Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
int-snw-9527 | wolf-screen-ratio-mammosphere-adherent | 0.934 | 1.77e-15 | 2.52e-03 | 4.06e-02 | 10 | 9 |
reg-snw-2547 | wolf-screen-ratio-mammosphere-adherent | 0.862 | 2.49e-07 | 1.43e-03 | 2.94e-03 | 5 | 4 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | Transcription factor | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|---|
XRCC6 | 2547 | 2 | 0.031 | 0.862 | 63 | TF | - | - |
CLTC | 1213 | 56 | 0.884 | 1.138 | 247 | - | Yes | - |
RPL8 | 6132 | 24 | 0.778 | 0.874 | 234 | TF | Yes | - |
HNRNPC | 3183 | 108 | 1.812 | 0.973 | 181 | - | Yes | - |
RPL6 | 6128 | 37 | 0.844 | 1.113 | 164 | - | Yes | - |
RPL14 | 9045 | 49 | 1.250 | 1.113 | 166 | - | Yes | - |
TUBA1C | 84790 | 5 | 0.966 | 0.993 | 91 | - | Yes | - |
POLR2H | 5437 | 2 | 0.775 | 0.862 | 14 | - | Yes | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | - | Yes | - |
HSPD1 | 3329 | 70 | 0.913 | 1.035 | 325 | - | Yes | - |
GOSR1 | 9527 | 3 | -0.022 | 0.934 | 176 | - | - | - |
RPL11 | 6135 | 21 | 0.718 | 1.017 | 200 | - | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
ACTB | 60 | RPL11 | 6135 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | CLTC | 1213 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | HSPD1 | 3329 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow |
RPL14 | 9045 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
ACTB | 60 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
XRCC6 | 2547 | RPL8 | 6132 | pd | <> | reg.ITFP.txt: no annot |
RPL8 | 6132 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
RPL6 | 6128 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
XRCC6 | 2547 | HSPD1 | 3329 | pd | > | reg.ITFP.txt: no annot |
RPL11 | 6135 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
HNRNPC | 3183 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
RPL8 | 6132 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
RPL8 | 6132 | RPL11 | 6135 | pp | -- | int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium, IntAct_Yeast |
RPL11 | 6135 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
CLTC | 1213 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
XRCC6 | 2547 | POLR2H | 5437 | pd | > | reg.ITFP.txt: no annot |
XRCC6 | 2547 | HNRNPC | 3183 | pd | > | reg.ITFP.txt: no annot |
RPL6 | 6128 | RPL8 | 6132 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
ACTB | 60 | RPL6 | 6128 | pp | -- | int.I2D: BioGrid_Yeast |
CLTC | 1213 | XRCC6 | 2547 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: HPRD, IntAct, BIND, MINT; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
RPL6 | 6128 | RPL11 | 6135 | pp | -- | int.I2D: BioGrid_Yeast |
GOSR1 | 9527 | TUBA1C | 84790 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
HSPD1 | 3329 | GOSR1 | 9527 | pp | -- | int.I2D: BEHRENDS_AUTOPHAGY_LOW |
RPL6 | 6128 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0016020 | membrane | 1.03e-08 | 1.69e-04 | 2.962 | 10 | 80 | 1746 |
GO:0016032 | viral process | 2.86e-08 | 4.67e-04 | 4.140 | 7 | 55 | 540 |
