int-snw-317781

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.951	3.77e-16	1.73e-03	3.09e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-317781 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	17	0.807	1.007	333	-	-
EEF2	1938	27	0.890	1.043	301	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
ATP6V1B2	526	44	0.881	1.076	278	-	-
[ DDX51 ]	317781	1	0.059	0.951	30	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ATP6V1B2	526	DDX51	317781	pp	--	int.I2D: IntAct_Yeast
RPS11	6205	DDX51	317781	pp	--	int.I2D: IntAct_Yeast
ACTB	60	EEF2	1938	pp	--	int.I2D: YeastLow, IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
CAD	790	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
EEF2	1938	PGD	5226	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2	526	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
ACTB	60	ATP6V1B2	526	pp	--	int.I2D: BioGrid_Yeast
CAD	790	DDX51	317781	pp	--	int.I2D: IntAct_Yeast
EEF2	1938	DDX51	317781	pp	--	int.I2D: IntAct_Yeast
ACTB	60	CAD	790	pp	--	int.I2D: IntAct_Yeast

Related GO terms (153)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006414	translational elongation	1.99e-07	2.87e-03	6.107	4	13	93
GO:0044267	cellular protein metabolic process	4.24e-06	6.12e-02	4.079	5	29	474
GO:0070062	extracellular vesicular exosome	4.47e-06	6.44e-02	2.417	8	104	2400
GO:0005829	cytosol	6.07e-06	8.76e-02	2.361	8	132	2496
GO:0006412	translation	7.46e-06	1.08e-01	4.801	4	20	230
GO:0016020	membrane	8.40e-06	1.21e-01	2.738	7	90	1681
GO:0019083	viral transcription	1.40e-05	2.02e-01	5.891	3	10	81
GO:0006415	translational termination	1.73e-05	2.50e-01	5.788	3	10	87
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.96e-05	4.28e-01	5.531	3	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.90e-05	5.63e-01	5.398	3	11	114
GO:0019058	viral life cycle	4.01e-05	5.78e-01	5.386	3	13	115
GO:0006413	translational initiation	5.91e-05	8.52e-01	5.198	3	17	131
GO:0003735	structural constituent of ribosome	6.75e-05	9.74e-01	5.133	3	10	137
GO:0044822	poly(A) RNA binding	2.05e-04	1.00e+00	2.924	5	49	1056
GO:0022627	cytosolic small ribosomal subunit	2.53e-04	1.00e+00	6.361	2	4	39
GO:0016071	mRNA metabolic process	2.86e-04	1.00e+00	4.430	3	31	223
GO:0016070	RNA metabolic process	3.86e-04	1.00e+00	4.283	3	32	247
GO:0010467	gene expression	4.79e-04	1.00e+00	3.260	4	59	669
GO:0004151	dihydroorotase activity	6.24e-04	1.00e+00	10.646	1	1	1
GO:0019521	D-gluconate metabolic process	6.24e-04	1.00e+00	10.646	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	6.24e-04	1.00e+00	10.646	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	6.24e-04	1.00e+00	10.646	1	1	1
GO:0070335	aspartate binding	6.24e-04	1.00e+00	10.646	1	1	1
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.25e-03	1.00e+00	9.646	1	1	2
GO:0019322	pentose biosynthetic process	1.25e-03	1.00e+00	9.646	1	2	2
GO:0005055	laminin receptor activity	1.25e-03	1.00e+00	9.646	1	1	2
