meta-int-snw-6240

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-317781	wolf-screen-ratio-mammosphere-adherent	0.823	1.13e-06	3.23e-03	6.07e-03	9	9
int-snw-6240	wolf-screen-ratio-mammosphere-adherent	0.989	1.11e-17	7.18e-04	1.60e-02	12	12
reg-snw-55660	wolf-screen-ratio-mammosphere-adherent	0.830	8.54e-07	2.78e-03	5.31e-03	6	6

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-6240 subnetwork

Genes (21)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMA2	5683	112	1.093	1.106	108	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
PSMC3	5702	51	0.719	1.002	276	Yes	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
RRM1	6240	15	0.587	0.872	117	Yes	-
PSMA1	5682	100	0.996	0.878	152	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
DDX51	317781	53	0.059	0.823	210	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
EIF6	3692	67	0.700	0.876	316	Yes	-
RSL24D1	51187	38	1.300	1.020	59	Yes	-
ACO2	50	65	1.000	1.076	191	Yes	-
PSMD1	5707	86	0.836	0.830	118	Yes	-
PSMD13	5719	56	0.848	0.801	114	Yes	-
PSMD3	5709	100	0.986	1.106	201	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
TUBG1	7283	98	0.974	0.973	91	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-
HSPD1	3329	70	0.913	1.035	325	Yes	-
PRPF40A	55660	25	0.423	0.830	106	Yes	-

Interactions (71)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMA1	5682	PSMD13	5719	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
PSMB2	5690	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
PSMA2	5683	PSMD13	5719	pp	--	int.I2D: YeastLow
PSMC3	5702	VARS	7407	pp	--	int.I2D: BioGrid_Yeast
PSMD1	5707	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMD1	5707	PSMD13	5719	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, MINT_Yeast, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
ACTB	60	PSMD13	5719	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMD1	5707	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACO2	50	HSPD1	3329	pp	--	int.I2D: IntAct_Yeast
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMB2	5690	PSMD13	5719	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMC3	5702	PSMD3	5709	pd	<	reg.ITFP.txt: no annot
PSMC3	5702	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, Krogan_NonCore, YeastHigh
EIF6	3692	RRM1	6240	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
EIF6	3692	PGD	5226	pp	--	int.I2D: YeastLow
PSMD1	5707	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
HSPD1	3329	EIF6	3692	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMA2	5683	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
TUBG1	7283	VARS	7407	pd	<	reg.ITFP.txt: no annot
HSPD1	3329	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot
ACO2	50	EIF6	3692	pp	--	int.I2D: YeastLow
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMA2	5683	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMD3	5709	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMC3	5702	PSMD13	5719	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
PSMB7	5695	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
VARS	7407	DDX51	317781	pd	<>	reg.ITFP.txt: no annot
PSMD3	5709	VARS	7407	pd	<>	reg.ITFP.txt: no annot
PSMB7	5695	PSMD1	5707	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMC3	5702	PSMD1	5707	pp	--	int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
PSMA1	5682	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
PSMD11	5717	TUBG1	7283	pd	>	reg.ITFP.txt: no annot
