reg-snw-27130

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.707	1.89e-24	5.18e-04	8.42e-04

tai-screen-luciferase-reg-snw-27130 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
PRIM2	5558	3	-3.507	5.269	67	-	-	-
SPDL1	54908	1	-3.376	4.707	31	-	Yes	Yes
[ INVS ]	27130	1	1.950	4.707	29	TF	-	-
CUL4B	8450	6	-2.809	5.269	142	TF	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes
RPS19	6223	2	-4.701	4.752	31	-	Yes	-

Interactions (6)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
INVS	27130	SPDL1	54908	pd	>	reg.ITFP.txt: no annot
PRIM2	5558	CUL4B	8450	pd	<	reg.ITFP.txt: no annot
CUL4B	8450	INVS	27130	pd	<>	reg.ITFP.txt: no annot
RPS19	6223	INVS	27130	pd	<	reg.ITFP.txt: no annot
CKAP5	9793	SPDL1	54908	pd	>	reg.ITFP.txt: no annot
COPA	1314	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot

Related GO terms (104)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000922	spindle pole	9.81e-04	1.00e+00	5.359	2	3	68
GO:0000278	mitotic cell cycle	1.05e-03	1.00e+00	3.736	3	9	314
GO:1990077	primosome complex	1.43e-03	1.00e+00	9.446	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.43e-03	1.00e+00	9.446	1	1	2
GO:0060265	positive regulation of respiratory burst involved in inflammatory response	1.43e-03	1.00e+00	9.446	1	1	2
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	2.15e-03	1.00e+00	8.861	1	1	3
GO:0006269	DNA replication, synthesis of RNA primer	2.15e-03	1.00e+00	8.861	1	1	3
GO:0003896	DNA primase activity	2.15e-03	1.00e+00	8.861	1	1	3
GO:0009991	response to extracellular stimulus	2.15e-03	1.00e+00	8.861	1	1	3
GO:0050658	RNA transport	2.86e-03	1.00e+00	8.446	1	1	4
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.86e-03	1.00e+00	8.446	1	1	4
GO:0031577	spindle checkpoint	2.86e-03	1.00e+00	8.446	1	1	4
GO:0007000	nucleolus organization	2.86e-03	1.00e+00	8.446	1	2	4
GO:0030157	pancreatic juice secretion	2.86e-03	1.00e+00	8.446	1	1	4
GO:0060971	embryonic heart tube left/right pattern formation	2.86e-03	1.00e+00	8.446	1	1	4
GO:0030490	maturation of SSU-rRNA	2.86e-03	1.00e+00	8.446	1	2	4
GO:0043515	kinetochore binding	2.86e-03	1.00e+00	8.446	1	1	4
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000930	gamma-tubulin complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0000028	ribosomal small subunit assembly	3.58e-03	1.00e+00	8.124	1	3	5
GO:0000940	condensed chromosome outer kinetochore	4.29e-03	1.00e+00	7.861	1	1	6
GO:0070914	UV-damage excision repair	4.29e-03	1.00e+00	7.861	1	1	6
GO:0034501	protein localization to kinetochore	5.01e-03	1.00e+00	7.639	1	1	7
GO:0030126	COPI vesicle coat	5.01e-03	1.00e+00	7.639	1	1	7
GO:0035518	histone H2A monoubiquitination	5.01e-03	1.00e+00	7.639	1	1	7
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	5.72e-03	1.00e+00	7.446	1	1	8
GO:0016020	membrane	5.97e-03	1.00e+00	2.209	4	25	1207
GO:0007051	spindle organization	7.15e-03	1.00e+00	7.124	1	1	10
GO:0051272	positive regulation of cellular component movement	7.86e-03	1.00e+00	6.987	1	1	11
GO:0007080	mitotic metaphase plate congression	7.86e-03	1.00e+00	6.987	1	1	11
GO:0042274	ribosomal small subunit biogenesis	7.86e-03	1.00e+00	6.987	1	3	11
GO:0000132	establishment of mitotic spindle orientation	8.57e-03	1.00e+00	6.861	1	2	12
GO:0051297	centrosome organization	8.57e-03	1.00e+00	6.861	1	1	12
GO:0048205	COPI coating of Golgi vesicle	8.57e-03	1.00e+00	6.861	1	1	12
GO:0035371	microtubule plus-end	9.28e-03	1.00e+00	6.746	1	1	13
GO:0017134	fibroblast growth factor binding	9.28e-03	1.00e+00	6.746	1	2	13
GO:0002548	monocyte chemotaxis	1.00e-02	1.00e+00	6.639	1	1	14
GO:0031016	pancreas development	1.14e-02	1.00e+00	6.446	1	1	16
GO:0006270	DNA replication initiation	1.21e-02	1.00e+00	6.359	1	1	17
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.21e-02	1.00e+00	6.359	1	1	17
GO:0032201	telomere maintenance via semi-conservative replication	1.43e-02	1.00e+00	6.124	1	1	20
GO:0051539	4 iron, 4 sulfur cluster binding	1.50e-02	1.00e+00	6.054	1	1	21
GO:0000722	telomere maintenance via recombination	1.57e-02	1.00e+00	5.987	1	1	22
GO:0051262	protein tetramerization	1.64e-02	1.00e+00	5.922	1	1	23
