Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.946 | 6.29e-16 | 1.96e-03 | 3.38e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PPP2R1A | 5518 | 9 | 0.644 | 0.985 | 249 | Yes | - |
RPS11 | 6205 | 36 | 0.993 | 1.113 | 175 | Yes | - |
RPL14 | 9045 | 42 | 1.250 | 1.113 | 143 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
EIF4A1 | 1973 | 3 | 0.866 | 0.981 | 71 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
[ DVL3 ] | 1857 | 1 | -0.026 | 0.946 | 146 | - | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
KPNB1 | 3837 | 6 | 0.613 | 1.017 | 296 | Yes | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PGD | 5226 | PPP2R1A | 5518 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
DVL3 | 1857 | PPP2R1A | 5518 | pp | -- | int.I2D: Jorgensen_EphR |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
EIF4A1 | 1973 | PPP2R1A | 5518 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct |
KPNB1 | 3837 | PSMA2 | 5683 | pp | -- | int.I2D: Krogan_NonCore, YeastLow |
ACO2 | 50 | KPNB1 | 3837 | pp | -- | int.I2D: IntAct_Yeast |
ACTB | 60 | KPNB1 | 3837 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
DVL3 | 1857 | KPNB1 | 3837 | pp | -- | int.I2D: Jorgensen_EphR |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
PPP2R1A | 5518 | PSMA1 | 5682 | pp | -- | int.I2D: IntAct_Mouse |
KPNB1 | 3837 | PSMD11 | 5717 | pp | -- | int.I2D: Krogan_NonCore |
KPNB1 | 3837 | PSMA1 | 5682 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | PPP2R1A | 5518 | pp | -- | int.I2D: BioGrid_Yeast |
PPP2R1A | 5518 | PSMA2 | 5683 | pp | -- | int.I2D: IntAct_Mouse |
RPSA | 3921 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PPP2R1A | 5518 | PSMB7 | 5695 | pp | -- | int.I2D: IntAct_Mouse |
DVL3 | 1857 | EIF4A1 | 1973 | pp | -- | int.I2D: Jorgensen_EphR |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
DVL3 | 1857 | RPS11 | 6205 | pp | -- | int.I2D: Jorgensen_EphR |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0016071 | mRNA metabolic process | 8.05e-14 | 1.16e-09 | 5.378 | 9 | 31 | 223 |
GO:0016070 | RNA metabolic process | 2.04e-13 | 2.94e-09 | 5.230 | 9 | 32 | 247 |
GO:0016032 | viral process | 2.08e-10 | 2.99e-06 | 4.118 | 9 | 55 | 534 |
GO:0010467 | gene expression | 1.53e-09 | 2.21e-05 | 3.793 | 9 | 59 | 669 |
GO:0070062 | extracellular vesicular exosome | 2.88e-08 | 4.15e-04 | 2.365 | 12 | 104 | 2400 |
GO:0005829 | cytosol | 4.54e-08 | 6.55e-04 | 2.308 | 12 | 132 | 2496 |
GO:0006521 | regulation of cellular amino acid metabolic process | 1.25e-07 | 1.80e-03 | 6.365 | 4 | 17 | 50 |
GO:0000502 | proteasome complex | 2.29e-07 | 3.30e-03 | 6.151 | 4 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 3.41e-07 | 4.92e-03 | 6.009 | 4 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.63e-07 | 5.24e-03 | 5.986 | 4 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.91e-07 | 7.08e-03 | 5.879 | 4 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 5.50e-07 | 7.94e-03 | 5.839 | 4 | 20 | 72 |
GO:0005839 | proteasome core complex | 5.89e-07 | 8.50e-03 | 7.424 | 3 | 8 | 18 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.15e-07 | 8.87e-03 | 5.799 | 4 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 6.49e-07 | 9.36e-03 | 5.780 | 4 | 20 | 75 |
