int-snw-4528

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.983	2.05e-17	8.37e-04	1.80e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-4528 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
NAA10	8260	5	0.668	0.983	136	Yes	-
ACO2	50	50	1.000	1.076	191	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
RSL24D1	51187	36	1.300	1.020	59	Yes	-
[ MTIF2 ]	4528	1	-0.119	0.983	39	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
MTIF2	4528	RSL24D1	51187	pp	--	int.I2D: YeastMedium
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
ACO2	50	PGD	5226	pp	--	int.I2D: YeastLow
ACO2	50	MTIF2	4528	pp	--	int.I2D: BioGrid_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	NAA10	8260	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	NAA10	8260	pp	--	int.I2D: IntAct_Yeast
MTIF2	4528	NAA10	8260	pp	--	int.I2D: BioGrid_Yeast
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow

Related GO terms (132)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0043022	ribosome binding	9.38e-05	1.00e+00	7.061	2	3	27
GO:0019521	D-gluconate metabolic process	5.55e-04	1.00e+00	10.816	1	1	1
GO:0051538	3 iron, 4 sulfur cluster binding	1.11e-03	1.00e+00	9.816	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.11e-03	1.00e+00	9.816	1	1	2
GO:0019322	pentose biosynthetic process	1.11e-03	1.00e+00	9.816	1	2	2
GO:0003994	aconitate hydratase activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0005055	laminin receptor activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006407	rRNA export from nucleus	1.11e-03	1.00e+00	9.816	1	1	2
GO:0009051	pentose-phosphate shunt, oxidative branch	1.66e-03	1.00e+00	9.231	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.66e-03	1.00e+00	9.231	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.22e-03	1.00e+00	8.816	1	1	4
GO:0030686	90S preribosome	2.22e-03	1.00e+00	8.816	1	1	4
GO:0001732	formation of cytoplasmic translation initiation complex	2.22e-03	1.00e+00	8.816	1	1	4
GO:0043248	proteasome assembly	2.77e-03	1.00e+00	8.494	1	1	5
GO:0006323	DNA packaging	2.77e-03	1.00e+00	8.494	1	1	5
GO:0006102	isocitrate metabolic process	2.77e-03	1.00e+00	8.494	1	1	5
GO:0004596	peptide alpha-N-acetyltransferase activity	2.77e-03	1.00e+00	8.494	1	1	5
GO:0031415	NatA complex	2.77e-03	1.00e+00	8.494	1	1	5
GO:0006474	N-terminal protein amino acid acetylation	3.32e-03	1.00e+00	8.231	1	1	6
GO:0030957	Tat protein binding	3.32e-03	1.00e+00	8.231	1	3	6
GO:0006101	citrate metabolic process	3.32e-03	1.00e+00	8.231	1	1	6
GO:0032790	ribosome disassembly	3.88e-03	1.00e+00	8.009	1	1	7
GO:0000028	ribosomal small subunit assembly	3.88e-03	1.00e+00	8.009	1	1	7
GO:0006475	internal protein amino acid acetylation	3.88e-03	1.00e+00	8.009	1	1	7
GO:0008080	N-acetyltransferase activity	4.43e-03	1.00e+00	7.816	1	1	8
GO:0070688	MLL5-L complex	4.43e-03	1.00e+00	7.816	1	1	8
GO:0043024	ribosomal small subunit binding	4.98e-03	1.00e+00	7.646	1	1	9
GO:0006098	pentose-phosphate shunt	5.53e-03	1.00e+00	7.494	1	4	10
GO:0016407	acetyltransferase activity	5.53e-03	1.00e+00	7.494	1	1	10
GO:0016071	mRNA metabolic process	6.27e-03	1.00e+00	4.015	2	31	223
GO:0005838	proteasome regulatory particle	6.64e-03	1.00e+00	7.231	1	7	12
GO:0016070	RNA metabolic process	7.64e-03	1.00e+00	3.868	2	32	247
GO:0035267	NuA4 histone acetyltransferase complex	7.74e-03	1.00e+00	7.009	1	4	14
GO:0016020	membrane	8.74e-03	1.00e+00	2.101	4	90	1681
