Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
int-snw-51741 | tai-screen-luciferase | 6.174 | 2.67e-126 | 1.32e-06 | 4.54e-03 | 24 | 19 |
reg-snw-1665 | tai-screen-luciferase | 4.688 | 3.16e-24 | 5.65e-04 | 9.13e-04 | 5 | 2 |
Gene Symbol | Entrez Gene ID | Frequency | tai-screen-luciferase gene score | Best subnetwork score | Degree | List-Gonzales GI | Tai-Hits |
---|---|---|---|---|---|---|---|
MAPK8 | 5599 | 28 | -4.403 | 6.468 | 153 | - | - |
COPA | 1314 | 48 | -9.395 | 5.672 | 340 | Yes | Yes |
RNF20 | 56254 | 28 | -4.564 | 6.174 | 18 | - | - |
CAPRIN1 | 4076 | 14 | -2.226 | 4.688 | 42 | - | - |
CUL4B | 8450 | 21 | -2.809 | 5.269 | 142 | - | - |
HSF1 | 3297 | 46 | -4.179 | 5.027 | 209 | - | Yes |
RPS24 | 6229 | 46 | -7.034 | 8.389 | 217 | Yes | - |
TCERG1 | 10915 | 28 | -3.808 | 6.174 | 58 | Yes | - |
SRC | 6714 | 28 | -2.806 | 6.174 | 419 | Yes | - |
RPS9 | 6203 | 45 | -7.127 | 7.555 | 140 | Yes | - |
DHX15 | 1665 | 2 | -1.795 | 4.688 | 37 | - | - |
COPB2 | 9276 | 48 | -13.168 | 9.063 | 41 | Yes | Yes |
CKAP5 | 9793 | 46 | -7.214 | 5.672 | 130 | Yes | Yes |
RPS4X | 6191 | 44 | -6.747 | 7.555 | 263 | Yes | - |
COPZ1 | 22818 | 48 | -8.301 | 9.063 | 13 | Yes | Yes |
RPS15A | 6210 | 36 | -5.413 | 7.555 | 177 | Yes | - |
CDC42 | 998 | 44 | -6.960 | 4.707 | 276 | Yes | Yes |
WWOX | 51741 | 28 | -2.448 | 6.174 | 38 | - | - |
RPS27A | 6233 | 45 | -5.631 | 8.389 | 344 | Yes | - |
RPS11 | 6205 | 44 | -6.588 | 7.555 | 175 | Yes | - |
RPS6 | 6194 | 44 | -5.603 | 8.046 | 217 | Yes | - |
NFKBIB | 4793 | 28 | -3.978 | 6.174 | 78 | - | - |
UBB | 7314 | 30 | -4.289 | 6.428 | 147 | - | - |
RPS26 | 6231 | 43 | -7.478 | 8.046 | 60 | Yes | - |
ARCN1 | 372 | 48 | -8.232 | 9.063 | 118 | Yes | Yes |
COPB1 | 1315 | 39 | -6.221 | 9.063 | 118 | Yes | Yes |
RPS13 | 6207 | 43 | -6.589 | 7.555 | 174 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
CDC42 | 998 | RPS27A | 6233 | pp | -- | int.I2D: SOURAV_MAPK_HIGH |
ARCN1 | 372 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG |
RPS11 | 6205 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast |
TCERG1 | 10915 | WWOX | 51741 | pp | -- | int.I2D: BioGrid, MINT, Pawson1; int.Mint: MI:0915(physical association) |
RPS6 | 6194 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS11 | 6205 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
SRC | 6714 | CKAP5 | 9793 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RPS6 | 6194 | RPS26 | 6231 | pp | -- | int.I2D: YeastLow |
CDC42 | 998 | UBB | 7314 | pp | -- | int.I2D: SOURAV_MAPK_HIGH |
NFKBIB | 4793 | UBB | 7314 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RPS9 | 6203 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium |
DHX15 | 1665 | RPS9 | 6203 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
RPS9 | 6203 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS9 | 6203 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS9 | 6203 | pp | -- | int.I2D: BioGrid_Yeast |
DHX15 | 1665 | RPS4X | 6191 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
UBB | 7314 | WWOX | 51741 | pp | -- | int.I2D: BCI, HPRD; int.HPRD: in vivo |
UBB | 7314 | RNF20 | 56254 | pp | -- | int.Intact: MI:0220(ubiquitination reaction); int.I2D: IntAct |
CAPRIN1 | 4076 | CKAP5 | 9793 | pd | < | reg.ITFP.txt: no annot |
RPS11 | 6205 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
SRC | 6714 | WWOX | 51741 | pp | -- | int.I2D: HPRD; int.HPRD: in vitro, in vivo |
DHX15 | 1665 | CAPRIN1 | 4076 | pd | > | reg.ITFP.txt: no annot |
RPS27A | 6233 | UBB | 7314 | pp | -- | int.I2D: BIND |
RPS4X | 6191 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS4X | 6191 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG |
CAPRIN1 | 4076 | CUL4B | 8450 | pd | < | reg.ITFP.txt: no annot |
RPS6 | 6194 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
RPS13 | 6207 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
RPS6 | 6194 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
COPA | 1314 | COPB1 | 1315 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh |
DHX15 | 1665 | RPS13 | 6207 | pp | -- | int.I2D: IntAct_Yeast, BioGrid_Yeast |
HSF1 | 3297 | MAPK8 | 5599 | pp | -- | int.I2D: HPRD, INNATEDB; int.HPRD: in vitro, in vivo |
COPA | 1314 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium |
COPA | 1314 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo |
COPB1 | 1315 | COPZ1 | 22818 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association) |
COPA | 1314 | CAPRIN1 | 4076 | pd | > | reg.ITFP.txt: no annot |
RPS4X | 6191 | RPS13 | 6207 | pp | -- | int.I2D: BioGrid_Yeast |
RPS15A | 6210 | RPS24 | 6229 | pp | -- | int.I2D: BioGrid_Yeast |
DHX15 | 1665 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
RPS13 | 6207 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast |
DHX15 | 1665 | RPS15A | 6210 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
COPA | 1314 | CUL4B | 8450 | pd | <> | reg.ITFP.txt: no annot |
COPB1 | 1315 | COPB2 | 9276 | pp | -- | int.I2D: BioGrid |
ARCN1 | 372 | COPB1 | 1315 | pp | -- | int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo |
RPS9 | 6203 | RPS11 | 6205 | pp | -- | int.I2D: BioGrid_Yeast |
ARCN1 | 372 | COPA | 1314 | pp | -- | int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo |
RPS4X | 6191 | RPS6 | 6194 | pp | -- | int.I2D: BioGrid_Yeast |
COPA | 1314 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
MAPK8 | 5599 | WWOX | 51741 | pp | -- | int.I2D: MINT, HPRD; int.Mint: MI:0915(physical association); int.HPRD: in vivo, yeast 2-hybrid |
RPS15A | 6210 | RPS27A | 6233 | pp | -- | int.I2D: YeastLow |
ARCN1 | 372 | COPB2 | 9276 | pp | -- | int.I2D: HPRD, BCI; int.HPRD: in vivo |
