int-snw-2182

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.935	1.60e-15	2.46e-03	3.99e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-2182 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
CAD	790	17	0.807	1.007	333	-	-
ACO2	50	50	1.000	1.076	191	Yes	-
[ ACSL4 ]	2182	1	0.411	0.935	41	Yes	-
ATP6V1B2	526	44	0.881	1.076	278	-	-
RBX1	9978	97	1.185	1.151	139	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACO2	50	ACSL4	2182	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
CAD	790	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
ATP6V1B2	526	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
ACSL4	2182	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
ACSL4	2182	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
CAD	790	ACSL4	2182	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2	526	ACSL4	2182	pp	--	int.I2D: IntAct_Yeast

Related GO terms (144)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004151	dihydroorotase activity	4.16e-04	1.00e+00	11.231	1	1	1
GO:0004070	aspartate carbamoyltransferase activity	4.16e-04	1.00e+00	11.231	1	1	1
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	4.16e-04	1.00e+00	11.231	1	1	1
GO:0070335	aspartate binding	4.16e-04	1.00e+00	11.231	1	1	1
GO:0047676	arachidonate-CoA ligase activity	4.16e-04	1.00e+00	11.231	1	1	1
GO:0032307	negative regulation of prostaglandin secretion	4.16e-04	1.00e+00	11.231	1	1	1
GO:0051538	3 iron, 4 sulfur cluster binding	8.32e-04	1.00e+00	10.231	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.32e-04	1.00e+00	10.231	1	1	2
GO:0003994	aconitate hydratase activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0005055	laminin receptor activity	8.32e-04	1.00e+00	10.231	1	1	2
GO:0006407	rRNA export from nucleus	8.32e-04	1.00e+00	10.231	1	1	2
GO:0070409	carbamoyl phosphate biosynthetic process	8.32e-04	1.00e+00	10.231	1	1	2
GO:0070672	response to interleukin-15	1.25e-03	1.00e+00	9.646	1	1	3
GO:0044205	'de novo' UMP biosynthetic process	1.25e-03	1.00e+00	9.646	1	1	3
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	1.25e-03	1.00e+00	9.646	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.66e-03	1.00e+00	9.231	1	1	4
GO:0030686	90S preribosome	1.66e-03	1.00e+00	9.231	1	1	4
GO:0006543	glutamine catabolic process	1.66e-03	1.00e+00	9.231	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	1.66e-03	1.00e+00	9.231	1	1	4
GO:0019788	NEDD8 ligase activity	1.66e-03	1.00e+00	9.231	1	1	4
GO:0051414	response to cortisol	2.08e-03	1.00e+00	8.909	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	2.08e-03	1.00e+00	8.909	1	3	5
GO:0031461	cullin-RING ubiquitin ligase complex	2.08e-03	1.00e+00	8.909	1	1	5
GO:0006102	isocitrate metabolic process	2.08e-03	1.00e+00	8.909	1	1	5
GO:0030891	VCB complex	2.08e-03	1.00e+00	8.909	1	2	5
GO:0044233	ER-mitochondrion membrane contact site	2.08e-03	1.00e+00	8.909	1	1	5
GO:0060996	dendritic spine development	2.49e-03	1.00e+00	8.646	1	1	6
GO:0046134	pyrimidine nucleoside biosynthetic process	2.49e-03	1.00e+00	8.646	1	1	6
GO:0006101	citrate metabolic process	2.49e-03	1.00e+00	8.646	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	2.49e-03	1.00e+00	8.646	1	1	6
GO:0060136	embryonic process involved in female pregnancy	2.91e-03	1.00e+00	8.424	1	1	7
GO:0033180	proton-transporting V-type ATPase, V1 domain	2.91e-03	1.00e+00	8.424	1	2	7
GO:0000028	ribosomal small subunit assembly	2.91e-03	1.00e+00	8.424	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	2.91e-03	1.00e+00	8.424	1	2	7
GO:0031957	very long-chain fatty acid-CoA ligase activity	2.91e-03	1.00e+00	8.424	1	1	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	3.32e-03	1.00e+00	8.231	1	2	8
GO:0015908	fatty acid transport	3.32e-03	1.00e+00	8.231	1	1	8
