meta-reg-snw-27130

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-4831 tai-screen-luciferase 6.314 3.38e-133 5.36e-07 3.08e-03 24 20
reg-snw-27130 tai-screen-luciferase 4.707 1.89e-24 5.18e-04 8.42e-04 7 4
int-snw-51741 tai-screen-luciferase 6.174 2.67e-126 1.32e-06 4.54e-03 24 19
tai-screen-luciferase-meta-reg-snw-27130 subnetwork

Genes (40)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS20 6224 22-4.7576.314153Yes-
RPS8 6202 33-5.5457.555234--
MAPK8 5599 28-4.4036.468153--
CHMP2A 27243 33-9.0377.55541YesYes
RPS15 6209 30-5.0407.011116Yes-
COPA 1314 48-9.3955.672340YesYes
RNF20 56254 28-4.5646.17418--
CUL4B 8450 21-2.8095.269142--
HSF1 3297 46-4.1795.027209-Yes
SPDL1 54908 3-3.3764.70731YesYes
SRC 6714 28-2.8066.174419Yes-
INVS 27130 31.9504.70729--
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RPS16 6217 38-5.4444.880205--
CDC42 998 44-6.9604.707276YesYes
RPS11 6205 44-6.5887.555175Yes-
NME2 4831 24-3.0344.32553--
RPS6 6194 44-5.6038.046217Yes-
UBB 7314 30-4.2896.428147--
COPB1 1315 39-6.2219.063118YesYes
RPS23 6228 21-4.4856.375118Yes-
SERBP1 26135 35-4.6125.516106-Yes
RPS13 6207 43-6.5897.555174Yes-
PRIM2 5558 6-3.5075.26967--
RPS24 6229 46-7.0348.389217Yes-
VIM 7431 18-3.7606.428246--
TCERG1 10915 28-3.8086.17458Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS3A 6189 19-4.6477.189166Yes-
RPS4X 6191 44-6.7477.555263Yes-
COPZ1 22818 48-8.3019.06313YesYes
RPS15A 6210 36-5.4137.555177Yes-
WWOX 51741 28-2.4486.17438--
RPS27A 6233 45-5.6318.389344Yes-
RPS14 6208 23-4.8037.011204Yes-
RPS19 6223 21-4.7014.752102Yes-
NFKBIB 4793 28-3.9786.17478--
RPS26 6231 43-7.4788.04660Yes-
ARCN1 372 48-8.2329.063118YesYes

Interactions (118)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS20 6224 RPS26 6231 pp -- int.I2D: YeastLow
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
NME2 4831 RPS19 6223 pp -- int.Proteinpedia: Mass spectrometry
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
VIM 7431 SERBP1 26135 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, HPRD, BioGrid, MINT, StelzlHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
RPS11 6205 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS11 6205 RPS19 6223 pp -- int.I2D: IntAct_Yeast
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
TCERG1 10915 WWOX 51741 pp -- int.I2D: BioGrid, MINT, Pawson1;
int.Mint: MI:0915(physical association)
RPS3A 6189 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 INVS 27130 pd <> reg.ITFP.txt: no annot
RPS13 6207 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
SRC 6714 CKAP5 9793 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
RPS15 6209 RPS23 6228 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS14 6208 RPS20 6224 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
CDC42 998 UBB 7314 pp -- int.I2D: SOURAV_MAPK_HIGH
NFKBIB 4793 UBB 7314 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS15 6209 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS20 6224 RPS23 6228 pp -- int.I2D: YeastMedium, INTEROLOG
NME2 4831 RPS16 6217 pp -- int.Proteinpedia: Mass spectrometry
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS20 6224 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS23 6228 pp -- int.I2D: YeastLow, BioGrid_Yeast
RPS6 6194 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS23 6228 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS9 6203 pp -- int.I2D: IntAct
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
CKAP5 9793 SPDL1 54908 pd > reg.ITFP.txt: no annot
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
UBB 7314 WWOX 51741 pp -- int.I2D: BCI, HPRD;
int.HPRD: in vivo
UBB 7314 RNF20 56254 pp -- int.Intact: MI:0220(ubiquitination reaction);
int.I2D: IntAct
RPS15A 6210 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
SRC 6714 WWOX 51741 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS20 6224 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastHigh, YeastMedium
RPS13 6207 RPS19 6223 pp -- int.I2D: IntAct_Yeast
RPS20 6224 RPS27A 6233 pp -- int.I2D: YeastLow
RPS4X 6191 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 UBB 7314 pp -- int.I2D: BIND
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
NME2 4831 VIM 7431 pp -- int.HPRD: in vivo
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS13 6207 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS8 6202 RPS19 6223 pp -- int.I2D: MINT
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS4X 6191 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS23 6228 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
HSF1 3297 MAPK8 5599 pp -- int.I2D: HPRD, INNATEDB;
int.HPRD: in vitro, in vivo
RPS3A 6189 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS19 6223 INVS 27130 pd < reg.ITFP.txt: no annot
RPS6 6194 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)
RPS15 6209 RPS16 6217 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS3A 6189 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
INVS 27130 SPDL1 54908 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS11 6205 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
COPA 1314 CUL4B 8450 pd <> reg.ITFP.txt: no annot
