meta-reg-snw-10097

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
int-snw-51741	tai-screen-luciferase	6.174	2.67e-126	1.32e-06	4.54e-03	24	19
reg-snw-10097	tai-screen-luciferase	4.851	3.99e-26	2.69e-04	4.60e-04	6	3

tai-screen-luciferase-meta-reg-snw-10097 subnetwork

Genes (28)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
MAPK8	5599	28	-4.403	6.468	153	-	-
COPA	1314	48	-9.395	5.672	340	Yes	Yes
RNF20	56254	28	-4.564	6.174	18	-	-
IQGAP1	8826	2	-3.777	4.851	10	-	-
CUL4B	8450	21	-2.809	5.269	142	-	-
HSF1	3297	46	-4.179	5.027	209	-	Yes
RPS24	6229	46	-7.034	8.389	217	Yes	-
TCERG1	10915	28	-3.808	6.174	58	Yes	-
SRC	6714	28	-2.806	6.174	419	Yes	-
RPS9	6203	45	-7.127	7.555	140	Yes	-
COPB2	9276	48	-13.168	9.063	41	Yes	Yes
CKAP5	9793	46	-7.214	5.672	130	Yes	Yes
RPS4X	6191	44	-6.747	7.555	263	Yes	-
COPZ1	22818	48	-8.301	9.063	13	Yes	Yes
RPS15A	6210	36	-5.413	7.555	177	Yes	-
CDC42	998	44	-6.960	4.707	276	Yes	Yes
WWOX	51741	28	-2.448	6.174	38	-	-
RPS27A	6233	45	-5.631	8.389	344	Yes	-
RPS11	6205	44	-6.588	7.555	175	Yes	-
RPS6	6194	44	-5.603	8.046	217	Yes	-
ACTR2	10097	2	-2.490	4.851	65	Yes	-
NFKBIB	4793	28	-3.978	6.174	78	-	-
UBB	7314	30	-4.289	6.428	147	-	-
RPS26	6231	43	-7.478	8.046	60	Yes	-
ARCN1	372	48	-8.232	9.063	118	Yes	Yes
COPB1	1315	39	-6.221	9.063	118	Yes	Yes
RPS13	6207	43	-6.589	7.555	174	Yes	-
CDC5L	988	34	-3.419	5.672	155	-	-

Interactions (55)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC42	998	RPS27A	6233	pp	--	int.I2D: SOURAV_MAPK_HIGH
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
RPS11	6205	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
TCERG1	10915	WWOX	51741	pp	--	int.I2D: BioGrid, MINT, Pawson1; int.Mint: MI:0915(physical association)
RPS6	6194	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
CDC5L	988	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot
RPS11	6205	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
SRC	6714	CKAP5	9793	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPS6	6194	RPS26	6231	pp	--	int.I2D: YeastLow
CDC42	998	UBB	7314	pp	--	int.I2D: SOURAV_MAPK_HIGH
NFKBIB	4793	UBB	7314	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPS9	6203	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS9	6203	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS27A	6233	ACTR2	10097	pp	--	int.I2D: YeastLow
RPS9	6203	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS9	6203	pp	--	int.I2D: BioGrid_Yeast
UBB	7314	WWOX	51741	pp	--	int.I2D: BCI, HPRD; int.HPRD: in vivo
UBB	7314	RNF20	56254	pp	--	int.Intact: MI:0220(ubiquitination reaction); int.I2D: IntAct
RPS11	6205	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	ACTR2	10097	pd	>	reg.ITFP.txt: no annot
NFKBIB	4793	IQGAP1	8826	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
SRC	6714	WWOX	51741	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
RPS27A	6233	UBB	7314	pp	--	int.I2D: BIND
IQGAP1	8826	ACTR2	10097	pd	>	reg.ITFP.txt: no annot
RPS4X	6191	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
CUL4B	8450	ACTR2	10097	pd	>	reg.ITFP.txt: no annot
RPS4X	6191	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS6	6194	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS27A	6233	pp	--	int.I2D: YeastLow
COPA	1314	COPB1	1315	pp	--	int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
HSF1	3297	MAPK8	5599	pp	--	int.I2D: HPRD, INNATEDB; int.HPRD: in vitro, in vivo
