meta-reg-snw-1994

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-1455 wolf-screen-ratio-mammosphere-adherent 0.994 6.85e-18 6.35e-04 1.46e-02 16 15
reg-snw-1994 wolf-screen-ratio-mammosphere-adherent 0.809 1.87e-06 4.21e-03 7.70e-03 6 6
int-snw-811 wolf-screen-ratio-mammosphere-adherent 0.932 2.10e-15 2.63e-03 4.19e-02 24 22
wolf-screen-ratio-mammosphere-adherent-meta-reg-snw-1994 subnetwork

Genes (34)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA3 5684 900.5330.815238Yes-
DDX18 8886 250.6601.013215Yes-
PSMA2 5683 1121.0931.106108Yes-
LPIN3 64900 8-0.6250.99439-Yes
ADH5 128 160.6330.99443Yes-
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
CALR 811 38-0.4180.93279-Yes
RSL24D1 51187 381.3001.02059Yes-
PSMD1 5707 860.8360.830118Yes-
EIF2S2 8894 391.0750.940103Yes-
EEF2 1938 640.8901.043301Yes-
RPS11 6205 620.9931.113175Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD11 5717 1241.0951.106218Yes-
RAN 5901 890.6320.899258Yes-
HSPD1 3329 700.9131.035325Yes-
CSNK1G2 1455 8-0.0840.99490--
RBX1 9978 1151.1850.934148Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
OGDH 4967 720.8470.802126Yes-
RPSA 3921 1201.3271.151152Yes-
PGD 5226 891.2011.106152Yes-
PSMD13 5719 560.8480.801114Yes-
ELAVL1 1994 30.5170.809215Yes-
PSMD3 5709 1000.9861.106201Yes-
CLTC 1213 560.8841.138247Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
ITGAV 3685 390.5560.94937--
PSMD6 9861 790.8480.878143Yes-
PSMC1 5700 510.8401.018137Yes-

Interactions (123)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
PSMD11 5717 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
ADH5 128 DDX18 8886 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
PSMA1 5682 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
PSMA2 5683 PSMD13 5719 pp -- int.I2D: YeastLow
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
ACTB 60 CLTC 1213 pp -- int.I2D: IntAct_Yeast
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMD1 5707 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
PSMC1 5700 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
PGD 5226 RAN 5901 pp -- int.I2D: YeastLow
CLTC 1213 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
ELAVL1 1994 PSMB2 5690 pd > reg.ITFP.txt: no annot
ACTB 60 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, YeastMedium
CALR 811 PSMA3 5684 pp -- int.I2D: BioGrid
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
CSNK1G2 1455 PSMA3 5684 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
PSMC1 5700 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core
PSMA1 5682 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastMedium
ELAVL1 1994 RAN 5901 pd > reg.ITFP.txt: no annot
CALR 811 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB 60 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
CLTC 1213 EIF2S2 8894 pp -- int.I2D: YeastLow
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
CSNK1G2 1455 DDX18 8886 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
OGDH 4967 PSMD13 5719 pp -- int.I2D: YeastLow
OGDH 4967 PSMD6 9861 pp -- int.I2D: YeastLow
EEF2 1938 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
PSMD11 5717 DDX18 8886 pp -- int.I2D: YeastLow
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ADH5 128 CSNK1G2 1455 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow
PSMC1 5700 PSMD1 5707 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, Krogan_Core, MINT_Yeast
PSMD1 5707 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
OGDH 4967 DDX18 8886 pp -- int.I2D: YeastLow
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
CAD 790 LPIN3 64900 pp -- int.I2D: IntAct_Yeast
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3 5709 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast
PSMC1 5700 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, BioGrid, IntAct_Yeast, Krogan_Core, YeastHigh
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMC1 5700 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 DDX18 8886 pp -- int.I2D: YeastLow
PSMA3 5684 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
OGDH 4967 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD6 9861 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
DDX18 8886 RSL24D1 51187 pp -- int.I2D: YeastLow, BioGrid_Yeast
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
CALR 811 ITGAV 3685 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro, in vivo
PSMB7 5695 PSMD13 5719 pd < reg.ITFP.txt: no annot
ELAVL1 1994 DDX18 8886 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB2 5690 PSMD6 9861 pp -- int.I2D: BioGrid_Yeast, YeastMedium
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 RAN 5901 pp -- int.I2D: YeastLow