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS15A 6210 pp -- int.I2D: YeastMedium, INTEROLOG
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 RPS3A 6189 pp -- int.I2D: IntAct_Yeast
RPS16 6217 RPS23 6228 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS20 6224 pp -- int.I2D: YeastLow
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
MAPK8 5599 WWOX 51741 pp -- int.I2D: MINT, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
PRIM2 5558 CUL4B 8450 pd < reg.ITFP.txt: no annot
RPS11 6205 RPS20 6224 pp -- int.I2D: YeastMedium, INTEROLOG
RPS13 6207 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS6 6194 pp -- int.I2D: BioGrid_Yeast, YeastLow

Related GO terms (520)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit3.81e-366.22e-327.475172139
GO:0019058viral life cycle3.16e-315.15e-276.0751925115
GO:0019083viral transcription9.07e-301.48e-256.420172281
GO:0006415translational termination3.47e-295.66e-256.317172287
GO:0006414translational elongation1.20e-281.96e-246.221172293
GO:0006614SRP-dependent cotranslational protein targeting to membrane9.41e-281.54e-236.0601722104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay5.02e-278.20e-235.9271722114
GO:0006413translational initiation6.18e-261.01e-215.7271727131
GO:0003735structural constituent of ribosome2.31e-253.77e-215.6201724141
GO:0016071mRNA metabolic process1.20e-231.95e-195.0421829223
GO:0016070RNA metabolic process7.84e-231.28e-184.8941829247
GO:0016032viral process1.16e-221.89e-184.0552237540
GO:0006412translation1.81e-212.96e-174.8831729235
GO:0005829cytosol1.45e-202.36e-162.39433742562
GO:0044267cellular protein metabolic process5.52e-169.02e-123.8091729495
GO:0016020membrane3.74e-156.11e-112.54725481746
GO:0010467gene expression4.15e-156.78e-113.4571836669
GO:0044822poly(A) RNA binding8.15e-141.33e-092.92020421078
GO:0015935small ribosomal subunit1.78e-122.90e-087.1706917
GO:0005925focal adhesion2.34e-123.83e-083.8421323370
GO:0042274ribosomal small subunit biogenesis5.34e-118.71e-077.4095612
GO:0061024membrane organization6.18e-111.01e-064.653911146
GO:0048205COPI coating of Golgi vesicle8.66e-111.41e-067.2945613
GO:0030126COPI vesicle coat8.66e-111.41e-067.2945613
GO:0006890retrograde vesicle-mediated transport, Golgi to ER3.50e-095.71e-056.3515625
GO:0005840ribosome6.00e-099.79e-055.37561059
GO:0070062extracellular vesicular exosome8.36e-091.36e-041.83522512516
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.36e-072.22e-037.936335
GO:0000028ribosomal small subunit assembly4.74e-077.74e-037.450337
GO:0006364rRNA processing3.54e-065.78e-024.4095896
GO:0005515protein binding7.41e-061.21e-010.95029876127
GO:0030529ribonucleoprotein complex8.24e-061.35e-014.16258114
GO:0006891intra-Golgi vesicle-mediated transport9.06e-061.48e-016.1703317
GO:0034146toll-like receptor 5 signaling pathway1.88e-053.07e-014.6504565
GO:0034166toll-like receptor 10 signaling pathway1.88e-053.07e-014.6504565
GO:0036464cytoplasmic ribonucleoprotein granule2.03e-053.32e-015.7983522
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway2.67e-054.36e-014.5234571
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway2.67e-054.36e-014.5234571
GO:0034162toll-like receptor 9 signaling pathway2.82e-054.60e-014.5034572
GO:0034134toll-like receptor 2 signaling pathway2.98e-054.86e-014.4834573
GO:0005737cytoplasm3.10e-055.05e-011.17522653976
GO:0035666TRIF-dependent toll-like receptor signaling pathway3.49e-055.70e-014.4254576
GO:0030490maturation of SSU-rRNA3.50e-055.72e-017.673224
GO:0019843rRNA binding3.83e-056.25e-015.5033427
GO:0002756MyD88-independent toll-like receptor signaling pathway3.87e-056.32e-014.3874578
GO:0002755MyD88-dependent toll-like receptor signaling pathway4.28e-056.98e-014.3514580
GO:0034138toll-like receptor 3 signaling pathway4.28e-056.98e-014.3514580
GO:0033119negative regulation of RNA splicing5.83e-059.51e-017.351225
GO:0006886intracellular protein transport6.15e-051.00e+003.56056173
GO:0043066negative regulation of apoptotic process7.70e-051.00e+002.722714433
GO:0045182translation regulator activity8.73e-051.00e+007.088226
GO:0034142toll-like receptor 4 signaling pathway8.73e-051.00e+004.0884596
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway9.21e-051.00e+005.0883336
GO:0002224toll-like receptor signaling pathway1.43e-041.00e+003.90445109
GO:0007254JNK cascade2.62e-041.00e+004.5853351
GO:0051403stress-activated MAPK cascade3.10e-041.00e+004.5033454
GO:0019082viral protein processing3.81e-041.00e+006.0882212
GO:0016197endosomal transport3.83e-041.00e+004.3993358
GO:0032481positive regulation of type I interferon production4.45e-041.00e+004.3273361
GO:0032479regulation of type I interferon production4.49e-041.00e+005.9722213
GO:0071398cellular response to fatty acid4.49e-041.00e+005.9722213
GO:0000082G1/S transition of mitotic cell cycle4.84e-041.00e+003.444411150
GO:0005730nucleolus4.98e-041.00e+001.54012361684
GO:0043065positive regulation of apoptotic process5.23e-041.00e+002.89656274
GO:0043005neuron projection6.32e-041.00e+003.34246161
GO:0075733intracellular transport of virus7.78e-041.00e+005.5852317
