int-snw-160

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.924	4.21e-15	3.11e-03	4.72e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-160 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RPS11	6205	36	0.993	1.113	175	Yes	-
[ AP2A1 ]	160	1	-0.151	0.924	73	-	-
RPL14	9045	42	1.250	1.113	143	Yes	-
RPL8	6132	9	0.778	0.967	218	Yes	-
RPL30	6156	4	0.756	1.043	164	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
SAP18	10284	8	1.115	1.069	57	Yes	-
ATP6V1B2	526	44	0.881	1.076	278	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
RPS3A	6189	11	0.835	1.069	166	Yes	-

Interactions (20)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
AP2A1	160	RPL8	6132	pp	--	int.I2D: IntAct_Yeast
RPL30	6156	RPS11	6205	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast
AP2A1	160	RPL30	6156	pp	--	int.I2D: IntAct_Yeast
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2	526	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
ACTB	60	ATP6V1B2	526	pp	--	int.I2D: BioGrid_Yeast
RPL8	6132	RPS3A	6189	pp	--	int.I2D: BioGrid_Yeast
RPS3A	6189	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPL30	6156	RPS3A	6189	pp	--	int.I2D: BioGrid_Yeast
AP2A1	160	RPS3A	6189	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPS3A	6189	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPL30	6156	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
RPL8	6132	RPL30	6156	pp	--	int.I2D: BioGrid_Yeast
RPS3A	6189	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPL8	6132	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
RPS3A	6189	SAP18	10284	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, BioGrid, HPRD, MINT; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid
RPL8	6132	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
AP2A1	160	ATP6V1B2	526	pp	--	int.I2D: IntAct_Yeast

