int-snw-9133

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.990	1.04e-17	7.06e-04	1.58e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-9133 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPS11	6205	36	0.993	1.113	175	Yes	-
PSMD3	5709	57	0.986	1.106	146	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
PSMB2	5690	18	0.877	1.026	117	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
[ CCNB2 ]	9133	1	-0.027	0.990	82	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (16)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMD11	5717	CCNB2	9133	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	CCNB2	9133	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
PSMD3	5709	CCNB2	9133	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	CCNB2	9133	pp	--	int.I2D: BIND_Yeast, MINT_Yeast, MIPS, IntAct_Yeast, YeastLow

Related GO terms (127)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016071	mRNA metabolic process	1.03e-09	1.49e-05	5.430	6	31	223
GO:0016070	RNA metabolic process	1.91e-09	2.76e-05	5.283	6	32	247
GO:0005829	cytosol	1.38e-07	1.98e-03	2.531	9	132	2496
GO:0016032	viral process	1.91e-07	2.76e-03	4.170	6	55	534
GO:0016020	membrane	2.71e-07	3.91e-03	2.931	8	90	1681
GO:0010467	gene expression	7.26e-07	1.05e-02	3.845	6	59	669
GO:0006521	regulation of cellular amino acid metabolic process	3.25e-06	4.68e-02	6.587	3	17	50
GO:0070062	extracellular vesicular exosome	4.47e-06	6.44e-02	2.417	8	104	2400
GO:0000502	proteasome complex	5.10e-06	7.35e-02	6.373	3	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.87e-06	9.91e-02	6.231	3	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.20e-06	1.04e-01	6.209	3	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.01e-06	1.30e-01	6.102	3	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	9.81e-06	1.41e-01	6.061	3	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.07e-05	1.54e-01	6.022	3	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.11e-05	1.60e-01	6.002	3	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.30e-05	1.87e-01	5.927	3	23	79
GO:0019083	viral transcription	1.40e-05	2.02e-01	5.891	3	10	81
GO:0006415	translational termination	1.73e-05	2.50e-01	5.788	3	10	87
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.05e-05	2.96e-01	5.708	3	21	92
GO:0006414	translational elongation	2.12e-05	3.06e-01	5.692	3	13	93
GO:0005838	proteasome regulatory particle	2.28e-05	3.28e-01	8.061	2	7	12
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.96e-05	4.28e-01	5.531	3	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.90e-05	5.63e-01	5.398	3	11	114
GO:0019058	viral life cycle	4.01e-05	5.78e-01	5.386	3	13	115
GO:0000209	protein polyubiquitination	4.11e-05	5.93e-01	5.373	3	20	116
GO:0022624	proteasome accessory complex	4.68e-05	6.76e-01	7.559	2	8	17
GO:0006413	translational initiation	5.91e-05	8.52e-01	5.198	3	17	131
GO:0000278	mitotic cell cycle	6.02e-05	8.68e-01	4.035	4	48	391
GO:0003735	structural constituent of ribosome	6.75e-05	9.74e-01	5.133	3	10	137
GO:0000082	G1/S transition of mitotic cell cycle	8.67e-05	1.00e+00	5.012	3	32	149
GO:0042981	regulation of apoptotic process	8.85e-05	1.00e+00	5.002	3	24	150
GO:0044267	cellular protein metabolic process	1.27e-04	1.00e+00	3.757	4	29	474