HSPD1 3329 OGDH 4967 pp -- int.I2D: YeastLow
EEF2 1938 PSMD13 5719 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
OGDH 4967 PSMC1 5700 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD6 9861 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid
PSMA1 5682 PSMC1 5700 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct
PSMD11 5717 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG
PSMD3 5709 PSMD13 5719 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
PSMD13 5719 PSMD6 9861 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core
RPSA 3921 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD 5226 DDX18 8886 pp -- int.I2D: YeastLow
RPS11 6205 DDX18 8886 pp -- int.I2D: BioGrid_Yeast
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMB2 5690 PSMC1 5700 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
CSNK1G2 1455 LPIN3 64900 pp -- int.I2D: BioGrid_Yeast, Yeast_Kinome
PSMD11 5717 EIF2S2 8894 pd > reg.ITFP.txt: no annot
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (481)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent8.00e-231.30e-186.418132373
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.69e-222.77e-186.341132377
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.72e-214.44e-176.053132394
GO:0006521regulation of cellular amino acid metabolic process1.86e-203.03e-166.723112150
GO:0000502proteasome complex1.12e-191.83e-156.508112258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle4.37e-197.13e-156.344112465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest4.37e-197.13e-156.344112265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.05e-181.71e-146.237112470
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.02e-183.29e-146.157112474
GO:0010467gene expression3.55e-185.80e-143.7691958669
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process4.33e-187.07e-146.063112579
GO:0016071mRNA metabolic process5.73e-189.36e-144.9131434223
GO:0016070RNA metabolic process2.43e-173.97e-134.7661434247
GO:0000082G1/S transition of mitotic cell cycle1.07e-161.75e-125.2631233150
GO:0042981regulation of apoptotic process1.16e-161.90e-125.2541226151
GO:0000209protein polyubiquitination3.59e-165.86e-125.5081121116
GO:0034641cellular nitrogen compound metabolic process8.10e-161.32e-115.0241225177
GO:0016032viral process2.11e-153.44e-113.8301655540
GO:0005829cytosol5.50e-158.98e-112.284261252562
GO:0005654nucleoplasm5.22e-138.52e-092.98018831095
GO:0022624proteasome accessory complex6.24e-131.02e-087.4046917
GO:0016020membrane8.62e-131.41e-082.52921801746
GO:0070062extracellular vesicular exosome9.69e-121.58e-072.13423982516
GO:0000278mitotic cell cycle1.27e-112.07e-073.8551252398
GO:0005838proteasome regulatory particle2.26e-113.69e-077.6445712
GO:0043066negative regulation of apoptotic process3.38e-115.51e-073.7341230433
GO:0044281small molecule metabolic process1.12e-101.83e-062.65617571295
GO:0005839proteasome core complex2.42e-103.96e-067.05951118
GO:0004298threonine-type endopeptidase activity4.37e-107.14e-066.90751120
GO:0006915apoptotic process1.20e-081.96e-043.2091134571
GO:0044822poly(A) RNA binding1.07e-071.74e-032.53313501078
GO:0019773proteasome core complex, alpha-subunit complex4.59e-077.50e-037.492358
GO:0005844polysome1.84e-053.00e-015.8483425
GO:0005515protein binding9.31e-051.00e+000.911241726127
GO:0005634nucleus9.78e-051.00e+001.062211314828
GO:0003725double-stranded RNA binding1.91e-041.00e+004.7373654
GO:0051087chaperone binding2.48e-041.00e+004.6093659
GO:00709353'-UTR-mediated mRNA stabilization2.74e-041.00e+006.3222212
GO:0030234enzyme regulator activity3.24e-041.00e+006.2072313
GO:0043234protein complex3.65e-041.00e+003.000517300
GO:0044267cellular protein metabolic process4.93e-041.00e+002.541624495
GO:0042176regulation of protein catabolic process4.96e-041.00e+005.9072316
GO:0006414translational elongation9.43e-041.00e+003.95331193
GO:0005925focal adhesion9.44e-041.00e+002.698518370
GO:0033574response to testosterone9.48e-041.00e+005.4482222
GO:0001649osteoblast differentiation1.00e-031.00e+003.9223695
GO:0043044ATP-dependent chromatin remodeling1.04e-031.00e+005.3832423
GO:0006611protein export from nucleus1.23e-031.00e+005.2632425
GO:0006412translation1.38e-031.00e+003.030415235
GO:0031492nucleosomal DNA binding1.54e-031.00e+005.1002428
GO:0003730mRNA 3'-UTR binding1.65e-031.00e+005.0492229
GO:0005730nucleolus1.71e-031.00e+001.51110701684
GO:0019058viral life cycle1.74e-031.00e+003.646310115
GO:0002842positive regulation of T cell mediated immune response to tumor cell2.08e-031.00e+008.907111
