meta-int-snw-6610

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-56655	wolf-screen-ratio-mammosphere-adherent	0.828	9.29e-07	2.91e-03	5.53e-03	8	7
int-snw-6610	wolf-screen-ratio-mammosphere-adherent	0.974	4.78e-17	1.03e-03	2.11e-02	10	8
reg-snw-5925	wolf-screen-ratio-mammosphere-adherent	0.802	2.42e-06	4.82e-03	8.69e-03	8	5

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-6610 subnetwork

Genes (20)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PPCS	79717	31	-0.569	0.802	2	-	Yes
PSMA2	5683	112	1.093	1.106	108	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
PPIE	10450	31	0.567	0.802	41	-	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
OGDH	4967	72	0.847	0.802	126	Yes	-
POLE4	56655	63	0.177	0.828	56	-	-
TFRC	7037	31	0.730	0.802	17	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
PSMB3	5691	64	0.668	0.901	19	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
RPA2	6118	96	1.250	1.151	76	Yes	-
RB1	5925	31	-0.102	0.802	351	-	-
PCNA	5111	33	0.553	0.974	294	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
SEC22B	9554	5	0.560	0.974	143	-	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
SMPD2	6610	3	0.321	0.974	60	-	-

Interactions (44)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RB1	5925	PPCS	79717	pd	>	reg.pazar.txt: no annot
RB1	5925	RPA2	6118	pd	>	reg.pazar.txt: no annot
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB2	5690	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
PGD	5226	RB1	5925	pd	<	reg.pazar.txt: no annot
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
RBX1	9978	PPIE	10450	pd	<>	reg.ITFP.txt: no annot
RPSA	3921	VARS	7407	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
OGDH	4967	RB1	5925	pd	<	reg.ITFP.txt: no annot
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
VARS	7407	POLE4	56655	pd	<>	reg.ITFP.txt: no annot
ACTB	60	SEC22B	9554	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	POLE4	56655	pd	<	reg.ITFP.txt: no annot
ACTB	60	SMPD2	6610	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PCNA	5111	SEC22B	9554	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMB3	5691	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
OGDH	4967	PSMD11	5717	pp	--	int.I2D: YeastLow
RPSA	3921	PCNA	5111	pp	--	int.I2D: MINT, BioGrid; int.Mint: MI:0915(physical association)
PSMB3	5691	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	PPIE	10450	pd	<	reg.ITFP.txt: no annot
RB1	5925	TFRC	7037	pd	>	reg.ITFP.txt: no annot
SMPD2	6610	SEC22B	9554	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	SMPD2	6610	pp	--	int.I2D: BioGrid_Yeast
PSMB3	5691	PSMD11	5717	pp	--	int.I2D: YeastLow
RB1	5925	PPIE	10450	pd	>	reg.pazar.txt: no annot
PCNA	5111	SMPD2	6610	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (325)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000082	G1/S transition of mitotic cell cycle	4.84e-12	7.90e-08	5.444	8	33	150
GO:0006521	regulation of cellular amino acid metabolic process	3.29e-09	5.37e-05	6.351	5	21	50
GO:0005839	proteasome core complex	4.96e-09	8.10e-05	7.503	4	11	18
GO:0016032	viral process	5.40e-09	8.81e-05	3.766	9	55	540
GO:0000502	proteasome complex	7.07e-09	1.15e-04	6.136	5	22	58
GO:0004298	threonine-type endopeptidase activity	7.84e-09	1.28e-04	7.351	4	11	20
GO:0000278	mitotic cell cycle	1.14e-08	1.85e-04	4.036	8	52	398