GO:0006407	rRNA export from nucleus	1.25e-03	1.00e+00	9.646	1	1	2
GO:0070409	carbamoyl phosphate biosynthetic process	1.25e-03	1.00e+00	9.646	1	1	2
GO:0006364	rRNA processing	1.47e-03	1.00e+00	5.092	2	6	94
GO:0009051	pentose-phosphate shunt, oxidative branch	1.87e-03	1.00e+00	9.061	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.87e-03	1.00e+00	9.061	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	1.87e-03	1.00e+00	9.061	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	1.87e-03	1.00e+00	9.061	1	1	3
GO:0030529	ribonucleoprotein complex	2.08e-03	1.00e+00	4.839	2	8	112
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.49e-03	1.00e+00	8.646	1	1	4
GO:0030686	90S preribosome	2.49e-03	1.00e+00	8.646	1	1	4
GO:0006543	glutamine catabolic process	2.49e-03	1.00e+00	8.646	1	1	4
GO:0051414	response to cortisol	3.12e-03	1.00e+00	8.324	1	1	5
GO:0016032	viral process	3.59e-03	1.00e+00	3.170	3	55	534
GO:0030957	Tat protein binding	3.74e-03	1.00e+00	8.061	1	3	6
GO:0046134	pyrimidine nucleoside biosynthetic process	3.74e-03	1.00e+00	8.061	1	1	6
GO:0033180	proton-transporting V-type ATPase, V1 domain	4.36e-03	1.00e+00	7.839	1	2	7
GO:0000028	ribosomal small subunit assembly	4.36e-03	1.00e+00	7.839	1	1	7
GO:0070688	MLL5-L complex	4.98e-03	1.00e+00	7.646	1	1	8
GO:0006228	UTP biosynthetic process	5.60e-03	1.00e+00	7.476	1	1	9
GO:0014075	response to amine	5.60e-03	1.00e+00	7.476	1	1	9
GO:0031000	response to caffeine	5.60e-03	1.00e+00	7.476	1	2	9
GO:0008494	translation activator activity	5.60e-03	1.00e+00	7.476	1	1	9
GO:0005524	ATP binding	5.68e-03	1.00e+00	2.304	4	60	1298
GO:0006098	pentose-phosphate shunt	6.22e-03	1.00e+00	7.324	1	4	10
GO:0042273	ribosomal large subunit biogenesis	8.09e-03	1.00e+00	6.946	1	4	13
GO:0035267	NuA4 histone acetyltransferase complex	8.70e-03	1.00e+00	6.839	1	4	14
GO:0046961	proton-transporting ATPase activity, rotational mechanism	9.32e-03	1.00e+00	6.739	1	3	15
GO:0046034	ATP metabolic process	9.32e-03	1.00e+00	6.739	1	1	15
GO:0050998	nitric-oxide synthase binding	9.94e-03	1.00e+00	6.646	1	1	16
GO:0006541	glutamine metabolic process	1.06e-02	1.00e+00	6.559	1	1	17
GO:0003746	translation elongation factor activity	1.06e-02	1.00e+00	6.559	1	3	17
GO:0017144	drug metabolic process	1.12e-02	1.00e+00	6.476	1	1	18
GO:0015078	hydrogen ion transmembrane transporter activity	1.18e-02	1.00e+00	6.398	1	3	19
GO:0071364	cellular response to epidermal growth factor stimulus	1.30e-02	1.00e+00	6.254	1	1	21
GO:0006206	pyrimidine nucleobase metabolic process	1.36e-02	1.00e+00	6.187	1	2	22
GO:0033574	response to testosterone	1.36e-02	1.00e+00	6.187	1	2	22
GO:0030863	cortical cytoskeleton	1.36e-02	1.00e+00	6.187	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.36e-02	1.00e+00	6.187	1	4	22
GO:0043234	protein complex	1.37e-02	1.00e+00	3.442	2	18	295
GO:0043044	ATP-dependent chromatin remodeling	1.43e-02	1.00e+00	6.123	1	4	23