GO:0045116	protein neddylation	3.32e-03	1.00e+00	8.231	1	2	8
GO:0008610	lipid biosynthetic process	3.74e-03	1.00e+00	8.061	1	1	9
GO:0006228	UTP biosynthetic process	3.74e-03	1.00e+00	8.061	1	1	9
GO:0014075	response to amine	3.74e-03	1.00e+00	8.061	1	1	9
GO:0031000	response to caffeine	3.74e-03	1.00e+00	8.061	1	2	9
GO:0004467	long-chain fatty acid-CoA ligase activity	3.74e-03	1.00e+00	8.061	1	1	9
GO:0043025	neuronal cell body	4.12e-03	1.00e+00	4.294	2	9	245
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	5.40e-03	1.00e+00	7.531	1	3	13
GO:0001676	long-chain fatty acid metabolic process	5.81e-03	1.00e+00	7.424	1	1	14
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6.22e-03	1.00e+00	7.324	1	3	15
GO:0046034	ATP metabolic process	6.22e-03	1.00e+00	7.324	1	1	15
GO:0006541	glutamine metabolic process	7.05e-03	1.00e+00	7.144	1	1	17
GO:0017144	drug metabolic process	7.47e-03	1.00e+00	7.061	1	1	18
GO:0015078	hydrogen ion transmembrane transporter activity	7.88e-03	1.00e+00	6.983	1	3	19
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	7.88e-03	1.00e+00	6.983	1	1	19
GO:0070062	extracellular vesicular exosome	8.64e-03	1.00e+00	2.002	4	104	2400
GO:0071364	cellular response to epidermal growth factor stimulus	8.71e-03	1.00e+00	6.839	1	1	21
GO:0006206	pyrimidine nucleobase metabolic process	9.12e-03	1.00e+00	6.772	1	2	22
GO:0033574	response to testosterone	9.12e-03	1.00e+00	6.772	1	2	22
GO:0031463	Cul3-RING ubiquitin ligase complex	9.53e-03	1.00e+00	6.708	1	3	23
GO:0043236	laminin binding	9.53e-03	1.00e+00	6.708	1	1	23
GO:0006513	protein monoubiquitination	9.53e-03	1.00e+00	6.708	1	1	23
GO:0044281	small molecule metabolic process	9.73e-03	1.00e+00	2.574	3	58	1211
GO:0005829	cytosol	9.98e-03	1.00e+00	1.946	4	132	2496
GO:0015991	ATP hydrolysis coupled proton transport	1.08e-02	1.00e+00	6.531	1	4	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.08e-02	1.00e+00	6.531	1	3	26
GO:0043022	ribosome binding	1.12e-02	1.00e+00	6.476	1	3	27
GO:0006099	tricarboxylic acid cycle	1.16e-02	1.00e+00	6.424	1	4	28
GO:0005524	ATP binding	1.18e-02	1.00e+00	2.474	3	60	1298
GO:0019005	SCF ubiquitin ligase complex	1.20e-02	1.00e+00	6.373	1	1	29
GO:0015992	proton transport	1.20e-02	1.00e+00	6.373	1	3	29
GO:0019432	triglyceride biosynthetic process	1.24e-02	1.00e+00	6.324	1	3	30
GO:0033572	transferrin transport	1.24e-02	1.00e+00	6.324	1	5	30
GO:0051701	interaction with host	1.32e-02	1.00e+00	6.231	1	4	32
GO:0051539	4 iron, 4 sulfur cluster binding	1.45e-02	1.00e+00	6.102	1	3	35
GO:0090382	phagosome maturation	1.49e-02	1.00e+00	6.061	1	5	36
GO:0018107	peptidyl-threonine phosphorylation	1.53e-02	1.00e+00	6.022	1	4	37
GO:0005902	microvillus	1.57e-02	1.00e+00	5.983	1	2	38
GO:0022627	cytosolic small ribosomal subunit	1.61e-02	1.00e+00	5.946	1	4	39
GO:0007595	lactation	1.61e-02	1.00e+00	5.946	1	2	39
GO:0043195	terminal bouton	1.69e-02	1.00e+00	5.874	1	1	41
GO:0016032	viral process	1.86e-02	1.00e+00	3.170	2	55	534
GO:0005778	peroxisomal membrane	1.94e-02	1.00e+00	5.677	1	1	47
GO:0005811	lipid particle	1.94e-02	1.00e+00	5.677	1	2	47
GO:0035690	cellular response to drug	2.02e-02	1.00e+00	5.616	1	2	49
GO:0006091	generation of precursor metabolites and energy	2.06e-02	1.00e+00	5.587	1	3	50
GO:0031100	organ regeneration	2.06e-02	1.00e+00	5.587	1	4	50
GO:0006879	cellular iron ion homeostasis	2.10e-02	1.00e+00	5.559	1	4	51
GO:0012505	endomembrane system	2.31e-02	1.00e+00	5.424	1	2	56
GO:0016020	membrane	2.41e-02	1.00e+00	2.101	3	90	1681
GO:0042995	cell projection	2.47e-02	1.00e+00	5.324	1	6	60
GO:0030307	positive regulation of cell growth	2.84e-02	1.00e+00	5.123	1	3	69
GO:0055086	nucleobase-containing small molecule metabolic process	2.88e-02	1.00e+00	5.102	1	2	70
