int-snw-1994

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.926	3.68e-15	3.01e-03	4.61e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-1994 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACTB	60	167	1.153	1.151	587	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACO2	50	50	1.000	1.076	191	Yes	-
ANP32B	10541	2	0.709	0.976	16	Yes	-
RUVBL1	8607	17	0.720	1.013	343	Yes	-
[ ELAVL1 ]	1994	1	0.517	0.926	88	Yes	-
CLTC	1213	35	0.884	1.138	247	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACO2	50	RUVBL1	8607	pp	--	int.I2D: YeastLow
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
ACTB	60	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
ELAVL1	1994	ANP32B	10541	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
ELAVL1	1994	RUVBL1	8607	pp	--	int.I2D: BioGrid
ACO2	50	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	RUVBL1	8607	pp	--	int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMD11	5717	RUVBL1	8607	pp	--	int.I2D: YeastLow
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
CLTC	1213	RUVBL1	8607	pp	--	int.I2D: MINT_Worm, IntAct_Worm

Related GO terms (169)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0035267	NuA4 histone acetyltransferase complex	2.44e-05	3.52e-01	8.009	2	4	14
GO:0016020	membrane	5.65e-05	8.14e-01	2.686	6	90	1681
GO:0016071	mRNA metabolic process	1.93e-04	1.00e+00	4.600	3	31	223
GO:0016070	RNA metabolic process	2.61e-04	1.00e+00	4.453	3	32	247
GO:0003725	double-stranded RNA binding	3.52e-04	1.00e+00	6.116	2	5	52
GO:0070062	extracellular vesicular exosome	4.35e-04	1.00e+00	2.172	6	104	2400
GO:0019901	protein kinase binding	5.43e-04	1.00e+00	4.093	3	21	317
GO:0006334	nucleosome assembly	6.75e-04	1.00e+00	5.646	2	2	72
GO:0051538	3 iron, 4 sulfur cluster binding	1.11e-03	1.00e+00	9.816	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.11e-03	1.00e+00	9.816	1	1	2
GO:0003994	aconitate hydratase activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0005055	laminin receptor activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006407	rRNA export from nucleus	1.11e-03	1.00e+00	9.816	1	1	2
GO:0030529	ribonucleoprotein complex	1.62e-03	1.00e+00	5.009	2	8	112
GO:1900126	negative regulation of hyaluronan biosynthetic process	1.66e-03	1.00e+00	9.231	1	2	3
GO:0071439	clathrin complex	1.66e-03	1.00e+00	9.231	1	2	3
GO:0005654	nucleoplasm	1.73e-03	1.00e+00	2.737	4	76	1082
GO:0006325	chromatin organization	1.80e-03	1.00e+00	4.933	2	5	118
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.22e-03	1.00e+00	8.816	1	1	4
GO:0030686	90S preribosome	2.22e-03	1.00e+00	8.816	1	1	4
GO:0032051	clathrin light chain binding	2.22e-03	1.00e+00	8.816	1	1	4
GO:1903077	negative regulation of protein localization to plasma membrane	2.22e-03	1.00e+00	8.816	1	1	4
GO:0061024	membrane organization	2.70e-03	1.00e+00	4.636	2	7	145
GO:0043248	proteasome assembly	2.77e-03	1.00e+00	8.494	1	1	5
GO:0006102	isocitrate metabolic process	2.77e-03	1.00e+00	8.494	1	1	5
GO:0035925	mRNA 3'-UTR AU-rich region binding	2.77e-03	1.00e+00	8.494	1	1	5
GO:0030130	clathrin coat of trans-Golgi network vesicle	3.32e-03	1.00e+00	8.231	1	3	6
GO:0030957	Tat protein binding	3.32e-03	1.00e+00	8.231	1	3	6
GO:0006101	citrate metabolic process	3.32e-03	1.00e+00	8.231	1	1	6
