int-snw-6598

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.956	2.37e-16	1.54e-03	2.84e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-6598 subnetwork

Genes (12)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPS11	6205	36	0.993	1.113	175	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
RPL6	6128	11	0.844	1.113	164	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
SAP18	10284	8	1.115	1.069	57	Yes	-
OGDH	4967	13	0.847	1.076	113	Yes	-
RAN	5901	5	0.632	0.994	175	Yes	-
PSMD6	9861	11	0.848	1.009	131	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
RPS3A	6189	11	0.835	1.069	166	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-
[ SMARCB1 ]	6598	1	0.433	0.956	117	-	-

Interactions (23)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
OGDH	4967	PSMD6	9861	pp	--	int.I2D: YeastLow
OGDH	4967	PGD	5226	pp	--	int.I2D: YeastLow
RPL6	6128	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RAN	5901	RPS11	6205	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RAN	5901	SMARCB1	6598	pp	--	int.I2D: BioGrid
ACTB	60	RPS3A	6189	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPL6	6128	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPS3A	6189	PSMD6	9861	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPSA	3921	RAN	5901	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
RPS3A	6189	SAP18	10284	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, MINT; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
PGD	5226	RAN	5901	pp	--	int.I2D: YeastLow
RPS3A	6189	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RAN	5901	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE
RPL6	6128	RPS3A	6189	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	RAN	5901	pp	--	int.I2D: YeastLow
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
ACTB	60	RPL6	6128	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPS3A	6189	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD6	9861	pp	--	int.I2D: BioGrid_Yeast
OGDH	4967	RPL6	6128	pp	--	int.I2D: IntAct_Yeast
RPS3A	6189	SMARCB1	6598	pp	--	int.I2D: IntAct_Fly, BioGrid_Fly, BIND_Fly, FlyEmbryo, FlyLow, MINT_Fly

Related GO terms (192)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0019058	viral life cycle	2.00e-10	2.89e-06	5.971	6	13	115
GO:0019083	viral transcription	3.79e-09	5.46e-05	6.213	5	10	81
GO:0006415	translational termination	5.45e-09	7.86e-05	6.110	5	10	87
GO:0006414	translational elongation	7.64e-09	1.10e-04	6.014	5	13	93
GO:0016071	mRNA metabolic process	1.09e-08	1.58e-04	5.015	6	31	223
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.35e-08	1.94e-04	5.853	5	10	104
GO:0016070	RNA metabolic process	2.01e-08	2.90e-04	4.868	6	32	247
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.14e-08	3.09e-04	5.720	5	11	114
GO:0006413	translational initiation	4.31e-08	6.21e-04	5.520	5	17	131
GO:0003735	structural constituent of ribosome	5.40e-08	7.78e-04	5.455	5	10	137
GO:0016032	viral process	6.18e-08	8.92e-04	3.978	7	55	534
GO:0010467	gene expression	2.89e-07	4.17e-03	3.653	7	59	669
GO:0006412	translation	7.14e-07	1.03e-02	4.708	5	20	230
