int-snw-2091

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.151	4.62e-25	8.15e-06	4.30e-04

wolf-screen-ratio-mammosphere-adherent-int-snw-2091 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPA2	6118	98	1.250	1.151	69	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
[ FBL ]	2091	7	0.839	1.151	65	Yes	-
RBX1	9978	97	1.185	1.151	139	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	FBL	2091	pp	--	int.I2D: MINT
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct

Related GO terms (133)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:1990259	histone-glutamine methyltransferase activity	3.47e-04	1.00e+00	11.494	1	1	1
GO:1990258	histone glutamine methylation	3.47e-04	1.00e+00	11.494	1	1	1
GO:0016074	snoRNA metabolic process	3.47e-04	1.00e+00	11.494	1	1	1
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6.93e-04	1.00e+00	10.494	1	1	2
GO:0005055	laminin receptor activity	6.93e-04	1.00e+00	10.494	1	1	2
GO:0006407	rRNA export from nucleus	6.93e-04	1.00e+00	10.494	1	1	2
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.39e-03	1.00e+00	9.494	1	1	4
GO:0030686	90S preribosome	1.39e-03	1.00e+00	9.494	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	1.39e-03	1.00e+00	9.494	1	1	4
GO:0019788	NEDD8 ligase activity	1.39e-03	1.00e+00	9.494	1	1	4
GO:0001652	granular component	1.39e-03	1.00e+00	9.494	1	1	4
GO:0031428	box C/D snoRNP complex	1.39e-03	1.00e+00	9.494	1	1	4
GO:0031625	ubiquitin protein ligase binding	1.48e-03	1.00e+00	5.018	2	14	178
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	1.73e-03	1.00e+00	9.172	1	3	5
GO:0031461	cullin-RING ubiquitin ligase complex	1.73e-03	1.00e+00	9.172	1	1	5
GO:0030891	VCB complex	1.73e-03	1.00e+00	9.172	1	2	5
GO:0000730	DNA recombinase assembly	1.73e-03	1.00e+00	9.172	1	1	5
GO:2000001	regulation of DNA damage checkpoint	1.73e-03	1.00e+00	9.172	1	1	5
GO:0030957	Tat protein binding	2.08e-03	1.00e+00	8.909	1	3	6
GO:0031466	Cul5-RING ubiquitin ligase complex	2.08e-03	1.00e+00	8.909	1	1	6
GO:0000028	ribosomal small subunit assembly	2.42e-03	1.00e+00	8.687	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	2.42e-03	1.00e+00	8.687	1	2	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	2.77e-03	1.00e+00	8.494	1	2	8
GO:0070688	MLL5-L complex	2.77e-03	1.00e+00	8.494	1	1	8
GO:0045116	protein neddylation	2.77e-03	1.00e+00	8.494	1	2	8
GO:0006281	DNA repair	3.15e-03	1.00e+00	4.466	2	18	261
GO:0010569	regulation of double-strand break repair via homologous recombination	3.46e-03	1.00e+00	8.172	1	1	10
GO:0005654	nucleoplasm	3.75e-03	1.00e+00	3.000	3	76	1082
GO:0031571	mitotic G1 DNA damage checkpoint	3.81e-03	1.00e+00	8.035	1	4	11
GO:0005662	DNA replication factor A complex	4.50e-03	1.00e+00	7.794	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	4.84e-03	1.00e+00	7.687	1	4	14
GO:0050998	nitric-oxide synthase binding	5.54e-03	1.00e+00	7.494	1	1	16
GO:0035861	site of double-strand break	6.23e-03	1.00e+00	7.324	1	1	18
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	6.57e-03	1.00e+00	7.246	1	1	19
GO:0006298	mismatch repair	6.92e-03	1.00e+00	7.172	1	3	20
GO:0032201	telomere maintenance via semi-conservative replication	7.26e-03	1.00e+00	7.102	1	5	21
GO:0000718	nucleotide-excision repair, DNA damage removal	7.26e-03	1.00e+00	7.102	1	4	21
