meta-int-snw-6309

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-56655	wolf-screen-ratio-mammosphere-adherent	0.828	9.29e-07	2.91e-03	5.53e-03	8	7
int-snw-6309	wolf-screen-ratio-mammosphere-adherent	0.967	9.35e-17	1.22e-03	2.39e-02	11	10
reg-snw-317781	wolf-screen-ratio-mammosphere-adherent	0.823	1.13e-06	3.23e-03	6.07e-03	9	9
reg-snw-5925	wolf-screen-ratio-mammosphere-adherent	0.802	2.42e-06	4.82e-03	8.69e-03	8	5

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-6309 subnetwork

Genes (24)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PPCS	79717	31	-0.569	0.802	2	-	Yes
PSMA2	5683	112	1.093	1.106	108	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
PPIE	10450	31	0.567	0.802	41	-	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
OGDH	4967	72	0.847	0.802	126	Yes	-
DDX51	317781	53	0.059	0.823	210	Yes	-
DLST	1743	22	0.646	1.026	135	Yes	-
POLE4	56655	63	0.177	0.828	56	-	-
TFRC	7037	31	0.730	0.802	17	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
PSMB3	5691	64	0.668	0.901	19	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
ADH5	128	16	0.633	0.994	43	Yes	-
RPA2	6118	96	1.250	1.151	76	Yes	-
EIF6	3692	67	0.700	0.876	316	Yes	-
RB1	5925	31	-0.102	0.802	351	-	-
PSMD3	5709	100	0.986	1.106	201	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
TUBG1	7283	98	0.974	0.973	91	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
SC5D	6309	4	-0.063	0.967	113	-	-

Interactions (62)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RB1	5925	PPCS	79717	pd	>	reg.pazar.txt: no annot
RB1	5925	RPA2	6118	pd	>	reg.pazar.txt: no annot
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB2	5690	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB3	5691	PSMD3	5709	pp	--	int.I2D: YeastLow
DLST	1743	OGDH	4967	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, BioGrid, HPRD, YeastHigh; int.HPRD: in vitro
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
PGD	5226	RB1	5925	pd	<	reg.pazar.txt: no annot
ADH5	128	SC5D	6309	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
RBX1	9978	PPIE	10450	pd	<>	reg.ITFP.txt: no annot
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
EIF6	3692	OGDH	4967	pp	--	int.I2D: YeastLow
RPSA	3921	VARS	7407	pp	--	int.I2D: IntAct_Yeast
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
EIF6	3692	PGD	5226	pp	--	int.I2D: YeastLow
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	SC5D	6309	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
DLST	1743	SC5D	6309	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	RB1	5925	pd	<	reg.ITFP.txt: no annot
DLST	1743	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
VARS	7407	POLE4	56655	pd	<>	reg.ITFP.txt: no annot
PSMA2	5683	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	POLE4	56655	pd	<	reg.ITFP.txt: no annot
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
PSMB7	5695	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMD3	5709	SC5D	6309	pp	--	int.I2D: IntAct_Yeast
PSMB3	5691	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
VARS	7407	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
OGDH	4967	PSMD3	5709	pp	--	int.I2D: YeastLow
PSMB2	5690	DDX51	317781	pd	<	reg.ITFP.txt: no annot
OGDH	4967	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMB3	5691	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	PPIE	10450	pd	<	reg.ITFP.txt: no annot
RB1	5925	TFRC	7037	pd	>	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMB3	5691	PSMD11	5717	pp	--	int.I2D: YeastLow
RB1	5925	PPIE	10450	pd	>	reg.pazar.txt: no annot