GO:0030118	clathrin coat	3.32e-03	1.00e+00	8.231	1	2	6
GO:0030132	clathrin coat of coated pit	3.88e-03	1.00e+00	8.009	1	2	7
GO:0000028	ribosomal small subunit assembly	3.88e-03	1.00e+00	8.009	1	1	7
GO:0070688	MLL5-L complex	4.43e-03	1.00e+00	7.816	1	1	8
GO:0000812	Swr1 complex	4.43e-03	1.00e+00	7.816	1	3	8
GO:0010467	gene expression	4.67e-03	1.00e+00	3.015	3	59	669
GO:0070063	RNA polymerase binding	4.98e-03	1.00e+00	7.646	1	1	9
GO:0005829	cytosol	5.45e-03	1.00e+00	1.853	5	132	2496
GO:2000036	regulation of stem cell maintenance	6.09e-03	1.00e+00	7.357	1	1	11
GO:0007067	mitotic nuclear division	6.49e-03	1.00e+00	3.990	2	14	227
GO:0048255	mRNA stabilization	6.64e-03	1.00e+00	7.231	1	2	12
GO:0070935	3'-UTR-mediated mRNA stabilization	6.64e-03	1.00e+00	7.231	1	2	12
GO:0043968	histone H2A acetylation	6.64e-03	1.00e+00	7.231	1	3	12
GO:0005838	proteasome regulatory particle	6.64e-03	1.00e+00	7.231	1	7	12
GO:0021591	ventricular system development	7.19e-03	1.00e+00	7.116	1	2	13
GO:0046827	positive regulation of protein export from nucleus	7.19e-03	1.00e+00	7.116	1	3	13
GO:0017091	AU-rich element binding	7.74e-03	1.00e+00	7.009	1	1	14
GO:0031011	Ino80 complex	7.74e-03	1.00e+00	7.009	1	3	14
GO:0050998	nitric-oxide synthase binding	8.84e-03	1.00e+00	6.816	1	1	16
GO:0003678	DNA helicase activity	9.39e-03	1.00e+00	6.729	1	3	17
GO:0022624	proteasome accessory complex	9.39e-03	1.00e+00	6.729	1	8	17
GO:0048863	stem cell differentiation	1.05e-02	1.00e+00	6.568	1	1	19
GO:0043234	protein complex	1.08e-02	1.00e+00	3.612	2	18	295
GO:0045596	negative regulation of cell differentiation	1.10e-02	1.00e+00	6.494	1	1	20
GO:0030863	cortical cytoskeleton	1.21e-02	1.00e+00	6.357	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.357	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.27e-02	1.00e+00	6.293	1	4	23
GO:0043236	laminin binding	1.27e-02	1.00e+00	6.293	1	1	23
GO:0001944	vasculature development	1.32e-02	1.00e+00	6.231	1	1	24
GO:0034080	CENP-A containing nucleosome assembly	1.38e-02	1.00e+00	6.172	1	1	25
GO:0003730	mRNA 3'-UTR binding	1.43e-02	1.00e+00	6.116	1	2	26
GO:0043022	ribosome binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0071339	MLL1 complex	1.49e-02	1.00e+00	6.061	1	3	27
GO:0043967	histone H4 acetylation	1.49e-02	1.00e+00	6.061	1	3	27
GO:0031492	nucleosomal DNA binding	1.49e-02	1.00e+00	6.061	1	4	27
GO:0005634	nucleus	1.49e-02	1.00e+00	1.247	6	136	4559
GO:0006099	tricarboxylic acid cycle	1.54e-02	1.00e+00	6.009	1	4	28
GO:0030669	clathrin-coated endocytic vesicle membrane	1.54e-02	1.00e+00	6.009	1	4	28
GO:0019894	kinesin binding	1.54e-02	1.00e+00	6.009	1	1	28
GO:0005925	focal adhesion	1.63e-02	1.00e+00	3.300	2	19	366
GO:0033572	transferrin transport	1.65e-02	1.00e+00	5.909	1	5	30
GO:0044822	poly(A) RNA binding	1.66e-02	1.00e+00	2.357	3	49	1056
GO:0031623	receptor internalization	1.71e-02	1.00e+00	5.862	1	2	31
GO:0032588	trans-Golgi network membrane	1.87e-02	1.00e+00	5.729	1	2	34
GO:0001895	retina homeostasis	1.87e-02	1.00e+00	5.729	1	1	34
GO:0051539	4 iron, 4 sulfur cluster binding	1.93e-02	1.00e+00	5.687	1	3	35
GO:0034332	adherens junction organization	1.98e-02	1.00e+00	5.646	1	1	36
GO:0051084	'de novo' posttranslational protein folding	2.03e-02	1.00e+00	5.607	1	4	37