RPS24 | 6229 | RPS27A | 6233 | pp | -- | int.I2D: YeastMedium |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0022627 | cytosolic small ribosomal subunit | 4.27e-18 | 6.96e-14 | 7.124 | 9 | 21 | 39 |
GO:0019058 | viral life cycle | 1.54e-15 | 2.52e-11 | 5.716 | 10 | 25 | 115 |
GO:0019083 | viral transcription | 5.04e-15 | 8.22e-11 | 6.070 | 9 | 22 | 81 |
GO:0006415 | translational termination | 9.84e-15 | 1.61e-10 | 5.967 | 9 | 22 | 87 |
GO:0006414 | translational elongation | 1.84e-14 | 3.00e-10 | 5.870 | 9 | 22 | 93 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 5.18e-14 | 8.46e-10 | 5.709 | 9 | 22 | 104 |
GO:0005829 | cytosol | 6.79e-14 | 1.11e-09 | 2.376 | 22 | 74 | 2562 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.21e-13 | 1.98e-09 | 5.577 | 9 | 22 | 114 |
GO:0006413 | translational initiation | 4.34e-13 | 7.09e-09 | 5.376 | 9 | 27 | 131 |
GO:0003735 | structural constituent of ribosome | 8.51e-13 | 1.39e-08 | 5.270 | 9 | 24 | 141 |
GO:0016071 | mRNA metabolic process | 1.28e-12 | 2.08e-08 | 4.761 | 10 | 29 | 223 |
GO:0016070 | RNA metabolic process | 3.54e-12 | 5.77e-08 | 4.613 | 10 | 29 | 247 |
GO:0048205 | COPI coating of Golgi vesicle | 1.07e-11 | 1.74e-07 | 7.861 | 5 | 6 | 13 |
GO:0030126 | COPI vesicle coat | 1.07e-11 | 1.74e-07 | 7.861 | 5 | 6 | 13 |
GO:0016032 | viral process | 1.69e-11 | 2.75e-07 | 3.748 | 12 | 37 | 540 |
GO:0015935 | small ribosomal subunit | 5.11e-11 | 8.34e-07 | 7.474 | 5 | 9 | 17 |
GO:0061024 | membrane organization | 6.50e-11 | 1.06e-06 | 5.050 | 8 | 11 | 146 |
GO:0006412 | translation | 8.54e-11 | 1.39e-06 | 4.533 | 9 | 29 | 235 |
GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER | 4.35e-10 | 7.10e-06 | 6.918 | 5 | 6 | 25 |
GO:0044822 | poly(A) RNA binding | 3.56e-09 | 5.81e-05 | 2.866 | 13 | 42 | 1078 |
GO:0016020 | membrane | 1.29e-08 | 2.11e-04 | 2.377 | 15 | 48 | 1746 |
GO:0010467 | gene expression | 5.61e-08 | 9.16e-04 | 3.176 | 10 | 36 | 669 |
GO:0044267 | cellular protein metabolic process | 5.82e-08 | 9.49e-04 | 3.458 | 9 | 29 | 495 |
GO:0005840 | ribosome | 2.54e-06 | 4.15e-02 | 5.357 | 4 | 10 | 59 |
GO:0006891 | intra-Golgi vesicle-mediated transport | 2.70e-06 | 4.41e-02 | 6.737 | 3 | 3 | 17 |
GO:0034166 | toll-like receptor 10 signaling pathway | 3.75e-06 | 6.13e-02 | 5.217 | 4 | 5 | 65 |
GO:0034146 | toll-like receptor 5 signaling pathway | 3.75e-06 | 6.13e-02 | 5.217 | 4 | 5 | 65 |
GO:0038123 | toll-like receptor TLR1:TLR2 signaling pathway | 5.35e-06 | 8.73e-02 | 5.090 | 4 | 5 | 71 |
GO:0038124 | toll-like receptor TLR6:TLR2 signaling pathway | 5.35e-06 | 8.73e-02 | 5.090 | 4 | 5 | 71 |
GO:0034162 | toll-like receptor 9 signaling pathway | 5.66e-06 | 9.23e-02 | 5.070 | 4 | 5 | 72 |
GO:0034134 | toll-like receptor 2 signaling pathway | 5.98e-06 | 9.76e-02 | 5.050 | 4 | 5 | 73 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 6.09e-06 | 9.94e-02 | 6.365 | 3 | 5 | 22 |
GO:0035666 | TRIF-dependent toll-like receptor signaling pathway | 7.02e-06 | 1.15e-01 | 4.992 | 4 | 5 | 76 |
GO:0002756 | MyD88-independent toll-like receptor signaling pathway | 7.79e-06 | 1.27e-01 | 4.954 | 4 | 5 | 78 |
GO:0006886 | intracellular protein transport | 8.44e-06 | 1.38e-01 | 4.127 | 5 | 6 | 173 |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | 8.62e-06 | 1.41e-01 | 4.918 | 4 | 5 | 80 |
GO:0034138 | toll-like receptor 3 signaling pathway | 8.62e-06 | 1.41e-01 | 4.918 | 4 | 5 | 80 |
GO:0019843 | rRNA binding | 1.15e-05 | 1.88e-01 | 6.070 | 3 | 4 | 27 |
GO:0034142 | toll-like receptor 4 signaling pathway | 1.78e-05 | 2.90e-01 | 4.655 | 4 | 5 | 96 |
GO:0033119 | negative regulation of RNA splicing | 2.63e-05 | 4.29e-01 | 7.918 | 2 | 2 | 5 |
GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway | 2.78e-05 | 4.54e-01 | 5.655 | 3 | 3 | 36 |
GO:0002224 | toll-like receptor signaling pathway | 2.93e-05 | 4.79e-01 | 4.471 | 4 | 5 | 109 |
GO:0043065 | positive regulation of apoptotic process | 7.67e-05 | 1.00e+00 | 3.463 | 5 | 6 | 274 |
GO:0007254 | JNK cascade | 7.97e-05 | 1.00e+00 | 5.152 | 3 | 3 | 51 |
GO:0051403 | stress-activated MAPK cascade | 9.47e-05 | 1.00e+00 | 5.070 | 3 | 4 | 54 |
GO:0032481 | positive regulation of type I interferon production | 1.36e-04 | 1.00e+00 | 4.894 | 3 | 3 | 61 |
GO:0042274 | ribosomal small subunit biogenesis | 1.72e-04 | 1.00e+00 | 6.655 | 2 | 6 | 12 |
GO:0019082 | viral protein processing | 1.72e-04 | 1.00e+00 | 6.655 | 2 | 2 | 12 |
GO:0032479 | regulation of type I interferon production | 2.03e-04 | 1.00e+00 | 6.539 | 2 | 2 | 13 |
GO:0007173 | epidermal growth factor receptor signaling pathway | 2.58e-04 | 1.00e+00 | 3.662 | 4 | 5 | 191 |
GO:0005925 | focal adhesion | 3.12e-04 | 1.00e+00 | 3.030 | 5 | 23 | 370 |
GO:0070062 | extracellular vesicular exosome | 3.15e-04 | 1.00e+00 | 1.528 | 12 | 51 | 2516 |
GO:0075733 | intracellular transport of virus | 3.53e-04 | 1.00e+00 | 6.152 | 2 | 3 | 17 |
GO:0019068 | virion assembly | 3.53e-04 | 1.00e+00 | 6.152 | 2 | 2 | 17 |
GO:0045087 | innate immune response | 4.24e-04 | 1.00e+00 | 2.558 | 6 | 11 | 616 |
GO:0071456 | cellular response to hypoxia | 5.53e-04 | 1.00e+00 | 4.210 | 3 | 3 | 98 |
GO:0007220 | Notch receptor processing | 5.97e-04 | 1.00e+00 | 5.780 | 2 | 2 | 22 |
GO:0043066 | negative regulation of apoptotic process | 6.40e-04 | 1.00e+00 | 2.803 | 5 | 14 | 433 |
GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway | 7.72e-04 | 1.00e+00 | 5.596 | 2 | 2 | 25 |
GO:0005844 | polysome | 7.72e-04 | 1.00e+00 | 5.596 | 2 | 2 | 25 |
GO:0005978 | glycogen biosynthetic process | 8.36e-04 | 1.00e+00 | 5.539 | 2 | 2 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 8.36e-04 | 1.00e+00 | 5.539 | 2 | 2 | 26 |
GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 8.36e-04 | 1.00e+00 | 5.539 | 2 | 2 | 26 |
GO:0030529 | ribonucleoprotein complex | 8.59e-04 | 1.00e+00 | 3.992 | 3 | 8 | 114 |
GO:0097190 | apoptotic signaling pathway | 9.04e-04 | 1.00e+00 | 3.967 | 3 | 3 | 116 |
GO:0000209 | protein polyubiquitination | 9.04e-04 | 1.00e+00 | 3.967 | 3 | 7 | 116 |
GO:0048011 | neurotrophin TRK receptor signaling pathway | 9.92e-04 | 1.00e+00 | 3.147 | 4 | 5 | 273 |
GO:0005730 | nucleolus | 1.08e-03 | 1.00e+00 | 1.692 | 9 | 36 | 1684 |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 1.12e-03 | 1.00e+00 | 3.859 | 3 | 3 | 125 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 1.26e-03 | 1.00e+00 | 3.802 | 3 | 4 | 130 |
GO:0032480 | negative regulation of type I interferon production | 1.27e-03 | 1.00e+00 | 5.240 | 2 | 2 | 32 |
GO:0000086 | G2/M transition of mitotic cell cycle | 1.46e-03 | 1.00e+00 | 3.726 | 3 | 6 | 137 |
GO:0034332 | adherens junction organization | 1.60e-03 | 1.00e+00 | 5.070 | 2 | 4 | 36 |
GO:2001286 | regulation of caveolin-mediated endocytosis | 1.65e-03 | 1.00e+00 | 9.240 | 1 | 1 | 1 |
GO:0022605 | oogenesis stage | 1.65e-03 | 1.00e+00 | 9.240 | 1 | 1 | 1 |
GO:0071393 | cellular response to progesterone stimulus | 1.65e-03 | 1.00e+00 | 9.240 | 1 | 1 | 1 |
GO:0021691 | cerebellar Purkinje cell layer maturation | 1.65e-03 | 1.00e+00 | 9.240 | 1 | 1 | 1 |
GO:0005737 | cytoplasm | 1.87e-03 | 1.00e+00 | 1.090 | 14 | 65 | 3976 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.89e-03 | 1.00e+00 | 3.596 | 3 | 11 | 150 |
GO:0005515 | protein binding | 2.02e-03 | 1.00e+00 | 0.829 | 18 | 87 | 6127 |
GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 2.08e-03 | 1.00e+00 | 4.882 | 2 | 4 | 41 |
GO:0005198 | structural molecule activity | 2.24e-03 | 1.00e+00 | 3.512 | 3 | 5 | 159 |
GO:0008543 | fibroblast growth factor receptor signaling pathway | 2.24e-03 | 1.00e+00 | 3.512 | 3 | 3 | 159 |
GO:0035872 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | 2.28e-03 | 1.00e+00 | 4.813 | 2 | 2 | 43 |
GO:0043005 | neuron projection | 2.32e-03 | 1.00e+00 | 3.494 | 3 | 6 | 161 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 2.75e-03 | 1.00e+00 | 3.407 | 3 | 3 | 171 |
GO:0071338 | positive regulation of hair follicle cell proliferation | 3.31e-03 | 1.00e+00 | 8.240 | 1 | 1 | 2 |
GO:0060661 | submandibular salivary gland formation | 3.31e-03 | 1.00e+00 | 8.240 | 1 | 1 | 2 |
GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator | 3.31e-03 | 1.00e+00 | 8.240 | 1 | 1 | 2 |
GO:0010632 | regulation of epithelial cell migration | 3.31e-03 | 1.00e+00 | 8.240 | 1 | 1 | 2 |
GO:0090135 | actin filament branching | 3.31e-03 | 1.00e+00 | 8.240 | 1 | 1 | 2 |
GO:0030666 | endocytic vesicle membrane | 3.58e-03 | 1.00e+00 | 4.485 | 2 | 2 | 54 |
GO:0016197 | endosomal transport | 4.11e-03 | 1.00e+00 | 4.382 | 2 | 3 | 58 |
GO:0051683 | establishment of Golgi localization | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 2 | 3 |
GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0003161 | cardiac conduction system development | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0033146 | regulation of intracellular estrogen receptor signaling pathway | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0090045 | positive regulation of deacetylase activity | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0035033 | histone deacetylase regulator activity | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:2000017 | positive regulation of determination of dorsal identity | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0004705 | JUN kinase activity | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0071008 | U2-type post-mRNA release spliceosomal complex | 4.96e-03 | 1.00e+00 | 7.655 | 1 | 1 | 3 |
GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 4.99e-03 | 1.00e+00 | 4.240 | 2 | 2 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.14e-03 | 1.00e+00 | 4.217 | 2 | 6 | 65 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 5.14e-03 | 1.00e+00 | 4.217 | 2 | 6 | 65 |
GO:0031295 | T cell costimulation | 5.45e-03 | 1.00e+00 | 4.173 | 2 | 3 | 67 |
GO:0018105 | peptidyl-serine phosphorylation | 5.77e-03 | 1.00e+00 | 4.131 | 2 | 5 | 69 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.94e-03 | 1.00e+00 | 4.110 | 2 | 8 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 6.44e-03 | 1.00e+00 | 4.050 | 2 | 6 | 73 |
GO:0003729 | mRNA binding | 6.44e-03 | 1.00e+00 | 4.050 | 2 | 3 | 73 |
GO:0007258 | JUN phosphorylation | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0034191 | apolipoprotein A-I receptor binding | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0048664 | neuron fate determination | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0033503 | HULC complex | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0032463 | negative regulation of protein homooligomerization | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0051902 | negative regulation of mitochondrial depolarization | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0031062 | positive regulation of histone methylation | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0031063 | regulation of histone deacetylation | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0060684 | epithelial-mesenchymal cell signaling | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0070851 | growth factor receptor binding | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0051835 | positive regulation of synapse structural plasticity | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0033625 | positive regulation of integrin activation | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0090231 | regulation of spindle checkpoint | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 1 | 4 |