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.27e-08	2.07e-04	5.972	5	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.27e-08	2.07e-04	5.972	5	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.85e-08	3.02e-04	5.865	5	24	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.29e-08	3.74e-04	5.805	5	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.46e-08	4.01e-04	5.785	5	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.01e-08	4.91e-04	5.728	5	23	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.42e-08	5.59e-04	5.691	5	25	79
GO:0034641	cellular nitrogen compound metabolic process	5.11e-08	8.33e-04	4.790	6	25	177
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	8.24e-08	1.35e-03	5.440	5	23	94
GO:0005654	nucleoplasm	1.76e-07	2.88e-03	2.898	10	83	1095
GO:0016071	mRNA metabolic process	2.01e-07	3.28e-03	4.457	6	34	223
GO:0000209	protein polyubiquitination	2.37e-07	3.86e-03	5.136	5	21	116
GO:0016070	RNA metabolic process	3.67e-07	5.99e-03	4.309	6	34	247
GO:0042981	regulation of apoptotic process	8.79e-07	1.44e-02	4.756	5	26	151
GO:0044281	small molecule metabolic process	9.11e-06	1.49e-01	2.504	9	57	1295
GO:0010467	gene expression	9.15e-06	1.49e-01	3.094	7	58	669
GO:0070062	extracellular vesicular exosome	4.95e-05	8.08e-01	1.835	11	98	2516
GO:0005829	cytosol	5.88e-05	9.60e-01	1.809	11	125	2562
GO:0043066	negative regulation of apoptotic process	1.43e-04	1.00e+00	3.236	5	30	433
GO:0006298	mismatch repair	2.67e-04	1.00e+00	6.351	2	6	20
GO:0006297	nucleotide-excision repair, DNA gap filling	3.25e-04	1.00e+00	6.213	2	5	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	3.25e-04	1.00e+00	6.213	2	3	22
GO:0032201	telomere maintenance via semi-conservative replication	3.25e-04	1.00e+00	6.213	2	7	22
GO:0000722	telomere maintenance via recombination	4.56e-04	1.00e+00	5.972	2	7	26
GO:0006915	apoptotic process	5.16e-04	1.00e+00	2.837	5	34	571
GO:0006271	DNA strand elongation involved in DNA replication	6.49e-04	1.00e+00	5.718	2	9	31
GO:0005515	protein binding	7.38e-04	1.00e+00	0.998	15	172	6127
GO:0006284	base-excision repair	1.03e-03	1.00e+00	5.387	2	7	39
GO:0032077	positive regulation of deoxyribonuclease activity	1.23e-03	1.00e+00	9.673	1	1	1
GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity	1.23e-03	1.00e+00	9.673	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	1.23e-03	1.00e+00	9.673	1	1	1
GO:0043626	PCNA complex	1.23e-03	1.00e+00	9.673	1	1	1
GO:0090230	regulation of centromere complex assembly	1.23e-03	1.00e+00	9.673	1	1	1
GO:0004632	phosphopantothenate--cysteine ligase activity	1.23e-03	1.00e+00	9.673	1	1	1
GO:0019521	D-gluconate metabolic process	1.23e-03	1.00e+00	9.673	1	1	1
GO:0031625	ubiquitin protein ligase binding	1.31e-03	1.00e+00	3.766	3	13	180
GO:0006283	transcription-coupled nucleotide-excision repair	1.43e-03	1.00e+00	5.149	2	8	46
GO:0000723	telomere maintenance	2.34e-03	1.00e+00	4.790	2	8	59
GO:0004832	valine-tRNA ligase activity	2.45e-03	1.00e+00	8.673	1	1	2
GO:0030337	DNA polymerase processivity factor activity	2.45e-03	1.00e+00	8.673	1	1	2
GO:0006272	leading strand elongation	2.45e-03	1.00e+00	8.673	1	2	2
GO:0045252	oxoglutarate dehydrogenase complex	2.45e-03	1.00e+00	8.673	1	2	2
GO:0097286	iron ion import	2.45e-03	1.00e+00	8.673	1	1	2