Related GO terms (134)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0019083	viral transcription	5.36e-12	7.73e-08	6.739	6	10	81
GO:0006415	translational termination	8.33e-12	1.20e-07	6.636	6	10	87
GO:0006414	translational elongation	1.26e-11	1.81e-07	6.540	6	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	2.49e-11	3.59e-07	6.379	6	10	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	4.37e-11	6.30e-07	6.246	6	11	114
GO:0019058	viral life cycle	4.61e-11	6.65e-07	6.234	6	13	115
GO:0006413	translational initiation	1.02e-10	1.47e-06	6.046	6	17	131
GO:0003735	structural constituent of ribosome	1.34e-10	1.93e-06	5.981	6	10	137
GO:0016071	mRNA metabolic process	2.55e-09	3.67e-05	5.278	6	31	223
GO:0006412	translation	3.07e-09	4.43e-05	5.234	6	20	230
GO:0044267	cellular protein metabolic process	4.37e-09	6.30e-05	4.413	7	29	474
GO:0016070	RNA metabolic process	4.71e-09	6.79e-05	5.131	6	32	247
GO:0016032	viral process	9.99e-09	1.44e-04	4.241	7	55	534
GO:0044822	poly(A) RNA binding	1.09e-06	1.57e-02	3.257	7	49	1056
GO:0005829	cytosol	1.16e-06	1.68e-02	2.379	9	132	2496
GO:0010467	gene expression	1.74e-06	2.51e-02	3.693	6	59	669
GO:0022627	cytosolic small ribosomal subunit	2.17e-06	3.12e-02	6.794	3	4	39
GO:0005925	focal adhesion	2.32e-06	3.35e-02	4.300	5	19	366
GO:0022625	cytosolic large ribosomal subunit	4.35e-06	6.27e-02	6.464	3	6	49
GO:0016020	membrane	2.52e-05	3.63e-01	2.586	7	90	1681
GO:0003723	RNA binding	5.83e-05	8.40e-01	4.076	4	20	342
GO:0019843	rRNA binding	1.50e-04	1.00e+00	6.739	2	3	27
GO:0070062	extracellular vesicular exosome	2.63e-04	1.00e+00	2.073	7	104	2400
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.39e-03	1.00e+00	9.494	1	1	2
GO:0005055	laminin receptor activity	1.39e-03	1.00e+00	9.494	1	1	2
GO:0006407	rRNA export from nucleus	1.39e-03	1.00e+00	9.494	1	1	2
GO:1900126	negative regulation of hyaluronan biosynthetic process	2.08e-03	1.00e+00	8.909	1	2	3
GO:0061574	ASAP complex	2.08e-03	1.00e+00	8.909	1	1	3
GO:0030529	ribonucleoprotein complex	2.58e-03	1.00e+00	4.687	2	8	112
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.77e-03	1.00e+00	8.494	1	1	4
GO:0030686	90S preribosome	2.77e-03	1.00e+00	8.494	1	1	4
GO:0002181	cytoplasmic translation	4.15e-03	1.00e+00	7.909	1	1	6
GO:0030130	clathrin coat of trans-Golgi network vesicle	4.15e-03	1.00e+00	7.909	1	3	6
GO:0030957	Tat protein binding	4.15e-03	1.00e+00	7.909	1	3	6
GO:0033180	proton-transporting V-type ATPase, V1 domain	4.84e-03	1.00e+00	7.687	1	2	7
GO:0000028	ribosomal small subunit assembly	4.84e-03	1.00e+00	7.687	1	1	7
GO:0035615	clathrin adaptor activity	5.53e-03	1.00e+00	7.494	1	2	8
GO:0070688	MLL5-L complex	5.53e-03	1.00e+00	7.494	1	1	8
GO:0030122	AP-2 adaptor complex	6.91e-03	1.00e+00	7.172	1	2	10
GO:0006895	Golgi to endosome transport	7.60e-03	1.00e+00	7.035	1	1	11
GO:0072583	clathrin-mediated endocytosis	8.29e-03	1.00e+00	6.909	1	2	12
GO:0042273	ribosomal large subunit biogenesis	8.98e-03	1.00e+00	6.794	1	4	13
GO:0035267	NuA4 histone acetyltransferase complex	9.67e-03	1.00e+00	6.687	1	4	14
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1.04e-02	1.00e+00	6.587	1	3	15
GO:0048025	negative regulation of mRNA splicing, via spliceosome	1.04e-02	1.00e+00	6.587	1	1	15
GO:0046034	ATP metabolic process	1.04e-02	1.00e+00	6.587	1	1	15
GO:0050998	nitric-oxide synthase binding	1.10e-02	1.00e+00	6.494	1	1	16
GO:0015078	hydrogen ion transmembrane transporter activity	1.31e-02	1.00e+00	6.246	1	3	19
GO:0035145	exon-exon junction complex	1.31e-02	1.00e+00	6.246	1	1	19
GO:0030863	cortical cytoskeleton	1.52e-02	1.00e+00	6.035	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.52e-02	1.00e+00	6.035	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.58e-02	1.00e+00	5.971	1	4	23
GO:0043236	laminin binding	1.58e-02	1.00e+00	5.971	1	1	23
GO:0005515	protein binding	1.65e-02	1.00e+00	0.938	8	184	6024
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	1.79e-02	1.00e+00	5.794	1	1	26
GO:0015991	ATP hydrolysis coupled proton transport	1.79e-02	1.00e+00	5.794	1	4	26
GO:0050690	regulation of defense response to virus by virus	1.86e-02	1.00e+00	5.739	1	4	27
GO:0043022	ribosome binding	1.86e-02	1.00e+00	5.739	1	3	27
GO:0031492	nucleosomal DNA binding	1.86e-02	1.00e+00	5.739	1	4	27
GO:0019901	protein kinase binding	1.93e-02	1.00e+00	3.186	2	21	317
GO:0030669	clathrin-coated endocytic vesicle membrane	1.93e-02	1.00e+00	5.687	1	4	28
GO:0000118	histone deacetylase complex	1.93e-02	1.00e+00	5.687	1	1	28
GO:0019894	kinesin binding	1.93e-02	1.00e+00	5.687	1	1	28
GO:0007411	axon guidance	1.95e-02	1.00e+00	3.177	2	13	319
GO:0015992	proton transport	1.99e-02	1.00e+00	5.636	1	3	29
GO:0033572	transferrin transport	2.06e-02	1.00e+00	5.587	1	5	30
