int-snw-7328

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.923	4.40e-15	3.14e-03	4.76e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-7328 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ UBE2H ]	7328	1	0.417	0.923	96	Yes	-
ACO2	50	50	1.000	1.076	191	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-
ATP6V1B2	526	44	0.881	1.076	278	-	-
UBA1	7317	4	0.555	0.971	207	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PGD	5226	UBA1	7317	pp	--	int.I2D: YeastLow
ATP6V1B2	526	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
ATP6V1B2	526	UBA1	7317	pp	--	int.I2D: IntAct_Yeast
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
HSPD1	3329	UBA1	7317	pp	--	int.I2D: IntAct_Yeast
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
ACO2	50	UBE2H	7328	pp	--	int.I2D: BioGrid_Yeast
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
ACO2	50	HSPD1	3329	pp	--	int.I2D: IntAct_Yeast
ACO2	50	UBA1	7317	pp	--	int.I2D: YeastLow
UBA1	7317	UBE2H	7328	pp	--	int.I2D: IntAct_Yeast

Related GO terms (148)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0070062	extracellular vesicular exosome	4.35e-04	1.00e+00	2.172	6	104	2400
GO:0005829	cytosol	5.44e-04	1.00e+00	2.116	6	132	2496
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	5.55e-04	1.00e+00	10.816	1	1	1
GO:0048291	isotype switching to IgG isotypes	5.55e-04	1.00e+00	10.816	1	1	1
GO:0019521	D-gluconate metabolic process	5.55e-04	1.00e+00	10.816	1	1	1
GO:0002368	B cell cytokine production	5.55e-04	1.00e+00	10.816	1	1	1
GO:0051538	3 iron, 4 sulfur cluster binding	1.11e-03	1.00e+00	9.816	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.11e-03	1.00e+00	9.816	1	1	2
GO:0019322	pentose biosynthetic process	1.11e-03	1.00e+00	9.816	1	2	2
GO:0003994	aconitate hydratase activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0005055	laminin receptor activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006407	rRNA export from nucleus	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006458	'de novo' protein folding	1.66e-03	1.00e+00	9.231	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	1.66e-03	1.00e+00	9.231	1	2	3
GO:0030135	coated vesicle	1.66e-03	1.00e+00	9.231	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.66e-03	1.00e+00	9.231	1	1	3
GO:0006511	ubiquitin-dependent protein catabolic process	2.05e-03	1.00e+00	4.839	2	5	126
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.22e-03	1.00e+00	8.816	1	1	4
GO:0030686	90S preribosome	2.22e-03	1.00e+00	8.816	1	1	4
GO:0004839	ubiquitin activating enzyme activity	2.22e-03	1.00e+00	8.816	1	1	4
GO:0016032	viral process	2.46e-03	1.00e+00	3.340	3	55	534
GO:0043248	proteasome assembly	2.77e-03	1.00e+00	8.494	1	1	5
GO:0046696	lipopolysaccharide receptor complex	2.77e-03	1.00e+00	8.494	1	1	5
GO:0006102	isocitrate metabolic process	2.77e-03	1.00e+00	8.494	1	1	5
GO:0019941	modification-dependent protein catabolic process	2.77e-03	1.00e+00	8.494	1	1	5
GO:0003688	DNA replication origin binding	3.32e-03	1.00e+00	8.231	1	2	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	3.32e-03	1.00e+00	8.231	1	1	6
GO:0006101	citrate metabolic process	3.32e-03	1.00e+00	8.231	1	1	6
GO:0005524	ATP binding	3.40e-03	1.00e+00	2.474	4	60	1298
GO:0033180	proton-transporting V-type ATPase, V1 domain	3.88e-03	1.00e+00	8.009	1	2	7
GO:0030867	rough endoplasmic reticulum membrane	3.88e-03	1.00e+00	8.009	1	2	7
GO:0000028	ribosomal small subunit assembly	3.88e-03	1.00e+00	8.009	1	1	7
GO:0051604	protein maturation	4.43e-03	1.00e+00	7.816	1	1	8
GO:0005765	lysosomal membrane	5.22e-03	1.00e+00	4.151	2	5	203
GO:0006098	pentose-phosphate shunt	5.53e-03	1.00e+00	7.494	1	4	10
GO:0043032	positive regulation of macrophage activation	5.53e-03	1.00e+00	7.494	1	1	10
GO:0032727	positive regulation of interferon-alpha production	6.09e-03	1.00e+00	7.357	1	1	11
GO:0016071	mRNA metabolic process	6.27e-03	1.00e+00	4.015	2	31	223