EIF6	3692	DDX51	317781	pd	<	reg.ITFP.txt: no annot
EIF6	3692	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (340)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000082	G1/S transition of mitotic cell cycle	2.74e-11	4.47e-07	5.181	8	33	150
GO:0006521	regulation of cellular amino acid metabolic process	7.82e-11	1.28e-06	6.351	6	21	50
GO:0034641	cellular nitrogen compound metabolic process	1.04e-10	1.69e-06	4.942	8	25	177
GO:0000502	proteasome complex	1.98e-10	3.23e-06	6.136	6	22	58
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.01e-10	6.54e-06	5.972	6	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.01e-10	6.54e-06	5.972	6	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.33e-10	1.03e-05	5.865	6	24	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	8.20e-10	1.34e-05	5.805	6	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.91e-10	1.45e-05	5.785	6	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.14e-09	1.86e-05	5.728	6	23	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.33e-09	2.17e-05	5.691	6	25	79
GO:0016032	viral process	1.87e-09	3.05e-05	3.655	10	55	540
GO:0000278	mitotic cell cycle	2.64e-09	4.30e-05	3.943	9	52	398
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.84e-09	6.27e-05	5.440	6	23	94
GO:0005839	proteasome core complex	1.09e-08	1.77e-04	7.240	4	11	18
GO:0000209	protein polyubiquitination	1.37e-08	2.24e-04	5.136	6	21	116
GO:0004298	threonine-type endopeptidase activity	1.71e-08	2.80e-04	7.088	4	11	20
GO:0016071	mRNA metabolic process	2.30e-08	3.75e-04	4.416	7	34	223
GO:0016070	RNA metabolic process	4.64e-08	7.57e-04	4.268	7	34	247
GO:0042981	regulation of apoptotic process	6.66e-08	1.09e-03	4.756	6	26	151
GO:0044281	small molecule metabolic process	7.14e-07	1.16e-02	2.530	11	57	1295
GO:0005654	nucleoplasm	1.46e-06	2.38e-02	2.635	10	83	1095
GO:0070062	extracellular vesicular exosome	1.75e-06	2.85e-02	1.920	14	98	2516
GO:0045252	oxoglutarate dehydrogenase complex	2.07e-06	3.38e-02	9.409	2	2	2
GO:0010467	gene expression	3.14e-06	5.12e-02	3.024	8	58	669
GO:0005829	cytosol	1.54e-05	2.51e-01	1.787	13	125	2562
GO:0043066	negative regulation of apoptotic process	3.02e-05	4.93e-01	3.236	6	30	433
GO:0006554	lysine catabolic process	5.77e-05	9.42e-01	7.409	2	2	8
GO:0005838	proteasome regulatory particle	1.36e-04	1.00e+00	6.825	2	7	12
GO:0006915	apoptotic process	1.40e-04	1.00e+00	2.837	6	34	571
GO:0022624	proteasome accessory complex	2.78e-04	1.00e+00	6.322	2	9	17
GO:0043022	ribosome binding	7.65e-04	1.00e+00	5.602	2	3	28
GO:0006099	tricarboxylic acid cycle	8.21e-04	1.00e+00	5.551	2	3	29
GO:0005634	nucleus	8.29e-04	1.00e+00	1.079	15	131	4828
GO:0018467	formaldehyde dehydrogenase activity	1.47e-03	1.00e+00	9.409	1	1	1
GO:0050046	lathosterol oxidase activity	1.47e-03	1.00e+00	9.409	1	1	1
GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity	1.47e-03	1.00e+00	9.409	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	1.47e-03	1.00e+00	9.409	1	1	1
GO:0033490	cholesterol biosynthetic process via lathosterol	1.47e-03	1.00e+00	9.409	1	1	1
GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity	1.47e-03	1.00e+00	9.409	1	1	1
GO:0090230	regulation of centromere complex assembly	1.47e-03	1.00e+00	9.409	1	1	1
GO:0004632	phosphopantothenate--cysteine ligase activity	1.47e-03	1.00e+00	9.409	1	1	1
GO:0000054	ribosomal subunit export from nucleus	1.47e-03	1.00e+00	9.409	1	1	1
GO:0019521	D-gluconate metabolic process	1.47e-03	1.00e+00	9.409	1	1	1
GO:0031625	ubiquitin protein ligase binding	2.25e-03	1.00e+00	3.503	3	13	180