GO:0019068virion assembly7.78e-041.00e+005.5852217
GO:0007173epidermal growth factor receptor signaling pathway1.19e-031.00e+003.09545191
GO:0007220Notch receptor processing1.31e-031.00e+005.2132222
GO:0001649osteoblast differentiation1.61e-031.00e+003.6883395
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway1.70e-031.00e+005.0292225
GO:0005844polysome1.70e-031.00e+005.0292225
GO:0071456cellular response to hypoxia1.77e-031.00e+003.6433398
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia1.83e-031.00e+004.9722226
GO:0005978glycogen biosynthetic process1.83e-031.00e+004.9722226
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity1.83e-031.00e+004.9722226
GO:2001286regulation of caveolin-mediated endocytosis2.45e-031.00e+008.673111
GO:0071393cellular response to progesterone stimulus2.45e-031.00e+008.673111
GO:0004673protein histidine kinase activity2.45e-031.00e+008.673111
GO:0022605oogenesis stage2.45e-031.00e+008.673111
GO:0018106peptidyl-histidine phosphorylation2.45e-031.00e+008.673111
GO:0021691cerebellar Purkinje cell layer maturation2.45e-031.00e+008.673111
GO:0000278mitotic cell cycle2.74e-031.00e+002.358516398
GO:0032480negative regulation of type I interferon production2.77e-031.00e+004.6732232
GO:0097190apoptotic signaling pathway2.85e-031.00e+003.39933116
GO:0000209protein polyubiquitination2.85e-031.00e+003.39937116
GO:0034332adherens junction organization3.50e-031.00e+004.5032436
GO:0051092positive regulation of NF-kappaB transcription factor activity3.52e-031.00e+003.29233125
GO:0045087innate immune response3.63e-031.00e+001.991611616
GO:0030218erythrocyte differentiation3.89e-031.00e+004.4252238
GO:0007179transforming growth factor beta receptor signaling pathway3.93e-031.00e+003.23534130
GO:0048011neurotrophin TRK receptor signaling pathway4.36e-031.00e+002.58045273
GO:0007249I-kappaB kinase/NF-kappaB signaling4.52e-031.00e+004.3152441
GO:0000086G2/M transition of mitotic cell cycle4.56e-031.00e+003.15936137
GO:0060661submandibular salivary gland formation4.90e-031.00e+007.673112
GO:1902255positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator4.90e-031.00e+007.673112
GO:0002762negative regulation of myeloid leukocyte differentiation4.90e-031.00e+007.673112
GO:1990077primosome complex4.90e-031.00e+007.673122
GO:0071338positive regulation of hair follicle cell proliferation4.90e-031.00e+007.673112
GO:0010632regulation of epithelial cell migration4.90e-031.00e+007.673112
GO:0090135actin filament branching4.90e-031.00e+007.673112
GO:0060265positive regulation of respiratory burst involved in inflammatory response4.90e-031.00e+007.673112
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway4.96e-031.00e+004.2462243
GO:0010628positive regulation of gene expression5.75e-031.00e+003.03834149
GO:0042981regulation of apoptotic process5.97e-031.00e+003.01937151
GO:0005198structural molecule activity6.88e-031.00e+002.94535159
GO:0008543fibroblast growth factor receptor signaling pathway6.88e-031.00e+002.94533159
GO:0010641positive regulation of platelet-derived growth factor receptor signaling pathway7.33e-031.00e+007.088113
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding7.33e-031.00e+007.088113
GO:0003161cardiac conduction system development7.33e-031.00e+007.088113
GO:0090045positive regulation of deacetylase activity7.33e-031.00e+007.088113
GO:0035033histone deacetylase regulator activity7.33e-031.00e+007.088113
GO:2000017positive regulation of determination of dorsal identity7.33e-031.00e+007.088113
GO:0051683establishment of Golgi localization7.33e-031.00e+007.088123
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity7.33e-031.00e+007.088113
GO:0033146regulation of intracellular estrogen receptor signaling pathway7.33e-031.00e+007.088113
GO:0000056ribosomal small subunit export from nucleus7.33e-031.00e+007.088123
GO:0004705JUN kinase activity7.33e-031.00e+007.088113
GO:0060266negative regulation of respiratory burst involved in inflammatory response7.33e-031.00e+007.088113
GO:0019901protein kinase binding7.60e-031.00e+002.35149320
GO:0030666endocytic vesicle membrane7.73e-031.00e+003.9182254
GO:0038095Fc-epsilon receptor signaling pathway8.40e-031.00e+002.84033171
GO:0034191apolipoprotein A-I receptor binding9.77e-031.00e+006.673114
GO:0007000nucleolus organization9.77e-031.00e+006.673124
GO:0032463negative regulation of protein homooligomerization9.77e-031.00e+006.673114
GO:0051902negative regulation of mitochondrial depolarization9.77e-031.00e+006.673114
GO:0060020Bergmann glial cell differentiation9.77e-031.00e+006.673114
GO:0031062positive regulation of histone methylation9.77e-031.00e+006.673114
GO:0060684epithelial-mesenchymal cell signaling9.77e-031.00e+006.673114
GO:0070851growth factor receptor binding9.77e-031.00e+006.673114
GO:0051835positive regulation of synapse structural plasticity9.77e-031.00e+006.673114
GO:0090231regulation of spindle checkpoint9.77e-031.00e+006.673114
GO:0072384organelle transport along microtubule9.77e-031.00e+006.673124
GO:0003896DNA primase activity9.77e-031.00e+006.673124
GO:0007258JUN phosphorylation9.77e-031.00e+006.673114