GO:0005759	mitochondrial matrix	6.54e-03	1.00e+00	3.983	2	14	228
GO:0005838	proteasome regulatory particle	6.64e-03	1.00e+00	7.231	1	7	12
GO:0001530	lipopolysaccharide binding	7.19e-03	1.00e+00	7.116	1	3	13
GO:0051131	chaperone-mediated protein complex assembly	7.19e-03	1.00e+00	7.116	1	1	13
GO:0016070	RNA metabolic process	7.64e-03	1.00e+00	3.868	2	32	247
GO:0004842	ubiquitin-protein transferase activity	8.13e-03	1.00e+00	3.822	2	6	255
GO:0046961	proton-transporting ATPase activity, rotational mechanism	8.29e-03	1.00e+00	6.909	1	3	15
GO:0042026	protein refolding	8.29e-03	1.00e+00	6.909	1	2	15
GO:0046034	ATP metabolic process	8.29e-03	1.00e+00	6.909	1	1	15
GO:0050870	positive regulation of T cell activation	9.39e-03	1.00e+00	6.729	1	1	17
GO:0022624	proteasome accessory complex	9.39e-03	1.00e+00	6.729	1	8	17
GO:0015078	hydrogen ion transmembrane transporter activity	1.05e-02	1.00e+00	6.568	1	3	19
GO:0032733	positive regulation of interleukin-10 production	1.05e-02	1.00e+00	6.568	1	1	19
GO:0048863	stem cell differentiation	1.05e-02	1.00e+00	6.568	1	1	19
GO:0042100	B cell proliferation	1.16e-02	1.00e+00	6.424	1	1	21
GO:0000792	heterochromatin	1.21e-02	1.00e+00	6.357	1	2	22
GO:0030057	desmosome	1.27e-02	1.00e+00	6.293	1	1	23
GO:0043236	laminin binding	1.27e-02	1.00e+00	6.293	1	1	23
GO:0042113	B cell activation	1.38e-02	1.00e+00	6.172	1	2	25
GO:0032735	positive regulation of interleukin-12 production	1.38e-02	1.00e+00	6.172	1	1	25
GO:0005739	mitochondrion	1.42e-02	1.00e+00	2.438	3	28	998
GO:0070979	protein K11-linked ubiquitination	1.43e-02	1.00e+00	6.116	1	6	26
GO:0015991	ATP hydrolysis coupled proton transport	1.43e-02	1.00e+00	6.116	1	4	26
GO:0043022	ribosome binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0050661	NADP binding	1.49e-02	1.00e+00	6.061	1	2	27
GO:0006099	tricarboxylic acid cycle	1.54e-02	1.00e+00	6.009	1	4	28
GO:0015992	proton transport	1.60e-02	1.00e+00	5.958	1	3	29
GO:0033572	transferrin transport	1.65e-02	1.00e+00	5.909	1	5	30
GO:0044822	poly(A) RNA binding	1.66e-02	1.00e+00	2.357	3	49	1056
GO:0051701	interaction with host	1.76e-02	1.00e+00	5.816	1	4	32
GO:0051539	4 iron, 4 sulfur cluster binding	1.93e-02	1.00e+00	5.687	1	3	35
GO:0090382	phagosome maturation	1.98e-02	1.00e+00	5.646	1	5	36
GO:0032755	positive regulation of interleukin-6 production	1.98e-02	1.00e+00	5.646	1	2	36
GO:0016881	acid-amino acid ligase activity	2.03e-02	1.00e+00	5.607	1	2	37
GO:0005902	microvillus	2.09e-02	1.00e+00	5.568	1	2	38
GO:0032729	positive regulation of interferon-gamma production	2.14e-02	1.00e+00	5.531	1	2	39
GO:0022627	cytosolic small ribosomal subunit	2.14e-02	1.00e+00	5.531	1	4	39
GO:0043066	negative regulation of apoptotic process	2.15e-02	1.00e+00	3.088	2	31	424
GO:0042110	T cell activation	2.31e-02	1.00e+00	5.424	1	3	42
GO:0044281	small molecule metabolic process	2.40e-02	1.00e+00	2.159	3	58	1211
GO:0070936	protein K48-linked ubiquitination	2.42e-02	1.00e+00	5.357	1	2	44
GO:0006091	generation of precursor metabolites and energy	2.74e-02	1.00e+00	5.172	1	3	50
GO:0006521	regulation of cellular amino acid metabolic process	2.74e-02	1.00e+00	5.172	1	17	50
GO:0006986	response to unfolded protein	2.74e-02	1.00e+00	5.172	1	2	50
GO:0005905	coated pit	2.74e-02	1.00e+00	5.172	1	3	50
GO:0006879	cellular iron ion homeostasis	2.79e-02	1.00e+00	5.144	1	4	51
GO:0003725	double-stranded RNA binding	2.85e-02	1.00e+00	5.116	1	5	52
GO:0002039	p53 binding	3.01e-02	1.00e+00	5.035	1	7	55
GO:0012505	endomembrane system	3.06e-02	1.00e+00	5.009	1	2	56
GO:0000502	proteasome complex	3.17e-02	1.00e+00	4.958	1	17	58
GO:0051087	chaperone binding	3.23e-02	1.00e+00	4.933	1	6	59
GO:0030141	secretory granule	3.39e-02	1.00e+00	4.862	1	2	62
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.50e-02	1.00e+00	4.816	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.55e-02	1.00e+00	4.794	1	22	65