GO:0006091	generation of precursor metabolites and energy	2.53e-03	1.00e+00	4.737	2	3	51
GO:0016020	membrane	2.58e-03	1.00e+00	1.640	8	80	1746
GO:0004832	valine-tRNA ligase activity	2.94e-03	1.00e+00	8.409	1	1	2
GO:0097286	iron ion import	2.94e-03	1.00e+00	8.409	1	1	2
GO:0006407	rRNA export from nucleus	2.94e-03	1.00e+00	8.409	1	1	2
GO:0006438	valyl-tRNA aminoacylation	2.94e-03	1.00e+00	8.409	1	1	2
GO:0046294	formaldehyde catabolic process	2.94e-03	1.00e+00	8.409	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	2.94e-03	1.00e+00	8.409	1	1	2
GO:0000248	C-5 sterol desaturase activity	2.94e-03	1.00e+00	8.409	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.94e-03	1.00e+00	8.409	1	1	2
GO:0004998	transferrin receptor activity	2.94e-03	1.00e+00	8.409	1	1	2
GO:0019322	pentose biosynthetic process	2.94e-03	1.00e+00	8.409	1	1	2
GO:0031134	sister chromatid biorientation	2.94e-03	1.00e+00	8.409	1	1	2
GO:0005055	laminin receptor activity	2.94e-03	1.00e+00	8.409	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	2.94e-03	1.00e+00	8.409	1	2	2
GO:0018119	peptidyl-cysteine S-nitrosylation	4.41e-03	1.00e+00	7.825	1	1	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	4.41e-03	1.00e+00	7.825	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	4.41e-03	1.00e+00	7.825	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	4.41e-03	1.00e+00	7.825	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	4.41e-03	1.00e+00	7.825	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	4.41e-03	1.00e+00	7.825	1	1	3
GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine	4.41e-03	1.00e+00	7.825	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	4.41e-03	1.00e+00	7.825	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.87e-03	1.00e+00	7.409	1	1	4
GO:0000212	meiotic spindle organization	5.87e-03	1.00e+00	7.409	1	1	4
GO:0030686	90S preribosome	5.87e-03	1.00e+00	7.409	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	5.87e-03	1.00e+00	7.409	1	1	4
GO:0019788	NEDD8 ligase activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0051409	response to nitrosative stress	5.87e-03	1.00e+00	7.409	1	1	4
GO:0006068	ethanol catabolic process	5.87e-03	1.00e+00	7.409	1	1	4
GO:0006104	succinyl-CoA metabolic process	5.87e-03	1.00e+00	7.409	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	5.87e-03	1.00e+00	7.409	1	1	4
GO:0043550	regulation of lipid kinase activity	5.87e-03	1.00e+00	7.409	1	1	4
GO:0035189	Rb-E2F complex	5.87e-03	1.00e+00	7.409	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	5.87e-03	1.00e+00	7.409	1	1	4
GO:0034349	glial cell apoptotic process	5.87e-03	1.00e+00	7.409	1	1	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	7.33e-03	1.00e+00	7.088	1	2	5
GO:0042256	mature ribosome assembly	7.33e-03	1.00e+00	7.088	1	1	5
GO:2000001	regulation of DNA damage checkpoint	7.33e-03	1.00e+00	7.088	1	1	5
GO:0008622	epsilon DNA polymerase complex	7.33e-03	1.00e+00	7.088	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	7.33e-03	1.00e+00	7.088	1	1	5
GO:0043248	proteasome assembly	7.33e-03	1.00e+00	7.088	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	7.33e-03	1.00e+00	7.088	1	1	5
GO:0004022	alcohol dehydrogenase (NAD) activity	7.33e-03	1.00e+00	7.088	1	1	5
GO:0030891	VCB complex	7.33e-03	1.00e+00	7.088	1	2	5
GO:0005827	polar microtubule	7.33e-03	1.00e+00	7.088	1	1	5
GO:0000730	DNA recombinase assembly	7.33e-03	1.00e+00	7.088	1	3	5
GO:0005638	lamin filament	7.33e-03	1.00e+00	7.088	1	1	5
GO:0006734	NADH metabolic process	7.33e-03	1.00e+00	7.088	1	1	5
