int-snw-4598

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.950	4.25e-16	1.78e-03	3.15e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-4598 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACO2	50	50	1.000	1.076	191	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
[ MVK ]	4598	1	-0.344	0.950	38	-	Yes
POLR2L	5441	1	0.529	0.950	63	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
MVK	4598	POLR2L	5441	pp	--	int.I2D: YeastMedium
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
ACO2	50	MVK	4598	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	MVK	4598	pp	--	int.I2D: YeastMedium
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
RPSA	3921	POLR2L	5441	pp	--	int.I2D: YeastMedium
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow

Related GO terms (146)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005829	cytosol	1.59e-04	1.00e+00	2.308	6	132	2496
GO:0004496	mevalonate kinase activity	4.85e-04	1.00e+00	11.009	1	1	1
GO:0019521	D-gluconate metabolic process	4.85e-04	1.00e+00	11.009	1	1	1
GO:0051538	3 iron, 4 sulfur cluster binding	9.70e-04	1.00e+00	10.009	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.70e-04	1.00e+00	10.009	1	1	2
GO:0019322	pentose biosynthetic process	9.70e-04	1.00e+00	10.009	1	2	2
GO:0003994	aconitate hydratase activity	9.70e-04	1.00e+00	10.009	1	1	2
GO:0005055	laminin receptor activity	9.70e-04	1.00e+00	10.009	1	1	2
GO:0006407	rRNA export from nucleus	9.70e-04	1.00e+00	10.009	1	1	2
GO:0044281	small molecule metabolic process	1.41e-03	1.00e+00	2.767	4	58	1211
GO:0009051	pentose-phosphate shunt, oxidative branch	1.46e-03	1.00e+00	9.424	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.46e-03	1.00e+00	9.424	1	1	3
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	1.46e-03	1.00e+00	9.424	1	1	3
GO:0016032	viral process	1.58e-03	1.00e+00	3.533	3	55	534
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.94e-03	1.00e+00	9.009	1	1	4
GO:0030686	90S preribosome	1.94e-03	1.00e+00	9.009	1	1	4
GO:0070062	extracellular vesicular exosome	1.98e-03	1.00e+00	2.102	5	104	2400
GO:0043248	proteasome assembly	2.42e-03	1.00e+00	8.687	1	1	5
GO:0006102	isocitrate metabolic process	2.42e-03	1.00e+00	8.687	1	1	5
GO:0030957	Tat protein binding	2.91e-03	1.00e+00	8.424	1	3	6
GO:0006101	citrate metabolic process	2.91e-03	1.00e+00	8.424	1	1	6
GO:0006356	regulation of transcription from RNA polymerase I promoter	2.91e-03	1.00e+00	8.424	1	2	6
GO:0010467	gene expression	3.02e-03	1.00e+00	3.208	3	59	669
GO:0000028	ribosomal small subunit assembly	3.39e-03	1.00e+00	8.201	1	1	7
GO:0001055	RNA polymerase II activity	3.88e-03	1.00e+00	8.009	1	3	8
GO:0070688	MLL5-L complex	3.88e-03	1.00e+00	8.009	1	1	8
GO:0016071	mRNA metabolic process	4.75e-03	1.00e+00	4.208	2	31	223
GO:0006098	pentose-phosphate shunt	4.84e-03	1.00e+00	7.687	1	4	10
GO:0008299	isoprenoid biosynthetic process	5.33e-03	1.00e+00	7.549	1	1	11
GO:0001054	RNA polymerase I activity	5.33e-03	1.00e+00	7.549	1	3	11
GO:0016070	RNA metabolic process	5.80e-03	1.00e+00	4.060	2	32	247
GO:0005736	DNA-directed RNA polymerase I complex	5.81e-03	1.00e+00	7.424	1	3	12
GO:0005838	proteasome regulatory particle	5.81e-03	1.00e+00	7.424	1	7	12
GO:0035267	NuA4 histone acetyltransferase complex	6.78e-03	1.00e+00	7.201	1	4	14
GO:0050998	nitric-oxide synthase binding	7.74e-03	1.00e+00	7.009	1	1	16
GO:0005665	DNA-directed RNA polymerase II, core complex	7.74e-03	1.00e+00	7.009	1	4	16
GO:0001056	RNA polymerase III activity	7.74e-03	1.00e+00	7.009	1	3	16
GO:0005666	DNA-directed RNA polymerase III complex	8.22e-03	1.00e+00	6.921	1	3	17
GO:0022624	proteasome accessory complex	8.22e-03	1.00e+00	6.921	1	8	17
GO:0006386	termination of RNA polymerase III transcription	8.71e-03	1.00e+00	6.839	1	3	18
GO:0006385	transcription elongation from RNA polymerase III promoter	8.71e-03	1.00e+00	6.839	1	3	18