GO:0007584	response to nutrient	2.92e-02	1.00e+00	5.081	1	4	71
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	3.08e-02	1.00e+00	5.002	1	2	75
GO:0001889	liver development	3.16e-02	1.00e+00	4.964	1	4	77
GO:0007565	female pregnancy	3.20e-02	1.00e+00	4.946	1	1	78
GO:0001726	ruffle	3.28e-02	1.00e+00	4.909	1	4	80
GO:0019083	viral transcription	3.32e-02	1.00e+00	4.891	1	10	81
GO:0006415	translational termination	3.57e-02	1.00e+00	4.788	1	10	87
GO:0006629	lipid metabolic process	3.69e-02	1.00e+00	4.739	1	5	90
GO:0042470	melanosome	3.73e-02	1.00e+00	4.723	1	9	91
GO:0016363	nuclear matrix	3.73e-02	1.00e+00	4.723	1	12	91
GO:0071456	cellular response to hypoxia	3.77e-02	1.00e+00	4.708	1	6	92
GO:0006414	translational elongation	3.81e-02	1.00e+00	4.692	1	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	4.25e-02	1.00e+00	4.531	1	10	104
GO:0005506	iron ion binding	4.29e-02	1.00e+00	4.517	1	4	105
GO:0005741	mitochondrial outer membrane	4.29e-02	1.00e+00	4.517	1	7	105
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.65e-02	1.00e+00	4.398	1	11	114
GO:0019058	viral life cycle	4.69e-02	1.00e+00	4.386	1	13	115
GO:0044237	cellular metabolic process	4.77e-02	1.00e+00	4.361	1	5	117
GO:0007219	Notch signaling pathway	4.89e-02	1.00e+00	4.324	1	5	120
GO:0006413	translational initiation	5.33e-02	1.00e+00	4.198	1	17	131
GO:0044255	cellular lipid metabolic process	5.41e-02	1.00e+00	4.176	1	6	133
GO:0003735	structural constituent of ribosome	5.57e-02	1.00e+00	4.133	1	10	137
GO:0007507	heart development	5.65e-02	1.00e+00	4.112	1	7	139
GO:0008286	insulin receptor signaling pathway	5.76e-02	1.00e+00	4.081	1	7	142
GO:0008270	zinc ion binding	5.94e-02	1.00e+00	2.270	2	12	997
GO:0046777	protein autophosphorylation	6.40e-02	1.00e+00	3.927	1	7	158
GO:0004672	protein kinase activity	7.14e-02	1.00e+00	3.764	1	6	177
GO:0031625	ubiquitin protein ligase binding	7.18e-02	1.00e+00	3.755	1	14	178
GO:0032403	protein complex binding	7.38e-02	1.00e+00	3.715	1	10	183
GO:0005765	lysosomal membrane	8.15e-02	1.00e+00	3.566	1	5	203
GO:0016071	mRNA metabolic process	8.93e-02	1.00e+00	3.430	1	31	223
GO:0005759	mitochondrial matrix	9.12e-02	1.00e+00	3.398	1	14	228
GO:0006412	translation	9.20e-02	1.00e+00	3.386	1	20	230
GO:0016070	RNA metabolic process	9.85e-02	1.00e+00	3.283	1	32	247
GO:0004842	ubiquitin-protein transferase activity	1.02e-01	1.00e+00	3.237	1	6	255
GO:0006281	DNA repair	1.04e-01	1.00e+00	3.203	1	18	261
GO:0019899	enzyme binding	1.10e-01	1.00e+00	3.117	1	12	277
GO:0043234	protein complex	1.17e-01	1.00e+00	3.027	1	18	295
GO:0016567	protein ubiquitination	1.17e-01	1.00e+00	3.027	1	5	295
GO:0043231	intracellular membrane-bounded organelle	1.25e-01	1.00e+00	2.918	1	9	318
GO:0007155	cell adhesion	1.44e-01	1.00e+00	2.704	1	6	369
GO:0055085	transmembrane transport	1.68e-01	1.00e+00	2.466	1	10	435
GO:0044267	cellular protein metabolic process	1.82e-01	1.00e+00	2.342	1	29	474
GO:0042802	identical protein binding	1.85e-01	1.00e+00	2.312	1	20	484
GO:0016021	integral component of membrane	1.94e-01	1.00e+00	1.278	2	27	1982
GO:0005789	endoplasmic reticulum membrane	2.15e-01	1.00e+00	2.076	1	16	570
GO:0010467	gene expression	2.48e-01	1.00e+00	1.845	1	59	669
GO:0005634	nucleus	2.86e-01	1.00e+00	0.662	3	136	4559
GO:0005886	plasma membrane	2.93e-01	1.00e+00	0.897	2	45	2582
GO:0005739	mitochondrion	3.50e-01	1.00e+00	1.268	1	28	998
GO:0044822	poly(A) RNA binding	3.66e-01	1.00e+00	1.187	1	49	1056
GO:0005654	nucleoplasm	3.74e-01	1.00e+00	1.152	1	76	1082
GO:0005737	cytoplasm	4.92e-01	1.00e+00	0.352	2	110	3767
GO:0005515	protein binding	7.93e-01	1.00e+00	-0.325	2	184	6024

Wolf-ratios-Mammosphere-Adherent

int-snw-2182

Statistics

Genes (6)

Interactions (7)

Related GO terms (144)