GO:0031577spindle checkpoint9.77e-031.00e+006.673114
GO:0048664neuron fate determination9.77e-031.00e+006.673114
GO:0033503HULC complex9.77e-031.00e+006.673114
GO:0045682regulation of epidermis development9.77e-031.00e+006.673114
GO:0031063regulation of histone deacetylation9.77e-031.00e+006.673114
GO:0033625positive regulation of integrin activation9.77e-031.00e+006.673114
GO:0009991response to extracellular stimulus9.77e-031.00e+006.673114
GO:0043515kinetochore binding9.77e-031.00e+006.673114
GO:0006417regulation of translation1.04e-021.00e+003.6952463
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.07e-021.00e+003.6732264
GO:0003723RNA binding1.09e-021.00e+002.201410355
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.11e-021.00e+003.6502665
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.11e-021.00e+003.6502665
GO:0005882intermediate filament1.14e-021.00e+003.6282366
GO:0031295T cell costimulation1.17e-021.00e+003.6062367
GO:2000641regulation of early endosome to late endosome transport1.22e-021.00e+006.351115
GO:0036336dendritic cell migration1.22e-021.00e+006.351115
GO:0035088establishment or maintenance of apical/basal cell polarity1.22e-021.00e+006.351115
GO:0051385response to mineralocorticoid1.22e-021.00e+006.351115
GO:0006269DNA replication, synthesis of RNA primer1.22e-021.00e+006.351125
GO:1902188positive regulation of viral release from host cell1.22e-021.00e+006.351115
GO:0097300programmed necrotic cell death1.22e-021.00e+006.351115
GO:0031256leading edge membrane1.22e-021.00e+006.351115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.22e-021.00e+006.351115
GO:0060971embryonic heart tube left/right pattern formation1.22e-021.00e+006.351115
GO:0071803positive regulation of podosome assembly1.22e-021.00e+006.351115
GO:0018105peptidyl-serine phosphorylation1.24e-021.00e+003.5642569
GO:0005634nucleus1.26e-021.00e+000.68319664828
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.27e-021.00e+003.5432870
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.38e-021.00e+003.4832673
GO:0003729mRNA binding1.38e-021.00e+003.4832373
GO:0000122negative regulation of transcription from RNA polymerase II promoter1.40e-021.00e+001.79259589
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.42e-021.00e+003.4632874
GO:0050847progesterone receptor signaling pathway1.46e-021.00e+006.088116
GO:0007143female meiotic division1.46e-021.00e+006.088116
GO:0002309T cell proliferation involved in immune response1.46e-021.00e+006.088116
GO:0045056transcytosis1.46e-021.00e+006.088116
GO:0060789hair follicle placode formation1.46e-021.00e+006.088116
GO:0048554positive regulation of metalloenzyme activity1.46e-021.00e+006.088116
GO:0050792regulation of viral process1.46e-021.00e+006.088116
GO:0002181cytoplasmic translation1.46e-021.00e+006.088126
GO:0019215intermediate filament binding1.46e-021.00e+006.088116
GO:0006924activation-induced cell death of T cells1.46e-021.00e+006.088126
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.53e-021.00e+003.4062677
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.53e-021.00e+003.4062477
GO:0007229integrin-mediated signaling pathway1.56e-021.00e+003.3872278
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.60e-021.00e+003.3692879
GO:0010629negative regulation of gene expression1.64e-021.00e+003.3512280
GO:0071222cellular response to lipopolysaccharide1.68e-021.00e+003.3332481
GO:0010447response to acidic pH1.70e-021.00e+005.865117
GO:0009142nucleoside triphosphate biosynthetic process1.70e-021.00e+005.865117
GO:0060136embryonic process involved in female pregnancy1.70e-021.00e+005.865117
GO:0043497regulation of protein heterodimerization activity1.70e-021.00e+005.865117
GO:0050658RNA transport1.70e-021.00e+005.865117
GO:0048027mRNA 5'-UTR binding1.70e-021.00e+005.865117
GO:0007097nuclear migration1.70e-021.00e+005.865127
GO:0003334keratinocyte development1.70e-021.00e+005.865117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.70e-021.00e+005.865117
GO:0070914UV-damage excision repair1.70e-021.00e+005.865117
GO:0034101erythrocyte homeostasis1.70e-021.00e+005.865117
GO:0010907positive regulation of glucose metabolic process1.70e-021.00e+005.865117
GO:0030157pancreatic juice secretion1.70e-021.00e+005.865117
GO:0000930gamma-tubulin complex1.70e-021.00e+005.865117
GO:0039702viral budding via host ESCRT complex1.94e-021.00e+005.673118
GO:0006183GTP biosynthetic process1.94e-021.00e+005.673118
GO:0043114regulation of vascular permeability1.94e-021.00e+005.673118
GO:0034501protein localization to kinetochore1.94e-021.00e+005.673118
GO:0045124regulation of bone resorption1.94e-021.00e+005.673118
GO:0051489regulation of filopodium assembly1.94e-021.00e+005.673118
GO:0033523histone H2B ubiquitination1.94e-021.00e+005.673118
GO:0007172signal complex assembly1.94e-021.00e+005.673118
GO:0050852T cell receptor signaling pathway1.96e-021.00e+003.2132288
GO:0000187activation of MAPK activity2.05e-021.00e+003.1812390
GO:0003713transcription coactivator activity2.06e-021.00e+002.35736239
GO:0000922spindle pole2.09e-021.00e+003.1652591