GO:0050998	nitric-oxide synthase binding	8.84e-03	1.00e+00	6.816	1	1	16
GO:0022624	proteasome accessory complex	9.39e-03	1.00e+00	6.729	1	8	17
GO:0048863	stem cell differentiation	1.05e-02	1.00e+00	6.568	1	1	19
GO:0030863	cortical cytoskeleton	1.21e-02	1.00e+00	6.357	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.357	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.27e-02	1.00e+00	6.293	1	4	23
GO:0043236	laminin binding	1.27e-02	1.00e+00	6.293	1	1	23
GO:0008135	translation factor activity, nucleic acid binding	1.32e-02	1.00e+00	6.231	1	7	24
GO:0050661	NADP binding	1.49e-02	1.00e+00	6.061	1	2	27
GO:0031492	nucleosomal DNA binding	1.49e-02	1.00e+00	6.061	1	4	27
GO:0006099	tricarboxylic acid cycle	1.54e-02	1.00e+00	6.009	1	4	28
GO:0019894	kinesin binding	1.54e-02	1.00e+00	6.009	1	1	28
GO:0042254	ribosome biogenesis	1.65e-02	1.00e+00	5.909	1	1	30
GO:0001895	retina homeostasis	1.87e-02	1.00e+00	5.729	1	1	34
GO:0051539	4 iron, 4 sulfur cluster binding	1.93e-02	1.00e+00	5.687	1	3	35
GO:0034332	adherens junction organization	1.98e-02	1.00e+00	5.646	1	1	36
GO:0006446	regulation of translational initiation	1.98e-02	1.00e+00	5.646	1	4	36
GO:0051084	'de novo' posttranslational protein folding	2.03e-02	1.00e+00	5.607	1	4	37
GO:0070527	platelet aggregation	2.09e-02	1.00e+00	5.568	1	2	38
GO:0022627	cytosolic small ribosomal subunit	2.14e-02	1.00e+00	5.531	1	4	39
GO:0044281	small molecule metabolic process	2.40e-02	1.00e+00	2.159	3	58	1211
GO:0021762	substantia nigra development	2.42e-02	1.00e+00	5.357	1	2	44
GO:0044267	cellular protein metabolic process	2.65e-02	1.00e+00	2.927	2	29	474
GO:0003743	translation initiation factor activity	2.69e-02	1.00e+00	5.201	1	8	49
GO:0006091	generation of precursor metabolites and energy	2.74e-02	1.00e+00	5.172	1	3	50
GO:0006521	regulation of cellular amino acid metabolic process	2.74e-02	1.00e+00	5.172	1	17	50
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.90e-02	1.00e+00	5.088	1	5	53
GO:0045216	cell-cell junction organization	2.96e-02	1.00e+00	5.061	1	2	54
GO:0070062	extracellular vesicular exosome	3.05e-02	1.00e+00	1.587	4	104	2400
GO:0000502	proteasome complex	3.17e-02	1.00e+00	4.958	1	17	58
GO:0016032	viral process	3.30e-02	1.00e+00	2.755	2	55	534
GO:0005829	cytosol	3.48e-02	1.00e+00	1.531	4	132	2496
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.50e-02	1.00e+00	4.816	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.55e-02	1.00e+00	4.794	1	22	65
GO:0034329	cell junction assembly	3.71e-02	1.00e+00	4.729	1	1	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.82e-02	1.00e+00	4.687	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.93e-02	1.00e+00	4.646	1	20	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.03e-02	1.00e+00	4.607	1	6	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.03e-02	1.00e+00	4.607	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.09e-02	1.00e+00	4.587	1	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.30e-02	1.00e+00	4.512	1	23	79
GO:0019083	viral transcription	4.41e-02	1.00e+00	4.476	1	10	81
GO:0006415	translational termination	4.73e-02	1.00e+00	4.373	1	10	87
GO:0006928	cellular component movement	4.94e-02	1.00e+00	4.308	1	7	91
GO:0005200	structural constituent of cytoskeleton	4.94e-02	1.00e+00	4.308	1	8	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.99e-02	1.00e+00	4.293	1	21	92
GO:0010467	gene expression	4.99e-02	1.00e+00	2.430	2	59	669
