meta-int-snw-2027

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-2027 wolf-screen-ratio-mammosphere-adherent 0.968 8.21e-17 1.18e-03 2.34e-02 10 8
reg-snw-5925 wolf-screen-ratio-mammosphere-adherent 0.802 2.42e-06 4.82e-03 8.69e-03 8 5
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-2027 subnetwork

Genes (22)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PPCS 79717 31-0.5690.8022-Yes
RBX1 9978 1151.1850.934148Yes-
PPIE 10450 310.5670.80241--
PSMB7 5695 1180.9820.93490Yes-
HNRNPC 3183 1081.8120.973181Yes-
TREX1 11277 51-0.0510.88291Yes-
OGDH 4967 720.8470.802126Yes-
TFRC 7037 310.7300.80217--
RPSA 3921 1201.3271.151152Yes-
PGD 5226 891.2011.106152Yes-
RPA2 6118 961.2501.15176Yes-
CAD 790 910.8070.973400--
RB1 5925 31-0.1020.802351--
EEF2 1938 640.8901.043301Yes-
ENO3 2027 3-0.1030.96873--
NAA10 8260 50.6680.983136Yes-
PSMB2 5690 1160.8770.956169Yes-
PSMD11 5717 1241.0951.106218Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
RAN 5901 890.6320.899258Yes-

Interactions (57)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
RB1 5925 PPCS 79717 pd > reg.pazar.txt: no annot
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
RB1 5925 RPA2 6118 pd > reg.pazar.txt: no annot
PGD 5226 RAN 5901 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PGD 5226 RB1 5925 pd < reg.pazar.txt: no annot
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
RBX1 9978 PPIE 10450 pd <> reg.ITFP.txt: no annot
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RAN 5901 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
RPSA 3921 NAA10 8260 pp -- int.I2D: IntAct_Yeast
OGDH 4967 RB1 5925 pd < reg.ITFP.txt: no annot
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACTB 60 NAA10 8260 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
CAD 790 NAA10 8260 pp -- int.I2D: IntAct_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
ENO3 2027 NAA10 8260 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
CAD 790 ENO3 2027 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ACTB 60 ENO3 2027 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
EEF2 1938 ENO3 2027 pp -- int.I2D: YeastLow
PSMB7 5695 PPIE 10450 pd < reg.ITFP.txt: no annot
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
RB1 5925 TFRC 7037 pd > reg.ITFP.txt: no annot
OGDH 4967 RAN 5901 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RB1 5925 PPIE 10450 pd > reg.pazar.txt: no annot
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast

Related GO terms (390)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016032viral process1.51e-082.46e-043.628955540
GO:0000082G1/S transition of mitotic cell cycle3.60e-085.88e-044.891633150
GO:0070062extracellular vesicular exosome3.67e-085.99e-042.14515982516
GO:0005654nucleoplasm4.19e-086.83e-042.89811831095
GO:0005829cytosol4.72e-087.70e-042.119151252562
GO:0006521regulation of cellular amino acid metabolic process5.47e-078.93e-035.89142150
GO:0000502proteasome complex1.00e-061.63e-025.67742258
GO:0010467gene expression1.47e-062.39e-023.149858669
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.59e-062.59e-025.51342465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.59e-062.59e-025.51342265
GO:0005839proteasome core complex1.71e-062.79e-026.95031118
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.14e-063.49e-025.40642470
GO:0004298threonine-type endopeptidase activity2.39e-063.90e-026.79831120
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.53e-064.14e-025.34542373