GO:0000940condensed chromosome outer kinetochore2.18e-021.00e+005.503119
GO:0071732cellular response to nitric oxide2.18e-021.00e+005.503119
GO:0006241CTP biosynthetic process2.18e-021.00e+005.503119
GO:0014075response to amine2.18e-021.00e+005.503119
GO:0006228UTP biosynthetic process2.18e-021.00e+005.503119
GO:0090136epithelial cell-cell adhesion2.18e-021.00e+005.503129
GO:0047497mitochondrion transport along microtubule2.18e-021.00e+005.503119
GO:0046628positive regulation of insulin receptor signaling pathway2.18e-021.00e+005.503119
GO:0002474antigen processing and presentation of peptide antigen via MHC class I2.22e-021.00e+003.1182794
GO:0045618positive regulation of keratinocyte differentiation2.42e-021.00e+005.3511110
GO:0070307lens fiber cell development2.42e-021.00e+005.3511110
GO:0005798Golgi-associated vesicle2.42e-021.00e+005.3511110
GO:0031274positive regulation of pseudopodium assembly2.42e-021.00e+005.3511210
GO:0022407regulation of cell-cell adhesion2.42e-021.00e+005.3511110
GO:0060047heart contraction2.42e-021.00e+005.3511110
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity2.66e-021.00e+005.2131111
GO:0051895negative regulation of focal adhesion assembly2.66e-021.00e+005.2131111
GO:0045120pronucleus2.66e-021.00e+005.2131111
GO:2000573positive regulation of DNA biosynthetic process2.66e-021.00e+005.2131211
GO:0051272positive regulation of cellular component movement2.66e-021.00e+005.2131111
GO:0045109intermediate filament organization2.66e-021.00e+005.2131111
GO:0060065uterus development2.66e-021.00e+005.2131111
GO:0010390histone monoubiquitination2.66e-021.00e+005.2131111
GO:0035518histone H2A monoubiquitination2.66e-021.00e+005.2131211
GO:0014002astrocyte development2.66e-021.00e+005.2131111
GO:0061136regulation of proteasomal protein catabolic process2.90e-021.00e+005.0881112
GO:0007051spindle organization2.90e-021.00e+005.0881112
GO:0043149stress fiber assembly2.90e-021.00e+005.0881212
GO:1903543positive regulation of exosomal secretion2.90e-021.00e+005.0881112
GO:1901214regulation of neuron death2.90e-021.00e+005.0881112
GO:0005815microtubule organizing center2.97e-021.00e+002.89124110
GO:0043488regulation of mRNA stability3.14e-021.00e+004.9721113
GO:0031929TOR signaling3.14e-021.00e+004.9721113
GO:0007080mitotic metaphase plate congression3.14e-021.00e+004.9721113
GO:1900087positive regulation of G1/S transition of mitotic cell cycle3.14e-021.00e+004.9721113
GO:0060444branching involved in mammary gland duct morphogenesis3.14e-021.00e+004.9721113
GO:0019899enzyme binding3.32e-021.00e+002.08835288
GO:0035371microtubule plus-end3.38e-021.00e+004.8651114
GO:0031333negative regulation of protein complex assembly3.38e-021.00e+004.8651114
GO:0050662coenzyme binding3.38e-021.00e+004.8651114
GO:0031996thioesterase binding3.38e-021.00e+004.8651114
GO:0006165nucleoside diphosphate phosphorylation3.38e-021.00e+004.8651114
GO:0006006glucose metabolic process3.43e-021.00e+002.77824119
GO:0048477oogenesis3.62e-021.00e+004.7661115
GO:0030131clathrin adaptor complex3.62e-021.00e+004.7661115
GO:0030225macrophage differentiation3.62e-021.00e+004.7661115
GO:0004550nucleoside diphosphate kinase activity3.62e-021.00e+004.7661115
GO:0048821erythrocyte development3.62e-021.00e+004.7661215
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand3.62e-021.00e+004.7661115
GO:0031369translation initiation factor binding3.62e-021.00e+004.7661215
GO:0051233spindle midzone3.62e-021.00e+004.7661215
GO:0007219Notch signaling pathway3.76e-021.00e+002.70724125
GO:0014911positive regulation of smooth muscle cell migration3.85e-021.00e+004.6731116
GO:0048037cofactor binding3.85e-021.00e+004.6731116
GO:0000132establishment of mitotic spindle orientation3.85e-021.00e+004.6731216
GO:0042176regulation of protein catabolic process3.85e-021.00e+004.6731416
GO:2000811negative regulation of anoikis3.85e-021.00e+004.6731116
GO:0005212structural constituent of eye lens3.85e-021.00e+004.6731116
GO:0006511ubiquitin-dependent protein catabolic process3.87e-021.00e+002.68423127
GO:0002548monocyte chemotaxis4.09e-021.00e+004.5851117
GO:0030742GTP-dependent protein binding4.09e-021.00e+004.5851117
GO:0009615response to virus4.15e-021.00e+002.62824132
GO:0070064proline-rich region binding4.32e-021.00e+004.5031118
GO:0031954positive regulation of protein autophosphorylation4.32e-021.00e+004.5031118
GO:0015949nucleobase-containing small molecule interconversion4.32e-021.00e+004.5031118
GO:0043015gamma-tubulin binding4.32e-021.00e+004.5031218
GO:0090316positive regulation of intracellular protein transport4.32e-021.00e+004.5031118
GO:0007088regulation of mitosis4.56e-021.00e+004.4251119
GO:0017134fibroblast growth factor binding4.56e-021.00e+004.4251219
GO:0045453bone resorption4.56e-021.00e+004.4251119
GO:0031667response to nutrient levels4.56e-021.00e+004.4251119
GO:0016055Wnt signaling pathway4.67e-021.00e+002.53323141
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.68e-021.00e+001.331511811
GO:0032148activation of protein kinase B activity4.79e-021.00e+004.3511120
GO:0051090regulation of sequence-specific DNA binding transcription factor activity4.79e-021.00e+004.3511220