ACTB	60	PSMC3	5702	pp	--	int.I2D: BioGrid_Yeast
PSMC3	5702	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMC3	5702	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh
PSMA1	5682	PSMD1	5707	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
EIF6	3692	RSL24D1	51187	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMA1	5682	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
PSMB7	5695	PSMD13	5719	pd	<	reg.ITFP.txt: no annot
PSMD13	5719	RRM1	6240	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
PSMC3	5702	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	PSMD13	5719	pp	--	int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG
PSMD3	5709	PSMD13	5719	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
EIF6	3692	DDX51	317781	pd	<	reg.ITFP.txt: no annot
PSMD1	5707	PRPF40A	55660	pd	<	reg.ITFP.txt: no annot
PSMD11	5717	RRM1	6240	pd	>	reg.ITFP.txt: no annot
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
PSMB2	5690	PSMD1	5707	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (227)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	3.17e-18	5.18e-14	7.128	9	21	50
GO:0000502	proteasome complex	1.34e-17	2.19e-13	6.914	9	22	58
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.01e-17	6.54e-13	6.750	9	24	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.01e-17	6.54e-13	6.750	9	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.12e-17	1.33e-12	6.643	9	24	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.21e-16	1.98e-12	6.582	9	23	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.38e-16	2.25e-12	6.563	9	24	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.01e-16	3.27e-12	6.505	9	23	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	2.56e-16	4.17e-12	6.468	9	25	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.31e-15	2.13e-11	6.217	9	23	94
GO:0000209	protein polyubiquitination	9.24e-15	1.51e-10	5.914	9	21	116
GO:0000082	G1/S transition of mitotic cell cycle	9.83e-14	1.60e-09	5.543	9	33	150
GO:0042981	regulation of apoptotic process	1.04e-13	1.70e-09	5.534	9	26	151
GO:0034641	cellular nitrogen compound metabolic process	4.45e-13	7.26e-09	5.304	9	25	177
GO:0000278	mitotic cell cycle	4.48e-13	7.31e-09	4.425	11	52	398
GO:0016071	mRNA metabolic process	3.60e-12	5.88e-08	4.971	9	34	223
GO:0016070	RNA metabolic process	9.03e-12	1.47e-07	4.824	9	34	247
GO:0016032	viral process	1.23e-11	2.01e-07	3.985	11	55	540
GO:0022624	proteasome accessory complex	1.29e-11	2.11e-07	7.837	5	9	17
GO:0043066	negative regulation of apoptotic process	4.23e-11	6.91e-07	4.166	10	30	433
GO:0005838	proteasome regulatory particle	9.96e-10	1.63e-05	8.017	4	7	12
GO:0005829	cytosol	1.20e-09	1.96e-05	2.279	16	125	2562
GO:0005654	nucleoplasm	1.31e-09	2.14e-05	3.090	12	83	1095
GO:0010467	gene expression	2.93e-09	4.79e-05	3.538	10	58	669
GO:0005839	proteasome core complex	6.12e-09	1.00e-04	7.432	4	11	18
GO:0044281	small molecule metabolic process	8.87e-09	1.45e-04	2.848	12	57	1295
GO:0004298	threonine-type endopeptidase activity	9.68e-09	1.58e-04	7.280	4	11	20
GO:0006915	apoptotic process	1.49e-08	2.43e-04	3.615	9	34	571
GO:0070062	extracellular vesicular exosome	1.61e-06	2.64e-02	2.006	13	98	2516
GO:0016020	membrane	2.22e-05	3.62e-01	2.154	10	80	1746
GO:0019773	proteasome core complex, alpha-subunit complex	4.39e-05	7.17e-01	7.602	2	5	8
GO:0030234	enzyme regulator activity	1.22e-04	1.00e+00	6.902	2	3	13
GO:0042176	regulation of protein catabolic process	1.87e-04	1.00e+00	6.602	2	3	16