GO:0044281small molecule metabolic process2.55e-064.16e-022.51810571295
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.68e-064.37e-025.32642474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.14e-065.13e-025.26842377
GO:0034641cellular nitrogen compound metabolic process3.21e-065.25e-024.389525177
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.48e-065.68e-025.23142579
GO:0016020membrane4.68e-067.64e-022.22511801746
GO:0002474antigen processing and presentation of peptide antigen via MHC class I6.97e-061.14e-014.98042394
GO:0016071mRNA metabolic process9.92e-061.62e-014.056534223
GO:0000278mitotic cell cycle1.08e-051.77e-013.483652398
GO:0000209protein polyubiquitination1.61e-052.62e-014.677421116
GO:0016070RNA metabolic process1.63e-052.65e-013.909534247
GO:0005634nucleus3.61e-055.88e-011.298161314828
GO:0042981regulation of apoptotic process4.52e-057.38e-014.297426151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.04e-058.23e-015.3653554
GO:0035267NuA4 histone acetyltransferase complex1.56e-041.00e+006.7282414
GO:0006259DNA metabolic process2.93e-041.00e+006.2872319
GO:0006298mismatch repair3.25e-041.00e+006.2132620
GO:0006281DNA repair3.89e-041.00e+003.491422264
GO:0042802identical protein binding4.16e-041.00e+002.917518491
GO:0043044ATP-dependent chromatin remodeling4.31e-041.00e+006.0112423
GO:0030529ribonucleoprotein complex4.64e-041.00e+004.28738114
GO:0043022ribosome binding6.42e-041.00e+005.7282328
GO:0031492nucleosomal DNA binding6.42e-041.00e+005.7282428
GO:0005515protein binding8.57e-041.00e+000.954161726127
GO:0006457protein folding1.01e-031.00e+003.90138149
GO:0050681androgen receptor binding1.18e-031.00e+005.2872438
GO:0006096glycolytic process1.25e-031.00e+005.2502439
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity1.35e-031.00e+009.535111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity1.35e-031.00e+009.535111
GO:0070335aspartate binding1.35e-031.00e+009.535111
GO:0032558adenyl deoxyribonucleotide binding1.35e-031.00e+009.535111
GO:0090230regulation of centromere complex assembly1.35e-031.00e+009.535111
GO:0004151dihydroorotase activity1.35e-031.00e+009.535111
GO:0004632phosphopantothenate--cysteine ligase activity1.35e-031.00e+009.535111
GO:0019521D-gluconate metabolic process1.35e-031.00e+009.535111
GO:0004070aspartate carbamoyltransferase activity1.35e-031.00e+009.535111
GO:0030521androgen receptor signaling pathway1.38e-031.00e+005.1772241
GO:0031625ubiquitin protein ligase binding1.74e-031.00e+003.628313180
GO:0003684damaged DNA binding2.12e-031.00e+004.86321151
GO:0044822poly(A) RNA binding2.44e-031.00e+002.0466501078
GO:0043066negative regulation of apoptotic process2.45e-031.00e+002.777430433
GO:0045252oxoglutarate dehydrogenase complex2.69e-031.00e+008.535122
GO:0097286iron ion import2.69e-031.00e+008.535112
GO:0006407rRNA export from nucleus2.69e-031.00e+008.535112
GO:0061034olfactory bulb mitral cell layer development2.69e-031.00e+008.535112
GO:00082963'-5'-exodeoxyribonuclease activity2.69e-031.00e+008.535112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.69e-031.00e+008.535112
GO:0004998transferrin receptor activity2.69e-031.00e+008.535112
GO:0019322pentose biosynthetic process2.69e-031.00e+008.535112
GO:0031134sister chromatid biorientation2.69e-031.00e+008.535112
GO:0005055laminin receptor activity2.69e-031.00e+008.535112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis2.69e-031.00e+008.535122
GO:0070409carbamoyl phosphate biosynthetic process2.69e-031.00e+008.535112