GO:0004298 | threonine-type endopeptidase activity | 6.99e-07 | 1.01e-02 | 7.346 | 3 | 8 | 19 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 8.00e-07 | 1.15e-02 | 5.705 | 4 | 23 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.48e-06 | 2.13e-02 | 5.485 | 4 | 21 | 92 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 3.49e-06 | 5.03e-02 | 5.176 | 4 | 11 | 114 |
GO:0019058 | viral life cycle | 3.61e-06 | 5.21e-02 | 5.163 | 4 | 13 | 115 |
GO:0000209 | protein polyubiquitination | 3.74e-06 | 5.39e-02 | 5.151 | 4 | 20 | 116 |
GO:0006413 | translational initiation | 6.06e-06 | 8.75e-02 | 4.975 | 4 | 17 | 131 |
GO:0006915 | apoptotic process | 7.29e-06 | 1.05e-01 | 3.477 | 6 | 33 | 555 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.01e-05 | 1.46e-01 | 4.790 | 4 | 32 | 149 |
GO:0042981 | regulation of apoptotic process | 1.04e-05 | 1.50e-01 | 4.780 | 4 | 24 | 150 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.74e-05 | 2.51e-01 | 4.591 | 4 | 20 | 171 |
GO:0000278 | mitotic cell cycle | 2.33e-05 | 3.37e-01 | 3.720 | 5 | 48 | 391 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 2.44e-05 | 3.52e-01 | 8.009 | 2 | 4 | 8 |
GO:0016020 | membrane | 5.26e-05 | 7.58e-01 | 2.294 | 8 | 90 | 1681 |
GO:0006412 | translation | 5.56e-05 | 8.02e-01 | 4.163 | 4 | 20 | 230 |
GO:0044281 | small molecule metabolic process | 5.85e-05 | 8.44e-01 | 2.574 | 7 | 58 | 1211 |
GO:0044267 | cellular protein metabolic process | 5.88e-05 | 8.48e-01 | 3.442 | 5 | 29 | 474 |
GO:0019083 | viral transcription | 5.94e-05 | 8.57e-01 | 5.254 | 3 | 10 | 81 |
GO:0006415 | translational termination | 7.35e-05 | 1.00e+00 | 5.151 | 3 | 10 | 87 |
GO:0006414 | translational elongation | 8.97e-05 | 1.00e+00 | 5.055 | 3 | 13 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.25e-04 | 1.00e+00 | 4.893 | 3 | 10 | 104 |
GO:0003735 | structural constituent of ribosome | 2.83e-04 | 1.00e+00 | 4.496 | 3 | 10 | 137 |
GO:0005654 | nucleoplasm | 3.12e-04 | 1.00e+00 | 2.514 | 6 | 76 | 1082 |
GO:0043066 | negative regulation of apoptotic process | 5.83e-04 | 1.00e+00 | 3.281 | 4 | 31 | 424 |
GO:0022627 | cytosolic small ribosomal subunit | 6.35e-04 | 1.00e+00 | 5.723 | 2 | 4 | 39 |
GO:0005515 | protein binding | 9.66e-04 | 1.00e+00 | 1.037 | 12 | 184 | 6024 |
GO:0070262 | peptidyl-serine dephosphorylation | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0019521 | D-gluconate metabolic process | 9.71e-04 | 1.00e+00 | 10.009 | 1 | 1 | 1 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 2 | 2 |
GO:0003994 | aconitate hydratase activity | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.94e-03 | 1.00e+00 | 9.009 | 1 | 1 | 2 |
GO:0044822 | poly(A) RNA binding | 2.39e-03 | 1.00e+00 | 2.286 | 5 | 49 | 1056 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 2 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 2.91e-03 | 1.00e+00 | 8.424 | 1 | 1 | 3 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0006610 | ribosomal protein import into nucleus | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0071782 | endoplasmic reticulum tubular network | 3.88e-03 | 1.00e+00 | 8.009 | 1 | 1 | 4 |