GO:0022625 | cytosolic large ribosomal subunit | 3.49e-08 | 5.69e-04 | 6.795 | 4 | 5 | 49 |
GO:0044822 | poly(A) RNA binding | 1.38e-07 | 2.25e-03 | 3.335 | 8 | 50 | 1078 |
GO:0019083 | viral transcription | 2.70e-07 | 4.41e-03 | 6.070 | 4 | 8 | 81 |
GO:0006415 | translational termination | 3.61e-07 | 5.89e-03 | 5.967 | 4 | 8 | 87 |
GO:0005829 | cytosol | 4.35e-07 | 7.10e-03 | 2.408 | 10 | 125 | 2562 |
GO:0006414 | translational elongation | 4.72e-07 | 7.71e-03 | 5.870 | 4 | 11 | 93 |
GO:0044267 | cellular protein metabolic process | 5.97e-07 | 9.75e-03 | 4.043 | 6 | 24 | 495 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 7.40e-07 | 1.21e-02 | 5.709 | 4 | 8 | 104 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.07e-06 | 1.75e-02 | 5.577 | 4 | 10 | 114 |
GO:0019058 | viral life cycle | 1.11e-06 | 1.81e-02 | 5.564 | 4 | 10 | 115 |
GO:0006413 | translational initiation | 1.87e-06 | 3.05e-02 | 5.376 | 4 | 12 | 131 |
GO:0003735 | structural constituent of ribosome | 2.50e-06 | 4.09e-02 | 5.270 | 4 | 8 | 141 |
GO:0003723 | RNA binding | 3.31e-06 | 5.40e-02 | 4.260 | 5 | 19 | 355 |
GO:0010467 | gene expression | 3.47e-06 | 5.66e-02 | 3.609 | 6 | 58 | 669 |
GO:0016071 | mRNA metabolic process | 1.54e-05 | 2.52e-01 | 4.609 | 4 | 34 | 223 |
GO:0006412 | translation | 1.89e-05 | 3.09e-01 | 4.533 | 4 | 15 | 235 |
GO:0016070 | RNA metabolic process | 2.30e-05 | 3.76e-01 | 4.461 | 4 | 34 | 247 |
GO:0042273 | ribosomal large subunit biogenesis | 3.85e-05 | 6.28e-01 | 7.709 | 2 | 4 | 13 |
GO:0043234 | protein complex | 4.93e-05 | 8.05e-01 | 4.181 | 4 | 17 | 300 |
GO:0005925 | focal adhesion | 1.11e-04 | 1.00e+00 | 3.878 | 4 | 18 | 370 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.14e-04 | 1.00e+00 | 6.950 | 2 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.24e-04 | 1.00e+00 | 6.886 | 2 | 4 | 23 |
GO:0019843 | rRNA binding | 1.72e-04 | 1.00e+00 | 6.655 | 2 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 1.85e-04 | 1.00e+00 | 6.602 | 2 | 4 | 28 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.25e-04 | 1.00e+00 | 6.200 | 2 | 4 | 37 |
GO:0003725 | double-stranded RNA binding | 6.94e-04 | 1.00e+00 | 5.655 | 2 | 6 | 54 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 6.94e-04 | 1.00e+00 | 5.655 | 2 | 5 | 54 |
GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0048291 | isotype switching to IgG isotypes | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0002368 | B cell cytokine production | 7.35e-04 | 1.00e+00 | 10.409 | 1 | 1 | 1 |
GO:0032481 | positive regulation of type I interferon production | 8.85e-04 | 1.00e+00 | 5.479 | 2 | 6 | 61 |
GO:0043564 | Ku70:Ku80 complex | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0071475 | cellular hyperosmotic salinity response | 1.47e-03 | 1.00e+00 | 9.409 | 1 | 1 | 2 |
GO:0005200 | structural constituent of cytoskeleton | 2.04e-03 | 1.00e+00 | 4.870 | 2 | 7 | 93 |
GO:0001649 | osteoblast differentiation | 2.13e-03 | 1.00e+00 | 4.840 | 2 | 6 | 95 |
GO:0006364 | rRNA processing | 2.17e-03 | 1.00e+00 | 4.825 | 2 | 5 | 96 |
