int-snw-5713
Statistics
| Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
|---|---|---|---|---|
| wolf-screen-ratio-mammosphere-adherent | 0.933 | 1.88e-15 | 2.56e-03 | 4.11e-02 |
Genes (17)
| Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
|---|---|---|---|---|---|---|---|
| PSMB4 | 5692 | 1 | 0.748 | 0.933 | 69 | Yes | - |
| RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
| PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
| PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
| [ PSMD7 ] | 5713 | 5 | 0.640 | 0.958 | 133 | Yes | - |
| PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
| OGDH | 4967 | 13 | 0.847 | 1.076 | 113 | Yes | - |
| ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
| PSMD1 | 5707 | 12 | 0.836 | 1.057 | 113 | Yes | - |
| PSMD13 | 5719 | 16 | 0.848 | 1.029 | 104 | Yes | - |
| EEF2 | 1938 | 27 | 0.890 | 1.043 | 301 | Yes | - |
| PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
| PSMB2 | 5690 | 18 | 0.877 | 1.026 | 117 | Yes | - |
| ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
| PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
| PSMD6 | 9861 | 11 | 0.848 | 1.009 | 131 | Yes | - |
| PSMC1 | 5700 | 14 | 0.840 | 1.018 | 137 | Yes | - |
Interactions (89)
| Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
|---|---|---|---|---|---|---|
| PSMC1 | 5700 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, BioGrid, IntAct_Yeast, Krogan_Core, YeastHigh |
| PSMA2 | 5683 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMA1 | 5682 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastMedium |
| PSMB4 | 5692 | PSMD6 | 9861 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA2 | 5683 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA1 | 5682 | PSMC1 | 5700 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Fly, YeastMedium, IntAct |
| PSMD1 | 5707 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, MINT_Yeast, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core |
| PSMB2 | 5690 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA2 | 5683 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Fly, YeastLow |
| PSMD7 | 5713 | PSMD11 | 5717 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, IntAct |
| PSMB2 | 5690 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
| OGDH | 4967 | PSMD7 | 5713 | pp | -- | int.I2D: YeastLow |
| PSMB4 | 5692 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow, IntAct_Yeast, MINT_Yeast |
| PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMC1 | 5700 | PSMD1 | 5707 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, Krogan_Core, MINT_Yeast |
| PSMB7 | 5695 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast |
| OGDH | 4967 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
| PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
| PSMA1 | 5682 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast |
| ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| PSMB7 | 5695 | PSMD1 | 5707 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct |
| EEF2 | 1938 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
| PSMC1 | 5700 | PSMD7 | 5713 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, MINT_Yeast, YeastHigh, BCI, BioGrid_Yeast, HPRD, Krogan_Core; int.HPRD: in vitro |
| PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
| PSMC1 | 5700 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
| PSMA2 | 5683 | PSMB4 | 5692 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastMedium, Krogan_Core |
| ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMD13 | 5719 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Krogan_Core |
| ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMC1 | 5700 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, BioGrid, IntAct_Yeast, Krogan_Core |
| PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
| ACO2 | 50 | OGDH | 4967 | pp | -- | int.I2D: YeastLow |
| PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMB7 | 5695 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMB4 | 5692 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMB2 | 5690 | PSMD6 | 9861 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMA1 | 5682 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
| ACTB | 60 | PSMD6 | 9861 | pp | -- | int.I2D: BioGrid_Yeast |
| OGDH | 4967 | PSMD6 | 9861 | pp | -- | int.I2D: YeastLow |
| PSMD3 | 5709 | PSMD13 | 5719 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core |
| ACO2 | 50 | PSMD7 | 5713 | pp | -- | int.I2D: YeastLow |
| PSMD7 | 5713 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
| PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
| PSMB7 | 5695 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct |
| PSMD1 | 5707 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast |
| OGDH | 4967 | PSMC1 | 5700 | pp | -- | int.I2D: YeastLow |
| PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
| ACO2 | 50 | PSMC1 | 5700 | pp | -- | int.I2D: YeastLow |
| PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMB2 | 5690 | PSMB4 | 5692 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, BIND_Yeast, Krogan_Core, YeastLow, Yu_GoldStd |
| PSMB2 | 5690 | PSMD13 | 5719 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| PSMB4 | 5692 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| PSMB4 | 5692 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
| PSMA1 | 5682 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium, IntAct_Yeast, MINT_Yeast |
| PSMA2 | 5683 | PSMD13 | 5719 | pp | -- | int.I2D: YeastLow |
| PSMD1 | 5707 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, IntAct, Krogan_Core |
| PSMD7 | 5713 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, IntAct_Fly, Krogan_Core, Tarassov_PCA |
| ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
| OGDH | 4967 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
| PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
| OGDH | 4967 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
| PSMC1 | 5700 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, MINT_Yeast, YeastHigh, Krogan_Core |
| PSMA1 | 5682 | PSMB4 | 5692 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastMedium, Krogan_Core, MINT_Yeast, Yu_GoldStd |
| PSMD1 | 5707 | PSMD7 | 5713 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, Krogan_Core |
| ACTB | 60 | PSMD13 | 5719 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMB4 | 5692 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| PSMD11 | 5717 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, INTEROLOG |
| PSMD7 | 5713 | RBX1 | 9978 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast |
| PSMD11 | 5717 | PSMD13 | 5719 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, INTEROLOG |
| PSMA2 | 5683 | PSMD6 | 9861 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct, YeastLow, BioGrid |
| PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
| ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
| PSMB4 | 5692 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT, MINT_Yeast, YeastLow, Yu_GoldStd; int.Mint: MI:0915(physical association) |
| PSMD3 | 5709 | PSMD6 | 9861 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, IntAct, IntAct_Yeast, MINT_Worm, MINT_Yeast, YeastHigh, BioGrid, BIND_Yeast, IntAct_Worm, INTEROLOG, Krogan_Core, MIPS |
| PSMB2 | 5690 | PSMC1 | 5700 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
| PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
