int-snw-2098

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.953	3.31e-16	1.67e-03	3.02e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-2098 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ADH5	128	5	0.633	0.994	43	Yes	-
EEF2	1938	27	0.890	1.043	301	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
[ ESD ]	2098	1	-0.032	0.953	36	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (12)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
EEF2	1938	ESD	2098	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
ESD	2098	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
EEF2	1938	PGD	5226	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
ADH5	128	ESD	2098	pp	--	int.I2D: YeastMedium
ACTB	60	EEF2	1938	pp	--	int.I2D: YeastLow, IntAct_Yeast
ESD	2098	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (145)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0070062	extracellular vesicular exosome	9.66e-08	1.39e-03	2.587	9	104	2400
GO:0006414	translational elongation	1.99e-07	2.87e-03	6.107	4	13	93
GO:0046294	formaldehyde catabolic process	3.46e-07	4.99e-03	10.646	2	2	2
GO:0044267	cellular protein metabolic process	4.24e-06	6.12e-02	4.079	5	29	474
GO:0016071	mRNA metabolic process	6.60e-06	9.51e-02	4.845	4	31	223
GO:0006412	translation	7.46e-06	1.08e-01	4.801	4	20	230
GO:0016070	RNA metabolic process	9.89e-06	1.43e-01	4.698	4	32	247
GO:0019083	viral transcription	1.40e-05	2.02e-01	5.891	3	10	81
GO:0006415	translational termination	1.73e-05	2.50e-01	5.788	3	10	87
GO:0010467	gene expression	2.28e-05	3.29e-01	3.582	5	59	669
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.96e-05	4.28e-01	5.531	3	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.90e-05	5.63e-01	5.398	3	11	114
GO:0019058	viral life cycle	4.01e-05	5.78e-01	5.386	3	13	115
GO:0006413	translational initiation	5.91e-05	8.52e-01	5.198	3	17	131
GO:0003735	structural constituent of ribosome	6.75e-05	9.74e-01	5.133	3	10	137
GO:0005829	cytosol	1.20e-04	1.00e+00	2.168	7	132	2496
GO:0016020	membrane	1.53e-04	1.00e+00	2.516	6	90	1681
GO:0016032	viral process	2.02e-04	1.00e+00	3.585	4	55	534
GO:0022627	cytosolic small ribosomal subunit	2.53e-04	1.00e+00	6.361	2	4	39
GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity	6.24e-04	1.00e+00	10.646	1	1	1
GO:0018467	formaldehyde dehydrogenase activity	6.24e-04	1.00e+00	10.646	1	1	1
GO:0019521	D-gluconate metabolic process	6.24e-04	1.00e+00	10.646	1	1	1
GO:0018738	S-formylglutathione hydrolase activity	6.24e-04	1.00e+00	10.646	1	1	1
GO:0047374	methylumbelliferyl-acetate deacetylase activity	1.25e-03	1.00e+00	9.646	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.25e-03	1.00e+00	9.646	1	1	2
GO:0019322	pentose biosynthetic process	1.25e-03	1.00e+00	9.646	1	2	2
GO:0005055	laminin receptor activity	1.25e-03	1.00e+00	9.646	1	1	2
GO:0006407	rRNA export from nucleus	1.25e-03	1.00e+00	9.646	1	1	2
GO:0018119	peptidyl-cysteine S-nitrosylation	1.87e-03	1.00e+00	9.061	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	1.87e-03	1.00e+00	9.061	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.87e-03	1.00e+00	9.061	1	1	3
GO:0030529	ribonucleoprotein complex	2.08e-03	1.00e+00	4.839	2	8	112
GO:0006068	ethanol catabolic process	2.49e-03	1.00e+00	8.646	1	1	4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.49e-03	1.00e+00	8.646	1	1	4
GO:0030686	90S preribosome	2.49e-03	1.00e+00	8.646	1	1	4
GO:0051409	response to nitrosative stress	2.49e-03	1.00e+00	8.646	1	1	4
GO:0044822	poly(A) RNA binding	2.67e-03	1.00e+00	2.602	4	49	1056
GO:0043248	proteasome assembly	3.12e-03	1.00e+00	8.324	1	1	5
GO:0004022	alcohol dehydrogenase (NAD) activity	3.12e-03	1.00e+00	8.324	1	1	5