GO:1900126 | negative regulation of hyaluronan biosynthetic process | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0006458 | 'de novo' protein folding | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0030135 | coated vesicle | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0071439 | clathrin complex | 2.20e-03 | 1.00e+00 | 8.825 | 1 | 1 | 3 |
GO:0032051 | clathrin light chain binding | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 2 | 4 |
GO:1903077 | negative regulation of protein localization to plasma membrane | 2.94e-03 | 1.00e+00 | 8.409 | 1 | 1 | 4 |
GO:0006266 | DNA ligation | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0003691 | double-stranded telomeric DNA binding | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0071481 | cellular response to X-ray | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0046696 | lipopolysaccharide receptor complex | 3.67e-03 | 1.00e+00 | 8.088 | 1 | 1 | 5 |
GO:0000790 | nuclear chromatin | 4.12e-03 | 1.00e+00 | 4.354 | 2 | 7 | 133 |
GO:0031982 | vesicle | 4.18e-03 | 1.00e+00 | 4.343 | 2 | 10 | 134 |
GO:0070419 | nonhomologous end joining complex | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0003688 | DNA replication origin binding | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 4 | 6 |
GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0030118 | clathrin coat | 4.40e-03 | 1.00e+00 | 7.825 | 1 | 1 | 6 |
GO:0061024 | membrane organization | 4.95e-03 | 1.00e+00 | 4.220 | 2 | 5 | 146 |
GO:0030132 | clathrin coat of coated pit | 5.14e-03 | 1.00e+00 | 7.602 | 1 | 1 | 7 |
GO:0006457 | protein folding | 5.15e-03 | 1.00e+00 | 4.190 | 2 | 8 | 149 |
GO:0070062 | extracellular vesicular exosome | 5.32e-03 | 1.00e+00 | 1.698 | 6 | 98 | 2516 |
GO:0005198 | structural molecule activity | 5.84e-03 | 1.00e+00 | 4.097 | 2 | 4 | 159 |
GO:0001055 | RNA polymerase II activity | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 3 | 8 |
GO:0075713 | establishment of integrated proviral latency | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 5.87e-03 | 1.00e+00 | 7.409 | 1 | 1 | 8 |
GO:0000398 | mRNA splicing, via spliceosome | 6.27e-03 | 1.00e+00 | 4.043 | 2 | 12 | 165 |
GO:0005654 | nucleoplasm | 6.45e-03 | 1.00e+00 | 2.313 | 4 | 83 | 1095 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 6.50e-03 | 1.00e+00 | 4.017 | 2 | 5 | 168 |
GO:0000783 | nuclear telomere cap complex | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 9 |
GO:0033151 | V(D)J recombination | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 9 |
GO:0043032 | positive regulation of macrophage activation | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 1 | 10 |
GO:0051604 | protein maturation | 7.33e-03 | 1.00e+00 | 7.088 | 1 | 1 | 10 |
GO:0032727 | positive regulation of interferon-alpha production | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 1 | 11 |
GO:0001054 | RNA polymerase I activity | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 3 | 11 |