GO:0030976	thiamine pyrophosphate binding	7.33e-03	1.00e+00	7.088	1	1	5
GO:0016605	PML body	8.00e-03	1.00e+00	3.886	2	5	92
GO:0005200	structural constituent of cytoskeleton	8.17e-03	1.00e+00	3.870	2	7	93
GO:0043353	enucleate erythrocyte differentiation	8.79e-03	1.00e+00	6.825	1	1	6
GO:0009108	coenzyme biosynthetic process	8.79e-03	1.00e+00	6.825	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	8.79e-03	1.00e+00	6.825	1	1	6
GO:0021860	pyramidal neuron development	8.79e-03	1.00e+00	6.825	1	1	6
GO:0043023	ribosomal large subunit binding	8.79e-03	1.00e+00	6.825	1	2	6
GO:0031466	Cul5-RING ubiquitin ligase complex	8.79e-03	1.00e+00	6.825	1	1	6
GO:0021695	cerebellar cortex development	8.79e-03	1.00e+00	6.825	1	1	6
GO:0030957	Tat protein binding	8.79e-03	1.00e+00	6.825	1	4	6
GO:0000028	ribosomal small subunit assembly	1.03e-02	1.00e+00	6.602	1	1	7
GO:0002161	aminoacyl-tRNA editing activity	1.03e-02	1.00e+00	6.602	1	2	7
GO:0031462	Cul2-RING ubiquitin ligase complex	1.03e-02	1.00e+00	6.602	1	2	7
GO:0000930	gamma-tubulin complex	1.03e-02	1.00e+00	6.602	1	1	7
GO:0016018	cyclosporin A binding	1.03e-02	1.00e+00	6.602	1	1	7
GO:0005515	protein binding	1.14e-02	1.00e+00	0.735	15	172	6127
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.17e-02	1.00e+00	6.409	1	2	8
GO:0070688	MLL5-L complex	1.17e-02	1.00e+00	6.409	1	1	8
GO:0045116	protein neddylation	1.17e-02	1.00e+00	6.409	1	2	8
GO:0019773	proteasome core complex, alpha-subunit complex	1.17e-02	1.00e+00	6.409	1	5	8
GO:0072562	blood microparticle	1.25e-02	1.00e+00	3.551	2	4	116
GO:0044237	cellular metabolic process	1.29e-02	1.00e+00	3.527	2	3	118
GO:0003016	respiratory system process	1.32e-02	1.00e+00	6.240	1	1	9
GO:0015937	coenzyme A biosynthetic process	1.32e-02	1.00e+00	6.240	1	1	9
GO:0097284	hepatocyte apoptotic process	1.32e-02	1.00e+00	6.240	1	2	9
GO:0000075	cell cycle checkpoint	1.32e-02	1.00e+00	6.240	1	2	9
GO:0006450	regulation of translational fidelity	1.46e-02	1.00e+00	6.088	1	2	10
GO:0015939	pantothenate metabolic process	1.46e-02	1.00e+00	6.088	1	1	10
GO:0006069	ethanol oxidation	1.46e-02	1.00e+00	6.088	1	1	10
GO:0051775	response to redox state	1.46e-02	1.00e+00	6.088	1	1	10
GO:0021756	striatum development	1.46e-02	1.00e+00	6.088	1	1	10
GO:0006413	translational initiation	1.57e-02	1.00e+00	3.376	2	12	131
GO:0006098	pentose-phosphate shunt	1.61e-02	1.00e+00	5.950	1	3	11
GO:0010569	regulation of double-strand break repair via homologous recombination	1.61e-02	1.00e+00	5.950	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.61e-02	1.00e+00	5.950	1	3	11
GO:0042551	neuron maturation	1.61e-02	1.00e+00	5.950	1	2	11
GO:0045651	positive regulation of macrophage differentiation	1.61e-02	1.00e+00	5.950	1	2	11
GO:0051146	striated muscle cell differentiation	1.75e-02	1.00e+00	5.825	1	1	12
GO:0021794	thalamus development	1.75e-02	1.00e+00	5.825	1	1	12
GO:0042273	ribosomal large subunit biogenesis	1.90e-02	1.00e+00	5.709	1	4	13
GO:0005662	DNA replication factor A complex	1.90e-02	1.00e+00	5.709	1	3	13
GO:0045780	positive regulation of bone resorption	1.90e-02	1.00e+00	5.709	1	1	13
GO:0030234	enzyme regulator activity	1.90e-02	1.00e+00	5.709	1	3	13
GO:0006457	protein folding	2.00e-02	1.00e+00	3.190	2	8	149
GO:0035267	NuA4 histone acetyltransferase complex	2.04e-02	1.00e+00	5.602	1	4	14
GO:0005504	fatty acid binding	2.04e-02	1.00e+00	5.602	1	1	14
GO:0007020	microtubule nucleation	2.04e-02	1.00e+00	5.602	1	1	14
GO:0045445	myoblast differentiation	2.18e-02	1.00e+00	5.503	1	2	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	2.18e-02	1.00e+00	5.503	1	1	15
