Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.926 | 3.62e-15 | 3.00e-03 | 4.60e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
RPS11 | 6205 | 36 | 0.993 | 1.113 | 175 | Yes | - |
RPL14 | 9045 | 42 | 1.250 | 1.113 | 143 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
RNF2 | 6045 | 2 | 0.423 | 0.926 | 106 | - | - |
[ UBE2E3 ] | 10477 | 1 | 0.274 | 0.926 | 68 | - | - |
UBB | 7314 | 2 | 0.477 | 1.041 | 147 | - | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | UBB | 7314 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RPSA | 3921 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
UBB | 7314 | UBE2E3 | 10477 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
RNF2 | 6045 | UBE2E3 | 10477 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct |
RPS11 | 6205 | RPL14 | 9045 | pp | -- | int.I2D: BioGrid_Yeast |
RPL14 | 9045 | UBE2E3 | 10477 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0019058 | viral life cycle | 4.69e-07 | 6.76e-03 | 5.801 | 4 | 13 | 115 |
GO:0016071 | mRNA metabolic process | 6.60e-06 | 9.51e-02 | 4.845 | 4 | 31 | 223 |
GO:0016032 | viral process | 7.60e-06 | 1.10e-01 | 3.907 | 5 | 55 | 534 |
GO:0016070 | RNA metabolic process | 9.89e-06 | 1.43e-01 | 4.698 | 4 | 32 | 247 |
GO:0019083 | viral transcription | 1.40e-05 | 2.02e-01 | 5.891 | 3 | 10 | 81 |
GO:0006415 | translational termination | 1.73e-05 | 2.50e-01 | 5.788 | 3 | 10 | 87 |
GO:0006414 | translational elongation | 2.12e-05 | 3.06e-01 | 5.692 | 3 | 13 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 2.96e-05 | 4.28e-01 | 5.531 | 3 | 10 | 104 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 3.90e-05 | 5.63e-01 | 5.398 | 3 | 11 | 114 |
GO:0006413 | translational initiation | 5.91e-05 | 8.52e-01 | 5.198 | 3 | 17 | 131 |
GO:0003735 | structural constituent of ribosome | 6.75e-05 | 9.74e-01 | 5.133 | 3 | 10 | 137 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 1.12e-04 | 1.00e+00 | 6.946 | 2 | 3 | 26 |
GO:0044267 | cellular protein metabolic process | 1.27e-04 | 1.00e+00 | 3.757 | 4 | 29 | 474 |
GO:0005654 | nucleoplasm | 2.30e-04 | 1.00e+00 | 2.889 | 5 | 76 | 1082 |
GO:0022627 | cytosolic small ribosomal subunit | 2.53e-04 | 1.00e+00 | 6.361 | 2 | 4 | 39 |
GO:0006412 | translation | 3.13e-04 | 1.00e+00 | 4.386 | 3 | 20 | 230 |
GO:0004842 | ubiquitin-protein transferase activity | 4.24e-04 | 1.00e+00 | 4.237 | 3 | 6 | 255 |
GO:0006281 | DNA repair | 4.54e-04 | 1.00e+00 | 4.203 | 3 | 18 | 261 |
GO:0010467 | gene expression | 4.79e-04 | 1.00e+00 | 3.260 | 4 | 59 | 669 |
GO:0036353 | histone H2A-K119 monoubiquitination | 6.24e-04 | 1.00e+00 | 10.646 | 1 | 1 | 1 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator | 1.25e-03 | 1.00e+00 | 9.646 | 1 | 1 | 2 |
GO:0005829 | cytosol | 1.39e-03 | 1.00e+00 | 1.946 | 6 | 132 | 2496 |
GO:0071456 | cellular response to hypoxia | 1.41e-03 | 1.00e+00 | 5.123 | 2 | 6 | 92 |
GO:0000278 | mitotic cell cycle | 1.47e-03 | 1.00e+00 | 3.620 | 3 | 48 | 391 |
GO:0071535 | RING-like zinc finger domain binding | 1.87e-03 | 1.00e+00 | 9.061 | 1 | 1 | 3 |