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
COPB1	1315	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association)
RPS4X	6191	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS15A	6210	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
COPA	1314	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot
COPB1	1315	COPB2	9276	pp	--	int.I2D: BioGrid
ARCN1	372	COPB1	1315	pp	--	int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo
RPS9	6203	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
CDC42	998	IQGAP1	8826	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, MINT, BCI, IntAct; int.Mint: MI:0915(physical association), MI:0407(direct interaction); int.HPRD: in vitro, in vivo
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
RPS4X	6191	RPS6	6194	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	RPS27A	6233	pp	--	int.I2D: YeastLow
MAPK8	5599	WWOX	51741	pp	--	int.I2D: MINT, HPRD; int.Mint: MI:0915(physical association); int.HPRD: in vivo, yeast 2-hybrid
RPS15A	6210	RPS27A	6233	pp	--	int.I2D: YeastLow
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
CDC5L	988	ACTR2	10097	pd	>	reg.ITFP.txt: no annot
RPS24	6229	RPS27A	6233	pp	--	int.I2D: YeastMedium

Related GO terms (477)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0022627	cytosolic small ribosomal subunit	6.28e-18	1.02e-13	7.072	9	21	39
GO:0019058	viral life cycle	2.39e-15	3.90e-11	5.664	10	25	115
GO:0019083	viral transcription	7.39e-15	1.21e-10	6.017	9	22	81
GO:0006415	translational termination	1.44e-14	2.36e-10	5.914	9	22	87
GO:0006414	translational elongation	2.69e-14	4.39e-10	5.818	9	22	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.60e-14	1.24e-09	5.657	9	22	104
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.77e-13	2.90e-09	5.524	9	22	114
GO:0005829	cytosol	2.70e-13	4.40e-09	2.323	22	74	2562
GO:0006413	translational initiation	6.36e-13	1.04e-08	5.324	9	27	131
GO:0003735	structural constituent of ribosome	1.24e-12	2.03e-08	5.217	9	24	141
GO:0016071	mRNA metabolic process	1.96e-12	3.20e-08	4.708	10	29	223
GO:0016070	RNA metabolic process	5.43e-12	8.86e-08	4.561	10	29	247
GO:0048205	COPI coating of Golgi vesicle	1.30e-11	2.12e-07	7.809	5	6	13
GO:0030126	COPI vesicle coat	1.30e-11	2.12e-07	7.809	5	6	13
GO:0016032	viral process	2.86e-11	4.67e-07	3.695	12	37	540
GO:0015935	small ribosomal subunit	6.22e-11	1.01e-06	7.422	5	9	17
GO:0061024	membrane organization	9.03e-11	1.47e-06	4.997	8	11	146
GO:0006412	translation	1.24e-10	2.03e-06	4.480	9	29	235
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	5.29e-10	8.63e-06	6.865	5	6	25
GO:0016020	membrane	2.39e-09	3.90e-05	2.417	16	48	1746
GO:0036464	cytoplasmic ribonucleoprotein granule	4.96e-08	8.10e-04	6.728	4	5	22
GO:0044822	poly(A) RNA binding	7.34e-08	1.20e-03	2.698	12	42	1078
GO:0044267	cellular protein metabolic process	8.34e-08	1.36e-03	3.406	9	29	495
GO:0010467	gene expression	8.41e-08	1.37e-03	3.123	10	36	669
GO:0005925	focal adhesion	2.28e-06	3.73e-02	3.463	7	23	370
GO:0005840	ribosome	2.96e-06	4.82e-02	5.304	4	10	59
GO:0006891	intra-Golgi vesicle-mediated transport	3.03e-06	4.94e-02	6.685	3	3	17
GO:0034166	toll-like receptor 10 signaling pathway	4.37e-06	7.12e-02	5.165	4	5	65
GO:0034146	toll-like receptor 5 signaling pathway	4.37e-06	7.12e-02	5.165	4	5	65
