meta-int-snw-10393

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-56655	wolf-screen-ratio-mammosphere-adherent	0.828	9.29e-07	2.91e-03	5.53e-03	8	7
int-snw-10393	wolf-screen-ratio-mammosphere-adherent	0.971	6.41e-17	1.11e-03	2.23e-02	12	12
reg-snw-5925	wolf-screen-ratio-mammosphere-adherent	0.802	2.42e-06	4.82e-03	8.69e-03	8	5

wolf-screen-ratio-mammosphere-adherent-meta-int-snw-10393 subnetwork

Genes (22)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PPCS	79717	31	-0.569	0.802	2	-	Yes
UBA1	7317	6	0.555	0.971	207	Yes	-
PSMA2	5683	112	1.093	1.106	108	Yes	-
RBX1	9978	115	1.185	0.934	148	Yes	-
PPIE	10450	31	0.567	0.802	41	-	-
PSMB7	5695	118	0.982	0.934	90	Yes	-
VARS	7407	86	0.549	1.002	204	Yes	-
OGDH	4967	72	0.847	0.802	126	Yes	-
POLE4	56655	63	0.177	0.828	56	-	-
TFRC	7037	31	0.730	0.802	17	-	-
RPSA	3921	120	1.327	1.151	152	Yes	-
PSMB3	5691	64	0.668	0.901	19	Yes	-
PGD	5226	89	1.201	1.106	152	Yes	-
RPA2	6118	96	1.250	1.151	76	Yes	-
RB1	5925	31	-0.102	0.802	351	-	-
ACO2	50	65	1.000	1.076	191	Yes	-
CDC16	8881	53	0.950	1.020	80	Yes	-
PPP2R1A	5518	19	0.644	0.985	249	Yes	-
ANAPC10	10393	3	0.195	0.971	46	Yes	-
PSMB2	5690	116	0.877	0.956	169	Yes	-
PSMD11	5717	124	1.095	1.106	218	Yes	-
ACTB	60	134	1.153	1.151	610	Yes	-

Interactions (55)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PPP2R1A	5518	PSMB3	5691	pp	--	int.I2D: IntAct_Mouse
ACO2	50	OGDH	4967	pp	--	int.I2D: YeastLow
RB1	5925	PPCS	79717	pd	>	reg.pazar.txt: no annot
RB1	5925	RPA2	6118	pd	>	reg.pazar.txt: no annot
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
ACO2	50	UBA1	7317	pp	--	int.I2D: YeastLow
PSMB2	5690	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
PGD	5226	RB1	5925	pd	<	reg.pazar.txt: no annot
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
RBX1	9978	PPIE	10450	pd	<>	reg.ITFP.txt: no annot
PPP2R1A	5518	ANAPC10	10393	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
RPSA	3921	VARS	7407	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	ANAPC10	10393	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
OGDH	4967	RB1	5925	pd	<	reg.ITFP.txt: no annot
PPP2R1A	5518	PSMB2	5690	pp	--	int.I2D: IntAct_Mouse
ACTB	60	PPP2R1A	5518	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
PGD	5226	UBA1	7317	pp	--	int.I2D: YeastLow
PSMB7	5695	RBX1	9978	pd	<	reg.ITFP.txt: no annot
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
VARS	7407	POLE4	56655	pd	<>	reg.ITFP.txt: no annot
PSMA2	5683	PSMB3	5691	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PPP2R1A	5518	PSMB7	5695	pp	--	int.I2D: IntAct_Mouse
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
PSMA2	5683	POLE4	56655	pd	<	reg.ITFP.txt: no annot
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMB3	5691	PSMB7	5695	pp	--	int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid
PGD	5226	PPP2R1A	5518	pp	--	int.I2D: YeastLow
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMB3	5691	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
ACTB	60	CDC16	8881	pp	--	int.I2D: YeastLow
OGDH	4967	PSMD11	5717	pp	--	int.I2D: YeastLow
UBA1	7317	VARS	7407	pp	--	int.I2D: Krogan_NonCore, YeastLow
PSMB3	5691	POLE4	56655	pd	<	reg.ITFP.txt: no annot
PSMB7	5695	PPIE	10450	pd	<	reg.ITFP.txt: no annot
PPP2R1A	5518	PSMA2	5683	pp	--	int.I2D: IntAct_Mouse
RB1	5925	TFRC	7037	pd	>	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pd	<	reg.ITFP.txt: no annot
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	VARS	7407	pd	<	reg.ITFP.txt: no annot