GO:0048863	stem cell differentiation	9.19e-03	1.00e+00	6.761	1	1	19
GO:0030863	cortical cytoskeleton	1.06e-02	1.00e+00	6.549	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.06e-02	1.00e+00	6.549	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.11e-02	1.00e+00	6.485	1	4	23
GO:0043236	laminin binding	1.11e-02	1.00e+00	6.485	1	1	23
GO:0005654	nucleoplasm	1.17e-02	1.00e+00	2.514	3	76	1082
GO:0003899	DNA-directed RNA polymerase activity	1.21e-02	1.00e+00	6.365	1	3	25
GO:0043022	ribosome binding	1.30e-02	1.00e+00	6.254	1	3	27
GO:0050661	NADP binding	1.30e-02	1.00e+00	6.254	1	2	27
GO:0031492	nucleosomal DNA binding	1.30e-02	1.00e+00	6.254	1	4	27
GO:0006099	tricarboxylic acid cycle	1.35e-02	1.00e+00	6.201	1	4	28
GO:0019894	kinesin binding	1.35e-02	1.00e+00	6.201	1	1	28
GO:0006360	transcription from RNA polymerase I promoter	1.45e-02	1.00e+00	6.102	1	5	30
GO:0006370	7-methylguanosine mRNA capping	1.45e-02	1.00e+00	6.102	1	5	30
GO:0001895	retina homeostasis	1.64e-02	1.00e+00	5.921	1	1	34
GO:0006695	cholesterol biosynthetic process	1.64e-02	1.00e+00	5.921	1	4	34
GO:0051539	4 iron, 4 sulfur cluster binding	1.69e-02	1.00e+00	5.879	1	3	35
GO:0034332	adherens junction organization	1.73e-02	1.00e+00	5.839	1	1	36
GO:0051084	'de novo' posttranslational protein folding	1.78e-02	1.00e+00	5.799	1	4	37
GO:0070527	platelet aggregation	1.83e-02	1.00e+00	5.761	1	2	38
GO:0022627	cytosolic small ribosomal subunit	1.88e-02	1.00e+00	5.723	1	4	39
GO:0006383	transcription from RNA polymerase III promoter	1.88e-02	1.00e+00	5.723	1	3	39
GO:0044267	cellular protein metabolic process	2.03e-02	1.00e+00	3.120	2	29	474
GO:0021762	substantia nigra development	2.12e-02	1.00e+00	5.549	1	2	44
GO:0050434	positive regulation of viral transcription	2.12e-02	1.00e+00	5.549	1	6	44
GO:0006283	transcription-coupled nucleotide-excision repair	2.21e-02	1.00e+00	5.485	1	7	46
GO:0006091	generation of precursor metabolites and energy	2.40e-02	1.00e+00	5.365	1	3	50
GO:0006521	regulation of cellular amino acid metabolic process	2.40e-02	1.00e+00	5.365	1	17	50
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.54e-02	1.00e+00	5.281	1	5	53
GO:0045216	cell-cell junction organization	2.59e-02	1.00e+00	5.254	1	2	54
GO:0050728	negative regulation of inflammatory response	2.69e-02	1.00e+00	5.201	1	1	56
GO:0000502	proteasome complex	2.78e-02	1.00e+00	5.151	1	17	58
GO:0032481	positive regulation of type I interferon production	2.92e-02	1.00e+00	5.078	1	6	61
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.07e-02	1.00e+00	5.009	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.11e-02	1.00e+00	4.986	1	22	65
GO:0045087	innate immune response	3.12e-02	1.00e+00	2.790	2	24	596
GO:0006368	transcription elongation from RNA polymerase II promoter	3.21e-02	1.00e+00	4.943	1	6	67
GO:0006289	nucleotide-excision repair	3.25e-02	1.00e+00	4.921	1	11	68
GO:0034329	cell junction assembly	3.25e-02	1.00e+00	4.921	1	1	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.35e-02	1.00e+00	4.879	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.44e-02	1.00e+00	4.839	1	20	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.54e-02	1.00e+00	4.799	1	6	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.54e-02	1.00e+00	4.799	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	3.58e-02	1.00e+00	4.780	1	20	75
GO:0005634	nucleus	3.60e-02	1.00e+00	1.176	5	136	4559
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.77e-02	1.00e+00	4.705	1	23	79
GO:0016020	membrane	3.85e-02	1.00e+00	1.879	3	90	1681
GO:0019083	viral transcription	3.87e-02	1.00e+00	4.669	1	10	81
GO:0005777	peroxisome	4.01e-02	1.00e+00	4.616	1	4	84
GO:0006415	translational termination	4.15e-02	1.00e+00	4.566	1	10	87
GO:0016310	phosphorylation	4.29e-02	1.00e+00	4.517	1	4	90