GO:0002502peptide antigen assembly with MHC class I protein complex2.08e-031.00e+008.907111
GO:0018467formaldehyde dehydrogenase activity2.08e-031.00e+008.907111
GO:0035867alphav-beta3 integrin-IGF-1-IGF1R complex2.08e-031.00e+008.907111
GO:0048291isotype switching to IgG isotypes2.08e-031.00e+008.907111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.08e-031.00e+008.907111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity2.08e-031.00e+008.907111
GO:0070335aspartate binding2.08e-031.00e+008.907111
GO:0052066entry of symbiont into host cell by promotion of host phagocytosis2.08e-031.00e+008.907111
GO:0051903S-(hydroxymethyl)glutathione dehydrogenase activity2.08e-031.00e+008.907111
GO:2000425regulation of apoptotic cell clearance2.08e-031.00e+008.907111
GO:0004151dihydroorotase activity2.08e-031.00e+008.907111
GO:0019521D-gluconate metabolic process2.08e-031.00e+008.907111
GO:0004070aspartate carbamoyltransferase activity2.08e-031.00e+008.907111
GO:2000536negative regulation of entry of bacterium into host cell2.08e-031.00e+008.907111
GO:0002368B cell cytokine production2.08e-031.00e+008.907111
GO:0042277peptide binding2.40e-031.00e+004.7782235
GO:0006413translational initiation2.52e-031.00e+003.459312131
GO:0050681androgen receptor binding2.83e-031.00e+004.6592438
GO:0022627cytosolic small ribosomal subunit2.97e-031.00e+004.6222339
GO:0016887ATPase activity3.29e-031.00e+003.32237144
GO:0006200ATP catabolic process3.48e-031.00e+002.664414303
GO:0045727positive regulation of translation4.12e-031.00e+004.3832446
GO:0034683integrin alphav-beta3 complex4.16e-031.00e+007.907112
GO:0045252oxoglutarate dehydrogenase complex4.16e-031.00e+007.907122
GO:0034686integrin alphav-beta8 complex4.16e-031.00e+007.907112
GO:0002176male germ cell proliferation4.16e-031.00e+007.907112
GO:0006407rRNA export from nucleus4.16e-031.00e+007.907112
GO:0046294formaldehyde catabolic process4.16e-031.00e+007.907112
GO:0042824MHC class I peptide loading complex4.16e-031.00e+007.907112
GO:0001846opsonin binding4.16e-031.00e+007.907112
GO:1990430extracellular matrix protein binding4.16e-031.00e+007.907112
GO:0061034olfactory bulb mitral cell layer development4.16e-031.00e+007.907112
GO:0033144negative regulation of intracellular steroid hormone receptor signaling pathway4.16e-031.00e+007.907112
GO:0050748negative regulation of lipoprotein metabolic process4.16e-031.00e+007.907112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.16e-031.00e+007.907112
GO:0019322pentose biosynthetic process4.16e-031.00e+007.907112
GO:0005055laminin receptor activity4.16e-031.00e+007.907112
GO:0034684integrin alphav-beta5 complex4.16e-031.00e+007.907112
GO:0007127meiosis I4.16e-031.00e+007.907112
GO:0070409carbamoyl phosphate biosynthetic process4.16e-031.00e+007.907112
GO:0019901protein kinase binding4.23e-031.00e+002.585421320
GO:0001948glycoprotein binding4.85e-031.00e+004.2632350
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.63e-031.00e+004.1522554
GO:0003723RNA binding6.10e-031.00e+002.435419355
GO:0031625ubiquitin protein ligase binding6.14e-031.00e+003.000313180
GO:0018119peptidyl-cysteine S-nitrosylation6.24e-031.00e+007.322113
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity6.24e-031.00e+007.322113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb6.24e-031.00e+007.322113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity6.24e-031.00e+007.322113
GO:0045715negative regulation of low-density lipoprotein particle receptor biosynthetic process6.24e-031.00e+007.322113
GO:0005850eukaryotic translation initiation factor 2 complex6.24e-031.00e+007.322113
GO:1900126negative regulation of hyaluronan biosynthetic process6.24e-031.00e+007.322113
GO:0006458'de novo' protein folding6.24e-031.00e+007.322113
GO:0000056ribosomal small subunit export from nucleus6.24e-031.00e+007.322113
GO:0009051pentose-phosphate shunt, oxidative branch6.24e-031.00e+007.322113
GO:0030135coated vesicle6.24e-031.00e+007.322113
GO:0044205'de novo' UMP biosynthetic process6.24e-031.00e+007.322113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process6.24e-031.00e+007.322113
GO:0071439clathrin complex6.24e-031.00e+007.322113
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.31e-031.00e+006.907114
GO:003068690S preribosome8.31e-031.00e+006.907114
GO:0032051clathrin light chain binding8.31e-031.00e+006.907114
GO:0019788NEDD8 ligase activity8.31e-031.00e+006.907114
GO:0051409response to nitrosative stress8.31e-031.00e+006.907114
GO:0006068ethanol catabolic process8.31e-031.00e+006.907114
GO:0006104succinyl-CoA metabolic process8.31e-031.00e+006.907114
GO:0006543glutamine catabolic process8.31e-031.00e+006.907114