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	6.22e-06	1.02e-01	5.037	4	5	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	6.22e-06	1.02e-01	5.037	4	5	71
GO:0034162	toll-like receptor 9 signaling pathway	6.58e-06	1.07e-01	5.017	4	5	72
GO:0034134	toll-like receptor 2 signaling pathway	6.95e-06	1.13e-01	4.997	4	5	73
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	8.17e-06	1.33e-01	4.939	4	5	76
GO:0002756	MyD88-independent toll-like receptor signaling pathway	9.06e-06	1.48e-01	4.902	4	5	78
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.00e-05	1.64e-01	4.865	4	5	80
GO:0034138	toll-like receptor 3 signaling pathway	1.00e-05	1.64e-01	4.865	4	5	80
GO:0006886	intracellular protein transport	1.02e-05	1.66e-01	4.074	5	6	173
GO:0019843	rRNA binding	1.29e-05	2.10e-01	6.017	3	4	27
GO:0007173	epidermal growth factor receptor signaling pathway	1.64e-05	2.68e-01	3.932	5	5	191
GO:0070062	extracellular vesicular exosome	1.94e-05	3.16e-01	1.698	14	51	2516
GO:0034142	toll-like receptor 4 signaling pathway	2.07e-05	3.37e-01	4.602	4	5	96
GO:0033119	negative regulation of RNA splicing	2.83e-05	4.62e-01	7.865	2	2	5
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.11e-05	5.07e-01	5.602	3	3	36
GO:0002224	toll-like receptor signaling pathway	3.41e-05	5.56e-01	4.419	4	5	109
GO:0045087	innate immune response	6.25e-05	1.00e+00	2.728	7	11	616
GO:0007254	JNK cascade	8.91e-05	1.00e+00	5.100	3	3	51
GO:0043065	positive regulation of apoptotic process	9.21e-05	1.00e+00	3.411	5	6	274
GO:0051403	stress-activated MAPK cascade	1.06e-04	1.00e+00	5.017	3	4	54
GO:0032481	positive regulation of type I interferon production	1.52e-04	1.00e+00	4.841	3	3	61
GO:0043005	neuron projection	1.55e-04	1.00e+00	3.856	4	6	161
GO:0042274	ribosomal small subunit biogenesis	1.85e-04	1.00e+00	6.602	2	6	12
GO:0019082	viral protein processing	1.85e-04	1.00e+00	6.602	2	2	12
GO:0005737	cytoplasm	2.08e-04	1.00e+00	1.230	16	65	3976
GO:0032479	regulation of type I interferon production	2.19e-04	1.00e+00	6.487	2	2	13
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.04e-04	1.00e+00	4.505	3	4	77
GO:0005730	nucleolus	3.05e-04	1.00e+00	1.791	10	36	1684
GO:0075733	intracellular transport of virus	3.80e-04	1.00e+00	6.100	2	3	17
GO:0019068	virion assembly	3.80e-04	1.00e+00	6.100	2	2	17
GO:0071456	cellular response to hypoxia	6.17e-04	1.00e+00	4.157	3	3	98
GO:0007220	Notch receptor processing	6.42e-04	1.00e+00	5.728	2	2	22
GO:0043066	negative regulation of apoptotic process	7.62e-04	1.00e+00	2.751	5	14	433
GO:0007163	establishment or maintenance of cell polarity	7.65e-04	1.00e+00	5.602	2	2	24
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	8.31e-04	1.00e+00	5.543	2	2	25
GO:0005844	polysome	8.31e-04	1.00e+00	5.543	2	2	25
GO:0005978	glycogen biosynthetic process	8.99e-04	1.00e+00	5.487	2	2	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	8.99e-04	1.00e+00	5.487	2	2	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	8.99e-04	1.00e+00	5.487	2	2	26
GO:0030529	ribonucleoprotein complex	9.57e-04	1.00e+00	3.939	3	8	114
GO:0097190	apoptotic signaling pathway	1.01e-03	1.00e+00	3.914	3	3	116
GO:0000209	protein polyubiquitination	1.01e-03	1.00e+00	3.914	3	7	116
GO:0005515	protein binding	1.10e-03	1.00e+00	0.854	19	87	6127
GO:0048011	neurotrophin TRK receptor signaling pathway	1.14e-03	1.00e+00	3.094	4	5	273
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.25e-03	1.00e+00	3.806	3	3	125