CDC16	8881	ANAPC10	10393	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, BIND_Yeast, HPRD, Krogan_Core, MINT_Yeast, MIPS, YeastLow; int.HPRD: in vivo
PPP2R1A	5518	UBA1	7317	pp	--	int.I2D: IntAct_Yeast, YeastLow
UBA1	7317	ANAPC10	10393	pp	--	int.I2D: IntAct_Yeast
PSMB3	5691	PSMD11	5717	pp	--	int.I2D: YeastLow
RB1	5925	PPIE	10450	pd	>	reg.pazar.txt: no annot
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (336)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.85e-12	3.03e-08	6.320	7	24	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.18e-12	5.19e-08	6.213	7	24	70
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.76e-12	7.76e-08	6.133	7	24	74
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	7.63e-12	1.25e-07	6.039	7	25	79
GO:0000278	mitotic cell cycle	3.31e-11	5.40e-07	4.220	10	52	398
GO:0000082	G1/S transition of mitotic cell cycle	7.31e-10	1.19e-05	5.114	7	33	150
GO:0006521	regulation of cellular amino acid metabolic process	5.56e-09	9.08e-05	6.213	5	21	50
GO:0005839	proteasome core complex	7.48e-09	1.22e-04	7.365	4	11	18
GO:0016071	mRNA metabolic process	1.16e-08	1.89e-04	4.541	7	34	223
GO:0004298	threonine-type endopeptidase activity	1.18e-08	1.93e-04	7.213	4	11	20
GO:0000502	proteasome complex	1.19e-08	1.95e-04	5.999	5	22	58
GO:0016032	viral process	1.51e-08	2.46e-04	3.628	9	55	540
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.14e-08	3.49e-04	5.835	5	22	65
GO:0016070	RNA metabolic process	2.35e-08	3.83e-04	4.394	7	34	247
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.87e-08	6.31e-04	5.667	5	23	73
GO:0005654	nucleoplasm	4.19e-08	6.83e-04	2.898	11	83	1095
GO:0005829	cytosol	4.72e-08	7.70e-04	2.119	15	125	2562
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	5.07e-08	8.27e-04	5.590	5	23	77
GO:0034641	cellular nitrogen compound metabolic process	9.65e-08	1.58e-03	4.652	6	25	177
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.39e-07	2.26e-03	5.302	5	23	94
GO:0000209	protein polyubiquitination	3.98e-07	6.49e-03	4.999	5	21	116
GO:0010467	gene expression	1.47e-06	2.39e-02	3.149	8	58	669
GO:0042981	regulation of apoptotic process	1.47e-06	2.40e-02	4.619	5	26	151
GO:0044281	small molecule metabolic process	2.33e-05	3.81e-01	2.366	9	57	1295
GO:0070062	extracellular vesicular exosome	2.49e-05	4.06e-01	1.823	12	98	2516
GO:0006915	apoptotic process	8.25e-05	1.00e+00	2.963	6	34	571
GO:0043066	negative regulation of apoptotic process	2.33e-04	1.00e+00	3.099	5	30	433
GO:0005680	anaphase-promoting complex	3.25e-04	1.00e+00	6.213	2	4	20
GO:0070979	protein K11-linked ubiquitination	5.53e-04	1.00e+00	5.835	2	3	26
GO:0006099	tricarboxylic acid cycle	6.89e-04	1.00e+00	5.677	2	3	29
GO:0007094	mitotic spindle assembly checkpoint	7.88e-04	1.00e+00	5.581	2	5	31
GO:0005515	protein binding	8.57e-04	1.00e+00	0.954	16	172	6127
GO:0005634	nucleus	9.59e-04	1.00e+00	1.105	14	131	4828
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	1.35e-03	1.00e+00	9.535	1	1	1
GO:0090230	regulation of centromere complex assembly	1.35e-03	1.00e+00	9.535	1	1	1
GO:0070262	peptidyl-serine dephosphorylation	1.35e-03	1.00e+00	9.535	1	1	1
GO:0004632	phosphopantothenate--cysteine ligase activity	1.35e-03	1.00e+00	9.535	1	1	1
GO:0019521	D-gluconate metabolic process	1.35e-03	1.00e+00	9.535	1	1	1
GO:0031625	ubiquitin protein ligase binding	1.74e-03	1.00e+00	3.628	3	13	180
GO:0005739	mitochondrion	2.09e-03	1.00e+00	2.089	6	24	1046
GO:0006091	generation of precursor metabolites and energy	2.12e-03	1.00e+00	4.863	2	3	51
GO:0004832	valine-tRNA ligase activity	2.69e-03	1.00e+00	8.535	1	1	2