GO:0031467Cul7-RING ubiquitin ligase complex8.31e-031.00e+006.907114
GO:0000055ribosomal large subunit export from nucleus8.31e-031.00e+006.907114
GO:0032369negative regulation of lipid transport8.31e-031.00e+006.907114
GO:0051208sequestering of calcium ion8.31e-031.00e+006.907114
GO:1903077negative regulation of protein localization to plasma membrane8.31e-031.00e+006.907114
GO:2000510positive regulation of dendritic cell chemotaxis8.31e-031.00e+006.907114
GO:0003924GTPase activity8.54e-031.00e+002.82739203
GO:0003697single-stranded DNA binding9.06e-031.00e+003.7982969
GO:0003729mRNA binding1.01e-021.00e+003.7172473
GO:0051414response to cortisol1.04e-021.00e+006.585115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.04e-021.00e+006.585125
GO:0038027apolipoprotein A-I-mediated signaling pathway1.04e-021.00e+006.585115
GO:2000001regulation of DNA damage checkpoint1.04e-021.00e+006.585115
GO:0031461cullin-RING ubiquitin ligase complex1.04e-021.00e+006.585115
GO:0043248proteasome assembly1.04e-021.00e+006.585115
GO:0046696lipopolysaccharide receptor complex1.04e-021.00e+006.585115
GO:0004022alcohol dehydrogenase (NAD) activity1.04e-021.00e+006.585115
GO:0030891VCB complex1.04e-021.00e+006.585125
GO:0000730DNA recombinase assembly1.04e-021.00e+006.585135
GO:0006734NADH metabolic process1.04e-021.00e+006.585115
GO:0030976thiamine pyrophosphate binding1.04e-021.00e+006.585115
GO:0006184GTP catabolic process1.06e-021.00e+002.71139220
GO:0071013catalytic step 2 spliceosome1.17e-021.00e+003.6032779
GO:0019083viral transcription1.23e-021.00e+003.5672881
GO:0003688DNA replication origin binding1.24e-021.00e+006.322116
GO:0030130clathrin coat of trans-Golgi network vesicle1.24e-021.00e+006.322116
GO:0035925mRNA 3'-UTR AU-rich region binding1.24e-021.00e+006.322116
GO:0021860pyramidal neuron development1.24e-021.00e+006.322116
GO:0030118clathrin coat1.24e-021.00e+006.322116
GO:0031466Cul5-RING ubiquitin ligase complex1.24e-021.00e+006.322116
GO:0021695cerebellar cortex development1.24e-021.00e+006.322116
GO:0030957Tat protein binding1.24e-021.00e+006.322146
GO:0046134pyrimidine nucleoside biosynthetic process1.24e-021.00e+006.322116
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex1.24e-021.00e+006.322116
GO:0050764regulation of phagocytosis1.24e-021.00e+006.322116
GO:0040020regulation of meiosis1.24e-021.00e+006.322116
GO:0005681spliceosomal complex1.29e-021.00e+003.5322383
GO:0006415translational termination1.41e-021.00e+003.4642887
GO:0042921glucocorticoid receptor signaling pathway1.45e-021.00e+006.100117
GO:0001849complement component C1q binding1.45e-021.00e+006.100117
GO:0000028ribosomal small subunit assembly1.45e-021.00e+006.100117
GO:0010888negative regulation of lipid storage1.45e-021.00e+006.100127
GO:0031462Cul2-RING ubiquitin ligase complex1.45e-021.00e+006.100127
GO:0030132clathrin coat of coated pit1.45e-021.00e+006.100117
GO:0031994insulin-like growth factor I binding1.45e-021.00e+006.100117
GO:0050821protein stabilization1.54e-021.00e+003.3992291
GO:0042470melanosome1.57e-021.00e+003.38321092
GO:0033018sarcoplasmic reticulum lumen1.65e-021.00e+005.907118
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.65e-021.00e+005.907128
GO:0070688MLL5-L complex1.65e-021.00e+005.907118
GO:0006554lysine catabolic process1.65e-021.00e+005.907128
GO:0045116protein neddylation1.65e-021.00e+005.907128
GO:0051082unfolded protein binding1.67e-021.00e+003.3372695
GO:0044183protein binding involved in protein folding1.86e-021.00e+005.737119
GO:0033690positive regulation of osteoblast proliferation1.86e-021.00e+005.737119
GO:0014075response to amine1.86e-021.00e+005.737119
GO:0003016respiratory system process1.86e-021.00e+005.737119
GO:0008494translation activator activity1.86e-021.00e+005.737119
GO:0006228UTP biosynthetic process1.86e-021.00e+005.737119
GO:0031000response to caffeine1.86e-021.00e+005.737129
GO:0022417protein maturation by protein folding1.86e-021.00e+005.737119
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.98e-021.00e+003.20728104
GO:0043032positive regulation of macrophage activation2.06e-021.00e+005.5851110
GO:0008195phosphatidate phosphatase activity2.06e-021.00e+005.5851110
GO:0006069ethanol oxidation2.06e-021.00e+005.5851110
GO:0051775response to redox state2.06e-021.00e+005.5851110
GO:0051604protein maturation2.06e-021.00e+005.5851110
GO:0021756striatum development2.06e-021.00e+005.5851110
GO:0006098pentose-phosphate shunt2.27e-021.00e+005.4481311
GO:0032727positive regulation of interferon-alpha production2.27e-021.00e+005.4481111
GO:0048387negative regulation of retinoic acid receptor signaling pathway2.27e-021.00e+005.4481111