GO:0045120 | pronucleus | 8.06e-03 | 1.00e+00 | 6.950 | 1 | 1 | 11 |
GO:0005736 | DNA-directed RNA polymerase I complex | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 3 | 12 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 8.79e-03 | 1.00e+00 | 6.825 | 1 | 2 | 12 |
GO:0045087 | innate immune response | 9.12e-03 | 1.00e+00 | 2.728 | 3 | 20 | 616 |
GO:0001530 | lipopolysaccharide binding | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 2 | 13 |
GO:0008266 | poly(U) RNA binding | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 13 |
GO:0051131 | chaperone-mediated protein complex assembly | 9.52e-03 | 1.00e+00 | 6.709 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.02e-02 | 1.00e+00 | 6.602 | 1 | 4 | 14 |
GO:0030705 | cytoskeleton-dependent intracellular transport | 1.02e-02 | 1.00e+00 | 6.602 | 1 | 1 | 14 |
GO:0042026 | protein refolding | 1.10e-02 | 1.00e+00 | 6.503 | 1 | 2 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.17e-02 | 1.00e+00 | 6.409 | 1 | 1 | 16 |
GO:0005665 | DNA-directed RNA polymerase II, core complex | 1.17e-02 | 1.00e+00 | 6.409 | 1 | 4 | 16 |
GO:0001056 | RNA polymerase III activity | 1.17e-02 | 1.00e+00 | 6.409 | 1 | 3 | 16 |
GO:0008380 | RNA splicing | 1.21e-02 | 1.00e+00 | 3.551 | 2 | 13 | 232 |
GO:0005666 | DNA-directed RNA polymerase III complex | 1.24e-02 | 1.00e+00 | 6.322 | 1 | 3 | 17 |
GO:0050870 | positive regulation of T cell activation | 1.24e-02 | 1.00e+00 | 6.322 | 1 | 1 | 17 |
GO:0006891 | intra-Golgi vesicle-mediated transport | 1.24e-02 | 1.00e+00 | 6.322 | 1 | 1 | 17 |
GO:0006386 | termination of RNA polymerase III transcription | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 3 | 18 |
GO:0006385 | transcription elongation from RNA polymerase III promoter | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 3 | 18 |
GO:0006303 | double-strand break repair via nonhomologous end joining | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 3 | 18 |
GO:0032733 | positive regulation of interleukin-10 production | 1.39e-02 | 1.00e+00 | 6.162 | 1 | 1 | 19 |
GO:0050769 | positive regulation of neurogenesis | 1.39e-02 | 1.00e+00 | 6.162 | 1 | 1 | 19 |
GO:0006281 | DNA repair | 1.55e-02 | 1.00e+00 | 3.365 | 2 | 22 | 264 |
GO:0030863 | cortical cytoskeleton | 1.61e-02 | 1.00e+00 | 5.950 | 1 | 1 | 22 |
GO:0006362 | transcription elongation from RNA polymerase I promoter | 1.68e-02 | 1.00e+00 | 5.886 | 1 | 3 | 23 |
GO:0006363 | termination of RNA polymerase I transcription | 1.75e-02 | 1.00e+00 | 5.825 | 1 | 3 | 24 |
GO:0005484 | SNAP receptor activity | 1.75e-02 | 1.00e+00 | 5.825 | 1 | 2 | 24 |
GO:0042100 | B cell proliferation | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 25 |
GO:0042113 | B cell activation | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 2 | 25 |
GO:0032735 | positive regulation of interleukin-12 production | 1.82e-02 | 1.00e+00 | 5.766 | 1 | 1 | 25 |
GO:0006361 | transcription initiation from RNA polymerase I promoter | 1.90e-02 | 1.00e+00 | 5.709 | 1 | 3 | 26 |
GO:0004003 | ATP-dependent DNA helicase activity | 1.97e-02 | 1.00e+00 | 5.655 | 1 | 3 | 27 |
