int-snw-5709

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.106	7.46e-23	3.22e-05	1.36e-03

wolf-screen-ratio-mammosphere-adherent-int-snw-5709 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
PSMA2	5683	60	1.093	1.106	89	Yes	-
[ PSMD3 ]	5709	57	0.986	1.106	146	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow

Related GO terms (89)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	3.90e-07	5.63e-03	7.435	3	17	50
GO:0000502	proteasome complex	6.14e-07	8.85e-03	7.221	3	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	8.28e-07	1.19e-02	7.079	3	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	8.68e-07	1.25e-02	7.057	3	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.09e-06	1.57e-02	6.950	3	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.18e-06	1.71e-02	6.909	3	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.29e-06	1.86e-02	6.870	3	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.34e-06	1.93e-02	6.850	3	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.57e-06	2.26e-02	6.775	3	23	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2.49e-06	3.59e-02	6.556	3	21	92
GO:0000209	protein polyubiquitination	5.01e-06	7.23e-02	6.221	3	20	116
GO:0005838	proteasome regulatory particle	6.34e-06	9.14e-02	8.909	2	7	12
GO:0000082	G1/S transition of mitotic cell cycle	1.06e-05	1.54e-01	5.860	3	32	149
GO:0042981	regulation of apoptotic process	1.09e-05	1.57e-01	5.850	3	24	150
GO:0022624	proteasome accessory complex	1.30e-05	1.88e-01	8.407	2	8	17
GO:0034641	cellular nitrogen compound metabolic process	1.61e-05	2.32e-01	5.661	3	20	171
GO:0016071	mRNA metabolic process	3.56e-05	5.14e-01	5.278	3	31	223
GO:0016070	RNA metabolic process	4.84e-05	6.98e-01	5.131	3	32	247
GO:0070062	extracellular vesicular exosome	1.27e-04	1.00e+00	2.587	5	104	2400
GO:0005654	nucleoplasm	1.48e-04	1.00e+00	3.415	4	76	1082
GO:0005829	cytosol	1.55e-04	1.00e+00	2.531	5	132	2496
GO:0000278	mitotic cell cycle	1.90e-04	1.00e+00	4.468	3	48	391
GO:0044281	small molecule metabolic process	2.31e-04	1.00e+00	3.252	4	58	1211
GO:0043066	negative regulation of apoptotic process	2.41e-04	1.00e+00	4.351	3	31	424
GO:0019521	D-gluconate metabolic process	3.47e-04	1.00e+00	11.494	1	1	1
GO:0016032	viral process	4.77e-04	1.00e+00	4.018	3	55	534
GO:0006915	apoptotic process	5.35e-04	1.00e+00	3.963	3	33	555
GO:0019322	pentose biosynthetic process	6.93e-04	1.00e+00	10.494	1	2	2
GO:0010467	gene expression	9.26e-04	1.00e+00	3.693	3	59	669
GO:0009051	pentose-phosphate shunt, oxidative branch	1.04e-03	1.00e+00	9.909	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.04e-03	1.00e+00	9.909	1	1	3
GO:0043248	proteasome assembly	1.73e-03	1.00e+00	9.172	1	1	5
GO:0030957	Tat protein binding	2.08e-03	1.00e+00	8.909	1	3	6
GO:0019773	proteasome core complex, alpha-subunit complex	2.77e-03	1.00e+00	8.494	1	4	8
GO:0070688	MLL5-L complex	2.77e-03	1.00e+00	8.494	1	1	8
GO:0006098	pentose-phosphate shunt	3.46e-03	1.00e+00	8.172	1	4	10
GO:0030234	enzyme regulator activity	4.50e-03	1.00e+00	7.794	1	3	13
GO:0035267	NuA4 histone acetyltransferase complex	4.84e-03	1.00e+00	7.687	1	4	14
GO:0050998	nitric-oxide synthase binding	5.54e-03	1.00e+00	7.494	1	1	16
GO:0042176	regulation of protein catabolic process	5.54e-03	1.00e+00	7.494	1	3	16
GO:0005839	proteasome core complex	6.23e-03	1.00e+00	7.324	1	8	18