GO:0010569regulation of double-strand break repair via homologous recombination2.27e-021.00e+005.4481111
GO:0031571mitotic G1 DNA damage checkpoint2.27e-021.00e+005.4481311
GO:0045120pronucleus2.27e-021.00e+005.4481111
GO:2000036regulation of stem cell maintenance2.27e-021.00e+005.4481211
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.35e-021.00e+003.074210114
GO:0030529ribonucleoprotein complex2.35e-021.00e+003.07428114
GO:0048255mRNA stabilization2.47e-021.00e+005.3221112
GO:0021794thalamus development2.47e-021.00e+005.3221112
GO:0010745negative regulation of macrophage derived foam cell differentiation2.68e-021.00e+005.2071213
GO:0006646phosphatidylethanolamine biosynthetic process2.68e-021.00e+005.2071213
GO:0005662DNA replication factor A complex2.68e-021.00e+005.2071313
GO:0001530lipopolysaccharide binding2.68e-021.00e+005.2071213
GO:0008266poly(U) RNA binding2.68e-021.00e+005.2071113
GO:0051131chaperone-mediated protein complex assembly2.68e-021.00e+005.2071113
GO:0035267NuA4 histone acetyltransferase complex2.88e-021.00e+005.1001414
GO:0005504fatty acid binding2.88e-021.00e+005.1001114
GO:0043277apoptotic cell clearance2.88e-021.00e+005.1001114
GO:0071285cellular response to lithium ion2.88e-021.00e+005.1001214
GO:0005525GTP binding3.04e-021.00e+002.134311328
GO:0042026protein refolding3.08e-021.00e+005.0001215
GO:0009615response to virus3.08e-021.00e+002.86326132
GO:0017091AU-rich element binding3.08e-021.00e+005.0001115
GO:0050431transforming growth factor beta binding3.08e-021.00e+005.0001115
GO:0000790nuclear chromatin3.12e-021.00e+002.85227133
GO:0042562hormone binding3.28e-021.00e+004.9071116
GO:0071682endocytic vesicle lumen3.28e-021.00e+004.9071116
GO:0050998nitric-oxide synthase binding3.28e-021.00e+004.9071116
GO:00061032-oxoglutarate metabolic process3.28e-021.00e+004.9071116
GO:0031589cell-substrate adhesion3.28e-021.00e+004.9071116
GO:0003735structural constituent of ribosome3.47e-021.00e+002.76728141
GO:0031527filopodium membrane3.48e-021.00e+004.8201117
GO:0010243response to organonitrogen compound3.48e-021.00e+004.8201217
GO:0050919negative chemotaxis3.48e-021.00e+004.8201117
GO:0003746translation elongation factor activity3.48e-021.00e+004.8201317
GO:0031528microvillus membrane3.48e-021.00e+004.8201117
GO:0031258lamellipodium membrane3.48e-021.00e+004.8201217
GO:0045777positive regulation of blood pressure3.48e-021.00e+004.8201117
GO:0075733intracellular transport of virus3.48e-021.00e+004.8201217
GO:0050870positive regulation of T cell activation3.48e-021.00e+004.8201117
GO:0046718viral entry into host cell3.69e-021.00e+004.7371118
GO:0017025TBP-class protein binding3.69e-021.00e+004.7371218
GO:0006541glutamine metabolic process3.69e-021.00e+004.7371118
GO:0035861site of double-strand break3.69e-021.00e+004.7371118
GO:0070371ERK1 and ERK2 cascade3.69e-021.00e+004.7371118
GO:0004004ATP-dependent RNA helicase activity3.69e-021.00e+004.7371218
GO:0061024membrane organization3.70e-021.00e+002.71725146
GO:0010628positive regulation of gene expression3.84e-021.00e+002.68824149
GO:0006457protein folding3.84e-021.00e+002.68828149
GO:0006259DNA metabolic process3.89e-021.00e+004.6591319
GO:0050840extracellular matrix binding3.89e-021.00e+004.6591119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process3.89e-021.00e+004.6591119
GO:0048863stem cell differentiation3.89e-021.00e+004.6591119
GO:0032733positive regulation of interleukin-10 production3.89e-021.00e+004.6591119
GO:0055007cardiac muscle cell differentiation3.89e-021.00e+004.6591119
GO:0034113heterotypic cell-cell adhesion3.89e-021.00e+004.6591119
GO:0030866cortical actin cytoskeleton organization3.89e-021.00e+004.6591119
GO:0090398cellular senescence4.09e-021.00e+004.5851120
GO:0006298mismatch repair4.09e-021.00e+004.5851620
GO:0046777protein autophosphorylation4.27e-021.00e+002.60323158
GO:0000718nucleotide-excision repair, DNA damage removal4.29e-021.00e+004.5151521
GO:0071364cellular response to epidermal growth factor stimulus4.29e-021.00e+004.5151121
GO:0005790smooth endoplasmic reticulum4.49e-021.00e+004.4481122
GO:0006297nucleotide-excision repair, DNA gap filling4.49e-021.00e+004.4481522
GO:0006656phosphatidylcholine biosynthetic process4.49e-021.00e+004.4481322
GO:0032201telomere maintenance via semi-conservative replication4.49e-021.00e+004.4481722
GO:0030863cortical cytoskeleton4.49e-021.00e+004.4481122
GO:0036464cytoplasmic ribonucleoprotein granule4.49e-021.00e+004.4481422
GO:0007052mitotic spindle organization4.49e-021.00e+004.4481222
GO:0000398mRNA splicing, via spliceosome4.61e-021.00e+002.541212165