GO:0048839	inner ear development	2.03e-02	1.00e+00	5.607	1	2	37
GO:0070527	platelet aggregation	2.09e-02	1.00e+00	5.568	1	2	38
GO:0022627	cytosolic small ribosomal subunit	2.14e-02	1.00e+00	5.531	1	4	39
GO:0032508	DNA duplex unwinding	2.25e-02	1.00e+00	5.459	1	3	41
GO:0030136	clathrin-coated vesicle	2.31e-02	1.00e+00	5.424	1	4	42
GO:0006892	post-Golgi vesicle-mediated transport	2.36e-02	1.00e+00	5.390	1	3	43
GO:0021762	substantia nigra development	2.42e-02	1.00e+00	5.357	1	2	44
GO:0045727	positive regulation of translation	2.42e-02	1.00e+00	5.357	1	3	44
GO:0044267	cellular protein metabolic process	2.65e-02	1.00e+00	2.927	2	29	474
GO:0006091	generation of precursor metabolites and energy	2.74e-02	1.00e+00	5.172	1	3	50
GO:0006521	regulation of cellular amino acid metabolic process	2.74e-02	1.00e+00	5.172	1	17	50
GO:0040008	regulation of growth	2.74e-02	1.00e+00	5.172	1	5	50
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.90e-02	1.00e+00	5.088	1	5	53
GO:0045216	cell-cell junction organization	2.96e-02	1.00e+00	5.061	1	2	54
GO:0000502	proteasome complex	3.17e-02	1.00e+00	4.958	1	17	58
GO:0005737	cytoplasm	3.28e-02	1.00e+00	1.259	5	110	3767
GO:0016032	viral process	3.30e-02	1.00e+00	2.755	2	55	534
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	3.50e-02	1.00e+00	4.816	1	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.55e-02	1.00e+00	4.794	1	22	65
GO:0006310	DNA recombination	3.55e-02	1.00e+00	4.794	1	2	65
GO:0034329	cell junction assembly	3.71e-02	1.00e+00	4.729	1	1	68
GO:0042393	histone binding	3.76e-02	1.00e+00	4.708	1	1	69
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.82e-02	1.00e+00	4.687	1	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.93e-02	1.00e+00	4.646	1	20	72
GO:0060021	palate development	3.93e-02	1.00e+00	4.646	1	1	72
GO:0003729	mRNA binding	3.93e-02	1.00e+00	4.646	1	3	72
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.03e-02	1.00e+00	4.607	1	6	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.03e-02	1.00e+00	4.607	1	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.09e-02	1.00e+00	4.587	1	20	75
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	4.19e-02	1.00e+00	4.549	1	7	77
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.30e-02	1.00e+00	4.512	1	23	79
GO:0019083	viral transcription	4.41e-02	1.00e+00	4.476	1	10	81
GO:0006898	receptor-mediated endocytosis	4.57e-02	1.00e+00	4.424	1	3	84
GO:0006415	translational termination	4.73e-02	1.00e+00	4.373	1	10	87
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	4.89e-02	1.00e+00	4.324	1	7	90
GO:0042470	melanosome	4.94e-02	1.00e+00	4.308	1	9	91
GO:0016363	nuclear matrix	4.94e-02	1.00e+00	4.308	1	12	91
GO:0006928	cellular component movement	4.94e-02	1.00e+00	4.308	1	7	91
GO:0005200	structural constituent of cytoskeleton	4.94e-02	1.00e+00	4.308	1	8	91
GO:0001649	osteoblast differentiation	4.99e-02	1.00e+00	4.293	1	6	92
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	4.99e-02	1.00e+00	4.293	1	21	92
GO:0006414	translational elongation	5.04e-02	1.00e+00	4.277	1	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.63e-02	1.00e+00	4.116	1	10	104
GO:0014069	postsynaptic density	5.68e-02	1.00e+00	4.102	1	3	105
GO:0005506	iron ion binding	5.68e-02	1.00e+00	4.102	1	4	105