GO:0032480	negative regulation of type I interferon production	1.36e-03	1.00e+00	5.187	2	2	32
GO:0007179	transforming growth factor beta receptor signaling pathway	1.40e-03	1.00e+00	3.750	3	4	130
GO:0000086	G2/M transition of mitotic cell cycle	1.63e-03	1.00e+00	3.674	3	6	137
GO:2001286	regulation of caveolin-mediated endocytosis	1.72e-03	1.00e+00	9.187	1	1	1
GO:0034332	adherens junction organization	1.72e-03	1.00e+00	5.017	2	4	36
GO:0022605	oogenesis stage	1.72e-03	1.00e+00	9.187	1	1	1
GO:0071393	cellular response to progesterone stimulus	1.72e-03	1.00e+00	9.187	1	1	1
GO:0021691	cerebellar Purkinje cell layer maturation	1.72e-03	1.00e+00	9.187	1	1	1
GO:0000082	G1/S transition of mitotic cell cycle	2.11e-03	1.00e+00	3.543	3	11	150
GO:0007249	I-kappaB kinase/NF-kappaB signaling	2.23e-03	1.00e+00	4.830	2	4	41
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	2.45e-03	1.00e+00	4.761	2	2	43
GO:0005198	structural molecule activity	2.49e-03	1.00e+00	3.459	3	5	159
GO:0008543	fibroblast growth factor receptor signaling pathway	2.49e-03	1.00e+00	3.459	3	3	159
GO:0038095	Fc-epsilon receptor signaling pathway	3.05e-03	1.00e+00	3.354	3	3	171
GO:0071338	positive regulation of hair follicle cell proliferation	3.43e-03	1.00e+00	8.187	1	1	2
GO:0033206	meiotic cytokinesis	3.43e-03	1.00e+00	8.187	1	1	2
GO:0071987	WD40-repeat domain binding	3.43e-03	1.00e+00	8.187	1	1	2
GO:0060661	submandibular salivary gland formation	3.43e-03	1.00e+00	8.187	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	3.43e-03	1.00e+00	8.187	1	1	2
GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	3.43e-03	1.00e+00	8.187	1	1	2
GO:0016344	meiotic chromosome movement towards spindle pole	3.43e-03	1.00e+00	8.187	1	1	2
GO:0035305	negative regulation of dephosphorylation	3.43e-03	1.00e+00	8.187	1	1	2
GO:0010632	regulation of epithelial cell migration	3.43e-03	1.00e+00	8.187	1	1	2
GO:0090135	actin filament branching	3.43e-03	1.00e+00	8.187	1	1	2
GO:0030666	endocytic vesicle membrane	3.84e-03	1.00e+00	4.432	2	2	54
GO:0016197	endosomal transport	4.42e-03	1.00e+00	4.329	2	3	58
GO:0051683	establishment of Golgi localization	5.14e-03	1.00e+00	7.602	1	2	3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	5.14e-03	1.00e+00	7.602	1	1	3
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	5.14e-03	1.00e+00	7.602	1	1	3
GO:0008356	asymmetric cell division	5.14e-03	1.00e+00	7.602	1	1	3
GO:0003161	cardiac conduction system development	5.14e-03	1.00e+00	7.602	1	1	3
GO:0051653	spindle localization	5.14e-03	1.00e+00	7.602	1	1	3
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	5.14e-03	1.00e+00	7.602	1	1	3
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	5.14e-03	1.00e+00	7.602	1	1	3
GO:0090045	positive regulation of deacetylase activity	5.14e-03	1.00e+00	7.602	1	1	3
GO:0035033	histone deacetylase regulator activity	5.14e-03	1.00e+00	7.602	1	1	3
GO:2000017	positive regulation of determination of dorsal identity	5.14e-03	1.00e+00	7.602	1	1	3
GO:0004705	JUN kinase activity	5.14e-03	1.00e+00	7.602	1	1	3
GO:0030478	actin cap	5.14e-03	1.00e+00	7.602	1	1	3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	5.36e-03	1.00e+00	4.187	2	2	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.52e-03	1.00e+00	4.165	2	6	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.52e-03	1.00e+00	4.165	2	6	65
GO:0031295	T cell costimulation	5.86e-03	1.00e+00	4.121	2	3	67