GO:0043473pigmentation4.79e-021.00e+004.3511220
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator4.79e-021.00e+004.3511120
GO:0043393regulation of protein binding4.79e-021.00e+004.3511220
GO:0006915apoptotic process5.02e-021.00e+001.51549571
GO:0007369gastrulation5.03e-021.00e+004.2801121
GO:0046847filopodium assembly5.03e-021.00e+004.2801121
GO:0051881regulation of mitochondrial membrane potential5.03e-021.00e+004.2801121
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling5.09e-021.00e+002.46323148
GO:2001243negative regulation of intrinsic apoptotic signaling pathway5.26e-021.00e+004.2131122
GO:0046686response to cadmium ion5.26e-021.00e+004.2131122
GO:0033574response to testosterone5.26e-021.00e+004.2131122
GO:0031016pancreas development5.26e-021.00e+004.2131122
GO:0001106RNA polymerase II transcription corepressor activity5.26e-021.00e+004.2131122
GO:0031435mitogen-activated protein kinase kinase kinase binding5.26e-021.00e+004.2131122
GO:0032201telomere maintenance via semi-conservative replication5.26e-021.00e+004.2131222
GO:0006270DNA replication initiation5.26e-021.00e+004.2131222
GO:1900026positive regulation of substrate adhesion-dependent cell spreading5.49e-021.00e+004.1491123
GO:0071944cell periphery5.49e-021.00e+004.1491123
GO:0045787positive regulation of cell cycle5.49e-021.00e+004.1491223
GO:0002040sprouting angiogenesis5.49e-021.00e+004.1491123
GO:0051017actin filament bundle assembly5.49e-021.00e+004.1491123
GO:0001892embryonic placenta development5.49e-021.00e+004.1491123
GO:0051297centrosome organization5.49e-021.00e+004.1491223
GO:0010008endosome membrane5.65e-021.00e+002.37822157
GO:0007163establishment or maintenance of cell polarity5.72e-021.00e+004.0881224
GO:0051602response to electrical stimulus5.72e-021.00e+004.0881124
GO:0008022protein C-terminus binding5.91e-021.00e+002.34224161
GO:0050715positive regulation of cytokine secretion5.95e-021.00e+004.0291125
GO:0048705skeletal system morphogenesis5.95e-021.00e+004.0291125
GO:0045859regulation of protein kinase activity6.19e-021.00e+003.9721126
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway6.19e-021.00e+003.9721126
GO:0000722telomere maintenance via recombination6.19e-021.00e+003.9721226
GO:0034220ion transmembrane transport6.30e-021.00e+002.28922167
GO:0051149positive regulation of muscle cell differentiation6.42e-021.00e+003.9181227
GO:0032720negative regulation of tumor necrosis factor production6.42e-021.00e+003.9181127
GO:2001238positive regulation of extrinsic apoptotic signaling pathway6.42e-021.00e+003.9181127
GO:0031424keratinization6.42e-021.00e+003.9181127
GO:0001103RNA polymerase II repressing transcription factor binding6.42e-021.00e+003.9181127
GO:0030331estrogen receptor binding6.42e-021.00e+003.9181127
GO:0045184establishment of protein localization6.42e-021.00e+003.9181227
GO:0031069hair follicle morphogenesis6.42e-021.00e+003.9181127
GO:0032467positive regulation of cytokinesis6.65e-021.00e+003.8651128
GO:0031252cell leading edge6.87e-021.00e+003.8151329
GO:0003730mRNA 3'-UTR binding6.87e-021.00e+003.8151129
GO:0034605cellular response to heat6.87e-021.00e+003.8151129
GO:0072686mitotic spindle6.87e-021.00e+003.8151129
GO:0007049cell cycle6.98e-021.00e+002.20524177
GO:0008284positive regulation of cell proliferation7.07e-021.00e+001.64337392
GO:0010977negative regulation of neuron projection development7.10e-021.00e+003.7661230
GO:0051262protein tetramerization7.10e-021.00e+003.7661130
GO:0046875ephrin receptor binding7.10e-021.00e+003.7661230
GO:0042169SH2 domain binding7.10e-021.00e+003.7661130
GO:0031647regulation of protein stability7.10e-021.00e+003.7661130
GO:0040018positive regulation of multicellular organism growth7.10e-021.00e+003.7661130
GO:0031625ubiquitin protein ligase binding7.18e-021.00e+002.18124180
GO:0070555response to interleukin-17.33e-021.00e+003.7181131
GO:0006271DNA strand elongation involved in DNA replication7.33e-021.00e+003.7181231
GO:0007093mitotic cell cycle checkpoint7.33e-021.00e+003.7181231
GO:0006367transcription initiation from RNA polymerase II promoter7.46e-021.00e+002.14925184
GO:0051219phosphoprotein binding7.56e-021.00e+003.6731432
GO:0032091negative regulation of protein binding7.79e-021.00e+003.6281133
GO:0005158insulin receptor binding7.79e-021.00e+003.6281233
GO:0033077T cell differentiation in thymus7.79e-021.00e+003.6281133
GO:0048812neuron projection morphogenesis7.79e-021.00e+003.6281133
GO:0001890placenta development8.01e-021.00e+003.5851134
GO:0097110scaffold protein binding8.01e-021.00e+003.5851134
GO:0042692muscle cell differentiation8.01e-021.00e+003.5851234
GO:0071333cellular response to glucose stimulus8.24e-021.00e+003.5431235
GO:2001237negative regulation of extrinsic apoptotic signaling pathway8.24e-021.00e+003.5431135
GO:0030178negative regulation of Wnt signaling pathway8.46e-021.00e+003.5031136
GO:0071560cellular response to transforming growth factor beta stimulus8.46e-021.00e+003.5031136
GO:0016301kinase activity8.69e-021.00e+003.4631237
GO:0018107peptidyl-threonine phosphorylation8.69e-021.00e+003.4631137