| PSMD3 | 5709 | PSMD7 | 5713 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct |
| ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
| PSMD1 | 5707 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core |
| EEF2 | 1938 | PSMD7 | 5713 | pp | -- | int.I2D: YeastLow |
| ACTB | 60 | EEF2 | 1938 | pp | -- | int.I2D: YeastLow, IntAct_Yeast |
| EEF2 | 1938 | PSMD3 | 5709 | pp | -- | int.I2D: Krogan_NonCore |
Related GO terms (160)
| Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
|---|---|---|---|---|---|---|---|
| GO:0006521 | regulation of cellular amino acid metabolic process | 4.41e-27 | 6.36e-23 | 7.670 | 12 | 17 | 50 |
| GO:0000502 | proteasome complex | 3.23e-26 | 4.66e-22 | 7.456 | 12 | 17 | 58 |
| GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 1.19e-25 | 1.71e-21 | 7.314 | 12 | 19 | 64 |
| GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.46e-25 | 2.10e-21 | 7.291 | 12 | 22 | 65 |
| GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.84e-25 | 5.53e-21 | 7.184 | 12 | 22 | 70 |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 5.54e-25 | 7.99e-21 | 7.144 | 12 | 20 | 72 |
| GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.90e-25 | 1.14e-20 | 7.104 | 12 | 22 | 74 |
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 9.41e-25 | 1.36e-20 | 7.085 | 12 | 20 | 75 |
| GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.84e-24 | 2.66e-20 | 7.010 | 12 | 23 | 79 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.30e-23 | 1.87e-19 | 6.790 | 12 | 21 | 92 |
| GO:0034641 | cellular nitrogen compound metabolic process | 1.32e-22 | 1.90e-18 | 6.011 | 13 | 20 | 171 |
| GO:0000209 | protein polyubiquitination | 2.44e-22 | 3.53e-18 | 6.456 | 12 | 20 | 116 |
| GO:0000082 | G1/S transition of mitotic cell cycle | 5.58e-21 | 8.04e-17 | 6.094 | 12 | 32 | 149 |
| GO:0042981 | regulation of apoptotic process | 6.06e-21 | 8.74e-17 | 6.085 | 12 | 24 | 150 |
| GO:0016071 | mRNA metabolic process | 8.02e-19 | 1.16e-14 | 5.513 | 12 | 31 | 223 |
| GO:0016070 | RNA metabolic process | 2.80e-18 | 4.03e-14 | 5.365 | 12 | 32 | 247 |
| GO:0016032 | viral process | 4.43e-16 | 6.38e-12 | 4.368 | 13 | 55 | 534 |
| GO:0000278 | mitotic cell cycle | 7.30e-16 | 1.05e-11 | 4.703 | 12 | 48 | 391 |
| GO:0005838 | proteasome regulatory particle | 9.12e-16 | 1.32e-11 | 8.729 | 6 | 7 | 12 |
| GO:0043066 | negative regulation of apoptotic process | 1.94e-15 | 2.79e-11 | 4.586 | 12 | 31 | 424 |
| GO:0010467 | gene expression | 8.24e-15 | 1.19e-10 | 4.043 | 13 | 59 | 669 |
| GO:0022624 | proteasome accessory complex | 1.22e-14 | 1.76e-10 | 8.226 | 6 | 8 | 17 |
| GO:0006915 | apoptotic process | 4.87e-14 | 7.02e-10 | 4.197 | 12 | 33 | 555 |
| GO:0005654 | nucleoplasm | 9.07e-14 | 1.31e-09 | 3.456 | 14 | 76 | 1082 |
| GO:0044281 | small molecule metabolic process | 4.31e-13 | 6.22e-09 | 3.294 | 14 | 58 | 1211 |
| GO:0005839 | proteasome core complex | 1.01e-11 | 1.46e-07 | 7.881 | 5 | 8 | 18 |
| GO:0004298 | threonine-type endopeptidase activity | 1.37e-11 | 1.98e-07 | 7.803 | 5 | 8 | 19 |
| GO:0005829 | cytosol | 3.45e-10 | 4.98e-06 | 2.350 | 15 | 132 | 2496 |
| GO:0070062 | extracellular vesicular exosome | 8.91e-08 | 1.29e-03 | 2.200 | 13 | 104 | 2400 |
| GO:0019773 | proteasome core complex, alpha-subunit complex | 3.65e-05 | 5.26e-01 | 7.729 | 2 | 4 | 8 |
| GO:0016020 | membrane | 3.93e-05 | 5.67e-01 | 2.183 | 9 | 90 | 1681 |
| GO:0030234 | enzyme regulator activity | 1.01e-04 | 1.00e+00 | 7.028 | 2 | 3 | 13 |
| GO:0042176 | regulation of protein catabolic process | 1.55e-04 | 1.00e+00 | 6.729 | 2 | 3 | 16 |
| GO:0005844 | polysome | 3.26e-04 | 1.00e+00 | 6.205 | 2 | 4 | 23 |