GO:0051258 | protein polymerization | 1.97e-02 | 1.00e+00 | 5.655 | 1 | 2 | 27 |
GO:0007017 | microtubule-based process | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 3 | 28 |
GO:0019894 | kinesin binding | 2.04e-02 | 1.00e+00 | 5.602 | 1 | 1 | 28 |
GO:0003730 | mRNA 3'-UTR binding | 2.11e-02 | 1.00e+00 | 5.551 | 1 | 2 | 29 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 2.11e-02 | 1.00e+00 | 5.551 | 1 | 1 | 29 |
GO:0006360 | transcription from RNA polymerase I promoter | 2.18e-02 | 1.00e+00 | 5.503 | 1 | 4 | 30 |
GO:0006370 | 7-methylguanosine mRNA capping | 2.18e-02 | 1.00e+00 | 5.503 | 1 | 4 | 30 |
GO:0034504 | protein localization to nucleus | 2.18e-02 | 1.00e+00 | 5.503 | 1 | 2 | 30 |
GO:0019901 | protein kinase binding | 2.22e-02 | 1.00e+00 | 3.088 | 2 | 21 | 320 |
GO:0031201 | SNARE complex | 2.26e-02 | 1.00e+00 | 5.455 | 1 | 2 | 31 |
GO:0031623 | receptor internalization | 2.26e-02 | 1.00e+00 | 5.455 | 1 | 1 | 31 |
GO:0033572 | transferrin transport | 2.33e-02 | 1.00e+00 | 5.409 | 1 | 6 | 32 |
GO:0005801 | cis-Golgi network | 2.54e-02 | 1.00e+00 | 5.280 | 1 | 1 | 35 |
GO:0032588 | trans-Golgi network membrane | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 36 |
GO:0034332 | adherens junction organization | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 36 |
GO:0001895 | retina homeostasis | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 36 |
GO:0006605 | protein targeting | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 2 | 36 |
GO:0032755 | positive regulation of interleukin-6 production | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 2 | 36 |
GO:0070527 | platelet aggregation | 2.76e-02 | 1.00e+00 | 5.162 | 1 | 2 | 38 |
GO:0032729 | positive regulation of interferon-gamma production | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 2 | 39 |
GO:0006383 | transcription from RNA polymerase III promoter | 2.83e-02 | 1.00e+00 | 5.124 | 1 | 3 | 39 |
GO:0005881 | cytoplasmic microtubule | 2.97e-02 | 1.00e+00 | 5.052 | 1 | 2 | 41 |
GO:0042147 | retrograde transport, endosome to Golgi | 3.05e-02 | 1.00e+00 | 5.017 | 1 | 3 | 42 |
GO:0032508 | DNA duplex unwinding | 3.05e-02 | 1.00e+00 | 5.017 | 1 | 4 | 42 |
GO:0042110 | T cell activation | 3.12e-02 | 1.00e+00 | 4.983 | 1 | 3 | 43 |
GO:0050434 | positive regulation of viral transcription | 3.19e-02 | 1.00e+00 | 4.950 | 1 | 5 | 44 |
GO:0006892 | post-Golgi vesicle-mediated transport | 3.19e-02 | 1.00e+00 | 4.950 | 1 | 2 | 44 |
GO:0021762 | substantia nigra development | 3.33e-02 | 1.00e+00 | 4.886 | 1 | 1 | 46 |
GO:0030136 | clathrin-coated vesicle | 3.33e-02 | 1.00e+00 | 4.886 | 1 | 1 | 46 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.33e-02 | 1.00e+00 | 4.886 | 1 | 8 | 46 |
GO:0006986 | response to unfolded protein | 3.69e-02 | 1.00e+00 | 4.737 | 1 | 2 | 51 |
GO:0005905 | coated pit | 3.69e-02 | 1.00e+00 | 4.737 | 1 | 2 | 51 |
GO:0003684 | damaged DNA binding | 3.69e-02 | 1.00e+00 | 4.737 | 1 | 11 | 51 |