GO:0006928	cellular component movement	4.33e-02	1.00e+00	4.501	1	7	91
GO:0005200	structural constituent of cytoskeleton	4.33e-02	1.00e+00	4.501	1	8	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.38e-02	1.00e+00	4.485	1	21	92
GO:0006414	translational elongation	4.43e-02	1.00e+00	4.470	1	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.94e-02	1.00e+00	4.308	1	10	104
GO:0014069	postsynaptic density	4.99e-02	1.00e+00	4.294	1	3	105
GO:0005506	iron ion binding	4.99e-02	1.00e+00	4.294	1	4	105
GO:0072562	blood microparticle	5.27e-02	1.00e+00	4.214	1	3	111
GO:0030529	ribonucleoprotein complex	5.31e-02	1.00e+00	4.201	1	8	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.40e-02	1.00e+00	4.176	1	11	114
GO:0019058	viral life cycle	5.45e-02	1.00e+00	4.163	1	13	115
GO:0000209	protein polyubiquitination	5.50e-02	1.00e+00	4.151	1	20	116
GO:0044237	cellular metabolic process	5.54e-02	1.00e+00	4.138	1	5	117
GO:0006325	chromatin organization	5.59e-02	1.00e+00	4.126	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	5.96e-02	1.00e+00	4.031	1	5	126
GO:0000790	nuclear chromatin	6.10e-02	1.00e+00	3.998	1	9	129
GO:0006413	translational initiation	6.19e-02	1.00e+00	3.975	1	17	131
GO:0003735	structural constituent of ribosome	6.46e-02	1.00e+00	3.911	1	10	137
GO:0006457	protein folding	6.74e-02	1.00e+00	3.849	1	7	143
GO:0061024	membrane organization	6.83e-02	1.00e+00	3.829	1	7	145
GO:0000082	G1/S transition of mitotic cell cycle	7.01e-02	1.00e+00	3.790	1	32	149
GO:0042981	regulation of apoptotic process	7.06e-02	1.00e+00	3.780	1	24	150
GO:0000398	mRNA splicing, via spliceosome	7.69e-02	1.00e+00	3.651	1	8	164
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	7.74e-02	1.00e+00	3.642	1	7	165
GO:0030424	axon	7.79e-02	1.00e+00	3.634	1	4	166
GO:0034641	cellular nitrogen compound metabolic process	8.01e-02	1.00e+00	3.591	1	20	171
GO:0006367	transcription initiation from RNA polymerase II promoter	8.60e-02	1.00e+00	3.485	1	8	184
GO:0008380	RNA splicing	1.06e-01	1.00e+00	3.176	1	11	228
GO:0006412	translation	1.06e-01	1.00e+00	3.163	1	20	230
GO:0005759	mitochondrial matrix	1.06e-01	1.00e+00	3.176	1	14	228
GO:0005975	carbohydrate metabolic process	1.17e-01	1.00e+00	3.026	1	9	253
GO:0006281	DNA repair	1.20e-01	1.00e+00	2.981	1	18	261
GO:0005524	ATP binding	1.25e-01	1.00e+00	1.667	2	60	1298
GO:0005856	cytoskeleton	1.33e-01	1.00e+00	2.824	1	12	291
GO:0043234	protein complex	1.35e-01	1.00e+00	2.804	1	18	295
GO:0019901	protein kinase binding	1.44e-01	1.00e+00	2.700	1	21	317
GO:0007411	axon guidance	1.45e-01	1.00e+00	2.691	1	13	319
GO:0005925	focal adhesion	1.65e-01	1.00e+00	2.493	1	19	366
GO:0007155	cell adhesion	1.66e-01	1.00e+00	2.481	1	6	369
GO:0000278	mitotic cell cycle	1.75e-01	1.00e+00	2.398	1	48	391
GO:0055114	oxidation-reduction process	1.87e-01	1.00e+00	2.294	1	12	420
GO:0006366	transcription from RNA polymerase II promoter	1.87e-01	1.00e+00	2.298	1	10	419
GO:0043066	negative regulation of apoptotic process	1.89e-01	1.00e+00	2.281	1	31	424
GO:0007596	blood coagulation	2.01e-01	1.00e+00	2.179	1	18	455
GO:0042802	identical protein binding	2.13e-01	1.00e+00	2.090	1	20	484
GO:0006915	apoptotic process	2.40e-01	1.00e+00	1.892	1	33	555
GO:0005615	extracellular space	3.82e-01	1.00e+00	1.106	1	17	957
GO:0008270	zinc ion binding	3.94e-01	1.00e+00	1.047	1	12	997
GO:0005739	mitochondrion	3.95e-01	1.00e+00	1.046	1	28	998
GO:0044822	poly(A) RNA binding	4.13e-01	1.00e+00	0.964	1	49	1056
GO:0003677	DNA binding	4.61e-01	1.00e+00	0.758	1	28	1218
GO:0005737	cytoplasm	5.83e-01	1.00e+00	0.130	2	110	3767
GO:0005515	protein binding	6.18e-01	1.00e+00	0.037	3	184	6024
GO:0005886	plasma membrane	7.49e-01	1.00e+00	-0.326	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-4598

Statistics

Genes (7)

Interactions (10)

Related GO terms (146)