GO:0006310DNA recombination3.64e-031.00e+004.4692467
GO:0006338chromatin remodeling3.74e-031.00e+004.4482468
GO:0003697single-stranded DNA binding3.85e-031.00e+004.4262969
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity4.04e-031.00e+007.950113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb4.04e-031.00e+007.950113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity4.04e-031.00e+007.950113
GO:0071459protein localization to chromosome, centromeric region4.04e-031.00e+007.950113
GO:0071899negative regulation of estrogen receptor binding4.04e-031.00e+007.950113
GO:0071733transcriptional activation by promoter-enhancer looping4.04e-031.00e+007.950113
GO:0000056ribosomal small subunit export from nucleus4.04e-031.00e+007.950113
GO:0009051pentose-phosphate shunt, oxidative branch4.04e-031.00e+007.950113
GO:0044205'de novo' UMP biosynthetic process4.04e-031.00e+007.950113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle4.04e-031.00e+007.950113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process4.04e-031.00e+007.950113
GO:0000785chromatin4.30e-031.00e+004.3452573
GO:0071013catalytic step 2 spliceosome5.02e-031.00e+004.2312779
GO:0005730nucleolus5.19e-031.00e+001.6257701684
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)5.38e-031.00e+007.535114
GO:003068690S preribosome5.38e-031.00e+007.535114
GO:0071922regulation of cohesin localization to chromatin5.38e-031.00e+007.535114
GO:0019788NEDD8 ligase activity5.38e-031.00e+007.535114
GO:0000015phosphopyruvate hydratase complex5.38e-031.00e+007.535124
GO:0004634phosphopyruvate hydratase activity5.38e-031.00e+007.535124
GO:0043141ATP-dependent 5'-3' DNA helicase activity5.38e-031.00e+007.535114
GO:0006104succinyl-CoA metabolic process5.38e-031.00e+007.535114
GO:0006543glutamine catabolic process5.38e-031.00e+007.535114
GO:0031467Cul7-RING ubiquitin ligase complex5.38e-031.00e+007.535114
GO:0043550regulation of lipid kinase activity5.38e-031.00e+007.535114
GO:0000055ribosomal large subunit export from nucleus5.38e-031.00e+007.535114
GO:0035189Rb-E2F complex5.38e-031.00e+007.535114
GO:0034349glial cell apoptotic process5.38e-031.00e+007.535114
GO:0034088maintenance of mitotic sister chromatid cohesion5.38e-031.00e+007.535114
GO:0008853exodeoxyribonuclease III activity5.38e-031.00e+007.535114
GO:0006915apoptotic process6.56e-031.00e+002.378434571
GO:0051414response to cortisol6.72e-031.00e+007.213115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex6.72e-031.00e+007.213125
GO:0032407MutSalpha complex binding6.72e-031.00e+007.213115
GO:2000001regulation of DNA damage checkpoint6.72e-031.00e+007.213115
GO:0031415NatA complex6.72e-031.00e+007.213115
GO:0031461cullin-RING ubiquitin ligase complex6.72e-031.00e+007.213115
GO:0071169establishment of protein localization to chromatin6.72e-031.00e+007.213115
GO:0043248proteasome assembly6.72e-031.00e+007.213115
GO:0006323DNA packaging6.72e-031.00e+007.213115
GO:0048667cell morphogenesis involved in neuron differentiation6.72e-031.00e+007.213115
GO:0030891VCB complex6.72e-031.00e+007.213125
GO:0000730DNA recombinase assembly6.72e-031.00e+007.213135
GO:0006734NADH metabolic process6.72e-031.00e+007.213115
GO:0030976thiamine pyrophosphate binding6.72e-031.00e+007.213115
GO:0016363nuclear matrix6.75e-031.00e+004.01121192
GO:0016605PML body6.75e-031.00e+004.0112592
GO:0042470melanosome6.75e-031.00e+004.01121092
GO:0006414translational elongation6.89e-031.00e+003.99621193