GO:0005844	polysome	1.43e-02	1.00e+00	6.123	1	4	23
GO:0043236	laminin binding	1.43e-02	1.00e+00	6.123	1	1	23
GO:0019901	protein kinase binding	1.57e-02	1.00e+00	3.338	2	21	317
GO:0015991	ATP hydrolysis coupled proton transport	1.61e-02	1.00e+00	5.946	1	4	26
GO:0019843	rRNA binding	1.67e-02	1.00e+00	5.891	1	3	27
GO:0043022	ribosome binding	1.67e-02	1.00e+00	5.891	1	3	27
GO:0050661	NADP binding	1.67e-02	1.00e+00	5.891	1	2	27
GO:0031492	nucleosomal DNA binding	1.67e-02	1.00e+00	5.891	1	4	27
GO:0019894	kinesin binding	1.73e-02	1.00e+00	5.839	1	1	28
GO:0015992	proton transport	1.80e-02	1.00e+00	5.788	1	3	29
GO:0033572	transferrin transport	1.86e-02	1.00e+00	5.739	1	5	30
GO:0051701	interaction with host	1.98e-02	1.00e+00	5.646	1	4	32
GO:0005925	focal adhesion	2.05e-02	1.00e+00	3.130	2	19	366
GO:0001895	retina homeostasis	2.10e-02	1.00e+00	5.559	1	1	34
GO:0034332	adherens junction organization	2.22e-02	1.00e+00	5.476	1	1	36
GO:0090382	phagosome maturation	2.22e-02	1.00e+00	5.476	1	5	36
GO:0018107	peptidyl-threonine phosphorylation	2.29e-02	1.00e+00	5.437	1	4	37
GO:0051084	'de novo' posttranslational protein folding	2.29e-02	1.00e+00	5.437	1	4	37
GO:0005902	microvillus	2.35e-02	1.00e+00	5.398	1	2	38
GO:0070527	platelet aggregation	2.35e-02	1.00e+00	5.398	1	2	38
GO:0008026	ATP-dependent helicase activity	2.41e-02	1.00e+00	5.361	1	3	39
GO:0007595	lactation	2.41e-02	1.00e+00	5.361	1	2	39
GO:0043195	terminal bouton	2.53e-02	1.00e+00	5.289	1	1	41
GO:0021762	substantia nigra development	2.71e-02	1.00e+00	5.187	1	2	44
GO:0045727	positive regulation of translation	2.71e-02	1.00e+00	5.187	1	3	44
GO:0022625	cytosolic large ribosomal subunit	3.02e-02	1.00e+00	5.031	1	6	49
GO:0035690	cellular response to drug	3.02e-02	1.00e+00	5.031	1	2	49
GO:0031100	organ regeneration	3.08e-02	1.00e+00	5.002	1	4	50
GO:0006879	cellular iron ion homeostasis	3.14e-02	1.00e+00	4.974	1	4	51
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.26e-02	1.00e+00	4.918	1	5	53
GO:0002244	hematopoietic progenitor cell differentiation	3.32e-02	1.00e+00	4.891	1	1	54
GO:0045216	cell-cell junction organization	3.32e-02	1.00e+00	4.891	1	2	54
GO:0012505	endomembrane system	3.44e-02	1.00e+00	4.839	1	2	56
GO:0005840	ribosome	3.56e-02	1.00e+00	4.788	1	1	58
GO:0042995	cell projection	3.68e-02	1.00e+00	4.739	1	6	60
GO:0034329	cell junction assembly	4.17e-02	1.00e+00	4.559	1	1	68
GO:0055086	nucleobase-containing small molecule metabolic process	4.29e-02	1.00e+00	4.517	1	2	70
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.53e-02	1.00e+00	4.437	1	6	74
GO:0001889	liver development	4.70e-02	1.00e+00	4.379	1	4	77
GO:0007565	female pregnancy	4.76e-02	1.00e+00	4.361	1	1	78
GO:0001726	ruffle	4.88e-02	1.00e+00	4.324	1	4	80
GO:0042470	melanosome	5.54e-02	1.00e+00	4.138	1	9	91
GO:0016363	nuclear matrix	5.54e-02	1.00e+00	4.138	1	12	91
GO:0006928	cellular component movement	5.54e-02	1.00e+00	4.138	1	7	91