GO:0006407	rRNA export from nucleus	2.45e-03	1.00e+00	8.673	1	1	2
GO:0006438	valyl-tRNA aminoacylation	2.45e-03	1.00e+00	8.673	1	1	2
GO:0070557	PCNA-p21 complex	2.45e-03	1.00e+00	8.673	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	2.45e-03	1.00e+00	8.673	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.45e-03	1.00e+00	8.673	1	1	2
GO:0004998	transferrin receptor activity	2.45e-03	1.00e+00	8.673	1	1	2
GO:0019322	pentose biosynthetic process	2.45e-03	1.00e+00	8.673	1	1	2
GO:0031134	sister chromatid biorientation	2.45e-03	1.00e+00	8.673	1	1	2
GO:0005055	laminin receptor activity	2.45e-03	1.00e+00	8.673	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	2.45e-03	1.00e+00	8.673	1	2	2
GO:0006289	nucleotide-excision repair	3.19e-03	1.00e+00	4.564	2	12	69
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	3.67e-03	1.00e+00	8.088	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	3.67e-03	1.00e+00	8.088	1	1	3
GO:0032139	dinucleotide insertion or deletion binding	3.67e-03	1.00e+00	8.088	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	3.67e-03	1.00e+00	8.088	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	3.67e-03	1.00e+00	8.088	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	3.67e-03	1.00e+00	8.088	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	3.67e-03	1.00e+00	8.088	1	1	3
GO:0006281	DNA repair	3.89e-03	1.00e+00	3.213	3	22	264
GO:0005634	nucleus	4.50e-03	1.00e+00	1.020	12	131	4828
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.89e-03	1.00e+00	7.673	1	1	4
GO:0030686	90S preribosome	4.89e-03	1.00e+00	7.673	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	4.89e-03	1.00e+00	7.673	1	1	4
GO:0006684	sphingomyelin metabolic process	4.89e-03	1.00e+00	7.673	1	1	4
GO:0019788	NEDD8 ligase activity	4.89e-03	1.00e+00	7.673	1	1	4
GO:0006104	succinyl-CoA metabolic process	4.89e-03	1.00e+00	7.673	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	4.89e-03	1.00e+00	7.673	1	1	4
GO:0043550	regulation of lipid kinase activity	4.89e-03	1.00e+00	7.673	1	1	4
GO:0035189	Rb-E2F complex	4.89e-03	1.00e+00	7.673	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	4.89e-03	1.00e+00	7.673	1	1	4
GO:0034349	glial cell apoptotic process	4.89e-03	1.00e+00	7.673	1	1	4
GO:0016605	PML body	5.59e-03	1.00e+00	4.149	2	5	92
GO:0042470	melanosome	5.59e-03	1.00e+00	4.149	2	10	92
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	6.11e-03	1.00e+00	7.351	1	2	5
GO:2000001	regulation of DNA damage checkpoint	6.11e-03	1.00e+00	7.351	1	1	5
GO:0008622	epsilon DNA polymerase complex	6.11e-03	1.00e+00	7.351	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	6.11e-03	1.00e+00	7.351	1	1	5
GO:0043248	proteasome assembly	6.11e-03	1.00e+00	7.351	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	6.11e-03	1.00e+00	7.351	1	1	5
GO:0030891	VCB complex	6.11e-03	1.00e+00	7.351	1	2	5
GO:0000730	DNA recombinase assembly	6.11e-03	1.00e+00	7.351	1	3	5
GO:0006734	NADH metabolic process	6.11e-03	1.00e+00	7.351	1	1	5
GO:0030976	thiamine pyrophosphate binding	6.11e-03	1.00e+00	7.351	1	1	5
GO:0043353	enucleate erythrocyte differentiation	7.33e-03	1.00e+00	7.088	1	1	6
GO:0009108	coenzyme biosynthetic process	7.33e-03	1.00e+00	7.088	1	1	6
GO:0005663	DNA replication factor C complex	7.33e-03	1.00e+00	7.088	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	7.33e-03	1.00e+00	7.088	1	1	6