GO:0044267	cellular protein metabolic process	9.53e-07	1.37e-02	3.927	6	29	474
GO:0022627	cytosolic small ribosomal subunit	3.95e-06	5.70e-02	6.531	3	4	39
GO:0044822	poly(A) RNA binding	6.32e-06	9.11e-02	2.994	7	49	1056
GO:0030957	Tat protein binding	9.50e-06	1.37e-01	8.646	2	3	6
GO:0005829	cytosol	1.83e-05	2.63e-01	2.116	9	132	2496
GO:0036464	cytoplasmic ribonucleoprotein granule	1.45e-04	1.00e+00	6.772	2	4	22
GO:0070062	extracellular vesicular exosome	1.53e-04	1.00e+00	2.002	8	104	2400
GO:0043044	ATP-dependent chromatin remodeling	1.59e-04	1.00e+00	6.708	2	4	23
GO:0005925	focal adhesion	1.72e-04	1.00e+00	3.715	4	19	366
GO:0031492	nucleosomal DNA binding	2.20e-04	1.00e+00	6.476	2	4	27
GO:0022625	cytosolic large ribosomal subunit	7.30e-04	1.00e+00	5.616	2	6	49
GO:0044772	mitotic cell cycle phase transition	8.32e-04	1.00e+00	10.231	1	1	1
GO:0019521	D-gluconate metabolic process	8.32e-04	1.00e+00	10.231	1	1	1
GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	8.32e-04	1.00e+00	10.231	1	1	1
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	8.54e-04	1.00e+00	5.503	2	5	53
GO:0016020	membrane	1.23e-03	1.00e+00	2.101	6	90	1681
GO:0061034	olfactory bulb mitral cell layer development	1.66e-03	1.00e+00	9.231	1	1	2
GO:0045252	oxoglutarate dehydrogenase complex	1.66e-03	1.00e+00	9.231	1	2	2
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	1.66e-03	1.00e+00	9.231	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.66e-03	1.00e+00	9.231	1	1	2
GO:0019322	pentose biosynthetic process	1.66e-03	1.00e+00	9.231	1	2	2
GO:0005055	laminin receptor activity	1.66e-03	1.00e+00	9.231	1	1	2
GO:0006407	rRNA export from nucleus	1.66e-03	1.00e+00	9.231	1	1	2
GO:0003723	RNA binding	2.48e-03	1.00e+00	3.398	3	20	342
GO:0061574	ASAP complex	2.49e-03	1.00e+00	8.646	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	2.49e-03	1.00e+00	8.646	1	1	3
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	2.49e-03	1.00e+00	8.646	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	2.49e-03	1.00e+00	8.646	1	2	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	2.49e-03	1.00e+00	8.646	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	2.49e-03	1.00e+00	8.646	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3.32e-03	1.00e+00	8.231	1	1	4
GO:0030686	90S preribosome	3.32e-03	1.00e+00	8.231	1	1	4
GO:0006104	succinyl-CoA metabolic process	3.32e-03	1.00e+00	8.231	1	1	4
GO:0001835	blastocyst hatching	3.32e-03	1.00e+00	8.231	1	2	4
GO:0000055	ribosomal large subunit export from nucleus	3.32e-03	1.00e+00	8.231	1	1	4
GO:0006734	NADH metabolic process	3.32e-03	1.00e+00	8.231	1	1	4
GO:0030529	ribonucleoprotein complex	3.75e-03	1.00e+00	4.424	2	8	112
GO:0030976	thiamine pyrophosphate binding	4.15e-03	1.00e+00	7.909	1	1	5
GO:0000790	nuclear chromatin	4.94e-03	1.00e+00	4.220	2	9	129
GO:0002181	cytoplasmic translation	4.98e-03	1.00e+00	7.646	1	1	6
GO:0021695	cerebellar cortex development	4.98e-03	1.00e+00	7.646	1	2	6
GO:0021860	pyramidal neuron development	4.98e-03	1.00e+00	7.646	1	1	6
GO:0015074	DNA integration	5.81e-03	1.00e+00	7.424	1	1	7
GO:0000028	ribosomal small subunit assembly	5.81e-03	1.00e+00	7.424	1	1	7