GO:0045252	oxoglutarate dehydrogenase complex	2.69e-03	1.00e+00	8.535	1	2	2
GO:0051538	3 iron, 4 sulfur cluster binding	2.69e-03	1.00e+00	8.535	1	1	2
GO:0003994	aconitate hydratase activity	2.69e-03	1.00e+00	8.535	1	1	2
GO:0097286	iron ion import	2.69e-03	1.00e+00	8.535	1	1	2
GO:0006407	rRNA export from nucleus	2.69e-03	1.00e+00	8.535	1	1	2
GO:0006438	valyl-tRNA aminoacylation	2.69e-03	1.00e+00	8.535	1	1	2
GO:0061034	olfactory bulb mitral cell layer development	2.69e-03	1.00e+00	8.535	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.69e-03	1.00e+00	8.535	1	1	2
GO:0004998	transferrin receptor activity	2.69e-03	1.00e+00	8.535	1	1	2
GO:0019322	pentose biosynthetic process	2.69e-03	1.00e+00	8.535	1	1	2
GO:0031134	sister chromatid biorientation	2.69e-03	1.00e+00	8.535	1	1	2
GO:0005055	laminin receptor activity	2.69e-03	1.00e+00	8.535	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	2.69e-03	1.00e+00	8.535	1	2	2
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	4.04e-03	1.00e+00	7.950	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	4.04e-03	1.00e+00	7.950	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	4.04e-03	1.00e+00	7.950	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	4.04e-03	1.00e+00	7.950	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	4.04e-03	1.00e+00	7.950	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	4.04e-03	1.00e+00	7.950	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.38e-03	1.00e+00	7.535	1	1	4
GO:0030686	90S preribosome	5.38e-03	1.00e+00	7.535	1	1	4
GO:0071922	regulation of cohesin localization to chromatin	5.38e-03	1.00e+00	7.535	1	1	4
GO:0019788	NEDD8 ligase activity	5.38e-03	1.00e+00	7.535	1	1	4
GO:0006104	succinyl-CoA metabolic process	5.38e-03	1.00e+00	7.535	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	5.38e-03	1.00e+00	7.535	1	1	4
GO:0043550	regulation of lipid kinase activity	5.38e-03	1.00e+00	7.535	1	1	4
GO:0004839	ubiquitin activating enzyme activity	5.38e-03	1.00e+00	7.535	1	1	4
GO:0035189	Rb-E2F complex	5.38e-03	1.00e+00	7.535	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	5.38e-03	1.00e+00	7.535	1	1	4
GO:0034349	glial cell apoptotic process	5.38e-03	1.00e+00	7.535	1	1	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	6.72e-03	1.00e+00	7.213	1	2	5
GO:0019932	second-messenger-mediated signaling	6.72e-03	1.00e+00	7.213	1	1	5
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	6.72e-03	1.00e+00	7.213	1	1	5
GO:2000001	regulation of DNA damage checkpoint	6.72e-03	1.00e+00	7.213	1	1	5
GO:0008622	epsilon DNA polymerase complex	6.72e-03	1.00e+00	7.213	1	1	5
GO:0019941	modification-dependent protein catabolic process	6.72e-03	1.00e+00	7.213	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	6.72e-03	1.00e+00	7.213	1	1	5
GO:0043248	proteasome assembly	6.72e-03	1.00e+00	7.213	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	6.72e-03	1.00e+00	7.213	1	1	5
GO:0006102	isocitrate metabolic process	6.72e-03	1.00e+00	7.213	1	1	5
GO:0030891	VCB complex	6.72e-03	1.00e+00	7.213	1	2	5
GO:0000730	DNA recombinase assembly	6.72e-03	1.00e+00	7.213	1	3	5
GO:0006734	NADH metabolic process	6.72e-03	1.00e+00	7.213	1	1	5
GO:0030976	thiamine pyrophosphate binding	6.72e-03	1.00e+00	7.213	1	1	5
GO:0016605	PML body	6.75e-03	1.00e+00	4.011	2	5	92
GO:0043353	enucleate erythrocyte differentiation	8.06e-03	1.00e+00	6.950	1	1	6
GO:0009108	coenzyme biosynthetic process	8.06e-03	1.00e+00	6.950	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	8.06e-03	1.00e+00	6.950	1	1	6