GO:0043234protein complex7.31e-031.00e+002.891317300
GO:0043353enucleate erythrocyte differentiation8.06e-031.00e+006.950116
GO:0009108coenzyme biosynthetic process8.06e-031.00e+006.950116
GO:0006474N-terminal protein amino acid acetylation8.06e-031.00e+006.950116
GO:0045842positive regulation of mitotic metaphase/anaphase transition8.06e-031.00e+006.950116
GO:0021860pyramidal neuron development8.06e-031.00e+006.950116
GO:0031466Cul5-RING ubiquitin ligase complex8.06e-031.00e+006.950116
GO:0021695cerebellar cortex development8.06e-031.00e+006.950116
GO:0030957Tat protein binding8.06e-031.00e+006.950146
GO:0046134pyrimidine nucleoside biosynthetic process8.06e-031.00e+006.950116
GO:0032405MutLalpha complex binding8.06e-031.00e+006.950126
GO:0000028ribosomal small subunit assembly9.40e-031.00e+006.728117
GO:0004596peptide alpha-N-acetyltransferase activity9.40e-031.00e+006.728117
GO:0031462Cul2-RING ubiquitin ligase complex9.40e-031.00e+006.728127
GO:0006475internal protein amino acid acetylation9.40e-031.00e+006.728117
GO:0016018cyclosporin A binding9.40e-031.00e+006.728117
GO:0019058viral life cycle1.04e-021.00e+003.690210115
GO:0072562blood microparticle1.05e-021.00e+003.67724116
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.07e-021.00e+006.535128
GO:0070688MLL5-L complex1.07e-021.00e+006.535118
GO:0006554lysine catabolic process1.07e-021.00e+006.535128
GO:0000812Swr1 complex1.07e-021.00e+006.535138
GO:0045116protein neddylation1.07e-021.00e+006.535128
GO:0006325chromatin organization1.18e-021.00e+003.59224123
GO:0014075response to amine1.21e-021.00e+006.365119
GO:0015937coenzyme A biosynthetic process1.21e-021.00e+006.365119
GO:0008494translation activator activity1.21e-021.00e+006.365119
GO:0097284hepatocyte apoptotic process1.21e-021.00e+006.365129
GO:0006228UTP biosynthetic process1.21e-021.00e+006.365119
GO:0000075cell cycle checkpoint1.21e-021.00e+006.365129
GO:0031000response to caffeine1.21e-021.00e+006.365129
GO:0006260DNA replication1.22e-021.00e+003.569212125
GO:0016407acetyltransferase activity1.34e-021.00e+006.2131110
GO:0008080N-acetyltransferase activity1.34e-021.00e+006.2131110
GO:0015939pantothenate metabolic process1.34e-021.00e+006.2131110
GO:0021756striatum development1.34e-021.00e+006.2131110
GO:0000790nuclear chromatin1.37e-021.00e+003.48027133
GO:0006098pentose-phosphate shunt1.47e-021.00e+006.0761311
GO:0010569regulation of double-strand break repair via homologous recombination1.47e-021.00e+006.0761111
GO:0031571mitotic G1 DNA damage checkpoint1.47e-021.00e+006.0761311
GO:0042551neuron maturation1.47e-021.00e+006.0761211
GO:0045651positive regulation of macrophage differentiation1.47e-021.00e+006.0761211
GO:0045120pronucleus1.47e-021.00e+006.0761111
GO:0035458cellular response to interferon-beta1.47e-021.00e+006.0761211
GO:0043403skeletal muscle tissue regeneration1.47e-021.00e+006.0761111
GO:00709353'-UTR-mediated mRNA stabilization1.61e-021.00e+005.9501212
GO:0043968histone H2A acetylation1.61e-021.00e+005.9501312
GO:0051146striated muscle cell differentiation1.61e-021.00e+005.9501112
GO:0021794thalamus development1.61e-021.00e+005.9501112
GO:0005838proteasome regulatory particle1.61e-021.00e+005.9501712
GO:0032479regulation of type I interferon production1.74e-021.00e+005.8351213
GO:0005662DNA replication factor A complex1.74e-021.00e+005.8351313
GO:0045780positive regulation of bone resorption1.74e-021.00e+005.8351113
GO:0000738DNA catabolic process, exonucleolytic1.74e-021.00e+005.8351213