GO:0018105	peptidyl-serine phosphorylation	6.20e-03	1.00e+00	4.079	2	5	69
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.38e-03	1.00e+00	4.058	2	8	70
GO:0007258	JUN phosphorylation	6.85e-03	1.00e+00	7.187	1	1	4
GO:0034191	apolipoprotein A-I receptor binding	6.85e-03	1.00e+00	7.187	1	1	4
GO:0048664	neuron fate determination	6.85e-03	1.00e+00	7.187	1	1	4
GO:0033503	HULC complex	6.85e-03	1.00e+00	7.187	1	1	4
GO:0032463	negative regulation of protein homooligomerization	6.85e-03	1.00e+00	7.187	1	1	4
GO:0051902	negative regulation of mitochondrial depolarization	6.85e-03	1.00e+00	7.187	1	1	4
GO:0031062	positive regulation of histone methylation	6.85e-03	1.00e+00	7.187	1	1	4
GO:0031063	regulation of histone deacetylation	6.85e-03	1.00e+00	7.187	1	1	4
GO:0060684	epithelial-mesenchymal cell signaling	6.85e-03	1.00e+00	7.187	1	1	4
GO:0070851	growth factor receptor binding	6.85e-03	1.00e+00	7.187	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	6.85e-03	1.00e+00	7.187	1	1	4
GO:0033625	positive regulation of integrin activation	6.85e-03	1.00e+00	7.187	1	1	4
GO:0090231	regulation of spindle checkpoint	6.85e-03	1.00e+00	7.187	1	1	4
GO:0072384	organelle transport along microtubule	6.85e-03	1.00e+00	7.187	1	2	4
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.92e-03	1.00e+00	3.997	2	6	73
GO:0003729	mRNA binding	6.92e-03	1.00e+00	3.997	2	3	73
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.10e-03	1.00e+00	3.978	2	8	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.67e-03	1.00e+00	3.920	2	6	77
GO:0003713	transcription coactivator activity	7.75e-03	1.00e+00	2.871	3	6	239
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	8.06e-03	1.00e+00	3.883	2	8	79
GO:0071222	cellular response to lipopolysaccharide	8.46e-03	1.00e+00	3.847	2	4	81
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	8.55e-03	1.00e+00	6.865	1	1	5
GO:1990138	neuron projection extension	8.55e-03	1.00e+00	6.865	1	1	5
GO:2000641	regulation of early endosome to late endosome transport	8.55e-03	1.00e+00	6.865	1	1	5
GO:0036336	dendritic cell migration	8.55e-03	1.00e+00	6.865	1	1	5
GO:0035088	establishment or maintenance of apical/basal cell polarity	8.55e-03	1.00e+00	6.865	1	1	5
GO:0051385	response to mineralocorticoid	8.55e-03	1.00e+00	6.865	1	1	5
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	8.55e-03	1.00e+00	6.865	1	3	5
GO:0097300	programmed necrotic cell death	8.55e-03	1.00e+00	6.865	1	1	5
GO:0031256	leading edge membrane	8.55e-03	1.00e+00	6.865	1	1	5
GO:0071803	positive regulation of podosome assembly	8.55e-03	1.00e+00	6.865	1	1	5
GO:0016482	cytoplasmic transport	8.55e-03	1.00e+00	6.865	1	1	5
GO:0050852	T cell receptor signaling pathway	9.92e-03	1.00e+00	3.728	2	2	88
GO:0050847	progesterone receptor signaling pathway	1.03e-02	1.00e+00	6.602	1	1	6
GO:0007143	female meiotic division	1.03e-02	1.00e+00	6.602	1	1	6
GO:0002309	T cell proliferation involved in immune response	1.03e-02	1.00e+00	6.602	1	1	6
GO:0045182	translation regulator activity	1.03e-02	1.00e+00	6.602	1	2	6
GO:0045056	transcytosis	1.03e-02	1.00e+00	6.602	1	1	6
GO:0000974	Prp19 complex	1.03e-02	1.00e+00	6.602	1	1	6
GO:0060789	hair follicle placode formation	1.03e-02	1.00e+00	6.602	1	1	6
GO:0072015	glomerular visceral epithelial cell development	1.03e-02	1.00e+00	6.602	1	1	6