GO:0006101	citrate metabolic process	8.06e-03	1.00e+00	6.950	1	1	6
GO:0021860	pyramidal neuron development	8.06e-03	1.00e+00	6.950	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	8.06e-03	1.00e+00	6.950	1	1	6
GO:0021695	cerebellar cortex development	8.06e-03	1.00e+00	6.950	1	1	6
GO:0030957	Tat protein binding	8.06e-03	1.00e+00	6.950	1	4	6
GO:0000028	ribosomal small subunit assembly	9.40e-03	1.00e+00	6.728	1	1	7
GO:0002161	aminoacyl-tRNA editing activity	9.40e-03	1.00e+00	6.728	1	2	7
GO:0031462	Cul2-RING ubiquitin ligase complex	9.40e-03	1.00e+00	6.728	1	2	7
GO:0030867	rough endoplasmic reticulum membrane	9.40e-03	1.00e+00	6.728	1	1	7
GO:0016018	cyclosporin A binding	9.40e-03	1.00e+00	6.728	1	1	7
GO:0015630	microtubule cytoskeleton	9.86e-03	1.00e+00	3.728	2	5	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.02e-02	1.00e+00	3.702	2	10	114
GO:0005819	spindle	1.02e-02	1.00e+00	3.702	2	7	114
GO:0072562	blood microparticle	1.05e-02	1.00e+00	3.677	2	4	116
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.07e-02	1.00e+00	6.535	1	2	8
GO:0070688	MLL5-L complex	1.07e-02	1.00e+00	6.535	1	1	8
GO:0006554	lysine catabolic process	1.07e-02	1.00e+00	6.535	1	2	8
GO:0045116	protein neddylation	1.07e-02	1.00e+00	6.535	1	2	8
GO:0019773	proteasome core complex, alpha-subunit complex	1.07e-02	1.00e+00	6.535	1	5	8
GO:0044237	cellular metabolic process	1.09e-02	1.00e+00	3.652	2	3	118
GO:0015937	coenzyme A biosynthetic process	1.21e-02	1.00e+00	6.365	1	1	9
GO:0097284	hepatocyte apoptotic process	1.21e-02	1.00e+00	6.365	1	2	9
GO:0000075	cell cycle checkpoint	1.21e-02	1.00e+00	6.365	1	2	9
GO:0006450	regulation of translational fidelity	1.34e-02	1.00e+00	6.213	1	2	10
GO:0007084	mitotic nuclear envelope reassembly	1.34e-02	1.00e+00	6.213	1	1	10
GO:0015939	pantothenate metabolic process	1.34e-02	1.00e+00	6.213	1	1	10
GO:0021756	striatum development	1.34e-02	1.00e+00	6.213	1	1	10
GO:0006098	pentose-phosphate shunt	1.47e-02	1.00e+00	6.076	1	3	11
GO:0010569	regulation of double-strand break repair via homologous recombination	1.47e-02	1.00e+00	6.076	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.47e-02	1.00e+00	6.076	1	3	11
GO:0042551	neuron maturation	1.47e-02	1.00e+00	6.076	1	2	11
GO:0045651	positive regulation of macrophage differentiation	1.47e-02	1.00e+00	6.076	1	2	11
GO:0051146	striated muscle cell differentiation	1.61e-02	1.00e+00	5.950	1	1	12
GO:0006275	regulation of DNA replication	1.61e-02	1.00e+00	5.950	1	2	12
GO:0021794	thalamus development	1.61e-02	1.00e+00	5.950	1	1	12
GO:0030111	regulation of Wnt signaling pathway	1.61e-02	1.00e+00	5.950	1	1	12
GO:0005838	proteasome regulatory particle	1.61e-02	1.00e+00	5.950	1	7	12
GO:0006457	protein folding	1.70e-02	1.00e+00	3.316	2	8	149
GO:0005662	DNA replication factor A complex	1.74e-02	1.00e+00	5.835	1	3	13
GO:0045780	positive regulation of bone resorption	1.74e-02	1.00e+00	5.835	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.87e-02	1.00e+00	5.728	1	4	14
GO:0006672	ceramide metabolic process	2.00e-02	1.00e+00	5.628	1	1	15
GO:0045445	myoblast differentiation	2.00e-02	1.00e+00	5.628	1	2	15
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	2.00e-02	1.00e+00	5.628	1	2	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	2.00e-02	1.00e+00	5.628	1	1	15
GO:0016514	SWI/SNF complex	2.00e-02	1.00e+00	5.628	1	3	15
GO:0050998	nitric-oxide synthase binding	2.14e-02	1.00e+00	5.535	1	1	16
GO:0006103	2-oxoglutarate metabolic process	2.14e-02	1.00e+00	5.535	1	1	16
GO:0010243	response to organonitrogen compound	2.27e-02	1.00e+00	5.448	1	2	17