GO:0007219 | Notch signaling pathway | 2.38e-03 | 1.00e+00 | 4.739 | 2 | 5 | 120 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 2.49e-03 | 1.00e+00 | 8.646 | 1 | 1 | 4 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 5 |
GO:0061024 | membrane organization | 3.45e-03 | 1.00e+00 | 4.466 | 2 | 7 | 145 |
GO:0000082 | G1/S transition of mitotic cell cycle | 3.64e-03 | 1.00e+00 | 4.427 | 2 | 32 | 149 |
GO:0000791 | euchromatin | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 3 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 3.74e-03 | 1.00e+00 | 8.061 | 1 | 1 | 6 |
GO:0000028 | ribosomal small subunit assembly | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 1 | 7 |
GO:0001739 | sex chromatin | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 4.36e-03 | 1.00e+00 | 7.839 | 1 | 2 | 7 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 8 |
GO:0070688 | MLL5-L complex | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 4.98e-03 | 1.00e+00 | 7.646 | 1 | 2 | 8 |
GO:0031625 | ubiquitin protein ligase binding | 5.15e-03 | 1.00e+00 | 4.170 | 2 | 14 | 178 |
GO:0005515 | protein binding | 5.23e-03 | 1.00e+00 | 1.090 | 8 | 184 | 6024 |
GO:0047497 | mitochondrion transport along microtubule | 5.60e-03 | 1.00e+00 | 7.476 | 1 | 3 | 9 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 10 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 4 | 11 |
GO:0035518 | histone H2A monoubiquitination | 6.85e-03 | 1.00e+00 | 7.187 | 1 | 3 | 11 |
GO:0061136 | regulation of proteasomal protein catabolic process | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 2 | 12 |
GO:0035102 | PRC1 complex | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 12 |
GO:1901214 | regulation of neuron death | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 12 |
GO:0019082 | viral protein processing | 7.47e-03 | 1.00e+00 | 7.061 | 1 | 1 | 12 |
GO:0042273 | ribosomal large subunit biogenesis | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 4 | 13 |
GO:0005662 | DNA replication factor A complex | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 13 |
GO:0032479 | regulation of type I interferon production | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 1 | 13 |
GO:0035267 | NuA4 histone acetyltransferase complex | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 4 | 14 |
GO:0009948 | anterior/posterior axis specification | 8.70e-03 | 1.00e+00 | 6.839 | 1 | 2 | 14 |
GO:0070062 | extracellular vesicular exosome | 8.87e-03 | 1.00e+00 | 1.739 | 5 | 104 | 2400 |
GO:0050998 | nitric-oxide synthase binding | 9.94e-03 | 1.00e+00 | 6.646 | 1 | 1 | 16 |
GO:0075733 | intracellular transport of virus | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 3 | 17 |
GO:0019068 | virion assembly | 1.06e-02 | 1.00e+00 | 6.559 | 1 | 1 | 17 |
GO:0035861 | site of double-strand break | 1.12e-02 | 1.00e+00 | 6.476 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.18e-02 | 1.00e+00 | 6.398 | 1 | 1 | 19 |
GO:0006298 | mismatch repair | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 3 | 20 |
GO:0051881 | regulation of mitochondrial membrane potential | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 2 | 20 |
GO:0032201 | telomere maintenance via semi-conservative replication | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 5 | 21 |