GO:0048554	positive regulation of metalloenzyme activity	1.03e-02	1.00e+00	6.602	1	1	6
GO:0006924	activation-induced cell death of T cells	1.03e-02	1.00e+00	6.602	1	2	6
GO:0000187	activation of MAPK activity	1.04e-02	1.00e+00	3.695	2	3	90
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.13e-02	1.00e+00	3.632	2	7	94
GO:0001649	osteoblast differentiation	1.15e-02	1.00e+00	3.617	2	3	95
GO:0006364	rRNA processing	1.17e-02	1.00e+00	3.602	2	8	96
GO:0050658	RNA transport	1.19e-02	1.00e+00	6.380	1	1	7
GO:0007097	nuclear migration	1.19e-02	1.00e+00	6.380	1	2	7
GO:0003334	keratinocyte development	1.19e-02	1.00e+00	6.380	1	1	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.19e-02	1.00e+00	6.380	1	1	7
GO:0070914	UV-damage excision repair	1.19e-02	1.00e+00	6.380	1	1	7
GO:0000028	ribosomal small subunit assembly	1.19e-02	1.00e+00	6.380	1	3	7
GO:0010447	response to acidic pH	1.19e-02	1.00e+00	6.380	1	1	7
GO:0034101	erythrocyte homeostasis	1.19e-02	1.00e+00	6.380	1	1	7
GO:0005885	Arp2/3 protein complex	1.19e-02	1.00e+00	6.380	1	1	7
GO:0010907	positive regulation of glucose metabolic process	1.19e-02	1.00e+00	6.380	1	1	7
GO:0030157	pancreatic juice secretion	1.19e-02	1.00e+00	6.380	1	1	7
GO:0060136	embryonic process involved in female pregnancy	1.19e-02	1.00e+00	6.380	1	1	7
GO:0000930	gamma-tubulin complex	1.19e-02	1.00e+00	6.380	1	1	7
GO:0043497	regulation of protein heterodimerization activity	1.19e-02	1.00e+00	6.380	1	1	7
GO:0043114	regulation of vascular permeability	1.36e-02	1.00e+00	6.187	1	1	8
GO:0045124	regulation of bone resorption	1.36e-02	1.00e+00	6.187	1	1	8
GO:0051489	regulation of filopodium assembly	1.36e-02	1.00e+00	6.187	1	1	8
GO:0033523	histone H2B ubiquitination	1.36e-02	1.00e+00	6.187	1	1	8
GO:0036057	slit diaphragm	1.36e-02	1.00e+00	6.187	1	1	8
GO:0007172	signal complex assembly	1.36e-02	1.00e+00	6.187	1	1	8
GO:0030496	midbody	1.49e-02	1.00e+00	3.419	2	4	109
GO:0090136	epithelial cell-cell adhesion	1.53e-02	1.00e+00	6.017	1	2	9
GO:0047497	mitochondrion transport along microtubule	1.53e-02	1.00e+00	6.017	1	1	9
GO:0071732	cellular response to nitric oxide	1.53e-02	1.00e+00	6.017	1	1	9
GO:0046628	positive regulation of insulin receptor signaling pathway	1.53e-02	1.00e+00	6.017	1	1	9
GO:0015630	microtubule cytoskeleton	1.57e-02	1.00e+00	3.380	2	4	112
GO:0031274	positive regulation of pseudopodium assembly	1.70e-02	1.00e+00	5.865	1	2	10
GO:0019901	protein kinase binding	1.70e-02	1.00e+00	2.450	3	9	320
GO:0022407	regulation of cell-cell adhesion	1.70e-02	1.00e+00	5.865	1	1	10
GO:0001817	regulation of cytokine production	1.70e-02	1.00e+00	5.865	1	1	10
GO:0005798	Golgi-associated vesicle	1.70e-02	1.00e+00	5.865	1	1	10
GO:0060047	heart contraction	1.70e-02	1.00e+00	5.865	1	1	10
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.73e-02	1.00e+00	1.985	4	9	589
GO:0006006	glucose metabolic process	1.76e-02	1.00e+00	3.292	2	4	119
GO:0005634	nucleus	1.83e-02	1.00e+00	0.757	14	66	4828
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	1.87e-02	1.00e+00	5.728	1	1	11
GO:0034314	Arp2/3 complex-mediated actin nucleation	1.87e-02	1.00e+00	5.728	1	1	11
GO:0060065	uterus development	1.87e-02	1.00e+00	5.728	1	1	11
GO:0051895	negative regulation of focal adhesion assembly	1.87e-02	1.00e+00	5.728	1	1	11
GO:0045120	pronucleus	1.87e-02	1.00e+00	5.728	1	1	11
GO:0010390	histone monoubiquitination	1.87e-02	1.00e+00	5.728	1	1	11