GO:0021860	pyramidal neuron development	7.33e-03	1.00e+00	7.088	1	1	6
GO:0033993	response to lipid	7.33e-03	1.00e+00	7.088	1	2	6
GO:0031466	Cul5-RING ubiquitin ligase complex	7.33e-03	1.00e+00	7.088	1	1	6
GO:0021695	cerebellar cortex development	7.33e-03	1.00e+00	7.088	1	1	6
GO:0030957	Tat protein binding	7.33e-03	1.00e+00	7.088	1	4	6
GO:0032405	MutLalpha complex binding	7.33e-03	1.00e+00	7.088	1	2	6
GO:0000028	ribosomal small subunit assembly	8.55e-03	1.00e+00	6.865	1	1	7
GO:0002161	aminoacyl-tRNA editing activity	8.55e-03	1.00e+00	6.865	1	2	7
GO:0004767	sphingomyelin phosphodiesterase activity	8.55e-03	1.00e+00	6.865	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	8.55e-03	1.00e+00	6.865	1	2	7
GO:0016018	cyclosporin A binding	8.55e-03	1.00e+00	6.865	1	1	7
GO:0072562	blood microparticle	8.75e-03	1.00e+00	3.815	2	4	116
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	9.76e-03	1.00e+00	6.673	1	2	8
GO:0070688	MLL5-L complex	9.76e-03	1.00e+00	6.673	1	1	8
GO:0006554	lysine catabolic process	9.76e-03	1.00e+00	6.673	1	2	8
GO:0070182	DNA polymerase binding	9.76e-03	1.00e+00	6.673	1	2	8
GO:0045116	protein neddylation	9.76e-03	1.00e+00	6.673	1	2	8
GO:0019773	proteasome core complex, alpha-subunit complex	9.76e-03	1.00e+00	6.673	1	5	8
GO:0043596	nuclear replication fork	9.76e-03	1.00e+00	6.673	1	1	8
GO:0015937	coenzyme A biosynthetic process	1.10e-02	1.00e+00	6.503	1	1	9
GO:0097284	hepatocyte apoptotic process	1.10e-02	1.00e+00	6.503	1	2	9
GO:0000075	cell cycle checkpoint	1.10e-02	1.00e+00	6.503	1	2	9
GO:0006450	regulation of translational fidelity	1.22e-02	1.00e+00	6.351	1	2	10
GO:0015939	pantothenate metabolic process	1.22e-02	1.00e+00	6.351	1	1	10
GO:0021756	striatum development	1.22e-02	1.00e+00	6.351	1	1	10
GO:0006098	pentose-phosphate shunt	1.34e-02	1.00e+00	6.213	1	3	11
GO:0010569	regulation of double-strand break repair via homologous recombination	1.34e-02	1.00e+00	6.213	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.34e-02	1.00e+00	6.213	1	3	11
GO:0042551	neuron maturation	1.34e-02	1.00e+00	6.213	1	2	11
GO:0045651	positive regulation of macrophage differentiation	1.34e-02	1.00e+00	6.213	1	2	11
GO:0006457	protein folding	1.41e-02	1.00e+00	3.453	2	8	149
GO:0019985	translesion synthesis	1.46e-02	1.00e+00	6.088	1	2	12
GO:0051146	striated muscle cell differentiation	1.46e-02	1.00e+00	6.088	1	1	12
GO:0006275	regulation of DNA replication	1.46e-02	1.00e+00	6.088	1	2	12
GO:0021794	thalamus development	1.46e-02	1.00e+00	6.088	1	1	12
GO:0005838	proteasome regulatory particle	1.46e-02	1.00e+00	6.088	1	7	12
GO:0005662	DNA replication factor A complex	1.58e-02	1.00e+00	5.972	1	3	13
GO:0045780	positive regulation of bone resorption	1.58e-02	1.00e+00	5.972	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.70e-02	1.00e+00	5.865	1	4	14
GO:0045445	myoblast differentiation	1.82e-02	1.00e+00	5.766	1	2	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	1.82e-02	1.00e+00	5.766	1	1	15
GO:0016514	SWI/SNF complex	1.82e-02	1.00e+00	5.766	1	3	15
GO:0046513	ceramide biosynthetic process	1.94e-02	1.00e+00	5.673	1	1	16
GO:0050998	nitric-oxide synthase binding	1.94e-02	1.00e+00	5.673	1	1	16
GO:0006103	2-oxoglutarate metabolic process	1.94e-02	1.00e+00	5.673	1	1	16