GO:0001702 | gastrulation with mouth forming second | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 2 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.30e-02 | 1.00e+00 | 6.254 | 1 | 4 | 21 |
GO:0007220 | Notch receptor processing | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 22 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.36e-02 | 1.00e+00 | 6.187 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 1 | 23 |
GO:0016020 | membrane | 1.43e-02 | 1.00e+00 | 1.931 | 4 | 90 | 1681 |
GO:0006513 | protein monoubiquitination | 1.43e-02 | 1.00e+00 | 6.123 | 1 | 1 | 23 |
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 3 | 25 |
GO:0000722 | telomere maintenance via recombination | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 5 | 25 |
GO:0031519 | PcG protein complex | 1.55e-02 | 1.00e+00 | 6.002 | 1 | 4 | 25 |
GO:0005978 | glycogen biosynthetic process | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 26 |
GO:0070979 | protein K11-linked ubiquitination | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 6 | 26 |
GO:0019843 | rRNA binding | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 3 | 27 |
GO:0043022 | ribosome binding | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 3 | 27 |
GO:0071339 | MLL1 complex | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 1.67e-02 | 1.00e+00 | 5.891 | 1 | 4 | 27 |
GO:0019894 | kinesin binding | 1.73e-02 | 1.00e+00 | 5.839 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 1.80e-02 | 1.00e+00 | 5.788 | 1 | 1 | 29 |
GO:0006271 | DNA strand elongation involved in DNA replication | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 7 | 30 |
GO:0048812 | neuron projection morphogenesis | 1.92e-02 | 1.00e+00 | 5.692 | 1 | 1 | 31 |
GO:0070534 | protein K63-linked ubiquitination | 1.92e-02 | 1.00e+00 | 5.692 | 1 | 1 | 31 |
GO:0016604 | nuclear body | 1.92e-02 | 1.00e+00 | 5.692 | 1 | 2 | 31 |
GO:0032480 | negative regulation of type I interferon production | 1.98e-02 | 1.00e+00 | 5.646 | 1 | 1 | 32 |
GO:0005925 | focal adhesion | 2.05e-02 | 1.00e+00 | 3.130 | 2 | 19 | 366 |
GO:0001895 | retina homeostasis | 2.10e-02 | 1.00e+00 | 5.559 | 1 | 1 | 34 |
GO:0034332 | adherens junction organization | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 1 | 36 |
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 2.22e-02 | 1.00e+00 | 5.476 | 1 | 4 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 2.29e-02 | 1.00e+00 | 5.437 | 1 | 4 | 37 |
GO:0016881 | acid-amino acid ligase activity | 2.29e-02 | 1.00e+00 | 5.437 | 1 | 2 | 37 |
GO:0006284 | base-excision repair | 2.29e-02 | 1.00e+00 | 5.437 | 1 | 3 | 37 |
GO:0044822 | poly(A) RNA binding | 2.35e-02 | 1.00e+00 | 2.187 | 3 | 49 | 1056 |
GO:0070527 | platelet aggregation | 2.35e-02 | 1.00e+00 | 5.398 | 1 | 2 | 38 |
GO:0000781 | chromosome, telomeric region | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 3 | 39 |
GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 2.53e-02 | 1.00e+00 | 5.289 | 1 | 2 | 41 |
GO:0035872 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | 2.65e-02 | 1.00e+00 | 5.220 | 1 | 4 | 43 |