GO:0030957	Tat protein binding	3.74e-03	1.00e+00	8.061	1	3	6
GO:0000028	ribosomal small subunit assembly	4.36e-03	1.00e+00	7.839	1	1	7
GO:0003016	respiratory system process	4.98e-03	1.00e+00	7.646	1	1	8
GO:0070688	MLL5-L complex	4.98e-03	1.00e+00	7.646	1	1	8
GO:0008494	translation activator activity	5.60e-03	1.00e+00	7.476	1	1	9
GO:0006098	pentose-phosphate shunt	6.22e-03	1.00e+00	7.324	1	4	10
GO:0052689	carboxylic ester hydrolase activity	6.22e-03	1.00e+00	7.324	1	1	10
GO:0006069	ethanol oxidation	6.22e-03	1.00e+00	7.324	1	1	10
GO:0051775	response to redox state	6.22e-03	1.00e+00	7.324	1	1	10
GO:0016788	hydrolase activity, acting on ester bonds	6.85e-03	1.00e+00	7.187	1	1	11
GO:0005838	proteasome regulatory particle	7.47e-03	1.00e+00	7.061	1	7	12
GO:0042273	ribosomal large subunit biogenesis	8.09e-03	1.00e+00	6.946	1	4	13
GO:0005504	fatty acid binding	8.09e-03	1.00e+00	6.946	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	8.70e-03	1.00e+00	6.839	1	4	14
GO:0050998	nitric-oxide synthase binding	9.94e-03	1.00e+00	6.646	1	1	16
GO:0045777	positive regulation of blood pressure	1.06e-02	1.00e+00	6.559	1	1	17
GO:0003746	translation elongation factor activity	1.06e-02	1.00e+00	6.559	1	3	17
GO:0022624	proteasome accessory complex	1.06e-02	1.00e+00	6.559	1	8	17
GO:0048863	stem cell differentiation	1.18e-02	1.00e+00	6.398	1	1	19
GO:0030863	cortical cytoskeleton	1.36e-02	1.00e+00	6.187	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.36e-02	1.00e+00	6.187	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.43e-02	1.00e+00	6.123	1	4	23
GO:0005844	polysome	1.43e-02	1.00e+00	6.123	1	4	23
GO:0043236	laminin binding	1.43e-02	1.00e+00	6.123	1	1	23
GO:0019901	protein kinase binding	1.57e-02	1.00e+00	3.338	2	21	317
GO:0019843	rRNA binding	1.67e-02	1.00e+00	5.891	1	3	27
GO:0043022	ribosome binding	1.67e-02	1.00e+00	5.891	1	3	27
GO:0050661	NADP binding	1.67e-02	1.00e+00	5.891	1	2	27
GO:0031492	nucleosomal DNA binding	1.67e-02	1.00e+00	5.891	1	4	27
GO:0019894	kinesin binding	1.73e-02	1.00e+00	5.839	1	1	28
GO:0005925	focal adhesion	2.05e-02	1.00e+00	3.130	2	19	366
GO:0001895	retina homeostasis	2.10e-02	1.00e+00	5.559	1	1	34
GO:0034332	adherens junction organization	2.22e-02	1.00e+00	5.476	1	1	36
GO:0051084	'de novo' posttranslational protein folding	2.29e-02	1.00e+00	5.437	1	4	37
GO:0070527	platelet aggregation	2.35e-02	1.00e+00	5.398	1	2	38
GO:0021762	substantia nigra development	2.71e-02	1.00e+00	5.187	1	2	44
GO:0045727	positive regulation of translation	2.71e-02	1.00e+00	5.187	1	3	44
GO:0001523	retinoid metabolic process	2.96e-02	1.00e+00	5.061	1	2	48
GO:0022625	cytosolic large ribosomal subunit	3.02e-02	1.00e+00	5.031	1	6	49
GO:0006521	regulation of cellular amino acid metabolic process	3.08e-02	1.00e+00	5.002	1	17	50
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.26e-02	1.00e+00	4.918	1	5	53
GO:0005634	nucleus	3.27e-02	1.00e+00	1.077	6	136	4559
GO:0002244	hematopoietic progenitor cell differentiation	3.32e-02	1.00e+00	4.891	1	1	54
GO:0045216	cell-cell junction organization	3.32e-02	1.00e+00	4.891	1	2	54
GO:0005840	ribosome	3.56e-02	1.00e+00	4.788	1	1	58
GO:0000502	proteasome complex	3.56e-02	1.00e+00	4.788	1	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.92e-02	1.00e+00	4.646	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.98e-02	1.00e+00	4.624	1	22	65
GO:0009055	electron carrier activity	3.98e-02	1.00e+00	4.624	1	1	65
GO:0034329	cell junction assembly	4.17e-02	1.00e+00	4.559	1	1	68
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.29e-02	1.00e+00	4.517	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	4.41e-02	1.00e+00	4.476	1	20	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.53e-02	1.00e+00	4.437	1	6	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.53e-02	1.00e+00	4.437	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.59e-02	1.00e+00	4.417	1	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.82e-02	1.00e+00	4.342	1	23	79