GO:0006297	nucleotide-excision repair, DNA gap filling	7.60e-03	1.00e+00	7.035	1	3	22
GO:0030863	cortical cytoskeleton	7.60e-03	1.00e+00	7.035	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	7.60e-03	1.00e+00	7.035	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	7.95e-03	1.00e+00	6.971	1	4	23
GO:0031463	Cul3-RING ubiquitin ligase complex	7.95e-03	1.00e+00	6.971	1	3	23
GO:0043236	laminin binding	7.95e-03	1.00e+00	6.971	1	1	23
GO:0006513	protein monoubiquitination	7.95e-03	1.00e+00	6.971	1	1	23
GO:0000722	telomere maintenance via recombination	8.64e-03	1.00e+00	6.850	1	5	25
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	8.98e-03	1.00e+00	6.794	1	3	26
GO:0043022	ribosome binding	9.33e-03	1.00e+00	6.739	1	3	27
GO:0031492	nucleosomal DNA binding	9.33e-03	1.00e+00	6.739	1	4	27
GO:0019894	kinesin binding	9.67e-03	1.00e+00	6.687	1	1	28
GO:0019005	SCF ubiquitin ligase complex	1.00e-02	1.00e+00	6.636	1	1	29
GO:0044267	cellular protein metabolic process	1.01e-02	1.00e+00	3.605	2	29	474
GO:0006271	DNA strand elongation involved in DNA replication	1.04e-02	1.00e+00	6.587	1	7	30
GO:0001895	retina homeostasis	1.17e-02	1.00e+00	6.407	1	1	34
GO:0008033	tRNA processing	1.17e-02	1.00e+00	6.407	1	1	34
GO:0034332	adherens junction organization	1.24e-02	1.00e+00	6.324	1	1	36
GO:0005515	protein binding	1.27e-02	1.00e+00	1.260	5	184	6024
GO:0016032	viral process	1.27e-02	1.00e+00	3.433	2	55	534
GO:0051084	'de novo' posttranslational protein folding	1.28e-02	1.00e+00	6.285	1	4	37
GO:0006284	base-excision repair	1.28e-02	1.00e+00	6.285	1	3	37
GO:0070527	platelet aggregation	1.31e-02	1.00e+00	6.246	1	2	38
GO:0016020	membrane	1.32e-02	1.00e+00	2.364	3	90	1681
GO:0022627	cytosolic small ribosomal subunit	1.34e-02	1.00e+00	6.209	1	4	39
GO:0000781	chromosome, telomeric region	1.34e-02	1.00e+00	6.209	1	3	39
GO:0021762	substantia nigra development	1.52e-02	1.00e+00	6.035	1	2	44
GO:0015030	Cajal body	1.52e-02	1.00e+00	6.035	1	3	44
GO:0006283	transcription-coupled nucleotide-excision repair	1.58e-02	1.00e+00	5.971	1	7	46
GO:0003684	damaged DNA binding	1.69e-02	1.00e+00	5.879	1	7	49
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1.82e-02	1.00e+00	5.766	1	5	53
GO:0045216	cell-cell junction organization	1.86e-02	1.00e+00	5.739	1	2	54
GO:0000724	double-strand break repair via homologous recombination	1.89e-02	1.00e+00	5.713	1	3	55
GO:0000723	telomere maintenance	1.93e-02	1.00e+00	5.687	1	6	56
GO:0019903	protein phosphatase binding	2.13e-02	1.00e+00	5.540	1	4	62
GO:0006302	double-strand break repair	2.13e-02	1.00e+00	5.540	1	4	62
GO:0006289	nucleotide-excision repair	2.34e-02	1.00e+00	5.407	1	11	68
GO:0034329	cell junction assembly	2.34e-02	1.00e+00	5.407	1	1	68
GO:0003697	single-stranded DNA binding	2.34e-02	1.00e+00	5.407	1	5	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	2.54e-02	1.00e+00	5.285	1	6	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	2.57e-02	1.00e+00	5.265	1	2	75
GO:0019083	viral transcription	2.78e-02	1.00e+00	5.154	1	10	81
GO:0047485	protein N-terminus binding	2.95e-02	1.00e+00	5.068	1	5	86
GO:0006415	translational termination	2.98e-02	1.00e+00	5.051	1	10	87
GO:0016605	PML body	3.01e-02	1.00e+00	5.035	1	3	88
GO:0006928	cellular component movement	3.12e-02	1.00e+00	4.986	1	7	91
GO:0005200	structural constituent of cytoskeleton	3.12e-02	1.00e+00	4.986	1	8	91