GO:0072384 | organelle transport along microtubule | 6.60e-03 | 1.00e+00 | 7.240 | 1 | 2 | 4 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 6.62e-03 | 1.00e+00 | 4.030 | 2 | 8 | 74 |
GO:0003713 | transcription coactivator activity | 7.00e-03 | 1.00e+00 | 2.924 | 3 | 6 | 239 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 7.14e-03 | 1.00e+00 | 3.973 | 2 | 4 | 77 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 7.14e-03 | 1.00e+00 | 3.973 | 2 | 6 | 77 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 7.51e-03 | 1.00e+00 | 3.936 | 2 | 8 | 79 |
GO:0071222 | cellular response to lipopolysaccharide | 7.88e-03 | 1.00e+00 | 3.900 | 2 | 4 | 81 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:2000641 | regulation of early endosome to late endosome transport | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:0036336 | dendritic cell migration | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:0035088 | establishment or maintenance of apical/basal cell polarity | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:0051385 | response to mineralocorticoid | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 3 | 5 |
GO:0097300 | programmed necrotic cell death | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:0031256 | leading edge membrane | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:0071803 | positive regulation of podosome assembly | 8.25e-03 | 1.00e+00 | 6.918 | 1 | 1 | 5 |
GO:0050852 | T cell receptor signaling pathway | 9.24e-03 | 1.00e+00 | 3.780 | 2 | 2 | 88 |
GO:0000187 | activation of MAPK activity | 9.65e-03 | 1.00e+00 | 3.748 | 2 | 3 | 90 |
GO:0050847 | progesterone receptor signaling pathway | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 1 | 6 |
GO:0007143 | female meiotic division | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 1 | 6 |
GO:0002309 | T cell proliferation involved in immune response | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 1 | 6 |
GO:0045182 | translation regulator activity | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 2 | 6 |
GO:0045056 | transcytosis | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 1 | 6 |
GO:0060789 | hair follicle placode formation | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 1 | 6 |
GO:0048554 | positive regulation of metalloenzyme activity | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 1 | 6 |
GO:0006924 | activation-induced cell death of T cells | 9.89e-03 | 1.00e+00 | 6.655 | 1 | 2 | 6 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.05e-02 | 1.00e+00 | 3.685 | 2 | 7 | 94 |
GO:0001649 | osteoblast differentiation | 1.07e-02 | 1.00e+00 | 3.670 | 2 | 3 | 95 |
GO:0006364 | rRNA processing | 1.09e-02 | 1.00e+00 | 3.655 | 2 | 8 | 96 |
GO:0050658 | RNA transport | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0007097 | nuclear migration | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 2 | 7 |
GO:0003334 | keratinocyte development | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0051988 | regulation of attachment of spindle microtubules to kinetochore | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0070914 | UV-damage excision repair | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0000028 | ribosomal small subunit assembly | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 3 | 7 |
GO:0010447 | response to acidic pH | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0034101 | erythrocyte homeostasis | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0010907 | positive regulation of glucose metabolic process | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0030157 | pancreatic juice secretion | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0060136 | embryonic process involved in female pregnancy | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0000930 | gamma-tubulin complex | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0043497 | regulation of protein heterodimerization activity | 1.15e-02 | 1.00e+00 | 6.432 | 1 | 1 | 7 |
GO:0043114 | regulation of vascular permeability | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 8 |
GO:0045124 | regulation of bone resorption | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 8 |
GO:0051489 | regulation of filopodium assembly | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 8 |
GO:0033523 | histone H2B ubiquitination | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 8 |
GO:0061003 | positive regulation of dendritic spine morphogenesis | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 8 |
GO:0007172 | signal complex assembly | 1.32e-02 | 1.00e+00 | 6.240 | 1 | 1 | 8 |
GO:0090136 | epithelial cell-cell adhesion | 1.48e-02 | 1.00e+00 | 6.070 | 1 | 2 | 9 |
GO:0047497 | mitochondrion transport along microtubule | 1.48e-02 | 1.00e+00 | 6.070 | 1 | 1 | 9 |
GO:0071732 | cellular response to nitric oxide | 1.48e-02 | 1.00e+00 | 6.070 | 1 | 1 | 9 |
GO:0046628 | positive regulation of insulin receptor signaling pathway | 1.48e-02 | 1.00e+00 | 6.070 | 1 | 1 | 9 |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1.52e-02 | 1.00e+00 | 2.037 | 4 | 9 | 589 |
GO:0006006 | glucose metabolic process | 1.64e-02 | 1.00e+00 | 3.345 | 2 | 4 | 119 |
GO:0031274 | positive regulation of pseudopodium assembly | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 2 | 10 |
GO:0003724 | RNA helicase activity | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 10 |
GO:0022407 | regulation of cell-cell adhesion | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 10 |
GO:0005798 | Golgi-associated vesicle | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 10 |