GO:0019932 | second-messenger-mediated signaling | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0035567 | non-canonical Wnt signaling pathway | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0060026 | convergent extension | 4.84e-03 | 1.00e+00 | 7.687 | 1 | 1 | 5 |
GO:0015630 | microtubule cytoskeleton | 4.94e-03 | 1.00e+00 | 4.227 | 2 | 4 | 110 |
GO:0030957 | Tat protein binding | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 3 | 6 |
GO:0006101 | citrate metabolic process | 5.81e-03 | 1.00e+00 | 7.424 | 1 | 1 | 6 |
GO:0000028 | ribosomal small subunit assembly | 6.78e-03 | 1.00e+00 | 7.201 | 1 | 1 | 7 |
GO:0000339 | RNA cap binding | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 7.74e-03 | 1.00e+00 | 7.009 | 1 | 1 | 8 |
GO:0008139 | nuclear localization sequence binding | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 3 | 9 |
GO:0016281 | eukaryotic translation initiation factor 4F complex | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 2 | 9 |
GO:0006098 | pentose-phosphate shunt | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 4 | 10 |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 2 | 10 |
GO:0007084 | mitotic nuclear envelope reassembly | 9.67e-03 | 1.00e+00 | 6.687 | 1 | 1 | 10 |
GO:0006275 | regulation of DNA replication | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 2 | 12 |
GO:0030111 | regulation of Wnt signaling pathway | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 1 | 12 |
GO:0005838 | proteasome regulatory particle | 1.16e-02 | 1.00e+00 | 6.424 | 1 | 7 | 12 |
GO:0005634 | nucleus | 1.20e-02 | 1.00e+00 | 1.024 | 9 | 136 | 4559 |
GO:0006672 | ceramide metabolic process | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0042273 | ribosomal large subunit biogenesis | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 4 | 13 |
GO:0090179 | planar cell polarity pathway involved in neural tube closure | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 4 | 14 |
GO:0003148 | outflow tract septum morphogenesis | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 1 | 14 |
GO:0006607 | NLS-bearing protein import into nucleus | 1.35e-02 | 1.00e+00 | 6.201 | 1 | 3 | 14 |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 2 | 15 |
GO:0050998 | nitric-oxide synthase binding | 1.54e-02 | 1.00e+00 | 6.009 | 1 | 1 | 16 |
GO:0075733 | intracellular transport of virus | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 3 | 17 |
GO:0006309 | apoptotic DNA fragmentation | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 1 | 17 |
GO:0022624 | proteasome accessory complex | 1.64e-02 | 1.00e+00 | 5.921 | 1 | 8 | 17 |
GO:0048863 | stem cell differentiation | 1.83e-02 | 1.00e+00 | 5.761 | 1 | 1 | 19 |
GO:0019221 | cytokine-mediated signaling pathway | 1.88e-02 | 1.00e+00 | 3.221 | 2 | 9 | 221 |
GO:0008601 | protein phosphatase type 2A regulator activity | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 2 | 20 |
GO:0090103 | cochlea morphogenesis | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 2 | 20 |
GO:0000159 | protein phosphatase type 2A complex | 1.92e-02 | 1.00e+00 | 5.687 | 1 | 2 | 20 |