GO:0005730	nucleolus	7.49e-04	1.00e+00	1.884	8	70	1684
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.29e-03	1.00e+00	9.602	1	1	1
GO:0048291	isotype switching to IgG isotypes	1.29e-03	1.00e+00	9.602	1	1	1
GO:0000054	ribosomal subunit export from nucleus	1.29e-03	1.00e+00	9.602	1	1	1
GO:0019521	D-gluconate metabolic process	1.29e-03	1.00e+00	9.602	1	1	1
GO:0002368	B cell cytokine production	1.29e-03	1.00e+00	9.602	1	1	1
GO:0000932	cytoplasmic mRNA processing body	2.33e-03	1.00e+00	4.795	2	3	56
GO:0004832	valine-tRNA ligase activity	2.57e-03	1.00e+00	8.602	1	1	2
GO:0051538	3 iron, 4 sulfur cluster binding	2.57e-03	1.00e+00	8.602	1	1	2
GO:0019322	pentose biosynthetic process	2.57e-03	1.00e+00	8.602	1	1	2
GO:0003994	aconitate hydratase activity	2.57e-03	1.00e+00	8.602	1	1	2
GO:0006438	valyl-tRNA aminoacylation	2.57e-03	1.00e+00	8.602	1	1	2
GO:0007127	meiosis I	2.57e-03	1.00e+00	8.602	1	1	2
GO:0009263	deoxyribonucleotide biosynthetic process	3.86e-03	1.00e+00	8.017	1	1	3
GO:0006458	'de novo' protein folding	3.86e-03	1.00e+00	8.017	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	3.86e-03	1.00e+00	8.017	1	1	3
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	3.86e-03	1.00e+00	8.017	1	1	3
GO:0030135	coated vesicle	3.86e-03	1.00e+00	8.017	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	3.86e-03	1.00e+00	8.017	1	1	3
GO:0000212	meiotic spindle organization	5.14e-03	1.00e+00	7.602	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	5.14e-03	1.00e+00	7.602	1	1	4
GO:0019788	NEDD8 ligase activity	5.14e-03	1.00e+00	7.602	1	1	4
GO:0005524	ATP binding	5.90e-03	1.00e+00	1.784	6	46	1354
GO:0005200	structural constituent of cytoskeleton	6.29e-03	1.00e+00	4.063	2	7	93
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	6.42e-03	1.00e+00	7.280	1	2	5
GO:0031461	cullin-RING ubiquitin ligase complex	6.42e-03	1.00e+00	7.280	1	1	5
GO:0042256	mature ribosome assembly	6.42e-03	1.00e+00	7.280	1	1	5
GO:0043248	proteasome assembly	6.42e-03	1.00e+00	7.280	1	1	5
GO:0046696	lipopolysaccharide receptor complex	6.42e-03	1.00e+00	7.280	1	1	5
GO:0006102	isocitrate metabolic process	6.42e-03	1.00e+00	7.280	1	1	5
GO:0030891	VCB complex	6.42e-03	1.00e+00	7.280	1	2	5
GO:0005827	polar microtubule	6.42e-03	1.00e+00	7.280	1	1	5
GO:0005638	lamin filament	6.42e-03	1.00e+00	7.280	1	1	5
GO:0006200	ATP catabolic process	6.58e-03	1.00e+00	2.944	3	14	303
GO:0003688	DNA replication origin binding	7.70e-03	1.00e+00	7.017	1	1	6
GO:0030957	Tat protein binding	7.70e-03	1.00e+00	7.017	1	4	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	7.70e-03	1.00e+00	7.017	1	1	6
GO:0006101	citrate metabolic process	7.70e-03	1.00e+00	7.017	1	1	6
GO:0043023	ribosomal large subunit binding	7.70e-03	1.00e+00	7.017	1	2	6
GO:0005634	nucleus	7.70e-03	1.00e+00	0.950	12	131	4828
GO:0031466	Cul5-RING ubiquitin ligase complex	7.70e-03	1.00e+00	7.017	1	1	6
GO:0002161	aminoacyl-tRNA editing activity	8.97e-03	1.00e+00	6.795	1	2	7
GO:0000930	gamma-tubulin complex	8.97e-03	1.00e+00	6.795	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	8.97e-03	1.00e+00	6.795	1	2	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.02e-02	1.00e+00	6.602	1	2	8
GO:0070688	MLL5-L complex	1.02e-02	1.00e+00	6.602	1	1	8
GO:0045116	protein neddylation	1.02e-02	1.00e+00	6.602	1	2	8
GO:0006450	regulation of translational fidelity	1.28e-02	1.00e+00	6.280	1	2	10
