int-snw-1040

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.960	1.76e-16	1.43e-03	2.69e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-1040 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
ACACB	32	5	0.656	1.002	184	Yes	-
PSMD3	5709	57	0.986	1.106	146	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
RPSA	3921	156	1.327	1.151	152	Yes	-
[ CDS1 ]	1040	1	0.265	0.960	14	-	-
PGD	5226	75	1.201	1.106	138	Yes	-

Interactions (13)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDS1	1040	RPSA	3921	pp	--	int.I2D: YeastMedium
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACACB	32	RPSA	3921	pp	--	int.I2D: IntAct_Yeast, YeastMedium
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACACB	32	PSMD3	5709	pp	--	int.I2D: YeastLow
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
ACACB	32	CDS1	1040	pp	--	int.I2D: YeastMedium
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
ACACB	32	PGD	5226	pp	--	int.I2D: YeastLow

Related GO terms (140)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016071	mRNA metabolic process	3.71e-06	5.35e-02	5.015	4	31	223
GO:0016070	RNA metabolic process	5.57e-06	8.03e-02	4.868	4	32	247
GO:0005838	proteasome regulatory particle	1.77e-05	2.56e-01	8.231	2	7	12
GO:0005829	cytosol	3.14e-05	4.52e-01	2.338	7	132	2496
GO:0022624	proteasome accessory complex	3.65e-05	5.26e-01	7.729	2	8	17
GO:0016032	viral process	1.15e-04	1.00e+00	3.755	4	55	534
GO:0044281	small molecule metabolic process	1.87e-04	1.00e+00	2.896	5	58	1211
GO:0022627	cytosolic small ribosomal subunit	1.97e-04	1.00e+00	6.531	2	4	39
GO:0010467	gene expression	2.77e-04	1.00e+00	3.430	4	59	669
GO:0006521	regulation of cellular amino acid metabolic process	3.25e-04	1.00e+00	6.172	2	17	50
GO:0070062	extracellular vesicular exosome	4.35e-04	1.00e+00	2.172	6	104	2400
GO:0000502	proteasome complex	4.38e-04	1.00e+00	5.958	2	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.33e-04	1.00e+00	5.816	2	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.50e-04	1.00e+00	5.794	2	22	65
GO:0019521	D-gluconate metabolic process	5.55e-04	1.00e+00	10.816	1	1	1
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.38e-04	1.00e+00	5.687	2	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.75e-04	1.00e+00	5.646	2	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.13e-04	1.00e+00	5.607	2	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.32e-04	1.00e+00	5.587	2	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	8.12e-04	1.00e+00	5.512	2	23	79
GO:0019083	viral transcription	8.53e-04	1.00e+00	5.476	2	10	81
GO:0016020	membrane	8.83e-04	1.00e+00	2.423	5	90	1681
GO:0006415	translational termination	9.84e-04	1.00e+00	5.373	2	10	87
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.10e-03	1.00e+00	5.293	2	21	92
GO:2001295	malonyl-CoA biosynthetic process	1.11e-03	1.00e+00	9.816	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1.11e-03	1.00e+00	9.816	1	1	2
GO:0003989	acetyl-CoA carboxylase activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0019322	pentose biosynthetic process	1.11e-03	1.00e+00	9.816	1	2	2
GO:0005055	laminin receptor activity	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006407	rRNA export from nucleus	1.11e-03	1.00e+00	9.816	1	1	2
GO:0006414	translational elongation	1.12e-03	1.00e+00	5.277	2	13	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.40e-03	1.00e+00	5.116	2	10	104
GO:0006084	acetyl-CoA metabolic process	1.66e-03	1.00e+00	9.231	1	1	3
GO:0004142	diacylglycerol cholinephosphotransferase activity	1.66e-03	1.00e+00	9.231	1	1	3