GO:0016514	SWI/SNF complex	2.18e-02	1.00e+00	5.503	1	3	15
GO:0042176	regulation of protein catabolic process	2.33e-02	1.00e+00	5.409	1	3	16
GO:0050998	nitric-oxide synthase binding	2.33e-02	1.00e+00	5.409	1	1	16
GO:0006103	2-oxoglutarate metabolic process	2.33e-02	1.00e+00	5.409	1	1	16
GO:0010243	response to organonitrogen compound	2.47e-02	1.00e+00	5.322	1	2	17
GO:0045070	positive regulation of viral genome replication	2.47e-02	1.00e+00	5.322	1	1	17
GO:0045777	positive regulation of blood pressure	2.47e-02	1.00e+00	5.322	1	1	17
GO:0031122	cytoplasmic microtubule organization	2.62e-02	1.00e+00	5.240	1	2	18
GO:0035861	site of double-strand break	2.62e-02	1.00e+00	5.240	1	1	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.76e-02	1.00e+00	5.162	1	1	19
GO:0048863	stem cell differentiation	2.76e-02	1.00e+00	5.162	1	1	19
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.90e-02	1.00e+00	5.088	1	2	20
GO:0006298	mismatch repair	2.90e-02	1.00e+00	5.088	1	6	20
GO:0000718	nucleotide-excision repair, DNA damage removal	3.04e-02	1.00e+00	5.017	1	5	21
GO:0005730	nucleolus	3.16e-02	1.00e+00	1.277	6	70	1684
GO:0030316	osteoclast differentiation	3.19e-02	1.00e+00	4.950	1	2	22
GO:0006297	nucleotide-excision repair, DNA gap filling	3.19e-02	1.00e+00	4.950	1	5	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	3.19e-02	1.00e+00	4.950	1	3	22
GO:0032201	telomere maintenance via semi-conservative replication	3.19e-02	1.00e+00	4.950	1	7	22
GO:0030863	cortical cytoskeleton	3.19e-02	1.00e+00	4.950	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	3.19e-02	1.00e+00	4.950	1	4	22
GO:0031463	Cul3-RING ubiquitin ligase complex	3.33e-02	1.00e+00	4.886	1	2	23
GO:0043236	laminin binding	3.33e-02	1.00e+00	4.886	1	1	23
GO:0006513	protein monoubiquitination	3.33e-02	1.00e+00	4.886	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	3.33e-02	1.00e+00	4.886	1	4	23
GO:0045879	negative regulation of smoothened signaling pathway	3.33e-02	1.00e+00	4.886	1	1	23
GO:0000794	condensed nuclear chromosome	3.47e-02	1.00e+00	4.825	1	2	24
GO:0000722	telomere maintenance via recombination	3.76e-02	1.00e+00	4.709	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.76e-02	1.00e+00	4.709	1	2	26
GO:0048565	digestive tract development	3.90e-02	1.00e+00	4.655	1	1	27
GO:0031492	nucleosomal DNA binding	4.04e-02	1.00e+00	4.602	1	4	28
GO:0019894	kinesin binding	4.04e-02	1.00e+00	4.602	1	1	28
GO:0019005	SCF ubiquitin ligase complex	4.18e-02	1.00e+00	4.551	1	1	29
GO:0003887	DNA-directed DNA polymerase activity	4.18e-02	1.00e+00	4.551	1	3	29
GO:0071897	DNA biosynthetic process	4.18e-02	1.00e+00	4.551	1	2	29
GO:0007346	regulation of mitotic cell cycle	4.32e-02	1.00e+00	4.503	1	3	30
GO:0006271	DNA strand elongation involved in DNA replication	4.46e-02	1.00e+00	4.455	1	9	31
GO:0007093	mitotic cell cycle checkpoint	4.46e-02	1.00e+00	4.455	1	2	31
GO:0005759	mitochondrial matrix	4.56e-02	1.00e+00	2.545	2	12	233
GO:0050661	NADP binding	4.60e-02	1.00e+00	4.409	1	1	32
GO:0051219	phosphoprotein binding	4.60e-02	1.00e+00	4.409	1	3	32
GO:0033572	transferrin transport	4.60e-02	1.00e+00	4.409	1	6	32
GO:0031072	heat shock protein binding	4.74e-02	1.00e+00	4.365	1	2	33
GO:0000413	protein peptidyl-prolyl isomerization	4.89e-02	1.00e+00	4.322	1	1	34
GO:0006695	cholesterol biosynthetic process	4.89e-02	1.00e+00	4.322	1	2	34
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4.89e-02	1.00e+00	4.322	1	1	34
GO:0034332	adherens junction organization	5.17e-02	1.00e+00	4.240	1	1	36