GO:1900026positive regulation of substrate adhesion-dependent cell spreading4.69e-021.00e+004.3831223
GO:0031463Cul3-RING ubiquitin ligase complex4.69e-021.00e+004.3831223
GO:0043236laminin binding4.69e-021.00e+004.3831123
GO:0006513protein monoubiquitination4.69e-021.00e+004.3831123
GO:0045787positive regulation of cell cycle4.69e-021.00e+004.3831123
GO:0008305integrin complex4.69e-021.00e+004.3831123
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding4.77e-021.00e+002.51525168
GO:0008135translation factor activity, nucleic acid binding4.89e-021.00e+004.3221424
GO:0050766positive regulation of phagocytosis4.89e-021.00e+004.3221124
GO:0006206pyrimidine nucleobase metabolic process4.89e-021.00e+004.3221224
GO:0042100B cell proliferation5.08e-021.00e+004.2631125
GO:0001968fibronectin binding5.08e-021.00e+004.2631125
GO:0042113B cell activation5.08e-021.00e+004.2631225
GO:0017144drug metabolic process5.08e-021.00e+004.2631125
GO:0032735positive regulation of interleukin-12 production5.08e-021.00e+004.2631125
GO:0000722telomere maintenance via recombination5.28e-021.00e+004.2071726
GO:0035987endodermal cell differentiation5.28e-021.00e+004.2071126
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia5.28e-021.00e+004.2071226
GO:0030148sphingolipid biosynthetic process5.28e-021.00e+004.2071126
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane5.28e-021.00e+004.2071126
GO:0019843rRNA binding5.48e-021.00e+004.1521327
GO:0009897external side of plasma membrane5.55e-021.00e+002.39124183
GO:0043022ribosome binding5.68e-021.00e+004.1001328
GO:0019894kinesin binding5.68e-021.00e+004.1001128
GO:0009986cell surface5.69e-021.00e+001.77139422
GO:0005524ATP binding5.84e-021.00e+001.0896461354
GO:0006099tricarboxylic acid cycle5.87e-021.00e+004.0491329
GO:0019005SCF ubiquitin ligase complex5.87e-021.00e+004.0491129
GO:0030669clathrin-coated endocytic vesicle membrane5.87e-021.00e+004.0491129
GO:0001618virus receptor activity6.07e-021.00e+004.0001130
GO:0034504protein localization to nucleus6.07e-021.00e+004.0001230
GO:0042254ribosome biogenesis6.07e-021.00e+004.0001130
GO:0031623receptor internalization6.27e-021.00e+003.9531131
GO:0006271DNA strand elongation involved in DNA replication6.27e-021.00e+003.9531931
GO:0061077chaperone-mediated protein folding6.27e-021.00e+003.9531231
GO:0050661NADP binding6.46e-021.00e+003.9071132
GO:0051219phosphoprotein binding6.46e-021.00e+003.9071332
GO:0033572transferrin transport6.46e-021.00e+003.9071632
GO:0031072heat shock protein binding6.66e-021.00e+003.8631233
GO:0045335phagocytic vesicle6.66e-021.00e+003.8631233
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand7.05e-021.00e+003.7781235
GO:2001237negative regulation of extrinsic apoptotic signaling pathway7.05e-021.00e+003.7781135
GO:0032588trans-Golgi network membrane7.24e-021.00e+003.7371136
GO:0034332adherens junction organization7.24e-021.00e+003.7371136
GO:0034446substrate adhesion-dependent cell spreading7.24e-021.00e+003.7371236
GO:0001895retina homeostasis7.24e-021.00e+003.7371136
GO:0032755positive regulation of interleukin-6 production7.24e-021.00e+003.7371236
GO:0005245voltage-gated calcium channel activity7.43e-021.00e+003.6981137
GO:0051084'de novo' posttranslational protein folding7.43e-021.00e+003.6981437
GO:0018107peptidyl-threonine phosphorylation7.43e-021.00e+003.6981137
GO:0045740positive regulation of DNA replication7.63e-021.00e+003.6591238
GO:0070527platelet aggregation7.63e-021.00e+003.6591238
GO:0021766hippocampus development7.82e-021.00e+003.6221439
GO:0006284base-excision repair7.82e-021.00e+003.6221739
GO:0006096glycolytic process7.82e-021.00e+003.6221439
GO:0032729positive regulation of interferon-gamma production7.82e-021.00e+003.6221239
GO:0032092positive regulation of protein binding7.82e-021.00e+003.6221339
GO:0007595lactation7.82e-021.00e+003.6221239
GO:0000781chromosome, telomeric region8.01e-021.00e+003.5851240
GO:0045785positive regulation of cell adhesion8.20e-021.00e+003.5491541
GO:0043195terminal bouton8.20e-021.00e+003.5491141
GO:0017148negative regulation of translation8.20e-021.00e+003.5491141
GO:0030521androgen receptor signaling pathway8.20e-021.00e+003.5491241
GO:0007067mitotic nuclear division8.33e-021.00e+002.055213231
GO:0008380RNA splicing8.39e-021.00e+002.049213232
GO:0005759mitochondrial matrix8.45e-021.00e+002.043212233
GO:0042110T cell activation8.59e-021.00e+003.4811343
GO:0014070response to organic cyclic compound8.59e-021.00e+003.4811343
GO:0007286spermatid development8.78e-021.00e+003.4481144
GO:0006892post-Golgi vesicle-mediated transport8.78e-021.00e+003.4481244
GO:0005080protein kinase C binding8.78e-021.00e+003.4481144