GO:0043032	positive regulation of macrophage activation	1.28e-02	1.00e+00	6.280	1	1	10
GO:0051604	protein maturation	1.28e-02	1.00e+00	6.280	1	1	10
GO:0006098	pentose-phosphate shunt	1.41e-02	1.00e+00	6.143	1	3	11
GO:0021846	cell proliferation in forebrain	1.41e-02	1.00e+00	6.143	1	1	11
GO:0032727	positive regulation of interferon-alpha production	1.41e-02	1.00e+00	6.143	1	1	11
GO:0051290	protein heterotetramerization	1.41e-02	1.00e+00	6.143	1	2	11
GO:0016887	ATPase activity	1.45e-02	1.00e+00	3.432	2	7	144
GO:0042273	ribosomal large subunit biogenesis	1.66e-02	1.00e+00	5.902	1	4	13
GO:0001530	lipopolysaccharide binding	1.66e-02	1.00e+00	5.902	1	2	13
GO:0051131	chaperone-mediated protein complex assembly	1.66e-02	1.00e+00	5.902	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.79e-02	1.00e+00	5.795	1	4	14
GO:0007020	microtubule nucleation	1.79e-02	1.00e+00	5.795	1	1	14
GO:0032465	regulation of cytokinesis	1.79e-02	1.00e+00	5.795	1	1	14
GO:0042026	protein refolding	1.91e-02	1.00e+00	5.695	1	2	15
GO:0005515	protein binding	2.03e-02	1.00e+00	0.722	13	172	6127
GO:0050998	nitric-oxide synthase binding	2.04e-02	1.00e+00	5.602	1	1	16
GO:0010243	response to organonitrogen compound	2.17e-02	1.00e+00	5.515	1	2	17
GO:0050870	positive regulation of T cell activation	2.17e-02	1.00e+00	5.515	1	1	17
GO:0070064	proline-rich region binding	2.29e-02	1.00e+00	5.432	1	2	18
GO:0031122	cytoplasmic microtubule organization	2.29e-02	1.00e+00	5.432	1	2	18
GO:0015949	nucleobase-containing small molecule interconversion	2.29e-02	1.00e+00	5.432	1	2	18
GO:0032733	positive regulation of interleukin-10 production	2.42e-02	1.00e+00	5.354	1	1	19
GO:1903506	regulation of nucleic acid-templated transcription	2.42e-02	1.00e+00	5.354	1	1	19
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.42e-02	1.00e+00	5.354	1	1	19
GO:0048863	stem cell differentiation	2.42e-02	1.00e+00	5.354	1	1	19
GO:0030863	cortical cytoskeleton	2.79e-02	1.00e+00	5.143	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.79e-02	1.00e+00	5.143	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	2.92e-02	1.00e+00	5.079	1	4	23
GO:0031463	Cul3-RING ubiquitin ligase complex	2.92e-02	1.00e+00	5.079	1	2	23
GO:0006513	protein monoubiquitination	2.92e-02	1.00e+00	5.079	1	1	23
GO:0006206	pyrimidine nucleobase metabolic process	3.04e-02	1.00e+00	5.017	1	2	24
GO:0000794	condensed nuclear chromosome	3.04e-02	1.00e+00	5.017	1	2	24
GO:0005844	polysome	3.17e-02	1.00e+00	4.958	1	4	25
GO:0042100	B cell proliferation	3.17e-02	1.00e+00	4.958	1	1	25
GO:0042113	B cell activation	3.17e-02	1.00e+00	4.958	1	2	25
GO:0032735	positive regulation of interleukin-12 production	3.17e-02	1.00e+00	4.958	1	1	25
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.29e-02	1.00e+00	4.902	1	2	26
GO:0043022	ribosome binding	3.54e-02	1.00e+00	4.795	1	3	28
GO:0031492	nucleosomal DNA binding	3.54e-02	1.00e+00	4.795	1	4	28
GO:0019894	kinesin binding	3.54e-02	1.00e+00	4.795	1	1	28
GO:0005759	mitochondrial matrix	3.57e-02	1.00e+00	2.738	2	12	233
GO:0006099	tricarboxylic acid cycle	3.67e-02	1.00e+00	4.744	1	3	29
GO:0019005	SCF ubiquitin ligase complex	3.67e-02	1.00e+00	4.744	1	1	29
GO:0042254	ribosome biogenesis	3.79e-02	1.00e+00	4.695	1	1	30
GO:0050661	NADP binding	4.04e-02	1.00e+00	4.602	1	1	32
GO:1903507	negative regulation of nucleic acid-templated transcription	4.04e-02	1.00e+00	4.602	1	2	32
GO:0034332	adherens junction organization	4.53e-02	1.00e+00	4.432	1	1	36