GO:0004605	phosphatidate cytidylyltransferase activity	1.66e-03	1.00e+00	9.231	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	1.66e-03	1.00e+00	9.231	1	2	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	1.66e-03	1.00e+00	9.231	1	1	3
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.68e-03	1.00e+00	4.983	2	11	114
GO:0019058	viral life cycle	1.71e-03	1.00e+00	4.971	2	13	115
GO:0000209	protein polyubiquitination	1.74e-03	1.00e+00	4.958	2	20	116
GO:0044267	cellular protein metabolic process	1.75e-03	1.00e+00	3.512	3	29	474
GO:0006413	translational initiation	2.21e-03	1.00e+00	4.783	2	17	131
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.22e-03	1.00e+00	8.816	1	1	4
GO:0030686	90S preribosome	2.22e-03	1.00e+00	8.816	1	1	4
GO:0003735	structural constituent of ribosome	2.42e-03	1.00e+00	4.718	2	10	137
GO:0043248	proteasome assembly	2.77e-03	1.00e+00	8.494	1	1	5
GO:0004075	biotin carboxylase activity	2.77e-03	1.00e+00	8.494	1	1	5
GO:0009374	biotin binding	2.77e-03	1.00e+00	8.494	1	1	5
GO:0000082	G1/S transition of mitotic cell cycle	2.85e-03	1.00e+00	4.597	2	32	149
GO:0042981	regulation of apoptotic process	2.89e-03	1.00e+00	4.587	2	24	150
GO:0030957	Tat protein binding	3.32e-03	1.00e+00	8.231	1	3	6
GO:0034641	cellular nitrogen compound metabolic process	3.73e-03	1.00e+00	4.398	2	20	171
GO:0006657	CDP-choline pathway	3.88e-03	1.00e+00	8.009	1	2	7
GO:0000028	ribosomal small subunit assembly	3.88e-03	1.00e+00	8.009	1	1	7
GO:0006853	carnitine shuttle	4.43e-03	1.00e+00	7.816	1	1	8
GO:0031325	positive regulation of cellular metabolic process	4.43e-03	1.00e+00	7.816	1	1	8
GO:0070688	MLL5-L complex	4.43e-03	1.00e+00	7.816	1	1	8
GO:0006768	biotin metabolic process	4.98e-03	1.00e+00	7.646	1	1	9
GO:0016024	CDP-diacylglycerol biosynthetic process	5.53e-03	1.00e+00	7.494	1	1	10
GO:0006098	pentose-phosphate shunt	5.53e-03	1.00e+00	7.494	1	4	10
GO:0006412	translation	6.65e-03	1.00e+00	3.971	2	20	230
GO:0030234	enzyme regulator activity	7.19e-03	1.00e+00	7.116	1	3	13
GO:0035267	NuA4 histone acetyltransferase complex	7.74e-03	1.00e+00	7.009	1	4	14
GO:0050998	nitric-oxide synthase binding	8.84e-03	1.00e+00	6.816	1	1	16
GO:0042176	regulation of protein catabolic process	8.84e-03	1.00e+00	6.816	1	3	16
GO:0007602	phototransduction	9.39e-03	1.00e+00	6.729	1	1	17
GO:0048863	stem cell differentiation	1.05e-02	1.00e+00	6.568	1	1	19
GO:0030863	cortical cytoskeleton	1.21e-02	1.00e+00	6.357	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.21e-02	1.00e+00	6.357	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.27e-02	1.00e+00	6.293	1	4	23
GO:0043236	laminin binding	1.27e-02	1.00e+00	6.293	1	1	23
GO:0019843	rRNA binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0043022	ribosome binding	1.49e-02	1.00e+00	6.061	1	3	27
GO:0050661	NADP binding	1.49e-02	1.00e+00	6.061	1	2	27
GO:0031492	nucleosomal DNA binding	1.49e-02	1.00e+00	6.061	1	4	27
GO:0019894	kinesin binding	1.54e-02	1.00e+00	6.009	1	1	28
GO:0005925	focal adhesion	1.63e-02	1.00e+00	3.300	2	19	366
GO:0006633	fatty acid biosynthetic process	1.76e-02	1.00e+00	5.816	1	3	32
GO:0005654	nucleoplasm	1.77e-02	1.00e+00	2.322	3	76	1082
GO:0000278	mitotic cell cycle	1.84e-02	1.00e+00	3.205	2	48	391
GO:0001895	retina homeostasis	1.87e-02	1.00e+00	5.729	1	1	34
GO:0034332	adherens junction organization	1.98e-02	1.00e+00	5.646	1	1	36
GO:0051084	'de novo' posttranslational protein folding	2.03e-02	1.00e+00	5.607	1	4	37
GO:0070527	platelet aggregation	2.09e-02	1.00e+00	5.568	1	2	38
GO:0043066	negative regulation of apoptotic process	2.15e-02	1.00e+00	3.088	2	31	424
GO:0014070	response to organic cyclic compound	2.36e-02	1.00e+00	5.390	1	4	43
GO:0021762	substantia nigra development	2.42e-02	1.00e+00	5.357	1	2	44