GO:0003697	single-stranded DNA binding	3.71e-02	1.00e+00	4.729	1	5	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.82e-02	1.00e+00	4.687	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.93e-02	1.00e+00	4.646	1	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.03e-02	1.00e+00	4.607	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.09e-02	1.00e+00	4.587	1	20	75
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	4.19e-02	1.00e+00	4.549	1	7	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.30e-02	1.00e+00	4.512	1	23	79
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	4.35e-02	1.00e+00	4.494	1	3	80
GO:0001726	ruffle	4.35e-02	1.00e+00	4.494	1	4	80
GO:0019083	viral transcription	4.41e-02	1.00e+00	4.476	1	10	81
GO:0006415	translational termination	4.73e-02	1.00e+00	4.373	1	10	87
GO:0050821	protein stabilization	4.78e-02	1.00e+00	4.357	1	2	88
GO:0042470	melanosome	4.94e-02	1.00e+00	4.308	1	9	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.99e-02	1.00e+00	4.293	1	21	92
GO:0010467	gene expression	4.99e-02	1.00e+00	2.430	2	59	669
GO:0006414	translational elongation	5.04e-02	1.00e+00	4.277	1	13	93
GO:0051082	unfolded protein binding	5.04e-02	1.00e+00	4.277	1	5	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.63e-02	1.00e+00	4.116	1	10	104
GO:0016020	membrane	5.64e-02	1.00e+00	1.686	3	90	1681
GO:0005506	iron ion binding	5.68e-02	1.00e+00	4.102	1	4	105
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.15e-02	1.00e+00	3.983	1	11	114
GO:0019058	viral life cycle	6.20e-02	1.00e+00	3.971	1	13	115
GO:0000209	protein polyubiquitination	6.26e-02	1.00e+00	3.958	1	20	116
GO:0044237	cellular metabolic process	6.31e-02	1.00e+00	3.946	1	5	117
GO:0006413	translational initiation	7.04e-02	1.00e+00	3.783	1	17	131
GO:0005634	nucleus	7.14e-02	1.00e+00	0.984	5	136	4559
GO:0003735	structural constituent of ribosome	7.35e-02	1.00e+00	3.718	1	10	137
GO:0016887	ATPase activity	7.51e-02	1.00e+00	3.687	1	7	140
GO:0008286	insulin receptor signaling pathway	7.61e-02	1.00e+00	3.666	1	7	142
GO:0000082	G1/S transition of mitotic cell cycle	7.97e-02	1.00e+00	3.597	1	32	149
GO:0042981	regulation of apoptotic process	8.03e-02	1.00e+00	3.587	1	24	150
GO:0010008	endosome membrane	8.08e-02	1.00e+00	3.578	1	7	151
GO:0006974	cellular response to DNA damage stimulus	8.08e-02	1.00e+00	3.578	1	8	151
GO:0005769	early endosome	8.13e-02	1.00e+00	3.568	1	2	152
GO:0034641	cellular nitrogen compound metabolic process	9.10e-02	1.00e+00	3.398	1	20	171
GO:0006412	translation	1.21e-01	1.00e+00	2.971	1	20	230
GO:0005975	carbohydrate metabolic process	1.32e-01	1.00e+00	2.833	1	9	253
GO:0043065	positive regulation of apoptotic process	1.39e-01	1.00e+00	2.750	1	10	268
GO:0005743	mitochondrial inner membrane	1.44e-01	1.00e+00	2.702	1	8	277
GO:0006200	ATP catabolic process	1.51e-01	1.00e+00	2.626	1	15	292
GO:0043234	protein complex	1.52e-01	1.00e+00	2.612	1	18	295
GO:0016567	protein ubiquitination	1.52e-01	1.00e+00	2.612	1	5	295
GO:0005886	plasma membrane	1.59e-01	1.00e+00	1.067	3	45	2582
GO:0043231	intracellular membrane-bounded organelle	1.63e-01	1.00e+00	2.503	1	9	318
GO:0007155	cell adhesion	1.87e-01	1.00e+00	2.289	1	6	369
GO:0000278	mitotic cell cycle	1.97e-01	1.00e+00	2.205	1	48	391
GO:0005515	protein binding	2.02e-01	1.00e+00	0.582	5	184	6024
GO:0009986	cell surface	2.02e-01	1.00e+00	2.165	1	11	402
GO:0055114	oxidation-reduction process	2.11e-01	1.00e+00	2.102	1	12	420
GO:0055085	transmembrane transport	2.17e-01	1.00e+00	2.051	1	10	435
GO:0044267	cellular protein metabolic process	2.35e-01	1.00e+00	1.927	1	29	474
GO:0006915	apoptotic process	2.69e-01	1.00e+00	1.700	1	33	555
GO:0005737	cytoplasm	3.49e-01	1.00e+00	0.522	3	110	3767
GO:0005615	extracellular space	4.23e-01	1.00e+00	0.914	1	17	957
GO:0005654	nucleoplasm	4.64e-01	1.00e+00	0.737	1	76	1082
GO:0016021	integral component of membrane	6.94e-01	1.00e+00	-0.137	1	27	1982

Wolf-ratios-Mammosphere-Adherent

int-snw-7328

Statistics

Genes (8)

Interactions (13)

Related GO terms (148)