GO:0045070	positive regulation of viral genome replication	2.27e-02	1.00e+00	5.448	1	1	17
GO:0022624	proteasome accessory complex	2.27e-02	1.00e+00	5.448	1	9	17
GO:0035861	site of double-strand break	2.40e-02	1.00e+00	5.365	1	1	18
GO:0016020	membrane	2.46e-02	1.00e+00	1.350	6	80	1746
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.53e-02	1.00e+00	5.287	1	1	19
GO:0048863	stem cell differentiation	2.53e-02	1.00e+00	5.287	1	1	19
GO:0007088	regulation of mitosis	2.53e-02	1.00e+00	5.287	1	1	19
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.66e-02	1.00e+00	5.213	1	2	20
GO:0008601	protein phosphatase type 2A regulator activity	2.66e-02	1.00e+00	5.213	1	3	20
GO:0006298	mismatch repair	2.66e-02	1.00e+00	5.213	1	6	20
GO:0000159	protein phosphatase type 2A complex	2.66e-02	1.00e+00	5.213	1	2	20
GO:0045595	regulation of cell differentiation	2.79e-02	1.00e+00	5.143	1	1	21
GO:0000718	nucleotide-excision repair, DNA damage removal	2.79e-02	1.00e+00	5.143	1	5	21
GO:0030316	osteoclast differentiation	2.93e-02	1.00e+00	5.076	1	2	22
GO:0000792	heterochromatin	2.93e-02	1.00e+00	5.076	1	2	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.93e-02	1.00e+00	5.076	1	5	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	2.93e-02	1.00e+00	5.076	1	3	22
GO:0032201	telomere maintenance via semi-conservative replication	2.93e-02	1.00e+00	5.076	1	7	22
GO:0030863	cortical cytoskeleton	2.93e-02	1.00e+00	5.076	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.93e-02	1.00e+00	5.076	1	4	22
GO:0030057	desmosome	3.06e-02	1.00e+00	5.011	1	1	23
GO:0031463	Cul3-RING ubiquitin ligase complex	3.06e-02	1.00e+00	5.011	1	2	23
GO:0043236	laminin binding	3.06e-02	1.00e+00	5.011	1	1	23
GO:0006513	protein monoubiquitination	3.06e-02	1.00e+00	5.011	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	3.06e-02	1.00e+00	5.011	1	4	23
GO:0045879	negative regulation of smoothened signaling pathway	3.06e-02	1.00e+00	5.011	1	1	23
GO:0000722	telomere maintenance via recombination	3.45e-02	1.00e+00	4.835	1	7	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.45e-02	1.00e+00	4.835	1	2	26
GO:0000188	inactivation of MAPK activity	3.58e-02	1.00e+00	4.780	1	1	27
GO:0048565	digestive tract development	3.58e-02	1.00e+00	4.780	1	1	27
GO:0003823	antigen binding	3.71e-02	1.00e+00	4.728	1	1	28
GO:0010033	response to organic substance	3.71e-02	1.00e+00	4.728	1	2	28
GO:0043022	ribosome binding	3.71e-02	1.00e+00	4.728	1	3	28
GO:0031492	nucleosomal DNA binding	3.71e-02	1.00e+00	4.728	1	4	28
GO:0019894	kinesin binding	3.71e-02	1.00e+00	4.728	1	1	28
GO:0007067	mitotic nuclear division	3.83e-02	1.00e+00	2.683	2	13	231
GO:0019005	SCF ubiquitin ligase complex	3.84e-02	1.00e+00	4.677	1	1	29
GO:0003887	DNA-directed DNA polymerase activity	3.84e-02	1.00e+00	4.677	1	3	29
GO:0071897	DNA biosynthetic process	3.84e-02	1.00e+00	4.677	1	2	29
GO:0005759	mitochondrial matrix	3.89e-02	1.00e+00	2.671	2	12	233
GO:0007346	regulation of mitotic cell cycle	3.97e-02	1.00e+00	4.628	1	3	30
GO:0006271	DNA strand elongation involved in DNA replication	4.10e-02	1.00e+00	4.581	1	9	31
GO:0007093	mitotic cell cycle checkpoint	4.10e-02	1.00e+00	4.581	1	2	31
GO:0050661	NADP binding	4.23e-02	1.00e+00	4.535	1	1	32
GO:0051219	phosphoprotein binding	4.23e-02	1.00e+00	4.535	1	3	32
GO:0033572	transferrin transport	4.23e-02	1.00e+00	4.535	1	6	32
GO:0031072	heat shock protein binding	4.36e-02	1.00e+00	4.491	1	2	33
GO:0000413	protein peptidyl-prolyl isomerization	4.49e-02	1.00e+00	4.448	1	1	34