GO:0060047 | heart contraction | 1.64e-02 | 1.00e+00 | 5.918 | 1 | 1 | 10 |
GO:0007219 | Notch signaling pathway | 1.80e-02 | 1.00e+00 | 3.274 | 2 | 4 | 125 |
GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity | 1.81e-02 | 1.00e+00 | 5.780 | 1 | 1 | 11 |
GO:0060065 | uterus development | 1.81e-02 | 1.00e+00 | 5.780 | 1 | 1 | 11 |
GO:0051895 | negative regulation of focal adhesion assembly | 1.81e-02 | 1.00e+00 | 5.780 | 1 | 1 | 11 |
GO:0045120 | pronucleus | 1.81e-02 | 1.00e+00 | 5.780 | 1 | 1 | 11 |
GO:0010390 | histone monoubiquitination | 1.81e-02 | 1.00e+00 | 5.780 | 1 | 1 | 11 |
GO:0035518 | histone H2A monoubiquitination | 1.81e-02 | 1.00e+00 | 5.780 | 1 | 2 | 11 |
GO:2000573 | positive regulation of DNA biosynthetic process | 1.81e-02 | 1.00e+00 | 5.780 | 1 | 2 | 11 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.86e-02 | 1.00e+00 | 3.251 | 2 | 3 | 127 |
GO:0061136 | regulation of proteasomal protein catabolic process | 1.97e-02 | 1.00e+00 | 5.655 | 1 | 1 | 12 |
GO:0007051 | spindle organization | 1.97e-02 | 1.00e+00 | 5.655 | 1 | 1 | 12 |
GO:0043149 | stress fiber assembly | 1.97e-02 | 1.00e+00 | 5.655 | 1 | 2 | 12 |
GO:1901214 | regulation of neuron death | 1.97e-02 | 1.00e+00 | 5.655 | 1 | 1 | 12 |
GO:0009615 | response to virus | 2.00e-02 | 1.00e+00 | 3.195 | 2 | 4 | 132 |
GO:0031929 | TOR signaling | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 13 |
GO:0071398 | cellular response to fatty acid | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 2 | 13 |
GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 13 |
GO:0060444 | branching involved in mammary gland duct morphogenesis | 2.13e-02 | 1.00e+00 | 5.539 | 1 | 1 | 13 |
GO:0035371 | microtubule plus-end | 2.29e-02 | 1.00e+00 | 5.432 | 1 | 1 | 14 |
GO:0031333 | negative regulation of protein complex assembly | 2.29e-02 | 1.00e+00 | 5.432 | 1 | 1 | 14 |
GO:0031996 | thioesterase binding | 2.29e-02 | 1.00e+00 | 5.432 | 1 | 1 | 14 |
GO:0050662 | coenzyme binding | 2.29e-02 | 1.00e+00 | 5.432 | 1 | 1 | 14 |
GO:0048821 | erythrocyte development | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 2 | 15 |
GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 15 |
GO:0048477 | oogenesis | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 15 |
GO:0030131 | clathrin adaptor complex | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 15 |
GO:0030225 | macrophage differentiation | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 1 | 15 |
GO:0031369 | translation initiation factor binding | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 2 | 15 |
GO:0051233 | spindle midzone | 2.45e-02 | 1.00e+00 | 5.333 | 1 | 2 | 15 |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling | 2.47e-02 | 1.00e+00 | 3.030 | 2 | 3 | 148 |
GO:0010628 | positive regulation of gene expression | 2.50e-02 | 1.00e+00 | 3.020 | 2 | 4 | 149 |
GO:0042981 | regulation of apoptotic process | 2.57e-02 | 1.00e+00 | 3.001 | 2 | 7 | 151 |
GO:0042176 | regulation of protein catabolic process | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 4 | 16 |
GO:0014911 | positive regulation of smooth muscle cell migration | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 16 |
GO:0008284 | positive regulation of cell proliferation | 2.62e-02 | 1.00e+00 | 2.210 | 3 | 7 | 392 |
GO:2000811 | negative regulation of anoikis | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 16 |
GO:0048037 | cofactor binding | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 16 |
GO:0050775 | positive regulation of dendrite morphogenesis | 2.62e-02 | 1.00e+00 | 5.240 | 1 | 1 | 16 |
GO:0000278 | mitotic cell cycle | 2.73e-02 | 1.00e+00 | 2.188 | 3 | 16 | 398 |
GO:0010008 | endosome membrane | 2.76e-02 | 1.00e+00 | 2.945 | 2 | 2 | 157 |
GO:0030742 | GTP-dependent protein binding | 2.78e-02 | 1.00e+00 | 5.152 | 1 | 1 | 17 |
GO:0070064 | proline-rich region binding | 2.94e-02 | 1.00e+00 | 5.070 | 1 | 1 | 18 |
GO:0031954 | positive regulation of protein autophosphorylation | 2.94e-02 | 1.00e+00 | 5.070 | 1 | 1 | 18 |
GO:0090316 | positive regulation of intracellular protein transport | 2.94e-02 | 1.00e+00 | 5.070 | 1 | 1 | 18 |
GO:0034220 | ion transmembrane transport | 3.09e-02 | 1.00e+00 | 2.856 | 2 | 2 | 167 |
GO:0007088 | regulation of mitosis | 3.10e-02 | 1.00e+00 | 4.992 | 1 | 1 | 19 |
GO:0045453 | bone resorption | 3.10e-02 | 1.00e+00 | 4.992 | 1 | 1 | 19 |
GO:0031667 | response to nutrient levels | 3.10e-02 | 1.00e+00 | 4.992 | 1 | 1 | 19 |
GO:0005634 | nucleus | 3.21e-02 | 1.00e+00 | 0.703 | 13 | 66 | 4828 |
GO:0032148 | activation of protein kinase B activity | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 20 |
GO:0051090 | regulation of sequence-specific DNA binding transcription factor activity | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 2 | 20 |
GO:0043473 | pigmentation | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 2 | 20 |
GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 1 | 20 |
GO:0043393 | regulation of protein binding | 3.26e-02 | 1.00e+00 | 4.918 | 1 | 2 | 20 |
GO:0046847 | filopodium assembly | 3.42e-02 | 1.00e+00 | 4.847 | 1 | 1 | 21 |
GO:0007369 | gastrulation | 3.42e-02 | 1.00e+00 | 4.847 | 1 | 1 | 21 |
GO:0051881 | regulation of mitochondrial membrane potential | 3.42e-02 | 1.00e+00 | 4.847 | 1 | 1 | 21 |
GO:0005689 | U12-type spliceosomal complex | 3.42e-02 | 1.00e+00 | 4.847 | 1 | 2 | 21 |
GO:0007049 | cell cycle | 3.44e-02 | 1.00e+00 | 2.772 | 2 | 4 | 177 |
GO:0031625 | ubiquitin protein ligase binding | 3.54e-02 | 1.00e+00 | 2.748 | 2 | 4 | 180 |
GO:0001106 | RNA polymerase II transcription corepressor activity | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 1 | 22 |