GO:0008266poly(U) RNA binding1.74e-021.00e+005.8351113
GO:0031011Ino80 complex1.87e-021.00e+005.7281314
GO:0045445myoblast differentiation2.00e-021.00e+005.6281215
GO:0035066positive regulation of histone acetylation2.00e-021.00e+005.6281115
GO:0016514SWI/SNF complex2.00e-021.00e+005.6281315
GO:0000398mRNA splicing, via spliceosome2.06e-021.00e+003.169212165
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding2.13e-021.00e+003.14325168
GO:0050998nitric-oxide synthase binding2.14e-021.00e+005.5351116
GO:00061032-oxoglutarate metabolic process2.14e-021.00e+005.5351116
GO:00084083'-5' exonuclease activity2.14e-021.00e+005.5351216
GO:0010243response to organonitrogen compound2.27e-021.00e+005.4481217
GO:0003746translation elongation factor activity2.27e-021.00e+005.4481317
GO:0045070positive regulation of viral genome replication2.27e-021.00e+005.4481117
GO:0075733intracellular transport of virus2.27e-021.00e+005.4481217
GO:0022624proteasome accessory complex2.27e-021.00e+005.4481917
GO:0071392cellular response to estradiol stimulus2.40e-021.00e+005.3651118
GO:0006541glutamine metabolic process2.40e-021.00e+005.3651118
GO:0035861site of double-strand break2.40e-021.00e+005.3651118
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.53e-021.00e+005.2871119
GO:0048863stem cell differentiation2.53e-021.00e+005.2871119
GO:0003678DNA helicase activity2.53e-021.00e+005.2871319
GO:2000134negative regulation of G1/S transition of mitotic cell cycle2.66e-021.00e+005.2131220
GO:0005719nuclear euchromatin2.66e-021.00e+005.2131220
GO:0044267cellular protein metabolic process2.78e-021.00e+002.169324495
GO:0000718nucleotide-excision repair, DNA damage removal2.79e-021.00e+005.1431521
GO:0071364cellular response to epidermal growth factor stimulus2.79e-021.00e+005.1431121
GO:0030316osteoclast differentiation2.93e-021.00e+005.0761222
GO:0006297nucleotide-excision repair, DNA gap filling2.93e-021.00e+005.0761522
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle2.93e-021.00e+005.0761322
GO:0033574response to testosterone2.93e-021.00e+005.0761222
GO:0032201telomere maintenance via semi-conservative replication2.93e-021.00e+005.0761722
GO:0030863cortical cytoskeleton2.93e-021.00e+005.0761122
GO:0036464cytoplasmic ribonucleoprotein granule2.93e-021.00e+005.0761422
GO:0007052mitotic spindle organization2.93e-021.00e+005.0761222
GO:0003924GTPase activity3.02e-021.00e+002.87029203
GO:0031463Cul3-RING ubiquitin ligase complex3.06e-021.00e+005.0111223
GO:0043236laminin binding3.06e-021.00e+005.0111123
GO:0006513protein monoubiquitination3.06e-021.00e+005.0111123
GO:0045879negative regulation of smoothened signaling pathway3.06e-021.00e+005.0111123
GO:0006206pyrimidine nucleobase metabolic process3.19e-021.00e+004.9501224
GO:0006611protein export from nucleus3.32e-021.00e+004.8911425
GO:0005844polysome3.32e-021.00e+004.8911425
GO:0017144drug metabolic process3.32e-021.00e+004.8911125
GO:0000722telomere maintenance via recombination3.45e-021.00e+004.8351726
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia3.45e-021.00e+004.8351226
GO:0006184GTP catabolic process3.50e-021.00e+002.75429220
GO:0004003ATP-dependent DNA helicase activity3.58e-021.00e+004.7801327
GO:0048565digestive tract development3.58e-021.00e+004.7801127
GO:0071339MLL1 complex3.58e-021.00e+004.7801327
GO:0005622intracellular3.68e-021.00e+002.71525226
GO:0043967histone H4 acetylation3.71e-021.00e+004.7281328
GO:0019894kinesin binding3.71e-021.00e+004.7281128