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4.49e-02	1.00e+00	4.448	1	1	34
GO:0005876	spindle microtubule	4.49e-02	1.00e+00	4.448	1	3	34
GO:0004842	ubiquitin-protein transferase activity	4.61e-02	1.00e+00	2.535	2	4	256
GO:0034332	adherens junction organization	4.74e-02	1.00e+00	4.365	1	1	36
GO:0051402	neuron apoptotic process	4.74e-02	1.00e+00	4.365	1	2	36
GO:0001895	retina homeostasis	4.74e-02	1.00e+00	4.365	1	1	36
GO:0001102	RNA polymerase II activating transcription factor binding	4.87e-02	1.00e+00	4.326	1	4	37
GO:0051084	'de novo' posttranslational protein folding	4.87e-02	1.00e+00	4.326	1	4	37
GO:0006281	DNA repair	4.87e-02	1.00e+00	2.491	2	22	264
GO:0051539	4 iron, 4 sulfur cluster binding	4.87e-02	1.00e+00	4.326	1	3	37
GO:0070527	platelet aggregation	5.00e-02	1.00e+00	4.287	1	2	38
GO:0050681	androgen receptor binding	5.00e-02	1.00e+00	4.287	1	4	38
GO:0021766	hippocampus development	5.13e-02	1.00e+00	4.250	1	4	39
GO:0006284	base-excision repair	5.13e-02	1.00e+00	4.250	1	7	39
GO:0006096	glycolytic process	5.13e-02	1.00e+00	4.250	1	4	39
GO:0022627	cytosolic small ribosomal subunit	5.13e-02	1.00e+00	4.250	1	3	39
GO:0000781	chromosome, telomeric region	5.26e-02	1.00e+00	4.213	1	2	40
GO:0044822	poly(A) RNA binding	5.34e-02	1.00e+00	1.461	4	50	1078
GO:0030521	androgen receptor signaling pathway	5.39e-02	1.00e+00	4.177	1	2	41
GO:0006418	tRNA aminoacylation for protein translation	5.51e-02	1.00e+00	4.143	1	5	42
GO:0004722	protein serine/threonine phosphatase activity	5.51e-02	1.00e+00	4.143	1	1	42
GO:0035914	skeletal muscle cell differentiation	5.51e-02	1.00e+00	4.143	1	1	42
GO:0030155	regulation of cell adhesion	5.51e-02	1.00e+00	4.143	1	3	42
GO:0014070	response to organic cyclic compound	5.64e-02	1.00e+00	4.109	1	3	43
GO:0043966	histone H3 acetylation	5.90e-02	1.00e+00	4.043	1	2	45
GO:0021762	substantia nigra development	6.02e-02	1.00e+00	4.011	1	1	46
GO:0001047	core promoter binding	6.02e-02	1.00e+00	4.011	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	6.02e-02	1.00e+00	4.011	1	8	46
GO:0016567	protein ubiquitination	6.07e-02	1.00e+00	2.311	2	5	299
GO:0005905	coated pit	6.66e-02	1.00e+00	3.863	1	2	51
GO:0040008	regulation of growth	6.66e-02	1.00e+00	3.863	1	3	51
GO:0003684	damaged DNA binding	6.66e-02	1.00e+00	3.863	1	11	51
GO:0000775	chromosome, centromeric region	6.78e-02	1.00e+00	3.835	1	2	52
GO:0003725	double-stranded RNA binding	7.04e-02	1.00e+00	3.780	1	6	54
GO:0019900	kinase binding	7.04e-02	1.00e+00	3.780	1	1	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	7.04e-02	1.00e+00	3.780	1	5	54
GO:0050680	negative regulation of epithelial cell proliferation	7.04e-02	1.00e+00	3.780	1	1	54
GO:0000932	cytoplasmic mRNA processing body	7.29e-02	1.00e+00	3.728	1	3	56
GO:0006879	cellular iron ion homeostasis	7.41e-02	1.00e+00	3.702	1	5	57
GO:0000724	double-strand break repair via homologous recombination	7.41e-02	1.00e+00	3.702	1	6	57
GO:0051087	chaperone binding	7.66e-02	1.00e+00	3.652	1	6	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	7.66e-02	1.00e+00	3.652	1	4	59
GO:0045216	cell-cell junction organization	7.66e-02	1.00e+00	3.652	1	2	59
GO:0000723	telomere maintenance	7.66e-02	1.00e+00	3.652	1	8	59
GO:0031966	mitochondrial membrane	7.66e-02	1.00e+00	3.652	1	1	59
GO:0006302	double-strand break repair	8.04e-02	1.00e+00	3.581	1	8	62
GO:0019903	protein phosphatase binding	8.16e-02	1.00e+00	3.558	1	4	63
GO:0007059	chromosome segregation	8.29e-02	1.00e+00	3.535	1	3	64
GO:0006469	negative regulation of protein kinase activity	8.41e-02	1.00e+00	3.513	1	2	65