GO:0070688	MLL5-L complex	6.64e-03	1.00e+00	7.231	1	1	8
GO:0006554	lysine catabolic process	6.64e-03	1.00e+00	7.231	1	2	8
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	7.96e-03	1.00e+00	3.865	2	7	165
GO:0006098	pentose-phosphate shunt	8.29e-03	1.00e+00	6.909	1	4	10
GO:0021756	striatum development	8.29e-03	1.00e+00	6.909	1	1	10
GO:0034641	cellular nitrogen compound metabolic process	8.53e-03	1.00e+00	3.813	2	20	171
GO:0043923	positive regulation by host of viral transcription	9.12e-03	1.00e+00	6.772	1	2	11
GO:0021794	thalamus development	9.12e-03	1.00e+00	6.772	1	1	11
GO:0071564	npBAF complex	9.12e-03	1.00e+00	6.772	1	3	11
GO:0005654	nucleoplasm	9.57e-03	1.00e+00	2.152	4	76	1082
GO:0001741	XY body	9.94e-03	1.00e+00	6.646	1	1	12
GO:0071565	nBAF complex	9.94e-03	1.00e+00	6.646	1	3	12
GO:0042273	ribosomal large subunit biogenesis	1.08e-02	1.00e+00	6.531	1	4	13
GO:0035267	NuA4 histone acetyltransferase complex	1.16e-02	1.00e+00	6.424	1	4	14
GO:0016514	SWI/SNF complex	1.24e-02	1.00e+00	6.324	1	3	15
GO:0048025	negative regulation of mRNA splicing, via spliceosome	1.24e-02	1.00e+00	6.324	1	1	15
GO:0050998	nitric-oxide synthase binding	1.32e-02	1.00e+00	6.231	1	1	16
GO:0006103	2-oxoglutarate metabolic process	1.32e-02	1.00e+00	6.231	1	1	16
GO:0075733	intracellular transport of virus	1.41e-02	1.00e+00	6.144	1	3	17
GO:0006337	nucleosome disassembly	1.41e-02	1.00e+00	6.144	1	3	17
GO:0022624	proteasome accessory complex	1.41e-02	1.00e+00	6.144	1	8	17
GO:0044281	small molecule metabolic process	1.42e-02	1.00e+00	1.989	4	58	1211
GO:0035145	exon-exon junction complex	1.57e-02	1.00e+00	5.983	1	1	19
GO:0006259	DNA metabolic process	1.57e-02	1.00e+00	5.983	1	2	19
GO:0003713	transcription coactivator activity	1.59e-02	1.00e+00	3.342	2	10	237
GO:0030863	cortical cytoskeleton	1.82e-02	1.00e+00	5.772	1	1	22
GO:0007052	mitotic spindle organization	1.82e-02	1.00e+00	5.772	1	2	22
GO:0043236	laminin binding	1.90e-02	1.00e+00	5.708	1	1	23
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.95e-02	1.00e+00	3.187	2	8	264
GO:0006611	protein export from nucleus	2.06e-02	1.00e+00	5.587	1	3	25
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	2.14e-02	1.00e+00	5.531	1	1	26
GO:0019843	rRNA binding	2.22e-02	1.00e+00	5.476	1	3	27
GO:0043022	ribosome binding	2.22e-02	1.00e+00	5.476	1	3	27
GO:0050661	NADP binding	2.22e-02	1.00e+00	5.476	1	2	27
GO:0006099	tricarboxylic acid cycle	2.31e-02	1.00e+00	5.424	1	4	28
GO:0000118	histone deacetylase complex	2.31e-02	1.00e+00	5.424	1	1	28
GO:0019894	kinesin binding	2.31e-02	1.00e+00	5.424	1	1	28
GO:0043234	protein complex	2.40e-02	1.00e+00	3.027	2	18	295
GO:0030154	cell differentiation	2.50e-02	1.00e+00	2.998	2	5	301
GO:1903507	negative regulation of nucleic acid-templated transcription	2.63e-02	1.00e+00	5.231	1	2	32
GO:0031072	heat shock protein binding	2.71e-02	1.00e+00	5.187	1	1	33
GO:0001895	retina homeostasis	2.79e-02	1.00e+00	5.144	1	1	34
GO:0034332	adherens junction organization	2.96e-02	1.00e+00	5.061	1	1	36
GO:0051084	'de novo' posttranslational protein folding	3.04e-02	1.00e+00	5.022	1	4	37
GO:0021766	hippocampus development	3.12e-02	1.00e+00	4.983	1	4	38