GO:0034641	cellular nitrogen compound metabolic process	1.31e-04	1.00e+00	4.813	3	20	171
GO:0005654	nucleoplasm	2.30e-04	1.00e+00	2.889	5	76	1082
GO:0022627	cytosolic small ribosomal subunit	2.53e-04	1.00e+00	6.361	2	4	39
GO:0006412	translation	3.13e-04	1.00e+00	4.386	3	20	230
GO:0019521	D-gluconate metabolic process	6.24e-04	1.00e+00	10.646	1	1	1
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.25e-03	1.00e+00	9.646	1	1	2
GO:0019322	pentose biosynthetic process	1.25e-03	1.00e+00	9.646	1	2	2
GO:0005055	laminin receptor activity	1.25e-03	1.00e+00	9.646	1	1	2
GO:0006407	rRNA export from nucleus	1.25e-03	1.00e+00	9.646	1	1	2
GO:0043066	negative regulation of apoptotic process	1.86e-03	1.00e+00	3.503	3	31	424
GO:0009051	pentose-phosphate shunt, oxidative branch	1.87e-03	1.00e+00	9.061	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.87e-03	1.00e+00	9.061	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.49e-03	1.00e+00	8.646	1	1	4
GO:0030686	90S preribosome	2.49e-03	1.00e+00	8.646	1	1	4
GO:0043248	proteasome assembly	3.12e-03	1.00e+00	8.324	1	1	5
GO:0030957	Tat protein binding	3.74e-03	1.00e+00	8.061	1	3	6
GO:0006915	apoptotic process	4.00e-03	1.00e+00	3.115	3	33	555
GO:0000028	ribosomal small subunit assembly	4.36e-03	1.00e+00	7.839	1	1	7
GO:0044281	small molecule metabolic process	4.42e-03	1.00e+00	2.404	4	58	1211
GO:0070688	MLL5-L complex	4.98e-03	1.00e+00	7.646	1	1	8
GO:0006098	pentose-phosphate shunt	6.22e-03	1.00e+00	7.324	1	4	10
GO:0042273	ribosomal large subunit biogenesis	8.09e-03	1.00e+00	6.946	1	4	13
GO:0030234	enzyme regulator activity	8.09e-03	1.00e+00	6.946	1	3	13
GO:0035267	NuA4 histone acetyltransferase complex	8.70e-03	1.00e+00	6.839	1	4	14
GO:0050998	nitric-oxide synthase binding	9.94e-03	1.00e+00	6.646	1	1	16
GO:0042176	regulation of protein catabolic process	9.94e-03	1.00e+00	6.646	1	3	16
GO:0010243	response to organonitrogen compound	1.06e-02	1.00e+00	6.559	1	3	17
GO:0005839	proteasome core complex	1.12e-02	1.00e+00	6.476	1	8	18
GO:0004298	threonine-type endopeptidase activity	1.18e-02	1.00e+00	6.398	1	8	19
GO:0048863	stem cell differentiation	1.18e-02	1.00e+00	6.398	1	1	19
GO:0043029	T cell homeostasis	1.30e-02	1.00e+00	6.254	1	1	21
GO:0030863	cortical cytoskeleton	1.36e-02	1.00e+00	6.187	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.36e-02	1.00e+00	6.187	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.43e-02	1.00e+00	6.123	1	4	23
GO:0043236	laminin binding	1.43e-02	1.00e+00	6.123	1	1	23
GO:0040007	growth	1.55e-02	1.00e+00	6.002	1	2	25
GO:0019901	protein kinase binding	1.57e-02	1.00e+00	3.338	2	21	317
GO:0031492	nucleosomal DNA binding	1.67e-02	1.00e+00	5.891	1	4	27
GO:0019843	rRNA binding	1.67e-02	1.00e+00	5.891	1	3	27
GO:0043022	ribosome binding	1.67e-02	1.00e+00	5.891	1	3	27
GO:0050661	NADP binding	1.67e-02	1.00e+00	5.891	1	2	27
GO:0019894	kinesin binding	1.73e-02	1.00e+00	5.839	1	1	28
GO:0005925	focal adhesion	2.05e-02	1.00e+00	3.130	2	19	366
GO:0001895	retina homeostasis	2.10e-02	1.00e+00	5.559	1	1	34
GO:0034332	adherens junction organization	2.22e-02	1.00e+00	5.476	1	1	36
GO:0007077	mitotic nuclear envelope disassembly	2.22e-02	1.00e+00	5.476	1	1	36
GO:0048538	thymus development	2.22e-02	1.00e+00	5.476	1	2	36
GO:0051084	'de novo' posttranslational protein folding	2.29e-02	1.00e+00	5.437	1	4	37