GO:0032880regulation of protein localization8.69e-021.00e+003.4631137
GO:00515394 iron, 4 sulfur cluster binding8.69e-021.00e+003.4631137
GO:0030049muscle filament sliding8.91e-021.00e+003.4251238
GO:0097191extrinsic apoptotic signaling pathway8.91e-021.00e+003.4251338
GO:0045740positive regulation of DNA replication8.91e-021.00e+003.4251138
GO:0021766hippocampus development9.14e-021.00e+003.3871339
GO:0042542response to hydrogen peroxide9.36e-021.00e+003.3511140
GO:0070301cellular response to hydrogen peroxide9.58e-021.00e+003.3151141
GO:0045785positive regulation of cell adhesion9.58e-021.00e+003.3151141
GO:0005902microvillus9.80e-021.00e+003.2801142
GO:0004715non-membrane spanning protein tyrosine kinase activity9.80e-021.00e+003.2801142
GO:0005080protein kinase C binding1.02e-011.00e+003.2131144
GO:0034613cellular protein localization1.02e-011.00e+003.2131244
GO:0009411response to UV1.05e-011.00e+003.1811245
GO:0051591response to cAMP1.05e-011.00e+003.1811145
GO:0044297cell body1.07e-011.00e+003.1491146
GO:0043525positive regulation of neuron apoptotic process1.07e-011.00e+003.1491246
GO:0045727positive regulation of translation1.07e-011.00e+003.1491146
GO:0021762substantia nigra development1.07e-011.00e+003.1491246
GO:0043406positive regulation of MAP kinase activity1.09e-011.00e+003.1181147
GO:0019221cytokine-mediated signaling pathway1.09e-011.00e+001.82725230
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.09e-011.00e+003.1181147
GO:0008344adult locomotory behavior1.09e-011.00e+003.1181247
GO:0007067mitotic nuclear division1.10e-011.00e+001.82127231
GO:0006950response to stress1.11e-011.00e+003.0881148
GO:0005739mitochondrion1.11e-011.00e+000.9645101046
GO:0005070SH3/SH2 adaptor activity1.13e-011.00e+003.0581149
GO:0045111intermediate filament cytoskeleton1.13e-011.00e+003.0581149
GO:0001948glycoprotein binding1.16e-011.00e+003.0291250
GO:0035690cellular response to drug1.16e-011.00e+003.0291350
GO:0007030Golgi organization1.16e-011.00e+003.0291350
GO:0003684damaged DNA binding1.18e-011.00e+003.0001251
GO:0090263positive regulation of canonical Wnt signaling pathway1.18e-011.00e+003.0001151
GO:0030900forebrain development1.18e-011.00e+003.0001151
GO:0045732positive regulation of protein catabolic process1.18e-011.00e+003.0001151
GO:0008202steroid metabolic process1.20e-011.00e+002.9721152
GO:0006952defense response1.22e-011.00e+002.9451153
GO:0030175filopodium1.22e-011.00e+002.9451253
GO:0003725double-stranded RNA binding1.24e-011.00e+002.9181254
GO:0009612response to mechanical stimulus1.24e-011.00e+002.9181154
GO:0050679positive regulation of epithelial cell proliferation1.24e-011.00e+002.9181254
GO:0097193intrinsic apoptotic signaling pathway1.26e-011.00e+002.8911255
GO:0002039p53 binding1.26e-011.00e+002.8911155
GO:0046330positive regulation of JNK cascade1.26e-011.00e+002.8911155
GO:0005654nucleoplasm1.28e-011.00e+000.8985261095
GO:0043025neuronal cell body1.28e-011.00e+001.68425254
GO:0005793endoplasmic reticulum-Golgi intermediate compartment1.31e-011.00e+002.8401157
GO:0000723telomere maintenance1.35e-011.00e+002.7901259
GO:0048471perinuclear region of cytoplasm1.36e-011.00e+001.22739523
GO:0006281DNA repair1.36e-011.00e+001.62825264
GO:0010976positive regulation of neuron projection development1.37e-011.00e+002.7661260
GO:0033138positive regulation of peptidyl-serine phosphorylation1.39e-011.00e+002.7421161
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.41e-011.00e+002.7181162
GO:0000151ubiquitin ligase complex1.43e-011.00e+002.6951163
GO:0005901caveola1.43e-011.00e+002.6951163
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process1.43e-011.00e+002.6951263
GO:0005975carbohydrate metabolic process1.45e-011.00e+001.57423274
GO:0032869cellular response to insulin stimulus1.46e-011.00e+002.6731264
GO:0016491oxidoreductase activity1.48e-011.00e+002.6501165
GO:0071260cellular response to mechanical stimulus1.50e-011.00e+002.6281366
GO:0030141secretory granule1.52e-011.00e+002.6061267
GO:0003697single-stranded DNA binding1.56e-011.00e+002.5641469
GO:0035264multicellular organism growth1.58e-011.00e+002.5431170
GO:0042393histone binding1.60e-011.00e+002.5231171
GO:0001503ossification1.60e-011.00e+002.5231271
GO:0055086nucleobase-containing small molecule metabolic process1.64e-011.00e+002.4831273
GO:0042826histone deacetylase binding1.66e-011.00e+002.4631174
GO:0043234protein complex1.67e-011.00e+001.44429300
GO:0007265Ras protein signal transduction1.68e-011.00e+002.4441375
GO:0051897positive regulation of protein kinase B signaling1.68e-011.00e+002.4441175
GO:0009791post-embryonic development1.68e-011.00e+002.4441175
GO:0060070canonical Wnt signaling pathway1.68e-011.00e+002.4441275
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding1.68e-011.00e+002.4441175
GO:0044325ion channel binding1.73e-011.00e+002.4061377
GO:0001822kidney development1.77e-011.00e+002.3691279
GO:0031902late endosome membrane1.79e-011.00e+002.3511180
GO:0045177apical part of cell1.83e-011.00e+002.3151182
GO:0001726ruffle1.83e-011.00e+002.3151182
GO:0004713protein tyrosine kinase activity1.83e-011.00e+002.3151182