GO:0010243	response to organonitrogen compound	2.06e-02	1.00e+00	5.585	1	2	17
GO:0045070	positive regulation of viral genome replication	2.06e-02	1.00e+00	5.585	1	1	17
GO:0022624	proteasome accessory complex	2.06e-02	1.00e+00	5.585	1	9	17
GO:0042802	identical protein binding	2.11e-02	1.00e+00	2.318	3	18	491
GO:0035861	site of double-strand break	2.18e-02	1.00e+00	5.503	1	1	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.30e-02	1.00e+00	5.425	1	1	19
GO:0048863	stem cell differentiation	2.30e-02	1.00e+00	5.425	1	1	19
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.42e-02	1.00e+00	5.351	1	2	20
GO:0000718	nucleotide-excision repair, DNA damage removal	2.54e-02	1.00e+00	5.280	1	5	21
GO:0030316	osteoclast differentiation	2.66e-02	1.00e+00	5.213	1	2	22
GO:0046686	response to cadmium ion	2.66e-02	1.00e+00	5.213	1	3	22
GO:0030863	cortical cytoskeleton	2.66e-02	1.00e+00	5.213	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.66e-02	1.00e+00	5.213	1	4	22
GO:0031463	Cul3-RING ubiquitin ligase complex	2.78e-02	1.00e+00	5.149	1	2	23
GO:0043236	laminin binding	2.78e-02	1.00e+00	5.149	1	1	23
GO:0006513	protein monoubiquitination	2.78e-02	1.00e+00	5.149	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	2.78e-02	1.00e+00	5.149	1	4	23
GO:0045879	negative regulation of smoothened signaling pathway	2.78e-02	1.00e+00	5.149	1	1	23
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.14e-02	1.00e+00	4.972	1	2	26
GO:0048565	digestive tract development	3.26e-02	1.00e+00	4.918	1	1	27
GO:0043022	ribosome binding	3.38e-02	1.00e+00	4.865	1	3	28
GO:0031492	nucleosomal DNA binding	3.38e-02	1.00e+00	4.865	1	4	28
GO:0019894	kinesin binding	3.38e-02	1.00e+00	4.865	1	1	28
GO:0006099	tricarboxylic acid cycle	3.50e-02	1.00e+00	4.815	1	3	29
GO:0019005	SCF ubiquitin ligase complex	3.50e-02	1.00e+00	4.815	1	1	29
GO:0003887	DNA-directed DNA polymerase activity	3.50e-02	1.00e+00	4.815	1	3	29
GO:0071897	DNA biosynthetic process	3.50e-02	1.00e+00	4.815	1	2	29
GO:0007346	regulation of mitotic cell cycle	3.61e-02	1.00e+00	4.766	1	3	30
GO:0007093	mitotic cell cycle checkpoint	3.73e-02	1.00e+00	4.718	1	2	31
GO:0050661	NADP binding	3.85e-02	1.00e+00	4.673	1	1	32
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	3.85e-02	1.00e+00	4.673	1	1	32
GO:0051219	phosphoprotein binding	3.85e-02	1.00e+00	4.673	1	3	32
GO:0033572	transferrin transport	3.85e-02	1.00e+00	4.673	1	6	32
GO:0030971	receptor tyrosine kinase binding	3.97e-02	1.00e+00	4.628	1	2	33
GO:0031072	heat shock protein binding	3.97e-02	1.00e+00	4.628	1	2	33
GO:0000413	protein peptidyl-prolyl isomerization	4.09e-02	1.00e+00	4.585	1	1	34
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4.09e-02	1.00e+00	4.585	1	1	34
GO:0034332	adherens junction organization	4.32e-02	1.00e+00	4.503	1	1	36
GO:0051402	neuron apoptotic process	4.32e-02	1.00e+00	4.503	1	2	36
GO:0001895	retina homeostasis	4.32e-02	1.00e+00	4.503	1	1	36
GO:0001102	RNA polymerase II activating transcription factor binding	4.44e-02	1.00e+00	4.463	1	4	37
GO:0051084	'de novo' posttranslational protein folding	4.44e-02	1.00e+00	4.463	1	4	37
GO:0070527	platelet aggregation	4.56e-02	1.00e+00	4.425	1	2	38
GO:0006687	glycosphingolipid metabolic process	4.56e-02	1.00e+00	4.425	1	1	38