GO:0021762 | substantia nigra development | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 44 |
GO:0070936 | protein K48-linked ubiquitination | 2.71e-02 | 1.00e+00 | 5.187 | 1 | 2 | 44 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 2.83e-02 | 1.00e+00 | 5.123 | 1 | 7 | 46 |
GO:0022625 | cytosolic large ribosomal subunit | 3.02e-02 | 1.00e+00 | 5.031 | 1 | 6 | 49 |
GO:0007254 | JNK cascade | 3.02e-02 | 1.00e+00 | 5.031 | 1 | 3 | 49 |
GO:0003684 | damaged DNA binding | 3.02e-02 | 1.00e+00 | 5.031 | 1 | 7 | 49 |
GO:0040008 | regulation of growth | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 5 | 50 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 5 | 53 |
GO:0030666 | endocytic vesicle membrane | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 4 | 53 |
GO:0045216 | cell-cell junction organization | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 54 |
GO:0051403 | stress-activated MAPK cascade | 3.32e-02 | 1.00e+00 | 4.891 | 1 | 2 | 54 |
GO:0000724 | double-strand break repair via homologous recombination | 3.38e-02 | 1.00e+00 | 4.865 | 1 | 3 | 55 |
GO:0000723 | telomere maintenance | 3.44e-02 | 1.00e+00 | 4.839 | 1 | 6 | 56 |
GO:0016197 | endosomal transport | 3.50e-02 | 1.00e+00 | 4.813 | 1 | 1 | 57 |
GO:0005840 | ribosome | 3.56e-02 | 1.00e+00 | 4.788 | 1 | 1 | 58 |
GO:0032481 | positive regulation of type I interferon production | 3.74e-02 | 1.00e+00 | 4.715 | 1 | 6 | 61 |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 3.74e-02 | 1.00e+00 | 4.715 | 1 | 2 | 61 |
GO:0019903 | protein phosphatase binding | 3.80e-02 | 1.00e+00 | 4.692 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 3.80e-02 | 1.00e+00 | 4.692 | 1 | 4 | 62 |
GO:0000151 | ubiquitin ligase complex | 3.86e-02 | 1.00e+00 | 4.669 | 1 | 1 | 63 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 3.92e-02 | 1.00e+00 | 4.646 | 1 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 22 | 65 |
GO:0034146 | toll-like receptor 5 signaling pathway | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 2 | 65 |
GO:0034166 | toll-like receptor 10 signaling pathway | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 2 | 65 |
GO:0006289 | nucleotide-excision repair | 4.17e-02 | 1.00e+00 | 4.559 | 1 | 11 | 68 |
GO:0034329 | cell junction assembly | 4.17e-02 | 1.00e+00 | 4.559 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 4.17e-02 | 1.00e+00 | 4.559 | 1 | 5 | 68 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.29e-02 | 1.00e+00 | 4.517 | 1 | 22 | 70 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 4.35e-02 | 1.00e+00 | 4.496 | 1 | 2 | 71 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 4.35e-02 | 1.00e+00 | 4.496 | 1 | 2 | 71 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 4.41e-02 | 1.00e+00 | 4.476 | 1 | 20 | 72 |
GO:0034162 | toll-like receptor 9 signaling pathway | 4.41e-02 | 1.00e+00 | 4.476 | 1 | 2 | 72 |