| GO:0006099 | tricarboxylic acid cycle | 4.85e-04 | 1.00e+00 | 5.921 | 2 | 4 | 28 |
| GO:0005634 | nucleus | 1.10e-03 | 1.00e+00 | 1.159 | 12 | 136 | 4559 |
| GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity | 1.18e-03 | 1.00e+00 | 9.729 | 1 | 1 | 1 |
| GO:0006091 | generation of precursor metabolites and energy | 1.55e-03 | 1.00e+00 | 5.085 | 2 | 3 | 50 |
| GO:0061034 | olfactory bulb mitral cell layer development | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
| GO:0045252 | oxoglutarate dehydrogenase complex | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 2 | 2 |
| GO:0051538 | 3 iron, 4 sulfur cluster binding | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
| GO:0003994 | aconitate hydratase activity | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
| GO:0007127 | meiosis I | 2.36e-03 | 1.00e+00 | 8.729 | 1 | 1 | 2 |
| GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | 3.53e-03 | 1.00e+00 | 8.144 | 1 | 1 | 3 |
| GO:0022028 | tangential migration from the subventricular zone to the olfactory bulb | 3.53e-03 | 1.00e+00 | 8.144 | 1 | 1 | 3 |
| GO:0006104 | succinyl-CoA metabolic process | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 1 | 4 |
| GO:0031467 | Cul7-RING ubiquitin ligase complex | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 1 | 4 |
| GO:0019788 | NEDD8 ligase activity | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 1 | 4 |
| GO:0006734 | NADH metabolic process | 4.71e-03 | 1.00e+00 | 7.729 | 1 | 1 | 4 |
| GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 3 | 5 |
| GO:0031461 | cullin-RING ubiquitin ligase complex | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 1 | 5 |
| GO:0043248 | proteasome assembly | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 1 | 5 |
| GO:0006102 | isocitrate metabolic process | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 1 | 5 |
| GO:0030891 | VCB complex | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 2 | 5 |
| GO:0030976 | thiamine pyrophosphate binding | 5.88e-03 | 1.00e+00 | 7.407 | 1 | 1 | 5 |
| GO:0021695 | cerebellar cortex development | 7.05e-03 | 1.00e+00 | 7.144 | 1 | 2 | 6 |
| GO:0030957 | Tat protein binding | 7.05e-03 | 1.00e+00 | 7.144 | 1 | 3 | 6 |
| GO:0002862 | negative regulation of inflammatory response to antigenic stimulus | 7.05e-03 | 1.00e+00 | 7.144 | 1 | 1 | 6 |
| GO:0006101 | citrate metabolic process | 7.05e-03 | 1.00e+00 | 7.144 | 1 | 1 | 6 |
| GO:0021860 | pyramidal neuron development | 7.05e-03 | 1.00e+00 | 7.144 | 1 | 1 | 6 |
| GO:0031466 | Cul5-RING ubiquitin ligase complex | 7.05e-03 | 1.00e+00 | 7.144 | 1 | 1 | 6 |
| GO:0030529 | ribonucleoprotein complex | 7.53e-03 | 1.00e+00 | 3.921 | 2 | 8 | 112 |
| GO:0044237 | cellular metabolic process | 8.19e-03 | 1.00e+00 | 3.858 | 2 | 5 | 117 |
| GO:0031462 | Cul2-RING ubiquitin ligase complex | 8.22e-03 | 1.00e+00 | 6.921 | 1 | 2 | 7 |
| GO:0005730 | nucleolus | 8.77e-03 | 1.00e+00 | 1.633 | 6 | 69 | 1641 |
| GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 2 | 8 |
| GO:0070688 | MLL5-L complex | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 1 | 8 |
| GO:0006554 | lysine catabolic process | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 2 | 8 |
| GO:0045116 | protein neddylation | 9.39e-03 | 1.00e+00 | 6.729 | 1 | 2 | 8 |
| GO:0008494 | translation activator activity | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 1 | 9 |
| GO:0016887 | ATPase activity | 1.16e-02 | 1.00e+00 | 3.599 | 2 | 7 | 140 |
| GO:0021756 | striatum development | 1.17e-02 | 1.00e+00 | 6.407 | 1 | 1 | 10 |
| GO:0021794 | thalamus development | 1.29e-02 | 1.00e+00 | 6.269 | 1 | 1 | 11 |
| GO:0001530 | lipopolysaccharide binding | 1.52e-02 | 1.00e+00 | 6.028 | 1 | 3 | 13 |