GO:0006099tricarboxylic acid cycle3.84e-021.00e+004.6771329
GO:0019005SCF ubiquitin ligase complex3.84e-021.00e+004.6771129
GO:0003730mRNA 3'-UTR binding3.84e-021.00e+004.6771229
GO:0006412translation3.95e-021.00e+002.658215235
GO:0007346regulation of mitotic cell cycle3.97e-021.00e+004.6281330
GO:0003713transcription coactivator activity4.07e-021.00e+002.634210239
GO:0006271DNA strand elongation involved in DNA replication4.10e-021.00e+004.5811931
GO:0007093mitotic cell cycle checkpoint4.10e-021.00e+004.5811231
GO:0050661NADP binding4.23e-021.00e+004.5351132
GO:0051219phosphoprotein binding4.23e-021.00e+004.5351332
GO:0034644cellular response to UV4.23e-021.00e+004.5351532
GO:0033572transferrin transport4.23e-021.00e+004.5351632
GO:0031072heat shock protein binding4.36e-021.00e+004.4911233
GO:0000413protein peptidyl-prolyl isomerization4.49e-021.00e+004.4481134
GO:0003755peptidyl-prolyl cis-trans isomerase activity4.49e-021.00e+004.4481134
GO:0034332adherens junction organization4.74e-021.00e+004.3651136
GO:0051402neuron apoptotic process4.74e-021.00e+004.3651236
GO:0001895retina homeostasis4.74e-021.00e+004.3651136
GO:0001102RNA polymerase II activating transcription factor binding4.87e-021.00e+004.3261437
GO:0051084'de novo' posttranslational protein folding4.87e-021.00e+004.3261437
GO:0018107peptidyl-threonine phosphorylation4.87e-021.00e+004.3261137
GO:0070527platelet aggregation5.00e-021.00e+004.2871238
GO:0021766hippocampus development5.13e-021.00e+004.2501439
GO:0031490chromatin DNA binding5.13e-021.00e+004.2501239
GO:0006284base-excision repair5.13e-021.00e+004.2501739
GO:0022627cytosolic small ribosomal subunit5.13e-021.00e+004.2501339
GO:0032092positive regulation of protein binding5.13e-021.00e+004.2501339
GO:0007595lactation5.13e-021.00e+004.2501239
GO:0000166nucleotide binding5.14e-021.00e+002.44826272
GO:0005975carbohydrate metabolic process5.20e-021.00e+002.43725274
GO:0000781chromosome, telomeric region5.26e-021.00e+004.2131240
GO:0043195terminal bouton5.39e-021.00e+004.1771141
GO:0035914skeletal muscle cell differentiation5.51e-021.00e+004.1431142
GO:0032508DNA duplex unwinding5.51e-021.00e+004.1431442
GO:0014070response to organic cyclic compound5.64e-021.00e+004.1091343
GO:0019899enzyme binding5.69e-021.00e+002.365211288
GO:0007286spermatid development5.77e-021.00e+004.0761144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding5.77e-021.00e+004.0761244
GO:0006094gluconeogenesis5.90e-021.00e+004.0431345
GO:0021762substantia nigra development6.02e-021.00e+004.0111146
GO:0001047core promoter binding6.02e-021.00e+004.0111246
GO:0006283transcription-coupled nucleotide-excision repair6.02e-021.00e+004.0111846
GO:0045727positive regulation of translation6.02e-021.00e+004.0111446
GO:0019003GDP binding6.28e-021.00e+003.9501248
GO:0031100organ regeneration6.53e-021.00e+003.8911450
GO:0035690cellular response to drug6.53e-021.00e+003.8911250
GO:0006091generation of precursor metabolites and energy6.66e-021.00e+003.8631351
GO:0005905coated pit6.66e-021.00e+003.8631251
GO:0040008regulation of growth6.66e-021.00e+003.8631351
GO:0019901protein kinase binding6.84e-021.00e+002.213221320
GO:0003725double-stranded RNA binding7.04e-021.00e+003.7801654
GO:0090305nucleic acid phosphodiester bond hydrolysis7.04e-021.00e+003.7801254
GO:0019900kinase binding7.04e-021.00e+003.7801154
GO:0050680negative regulation of epithelial cell proliferation7.04e-021.00e+003.7801154
GO:0005525GTP binding7.14e-021.00e+002.177211328