GO:0034134 | toll-like receptor 2 signaling pathway | 4.47e-02 | 1.00e+00 | 4.456 | 1 | 2 | 73 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 4.53e-02 | 1.00e+00 | 4.437 | 1 | 6 | 74 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.53e-02 | 1.00e+00 | 4.437 | 1 | 22 | 74 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 4.59e-02 | 1.00e+00 | 4.417 | 1 | 2 | 75 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 4.59e-02 | 1.00e+00 | 4.417 | 1 | 20 | 75 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 4.64e-02 | 1.00e+00 | 4.398 | 1 | 3 | 76 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 4.67e-02 | 1.00e+00 | 2.491 | 2 | 16 | 570 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 3 | 78 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 4.82e-02 | 1.00e+00 | 4.342 | 1 | 23 | 79 |
GO:0034138 | toll-like receptor 3 signaling pathway | 4.82e-02 | 1.00e+00 | 4.342 | 1 | 3 | 79 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 4.88e-02 | 1.00e+00 | 4.324 | 1 | 3 | 80 |
GO:0045087 | innate immune response | 5.06e-02 | 1.00e+00 | 2.427 | 2 | 24 | 596 |
GO:0050852 | T cell receptor signaling pathway | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 4 | 85 |
GO:0047485 | protein N-terminus binding | 5.24e-02 | 1.00e+00 | 4.220 | 1 | 5 | 86 |
GO:0016605 | PML body | 5.36e-02 | 1.00e+00 | 4.187 | 1 | 3 | 88 |
GO:0000187 | activation of MAPK activity | 5.48e-02 | 1.00e+00 | 4.154 | 1 | 5 | 90 |
GO:0006928 | cellular component movement | 5.54e-02 | 1.00e+00 | 4.138 | 1 | 7 | 91 |
GO:0005200 | structural constituent of cytoskeleton | 5.54e-02 | 1.00e+00 | 4.138 | 1 | 8 | 91 |
GO:0001649 | osteoblast differentiation | 5.60e-02 | 1.00e+00 | 4.123 | 1 | 6 | 92 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 5.60e-02 | 1.00e+00 | 4.123 | 1 | 21 | 92 |
GO:0006364 | rRNA processing | 5.72e-02 | 1.00e+00 | 4.092 | 1 | 6 | 94 |
GO:0034142 | toll-like receptor 4 signaling pathway | 5.83e-02 | 1.00e+00 | 4.061 | 1 | 3 | 96 |
GO:0014069 | postsynaptic density | 6.37e-02 | 1.00e+00 | 3.932 | 1 | 3 | 105 |
GO:0002224 | toll-like receptor signaling pathway | 6.60e-02 | 1.00e+00 | 3.878 | 1 | 3 | 109 |
GO:0072562 | blood microparticle | 6.72e-02 | 1.00e+00 | 3.852 | 1 | 3 | 111 |
GO:0030529 | ribonucleoprotein complex | 6.78e-02 | 1.00e+00 | 3.839 | 1 | 8 | 112 |
GO:0097190 | apoptotic signaling pathway | 6.84e-02 | 1.00e+00 | 3.826 | 1 | 6 | 113 |
GO:0000209 | protein polyubiquitination | 7.01e-02 | 1.00e+00 | 3.788 | 1 | 20 | 116 |
GO:0006006 | glucose metabolic process | 7.13e-02 | 1.00e+00 | 3.764 | 1 | 7 | 118 |
GO:0006325 | chromatin organization | 7.13e-02 | 1.00e+00 | 3.764 | 1 | 5 | 118 |
GO:0006260 | DNA replication | 7.30e-02 | 1.00e+00 | 3.727 | 1 | 9 | 121 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 7.48e-02 | 1.00e+00 | 3.692 | 1 | 4 | 124 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 7.71e-02 | 1.00e+00 | 3.646 | 1 | 4 | 128 |
GO:0000790 | nuclear chromatin | 7.77e-02 | 1.00e+00 | 3.635 | 1 | 9 | 129 |
GO:0000086 | G2/M transition of mitotic cell cycle | 8.18e-02 | 1.00e+00 | 3.559 | 1 | 9 | 136 |
GO:0006457 | protein folding | 8.58e-02 | 1.00e+00 | 3.486 | 1 | 7 | 143 |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 8.69e-02 | 1.00e+00 | 3.466 | 1 | 4 | 145 |
GO:0034220 | ion transmembrane transport | 8.92e-02 | 1.00e+00 | 3.427 | 1 | 4 | 149 |
GO:0042981 | regulation of apoptotic process | 8.98e-02 | 1.00e+00 | 3.417 | 1 | 24 | 150 |