| GO:0035267 | NuA4 histone acetyltransferase complex | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 4 | 14 |
| GO:0050998 | nitric-oxide synthase binding | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 1 | 16 |
| GO:0006103 | 2-oxoglutarate metabolic process | 1.87e-02 | 1.00e+00 | 5.729 | 1 | 1 | 16 |
| GO:0010243 | response to organonitrogen compound | 1.99e-02 | 1.00e+00 | 5.641 | 1 | 3 | 17 |
| GO:0017025 | TBP-class protein binding | 1.99e-02 | 1.00e+00 | 5.641 | 1 | 3 | 17 |
| GO:0003746 | translation elongation factor activity | 1.99e-02 | 1.00e+00 | 5.641 | 1 | 3 | 17 |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 2.22e-02 | 1.00e+00 | 5.481 | 1 | 1 | 19 |
| GO:0048863 | stem cell differentiation | 2.22e-02 | 1.00e+00 | 5.481 | 1 | 1 | 19 |
| GO:0030863 | cortical cytoskeleton | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 1 | 22 |
| GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.56e-02 | 1.00e+00 | 5.269 | 1 | 4 | 22 |
| GO:0043044 | ATP-dependent chromatin remodeling | 2.68e-02 | 1.00e+00 | 5.205 | 1 | 4 | 23 |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.68e-02 | 1.00e+00 | 5.205 | 1 | 3 | 23 |
| GO:0006513 | protein monoubiquitination | 2.68e-02 | 1.00e+00 | 5.205 | 1 | 1 | 23 |
| GO:0005759 | mitochondrial matrix | 2.89e-02 | 1.00e+00 | 2.896 | 2 | 14 | 228 |
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 3 | 26 |
| GO:0031492 | nucleosomal DNA binding | 3.14e-02 | 1.00e+00 | 4.974 | 1 | 4 | 27 |
| GO:0019894 | kinesin binding | 3.25e-02 | 1.00e+00 | 4.921 | 1 | 1 | 28 |
| GO:0019005 | SCF ubiquitin ligase complex | 3.37e-02 | 1.00e+00 | 4.871 | 1 | 1 | 29 |
| GO:0031072 | heat shock protein binding | 3.82e-02 | 1.00e+00 | 4.684 | 1 | 1 | 33 |
| GO:0001895 | retina homeostasis | 3.93e-02 | 1.00e+00 | 4.641 | 1 | 1 | 34 |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | 4.05e-02 | 1.00e+00 | 4.599 | 1 | 3 | 35 |
| GO:0034332 | adherens junction organization | 4.16e-02 | 1.00e+00 | 4.559 | 1 | 1 | 36 |
| GO:0051084 | 'de novo' posttranslational protein folding | 4.28e-02 | 1.00e+00 | 4.519 | 1 | 4 | 37 |
| GO:0021766 | hippocampus development | 4.39e-02 | 1.00e+00 | 4.481 | 1 | 4 | 38 |
| GO:0006096 | glycolytic process | 4.39e-02 | 1.00e+00 | 4.481 | 1 | 4 | 38 |
| GO:0070527 | platelet aggregation | 4.39e-02 | 1.00e+00 | 4.481 | 1 | 2 | 38 |
| GO:0006200 | ATP catabolic process | 4.55e-02 | 1.00e+00 | 2.539 | 2 | 15 | 292 |
| GO:0014070 | response to organic cyclic compound | 4.95e-02 | 1.00e+00 | 4.302 | 1 | 4 | 43 |
| GO:0021762 | substantia nigra development | 5.06e-02 | 1.00e+00 | 4.269 | 1 | 2 | 44 |
| GO:0045727 | positive regulation of translation | 5.06e-02 | 1.00e+00 | 4.269 | 1 | 3 | 44 |
| GO:0019901 | protein kinase binding | 5.27e-02 | 1.00e+00 | 2.420 | 2 | 21 | 317 |
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 6.07e-02 | 1.00e+00 | 4.001 | 1 | 5 | 53 |
| GO:0002244 | hematopoietic progenitor cell differentiation | 6.18e-02 | 1.00e+00 | 3.974 | 1 | 1 | 54 |
| GO:0045216 | cell-cell junction organization | 6.18e-02 | 1.00e+00 | 3.974 | 1 | 2 | 54 |
| GO:0000932 | cytoplasmic mRNA processing body | 6.18e-02 | 1.00e+00 | 3.974 | 1 | 3 | 54 |
| GO:0031966 | mitochondrial membrane | 6.29e-02 | 1.00e+00 | 3.947 | 1 | 1 | 55 |
| GO:0051087 | chaperone binding | 6.73e-02 | 1.00e+00 | 3.846 | 1 | 6 | 59 |
| GO:0034329 | cell junction assembly | 7.72e-02 | 1.00e+00 | 3.641 | 1 | 1 | 68 |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 8.38e-02 | 1.00e+00 | 3.519 | 1 | 6 | 74 |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 8.49e-02 | 1.00e+00 | 3.500 | 1 | 2 | 75 |
| GO:0006928 | cellular component movement | 1.02e-01 | 1.00e+00 | 3.221 | 1 | 7 | 91 |