GO:0030336negative regulation of cell migration1.85e-011.00e+002.2971283
GO:0005929cilium1.87e-011.00e+002.2801284
GO:0005179hormone activity1.87e-011.00e+002.2801184
GO:0007411axon guidance1.91e-011.00e+001.31923327
GO:0043231intracellular membrane-bounded organelle1.95e-011.00e+001.29723332
GO:0090090negative regulation of canonical Wnt signaling pathway1.95e-011.00e+002.2131388
GO:0042593glucose homeostasis1.97e-011.00e+002.1971189
GO:0003682chromatin binding1.97e-011.00e+001.28924334
GO:0005777peroxisome1.99e-011.00e+002.1811190
GO:0005813centrosome2.02e-011.00e+001.26729339
GO:0016337single organismal cell-cell adhesion2.03e-011.00e+002.1491292
GO:0006928cellular component movement2.03e-011.00e+002.1491492
GO:0005200structural constituent of cytoskeleton2.05e-011.00e+002.1331693
GO:0005770late endosome2.07e-011.00e+002.1181194
GO:0005178integrin binding2.12e-011.00e+002.0731197
GO:0005794Golgi apparatus2.13e-011.00e+000.91338650
GO:0014069postsynaptic density2.30e-011.00e+001.94513106
GO:0030496midbody2.35e-011.00e+001.90414109
GO:0070374positive regulation of ERK1 and ERK2 cascade2.37e-011.00e+001.89111110
GO:0050900leukocyte migration2.39e-011.00e+001.87811111
GO:0020037heme binding2.39e-011.00e+001.87811111
GO:0015630microtubule cytoskeleton2.41e-011.00e+001.86514112
GO:0005819spindle2.45e-011.00e+001.84014114
GO:0005886plasma membrane2.50e-011.00e+000.3749242834
GO:0032496response to lipopolysaccharide2.60e-011.00e+001.74211122
GO:0051056regulation of small GTPase mediated signal transduction2.61e-011.00e+001.73013123
GO:0000139Golgi membrane2.64e-011.00e+001.00027408
GO:0030036actin cytoskeleton organization2.72e-011.00e+001.66113129
GO:0030027lamellipodium2.74e-011.00e+001.65013130
GO:0046983protein dimerization activity2.76e-011.00e+001.63913131
GO:0018108peptidyl-tyrosine phosphorylation2.79e-011.00e+001.61711133
GO:0005911cell-cell junction2.95e-011.00e+001.52312142
GO:0008286insulin receptor signaling pathway2.99e-011.00e+001.50314144
GO:0007596blood coagulation3.15e-011.00e+000.81525464
GO:0046777protein autophosphorylation3.23e-011.00e+001.36911158
GO:0005516calmodulin binding3.29e-011.00e+001.33313162
GO:0045893positive regulation of transcription, DNA-templated3.36e-011.00e+000.74528487
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding3.39e-011.00e+001.28014168
GO:0042802identical protein binding3.40e-011.00e+000.73324491
GO:0006351transcription, DNA-templated3.47e-011.00e+000.3645171585
GO:0004672protein kinase activity3.55e-011.00e+001.19714178
GO:0019904protein domain specific binding3.60e-011.00e+001.17313181
GO:0055085transmembrane transport3.60e-011.00e+000.66723514
GO:0005764lysosome3.62e-011.00e+001.16512182
GO:0003924GTPase activity3.94e-011.00e+001.00716203
GO:0030168platelet activation3.97e-011.00e+000.99314205
GO:0004871signal transducer activity4.13e-011.00e+000.91811216
GO:0006184GTP catabolic process4.19e-011.00e+000.89116220
GO:0016874ligase activity4.25e-011.00e+000.86512224
GO:0030425dendrite4.47e-011.00e+000.76613240
GO:0004842ubiquitin-protein transferase activity4.69e-011.00e+000.67313256
GO:0005874microtubule4.72e-011.00e+000.66113258
GO:0005102receptor binding4.85e-011.00e+000.60612268
GO:0000166nucleotide binding4.90e-011.00e+000.58512272
GO:0007283spermatogenesis4.95e-011.00e+000.56412276
GO:0042493response to drug5.10e-011.00e+000.50312288
GO:0007264small GTPase mediated signal transduction5.12e-011.00e+000.49317290
GO:0005743mitochondrial inner membrane5.24e-011.00e+000.44411300
GO:0005856cytoskeleton5.37e-011.00e+000.39216311
GO:0004674protein serine/threonine kinase activity5.38e-011.00e+000.38716312
GO:0035556intracellular signal transduction5.44e-011.00e+000.36415317
GO:0030154cell differentiation5.53e-011.00e+000.32813325
GO:0003700sequence-specific DNA binding transcription factor activity5.53e-011.00e+000.12629748
GO:0005525GTP binding5.56e-011.00e+000.31516328
GO:0008283cell proliferation5.60e-011.00e+000.30214331
GO:0007275multicellular organismal development5.74e-011.00e+000.24612344
GO:0015031protein transport5.88e-011.00e+000.19314357
GO:0008285negative regulation of cell proliferation5.98e-011.00e+000.15313367
GO:0007155cell adhesion6.15e-011.00e+000.08813384
GO:0044281small molecule metabolic process6.25e-011.00e+00-0.0813161295
GO:0045892negative regulation of transcription, DNA-templated6.52e-011.00e+00-0.05512424
GO:0006366transcription from RNA polymerase II promoter6.52e-011.00e+00-0.05913425
GO:0005524ATP binding6.56e-011.00e+00-0.1463191354
GO:0007165signal transduction6.85e-011.00e+00-0.21927950
GO:0006468protein phosphorylation6.87e-011.00e+00-0.19516467
GO:0055114oxidation-reduction process6.98e-011.00e+00-0.23712481
GO:0046872metal ion binding7.09e-011.00e+00-0.2593141465
GO:0006355regulation of transcription, DNA-templated7.63e-011.00e+00-0.4362101104
GO:0005783endoplasmic reticulum7.82e-011.00e+00-0.58016610
GO:0042803protein homodimerization activity7.86e-011.00e+00-0.59714617
GO:0003677DNA binding8.55e-011.00e+00-0.7272141351
GO:0005615extracellular space9.23e-011.00e+00-1.308131010
GO:0008270zinc ion binding9.33e-011.00e+00-1.387171067