GO:0045595 | regulation of cell differentiation | 2.02e-02 | 1.00e+00 | 5.616 | 1 | 1 | 21 |
GO:0003823 | antigen binding | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 1 | 22 |
GO:0030863 | cortical cytoskeleton | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.12e-02 | 1.00e+00 | 5.549 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.21e-02 | 1.00e+00 | 5.485 | 1 | 4 | 23 |
GO:0005844 | polysome | 2.21e-02 | 1.00e+00 | 5.485 | 1 | 4 | 23 |
GO:0043236 | laminin binding | 2.21e-02 | 1.00e+00 | 5.485 | 1 | 1 | 23 |
GO:0008135 | translation factor activity, nucleic acid binding | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 7 | 24 |
GO:0000060 | protein import into nucleus, translocation | 2.31e-02 | 1.00e+00 | 5.424 | 1 | 5 | 24 |
GO:0008536 | Ran GTPase binding | 2.40e-02 | 1.00e+00 | 5.365 | 1 | 1 | 25 |
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | 2.40e-02 | 1.00e+00 | 5.365 | 1 | 1 | 25 |
GO:0010033 | response to organic substance | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 2 | 27 |
GO:0019843 | rRNA binding | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 3 | 27 |
GO:0043022 | ribosome binding | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 3 | 27 |
GO:0050661 | NADP binding | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 2 | 27 |
GO:0000188 | inactivation of MAPK activity | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 1 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.59e-02 | 1.00e+00 | 5.254 | 1 | 4 | 27 |
GO:0006099 | tricarboxylic acid cycle | 2.69e-02 | 1.00e+00 | 5.201 | 1 | 4 | 28 |
GO:0043507 | positive regulation of JUN kinase activity | 2.69e-02 | 1.00e+00 | 5.201 | 1 | 2 | 28 |
GO:0019894 | kinesin binding | 2.69e-02 | 1.00e+00 | 5.201 | 1 | 1 | 28 |
GO:0006606 | protein import into nucleus | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 2 | 30 |
GO:0005109 | frizzled binding | 2.97e-02 | 1.00e+00 | 5.055 | 1 | 1 | 31 |
GO:0001895 | retina homeostasis | 3.25e-02 | 1.00e+00 | 4.921 | 1 | 1 | 34 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.35e-02 | 1.00e+00 | 4.879 | 1 | 3 | 35 |
GO:0034332 | adherens junction organization | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.53e-02 | 1.00e+00 | 4.799 | 1 | 4 | 37 |
GO:0070527 | platelet aggregation | 3.63e-02 | 1.00e+00 | 4.761 | 1 | 2 | 38 |
GO:0008026 | ATP-dependent helicase activity | 3.72e-02 | 1.00e+00 | 4.723 | 1 | 3 | 39 |
GO:0004722 | protein serine/threonine phosphatase activity | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 1 | 42 |
GO:0030155 | regulation of cell adhesion | 4.00e-02 | 1.00e+00 | 4.616 | 1 | 2 | 42 |
GO:0021762 | substantia nigra development | 4.19e-02 | 1.00e+00 | 4.549 | 1 | 2 | 44 |
GO:0003723 | RNA binding | 4.23e-02 | 1.00e+00 | 2.591 | 2 | 20 | 342 |
GO:0006921 | cellular component disassembly involved in execution phase of apoptosis | 4.47e-02 | 1.00e+00 | 4.454 | 1 | 5 | 47 |
GO:0022625 | cytosolic large ribosomal subunit | 4.65e-02 | 1.00e+00 | 4.394 | 1 | 6 | 49 |
GO:0003743 | translation initiation factor activity | 4.65e-02 | 1.00e+00 | 4.394 | 1 | 8 | 49 |