GO:0051402	neuron apoptotic process	5.17e-02	1.00e+00	4.240	1	2	36
GO:0001895	retina homeostasis	5.17e-02	1.00e+00	4.240	1	1	36
GO:0001102	RNA polymerase II activating transcription factor binding	5.30e-02	1.00e+00	4.200	1	4	37
GO:0051084	'de novo' posttranslational protein folding	5.30e-02	1.00e+00	4.200	1	4	37
GO:0006633	fatty acid biosynthetic process	5.30e-02	1.00e+00	4.200	1	2	37
GO:0070527	platelet aggregation	5.44e-02	1.00e+00	4.162	1	2	38
GO:0050681	androgen receptor binding	5.44e-02	1.00e+00	4.162	1	4	38
GO:0021766	hippocampus development	5.58e-02	1.00e+00	4.124	1	4	39
GO:0008026	ATP-dependent helicase activity	5.58e-02	1.00e+00	4.124	1	3	39
GO:0006284	base-excision repair	5.58e-02	1.00e+00	4.124	1	7	39
GO:0006096	glycolytic process	5.58e-02	1.00e+00	4.124	1	4	39
GO:0022627	cytosolic small ribosomal subunit	5.58e-02	1.00e+00	4.124	1	3	39
GO:0006281	DNA repair	5.70e-02	1.00e+00	2.365	2	22	264
GO:0000781	chromosome, telomeric region	5.72e-02	1.00e+00	4.088	1	2	40
GO:0030521	androgen receptor signaling pathway	5.86e-02	1.00e+00	4.052	1	2	41
GO:0006418	tRNA aminoacylation for protein translation	6.00e-02	1.00e+00	4.017	1	5	42
GO:0035914	skeletal muscle cell differentiation	6.00e-02	1.00e+00	4.017	1	1	42
GO:0014070	response to organic cyclic compound	6.14e-02	1.00e+00	3.983	1	3	43
GO:0005739	mitochondrion	6.40e-02	1.00e+00	1.379	4	24	1046
GO:0043966	histone H3 acetylation	6.42e-02	1.00e+00	3.918	1	2	45
GO:0021762	substantia nigra development	6.55e-02	1.00e+00	3.886	1	1	46
GO:0001047	core promoter binding	6.55e-02	1.00e+00	3.886	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	6.55e-02	1.00e+00	3.886	1	8	46
GO:0003743	translation initiation factor activity	6.97e-02	1.00e+00	3.795	1	4	49
GO:0044822	poly(A) RNA binding	7.00e-02	1.00e+00	1.335	4	50	1078
GO:0001523	retinoid metabolic process	7.10e-02	1.00e+00	3.766	1	2	50
GO:0005905	coated pit	7.24e-02	1.00e+00	3.737	1	2	51
GO:0003684	damaged DNA binding	7.24e-02	1.00e+00	3.737	1	11	51
GO:0003725	double-stranded RNA binding	7.65e-02	1.00e+00	3.655	1	6	54
GO:0019900	kinase binding	7.65e-02	1.00e+00	3.655	1	1	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	7.65e-02	1.00e+00	3.655	1	5	54
GO:0050680	negative regulation of epithelial cell proliferation	7.65e-02	1.00e+00	3.655	1	1	54
GO:0000226	microtubule cytoskeleton organization	7.79e-02	1.00e+00	3.628	1	3	55
GO:0000932	cytoplasmic mRNA processing body	7.92e-02	1.00e+00	3.602	1	3	56
GO:0006879	cellular iron ion homeostasis	8.06e-02	1.00e+00	3.577	1	5	57
GO:0000724	double-strand break repair via homologous recombination	8.06e-02	1.00e+00	3.577	1	6	57
GO:0051087	chaperone binding	8.33e-02	1.00e+00	3.527	1	6	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	8.33e-02	1.00e+00	3.527	1	4	59
GO:0045216	cell-cell junction organization	8.33e-02	1.00e+00	3.527	1	2	59
GO:0000723	telomere maintenance	8.33e-02	1.00e+00	3.527	1	8	59
GO:0031966	mitochondrial membrane	8.33e-02	1.00e+00	3.527	1	1	59
GO:0006302	double-strand break repair	8.74e-02	1.00e+00	3.455	1	8	62
GO:0019903	protein phosphatase binding	8.87e-02	1.00e+00	3.432	1	4	63
GO:0006469	negative regulation of protein kinase activity	9.14e-02	1.00e+00	3.387	1	2	65
GO:0001558	regulation of cell growth	9.27e-02	1.00e+00	3.365	1	4	66
GO:0006338	chromatin remodeling	9.54e-02	1.00e+00	3.322	1	4	68
GO:0009055	electron carrier activity	9.54e-02	1.00e+00	3.322	1	1	68
GO:0006289	nucleotide-excision repair	9.67e-02	1.00e+00	3.301	1	12	69