GO:0051289	protein homotetramerization	2.79e-02	1.00e+00	5.144	1	1	51
GO:0006661	phosphatidylinositol biosynthetic process	2.85e-02	1.00e+00	5.116	1	2	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.90e-02	1.00e+00	5.088	1	5	53
GO:0045216	cell-cell junction organization	2.96e-02	1.00e+00	5.061	1	2	54
GO:0012505	endomembrane system	3.06e-02	1.00e+00	5.009	1	2	56
GO:0005840	ribosome	3.17e-02	1.00e+00	4.958	1	1	58
GO:0006915	apoptotic process	3.55e-02	1.00e+00	2.700	2	33	555
GO:0006767	water-soluble vitamin metabolic process	3.71e-02	1.00e+00	4.729	1	1	68
GO:0034329	cell junction assembly	3.71e-02	1.00e+00	4.729	1	1	68
GO:0046474	glycerophospholipid biosynthetic process	3.82e-02	1.00e+00	4.687	1	4	70
GO:0006766	vitamin metabolic process	3.87e-02	1.00e+00	4.666	1	1	71
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.03e-02	1.00e+00	4.607	1	6	74
GO:0006928	cellular component movement	4.94e-02	1.00e+00	4.308	1	7	91
GO:0005200	structural constituent of cytoskeleton	4.94e-02	1.00e+00	4.308	1	8	91
GO:0001649	osteoblast differentiation	4.99e-02	1.00e+00	4.293	1	6	92
GO:0006112	energy reserve metabolic process	5.15e-02	1.00e+00	4.246	1	3	95
GO:0014069	postsynaptic density	5.68e-02	1.00e+00	4.102	1	3	105
GO:0005741	mitochondrial outer membrane	5.68e-02	1.00e+00	4.102	1	7	105
GO:0072562	blood microparticle	5.99e-02	1.00e+00	4.022	1	3	111
GO:0030529	ribonucleoprotein complex	6.05e-02	1.00e+00	4.009	1	8	112
GO:0006325	chromatin organization	6.36e-02	1.00e+00	3.933	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	6.78e-02	1.00e+00	3.839	1	5	126
GO:0006644	phospholipid metabolic process	6.94e-02	1.00e+00	3.805	1	5	129
GO:0000790	nuclear chromatin	6.94e-02	1.00e+00	3.805	1	9	129
GO:0005634	nucleus	7.14e-02	1.00e+00	0.984	5	136	4559
GO:0044255	cellular lipid metabolic process	7.15e-02	1.00e+00	3.761	1	6	133
GO:0006457	protein folding	7.66e-02	1.00e+00	3.656	1	7	143
GO:0061024	membrane organization	7.77e-02	1.00e+00	3.636	1	7	145
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	8.80e-02	1.00e+00	3.450	1	7	165
GO:0030424	axon	8.85e-02	1.00e+00	3.441	1	4	166
GO:0044822	poly(A) RNA binding	1.12e-01	1.00e+00	1.772	2	49	1056
GO:0005975	carbohydrate metabolic process	1.32e-01	1.00e+00	2.833	1	9	253
GO:0042493	response to drug	1.47e-01	1.00e+00	2.666	1	13	284
GO:0005856	cytoskeleton	1.50e-01	1.00e+00	2.631	1	12	291
GO:0043234	protein complex	1.52e-01	1.00e+00	2.612	1	18	295
GO:0005524	ATP binding	1.58e-01	1.00e+00	1.474	2	60	1298
GO:0019901	protein kinase binding	1.63e-01	1.00e+00	2.508	1	21	317
GO:0007411	axon guidance	1.64e-01	1.00e+00	2.499	1	13	319
GO:0007155	cell adhesion	1.87e-01	1.00e+00	2.289	1	6	369
GO:0005515	protein binding	2.02e-01	1.00e+00	0.582	5	184	6024
GO:0055114	oxidation-reduction process	2.11e-01	1.00e+00	2.102	1	12	420
GO:0007596	blood coagulation	2.26e-01	1.00e+00	1.986	1	18	455
GO:0005783	endoplasmic reticulum	2.70e-01	1.00e+00	1.697	1	10	556
GO:0005789	endoplasmic reticulum membrane	2.76e-01	1.00e+00	1.661	1	16	570
GO:0045087	innate immune response	2.87e-01	1.00e+00	1.597	1	24	596
GO:0005737	cytoplasm	3.49e-01	1.00e+00	0.522	3	110	3767
GO:0007165	signal transduction	4.05e-01	1.00e+00	0.991	1	24	907
GO:0005615	extracellular space	4.23e-01	1.00e+00	0.914	1	17	957
GO:0005739	mitochondrion	4.37e-01	1.00e+00	0.853	1	28	998
GO:0046872	metal ion binding	5.32e-01	1.00e+00	0.464	1	25	1307
GO:0005730	nucleolus	6.20e-01	1.00e+00	0.136	1	69	1641
GO:0016021	integral component of membrane	6.94e-01	1.00e+00	-0.137	1	27	1982
GO:0005886	plasma membrane	7.94e-01	1.00e+00	-0.518	1	45	2582

Wolf-ratios-Mammosphere-Adherent

int-snw-1040

Statistics

Genes (8)

Interactions (13)

Related GO terms (140)