GO:0050681	androgen receptor binding	4.56e-02	1.00e+00	4.425	1	4	38
GO:0021766	hippocampus development	4.67e-02	1.00e+00	4.387	1	4	39
GO:0006096	glycolytic process	4.67e-02	1.00e+00	4.387	1	4	39
GO:0022627	cytosolic small ribosomal subunit	4.67e-02	1.00e+00	4.387	1	3	39
GO:0000781	chromosome, telomeric region	4.79e-02	1.00e+00	4.351	1	2	40
GO:0030521	androgen receptor signaling pathway	4.91e-02	1.00e+00	4.315	1	2	41
GO:0006418	tRNA aminoacylation for protein translation	5.03e-02	1.00e+00	4.280	1	5	42
GO:0035914	skeletal muscle cell differentiation	5.03e-02	1.00e+00	4.280	1	1	42
GO:0014070	response to organic cyclic compound	5.14e-02	1.00e+00	4.246	1	3	43
GO:0043966	histone H3 acetylation	5.38e-02	1.00e+00	4.181	1	2	45
GO:0021762	substantia nigra development	5.49e-02	1.00e+00	4.149	1	1	46
GO:0001047	core promoter binding	5.49e-02	1.00e+00	4.149	1	2	46
GO:0016020	membrane	5.51e-02	1.00e+00	1.225	5	80	1746
GO:0006091	generation of precursor metabolites and energy	6.07e-02	1.00e+00	4.000	1	3	51
GO:0005905	coated pit	6.07e-02	1.00e+00	4.000	1	2	51
GO:0003684	damaged DNA binding	6.07e-02	1.00e+00	4.000	1	11	51
GO:0003725	double-stranded RNA binding	6.42e-02	1.00e+00	3.918	1	6	54
GO:0009612	response to mechanical stimulus	6.42e-02	1.00e+00	3.918	1	2	54
GO:0019900	kinase binding	6.42e-02	1.00e+00	3.918	1	1	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	6.42e-02	1.00e+00	3.918	1	5	54
GO:0050680	negative regulation of epithelial cell proliferation	6.42e-02	1.00e+00	3.918	1	1	54
GO:0006888	ER to Golgi vesicle-mediated transport	6.53e-02	1.00e+00	3.891	1	2	55
GO:0000932	cytoplasmic mRNA processing body	6.65e-02	1.00e+00	3.865	1	3	56
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	6.76e-02	1.00e+00	3.840	1	1	57
GO:0006879	cellular iron ion homeostasis	6.76e-02	1.00e+00	3.840	1	5	57
GO:0000724	double-strand break repair via homologous recombination	6.76e-02	1.00e+00	3.840	1	6	57
GO:0051087	chaperone binding	6.99e-02	1.00e+00	3.790	1	6	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	6.99e-02	1.00e+00	3.790	1	4	59
GO:0045216	cell-cell junction organization	6.99e-02	1.00e+00	3.790	1	2	59
GO:0031966	mitochondrial membrane	6.99e-02	1.00e+00	3.790	1	1	59
GO:0006302	double-strand break repair	7.33e-02	1.00e+00	3.718	1	8	62
GO:0005901	caveola	7.45e-02	1.00e+00	3.695	1	3	63
GO:0019903	protein phosphatase binding	7.45e-02	1.00e+00	3.695	1	4	63
GO:0030855	epithelial cell differentiation	7.68e-02	1.00e+00	3.650	1	4	65
GO:0006469	negative regulation of protein kinase activity	7.68e-02	1.00e+00	3.650	1	2	65
GO:0001558	regulation of cell growth	7.79e-02	1.00e+00	3.628	1	4	66
GO:0006665	sphingolipid metabolic process	8.02e-02	1.00e+00	3.585	1	2	68
GO:0006338	chromatin remodeling	8.02e-02	1.00e+00	3.585	1	4	68
GO:0003697	single-stranded DNA binding	8.13e-02	1.00e+00	3.564	1	9	69
GO:0034329	cell junction assembly	8.35e-02	1.00e+00	3.523	1	1	71
GO:0055037	recycling endosome	8.58e-02	1.00e+00	3.483	1	2	73
GO:0000785	chromatin	8.58e-02	1.00e+00	3.483	1	5	73
GO:0006767	water-soluble vitamin metabolic process	8.81e-02	1.00e+00	3.444	1	3	75
GO:0007265	Ras protein signal transduction	8.81e-02	1.00e+00	3.444	1	3	75
GO:0031175	neuron projection development	8.81e-02	1.00e+00	3.444	1	1	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	8.92e-02	1.00e+00	3.425	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	9.03e-02	1.00e+00	3.406	1	5	77