GO:0006928	cellular component movement	5.54e-02	1.00e+00	4.138	1	7	91
GO:0005200	structural constituent of cytoskeleton	5.54e-02	1.00e+00	4.138	1	8	91
GO:0001649	osteoblast differentiation	5.60e-02	1.00e+00	4.123	1	6	92
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	5.60e-02	1.00e+00	4.123	1	21	92
GO:0006364	rRNA processing	5.72e-02	1.00e+00	4.092	1	6	94
GO:0014069	postsynaptic density	6.37e-02	1.00e+00	3.932	1	3	105
GO:0016023	cytoplasmic membrane-bounded vesicle	6.37e-02	1.00e+00	3.932	1	5	105
GO:0072562	blood microparticle	6.72e-02	1.00e+00	3.852	1	3	111
GO:0000209	protein polyubiquitination	7.01e-02	1.00e+00	3.788	1	20	116
GO:0007568	aging	7.07e-02	1.00e+00	3.776	1	3	117
GO:0006325	chromatin organization	7.13e-02	1.00e+00	3.764	1	5	118
GO:0032496	response to lipopolysaccharide	7.30e-02	1.00e+00	3.727	1	4	121
GO:0006511	ubiquitin-dependent protein catabolic process	7.60e-02	1.00e+00	3.669	1	5	126
GO:0000790	nuclear chromatin	7.77e-02	1.00e+00	3.635	1	9	129
GO:0006457	protein folding	8.58e-02	1.00e+00	3.486	1	7	143
GO:0061024	membrane organization	8.69e-02	1.00e+00	3.466	1	7	145
GO:0010628	positive regulation of gene expression	8.75e-02	1.00e+00	3.456	1	5	146
GO:0000082	G1/S transition of mitotic cell cycle	8.92e-02	1.00e+00	3.427	1	32	149
GO:0042981	regulation of apoptotic process	8.98e-02	1.00e+00	3.417	1	24	150
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9.84e-02	1.00e+00	3.280	1	7	165
GO:0030424	axon	9.90e-02	1.00e+00	3.271	1	4	166
GO:0034641	cellular nitrogen compound metabolic process	1.02e-01	1.00e+00	3.228	1	20	171
GO:0003924	GTPase activity	1.16e-01	1.00e+00	3.024	1	12	197
GO:0005515	protein binding	1.20e-01	1.00e+00	0.675	6	184	6024
GO:0006184	GTP catabolic process	1.26e-01	1.00e+00	2.905	1	12	214
GO:0005654	nucleoplasm	1.42e-01	1.00e+00	1.567	2	76	1082
GO:0005975	carbohydrate metabolic process	1.47e-01	1.00e+00	2.663	1	9	253
GO:0005856	cytoskeleton	1.68e-01	1.00e+00	2.461	1	12	291
GO:0043234	protein complex	1.70e-01	1.00e+00	2.442	1	18	295
GO:0044281	small molecule metabolic process	1.71e-01	1.00e+00	1.404	2	58	1211
GO:0005525	GTP binding	1.78e-01	1.00e+00	2.370	1	12	310
GO:0007411	axon guidance	1.82e-01	1.00e+00	2.329	1	13	319
GO:0005737	cytoplasm	1.87e-01	1.00e+00	0.767	4	110	3767
GO:0003723	RNA binding	1.94e-01	1.00e+00	2.228	1	20	342
GO:0007155	cell adhesion	2.08e-01	1.00e+00	2.119	1	6	369
GO:0008150	biological_process	2.18e-01	1.00e+00	2.043	1	3	389
GO:0000278	mitotic cell cycle	2.19e-01	1.00e+00	2.035	1	48	391
GO:0055114	oxidation-reduction process	2.34e-01	1.00e+00	1.932	1	12	420
GO:0043066	negative regulation of apoptotic process	2.36e-01	1.00e+00	1.918	1	31	424
GO:0007596	blood coagulation	2.51e-01	1.00e+00	1.816	1	18	455
GO:0006915	apoptotic process	2.98e-01	1.00e+00	1.530	1	33	555
GO:0042803	protein homodimerization activity	3.16e-01	1.00e+00	1.429	1	12	595
GO:0045087	innate immune response	3.16e-01	1.00e+00	1.427	1	24	596
GO:0005794	Golgi apparatus	3.22e-01	1.00e+00	1.393	1	15	610
GO:0005615	extracellular space	4.61e-01	1.00e+00	0.744	1	17	957
GO:0008270	zinc ion binding	4.75e-01	1.00e+00	0.685	1	12	997
GO:0005739	mitochondrion	4.76e-01	1.00e+00	0.683	1	28	998
GO:0005886	plasma membrane	4.98e-01	1.00e+00	0.312	2	45	2582
GO:0005524	ATP binding	5.72e-01	1.00e+00	0.304	1	60	1298
GO:0005730	nucleolus	6.63e-01	1.00e+00	-0.034	1	69	1641

Wolf-ratios-Mammosphere-Adherent

int-snw-2098

Statistics

Genes (9)

Interactions (12)

Related GO terms (145)