GO:0003697	single-stranded DNA binding	9.67e-02	1.00e+00	3.301	1	9	69
GO:0034329	cell junction assembly	9.94e-02	1.00e+00	3.260	1	1	71
GO:0055037	recycling endosome	1.02e-01	1.00e+00	3.220	1	2	73
GO:0000785	chromatin	1.02e-01	1.00e+00	3.220	1	5	73
GO:0006767	water-soluble vitamin metabolic process	1.05e-01	1.00e+00	3.181	1	3	75
GO:0007265	Ras protein signal transduction	1.05e-01	1.00e+00	3.181	1	3	75
GO:0031175	neuron projection development	1.05e-01	1.00e+00	3.181	1	1	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	1.06e-01	1.00e+00	3.162	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	1.07e-01	1.00e+00	3.143	1	5	77
GO:0006766	vitamin metabolic process	1.09e-01	1.00e+00	3.124	1	3	78
GO:0071013	catalytic step 2 spliceosome	1.10e-01	1.00e+00	3.106	1	7	79
GO:0019083	viral transcription	1.13e-01	1.00e+00	3.070	1	8	81
GO:0047485	protein N-terminus binding	1.19e-01	1.00e+00	2.983	1	4	86
GO:0006898	receptor-mediated endocytosis	1.19e-01	1.00e+00	2.983	1	2	86
GO:0006415	translational termination	1.20e-01	1.00e+00	2.967	1	8	87
GO:0042470	melanosome	1.27e-01	1.00e+00	2.886	1	10	92
GO:0006928	cellular component movement	1.27e-01	1.00e+00	2.886	1	7	92
GO:0006414	translational elongation	1.28e-01	1.00e+00	2.870	1	11	93
GO:0006364	rRNA processing	1.32e-01	1.00e+00	2.825	1	5	96
GO:0071456	cellular response to hypoxia	1.35e-01	1.00e+00	2.795	1	4	98
GO:0006629	lipid metabolic process	1.37e-01	1.00e+00	2.766	1	2	100
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.42e-01	1.00e+00	2.709	1	8	104
GO:0014069	postsynaptic density	1.45e-01	1.00e+00	2.682	1	1	106
GO:0016023	cytoplasmic membrane-bounded vesicle	1.46e-01	1.00e+00	2.668	1	3	107
GO:0042127	regulation of cell proliferation	1.51e-01	1.00e+00	2.615	1	4	111
GO:0015630	microtubule cytoskeleton	1.52e-01	1.00e+00	2.602	1	5	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.55e-01	1.00e+00	2.577	1	10	114
GO:0030529	ribonucleoprotein complex	1.55e-01	1.00e+00	2.577	1	8	114
GO:0005819	spindle	1.55e-01	1.00e+00	2.577	1	7	114
GO:0019058	viral life cycle	1.56e-01	1.00e+00	2.564	1	10	115
GO:0055114	oxidation-reduction process	1.57e-01	1.00e+00	1.500	2	11	481
GO:0042802	identical protein binding	1.62e-01	1.00e+00	1.470	2	18	491
GO:0044267	cellular protein metabolic process	1.64e-01	1.00e+00	1.458	2	24	495
GO:0032496	response to lipopolysaccharide	1.65e-01	1.00e+00	2.479	1	4	122
GO:0006325	chromatin organization	1.66e-01	1.00e+00	2.467	1	4	123
GO:0007568	aging	1.66e-01	1.00e+00	2.467	1	3	123
GO:0007219	Notch signaling pathway	1.69e-01	1.00e+00	2.444	1	4	125
GO:0006260	DNA replication	1.69e-01	1.00e+00	2.444	1	12	125
GO:0007050	cell cycle arrest	1.70e-01	1.00e+00	2.432	1	7	126
GO:0005506	iron ion binding	1.71e-01	1.00e+00	2.421	1	3	127
GO:0006511	ubiquitin-dependent protein catabolic process	1.71e-01	1.00e+00	2.421	1	5	127
GO:0009615	response to virus	1.77e-01	1.00e+00	2.365	1	6	132
GO:0000790	nuclear chromatin	1.78e-01	1.00e+00	2.354	1	7	133
GO:0031982	vesicle	1.80e-01	1.00e+00	2.343	1	10	134
GO:0000086	G2/M transition of mitotic cell cycle	1.83e-01	1.00e+00	2.311	1	7	137
GO:0003735	structural constituent of ribosome	1.88e-01	1.00e+00	2.270	1	8	141
GO:0061024	membrane organization	1.94e-01	1.00e+00	2.220	1	5	146
GO:0000398	mRNA splicing, via spliceosome	2.17e-01	1.00e+00	2.043	1	12	165
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2.20e-01	1.00e+00	2.017	1	5	168
GO:0030424	axon	2.25e-01	1.00e+00	1.983	1	3	172
GO:0005768	endosome	2.27e-01	1.00e+00	1.967	1	5	174
GO:0009897	external side of plasma membrane	2.37e-01	1.00e+00	1.894	1	4	183