GO:0006766	vitamin metabolic process	9.14e-02	1.00e+00	3.387	1	3	78
GO:0071013	catalytic step 2 spliceosome	9.25e-02	1.00e+00	3.369	1	7	79
GO:0019083	viral transcription	9.48e-02	1.00e+00	3.333	1	8	81
GO:0047485	protein N-terminus binding	1.00e-01	1.00e+00	3.246	1	4	86
GO:0006898	receptor-mediated endocytosis	1.00e-01	1.00e+00	3.246	1	2	86
GO:0006415	translational termination	1.01e-01	1.00e+00	3.230	1	8	87
GO:0006928	cellular component movement	1.07e-01	1.00e+00	3.149	1	7	92
GO:0006414	translational elongation	1.08e-01	1.00e+00	3.133	1	11	93
GO:0005200	structural constituent of cytoskeleton	1.08e-01	1.00e+00	3.133	1	7	93
GO:0071456	cellular response to hypoxia	1.14e-01	1.00e+00	3.058	1	4	98
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.20e-01	1.00e+00	2.972	1	8	104
GO:0014069	postsynaptic density	1.22e-01	1.00e+00	2.945	1	1	106
GO:0044267	cellular protein metabolic process	1.22e-01	1.00e+00	1.721	2	24	495
GO:0016023	cytoplasmic membrane-bounded vesicle	1.23e-01	1.00e+00	2.931	1	3	107
GO:0042127	regulation of cell proliferation	1.28e-01	1.00e+00	2.878	1	4	111
GO:0015630	microtubule cytoskeleton	1.29e-01	1.00e+00	2.865	1	5	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.31e-01	1.00e+00	2.840	1	10	114
GO:0030529	ribonucleoprotein complex	1.31e-01	1.00e+00	2.840	1	8	114
GO:0005819	spindle	1.31e-01	1.00e+00	2.840	1	7	114
GO:0019058	viral life cycle	1.32e-01	1.00e+00	2.827	1	10	115
GO:0097190	apoptotic signaling pathway	1.33e-01	1.00e+00	2.815	1	4	116
GO:0005739	mitochondrion	1.33e-01	1.00e+00	1.227	3	24	1046
GO:0044237	cellular metabolic process	1.35e-01	1.00e+00	2.790	1	3	118
GO:0006325	chromatin organization	1.40e-01	1.00e+00	2.730	1	4	123
GO:0044822	poly(A) RNA binding	1.42e-01	1.00e+00	1.183	3	50	1078
GO:0007219	Notch signaling pathway	1.43e-01	1.00e+00	2.707	1	4	125
GO:0006260	DNA replication	1.43e-01	1.00e+00	2.707	1	12	125
GO:0005730	nucleolus	1.44e-01	1.00e+00	0.955	4	70	1684
GO:0007050	cell cycle arrest	1.44e-01	1.00e+00	2.695	1	7	126
GO:0006511	ubiquitin-dependent protein catabolic process	1.45e-01	1.00e+00	2.684	1	5	127
GO:0006413	translational initiation	1.49e-01	1.00e+00	2.639	1	12	131
GO:0009615	response to virus	1.50e-01	1.00e+00	2.628	1	6	132
GO:0000790	nuclear chromatin	1.51e-01	1.00e+00	2.617	1	7	133
GO:0031982	vesicle	1.52e-01	1.00e+00	2.606	1	10	134
GO:0003735	structural constituent of ribosome	1.59e-01	1.00e+00	2.533	1	8	141
GO:0007507	heart development	1.59e-01	1.00e+00	2.533	1	5	141
GO:0061024	membrane organization	1.65e-01	1.00e+00	2.483	1	5	146
GO:0000398	mRNA splicing, via spliceosome	1.84e-01	1.00e+00	2.306	1	12	165
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.87e-01	1.00e+00	2.280	1	5	168
GO:0005794	Golgi apparatus	1.88e-01	1.00e+00	1.328	2	14	650
GO:0030424	axon	1.91e-01	1.00e+00	2.246	1	3	172
GO:0005768	endosome	1.93e-01	1.00e+00	2.230	1	5	174
GO:0009897	external side of plasma membrane	2.02e-01	1.00e+00	2.157	1	4	183
GO:0015629	actin cytoskeleton	2.02e-01	1.00e+00	2.157	1	5	183
GO:0032403	protein complex binding	2.04e-01	1.00e+00	2.141	1	7	185
GO:0005759	mitochondrial matrix	2.50e-01	1.00e+00	1.808	1	12	233
GO:0006412	translation	2.52e-01	1.00e+00	1.796	1	15	235