GO:0031435 | mitogen-activated protein kinase kinase kinase binding | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 1 | 22 |
GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 1 | 22 |
GO:0046686 | response to cadmium ion | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 1 | 22 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 3.69e-02 | 1.00e+00 | 2.716 | 2 | 5 | 184 |
GO:0001892 | embryonic placenta development | 3.74e-02 | 1.00e+00 | 4.716 | 1 | 1 | 23 |
GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading | 3.74e-02 | 1.00e+00 | 4.716 | 1 | 1 | 23 |
GO:0051297 | centrosome organization | 3.74e-02 | 1.00e+00 | 4.716 | 1 | 2 | 23 |
GO:0045787 | positive regulation of cell cycle | 3.74e-02 | 1.00e+00 | 4.716 | 1 | 2 | 23 |
GO:0002040 | sprouting angiogenesis | 3.74e-02 | 1.00e+00 | 4.716 | 1 | 1 | 23 |
GO:0051017 | actin filament bundle assembly | 3.74e-02 | 1.00e+00 | 4.716 | 1 | 1 | 23 |
GO:0007163 | establishment or maintenance of cell polarity | 3.90e-02 | 1.00e+00 | 4.655 | 1 | 2 | 24 |
GO:0051602 | response to electrical stimulus | 3.90e-02 | 1.00e+00 | 4.655 | 1 | 1 | 24 |
GO:0050715 | positive regulation of cytokine secretion | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 25 |
GO:0048705 | skeletal system morphogenesis | 4.06e-02 | 1.00e+00 | 4.596 | 1 | 1 | 25 |
GO:1900740 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | 4.22e-02 | 1.00e+00 | 4.539 | 1 | 1 | 26 |
GO:0045859 | regulation of protein kinase activity | 4.22e-02 | 1.00e+00 | 4.539 | 1 | 1 | 26 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 4.28e-02 | 1.00e+00 | 1.576 | 4 | 11 | 811 |
GO:0031424 | keratinization | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 1 | 27 |
GO:0051149 | positive regulation of muscle cell differentiation | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 2 | 27 |
GO:0032720 | negative regulation of tumor necrosis factor production | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 1 | 27 |
GO:0001103 | RNA polymerase II repressing transcription factor binding | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 1 | 27 |
GO:0030331 | estrogen receptor binding | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 1 | 27 |
GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 1 | 27 |
GO:0031069 | hair follicle morphogenesis | 4.38e-02 | 1.00e+00 | 4.485 | 1 | 1 | 27 |
GO:0032467 | positive regulation of cytokinesis | 4.53e-02 | 1.00e+00 | 4.432 | 1 | 1 | 28 |
GO:0034605 | cellular response to heat | 4.69e-02 | 1.00e+00 | 4.382 | 1 | 1 | 29 |
GO:0072686 | mitotic spindle | 4.69e-02 | 1.00e+00 | 4.382 | 1 | 1 | 29 |
GO:0042169 | SH2 domain binding | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 1 | 30 |
GO:0031647 | regulation of protein stability | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 1 | 30 |
GO:0040018 | positive regulation of multicellular organism growth | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 1 | 30 |
GO:0046875 | ephrin receptor binding | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 2 | 30 |
GO:0010494 | cytoplasmic stress granule | 4.85e-02 | 1.00e+00 | 4.333 | 1 | 2 | 30 |
GO:0070555 | response to interleukin-1 | 5.01e-02 | 1.00e+00 | 4.285 | 1 | 1 | 31 |
GO:0007093 | mitotic cell cycle checkpoint | 5.01e-02 | 1.00e+00 | 4.285 | 1 | 2 | 31 |
GO:0051219 | phosphoprotein binding | 5.17e-02 | 1.00e+00 | 4.240 | 1 | 4 | 32 |
GO:0032091 | negative regulation of protein binding | 5.32e-02 | 1.00e+00 | 4.195 | 1 | 1 | 33 |
GO:0033077 | T cell differentiation in thymus | 5.32e-02 | 1.00e+00 | 4.195 | 1 | 1 | 33 |
GO:0005158 | insulin receptor binding | 5.32e-02 | 1.00e+00 | 4.195 | 1 | 2 | 33 |
GO:0048812 | neuron projection morphogenesis | 5.32e-02 | 1.00e+00 | 4.195 | 1 | 1 | 33 |
GO:0042692 | muscle cell differentiation | 5.48e-02 | 1.00e+00 | 4.152 | 1 | 2 | 34 |
GO:0001890 | placenta development | 5.48e-02 | 1.00e+00 | 4.152 | 1 | 1 | 34 |
GO:0019221 | cytokine-mediated signaling pathway | 5.51e-02 | 1.00e+00 | 2.394 | 2 | 5 | 230 |
GO:0007067 | mitotic nuclear division | 5.55e-02 | 1.00e+00 | 2.388 | 2 | 7 | 231 |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 5.64e-02 | 1.00e+00 | 4.110 | 1 | 1 | 35 |
GO:0071560 | cellular response to transforming growth factor beta stimulus | 5.79e-02 | 1.00e+00 | 4.070 | 1 | 1 | 36 |
GO:0030178 | negative regulation of Wnt signaling pathway | 5.79e-02 | 1.00e+00 | 4.070 | 1 | 1 | 36 |
GO:0030425 | dendrite | 5.94e-02 | 1.00e+00 | 2.333 | 2 | 3 | 240 |
GO:0016301 | kinase activity | 5.95e-02 | 1.00e+00 | 4.030 | 1 | 2 | 37 |
GO:0018107 | peptidyl-threonine phosphorylation | 5.95e-02 | 1.00e+00 | 4.030 | 1 | 1 | 37 |
GO:0032880 | regulation of protein localization | 5.95e-02 | 1.00e+00 | 4.030 | 1 | 1 | 37 |
GO:0097191 | extrinsic apoptotic signaling pathway | 6.10e-02 | 1.00e+00 | 3.992 | 1 | 3 | 38 |
GO:0045740 | positive regulation of DNA replication | 6.10e-02 | 1.00e+00 | 3.992 | 1 | 1 | 38 |
GO:0008026 | ATP-dependent helicase activity | 6.26e-02 | 1.00e+00 | 3.954 | 1 | 2 | 39 |
GO:0042542 | response to hydrogen peroxide | 6.42e-02 | 1.00e+00 | 3.918 | 1 | 1 | 40 |
GO:0043025 | neuronal cell body | 6.56e-02 | 1.00e+00 | 2.251 | 2 | 5 | 254 |
GO:0045785 | positive regulation of cell adhesion | 6.57e-02 | 1.00e+00 | 3.882 | 1 | 1 | 41 |
GO:0070301 | cellular response to hydrogen peroxide | 6.57e-02 | 1.00e+00 | 3.882 | 1 | 1 | 41 |
GO:0017148 | negative regulation of translation | 6.57e-02 | 1.00e+00 | 3.882 | 1 | 1 | 41 |
GO:0006915 | apoptotic process | 6.69e-02 | 1.00e+00 | 1.667 | 3 | 9 | 571 |
GO:0005902 | microvillus | 6.73e-02 | 1.00e+00 | 3.847 | 1 | 1 | 42 |
GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 6.73e-02 | 1.00e+00 | 3.847 | 1 | 1 | 42 |
GO:0006281 | DNA repair | 7.02e-02 | 1.00e+00 | 2.195 | 2 | 5 | 264 |
GO:0034613 | cellular protein localization | 7.03e-02 | 1.00e+00 | 3.780 | 1 | 2 | 44 |
GO:0005080 | protein kinase C binding | 7.03e-02 | 1.00e+00 | 3.780 | 1 | 1 | 44 |
GO:0009411 | response to UV | 7.19e-02 | 1.00e+00 | 3.748 | 1 | 2 | 45 |
GO:0021762 | substantia nigra development | 7.34e-02 | 1.00e+00 | 3.716 | 1 | 2 | 46 |
GO:0044297 | cell body | 7.34e-02 | 1.00e+00 | 3.716 | 1 | 1 | 46 |
GO:0043525 | positive regulation of neuron apoptotic process | 7.34e-02 | 1.00e+00 | 3.716 | 1 | 2 | 46 |
GO:0045727 | positive regulation of translation | 7.34e-02 | 1.00e+00 | 3.716 | 1 | 1 | 46 |
GO:0005975 | carbohydrate metabolic process | 7.49e-02 | 1.00e+00 | 2.142 | 2 | 3 | 274 |
GO:0043406 | positive regulation of MAP kinase activity | 7.50e-02 | 1.00e+00 | 3.685 | 1 | 1 | 47 |
GO:0008344 | adult locomotory behavior | 7.50e-02 | 1.00e+00 | 3.685 | 1 | 2 | 47 |
GO:0006950 | response to stress | 7.65e-02 | 1.00e+00 | 3.655 | 1 | 1 | 48 |
GO:0005070 | SH3/SH2 adaptor activity | 7.80e-02 | 1.00e+00 | 3.625 | 1 | 1 | 49 |
GO:0007030 | Golgi organization | 7.96e-02 | 1.00e+00 | 3.596 | 1 | 3 | 50 |
GO:0090263 | positive regulation of canonical Wnt signaling pathway | 8.11e-02 | 1.00e+00 | 3.567 | 1 | 1 | 51 |
GO:0030900 | forebrain development | 8.11e-02 | 1.00e+00 | 3.567 | 1 | 1 | 51 |
GO:0003684 | damaged DNA binding | 8.11e-02 | 1.00e+00 | 3.567 | 1 | 2 | 51 |
GO:0045732 | positive regulation of protein catabolic process | 8.11e-02 | 1.00e+00 | 3.567 | 1 | 1 | 51 |
GO:0019899 | enzyme binding | 8.16e-02 | 1.00e+00 | 2.070 | 2 | 5 | 288 |
GO:0008202 | steroid metabolic process | 8.26e-02 | 1.00e+00 | 3.539 | 1 | 1 | 52 |
GO:0006952 | defense response | 8.41e-02 | 1.00e+00 | 3.512 | 1 | 1 | 53 |
GO:0030175 | filopodium | 8.41e-02 | 1.00e+00 | 3.512 | 1 | 2 | 53 |
GO:0003725 | double-stranded RNA binding | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 2 | 54 |
GO:0009612 | response to mechanical stimulus | 8.57e-02 | 1.00e+00 | 3.485 | 1 | 1 | 54 |
GO:0097193 | intrinsic apoptotic signaling pathway | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 2 | 55 |
GO:0002039 | p53 binding | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 1 | 55 |
GO:0046330 | positive regulation of JNK cascade | 8.72e-02 | 1.00e+00 | 3.458 | 1 | 1 | 55 |
GO:0043234 | protein complex | 8.75e-02 | 1.00e+00 | 2.011 | 2 | 9 | 300 |
GO:0000932 | cytoplasmic mRNA processing body | 8.87e-02 | 1.00e+00 | 3.432 | 1 | 1 | 56 |
GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment | 9.02e-02 | 1.00e+00 | 3.407 | 1 | 1 | 57 |
GO:0005794 | Golgi apparatus | 9.07e-02 | 1.00e+00 | 1.480 | 3 | 8 | 650 |
GO:0005739 | mitochondrion | 9.11e-02 | 1.00e+00 | 1.209 | 4 | 10 | 1046 |
GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 9.62e-02 | 1.00e+00 | 3.309 | 1 | 1 | 61 |
GO:0019901 | protein kinase binding | 9.76e-02 | 1.00e+00 | 1.918 | 2 | 9 | 320 |
GO:0001078 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | 9.77e-02 | 1.00e+00 | 3.285 | 1 | 1 | 62 |
GO:0000151 | ubiquitin ligase complex | 9.92e-02 | 1.00e+00 | 3.262 | 1 | 1 | 63 |
GO:0005901 | caveola | 9.92e-02 | 1.00e+00 | 3.262 | 1 | 1 | 63 |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | 9.92e-02 | 1.00e+00 | 3.262 | 1 | 2 | 63 |
GO:0006417 | regulation of translation | 9.92e-02 | 1.00e+00 | 3.262 | 1 | 4 | 63 |
GO:0032869 | cellular response to insulin stimulus | 1.01e-01 | 1.00e+00 | 3.240 | 1 | 2 | 64 |
GO:0007411 | axon guidance | 1.01e-01 | 1.00e+00 | 1.886 | 2 | 3 | 327 |
GO:0016491 | oxidoreductase activity | 1.02e-01 | 1.00e+00 | 3.217 | 1 | 1 | 65 |
GO:0071260 | cellular response to mechanical stimulus | 1.04e-01 | 1.00e+00 | 3.195 | 1 | 3 | 66 |
GO:0043231 | intracellular membrane-bounded organelle | 1.04e-01 | 1.00e+00 | 1.865 | 2 | 3 | 332 |
GO:0003682 | chromatin binding | 1.05e-01 | 1.00e+00 | 1.856 | 2 | 4 | 334 |
GO:0030141 | secretory granule | 1.05e-01 | 1.00e+00 | 3.173 | 1 | 2 | 67 |
GO:0035264 | multicellular organism growth | 1.10e-01 | 1.00e+00 | 3.110 | 1 | 1 | 70 |
GO:0042393 | histone binding | 1.11e-01 | 1.00e+00 | 3.090 | 1 | 1 | 71 |
GO:0001503 | ossification | 1.11e-01 | 1.00e+00 | 3.090 | 1 | 2 | 71 |
GO:0042826 | histone deacetylase binding | 1.16e-01 | 1.00e+00 | 3.030 | 1 | 1 | 74 |
GO:0003723 | RNA binding | 1.16e-01 | 1.00e+00 | 1.768 | 2 | 10 | 355 |
GO:0060070 | canonical Wnt signaling pathway | 1.17e-01 | 1.00e+00 | 3.011 | 1 | 2 | 75 |
GO:0007265 | Ras protein signal transduction | 1.17e-01 | 1.00e+00 | 3.011 | 1 | 3 | 75 |
GO:0051897 | positive regulation of protein kinase B signaling | 1.17e-01 | 1.00e+00 | 3.011 | 1 | 1 | 75 |
GO:0044325 | ion channel binding | 1.20e-01 | 1.00e+00 | 2.973 | 1 | 3 | 77 |
GO:0007229 | integrin-mediated signaling pathway | 1.21e-01 | 1.00e+00 | 2.954 | 1 | 2 | 78 |
GO:0010629 | negative regulation of gene expression | 1.24e-01 | 1.00e+00 | 2.918 | 1 | 2 | 80 |
GO:0045177 | apical part of cell | 1.27e-01 | 1.00e+00 | 2.882 | 1 | 1 | 82 |
GO:0004713 | protein tyrosine kinase activity | 1.27e-01 | 1.00e+00 | 2.882 | 1 | 1 | 82 |
GO:0030336 | negative regulation of cell migration | 1.29e-01 | 1.00e+00 | 2.865 | 1 | 2 | 83 |
GO:0005179 | hormone activity | 1.30e-01 | 1.00e+00 | 2.847 | 1 | 1 | 84 |
GO:0042593 | glucose homeostasis | 1.37e-01 | 1.00e+00 | 2.764 | 1 | 1 | 89 |
GO:0000922 | spindle pole | 1.40e-01 | 1.00e+00 | 2.732 | 1 | 5 | 91 |
GO:0016337 | single organismal cell-cell adhesion | 1.42e-01 | 1.00e+00 | 2.716 | 1 | 2 | 92 |
GO:0005770 | late endosome | 1.45e-01 | 1.00e+00 | 2.685 | 1 | 1 | 94 |