GO:0006091 | generation of precursor metabolites and energy | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 3 | 50 |
GO:0000775 | chromosome, centromeric region | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 2 | 50 |
GO:0031100 | organ regeneration | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 4 | 50 |
GO:0040008 | regulation of growth | 4.75e-02 | 1.00e+00 | 4.365 | 1 | 5 | 50 |
GO:0005925 | focal adhesion | 4.78e-02 | 1.00e+00 | 2.493 | 2 | 19 | 366 |
GO:0003725 | double-stranded RNA binding | 4.93e-02 | 1.00e+00 | 4.308 | 1 | 5 | 52 |
GO:0004386 | helicase activity | 4.93e-02 | 1.00e+00 | 4.308 | 1 | 2 | 52 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 5.03e-02 | 1.00e+00 | 4.281 | 1 | 5 | 53 |
GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 5.03e-02 | 1.00e+00 | 4.281 | 1 | 1 | 53 |
GO:0046982 | protein heterodimerization activity | 5.11e-02 | 1.00e+00 | 2.439 | 2 | 13 | 380 |
GO:0045216 | cell-cell junction organization | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 5.12e-02 | 1.00e+00 | 4.254 | 1 | 3 | 54 |
GO:0008565 | protein transporter activity | 5.30e-02 | 1.00e+00 | 4.201 | 1 | 5 | 56 |
GO:0005643 | nuclear pore | 5.40e-02 | 1.00e+00 | 4.176 | 1 | 4 | 57 |
GO:0005840 | ribosome | 5.49e-02 | 1.00e+00 | 4.151 | 1 | 1 | 58 |
GO:0008013 | beta-catenin binding | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 3 | 60 |
GO:0007059 | chromosome segregation | 5.86e-02 | 1.00e+00 | 4.055 | 1 | 4 | 62 |
GO:0034329 | cell junction assembly | 6.40e-02 | 1.00e+00 | 3.921 | 1 | 1 | 68 |
GO:0003729 | mRNA binding | 6.77e-02 | 1.00e+00 | 3.839 | 1 | 3 | 72 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 6.95e-02 | 1.00e+00 | 3.799 | 1 | 6 | 74 |
GO:0002020 | protease binding | 6.95e-02 | 1.00e+00 | 3.799 | 1 | 4 | 74 |
GO:0060070 | canonical Wnt signaling pathway | 7.04e-02 | 1.00e+00 | 3.780 | 1 | 3 | 75 |
GO:0006928 | cellular component movement | 8.48e-02 | 1.00e+00 | 3.501 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 8.48e-02 | 1.00e+00 | 3.501 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 6 | 92 |
GO:0006364 | rRNA processing | 8.75e-02 | 1.00e+00 | 3.454 | 1 | 6 | 94 |
GO:0006470 | protein dephosphorylation | 9.11e-02 | 1.00e+00 | 3.394 | 1 | 1 | 98 |
GO:0005938 | cell cortex | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 3 | 104 |
GO:0001934 | positive regulation of protein phosphorylation | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 6 | 104 |
GO:0014069 | postsynaptic density | 9.73e-02 | 1.00e+00 | 3.294 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 9.73e-02 | 1.00e+00 | 3.294 | 1 | 4 | 105 |
GO:0030308 | negative regulation of cell growth | 1.02e-01 | 1.00e+00 | 3.227 | 1 | 6 | 110 |
GO:0030529 | ribonucleoprotein complex | 1.03e-01 | 1.00e+00 | 3.201 | 1 | 8 | 112 |
GO:0006461 | protein complex assembly | 1.03e-01 | 1.00e+00 | 3.214 | 1 | 6 | 111 |
GO:0072562 | blood microparticle | 1.03e-01 | 1.00e+00 | 3.214 | 1 | 3 | 111 |
GO:0005635 | nuclear envelope | 1.04e-01 | 1.00e+00 | 3.189 | 1 | 6 | 113 |
GO:0044237 | cellular metabolic process | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 5 | 117 |