GO:0005200	structural constituent of cytoskeleton	5.54e-02	1.00e+00	4.138	1	8	91
GO:0001649	osteoblast differentiation	5.60e-02	1.00e+00	4.123	1	6	92
GO:0014069	postsynaptic density	6.37e-02	1.00e+00	3.932	1	3	105
GO:0072562	blood microparticle	6.72e-02	1.00e+00	3.852	1	3	111
GO:0006325	chromatin organization	7.13e-02	1.00e+00	3.764	1	5	118
GO:0000790	nuclear chromatin	7.77e-02	1.00e+00	3.635	1	9	129
GO:0007507	heart development	8.35e-02	1.00e+00	3.527	1	7	139
GO:0008286	insulin receptor signaling pathway	8.52e-02	1.00e+00	3.496	1	7	142
GO:0006457	protein folding	8.58e-02	1.00e+00	3.486	1	7	143
GO:0061024	membrane organization	8.69e-02	1.00e+00	3.466	1	7	145
GO:0010628	positive regulation of gene expression	8.75e-02	1.00e+00	3.456	1	5	146
GO:0046777	protein autophosphorylation	9.44e-02	1.00e+00	3.342	1	7	158
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.84e-02	1.00e+00	3.280	1	7	165
GO:0030424	axon	9.90e-02	1.00e+00	3.271	1	4	166
GO:0004672	protein kinase activity	1.05e-01	1.00e+00	3.179	1	6	177
GO:0003924	GTPase activity	1.16e-01	1.00e+00	3.024	1	12	197
GO:0005765	lysosomal membrane	1.20e-01	1.00e+00	2.981	1	5	203
GO:0006184	GTP catabolic process	1.26e-01	1.00e+00	2.905	1	12	214
GO:0043025	neuronal cell body	1.43e-01	1.00e+00	2.710	1	9	245
GO:0005975	carbohydrate metabolic process	1.47e-01	1.00e+00	2.663	1	9	253
GO:0019899	enzyme binding	1.60e-01	1.00e+00	2.532	1	12	277
GO:0005856	cytoskeleton	1.68e-01	1.00e+00	2.461	1	12	291
GO:0006200	ATP catabolic process	1.68e-01	1.00e+00	2.456	1	15	292
GO:0044281	small molecule metabolic process	1.71e-01	1.00e+00	1.404	2	58	1211
GO:0005525	GTP binding	1.78e-01	1.00e+00	2.370	1	12	310
GO:0043231	intracellular membrane-bounded organelle	1.82e-01	1.00e+00	2.333	1	9	318
GO:0007411	axon guidance	1.82e-01	1.00e+00	2.329	1	13	319
GO:0003723	RNA binding	1.94e-01	1.00e+00	2.228	1	20	342
GO:0007155	cell adhesion	2.08e-01	1.00e+00	2.119	1	6	369
GO:0055114	oxidation-reduction process	2.34e-01	1.00e+00	1.932	1	12	420
GO:0055085	transmembrane transport	2.41e-01	1.00e+00	1.881	1	10	435
GO:0007596	blood coagulation	2.51e-01	1.00e+00	1.816	1	18	455
GO:0042802	identical protein binding	2.65e-01	1.00e+00	1.727	1	20	484
GO:0005515	protein binding	3.04e-01	1.00e+00	0.412	5	184	6024
GO:0005634	nucleus	3.08e-01	1.00e+00	0.492	4	136	4559
GO:0045087	innate immune response	3.16e-01	1.00e+00	1.427	1	24	596
GO:0005737	cytoplasm	4.31e-01	1.00e+00	0.352	3	110	3767
GO:0005615	extracellular space	4.61e-01	1.00e+00	0.744	1	17	957
GO:0008270	zinc ion binding	4.75e-01	1.00e+00	0.685	1	12	997
GO:0005886	plasma membrane	4.98e-01	1.00e+00	0.312	2	45	2582
GO:0005654	nucleoplasm	5.04e-01	1.00e+00	0.567	1	76	1082
GO:0005730	nucleolus	6.63e-01	1.00e+00	-0.034	1	69	1641
GO:0016021	integral component of membrane	7.36e-01	1.00e+00	-0.307	1	27	1982

Wolf-ratios-Mammosphere-Adherent

int-snw-317781

Statistics

Genes (9)

Interactions (13)

Related GO terms (153)