GO:0001558	regulation of cell growth	8.53e-02	1.00e+00	3.491	1	4	66
GO:0006338	chromatin remodeling	8.78e-02	1.00e+00	3.448	1	4	68
GO:0006289	nucleotide-excision repair	8.90e-02	1.00e+00	3.426	1	12	69
GO:0003697	single-stranded DNA binding	8.90e-02	1.00e+00	3.426	1	9	69
GO:0034329	cell junction assembly	9.15e-02	1.00e+00	3.385	1	1	71
GO:0055037	recycling endosome	9.40e-02	1.00e+00	3.345	1	2	73
GO:0000785	chromatin	9.40e-02	1.00e+00	3.345	1	5	73
GO:0006767	water-soluble vitamin metabolic process	9.64e-02	1.00e+00	3.306	1	3	75
GO:0007265	Ras protein signal transduction	9.64e-02	1.00e+00	3.306	1	3	75
GO:0031175	neuron projection development	9.64e-02	1.00e+00	3.306	1	1	75
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	9.76e-02	1.00e+00	3.287	1	3	76
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	9.89e-02	1.00e+00	3.268	1	5	77
GO:0046982	protein heterodimerization activity	9.99e-02	1.00e+00	1.895	2	11	399
GO:0006766	vitamin metabolic process	1.00e-01	1.00e+00	3.250	1	3	78
GO:0071013	catalytic step 2 spliceosome	1.01e-01	1.00e+00	3.231	1	7	79
GO:0019083	viral transcription	1.04e-01	1.00e+00	3.195	1	8	81
GO:0047485	protein N-terminus binding	1.10e-01	1.00e+00	3.109	1	4	86
GO:0006898	receptor-mediated endocytosis	1.10e-01	1.00e+00	3.109	1	2	86
GO:0006415	translational termination	1.11e-01	1.00e+00	3.092	1	8	87
GO:0042470	melanosome	1.17e-01	1.00e+00	3.011	1	10	92
GO:0006928	cellular component movement	1.17e-01	1.00e+00	3.011	1	7	92
GO:0006414	translational elongation	1.18e-01	1.00e+00	2.996	1	11	93
GO:0005200	structural constituent of cytoskeleton	1.18e-01	1.00e+00	2.996	1	7	93
GO:0071456	cellular response to hypoxia	1.24e-01	1.00e+00	2.920	1	4	98
GO:0006470	protein dephosphorylation	1.25e-01	1.00e+00	2.906	1	1	99
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.31e-01	1.00e+00	2.835	1	8	104
GO:0014069	postsynaptic density	1.34e-01	1.00e+00	2.807	1	1	106
GO:0016023	cytoplasmic membrane-bounded vesicle	1.35e-01	1.00e+00	2.794	1	3	107
GO:0042127	regulation of cell proliferation	1.39e-01	1.00e+00	2.741	1	4	111
GO:0006461	protein complex assembly	1.39e-01	1.00e+00	2.741	1	6	111
GO:0042802	identical protein binding	1.41e-01	1.00e+00	1.595	2	18	491
GO:0030308	negative regulation of cell growth	1.42e-01	1.00e+00	2.715	1	6	113
GO:0030529	ribonucleoprotein complex	1.43e-01	1.00e+00	2.702	1	8	114
GO:0044267	cellular protein metabolic process	1.43e-01	1.00e+00	1.584	2	24	495
GO:0019058	viral life cycle	1.44e-01	1.00e+00	2.690	1	10	115
GO:0006325	chromatin organization	1.53e-01	1.00e+00	2.592	1	4	123
GO:0007219	Notch signaling pathway	1.56e-01	1.00e+00	2.569	1	4	125
GO:0006260	DNA replication	1.56e-01	1.00e+00	2.569	1	12	125
GO:0007050	cell cycle arrest	1.57e-01	1.00e+00	2.558	1	7	126
GO:0005506	iron ion binding	1.58e-01	1.00e+00	2.546	1	3	127
GO:0006511	ubiquitin-dependent protein catabolic process	1.58e-01	1.00e+00	2.546	1	5	127
GO:0006413	translational initiation	1.63e-01	1.00e+00	2.502	1	12	131
GO:0009615	response to virus	1.64e-01	1.00e+00	2.491	1	6	132
GO:0000790	nuclear chromatin	1.65e-01	1.00e+00	2.480	1	7	133
GO:0031982	vesicle	1.66e-01	1.00e+00	2.469	1	10	134
GO:0000086	G2/M transition of mitotic cell cycle	1.69e-01	1.00e+00	2.437	1	7	137
GO:0003735	structural constituent of ribosome	1.74e-01	1.00e+00	2.395	1	8	141
GO:0061024	membrane organization	1.79e-01	1.00e+00	2.345	1	5	146
GO:0010008	endosome membrane	1.92e-01	1.00e+00	2.240	1	6	157
GO:0006974	cellular response to DNA damage stimulus	1.93e-01	1.00e+00	2.231	1	8	158