GO:0006096	glycolytic process	3.12e-02	1.00e+00	4.983	1	4	38
GO:0032092	positive regulation of protein binding	3.12e-02	1.00e+00	4.983	1	3	38
GO:0070527	platelet aggregation	3.12e-02	1.00e+00	4.983	1	2	38
GO:0050681	androgen receptor binding	3.12e-02	1.00e+00	4.983	1	3	38
GO:0007286	spermatid development	3.36e-02	1.00e+00	4.874	1	1	41
GO:0030521	androgen receptor signaling pathway	3.36e-02	1.00e+00	4.874	1	1	41
GO:0021762	substantia nigra development	3.60e-02	1.00e+00	4.772	1	2	44
GO:0019003	GDP binding	3.84e-02	1.00e+00	4.677	1	2	47
GO:0006091	generation of precursor metabolites and energy	4.08e-02	1.00e+00	4.587	1	3	50
GO:0006521	regulation of cellular amino acid metabolic process	4.08e-02	1.00e+00	4.587	1	17	50
GO:0045216	cell-cell junction organization	4.40e-02	1.00e+00	4.476	1	2	54
GO:0031966	mitochondrial membrane	4.48e-02	1.00e+00	4.450	1	1	55
GO:0002039	p53 binding	4.48e-02	1.00e+00	4.450	1	7	55
GO:0005643	nuclear pore	4.64e-02	1.00e+00	4.398	1	4	57
GO:0043066	negative regulation of apoptotic process	4.68e-02	1.00e+00	2.503	2	31	424
GO:0005840	ribosome	4.72e-02	1.00e+00	4.373	1	1	58
GO:0000502	proteasome complex	4.72e-02	1.00e+00	4.373	1	17	58
GO:0051087	chaperone binding	4.80e-02	1.00e+00	4.348	1	6	59
GO:0005634	nucleus	5.06e-02	1.00e+00	0.884	7	136	4559
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.20e-02	1.00e+00	4.231	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.28e-02	1.00e+00	4.209	1	22	65
GO:0006338	chromatin remodeling	5.36e-02	1.00e+00	4.187	1	5	66
GO:0034329	cell junction assembly	5.52e-02	1.00e+00	4.144	1	1	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.67e-02	1.00e+00	4.102	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	5.83e-02	1.00e+00	4.061	1	20	72
GO:0000785	chromatin	5.91e-02	1.00e+00	4.041	1	4	73
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	5.99e-02	1.00e+00	4.022	1	6	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.99e-02	1.00e+00	4.022	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.07e-02	1.00e+00	4.002	1	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.38e-02	1.00e+00	3.927	1	23	79
GO:0005737	cytoplasm	6.58e-02	1.00e+00	0.937	6	110	3767
GO:0042470	melanosome	7.32e-02	1.00e+00	3.723	1	9	91
GO:0006928	cellular component movement	7.32e-02	1.00e+00	3.723	1	7	91
GO:0005200	structural constituent of cytoskeleton	7.32e-02	1.00e+00	3.723	1	8	91
GO:0005515	protein binding	7.35e-02	1.00e+00	0.675	8	184	6024
GO:0001649	osteoblast differentiation	7.39e-02	1.00e+00	3.708	1	6	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	7.39e-02	1.00e+00	3.708	1	5	92
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.39e-02	1.00e+00	3.708	1	21	92
GO:0006364	rRNA processing	7.55e-02	1.00e+00	3.677	1	6	94
GO:0014069	postsynaptic density	8.40e-02	1.00e+00	3.517	1	3	105
GO:0072562	blood microparticle	8.86e-02	1.00e+00	3.437	1	3	111
GO:0000209	protein polyubiquitination	9.24e-02	1.00e+00	3.373	1	20	116
GO:0044237	cellular metabolic process	9.32e-02	1.00e+00	3.361	1	5	117
GO:0006325	chromatin organization	9.39e-02	1.00e+00	3.348	1	5	118
GO:0016887	ATPase activity	1.10e-01	1.00e+00	3.102	1	7	140