GO:1903507	negative regulation of nucleic acid-templated transcription	2.20e-02	1.00e+00	5.494	1	2	32
GO:0051701	interaction with host	2.20e-02	1.00e+00	5.494	1	4	32
GO:0001895	retina homeostasis	2.33e-02	1.00e+00	5.407	1	1	34
GO:0005737	cytoplasm	2.44e-02	1.00e+00	1.200	6	110	3767
GO:0034332	adherens junction organization	2.47e-02	1.00e+00	5.324	1	1	36
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	2.47e-02	1.00e+00	5.324	1	4	36
GO:0090382	phagosome maturation	2.47e-02	1.00e+00	5.324	1	5	36
GO:0051084	'de novo' posttranslational protein folding	2.54e-02	1.00e+00	5.285	1	4	37
GO:0005902	microvillus	2.60e-02	1.00e+00	5.246	1	2	38
GO:0070527	platelet aggregation	2.60e-02	1.00e+00	5.246	1	2	38
GO:0021762	substantia nigra development	3.01e-02	1.00e+00	5.035	1	2	44
GO:0006879	cellular iron ion homeostasis	3.48e-02	1.00e+00	4.822	1	4	51
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3.62e-02	1.00e+00	4.766	1	5	53
GO:0030666	endocytic vesicle membrane	3.62e-02	1.00e+00	4.766	1	4	53
GO:0045216	cell-cell junction organization	3.68e-02	1.00e+00	4.739	1	2	54
GO:0008565	protein transporter activity	3.82e-02	1.00e+00	4.687	1	5	56
GO:0012505	endomembrane system	3.82e-02	1.00e+00	4.687	1	2	56
GO:0005840	ribosome	3.95e-02	1.00e+00	4.636	1	1	58
GO:0034329	cell junction assembly	4.62e-02	1.00e+00	4.407	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	5.02e-02	1.00e+00	4.285	1	6	74
GO:0001726	ruffle	5.41e-02	1.00e+00	4.172	1	4	80
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	6.07e-02	1.00e+00	4.002	1	7	90
GO:0042470	melanosome	6.14e-02	1.00e+00	3.986	1	9	91
GO:0006928	cellular component movement	6.14e-02	1.00e+00	3.986	1	7	91
GO:0005200	structural constituent of cytoskeleton	6.14e-02	1.00e+00	3.986	1	8	91
GO:0001649	osteoblast differentiation	6.20e-02	1.00e+00	3.971	1	6	92
GO:0006364	rRNA processing	6.33e-02	1.00e+00	3.940	1	6	94
GO:0014069	postsynaptic density	7.05e-02	1.00e+00	3.780	1	3	105
GO:0006897	endocytosis	7.11e-02	1.00e+00	3.766	1	8	106
GO:0072562	blood microparticle	7.44e-02	1.00e+00	3.700	1	3	111
GO:0006325	chromatin organization	7.89e-02	1.00e+00	3.612	1	5	118
GO:0000790	nuclear chromatin	8.60e-02	1.00e+00	3.483	1	9	129
GO:0016323	basolateral plasma membrane	8.98e-02	1.00e+00	3.417	1	4	135
GO:0008286	insulin receptor signaling pathway	9.42e-02	1.00e+00	3.344	1	7	142
GO:0006457	protein folding	9.49e-02	1.00e+00	3.334	1	7	143
GO:0061024	membrane organization	9.61e-02	1.00e+00	3.314	1	7	145
GO:0006397	mRNA processing	1.06e-01	1.00e+00	3.172	1	2	160
GO:0008022	protein C-terminus binding	1.06e-01	1.00e+00	3.163	1	5	161
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.09e-01	1.00e+00	3.128	1	7	165
GO:0030424	axon	1.09e-01	1.00e+00	3.119	1	4	166
GO:0006886	intracellular protein transport	1.12e-01	1.00e+00	3.076	1	5	171
GO:0016607	nuclear speck	1.13e-01	1.00e+00	3.068	1	3	172
GO:0003714	transcription corepressor activity	1.17e-01	1.00e+00	3.018	1	8	178
GO:0007173	epidermal growth factor receptor signaling pathway	1.24e-01	1.00e+00	2.932	1	12	189
GO:0016324	apical plasma membrane	1.30e-01	1.00e+00	2.858	1	5	199
GO:0005765	lysosomal membrane	1.32e-01	1.00e+00	2.829	1	5	203
GO:0008380	RNA splicing	1.47e-01	1.00e+00	2.661	1	11	228
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.69e-01	1.00e+00	2.450	1	8	264
GO:0043065	positive regulation of apoptotic process	1.71e-01	1.00e+00	2.428	1	10	268
GO:0048011	neurotrophin TRK receptor signaling pathway	1.72e-01	1.00e+00	2.423	1	15	269
GO:0005856	cytoskeleton	1.84e-01	1.00e+00	2.309	1	12	291
GO:0043234	protein complex	1.87e-01	1.00e+00	2.290	1	18	295
GO:0030154	cell differentiation	1.90e-01	1.00e+00	2.261	1	5	301
GO:0043231	intracellular membrane-bounded organelle	2.00e-01	1.00e+00	2.181	1	9	318
GO:0007268	synaptic transmission	2.08e-01	1.00e+00	2.119	1	6	332
GO:0005524	ATP binding	2.25e-01	1.00e+00	1.152	2	60	1298
GO:0007155	cell adhesion	2.28e-01	1.00e+00	1.967	1	6	369
GO:0043066	negative regulation of apoptotic process	2.58e-01	1.00e+00	1.766	1	31	424
GO:0005886	plasma membrane	2.60e-01	1.00e+00	0.745	3	45	2582
GO:0055085	transmembrane transport	2.64e-01	1.00e+00	1.729	1	10	435
GO:0007596	blood coagulation	2.74e-01	1.00e+00	1.664	1	18	455
GO:0005730	nucleolus	3.18e-01	1.00e+00	0.814	2	69	1641
GO:0045087	innate immune response	3.44e-01	1.00e+00	1.275	1	24	596
GO:0005634	nucleus	3.94e-01	1.00e+00	0.340	4	136	4559
GO:0005615	extracellular space	4.97e-01	1.00e+00	0.592	1	17	957
GO:0005654	nucleoplasm	5.42e-01	1.00e+00	0.415	1	76	1082
GO:0006351	transcription, DNA-templated	6.52e-01	1.00e+00	-0.004	1	31	1446
GO:0016021	integral component of membrane	7.72e-01	1.00e+00	-0.459	1	27	1982

Wolf-ratios-Mammosphere-Adherent

int-snw-160

Statistics

Genes (10)

Interactions (20)

Related GO terms (134)