GO:0010008 | endosome membrane | 9.04e-02 | 1.00e+00 | 3.408 | 1 | 7 | 151 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 9.33e-02 | 1.00e+00 | 3.361 | 1 | 9 | 156 |
GO:0043005 | neuron projection | 9.38e-02 | 1.00e+00 | 3.352 | 1 | 6 | 157 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 9.84e-02 | 1.00e+00 | 3.280 | 1 | 7 | 165 |
GO:0030424 | axon | 9.90e-02 | 1.00e+00 | 3.271 | 1 | 4 | 166 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 1.00e-01 | 1.00e+00 | 3.254 | 1 | 12 | 168 |
GO:0032403 | protein complex binding | 1.09e-01 | 1.00e+00 | 3.130 | 1 | 10 | 183 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 1.09e-01 | 1.00e+00 | 3.123 | 1 | 8 | 184 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 1.12e-01 | 1.00e+00 | 3.084 | 1 | 12 | 189 |
GO:0008270 | zinc ion binding | 1.24e-01 | 1.00e+00 | 1.685 | 2 | 12 | 997 |
GO:0016874 | ligase activity | 1.26e-01 | 1.00e+00 | 2.905 | 1 | 1 | 214 |
GO:0019221 | cytokine-mediated signaling pathway | 1.30e-01 | 1.00e+00 | 2.858 | 1 | 9 | 221 |
GO:0043025 | neuronal cell body | 1.43e-01 | 1.00e+00 | 2.710 | 1 | 9 | 245 |
GO:0005975 | carbohydrate metabolic process | 1.47e-01 | 1.00e+00 | 2.663 | 1 | 9 | 253 |
GO:0043065 | positive regulation of apoptotic process | 1.55e-01 | 1.00e+00 | 2.580 | 1 | 10 | 268 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 1.56e-01 | 1.00e+00 | 2.575 | 1 | 15 | 269 |
GO:0019899 | enzyme binding | 1.60e-01 | 1.00e+00 | 2.532 | 1 | 12 | 277 |
GO:0005856 | cytoskeleton | 1.68e-01 | 1.00e+00 | 2.461 | 1 | 12 | 291 |
GO:0043234 | protein complex | 1.70e-01 | 1.00e+00 | 2.442 | 1 | 18 | 295 |
GO:0016567 | protein ubiquitination | 1.70e-01 | 1.00e+00 | 2.442 | 1 | 5 | 295 |
GO:0019901 | protein kinase binding | 1.81e-01 | 1.00e+00 | 2.338 | 1 | 21 | 317 |
GO:0007411 | axon guidance | 1.82e-01 | 1.00e+00 | 2.329 | 1 | 13 | 319 |
GO:0005737 | cytoplasm | 1.87e-01 | 1.00e+00 | 0.767 | 4 | 110 | 3767 |
GO:0003682 | chromatin binding | 1.87e-01 | 1.00e+00 | 2.293 | 1 | 11 | 327 |
GO:0005524 | ATP binding | 1.91e-01 | 1.00e+00 | 1.304 | 2 | 60 | 1298 |
GO:0003723 | RNA binding | 1.94e-01 | 1.00e+00 | 2.228 | 1 | 20 | 342 |
GO:0007155 | cell adhesion | 2.08e-01 | 1.00e+00 | 2.119 | 1 | 6 | 369 |
GO:0006351 | transcription, DNA-templated | 2.26e-01 | 1.00e+00 | 1.148 | 2 | 31 | 1446 |
GO:0043066 | negative regulation of apoptotic process | 2.36e-01 | 1.00e+00 | 1.918 | 1 | 31 | 424 |
GO:0055085 | transmembrane transport | 2.41e-01 | 1.00e+00 | 1.881 | 1 | 10 | 435 |
GO:0007596 | blood coagulation | 2.51e-01 | 1.00e+00 | 1.816 | 1 | 18 | 455 |
GO:0005730 | nucleolus | 2.73e-01 | 1.00e+00 | 0.966 | 2 | 69 | 1641 |
GO:0006915 | apoptotic process | 2.98e-01 | 1.00e+00 | 1.530 | 1 | 33 | 555 |
GO:0005634 | nucleus | 3.08e-01 | 1.00e+00 | 0.492 | 4 | 136 | 4559 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 3.97e-01 | 1.00e+00 | 1.022 | 1 | 19 | 789 |
GO:0005615 | extracellular space | 4.61e-01 | 1.00e+00 | 0.744 | 1 | 17 | 957 |
GO:0005739 | mitochondrion | 4.76e-01 | 1.00e+00 | 0.683 | 1 | 28 | 998 |
GO:0005886 | plasma membrane | 4.98e-01 | 1.00e+00 | 0.312 | 2 | 45 | 2582 |
GO:0044281 | small molecule metabolic process | 5.46e-01 | 1.00e+00 | 0.404 | 1 | 58 | 1211 |