GO:0006325 | chromatin organization | 1.09e-01 | 1.00e+00 | 3.126 | 1 | 5 | 118 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.16e-01 | 1.00e+00 | 3.031 | 1 | 5 | 126 |
GO:0009615 | response to virus | 1.16e-01 | 1.00e+00 | 3.031 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.18e-01 | 1.00e+00 | 2.998 | 1 | 9 | 129 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.24e-01 | 1.00e+00 | 2.921 | 1 | 9 | 136 |
GO:0016055 | Wnt signaling pathway | 1.26e-01 | 1.00e+00 | 2.900 | 1 | 7 | 138 |
GO:0006457 | protein folding | 1.30e-01 | 1.00e+00 | 2.849 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.32e-01 | 1.00e+00 | 2.829 | 1 | 7 | 145 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 1.41e-01 | 1.00e+00 | 2.723 | 1 | 9 | 156 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.49e-01 | 1.00e+00 | 2.642 | 1 | 7 | 165 |
GO:0030424 | axon | 1.50e-01 | 1.00e+00 | 2.634 | 1 | 4 | 166 |
GO:0031965 | nuclear membrane | 1.51e-01 | 1.00e+00 | 2.616 | 1 | 3 | 168 |
GO:0019904 | protein domain specific binding | 1.60e-01 | 1.00e+00 | 2.525 | 1 | 6 | 179 |
GO:0008380 | RNA splicing | 2.00e-01 | 1.00e+00 | 2.176 | 1 | 11 | 228 |
GO:0005759 | mitochondrial matrix | 2.00e-01 | 1.00e+00 | 2.176 | 1 | 14 | 228 |
GO:0005730 | nucleolus | 2.08e-01 | 1.00e+00 | 0.913 | 3 | 69 | 1641 |
GO:0005975 | carbohydrate metabolic process | 2.20e-01 | 1.00e+00 | 2.026 | 1 | 9 | 253 |
GO:0005102 | receptor binding | 2.25e-01 | 1.00e+00 | 1.986 | 1 | 6 | 260 |
GO:0019899 | enzyme binding | 2.38e-01 | 1.00e+00 | 1.895 | 1 | 12 | 277 |
GO:0042493 | response to drug | 2.43e-01 | 1.00e+00 | 1.859 | 1 | 13 | 284 |
GO:0005856 | cytoskeleton | 2.48e-01 | 1.00e+00 | 1.824 | 1 | 12 | 291 |
GO:0006200 | ATP catabolic process | 2.49e-01 | 1.00e+00 | 1.819 | 1 | 15 | 292 |
GO:0043234 | protein complex | 2.51e-01 | 1.00e+00 | 1.804 | 1 | 18 | 295 |
GO:0005739 | mitochondrion | 2.52e-01 | 1.00e+00 | 1.046 | 2 | 28 | 998 |
GO:0035556 | intracellular signal transduction | 2.57e-01 | 1.00e+00 | 1.766 | 1 | 9 | 303 |
GO:0019901 | protein kinase binding | 2.67e-01 | 1.00e+00 | 1.700 | 1 | 21 | 317 |
GO:0007411 | axon guidance | 2.69e-01 | 1.00e+00 | 1.691 | 1 | 13 | 319 |
GO:0005813 | centrosome | 2.74e-01 | 1.00e+00 | 1.660 | 1 | 14 | 326 |
GO:0007155 | cell adhesion | 3.04e-01 | 1.00e+00 | 1.481 | 1 | 6 | 369 |
GO:0055114 | oxidation-reduction process | 3.39e-01 | 1.00e+00 | 1.294 | 1 | 12 | 420 |
GO:0007596 | blood coagulation | 3.62e-01 | 1.00e+00 | 1.179 | 1 | 18 | 455 |
GO:0005524 | ATP binding | 3.63e-01 | 1.00e+00 | 0.667 | 2 | 60 | 1298 |
GO:0045893 | positive regulation of transcription, DNA-templated | 3.76e-01 | 1.00e+00 | 1.108 | 1 | 13 | 478 |
GO:0045087 | innate immune response | 4.46e-01 | 1.00e+00 | 0.790 | 1 | 24 | 596 |
GO:0005737 | cytoplasm | 5.18e-01 | 1.00e+00 | 0.130 | 4 | 110 | 3767 |
GO:0005615 | extracellular space | 6.18e-01 | 1.00e+00 | 0.106 | 1 | 17 | 957 |
GO:0006355 | regulation of transcription, DNA-templated | 6.33e-01 | 1.00e+00 | 0.047 | 1 | 18 | 997 |
GO:0008270 | zinc ion binding | 6.33e-01 | 1.00e+00 | 0.047 | 1 | 12 | 997 |
GO:0005886 | plasma membrane | 9.37e-01 | 1.00e+00 | -1.326 | 1 | 45 | 2582 |