GO:0006457	protein folding	1.13e-01	1.00e+00	3.071	1	7	143
GO:0061024	membrane organization	1.14e-01	1.00e+00	3.051	1	7	145
GO:0000082	G1/S transition of mitotic cell cycle	1.17e-01	1.00e+00	3.012	1	32	149
GO:0042981	regulation of apoptotic process	1.18e-01	1.00e+00	3.002	1	24	150
GO:0006397	mRNA processing	1.25e-01	1.00e+00	2.909	1	2	160
GO:0030424	axon	1.30e-01	1.00e+00	2.856	1	4	166
GO:0016607	nuclear speck	1.34e-01	1.00e+00	2.805	1	3	172
GO:0003714	transcription corepressor activity	1.38e-01	1.00e+00	2.755	1	8	178
GO:0019904	protein domain specific binding	1.39e-01	1.00e+00	2.747	1	6	179
GO:0005730	nucleolus	1.48e-01	1.00e+00	1.136	3	69	1641
GO:0003924	GTPase activity	1.52e-01	1.00e+00	2.609	1	12	197
GO:0006184	GTP catabolic process	1.64e-01	1.00e+00	2.490	1	12	214
GO:0007067	mitotic nuclear division	1.73e-01	1.00e+00	2.405	1	14	227
GO:0008380	RNA splicing	1.74e-01	1.00e+00	2.398	1	11	228
GO:0005759	mitochondrial matrix	1.74e-01	1.00e+00	2.398	1	14	228
GO:0007399	nervous system development	1.76e-01	1.00e+00	2.379	1	5	231
GO:0005975	carbohydrate metabolic process	1.91e-01	1.00e+00	2.248	1	9	253
GO:0006281	DNA repair	1.97e-01	1.00e+00	2.203	1	18	261
GO:0043065	positive regulation of apoptotic process	2.02e-01	1.00e+00	2.165	1	10	268
GO:0007264	small GTPase mediated signal transduction	2.09e-01	1.00e+00	2.107	1	4	279
GO:0005856	cytoskeleton	2.17e-01	1.00e+00	2.046	1	12	291
GO:0006200	ATP catabolic process	2.18e-01	1.00e+00	2.041	1	15	292
GO:0005525	GTP binding	2.30e-01	1.00e+00	1.955	1	12	310
GO:0019901	protein kinase binding	2.34e-01	1.00e+00	1.923	1	21	317
GO:0007411	axon guidance	2.35e-01	1.00e+00	1.914	1	13	319
GO:0003682	chromatin binding	2.41e-01	1.00e+00	1.878	1	11	327
GO:0008285	negative regulation of cell proliferation	2.57e-01	1.00e+00	1.768	1	11	353
GO:0007155	cell adhesion	2.67e-01	1.00e+00	1.704	1	6	369
GO:0006508	proteolysis	2.73e-01	1.00e+00	1.669	1	9	378
GO:0000278	mitotic cell cycle	2.81e-01	1.00e+00	1.620	1	48	391
GO:0055114	oxidation-reduction process	2.99e-01	1.00e+00	1.517	1	12	420
GO:0007596	blood coagulation	3.19e-01	1.00e+00	1.401	1	18	455
GO:0045893	positive regulation of transcription, DNA-templated	3.33e-01	1.00e+00	1.330	1	13	478
GO:0006351	transcription, DNA-templated	3.42e-01	1.00e+00	0.733	2	31	1446
GO:0006915	apoptotic process	3.76e-01	1.00e+00	1.115	1	33	555
GO:0045087	innate immune response	3.97e-01	1.00e+00	1.012	1	24	596
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.91e-01	1.00e+00	0.607	1	19	789
GO:0007165	signal transduction	5.41e-01	1.00e+00	0.406	1	24	907
GO:0005615	extracellular space	5.61e-01	1.00e+00	0.329	1	17	957
GO:0005739	mitochondrion	5.77e-01	1.00e+00	0.268	1	28	998
GO:0006355	regulation of transcription, DNA-templated	5.77e-01	1.00e+00	0.270	1	18	997
GO:0003677	DNA binding	6.53e-01	1.00e+00	-0.019	1	28	1218
GO:0005524	ATP binding	6.78e-01	1.00e+00	-0.111	1	60	1298
GO:0046872	metal ion binding	6.80e-01	1.00e+00	-0.121	1	25	1307
GO:0005886	plasma membrane	9.06e-01	1.00e+00	-1.103	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-6598

Statistics

Genes (12)

Interactions (23)

Related GO terms (192)