GO:0008543	fibroblast growth factor receptor signaling pathway	1.94e-01	1.00e+00	2.222	1	4	159
GO:0000398	mRNA splicing, via spliceosome	2.00e-01	1.00e+00	2.169	1	12	165
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2.04e-01	1.00e+00	2.143	1	5	168
GO:0030424	axon	2.08e-01	1.00e+00	2.109	1	3	172
GO:0005768	endosome	2.10e-01	1.00e+00	2.092	1	5	174
GO:0009897	external side of plasma membrane	2.20e-01	1.00e+00	2.019	1	4	183
GO:0015629	actin cytoskeleton	2.20e-01	1.00e+00	2.019	1	5	183
GO:0032403	protein complex binding	2.22e-01	1.00e+00	2.004	1	7	185
GO:0005765	lysosomal membrane	2.56e-01	1.00e+00	1.767	1	5	218
GO:0008380	RNA splicing	2.70e-01	1.00e+00	1.677	1	13	232
GO:0006412	translation	2.73e-01	1.00e+00	1.658	1	15	235
GO:0005524	ATP binding	2.74e-01	1.00e+00	0.717	3	46	1354
GO:0003713	transcription coactivator activity	2.77e-01	1.00e+00	1.634	1	10	239
GO:0008134	transcription factor binding	2.84e-01	1.00e+00	1.592	1	8	246
GO:0000166	nucleotide binding	3.09e-01	1.00e+00	1.448	1	6	272
GO:0005975	carbohydrate metabolic process	3.11e-01	1.00e+00	1.437	1	5	274
GO:0019899	enzyme binding	3.24e-01	1.00e+00	1.365	1	11	288
GO:0043234	protein complex	3.35e-01	1.00e+00	1.306	1	17	300
GO:0005856	cytoskeleton	3.45e-01	1.00e+00	1.254	1	8	311
GO:0019901	protein kinase binding	3.53e-01	1.00e+00	1.213	1	21	320
GO:0007411	axon guidance	3.60e-01	1.00e+00	1.182	1	9	327
GO:0008283	cell proliferation	3.63e-01	1.00e+00	1.164	1	12	331
GO:0043231	intracellular membrane-bounded organelle	3.64e-01	1.00e+00	1.160	1	8	332
GO:0005813	centrosome	3.70e-01	1.00e+00	1.130	1	12	339
GO:0003723	RNA binding	3.84e-01	1.00e+00	1.063	1	19	355
GO:0043565	sequence-specific DNA binding	3.92e-01	1.00e+00	1.023	1	4	365
GO:0005925	focal adhesion	3.96e-01	1.00e+00	1.004	1	18	370
GO:0005615	extracellular space	3.99e-01	1.00e+00	0.555	2	17	1010
GO:0005730	nucleolus	4.00e-01	1.00e+00	0.402	3	70	1684
GO:0007155	cell adhesion	4.08e-01	1.00e+00	0.950	1	8	384
GO:0009986	cell surface	4.38e-01	1.00e+00	0.814	1	9	422
GO:0045892	negative regulation of transcription, DNA-templated	4.40e-01	1.00e+00	0.807	1	14	424
GO:0006355	regulation of transcription, DNA-templated	4.44e-01	1.00e+00	0.426	2	17	1104
GO:0007596	blood coagulation	4.70e-01	1.00e+00	0.677	1	14	464
GO:0055114	oxidation-reduction process	4.82e-01	1.00e+00	0.625	1	11	481
GO:0045893	positive regulation of transcription, DNA-templated	4.87e-01	1.00e+00	0.607	1	17	487
GO:0055085	transmembrane transport	5.06e-01	1.00e+00	0.529	1	8	514
GO:0048471	perinuclear region of cytoplasm	5.12e-01	1.00e+00	0.504	1	12	523
GO:0045087	innate immune response	5.71e-01	1.00e+00	0.268	1	20	616
GO:0005794	Golgi apparatus	5.91e-01	1.00e+00	0.191	1	14	650
GO:0003700	sequence-specific DNA binding transcription factor activity	6.44e-01	1.00e+00	-0.012	1	11	748
GO:0005737	cytoplasm	6.51e-01	1.00e+00	-0.100	5	98	3976
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.74e-01	1.00e+00	-0.129	1	19	811
GO:0005887	integral component of plasma membrane	7.37e-01	1.00e+00	-0.373	1	7	961
GO:0005576	extracellular region	7.68e-01	1.00e+00	-0.500	1	9	1049
GO:0008270	zinc ion binding	7.74e-01	1.00e+00	-0.524	1	12	1067
GO:0003677	DNA binding	8.51e-01	1.00e+00	-0.865	1	26	1351
GO:0046872	metal ion binding	8.74e-01	1.00e+00	-0.982	1	24	1465
GO:0006351	transcription, DNA-templated	8.94e-01	1.00e+00	-1.095	1	25	1585
GO:0005886	plasma membrane	9.15e-01	1.00e+00	-0.934	2	38	2834

Wolf-ratios-Mammosphere-Adherent

meta-int-snw-10393

Interacting subnets

Genes (22)

Interactions (55)

Related GO terms (336)