GO:0015030Cajal body8.97e-021.00e+003.4151245
GO:0006631fatty acid metabolic process8.97e-021.00e+003.4151145
GO:0021762substantia nigra development9.16e-021.00e+003.3831146
GO:0030136clathrin-coated vesicle9.16e-021.00e+003.3831146
GO:0045665negative regulation of neuron differentiation9.16e-021.00e+003.3831246
GO:0006283transcription-coupled nucleotide-excision repair9.16e-021.00e+003.3831846
GO:0019003GDP binding9.54e-021.00e+003.3221248
GO:0003743translation initiation factor activity9.73e-021.00e+003.2921449
GO:0031100organ regeneration9.92e-021.00e+003.2631450
GO:0001523retinoid metabolic process9.92e-021.00e+003.2631250
GO:0016049cell growth9.92e-021.00e+003.2631150
GO:0035690cellular response to drug9.92e-021.00e+003.2631250
GO:0006091generation of precursor metabolites and energy1.01e-011.00e+003.2351351
GO:0006986response to unfolded protein1.01e-011.00e+003.2351251
GO:0005905coated pit1.01e-011.00e+003.2351251
GO:0001669acrosomal vesicle1.01e-011.00e+003.2351151
GO:0003684damaged DNA binding1.01e-011.00e+003.23511151
GO:0006281DNA repair1.04e-011.00e+001.863222264
GO:0002039p53 binding1.09e-011.00e+003.1261755
GO:0000932cytoplasmic mRNA processing body1.10e-011.00e+003.1001356
GO:0000166nucleotide binding1.10e-011.00e+001.82026272
GO:0000724double-strand break repair via homologous recombination1.12e-011.00e+003.0741657
GO:0002244hematopoietic progenitor cell differentiation1.14e-011.00e+003.0491158
GO:0005840ribosome1.16e-011.00e+003.0241259
GO:0045216cell-cell junction organization1.16e-011.00e+003.0241259
GO:0000723telomere maintenance1.16e-011.00e+003.0241859
GO:0005643nuclear pore1.16e-011.00e+003.0241459
GO:0031966mitochondrial membrane1.16e-011.00e+003.0241159
GO:0006302double-strand break repair1.21e-011.00e+002.9531862
GO:0006987activation of signaling protein activity involved in unfolded protein response1.21e-011.00e+002.9531262
GO:0019899enzyme binding1.21e-011.00e+001.737211288
GO:0019903protein phosphatase binding1.23e-011.00e+002.9301463
GO:0042995cell projection1.23e-011.00e+002.9301663
GO:0030141secretory granule1.31e-011.00e+002.8411267
GO:0006665sphingolipid metabolic process1.32e-011.00e+002.8201268
GO:0009055electron carrier activity1.32e-011.00e+002.8201168
GO:0006289nucleotide-excision repair1.34e-011.00e+002.79811269
GO:0034329cell junction assembly1.38e-011.00e+002.7571171
GO:0032587ruffle membrane1.40e-011.00e+002.7371472
GO:0032355response to estradiol1.42e-011.00e+002.7171573
GO:0000785chromatin1.42e-011.00e+002.7171573
GO:0055086nucleobase-containing small molecule metabolic process1.42e-011.00e+002.7171573
GO:0002020protease binding1.43e-011.00e+002.6981474
GO:0006874cellular calcium ion homeostasis1.47e-011.00e+002.6591176
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.47e-011.00e+002.6591376
GO:0046474glycerophospholipid biosynthetic process1.47e-011.00e+002.6591376
GO:0007411axon guidance1.48e-011.00e+001.55429327
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.49e-011.00e+002.6401577
GO:0008584male gonad development1.49e-011.00e+002.6401277
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.49e-011.00e+002.6401677
GO:0007229integrin-mediated signaling pathway1.50e-011.00e+002.6221278
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.54e-011.00e+002.5851280
GO:0007565female pregnancy1.54e-011.00e+002.5851280
GO:0030968endoplasmic reticulum unfolded protein response1.56e-011.00e+002.5671281
GO:0001889liver development1.58e-011.00e+002.5491382
GO:0047485protein N-terminus binding1.65e-011.00e+002.4811486
GO:0006898receptor-mediated endocytosis1.65e-011.00e+002.4811286
GO:0007160cell-matrix adhesion1.68e-011.00e+002.4481388
GO:0018279protein N-linked glycosylation via asparagine1.73e-011.00e+002.3991291
GO:0016363nuclear matrix1.75e-011.00e+002.38311192
GO:0016605PML body1.75e-011.00e+002.3831592
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.75e-011.00e+002.3831492
GO:0006928cellular component movement1.75e-011.00e+002.3831792
GO:0005200structural constituent of cytoskeleton1.77e-011.00e+002.3681793
GO:0016311dephosphorylation1.78e-011.00e+002.3521394
GO:0008270zinc ion binding1.80e-011.00e+000.8484121067
GO:0005178integrin binding1.84e-011.00e+002.3071297
GO:0005737cytoplasm1.85e-011.00e+000.40911983976
GO:0071456cellular response to hypoxia1.85e-011.00e+002.2921498
GO:0007155cell adhesion1.90e-011.00e+001.32228384
GO:0008284positive regulation of cell proliferation1.96e-011.00e+001.29228392
GO:0070588calcium ion transmembrane transport1.99e-011.00e+002.17911106
GO:0014069postsynaptic density1.99e-011.00e+002.17911106
GO:0050900leukocyte migration2.07e-011.00e+002.11311111