GO:0001649	osteoblast differentiation	3.15e-02	1.00e+00	4.971	1	6	92
GO:0071456	cellular response to hypoxia	3.15e-02	1.00e+00	4.971	1	6	92
GO:0006414	translational elongation	3.18e-02	1.00e+00	4.955	1	13	93
GO:0006364	rRNA processing	3.22e-02	1.00e+00	4.940	1	6	94
GO:0070062	extracellular vesicular exosome	3.53e-02	1.00e+00	1.850	3	104	2400
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.55e-02	1.00e+00	4.794	1	10	104
GO:0014069	postsynaptic density	3.59e-02	1.00e+00	4.780	1	3	105
GO:0072562	blood microparticle	3.79e-02	1.00e+00	4.700	1	3	111
GO:0030529	ribonucleoprotein complex	3.82e-02	1.00e+00	4.687	1	8	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	3.89e-02	1.00e+00	4.661	1	11	114
GO:0019058	viral life cycle	3.92e-02	1.00e+00	4.649	1	13	115
GO:0005829	cytosol	3.93e-02	1.00e+00	1.794	3	132	2496
GO:0006325	chromatin organization	4.02e-02	1.00e+00	4.612	1	5	118
GO:0007219	Notch signaling pathway	4.09e-02	1.00e+00	4.587	1	5	120
GO:0006260	DNA replication	4.13e-02	1.00e+00	4.575	1	9	121
GO:0000790	nuclear chromatin	4.39e-02	1.00e+00	4.483	1	9	129
GO:0006413	translational initiation	4.46e-02	1.00e+00	4.461	1	17	131
GO:0044822	poly(A) RNA binding	4.62e-02	1.00e+00	2.450	2	49	1056
GO:0003735	structural constituent of ribosome	4.66e-02	1.00e+00	4.396	1	10	137
GO:0006457	protein folding	4.86e-02	1.00e+00	4.334	1	7	143
GO:0061024	membrane organization	4.93e-02	1.00e+00	4.314	1	7	145
GO:0000082	G1/S transition of mitotic cell cycle	5.06e-02	1.00e+00	4.275	1	32	149
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5.59e-02	1.00e+00	4.128	1	7	165
GO:0030424	axon	5.62e-02	1.00e+00	4.119	1	4	166
GO:0032403	protein complex binding	6.19e-02	1.00e+00	3.978	1	10	183
GO:0016071	mRNA metabolic process	7.50e-02	1.00e+00	3.693	1	31	223
GO:0006412	translation	7.72e-02	1.00e+00	3.649	1	20	230
GO:0016070	RNA metabolic process	8.28e-02	1.00e+00	3.546	1	32	247
GO:0004842	ubiquitin-protein transferase activity	8.53e-02	1.00e+00	3.500	1	6	255
GO:0019899	enzyme binding	9.24e-02	1.00e+00	3.380	1	12	277
GO:0005856	cytoskeleton	9.69e-02	1.00e+00	3.309	1	12	291
GO:0043234	protein complex	9.82e-02	1.00e+00	3.290	1	18	295
GO:0016567	protein ubiquitination	9.82e-02	1.00e+00	3.290	1	5	295
GO:0005730	nucleolus	1.02e-01	1.00e+00	1.814	2	69	1641
GO:0019901	protein kinase binding	1.05e-01	1.00e+00	3.186	1	21	317
GO:0007411	axon guidance	1.06e-01	1.00e+00	3.177	1	13	319
GO:0003723	RNA binding	1.13e-01	1.00e+00	3.076	1	20	342
GO:0005925	focal adhesion	1.21e-01	1.00e+00	2.978	1	19	366
GO:0007155	cell adhesion	1.22e-01	1.00e+00	2.967	1	6	369
GO:0000278	mitotic cell cycle	1.28e-01	1.00e+00	2.883	1	48	391
GO:0007596	blood coagulation	1.48e-01	1.00e+00	2.664	1	18	455
GO:0005634	nucleus	1.85e-01	1.00e+00	0.925	3	136	4559
GO:0045087	innate immune response	1.90e-01	1.00e+00	2.275	1	24	596
GO:0010467	gene expression	2.11e-01	1.00e+00	2.108	1	59	669
GO:0005615	extracellular space	2.91e-01	1.00e+00	1.592	1	17	957
GO:0008270	zinc ion binding	3.01e-01	1.00e+00	1.533	1	12	997
GO:0005524	ATP binding	3.76e-01	1.00e+00	1.152	1	60	1298
GO:0005737	cytoplasm	3.91e-01	1.00e+00	0.615	2	110	3767
GO:0005886	plasma membrane	6.27e-01	1.00e+00	0.160	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-2091

Statistics

Genes (5)

Interactions (4)

Related GO terms (133)