GO:0005815	microtubule organizing center	5.89e-02	1.00e+00	4.048	1	5	109
GO:0072562	blood microparticle	5.99e-02	1.00e+00	4.022	1	3	111
GO:0005819	spindle	6.05e-02	1.00e+00	4.009	1	7	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.15e-02	1.00e+00	3.983	1	11	114
GO:0005515	protein binding	6.16e-02	1.00e+00	0.845	6	184	6024
GO:0019058	viral life cycle	6.20e-02	1.00e+00	3.971	1	13	115
GO:0000209	protein polyubiquitination	6.26e-02	1.00e+00	3.958	1	20	116
GO:0044237	cellular metabolic process	6.31e-02	1.00e+00	3.946	1	5	117
GO:0006511	ubiquitin-dependent protein catabolic process	6.78e-02	1.00e+00	3.839	1	5	126
GO:0000790	nuclear chromatin	6.94e-02	1.00e+00	3.805	1	9	129
GO:0006413	translational initiation	7.04e-02	1.00e+00	3.783	1	17	131
GO:0031982	vesicle	7.04e-02	1.00e+00	3.783	1	9	131
GO:0003735	structural constituent of ribosome	7.35e-02	1.00e+00	3.718	1	10	137
GO:0016887	ATPase activity	7.51e-02	1.00e+00	3.687	1	7	140
GO:0006457	protein folding	7.66e-02	1.00e+00	3.656	1	7	143
GO:0000082	G1/S transition of mitotic cell cycle	7.97e-02	1.00e+00	3.597	1	32	149
GO:0005198	structural molecule activity	8.03e-02	1.00e+00	3.587	1	5	150
GO:0042981	regulation of apoptotic process	8.03e-02	1.00e+00	3.587	1	24	150
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.80e-02	1.00e+00	3.450	1	7	165
GO:0030424	axon	8.85e-02	1.00e+00	3.441	1	4	166
GO:0006886	intracellular protein transport	9.10e-02	1.00e+00	3.398	1	5	171
GO:0034641	cellular nitrogen compound metabolic process	9.10e-02	1.00e+00	3.398	1	20	171
GO:0005759	mitochondrial matrix	1.20e-01	1.00e+00	2.983	1	14	228
GO:0006412	translation	1.21e-01	1.00e+00	2.971	1	20	230
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.799	1	5	259
GO:0007283	spermatogenesis	1.36e-01	1.00e+00	2.783	1	8	262
GO:0006281	DNA repair	1.36e-01	1.00e+00	2.788	1	18	261
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.37e-01	1.00e+00	2.772	1	8	264
GO:0044281	small molecule metabolic process	1.41e-01	1.00e+00	1.574	2	58	1211
GO:0005856	cytoskeleton	1.50e-01	1.00e+00	2.631	1	12	291
GO:0005524	ATP binding	1.58e-01	1.00e+00	1.474	2	60	1298
GO:0007275	multicellular organismal development	1.62e-01	1.00e+00	2.512	1	5	316
GO:0043231	intracellular membrane-bounded organelle	1.63e-01	1.00e+00	2.503	1	9	318
GO:0007411	axon guidance	1.64e-01	1.00e+00	2.499	1	13	319
GO:0003723	RNA binding	1.75e-01	1.00e+00	2.398	1	20	342
GO:0007155	cell adhesion	1.87e-01	1.00e+00	2.289	1	6	369
GO:0000278	mitotic cell cycle	1.97e-01	1.00e+00	2.205	1	48	391
GO:0043066	negative regulation of apoptotic process	2.12e-01	1.00e+00	2.088	1	31	424
GO:0007596	blood coagulation	2.26e-01	1.00e+00	1.986	1	18	455
GO:0005730	nucleolus	2.29e-01	1.00e+00	1.136	2	69	1641
GO:0006915	apoptotic process	2.69e-01	1.00e+00	1.700	1	33	555
GO:0045087	innate immune response	2.87e-01	1.00e+00	1.597	1	24	596
GO:0005794	Golgi apparatus	2.92e-01	1.00e+00	1.563	1	15	610
GO:0005615	extracellular space	4.23e-01	1.00e+00	0.914	1	17	957
GO:0005886	plasma membrane	4.34e-01	1.00e+00	0.482	2	45	2582
GO:0005739	mitochondrion	4.37e-01	1.00e+00	0.853	1	28	998
GO:0006351	transcription, DNA-templated	5.71e-01	1.00e+00	0.318	1	31	1446

Wolf-ratios-Mammosphere-Adherent

int-snw-1994

Statistics

Genes (8)

Interactions (11)

Related GO terms (169)