GO:0035518	histone H2A monoubiquitination	1.87e-02	1.00e+00	5.728	1	2	11
GO:2000573	positive regulation of DNA biosynthetic process	1.87e-02	1.00e+00	5.728	1	2	11
GO:0003682	chromatin binding	1.91e-02	1.00e+00	2.388	3	4	334
GO:0007219	Notch signaling pathway	1.93e-02	1.00e+00	3.221	2	4	125
GO:0006511	ubiquitin-dependent protein catabolic process	1.99e-02	1.00e+00	3.198	2	3	127
GO:0061136	regulation of proteasomal protein catabolic process	2.04e-02	1.00e+00	5.602	1	1	12
GO:0007051	spindle organization	2.04e-02	1.00e+00	5.602	1	1	12
GO:0043149	stress fiber assembly	2.04e-02	1.00e+00	5.602	1	2	12
GO:1901214	regulation of neuron death	2.04e-02	1.00e+00	5.602	1	1	12
GO:0009615	response to virus	2.14e-02	1.00e+00	3.143	2	4	132
GO:0031929	TOR signaling	2.21e-02	1.00e+00	5.487	1	1	13
GO:0005662	DNA replication factor A complex	2.21e-02	1.00e+00	5.487	1	1	13
GO:0071398	cellular response to fatty acid	2.21e-02	1.00e+00	5.487	1	2	13
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	2.21e-02	1.00e+00	5.487	1	1	13
GO:0060444	branching involved in mammary gland duct morphogenesis	2.21e-02	1.00e+00	5.487	1	1	13
GO:0035371	microtubule plus-end	2.38e-02	1.00e+00	5.380	1	1	14
GO:0031333	negative regulation of protein complex assembly	2.38e-02	1.00e+00	5.380	1	1	14
GO:0031996	thioesterase binding	2.38e-02	1.00e+00	5.380	1	1	14
GO:0050662	coenzyme binding	2.38e-02	1.00e+00	5.380	1	1	14
GO:0005095	GTPase inhibitor activity	2.38e-02	1.00e+00	5.380	1	1	14
GO:0043539	protein serine/threonine kinase activator activity	2.38e-02	1.00e+00	5.380	1	1	14
GO:0048821	erythrocyte development	2.54e-02	1.00e+00	5.280	1	2	15
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	2.54e-02	1.00e+00	5.280	1	1	15
GO:0048477	oogenesis	2.54e-02	1.00e+00	5.280	1	1	15
GO:0030131	clathrin adaptor complex	2.54e-02	1.00e+00	5.280	1	1	15
GO:0030225	macrophage differentiation	2.54e-02	1.00e+00	5.280	1	1	15
GO:0031369	translation initiation factor binding	2.54e-02	1.00e+00	5.280	1	2	15
GO:0051233	spindle midzone	2.54e-02	1.00e+00	5.280	1	2	15
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	2.65e-02	1.00e+00	2.978	2	3	148
GO:0010628	positive regulation of gene expression	2.68e-02	1.00e+00	2.968	2	4	149
GO:0042176	regulation of protein catabolic process	2.71e-02	1.00e+00	5.187	1	4	16
GO:0014911	positive regulation of smooth muscle cell migration	2.71e-02	1.00e+00	5.187	1	1	16
GO:2000811	negative regulation of anoikis	2.71e-02	1.00e+00	5.187	1	1	16
GO:0048037	cofactor binding	2.71e-02	1.00e+00	5.187	1	1	16
GO:0005099	Ras GTPase activator activity	2.71e-02	1.00e+00	5.187	1	1	16
GO:0042981	regulation of apoptotic process	2.75e-02	1.00e+00	2.949	2	7	151
GO:0030742	GTP-dependent protein binding	2.88e-02	1.00e+00	5.100	1	1	17
GO:0008284	positive regulation of cell proliferation	2.89e-02	1.00e+00	2.157	3	7	392
GO:0010008	endosome membrane	2.95e-02	1.00e+00	2.892	2	2	157
GO:0000278	mitotic cell cycle	3.00e-02	1.00e+00	2.135	3	16	398
GO:0070064	proline-rich region binding	3.04e-02	1.00e+00	5.017	1	1	18
GO:0031954	positive regulation of protein autophosphorylation	3.04e-02	1.00e+00	5.017	1	1	18
GO:0090316	positive regulation of intracellular protein transport	3.04e-02	1.00e+00	5.017	1	1	18
GO:0007088	regulation of mitosis	3.21e-02	1.00e+00	4.939	1	1	19
GO:0045453	bone resorption	3.21e-02	1.00e+00	4.939	1	1	19
GO:0031667	response to nutrient levels	3.21e-02	1.00e+00	4.939	1	1	19