GO:0000139 | Golgi membrane | 1.46e-01 | 1.00e+00 | 1.567 | 2 | 7 | 408 |
GO:0005178 | integrin binding | 1.49e-01 | 1.00e+00 | 2.640 | 1 | 1 | 97 |
GO:0014069 | postsynaptic density | 1.61e-01 | 1.00e+00 | 2.512 | 1 | 3 | 106 |
GO:0030496 | midbody | 1.66e-01 | 1.00e+00 | 2.471 | 1 | 4 | 109 |
GO:0005815 | microtubule organizing center | 1.67e-01 | 1.00e+00 | 2.458 | 1 | 4 | 110 |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 1.67e-01 | 1.00e+00 | 2.458 | 1 | 1 | 110 |
GO:0020037 | heme binding | 1.68e-01 | 1.00e+00 | 2.445 | 1 | 1 | 111 |
GO:0050900 | leukocyte migration | 1.68e-01 | 1.00e+00 | 2.445 | 1 | 1 | 111 |
GO:0015630 | microtubule cytoskeleton | 1.70e-01 | 1.00e+00 | 2.432 | 1 | 4 | 112 |
GO:0005886 | plasma membrane | 1.76e-01 | 1.00e+00 | 0.578 | 7 | 24 | 2834 |
GO:0007596 | blood coagulation | 1.78e-01 | 1.00e+00 | 1.382 | 2 | 5 | 464 |
GO:0032496 | response to lipopolysaccharide | 1.84e-01 | 1.00e+00 | 2.309 | 1 | 1 | 122 |
GO:0051056 | regulation of small GTPase mediated signal transduction | 1.85e-01 | 1.00e+00 | 2.297 | 1 | 3 | 123 |
GO:0045893 | positive regulation of transcription, DNA-templated | 1.92e-01 | 1.00e+00 | 1.312 | 2 | 8 | 487 |
GO:0030036 | actin cytoskeleton organization | 1.93e-01 | 1.00e+00 | 2.228 | 1 | 3 | 129 |
GO:0046983 | protein dimerization activity | 1.96e-01 | 1.00e+00 | 2.206 | 1 | 3 | 131 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 1.98e-01 | 1.00e+00 | 2.184 | 1 | 1 | 133 |
GO:0055085 | transmembrane transport | 2.08e-01 | 1.00e+00 | 1.234 | 2 | 3 | 514 |
GO:0016055 | Wnt signaling pathway | 2.09e-01 | 1.00e+00 | 2.100 | 1 | 3 | 141 |
GO:0005911 | cell-cell junction | 2.10e-01 | 1.00e+00 | 2.090 | 1 | 2 | 142 |
GO:0008286 | insulin receptor signaling pathway | 2.13e-01 | 1.00e+00 | 2.070 | 1 | 4 | 144 |
GO:0046777 | protein autophosphorylation | 2.31e-01 | 1.00e+00 | 1.936 | 1 | 1 | 158 |
GO:0008022 | protein C-terminus binding | 2.35e-01 | 1.00e+00 | 1.909 | 1 | 4 | 161 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2.44e-01 | 1.00e+00 | 1.847 | 1 | 4 | 168 |
GO:0006397 | mRNA processing | 2.45e-01 | 1.00e+00 | 1.839 | 1 | 3 | 169 |
GO:0004672 | protein kinase activity | 2.56e-01 | 1.00e+00 | 1.764 | 1 | 4 | 178 |
GO:0005764 | lysosome | 2.61e-01 | 1.00e+00 | 1.732 | 1 | 2 | 182 |
GO:0006351 | transcription, DNA-templated | 2.64e-01 | 1.00e+00 | 0.609 | 4 | 17 | 1585 |
GO:0005654 | nucleoplasm | 2.70e-01 | 1.00e+00 | 0.728 | 3 | 26 | 1095 |
GO:0003924 | GTPase activity | 2.87e-01 | 1.00e+00 | 1.574 | 1 | 6 | 203 |
GO:0030168 | platelet activation | 2.89e-01 | 1.00e+00 | 1.560 | 1 | 4 | 205 |
GO:0004871 | signal transducer activity | 3.02e-01 | 1.00e+00 | 1.485 | 1 | 1 | 216 |
GO:0006184 | GTP catabolic process | 3.07e-01 | 1.00e+00 | 1.458 | 1 | 6 | 220 |
GO:0016874 | ligase activity | 3.12e-01 | 1.00e+00 | 1.432 | 1 | 2 | 224 |
GO:0008380 | RNA splicing | 3.21e-01 | 1.00e+00 | 1.382 | 1 | 5 | 232 |
GO:0004842 | ubiquitin-protein transferase activity | 3.48e-01 | 1.00e+00 | 1.240 | 1 | 3 | 256 |
GO:0005102 | receptor binding | 3.61e-01 | 1.00e+00 | 1.173 | 1 | 2 | 268 |
GO:0000166 | nucleotide binding | 3.65e-01 | 1.00e+00 | 1.152 | 1 | 2 | 272 |
GO:0007283 | spermatogenesis | 3.69e-01 | 1.00e+00 | 1.131 | 1 | 2 | 276 |
GO:0042493 | response to drug | 3.82e-01 | 1.00e+00 | 1.070 | 1 | 2 | 288 |
GO:0007264 | small GTPase mediated signal transduction | 3.84e-01 | 1.00e+00 | 1.060 | 1 | 7 | 290 |
GO:0005524 | ATP binding | 3.91e-01 | 1.00e+00 | 0.422 | 3 | 19 | 1354 |
GO:0005743 | mitochondrial inner membrane | 3.94e-01 | 1.00e+00 | 1.011 | 1 | 1 | 300 |
GO:0006200 | ATP catabolic process | 3.97e-01 | 1.00e+00 | 0.996 | 1 | 4 | 303 |
GO:0004674 | protein serine/threonine kinase activity | 4.06e-01 | 1.00e+00 | 0.954 | 1 | 6 | 312 |
GO:0035556 | intracellular signal transduction | 4.11e-01 | 1.00e+00 | 0.931 | 1 | 5 | 317 |
GO:0005525 | GTP binding | 4.22e-01 | 1.00e+00 | 0.882 | 1 | 6 | 328 |
GO:0008283 | cell proliferation | 4.25e-01 | 1.00e+00 | 0.869 | 1 | 4 | 331 |
GO:0005813 | centrosome | 4.33e-01 | 1.00e+00 | 0.834 | 1 | 9 | 339 |
GO:0007275 | multicellular organismal development | 4.38e-01 | 1.00e+00 | 0.813 | 1 | 2 | 344 |
GO:0008285 | negative regulation of cell proliferation | 4.59e-01 | 1.00e+00 | 0.720 | 1 | 3 | 367 |
GO:0007165 | signal transduction | 4.72e-01 | 1.00e+00 | 0.348 | 2 | 7 | 950 |
GO:0045892 | negative regulation of transcription, DNA-templated | 5.09e-01 | 1.00e+00 | 0.512 | 1 | 2 | 424 |
GO:0006366 | transcription from RNA polymerase II promoter | 5.10e-01 | 1.00e+00 | 0.508 | 1 | 3 | 425 |
GO:0006468 | protein phosphorylation | 5.44e-01 | 1.00e+00 | 0.372 | 1 | 6 | 467 |
GO:0055114 | oxidation-reduction process | 5.54e-01 | 1.00e+00 | 0.330 | 1 | 2 | 481 |
GO:0042802 | identical protein binding | 5.62e-01 | 1.00e+00 | 0.300 | 1 | 4 | 491 |
GO:0048471 | perinuclear region of cytoplasm | 5.85e-01 | 1.00e+00 | 0.209 | 1 | 9 | 523 |
GO:0005783 | endoplasmic reticulum | 6.43e-01 | 1.00e+00 | -0.013 | 1 | 6 | 610 |
GO:0044281 | small molecule metabolic process | 6.43e-01 | 1.00e+00 | -0.099 | 2 | 16 | 1295 |
GO:0003700 | sequence-specific DNA binding transcription factor activity | 7.19e-01 | 1.00e+00 | -0.307 | 1 | 9 | 748 |
GO:0005887 | integral component of plasma membrane | 8.06e-01 | 1.00e+00 | -0.669 | 1 | 2 | 961 |
GO:0005615 | extracellular space | 8.22e-01 | 1.00e+00 | -0.741 | 1 | 3 | 1010 |
GO:0008270 | zinc ion binding | 8.39e-01 | 1.00e+00 | -0.820 | 1 | 7 | 1067 |
GO:0006355 | regulation of transcription, DNA-templated | 8.49e-01 | 1.00e+00 | -0.869 | 1 | 10 | 1104 |
GO:0046872 | metal ion binding | 9.21e-01 | 1.00e+00 | -1.277 | 1 | 14 | 1465 |