	1.00e+00	3.717	2	8	165
GO:0007020	microtubule nucleation	1.01e-02	1.00e+00	6.624	1	1	11
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	2	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0035267	NuA4 histone acetyltransferase complex	1.10e-02	1.00e+00	6.499	1	3	12
GO:0007095	mitotic G2 DNA damage checkpoint	1.19e-02	1.00e+00	6.383	1	1	13
GO:0005525	GTP binding	1.33e-02	1.00e+00	3.461	2	5	197
GO:0005737	cytoplasm	1.47e-02	1.00e+00	1.306	6	50	2633
GO:0022008	neurogenesis	1.47e-02	1.00e+00	6.083	1	1	16
GO:0043234	protein complex	1.50e-02	1.00e+00	3.369	2	8	210
GO:0006206	pyrimidine nucleobase metabolic process	1.56e-02	1.00e+00	5.996	1	2	17
GO:0006270	DNA replication initiation	1.56e-02	1.00e+00	5.996	1	4	17
GO:0005813	centrosome	1.60e-02	1.00e+00	3.322	2	8	217
GO:0071364	cellular response to epidermal growth factor stimulus	1.65e-02	1.00e+00	5.914	1	1	18
GO:0071339	MLL1 complex	1.65e-02	1.00e+00	5.914	1	2	18
GO:0033574	response to testosterone	1.65e-02	1.00e+00	5.914	1	1	18
GO:0000794	condensed nuclear chromosome	1.65e-02	1.00e+00	5.914	1	3	18
GO:0019901	protein kinase binding	1.81e-02	1.00e+00	3.225	2	11	232
GO:0043044	ATP-dependent chromatin remodeling	1.83e-02	1.00e+00	5.762	1	2	20
GO:0034080	CENP-A containing nucleosome assembly	1.83e-02	1.00e+00	5.762	1	2	20
GO:0017144	drug metabolic process	1.92e-02	1.00e+00	5.691	1	1	21
GO:0043967	histone H4 acetylation	2.01e-02	1.00e+00	5.624	1	2	22
GO:0005876	spindle microtubule	2.19e-02	1.00e+00	5.499	1	2	24
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0031492	nucleosomal DNA binding	2.28e-02	1.00e+00	5.440	1	2	25
GO:0006271	DNA strand elongation involved in DNA replication	2.64e-02	1.00e+00	5.225	1	8	29
GO:0018107	peptidyl-threonine phosphorylation	2.64e-02	1.00e+00	5.225	1	2	29
GO:0021987	cerebral cortex development	2.73e-02	1.00e+00	5.177	1	2	30
GO:0043195	terminal bouton	2.82e-02	1.00e+00	5.129	1	1	31
GO:0015030	Cajal body	2.91e-02	1.00e+00	5.083	1	2	32
GO:0007595	lactation	2.91e-02	1.00e+00	5.083	1	2	32
GO:0000910	cytokinesis	3.00e-02	1.00e+00	5.039	1	1	33
GO:0048146	positive regulation of fibroblast proliferation	3.18e-02	1.00e+00	4.954	1	1	35
GO:0000226	microtubule cytoskeleton organization	3.27e-02	1.00e+00	4.914	1	2	36
GO:0040008	regulation of growth	3.36e-02	1.00e+00	4.874	1	2	37
GO:0035690	cellular response to drug	3.45e-02	1.00e+00	4.836	1	2	38
GO:0042995	cell projection	3.72e-02	1.00e+00	4.726	1	2	41
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	3.72e-02	1.00e+00	4.726	1	2	41
GO:0005524	ATP binding	4.20e-02	1.00e+00	1.868	3	23	892
GO:0030097	hemopoiesis	4.34e-02	1.00e+00	4.499	1	3	48
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	4.43e-02	1.00e+00	4.469	1	3	49
GO:0006310	DNA recombination	4.52e-02	1.00e+00	4.440	1	6	50
GO:0006334	nucleosome assembly	4.61e-02	1.00e+00	4.411	1	4	51
GO:0055086	nucleobase-containing small molecule metabolic process	4.61e-02	1.00e+00	4.411	1	5	51
GO:0032355	response to estradiol	5.13e-02	1.00e+00	4.251	1	1	57