GO:0004298	threonine-type endopeptidase activity	6.57e-03	1.00e+00	7.246	1	8	19
GO:0048863	stem cell differentiation	6.57e-03	1.00e+00	7.246	1	1	19
GO:0030863	cortical cytoskeleton	7.60e-03	1.00e+00	7.035	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	7.60e-03	1.00e+00	7.035	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	7.95e-03	1.00e+00	6.971	1	4	23
GO:0031492	nucleosomal DNA binding	9.33e-03	1.00e+00	6.739	1	4	27
GO:0050661	NADP binding	9.33e-03	1.00e+00	6.739	1	2	27
GO:0019894	kinesin binding	9.67e-03	1.00e+00	6.687	1	1	28
GO:0001895	retina homeostasis	1.17e-02	1.00e+00	6.407	1	1	34
GO:0034332	adherens junction organization	1.24e-02	1.00e+00	6.324	1	1	36
GO:0051084	'de novo' posttranslational protein folding	1.28e-02	1.00e+00	6.285	1	4	37
GO:0070527	platelet aggregation	1.31e-02	1.00e+00	6.246	1	2	38
GO:0016020	membrane	1.32e-02	1.00e+00	2.364	3	90	1681
GO:0021762	substantia nigra development	1.52e-02	1.00e+00	6.035	1	2	44
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.82e-02	1.00e+00	5.766	1	5	53
GO:0045216	cell-cell junction organization	1.86e-02	1.00e+00	5.739	1	2	54
GO:0000932	cytoplasmic mRNA processing body	1.86e-02	1.00e+00	5.739	1	3	54
GO:0034329	cell junction assembly	2.34e-02	1.00e+00	5.407	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	2.54e-02	1.00e+00	5.285	1	6	74
GO:0005200	structural constituent of cytoskeleton	3.12e-02	1.00e+00	4.986	1	8	91
GO:0006928	cellular component movement	3.12e-02	1.00e+00	4.986	1	7	91
GO:0014069	postsynaptic density	3.59e-02	1.00e+00	4.780	1	3	105
GO:0005634	nucleus	3.73e-02	1.00e+00	1.340	4	136	4559
GO:0072562	blood microparticle	3.79e-02	1.00e+00	4.700	1	3	111
GO:0030529	ribonucleoprotein complex	3.82e-02	1.00e+00	4.687	1	8	112
GO:0006325	chromatin organization	4.02e-02	1.00e+00	4.612	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	4.29e-02	1.00e+00	4.517	1	5	126
GO:0009615	response to virus	4.29e-02	1.00e+00	4.517	1	5	126
GO:0000790	nuclear chromatin	4.39e-02	1.00e+00	4.483	1	9	129
GO:0006457	protein folding	4.86e-02	1.00e+00	4.334	1	7	143
GO:0061024	membrane organization	4.93e-02	1.00e+00	4.314	1	7	145
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5.59e-02	1.00e+00	4.128	1	7	165
GO:0030424	axon	5.62e-02	1.00e+00	4.119	1	4	166
GO:0005975	carbohydrate metabolic process	8.47e-02	1.00e+00	3.511	1	9	253
GO:0005856	cytoskeleton	9.69e-02	1.00e+00	3.309	1	12	291
GO:0043234	protein complex	9.82e-02	1.00e+00	3.290	1	18	295
GO:0019901	protein kinase binding	1.05e-01	1.00e+00	3.186	1	21	317
GO:0007411	axon guidance	1.06e-01	1.00e+00	3.177	1	13	319
GO:0005925	focal adhesion	1.21e-01	1.00e+00	2.978	1	19	366
GO:0055114	oxidation-reduction process	1.37e-01	1.00e+00	2.780	1	12	420
GO:0007596	blood coagulation	1.48e-01	1.00e+00	2.664	1	18	455
GO:0044267	cellular protein metabolic process	1.54e-01	1.00e+00	2.605	1	29	474
GO:0045087	innate immune response	1.90e-01	1.00e+00	2.275	1	24	596
GO:0005615	extracellular space	2.91e-01	1.00e+00	1.592	1	17	957
GO:0005515	protein binding	3.48e-01	1.00e+00	0.523	3	184	6024
GO:0005524	ATP binding	3.76e-01	1.00e+00	1.152	1	60	1298
GO:0005737	cytoplasm	3.91e-01	1.00e+00	0.615	2	110	3767
GO:0005730	nucleolus	4.53e-01	1.00e+00	0.814	1	69	1641

Wolf-ratios-Mammosphere-Adherent

int-snw-5709

Statistics

Genes (5)

Interactions (7)

Related GO terms (89)