GO:0006414	translational elongation	5.04e-02	1.00e+00	4.277	1	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.63e-02	1.00e+00	4.116	1	10	104
GO:0014069	postsynaptic density	5.68e-02	1.00e+00	4.102	1	3	105
GO:0005506	iron ion binding	5.68e-02	1.00e+00	4.102	1	4	105
GO:0072562	blood microparticle	5.99e-02	1.00e+00	4.022	1	3	111
GO:0030529	ribonucleoprotein complex	6.05e-02	1.00e+00	4.009	1	8	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.15e-02	1.00e+00	3.983	1	11	114
GO:0019058	viral life cycle	6.20e-02	1.00e+00	3.971	1	13	115
GO:0000209	protein polyubiquitination	6.26e-02	1.00e+00	3.958	1	20	116
GO:0044237	cellular metabolic process	6.31e-02	1.00e+00	3.946	1	5	117
GO:0006325	chromatin organization	6.36e-02	1.00e+00	3.933	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	6.78e-02	1.00e+00	3.839	1	5	126
GO:0000790	nuclear chromatin	6.94e-02	1.00e+00	3.805	1	9	129
GO:0006413	translational initiation	7.04e-02	1.00e+00	3.783	1	17	131
GO:0005634	nucleus	7.14e-02	1.00e+00	0.984	5	136	4559
GO:0003735	structural constituent of ribosome	7.35e-02	1.00e+00	3.718	1	10	137
GO:0006457	protein folding	7.66e-02	1.00e+00	3.656	1	7	143
GO:0061024	membrane organization	7.77e-02	1.00e+00	3.636	1	7	145
GO:0000082	G1/S transition of mitotic cell cycle	7.97e-02	1.00e+00	3.597	1	32	149
GO:0042981	regulation of apoptotic process	8.03e-02	1.00e+00	3.587	1	24	150
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.80e-02	1.00e+00	3.450	1	7	165
GO:0030424	axon	8.85e-02	1.00e+00	3.441	1	4	166
GO:0034641	cellular nitrogen compound metabolic process	9.10e-02	1.00e+00	3.398	1	20	171
GO:0005739	mitochondrion	1.01e-01	1.00e+00	1.853	2	28	998
GO:0003924	GTPase activity	1.04e-01	1.00e+00	3.194	1	12	197
GO:0005622	intracellular	1.09e-01	1.00e+00	3.123	1	6	207
GO:0044822	poly(A) RNA binding	1.12e-01	1.00e+00	1.772	2	49	1056
GO:0006184	GTP catabolic process	1.13e-01	1.00e+00	3.075	1	12	214
GO:0005654	nucleoplasm	1.16e-01	1.00e+00	1.737	2	76	1082
GO:0005759	mitochondrial matrix	1.20e-01	1.00e+00	2.983	1	14	228
GO:0006412	translation	1.21e-01	1.00e+00	2.971	1	20	230
GO:0005975	carbohydrate metabolic process	1.32e-01	1.00e+00	2.833	1	9	253
GO:0005856	cytoskeleton	1.50e-01	1.00e+00	2.631	1	12	291
GO:0043234	protein complex	1.52e-01	1.00e+00	2.612	1	18	295
GO:0005525	GTP binding	1.60e-01	1.00e+00	2.540	1	12	310
GO:0019901	protein kinase binding	1.63e-01	1.00e+00	2.508	1	21	317
GO:0007411	axon guidance	1.64e-01	1.00e+00	2.499	1	13	319
GO:0005925	focal adhesion	1.86e-01	1.00e+00	2.300	1	19	366
GO:0007155	cell adhesion	1.87e-01	1.00e+00	2.289	1	6	369
GO:0000278	mitotic cell cycle	1.97e-01	1.00e+00	2.205	1	48	391
GO:0055114	oxidation-reduction process	2.11e-01	1.00e+00	2.102	1	12	420
GO:0043066	negative regulation of apoptotic process	2.12e-01	1.00e+00	2.088	1	31	424
GO:0007596	blood coagulation	2.26e-01	1.00e+00	1.986	1	18	455
GO:0005730	nucleolus	2.29e-01	1.00e+00	1.136	2	69	1641
GO:0006915	apoptotic process	2.69e-01	1.00e+00	1.700	1	33	555
GO:0045087	innate immune response	2.87e-01	1.00e+00	1.597	1	24	596
GO:0005737	cytoplasm	3.49e-01	1.00e+00	0.522	3	110	3767
GO:0005615	extracellular space	4.23e-01	1.00e+00	0.914	1	17	957
GO:0005515	protein binding	4.47e-01	1.00e+00	0.260	4	184	6024
GO:0005524	ATP binding	5.30e-01	1.00e+00	0.474	1	60	1298
GO:0005886	plasma membrane	7.94e-01	1.00e+00	-0.518	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-4528

Statistics

Genes (8)

Interactions (11)

Related GO terms (132)