GO:0006879cellular iron ion homeostasis7.41e-021.00e+003.7021557
GO:0000724double-strand break repair via homologous recombination7.41e-021.00e+003.7021657
GO:0002244hematopoietic progenitor cell differentiation7.54e-021.00e+003.6771158
GO:0051087chaperone binding7.66e-021.00e+003.6521659
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity7.66e-021.00e+003.6521459
GO:0045216cell-cell junction organization7.66e-021.00e+003.6521259
GO:0000723telomere maintenance7.66e-021.00e+003.6521859
GO:0005643nuclear pore7.66e-021.00e+003.6521459
GO:0031966mitochondrial membrane7.66e-021.00e+003.6521159
GO:0032481positive regulation of type I interferon production7.91e-021.00e+003.6041661
GO:0006302double-strand break repair8.04e-021.00e+003.5811862
GO:0019903protein phosphatase binding8.16e-021.00e+003.5581463
GO:0042995cell projection8.16e-021.00e+003.5581663
GO:0003723RNA binding8.19e-021.00e+002.063219355
GO:0006469negative regulation of protein kinase activity8.41e-021.00e+003.5131265
GO:0001558regulation of cell growth8.53e-021.00e+003.4911466
GO:0006289nucleotide-excision repair8.90e-021.00e+003.42611269
GO:0034329cell junction assembly9.15e-021.00e+003.3851171
GO:0055037recycling endosome9.40e-021.00e+003.3451273
GO:0055086nucleobase-containing small molecule metabolic process9.40e-021.00e+003.3451573
GO:0006767water-soluble vitamin metabolic process9.64e-021.00e+003.3061375
GO:0007265Ras protein signal transduction9.64e-021.00e+003.3061375
GO:0031175neuron projection development9.64e-021.00e+003.3061175
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process9.76e-021.00e+003.2871376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis9.89e-021.00e+003.2681577
GO:0006766vitamin metabolic process1.00e-011.00e+003.2501378
GO:0007565female pregnancy1.03e-011.00e+003.2131280
GO:0019083viral transcription1.04e-011.00e+003.1951881
GO:0001889liver development1.05e-011.00e+003.1771382
GO:0005681spliceosomal complex1.06e-011.00e+003.1601383
GO:0047485protein N-terminus binding1.10e-011.00e+003.1091486
GO:0006898receptor-mediated endocytosis1.10e-011.00e+003.1091286
GO:0006415translational termination1.11e-011.00e+003.0921887
GO:0003690double-stranded DNA binding1.16e-011.00e+003.0271491
GO:0006928cellular component movement1.17e-011.00e+003.0111792
GO:0005200structural constituent of cytoskeleton1.18e-011.00e+002.9961793
GO:0051082unfolded protein binding1.21e-011.00e+002.9651695
GO:0001649osteoblast differentiation1.21e-011.00e+002.9651695
GO:0071456cellular response to hypoxia1.24e-011.00e+002.9201498
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.31e-011.00e+002.83518104
GO:0014069postsynaptic density1.34e-011.00e+002.80711106
GO:0016023cytoplasmic membrane-bounded vesicle1.35e-011.00e+002.79413107
GO:0045893positive regulation of transcription, DNA-templated1.39e-011.00e+001.607217487
GO:0042127regulation of cell proliferation1.39e-011.00e+002.74114111
GO:0015630microtubule cytoskeleton1.41e-011.00e+002.72815112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.43e-011.00e+002.702110114
GO:0005819spindle1.43e-011.00e+002.70217114
GO:0005635nuclear envelope1.45e-011.00e+002.67716116
GO:0044237cellular metabolic process1.48e-011.00e+002.65213118
GO:0006006glucose metabolic process1.49e-011.00e+002.64014119
GO:0005615extracellular space1.52e-011.00e+001.1403171010
GO:0007568aging1.53e-011.00e+002.59213123
GO:0007219Notch signaling pathway1.56e-011.00e+002.56914125
GO:0007050cell cycle arrest1.57e-011.00e+002.55817126