GO:0015629	actin cytoskeleton	2.37e-01	1.00e+00	1.894	1	5	183
GO:0032403	protein complex binding	2.40e-01	1.00e+00	1.878	1	7	185
GO:0003924	GTPase activity	2.60e-01	1.00e+00	1.744	1	9	203
GO:0006184	GTP catabolic process	2.78e-01	1.00e+00	1.628	1	9	220
GO:0006412	translation	2.94e-01	1.00e+00	1.533	1	15	235
GO:0003713	transcription coactivator activity	2.98e-01	1.00e+00	1.509	1	10	239
GO:0008134	transcription factor binding	3.06e-01	1.00e+00	1.467	1	8	246
GO:0004842	ubiquitin-protein transferase activity	3.16e-01	1.00e+00	1.409	1	4	256
GO:0005524	ATP binding	3.21e-01	1.00e+00	0.591	3	46	1354
GO:0000166	nucleotide binding	3.32e-01	1.00e+00	1.322	1	6	272
GO:0005975	carbohydrate metabolic process	3.34e-01	1.00e+00	1.311	1	5	274
GO:0019899	enzyme binding	3.48e-01	1.00e+00	1.240	1	11	288
GO:0016567	protein ubiquitination	3.59e-01	1.00e+00	1.185	1	5	299
GO:0043234	protein complex	3.60e-01	1.00e+00	1.181	1	17	300
GO:0006200	ATP catabolic process	3.62e-01	1.00e+00	1.166	1	14	303
GO:0005856	cytoskeleton	3.70e-01	1.00e+00	1.129	1	8	311
GO:0019901	protein kinase binding	3.78e-01	1.00e+00	1.088	1	21	320
GO:0007411	axon guidance	3.85e-01	1.00e+00	1.056	1	9	327
GO:0005525	GTP binding	3.86e-01	1.00e+00	1.052	1	11	328
GO:0043231	intracellular membrane-bounded organelle	3.90e-01	1.00e+00	1.034	1	8	332
GO:0005813	centrosome	3.96e-01	1.00e+00	1.004	1	12	339
GO:0003723	RNA binding	4.10e-01	1.00e+00	0.938	1	19	355
GO:0043565	sequence-specific DNA binding	4.19e-01	1.00e+00	0.898	1	4	365
GO:0005925	focal adhesion	4.23e-01	1.00e+00	0.878	1	18	370
GO:0007155	cell adhesion	4.36e-01	1.00e+00	0.825	1	8	384
GO:0005615	extracellular space	4.43e-01	1.00e+00	0.429	2	17	1010
GO:0046982	protein heterodimerization activity	4.48e-01	1.00e+00	0.769	1	11	399
GO:0009986	cell surface	4.67e-01	1.00e+00	0.688	1	9	422
GO:0045892	negative regulation of transcription, DNA-templated	4.69e-01	1.00e+00	0.682	1	14	424
GO:0008270	zinc ion binding	4.71e-01	1.00e+00	0.350	2	12	1067
GO:0007596	blood coagulation	5.00e-01	1.00e+00	0.551	1	14	464
GO:0045893	positive regulation of transcription, DNA-templated	5.17e-01	1.00e+00	0.482	1	17	487
GO:0055085	transmembrane transport	5.36e-01	1.00e+00	0.404	1	8	514
GO:0048471	perinuclear region of cytoplasm	5.43e-01	1.00e+00	0.379	1	12	523
GO:0005737	cytoplasm	5.49e-01	1.00e+00	0.037	6	98	3976
GO:0045087	innate immune response	6.03e-01	1.00e+00	0.143	1	20	616
GO:0042803	protein homodimerization activity	6.04e-01	1.00e+00	0.140	1	11	617
GO:0005789	endoplasmic reticulum membrane	6.15e-01	1.00e+00	0.097	1	10	636
GO:0005794	Golgi apparatus	6.23e-01	1.00e+00	0.065	1	14	650
GO:0003700	sequence-specific DNA binding transcription factor activity	6.76e-01	1.00e+00	-0.137	1	11	748
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	7.06e-01	1.00e+00	-0.254	1	19	811
GO:0005887	integral component of plasma membrane	7.67e-01	1.00e+00	-0.499	1	7	961
GO:0005576	extracellular region	7.97e-01	1.00e+00	-0.625	1	9	1049
GO:0006355	regulation of transcription, DNA-templated	8.14e-01	1.00e+00	-0.699	1	17	1104
GO:0003677	DNA binding	8.74e-01	1.00e+00	-0.990	1	26	1351
GO:0046872	metal ion binding	8.96e-01	1.00e+00	-1.107	1	24	1465
GO:0006351	transcription, DNA-templated	9.14e-01	1.00e+00	-1.221	1	25	1585
GO:0005886	plasma membrane	9.38e-01	1.00e+00	-1.059	2	38	2834
GO:0016021	integral component of membrane	9.81e-01	1.00e+00	-1.868	1	15	2483

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-6309

Interacting subnets

Genes (24)

Interactions (62)

Related GO terms (340)