| GO:0005200 | structural constituent of cytoskeleton | 1.02e-01 | 1.00e+00 | 3.221 | 1 | 8 | 91 |
| GO:0071456 | cellular response to hypoxia | 1.03e-01 | 1.00e+00 | 3.205 | 1 | 6 | 92 |
| GO:0006414 | translational elongation | 1.04e-01 | 1.00e+00 | 3.189 | 1 | 13 | 93 |
| GO:0044267 | cellular protein metabolic process | 1.06e-01 | 1.00e+00 | 1.840 | 2 | 29 | 474 |
| GO:0014069 | postsynaptic density | 1.17e-01 | 1.00e+00 | 3.014 | 1 | 3 | 105 |
| GO:0005506 | iron ion binding | 1.17e-01 | 1.00e+00 | 3.014 | 1 | 4 | 105 |
| GO:0005515 | protein binding | 1.19e-01 | 1.00e+00 | 0.494 | 10 | 184 | 6024 |
| GO:0015630 | microtubule cytoskeleton | 1.22e-01 | 1.00e+00 | 2.947 | 1 | 4 | 110 |
| GO:0072562 | blood microparticle | 1.23e-01 | 1.00e+00 | 2.934 | 1 | 3 | 111 |
| GO:0006325 | chromatin organization | 1.30e-01 | 1.00e+00 | 2.846 | 1 | 5 | 118 |
| GO:0007219 | Notch signaling pathway | 1.32e-01 | 1.00e+00 | 2.822 | 1 | 5 | 120 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 1.39e-01 | 1.00e+00 | 2.751 | 1 | 5 | 126 |
| GO:0009615 | response to virus | 1.39e-01 | 1.00e+00 | 2.751 | 1 | 5 | 126 |
| GO:0000790 | nuclear chromatin | 1.42e-01 | 1.00e+00 | 2.717 | 1 | 9 | 129 |
| GO:0006457 | protein folding | 1.56e-01 | 1.00e+00 | 2.569 | 1 | 7 | 143 |
| GO:0061024 | membrane organization | 1.58e-01 | 1.00e+00 | 2.549 | 1 | 7 | 145 |
| GO:0010628 | positive regulation of gene expression | 1.59e-01 | 1.00e+00 | 2.539 | 1 | 5 | 146 |
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.78e-01 | 1.00e+00 | 2.362 | 1 | 7 | 165 |
| GO:0030424 | axon | 1.79e-01 | 1.00e+00 | 2.354 | 1 | 4 | 166 |
| GO:0031625 | ubiquitin protein ligase binding | 1.90e-01 | 1.00e+00 | 2.253 | 1 | 14 | 178 |
| GO:0032403 | protein complex binding | 1.95e-01 | 1.00e+00 | 2.213 | 1 | 10 | 183 |
| GO:0003924 | GTPase activity | 2.09e-01 | 1.00e+00 | 2.107 | 1 | 12 | 197 |
| GO:0006184 | GTP catabolic process | 2.25e-01 | 1.00e+00 | 1.987 | 1 | 12 | 214 |
| GO:0006412 | translation | 2.39e-01 | 1.00e+00 | 1.883 | 1 | 20 | 230 |
| GO:0004842 | ubiquitin-protein transferase activity | 2.62e-01 | 1.00e+00 | 1.734 | 1 | 6 | 255 |
| GO:0006281 | DNA repair | 2.67e-01 | 1.00e+00 | 1.701 | 1 | 18 | 261 |
| GO:0005856 | cytoskeleton | 2.93e-01 | 1.00e+00 | 1.544 | 1 | 12 | 291 |
| GO:0043234 | protein complex | 2.96e-01 | 1.00e+00 | 1.524 | 1 | 18 | 295 |
| GO:0016567 | protein ubiquitination | 2.96e-01 | 1.00e+00 | 1.524 | 1 | 5 | 295 |
| GO:0005525 | GTP binding | 3.09e-01 | 1.00e+00 | 1.452 | 1 | 12 | 310 |
| GO:0007411 | axon guidance | 3.16e-01 | 1.00e+00 | 1.411 | 1 | 13 | 319 |
| GO:0005813 | centrosome | 3.22e-01 | 1.00e+00 | 1.380 | 1 | 14 | 326 |
| GO:0005739 | mitochondrion | 3.31e-01 | 1.00e+00 | 0.766 | 2 | 28 | 998 |
| GO:0003723 | RNA binding | 3.35e-01 | 1.00e+00 | 1.311 | 1 | 20 | 342 |
| GO:0005925 | focal adhesion | 3.54e-01 | 1.00e+00 | 1.213 | 1 | 19 | 366 |
| GO:0044822 | poly(A) RNA binding | 3.57e-01 | 1.00e+00 | 0.684 | 2 | 49 | 1056 |
| GO:0006508 | proteolysis | 3.63e-01 | 1.00e+00 | 1.166 | 1 | 9 | 378 |
| GO:0007596 | blood coagulation | 4.20e-01 | 1.00e+00 | 0.899 | 1 | 18 | 455 |
| GO:0005524 | ATP binding | 4.60e-01 | 1.00e+00 | 0.387 | 2 | 60 | 1298 |
| GO:0042803 | protein homodimerization activity | 5.12e-01 | 1.00e+00 | 0.512 | 1 | 12 | 595 |
| GO:0045087 | innate immune response | 5.12e-01 | 1.00e+00 | 0.509 | 1 | 24 | 596 |
| GO:0005615 | extracellular space | 6.89e-01 | 1.00e+00 | -0.174 | 1 | 17 | 957 |
| GO:0008270 | zinc ion binding | 7.04e-01 | 1.00e+00 | -0.233 | 1 | 12 | 997 |
| GO:0046872 | metal ion binding | 8.01e-01 | 1.00e+00 | -0.623 | 1 | 25 | 1307 |
| GO:0005737 | cytoplasm | 8.60e-01 | 1.00e+00 | -0.566 | 3 | 110 | 3767 |