GO:0006271	DNA strand elongation involved in DNA replication	2.06e-02	1.00e+00	5.588	1	1	29
GO:0022627	cytosolic small ribosomal subunit	2.13e-02	1.00e+00	5.539	1	6	30
GO:0030218	erythrocyte differentiation	2.34e-02	1.00e+00	5.402	1	2	33
GO:0045732	positive regulation of protein catabolic process	2.41e-02	1.00e+00	5.359	1	1	34
GO:0005829	cytosol	2.45e-02	1.00e+00	1.643	4	33	1787
GO:0005840	ribosome	2.83e-02	1.00e+00	5.124	1	3	40
GO:0003684	damaged DNA binding	2.90e-02	1.00e+00	5.088	1	1	41
GO:0005929	cilium	3.32e-02	1.00e+00	4.891	1	1	47
GO:0000723	telomere maintenance	3.32e-02	1.00e+00	4.891	1	1	47
GO:0009791	post-embryonic development	3.67e-02	1.00e+00	4.746	1	1	52
GO:0001822	kidney development	3.67e-02	1.00e+00	4.746	1	2	52
GO:0090090	negative regulation of canonical Wnt signaling pathway	4.15e-02	1.00e+00	4.563	1	3	59
GO:0005179	hormone activity	4.22e-02	1.00e+00	4.539	1	1	60
GO:0019083	viral transcription	4.29e-02	1.00e+00	4.515	1	7	61
GO:0006415	translational termination	4.43e-02	1.00e+00	4.469	1	7	63
GO:0006364	rRNA processing	4.71e-02	1.00e+00	4.380	1	5	67
GO:0006414	translational elongation	4.84e-02	1.00e+00	4.338	1	7	69
GO:0015630	microtubule cytoskeleton	5.26e-02	1.00e+00	4.217	1	2	75
GO:0005815	microtubule organizing center	5.39e-02	1.00e+00	4.179	1	2	77
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	5.39e-02	1.00e+00	4.179	1	7	77
GO:0019058	viral life cycle	5.46e-02	1.00e+00	4.161	1	8	78
GO:0005819	spindle	5.60e-02	1.00e+00	4.124	1	2	80
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.87e-02	1.00e+00	4.054	1	7	84
GO:0016055	Wnt signaling pathway	6.07e-02	1.00e+00	4.003	1	2	87
GO:0006886	intracellular protein transport	6.21e-02	1.00e+00	3.970	1	1	89
GO:0061024	membrane organization	6.21e-02	1.00e+00	3.970	1	3	89
GO:0006511	ubiquitin-dependent protein catabolic process	6.41e-02	1.00e+00	3.922	1	1	92
GO:0000086	G2/M transition of mitotic cell cycle	6.75e-02	1.00e+00	3.846	1	3	97
GO:0006413	translational initiation	6.89e-02	1.00e+00	3.817	1	12	99
GO:0005516	calmodulin binding	6.89e-02	1.00e+00	3.817	1	2	99
GO:0005198	structural molecule activity	7.02e-02	1.00e+00	3.788	1	1	101
GO:0003735	structural constituent of ribosome	7.56e-02	1.00e+00	3.678	1	8	109
GO:0007049	cell cycle	7.96e-02	1.00e+00	3.601	1	2	115
GO:0000082	G1/S transition of mitotic cell cycle	8.63e-02	1.00e+00	3.480	1	6	125
GO:0005737	cytoplasm	9.00e-02	1.00e+00	1.084	4	39	2633
GO:0031625	ubiquitin protein ligase binding	9.49e-02	1.00e+00	3.338	1	2	138
GO:0070062	extracellular vesicular exosome	9.77e-02	1.00e+00	1.351	3	28	1641
GO:0005874	microtubule	1.11e-01	1.00e+00	3.097	1	2	163
GO:0007067	mitotic nuclear division	1.12e-01	1.00e+00	3.080	1	5	165
GO:0016071	mRNA metabolic process	1.16e-01	1.00e+00	3.037	1	11	170
GO:0005515	protein binding	1.19e-01	1.00e+00	0.758	5	50	4124
GO:0006412	translation	1.21e-01	1.00e+00	2.970	1	13	178
GO:0016070	RNA metabolic process	1.27e-01	1.00e+00	2.891	1	11	188
GO:0043234	protein complex	1.41e-01	1.00e+00	2.732	1	8	210
GO:0019899	enzyme binding	1.41e-01	1.00e+00	2.732	1	3	210
GO:0005813	centrosome	1.46e-01	1.00e+00	2.684	1	6	217
GO:0019901	protein kinase binding	1.55e-01	1.00e+00	2.588	1	8	232
GO:0005925	focal adhesion	1.86e-01	1.00e+00	2.306	1	12	282
GO:0005730	nucleolus	2.14e-01	1.00e+00	1.197	2	21	1217
GO:0044267	cellular protein metabolic process	2.27e-01	1.00e+00	1.987	1	13	352
GO:0042803	protein homodimerization activity	2.69e-01	1.00e+00	1.705	1	4	428
GO:0016032	viral process	2.69e-01	1.00e+00	1.705	1	13	428
GO:0010467	gene expression	3.26e-01	1.00e+00	1.383	1	17	535
GO:0005615	extracellular space	3.83e-01	1.00e+00	1.100	1	2	651
GO:0005634	nucleus	4.27e-01	1.00e+00	0.367	3	40	3246
GO:0044822	poly(A) RNA binding	4.50e-01	1.00e+00	0.804	1	25	799
GO:0005654	nucleoplasm	4.82e-01	1.00e+00	0.671	1	16	876
GO:0046872	metal ion binding	5.05e-01	1.00e+00	0.579	1	10	934
GO:0003677	DNA binding	5.10e-01	1.00e+00	0.559	1	12	947
GO:0005886	plasma membrane	7.57e-01	1.00e+00	-0.355	1	13	1784

Tai-Luciferase

reg-snw-27130

Statistics

Genes (7)

Interactions (6)

Related GO terms (104)