GO:0001895	retina homeostasis	4.53e-02	1.00e+00	4.432	1	1	36
GO:0032755	positive regulation of interleukin-6 production	4.53e-02	1.00e+00	4.432	1	2	36
GO:0051084	'de novo' posttranslational protein folding	4.66e-02	1.00e+00	4.393	1	4	37
GO:0051539	4 iron, 4 sulfur cluster binding	4.66e-02	1.00e+00	4.393	1	3	37
GO:0070527	platelet aggregation	4.78e-02	1.00e+00	4.354	1	2	38
GO:0032729	positive regulation of interferon-gamma production	4.90e-02	1.00e+00	4.317	1	2	39
GO:0008026	ATP-dependent helicase activity	4.90e-02	1.00e+00	4.317	1	3	39
GO:0006418	tRNA aminoacylation for protein translation	5.27e-02	1.00e+00	4.210	1	5	42
GO:0042110	T cell activation	5.39e-02	1.00e+00	4.176	1	3	43
GO:0014070	response to organic cyclic compound	5.39e-02	1.00e+00	4.176	1	3	43
GO:0010212	response to ionizing radiation	5.39e-02	1.00e+00	4.176	1	1	43
GO:0043234	protein complex	5.62e-02	1.00e+00	2.373	2	17	300
GO:0021762	substantia nigra development	5.76e-02	1.00e+00	4.079	1	1	46
GO:0003743	translation initiation factor activity	6.12e-02	1.00e+00	3.987	1	4	49
GO:0006091	generation of precursor metabolites and energy	6.36e-02	1.00e+00	3.930	1	3	51
GO:0006986	response to unfolded protein	6.36e-02	1.00e+00	3.930	1	2	51
GO:0005905	coated pit	6.36e-02	1.00e+00	3.930	1	2	51
GO:0060041	retina development in camera-type eye	6.61e-02	1.00e+00	3.874	1	3	53
GO:0003725	double-stranded RNA binding	6.73e-02	1.00e+00	3.847	1	6	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	6.73e-02	1.00e+00	3.847	1	5	54
GO:0000226	microtubule cytoskeleton organization	6.85e-02	1.00e+00	3.821	1	3	55
GO:0002039	p53 binding	6.85e-02	1.00e+00	3.821	1	7	55
GO:0005813	centrosome	6.97e-02	1.00e+00	2.197	2	12	339
GO:0051087	chaperone binding	7.33e-02	1.00e+00	3.719	1	6	59
GO:0045216	cell-cell junction organization	7.33e-02	1.00e+00	3.719	1	2	59
GO:0042995	cell projection	7.81e-02	1.00e+00	3.625	1	6	63
GO:0030141	secretory granule	8.28e-02	1.00e+00	3.536	1	2	67
GO:0003697	single-stranded DNA binding	8.52e-02	1.00e+00	3.494	1	9	69
GO:0034329	cell junction assembly	8.75e-02	1.00e+00	3.452	1	1	71
GO:0055086	nucleobase-containing small molecule metabolic process	8.99e-02	1.00e+00	3.412	1	5	73
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	9.34e-02	1.00e+00	3.354	1	3	76
GO:0008584	male gonad development	9.46e-02	1.00e+00	3.335	1	2	77
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	9.46e-02	1.00e+00	3.335	1	6	77
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	9.46e-02	1.00e+00	3.335	1	5	77
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	9.81e-02	1.00e+00	3.280	1	2	80
GO:0051301	cell division	9.93e-02	1.00e+00	3.262	1	6	81
GO:0050821	protein stabilization	1.11e-01	1.00e+00	3.094	1	2	91
GO:0016363	nuclear matrix	1.12e-01	1.00e+00	3.079	1	11	92
GO:0006928	cellular component movement	1.12e-01	1.00e+00	3.079	1	7	92
GO:0051082	unfolded protein binding	1.15e-01	1.00e+00	3.032	1	6	95
GO:0006364	rRNA processing	1.17e-01	1.00e+00	3.017	1	5	96
GO:0007010	cytoskeleton organization	1.17e-01	1.00e+00	3.017	1	2	96
GO:0071456	cellular response to hypoxia	1.19e-01	1.00e+00	2.987	1	4	98
GO:0055114	oxidation-reduction process	1.26e-01	1.00e+00	1.692	2	11	481
GO:0008360	regulation of cell shape	1.28e-01	1.00e+00	2.874	1	1	106
GO:0014069	postsynaptic density	1.28e-01	1.00e+00	2.874	1	1	106
GO:0015630	microtubule cytoskeleton	1.35e-01	1.00e+00	2.795	1	5	112
GO:0030529	ribonucleoprotein complex	1.37e-01	1.00e+00	2.769	1	8	114