GO:0015630microtubule cytoskeleton2.09e-011.00e+002.10015112
GO:0005819spindle2.12e-011.00e+002.07417114
GO:0072562blood microparticle2.16e-011.00e+002.04914116
GO:0044237cellular metabolic process2.19e-011.00e+002.02413118
GO:0032496response to lipopolysaccharide2.25e-011.00e+001.97614122
GO:0006325chromatin organization2.27e-011.00e+001.96414123
GO:0007568aging2.27e-011.00e+001.96413123
GO:0007219Notch signaling pathway2.30e-011.00e+001.94114125
GO:0006260DNA replication2.30e-011.00e+001.941112125
GO:0007050cell cycle arrest2.32e-011.00e+001.93017126
GO:0005506iron ion binding2.33e-011.00e+001.91813127
GO:0006511ubiquitin-dependent protein catabolic process2.33e-011.00e+001.91815127
GO:0030335positive regulation of cell migration2.38e-011.00e+001.88516130
GO:0016477cell migration2.40e-011.00e+001.87416131
GO:0031982vesicle2.45e-011.00e+001.841110134
GO:0006644phospholipid metabolic process2.49e-011.00e+001.80915137
GO:0007596blood coagulation2.52e-011.00e+001.049214464
GO:0016055Wnt signaling pathway2.56e-011.00e+001.76716141
GO:0007507heart development2.56e-011.00e+001.76715141
GO:0030246carbohydrate binding2.71e-011.00e+001.66911151
GO:0042802identical protein binding2.73e-011.00e+000.967218491
GO:0005788endoplasmic reticulum lumen2.80e-011.00e+001.61211157
GO:0005769early endosome2.82e-011.00e+001.60312158
GO:0005198structural molecule activity2.83e-011.00e+001.59414159
GO:0006397mRNA processing2.98e-011.00e+001.50613169
GO:0030424axon3.03e-011.00e+001.48113172
GO:0006886intracellular protein transport3.04e-011.00e+001.47214173
GO:0000287magnesium ion binding3.06e-011.00e+001.46415174
GO:0016607nuclear speck3.07e-011.00e+001.45614175
GO:0004672protein kinase activity3.11e-011.00e+001.43112178
GO:0019904protein domain specific binding3.16e-011.00e+001.40716181
GO:0043687post-translational protein modification3.16e-011.00e+001.40714181
GO:0005578proteinaceous extracellular matrix3.19e-011.00e+001.39111183
GO:0032403protein complex binding3.22e-011.00e+001.37617185
GO:0001525angiogenesis3.43e-011.00e+001.26314200
GO:0005615extracellular space3.52e-011.00e+000.5123171010
GO:0001701in utero embryonic development3.56e-011.00e+001.19316210
GO:0005739mitochondrion3.73e-011.00e+000.4613241046
GO:0005622intracellular3.78e-011.00e+001.08715226
GO:0003713transcription coactivator activity3.95e-011.00e+001.006110239
GO:0043025neuronal cell body4.14e-011.00e+000.91814254
GO:0004842ubiquitin-protein transferase activity4.16e-011.00e+000.90714256
GO:0005975carbohydrate metabolic process4.38e-011.00e+000.80915274
GO:0043065positive regulation of apoptotic process4.38e-011.00e+000.80918274
GO:0007283spermatogenesis4.40e-011.00e+000.79816276
GO:0042493response to drug4.54e-011.00e+000.737111288
GO:0007264small GTPase mediated signal transduction4.57e-011.00e+000.72713290
GO:0030198extracellular matrix organization4.62e-011.00e+000.70213295
GO:0016567protein ubiquitination4.67e-011.00e+000.68315299
GO:0005743mitochondrial inner membrane4.68e-011.00e+000.67815300
GO:0005856cytoskeleton4.80e-011.00e+000.62618311
GO:0004674protein serine/threonine kinase activity4.82e-011.00e+000.62216312
GO:0003682chromatin binding5.05e-011.00e+000.523112334
GO:0005813centrosome5.11e-011.00e+000.502112339
GO:0007275multicellular organismal development5.16e-011.00e+000.48115344
GO:0006508proteolysis5.79e-011.00e+000.22719410
GO:0045892negative regulation of transcription, DNA-templated5.92e-011.00e+000.179114424
GO:0007165signal transduction5.97e-011.00e+000.015217950
GO:0046872metal ion binding5.99e-011.00e+00-0.0253241465
GO:0006468protein phosphorylation6.28e-011.00e+000.040110467
GO:0055114oxidation-reduction process6.39e-011.00e+00-0.003111481
GO:0045893positive regulation of transcription, DNA-templated6.43e-011.00e+00-0.021117487
GO:0048471perinuclear region of cytoplasm6.70e-011.00e+00-0.124112523
GO:0005509calcium ion binding7.14e-011.00e+00-0.29518589
GO:0000122negative regulation of transcription from RNA polymerase II promoter7.14e-011.00e+00-0.295112589
GO:0005783endoplasmic reticulum7.26e-011.00e+00-0.34619610
GO:0045087innate immune response7.30e-011.00e+00-0.360120616
GO:0042803protein homodimerization activity7.31e-011.00e+00-0.362111617
GO:0005789endoplasmic reticulum membrane7.41e-011.00e+00-0.406110636
GO:0005794Golgi apparatus7.49e-011.00e+00-0.437114650
GO:0005886plasma membrane8.65e-011.00e+00-0.5624382834
GO:0005887integral component of plasma membrane8.73e-011.00e+00-1.00117961
GO:0005576extracellular region8.96e-011.00e+00-1.128191049
GO:0006355regulation of transcription, DNA-templated9.08e-011.00e+00-1.2021171104
GO:0003677DNA binding9.47e-011.00e+00-1.4931261351