GO:0003713	transcription coactivator activity	2.56e-01	1.00e+00	1.772	1	10	239
GO:0008134	transcription factor binding	2.62e-01	1.00e+00	1.730	1	8	246
GO:0004842	ubiquitin-protein transferase activity	2.71e-01	1.00e+00	1.673	1	4	256
GO:0048011	neurotrophin TRK receptor signaling pathway	2.86e-01	1.00e+00	1.580	1	6	273
GO:0000166	nucleotide binding	2.86e-01	1.00e+00	1.585	1	6	272
GO:0005975	carbohydrate metabolic process	2.87e-01	1.00e+00	1.574	1	5	274
GO:0019899	enzyme binding	3.00e-01	1.00e+00	1.503	1	11	288
GO:0016567	protein ubiquitination	3.09e-01	1.00e+00	1.449	1	5	299
GO:0043234	protein complex	3.10e-01	1.00e+00	1.444	1	17	300
GO:0005856	cytoskeleton	3.20e-01	1.00e+00	1.392	1	8	311
GO:0035556	intracellular signal transduction	3.25e-01	1.00e+00	1.364	1	6	317
GO:0019901	protein kinase binding	3.27e-01	1.00e+00	1.351	1	21	320
GO:0005887	integral component of plasma membrane	3.31e-01	1.00e+00	0.764	2	7	961
GO:0007411	axon guidance	3.33e-01	1.00e+00	1.319	1	9	327
GO:0008283	cell proliferation	3.36e-01	1.00e+00	1.302	1	12	331
GO:0043231	intracellular membrane-bounded organelle	3.37e-01	1.00e+00	1.297	1	8	332
GO:0005813	centrosome	3.43e-01	1.00e+00	1.267	1	12	339
GO:0005615	extracellular space	3.54e-01	1.00e+00	0.692	2	17	1010
GO:0003723	RNA binding	3.56e-01	1.00e+00	1.201	1	19	355
GO:0015031	protein transport	3.58e-01	1.00e+00	1.193	1	4	357
GO:0043565	sequence-specific DNA binding	3.64e-01	1.00e+00	1.161	1	4	365
GO:0005925	focal adhesion	3.68e-01	1.00e+00	1.141	1	18	370
GO:0007155	cell adhesion	3.79e-01	1.00e+00	1.088	1	8	384
GO:0046982	protein heterodimerization activity	3.91e-01	1.00e+00	1.032	1	11	399
GO:0009986	cell surface	4.08e-01	1.00e+00	0.951	1	9	422
GO:0045892	negative regulation of transcription, DNA-templated	4.09e-01	1.00e+00	0.945	1	14	424
GO:0007596	blood coagulation	4.39e-01	1.00e+00	0.815	1	14	464
GO:0055114	oxidation-reduction process	4.50e-01	1.00e+00	0.763	1	11	481
GO:0045893	positive regulation of transcription, DNA-templated	4.55e-01	1.00e+00	0.745	1	17	487
GO:0055085	transmembrane transport	4.73e-01	1.00e+00	0.667	1	8	514
GO:0048471	perinuclear region of cytoplasm	4.79e-01	1.00e+00	0.642	1	12	523
GO:0005524	ATP binding	5.03e-01	1.00e+00	0.270	2	46	1354
GO:0045087	innate immune response	5.37e-01	1.00e+00	0.406	1	20	616
GO:0046872	metal ion binding	5.47e-01	1.00e+00	0.156	2	24	1465
GO:0005789	endoplasmic reticulum membrane	5.49e-01	1.00e+00	0.360	1	10	636
GO:0003700	sequence-specific DNA binding transcription factor activity	6.09e-01	1.00e+00	0.126	1	11	748
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.39e-01	1.00e+00	0.009	1	19	811
GO:0005886	plasma membrane	7.00e-01	1.00e+00	-0.211	3	38	2834
GO:0005576	extracellular region	7.35e-01	1.00e+00	-0.362	1	9	1049
GO:0008270	zinc ion binding	7.42e-01	1.00e+00	-0.387	1	12	1067
GO:0006355	regulation of transcription, DNA-templated	7.54e-01	1.00e+00	-0.436	1	17	1104
GO:0005737	cytoplasm	7.55e-01	1.00e+00	-0.285	4	98	3976
GO:0003677	DNA binding	8.23e-01	1.00e+00	-0.727	1	26	1351
GO:0006351	transcription, DNA-templated	8.71e-01	1.00e+00	-0.958	1	25	1585
GO:0016021	integral component of membrane	9.63e-01	1.00e+00	-1.605	1	15	2483

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-6610

Interacting subnets

Genes (20)

Interactions (44)

Related GO terms (325)