GO:0005515 | protein binding | 3.92e-02 | 1.00e+00 | 0.829 | 8 | 172 | 6127 |
GO:0002039 | p53 binding | 3.97e-02 | 1.00e+00 | 4.628 | 1 | 7 | 55 |
GO:0006888 | ER to Golgi vesicle-mediated transport | 3.97e-02 | 1.00e+00 | 4.628 | 1 | 2 | 55 |
GO:0051087 | chaperone binding | 4.25e-02 | 1.00e+00 | 4.527 | 1 | 6 | 59 |
GO:0000723 | telomere maintenance | 4.25e-02 | 1.00e+00 | 4.527 | 1 | 8 | 59 |
GO:0045216 | cell-cell junction organization | 4.25e-02 | 1.00e+00 | 4.527 | 1 | 2 | 59 |
GO:0006302 | double-strand break repair | 4.47e-02 | 1.00e+00 | 4.455 | 1 | 8 | 62 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 4.82e-02 | 1.00e+00 | 4.343 | 1 | 6 | 67 |
GO:0030141 | secretory granule | 4.82e-02 | 1.00e+00 | 4.343 | 1 | 2 | 67 |
GO:0006289 | nucleotide-excision repair | 4.96e-02 | 1.00e+00 | 4.301 | 1 | 12 | 69 |
GO:0003697 | single-stranded DNA binding | 4.96e-02 | 1.00e+00 | 4.301 | 1 | 9 | 69 |
GO:0034329 | cell junction assembly | 5.10e-02 | 1.00e+00 | 4.260 | 1 | 1 | 71 |
GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 5.52e-02 | 1.00e+00 | 4.143 | 1 | 6 | 77 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 5.52e-02 | 1.00e+00 | 4.143 | 1 | 5 | 77 |
GO:0071013 | catalytic step 2 spliceosome | 5.66e-02 | 1.00e+00 | 4.106 | 1 | 7 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 5.73e-02 | 1.00e+00 | 4.088 | 1 | 2 | 80 |
GO:0051301 | cell division | 5.80e-02 | 1.00e+00 | 4.070 | 1 | 6 | 81 |
GO:0005681 | spliceosomal complex | 5.94e-02 | 1.00e+00 | 4.034 | 1 | 3 | 83 |
GO:0006898 | receptor-mediated endocytosis | 6.15e-02 | 1.00e+00 | 3.983 | 1 | 2 | 86 |
GO:0003690 | double-stranded DNA binding | 6.49e-02 | 1.00e+00 | 3.902 | 1 | 4 | 91 |
GO:0050821 | protein stabilization | 6.49e-02 | 1.00e+00 | 3.902 | 1 | 2 | 91 |
GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II | 6.56e-02 | 1.00e+00 | 3.886 | 1 | 4 | 92 |
GO:0042470 | melanosome | 6.56e-02 | 1.00e+00 | 3.886 | 1 | 10 | 92 |
GO:0006928 | cellular component movement | 6.56e-02 | 1.00e+00 | 3.886 | 1 | 7 | 92 |
GO:0051082 | unfolded protein binding | 6.77e-02 | 1.00e+00 | 3.840 | 1 | 6 | 95 |
GO:0003677 | DNA binding | 7.08e-02 | 1.00e+00 | 1.595 | 3 | 26 | 1351 |
GO:0005524 | ATP binding | 7.12e-02 | 1.00e+00 | 1.591 | 3 | 46 | 1354 |
GO:0014069 | postsynaptic density | 7.52e-02 | 1.00e+00 | 3.682 | 1 | 1 | 106 |
GO:0030529 | ribonucleoprotein complex | 8.07e-02 | 1.00e+00 | 3.577 | 1 | 8 | 114 |
GO:0005819 | spindle | 8.07e-02 | 1.00e+00 | 3.577 | 1 | 7 | 114 |
GO:0072562 | blood microparticle | 8.21e-02 | 1.00e+00 | 3.551 | 1 | 4 | 116 |
GO:0006325 | chromatin organization | 8.68e-02 | 1.00e+00 | 3.467 | 1 | 4 | 123 |
GO:0016887 | ATPase activity | 1.01e-01 | 1.00e+00 | 3.240 | 1 | 7 | 144 |
GO:0005769 | early endosome | 1.10e-01 | 1.00e+00 | 3.106 | 1 | 2 | 158 |
GO:0008022 | protein C-terminus binding | 1.12e-01 | 1.00e+00 | 3.079 | 1 | 4 | 161 |
GO:0007420 | brain development | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 1 | 172 |
GO:0005730 | nucleolus | 1.19e-01 | 1.00e+00 | 1.277 | 3 | 70 | 1684 |