GO:0006511ubiquitin-dependent protein catabolic process1.58e-011.00e+002.54615127
GO:0006413translational initiation1.63e-011.00e+002.502112131
GO:0031982vesicle1.66e-011.00e+002.469110134
GO:0003735structural constituent of ribosome1.74e-011.00e+002.39518141
GO:0007507heart development1.74e-011.00e+002.39515141
GO:0016887ATPase activity1.77e-011.00e+002.36517144
GO:0061024membrane organization1.79e-011.00e+002.34515146
GO:0010628positive regulation of gene expression1.83e-011.00e+002.31614149
GO:0046777protein autophosphorylation1.93e-011.00e+002.23113158
GO:0042803protein homodimerization activity2.01e-011.00e+001.266211617
GO:0045087innate immune response2.01e-011.00e+001.268220616
GO:0030424axon2.08e-011.00e+002.10913172
GO:0000287magnesium ion binding2.10e-011.00e+002.09215174
GO:0005768endosome2.10e-011.00e+002.09215174
GO:0004672protein kinase activity2.14e-011.00e+002.05912178
GO:0019904protein domain specific binding2.18e-011.00e+002.03516181
GO:0009897external side of plasma membrane2.20e-011.00e+002.01914183
GO:0032403protein complex binding2.22e-011.00e+002.00417185
GO:0007067mitotic nuclear division2.69e-011.00e+001.683113231
GO:0008380RNA splicing2.70e-011.00e+001.677113232
GO:0005759mitochondrial matrix2.71e-011.00e+001.671112233
GO:0005524ATP binding2.74e-011.00e+000.7173461354
GO:0008134transcription factor binding2.84e-011.00e+001.59218246
GO:0043025neuronal cell body2.92e-011.00e+001.54614254
GO:0004842ubiquitin-protein transferase activity2.94e-011.00e+001.53514256
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.99e-011.00e+000.871219811
GO:0042493response to drug3.24e-011.00e+001.365111288
GO:0007264small GTPase mediated signal transduction3.26e-011.00e+001.35513290
GO:0016567protein ubiquitination3.34e-011.00e+001.31115299
GO:0006200ATP catabolic process3.38e-011.00e+001.292114303
GO:0005856cytoskeleton3.45e-011.00e+001.25418311
GO:0007411axon guidance3.60e-011.00e+001.18219327
GO:0043231intracellular membrane-bounded organelle3.64e-011.00e+001.16018332
GO:0003682chromatin binding3.66e-011.00e+001.151112334
GO:0005925focal adhesion3.96e-011.00e+001.004118370
GO:0007155cell adhesion4.08e-011.00e+000.95018384
GO:0046982protein heterodimerization activity4.20e-011.00e+000.895111399
GO:0008270zinc ion binding4.26e-011.00e+000.4762121067
GO:0009986cell surface4.38e-011.00e+000.81419422
GO:0045892negative regulation of transcription, DNA-templated4.40e-011.00e+000.807114424
GO:0005737cytoplasm4.55e-011.00e+000.1636983976
GO:0007596blood coagulation4.70e-011.00e+000.677114464
GO:0055114oxidation-reduction process4.82e-011.00e+000.625111481
GO:0055085transmembrane transport5.06e-011.00e+000.52918514
GO:0048471perinuclear region of cytoplasm5.12e-011.00e+000.504112523
GO:0005789endoplasmic reticulum membrane5.83e-011.00e+000.222110636
GO:0046872metal ion binding6.00e-011.00e+000.0182241465
GO:0006351transcription, DNA-templated6.44e-011.00e+00-0.0952251585
GO:0003700sequence-specific DNA binding transcription factor activity6.44e-011.00e+00-0.012111748
GO:0007165signal transduction7.33e-011.00e+00-0.357117950
GO:0005887integral component of plasma membrane7.37e-011.00e+00-0.37317961
GO:0005886plasma membrane7.62e-011.00e+00-0.3493382834
GO:0005739mitochondrion7.67e-011.00e+00-0.4961241046
GO:0005576extracellular region7.68e-011.00e+00-0.500191049
GO:0006355regulation of transcription, DNA-templated7.86e-011.00e+00-0.5741171104
GO:0003677DNA binding8.51e-011.00e+00-0.8651261351