GO:0070527	platelet aggregation	2.35e-02	1.00e+00	5.398	1	2	38
GO:0044822	poly(A) RNA binding	2.35e-02	1.00e+00	2.187	3	49	1056
GO:0014070	response to organic cyclic compound	2.65e-02	1.00e+00	5.220	1	4	43
GO:0021762	substantia nigra development	2.71e-02	1.00e+00	5.187	1	2	44
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	2.77e-02	1.00e+00	5.154	1	2	45
GO:0022625	cytosolic large ribosomal subunit	3.02e-02	1.00e+00	5.031	1	6	49
GO:0005515	protein binding	3.23e-02	1.00e+00	0.897	7	184	6024
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.26e-02	1.00e+00	4.918	1	5	53
GO:0045216	cell-cell junction organization	3.32e-02	1.00e+00	4.891	1	2	54
GO:0005840	ribosome	3.56e-02	1.00e+00	4.788	1	1	58
GO:0034329	cell junction assembly	4.17e-02	1.00e+00	4.559	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.53e-02	1.00e+00	4.437	1	6	74
GO:0005200	structural constituent of cytoskeleton	5.54e-02	1.00e+00	4.138	1	8	91
GO:0006928	cellular component movement	5.54e-02	1.00e+00	4.138	1	7	91
GO:0001649	osteoblast differentiation	5.60e-02	1.00e+00	4.123	1	6	92
GO:0006364	rRNA processing	5.72e-02	1.00e+00	4.092	1	6	94
GO:0051726	regulation of cell cycle	5.89e-02	1.00e+00	4.046	1	5	97
GO:0014069	postsynaptic density	6.37e-02	1.00e+00	3.932	1	3	105
GO:0015630	microtubule cytoskeleton	6.66e-02	1.00e+00	3.865	1	4	110
GO:0072562	blood microparticle	6.72e-02	1.00e+00	3.852	1	3	111
GO:0030529	ribonucleoprotein complex	6.78e-02	1.00e+00	3.839	1	8	112
GO:0006325	chromatin organization	7.13e-02	1.00e+00	3.764	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	7.60e-02	1.00e+00	3.669	1	5	126
GO:0000790	nuclear chromatin	7.77e-02	1.00e+00	3.635	1	9	129
GO:0000086	G2/M transition of mitotic cell cycle	8.18e-02	1.00e+00	3.559	1	9	136
GO:0006457	protein folding	8.58e-02	1.00e+00	3.486	1	7	143
GO:0061024	membrane organization	8.69e-02	1.00e+00	3.466	1	7	145
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.84e-02	1.00e+00	3.280	1	7	165
GO:0030424	axon	9.90e-02	1.00e+00	3.271	1	4	166
GO:0001701	in utero embryonic development	1.19e-01	1.00e+00	2.995	1	8	201
GO:0005634	nucleus	1.20e-01	1.00e+00	0.814	5	136	4559
GO:0007067	mitotic nuclear division	1.33e-01	1.00e+00	2.820	1	14	227
GO:0005975	carbohydrate metabolic process	1.47e-01	1.00e+00	2.663	1	9	253
GO:0005856	cytoskeleton	1.68e-01	1.00e+00	2.461	1	12	291
GO:0043234	protein complex	1.70e-01	1.00e+00	2.442	1	18	295
GO:0007411	axon guidance	1.82e-01	1.00e+00	2.329	1	13	319
GO:0005813	centrosome	1.86e-01	1.00e+00	2.297	1	14	326
GO:0005737	cytoplasm	1.87e-01	1.00e+00	0.767	4	110	3767
GO:0003723	RNA binding	1.94e-01	1.00e+00	2.228	1	20	342
GO:0007155	cell adhesion	2.08e-01	1.00e+00	2.119	1	6	369
GO:0055114	oxidation-reduction process	2.34e-01	1.00e+00	1.932	1	12	420
GO:0007596	blood coagulation	2.51e-01	1.00e+00	1.816	1	18	455
GO:0005730	nucleolus	2.73e-01	1.00e+00	0.966	2	69	1641
GO:0045087	innate immune response	3.16e-01	1.00e+00	1.427	1	24	596
GO:0005615	extracellular space	4.61e-01	1.00e+00	0.744	1	17	957
GO:0005524	ATP binding	5.72e-01	1.00e+00	0.304	1	60	1298
GO:0005886	plasma membrane	8.31e-01	1.00e+00	-0.688	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-9133

Statistics

Genes (9)

Interactions (16)

Related GO terms (127)