GO:0072562	blood microparticle	1.39e-01	1.00e+00	2.744	1	4	116
GO:0005635	nuclear envelope	1.39e-01	1.00e+00	2.744	1	6	116
GO:0044237	cellular metabolic process	1.41e-01	1.00e+00	2.719	1	3	118
GO:0006325	chromatin organization	1.47e-01	1.00e+00	2.660	1	4	123
GO:0005739	mitochondrion	1.48e-01	1.00e+00	1.156	3	24	1046
GO:0007219	Notch signaling pathway	1.49e-01	1.00e+00	2.636	1	4	125
GO:0006260	DNA replication	1.49e-01	1.00e+00	2.636	1	12	125
GO:0005506	iron ion binding	1.51e-01	1.00e+00	2.613	1	3	127
GO:0006511	ubiquitin-dependent protein catabolic process	1.51e-01	1.00e+00	2.613	1	5	127
GO:0006413	translational initiation	1.56e-01	1.00e+00	2.569	1	12	131
GO:0016477	cell migration	1.56e-01	1.00e+00	2.569	1	6	131
GO:0009615	response to virus	1.57e-01	1.00e+00	2.558	1	6	132
GO:0044822	poly(A) RNA binding	1.58e-01	1.00e+00	1.113	3	50	1078
GO:0000790	nuclear chromatin	1.58e-01	1.00e+00	2.547	1	7	133
GO:0000086	G2/M transition of mitotic cell cycle	1.62e-01	1.00e+00	2.504	1	7	137
GO:0061024	membrane organization	1.72e-01	1.00e+00	2.412	1	5	146
GO:0006457	protein folding	1.75e-01	1.00e+00	2.383	1	8	149
GO:0005769	early endosome	1.85e-01	1.00e+00	2.298	1	2	158
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.95e-01	1.00e+00	2.210	1	5	168
GO:0006397	mRNA processing	1.96e-01	1.00e+00	2.201	1	3	169
GO:0030424	axon	2.00e-01	1.00e+00	2.176	1	3	172
GO:0016607	nuclear speck	2.03e-01	1.00e+00	2.151	1	4	175
GO:0007049	cell cycle	2.05e-01	1.00e+00	2.135	1	3	177
GO:0003714	transcription corepressor activity	2.07e-01	1.00e+00	2.118	1	7	179
GO:0031625	ubiquitin protein ligase binding	2.08e-01	1.00e+00	2.110	1	13	180
GO:0032403	protein complex binding	2.13e-01	1.00e+00	2.071	1	7	185
GO:0003924	GTPase activity	2.31e-01	1.00e+00	1.937	1	9	203
GO:0005737	cytoplasm	2.34e-01	1.00e+00	0.452	7	98	3976
GO:0006184	GTP catabolic process	2.48e-01	1.00e+00	1.821	1	9	220
GO:0008380	RNA splicing	2.60e-01	1.00e+00	1.744	1	13	232
GO:0003713	transcription coactivator activity	2.67e-01	1.00e+00	1.701	1	10	239
GO:0043025	neuronal cell body	2.81e-01	1.00e+00	1.613	1	4	254
GO:0004842	ubiquitin-protein transferase activity	2.83e-01	1.00e+00	1.602	1	4	256
GO:0006281	DNA repair	2.90e-01	1.00e+00	1.558	1	22	264
GO:0005975	carbohydrate metabolic process	2.99e-01	1.00e+00	1.504	1	5	274
GO:0043065	positive regulation of apoptotic process	2.99e-01	1.00e+00	1.504	1	8	274
GO:0016567	protein ubiquitination	3.22e-01	1.00e+00	1.378	1	5	299
GO:0005743	mitochondrial inner membrane	3.23e-01	1.00e+00	1.373	1	5	300
GO:0005856	cytoskeleton	3.33e-01	1.00e+00	1.321	1	8	311
GO:0019901	protein kinase binding	3.40e-01	1.00e+00	1.280	1	21	320
GO:0007411	axon guidance	3.46e-01	1.00e+00	1.249	1	9	327
GO:0005525	GTP binding	3.47e-01	1.00e+00	1.245	1	11	328
GO:0003723	RNA binding	3.70e-01	1.00e+00	1.130	1	19	355
GO:0005615	extracellular space	3.76e-01	1.00e+00	0.622	2	17	1010
GO:0005925	focal adhesion	3.82e-01	1.00e+00	1.071	1	18	370
GO:0009986	cell surface	4.23e-01	1.00e+00	0.881	1	9	422
GO:0007596	blood coagulation	4.54e-01	1.00e+00	0.744	1	14	464
GO:0044267	cellular protein metabolic process	4.76e-01	1.00e+00	0.651	1	24	495
GO:0045087	innate immune response	5.54e-01	1.00e+00	0.335	1	20	616
GO:0008270	zinc ion binding	7.58e-01	1.00e+00	-0.457	1	12	1067
GO:0005886	plasma membrane	9.82e-01	1.00e+00	-1.866	1	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-6240

Interacting subnets

Genes (21)

Interactions (71)

Related GO terms (227)