GO:0030424 | axon | 1.19e-01 | 1.00e+00 | 2.983 | 1 | 3 | 172 |
GO:0044212 | transcription regulatory region DNA binding | 1.19e-01 | 1.00e+00 | 2.992 | 1 | 6 | 171 |
GO:0006886 | intracellular protein transport | 1.20e-01 | 1.00e+00 | 2.975 | 1 | 4 | 173 |
GO:0005667 | transcription factor complex | 1.23e-01 | 1.00e+00 | 2.934 | 1 | 6 | 178 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.27e-01 | 1.00e+00 | 2.886 | 1 | 8 | 184 |
GO:0003924 | GTPase activity | 1.40e-01 | 1.00e+00 | 2.744 | 1 | 9 | 203 |
GO:0006184 | GTP catabolic process | 1.50e-01 | 1.00e+00 | 2.628 | 1 | 9 | 220 |
GO:0007067 | mitotic nuclear division | 1.57e-01 | 1.00e+00 | 2.558 | 1 | 13 | 231 |
GO:0005759 | mitochondrial matrix | 1.59e-01 | 1.00e+00 | 2.545 | 1 | 12 | 233 |
GO:0005615 | extracellular space | 1.68e-01 | 1.00e+00 | 1.429 | 2 | 17 | 1010 |
GO:0005874 | microtubule | 1.74e-01 | 1.00e+00 | 2.398 | 1 | 6 | 258 |
GO:0000166 | nucleotide binding | 1.83e-01 | 1.00e+00 | 2.322 | 1 | 6 | 272 |
GO:0043065 | positive regulation of apoptotic process | 1.84e-01 | 1.00e+00 | 2.311 | 1 | 8 | 274 |
GO:0005743 | mitochondrial inner membrane | 2.00e-01 | 1.00e+00 | 2.181 | 1 | 5 | 300 |
GO:0006200 | ATP catabolic process | 2.01e-01 | 1.00e+00 | 2.166 | 1 | 14 | 303 |
GO:0005856 | cytoskeleton | 2.06e-01 | 1.00e+00 | 2.129 | 1 | 8 | 311 |
GO:0007411 | axon guidance | 2.16e-01 | 1.00e+00 | 2.056 | 1 | 9 | 327 |
GO:0005525 | GTP binding | 2.16e-01 | 1.00e+00 | 2.052 | 1 | 11 | 328 |
GO:0015031 | protein transport | 2.33e-01 | 1.00e+00 | 1.930 | 1 | 4 | 357 |
GO:0000139 | Golgi membrane | 2.62e-01 | 1.00e+00 | 1.737 | 1 | 2 | 408 |
GO:0005634 | nucleus | 2.65e-01 | 1.00e+00 | 0.494 | 5 | 131 | 4828 |
GO:0009986 | cell surface | 2.70e-01 | 1.00e+00 | 1.688 | 1 | 9 | 422 |
GO:0045892 | negative regulation of transcription, DNA-templated | 2.71e-01 | 1.00e+00 | 1.682 | 1 | 14 | 424 |
GO:0006366 | transcription from RNA polymerase II promoter | 2.71e-01 | 1.00e+00 | 1.678 | 1 | 12 | 425 |
GO:0043066 | negative regulation of apoptotic process | 2.76e-01 | 1.00e+00 | 1.651 | 1 | 30 | 433 |
GO:0007596 | blood coagulation | 2.93e-01 | 1.00e+00 | 1.551 | 1 | 14 | 464 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.05e-01 | 1.00e+00 | 1.482 | 1 | 17 | 487 |
GO:0042802 | identical protein binding | 3.07e-01 | 1.00e+00 | 1.470 | 1 | 18 | 491 |
GO:0005794 | Golgi apparatus | 3.86e-01 | 1.00e+00 | 1.065 | 1 | 14 | 650 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 4.58e-01 | 1.00e+00 | 0.746 | 1 | 19 | 811 |
GO:0005739 | mitochondrion | 5.48e-01 | 1.00e+00 | 0.379 | 1 | 24 | 1046 |
GO:0006355 | regulation of transcription, DNA-templated | 5.69e-01 | 1.00e+00 | 0.301 | 1 | 17 | 1104 |
GO:0005737 | cytoplasm | 5.89e-01 | 1.00e+00 | 0.037 | 3 | 98 | 3976 |
GO:0005886 | plasma membrane | 6.43e-01 | 1.00e+00 | -0.059 | 2 | 38 | 2834 |
GO:0006351 | transcription, DNA-templated | 7.07e-01 | 1.00e+00 | -0.221 | 1 | 25 | 1585 |
GO:0016021 | integral component of membrane | 8.62e-01 | 1.00e+00 | -0.868 | 1 | 15 | 2483 |