GO:0007265	Ras protein signal transduction	5.31e-02	1.00e+00	4.201	1	3	59
GO:0007565	female pregnancy	5.75e-02	1.00e+00	4.083	1	2	64
GO:0000922	spindle pole	6.10e-02	1.00e+00	3.996	1	4	68
GO:0005200	structural constituent of cytoskeleton	6.10e-02	1.00e+00	3.996	1	2	68
GO:0006325	chromatin organization	6.27e-02	1.00e+00	3.954	1	3	70
GO:0001889	liver development	6.36e-02	1.00e+00	3.934	1	1	71
GO:0051726	regulation of cell cycle	6.53e-02	1.00e+00	3.894	1	2	73
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	2	74
GO:0015630	microtubule cytoskeleton	6.71e-02	1.00e+00	3.855	1	2	75
GO:0005815	microtubule organizing center	6.88e-02	1.00e+00	3.817	1	1	77
GO:0005819	spindle	7.14e-02	1.00e+00	3.762	1	4	80
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	4	82
GO:0006260	DNA replication	8.34e-02	1.00e+00	3.529	1	11	94
GO:0010467	gene expression	8.35e-02	1.00e+00	2.020	2	31	535
GO:0008017	microtubule binding	8.60e-02	1.00e+00	3.484	1	4	97
GO:0016887	ATPase activity	8.85e-02	1.00e+00	3.440	1	6	100
GO:0007507	heart development	9.36e-02	1.00e+00	3.356	1	1	106
GO:0046777	protein autophosphorylation	9.36e-02	1.00e+00	3.356	1	2	106
GO:0000790	nuclear chromatin	9.61e-02	1.00e+00	3.315	1	3	109
GO:0006397	mRNA processing	9.70e-02	1.00e+00	3.302	1	2	110
GO:0001666	response to hypoxia	1.02e-01	1.00e+00	3.225	1	1	116
GO:0016607	nuclear speck	1.07e-01	1.00e+00	3.153	1	3	122
GO:0004672	protein kinase activity	1.10e-01	1.00e+00	3.118	1	2	125
GO:0000082	G1/S transition of mitotic cell cycle	1.10e-01	1.00e+00	3.118	1	24	125
GO:0019904	protein domain specific binding	1.14e-01	1.00e+00	3.061	1	2	130
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	2	142
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0043025	neuronal cell body	1.47e-01	1.00e+00	2.666	1	3	171
GO:0000166	nucleotide binding	1.51e-01	1.00e+00	2.624	1	6	176
GO:0044822	poly(A) RNA binding	1.64e-01	1.00e+00	1.441	2	25	799
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.72e-01	1.00e+00	2.418	1	1	203
GO:0006281	DNA repair	1.72e-01	1.00e+00	2.418	1	19	203
GO:0019899	enzyme binding	1.78e-01	1.00e+00	2.369	1	4	210
GO:0070062	extracellular vesicular exosome	1.81e-01	1.00e+00	0.988	3	43	1641
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	7	218
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	11	247
GO:0005829	cytosol	2.18e-01	1.00e+00	0.865	3	58	1787
GO:0045893	positive regulation of transcription, DNA-templated	2.98e-01	1.00e+00	1.525	1	10	377
GO:0005794	Golgi apparatus	3.24e-01	1.00e+00	1.387	1	5	415
GO:0008270	zinc ion binding	5.02e-01	1.00e+00	0.578	1	7	727
GO:0044281	small molecule metabolic process	5.57e-01	1.00e+00	0.362	1	32	844
GO:0003677	DNA binding	6.01e-01	1.00e+00	0.196	1	18	947
GO:0006351	transcription, DNA-templated	6.50e-01	1.00e+00	0.012	1	9	1076
GO:0005886	plasma membrane	8.37e-01	1.00e+00	-0.717	1	11	1784

Wolf-ratios-Mammosphere-Adherent

reg-snw-9055

Statistics

Genes (9)

Interactions (10)

Related GO terms (139)