GO:0034220	ion transmembrane transport	3.31e-02	1.00e+00	2.803	2	2	167
GO:0032148	activation of protein kinase B activity	3.38e-02	1.00e+00	4.865	1	1	20
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	3.38e-02	1.00e+00	4.865	1	2	20
GO:0043473	pigmentation	3.38e-02	1.00e+00	4.865	1	2	20
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	3.38e-02	1.00e+00	4.865	1	1	20
GO:0043393	regulation of protein binding	3.38e-02	1.00e+00	4.865	1	2	20
GO:0046847	filopodium assembly	3.54e-02	1.00e+00	4.795	1	1	21
GO:0007369	gastrulation	3.54e-02	1.00e+00	4.795	1	1	21
GO:0051881	regulation of mitochondrial membrane potential	3.54e-02	1.00e+00	4.795	1	1	21
GO:0071364	cellular response to epidermal growth factor stimulus	3.54e-02	1.00e+00	4.795	1	1	21
GO:0007049	cell cycle	3.68e-02	1.00e+00	2.719	2	4	177
GO:0001106	RNA polymerase II transcription corepressor activity	3.71e-02	1.00e+00	4.728	1	1	22
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3.71e-02	1.00e+00	4.728	1	1	22
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	3.71e-02	1.00e+00	4.728	1	1	22
GO:0046686	response to cadmium ion	3.71e-02	1.00e+00	4.728	1	1	22
GO:0031625	ubiquitin protein ligase binding	3.79e-02	1.00e+00	2.695	2	4	180
GO:0001892	embryonic placenta development	3.87e-02	1.00e+00	4.664	1	1	23
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	3.87e-02	1.00e+00	4.664	1	1	23
GO:0051297	centrosome organization	3.87e-02	1.00e+00	4.664	1	2	23
GO:0045787	positive regulation of cell cycle	3.87e-02	1.00e+00	4.664	1	2	23
GO:0002040	sprouting angiogenesis	3.87e-02	1.00e+00	4.664	1	1	23
GO:0051017	actin filament bundle assembly	3.87e-02	1.00e+00	4.664	1	1	23
GO:0015629	actin cytoskeleton	3.91e-02	1.00e+00	2.671	2	3	183
GO:0006367	transcription initiation from RNA polymerase II promoter	3.94e-02	1.00e+00	2.664	2	5	184
GO:0051602	response to electrical stimulus	4.04e-02	1.00e+00	4.602	1	1	24
GO:0050715	positive regulation of cytokine secretion	4.20e-02	1.00e+00	4.543	1	1	25
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	4.20e-02	1.00e+00	4.543	1	1	25
GO:0048705	skeletal system morphogenesis	4.20e-02	1.00e+00	4.543	1	1	25
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	4.37e-02	1.00e+00	4.487	1	1	26
GO:0071902	positive regulation of protein serine/threonine kinase activity	4.37e-02	1.00e+00	4.487	1	1	26
GO:0045859	regulation of protein kinase activity	4.37e-02	1.00e+00	4.487	1	1	26
GO:0031424	keratinization	4.53e-02	1.00e+00	4.432	1	1	27
GO:0051149	positive regulation of muscle cell differentiation	4.53e-02	1.00e+00	4.432	1	2	27
GO:0032720	negative regulation of tumor necrosis factor production	4.53e-02	1.00e+00	4.432	1	1	27
GO:0001103	RNA polymerase II repressing transcription factor binding	4.53e-02	1.00e+00	4.432	1	1	27
GO:0030331	estrogen receptor binding	4.53e-02	1.00e+00	4.432	1	1	27
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	4.53e-02	1.00e+00	4.432	1	1	27
GO:0031069	hair follicle morphogenesis	4.53e-02	1.00e+00	4.432	1	1	27
GO:0032467	positive regulation of cytokinesis	4.70e-02	1.00e+00	4.380	1	1	28
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.80e-02	1.00e+00	1.524	4	11	811
GO:0031252	cell leading edge	4.86e-02	1.00e+00	4.329	1	3	29
GO:0048365	Rac GTPase binding	4.86e-02	1.00e+00	4.329	1	1	29
GO:0034605	cellular response to heat	4.86e-02	1.00e+00	4.329	1	1	29
GO:0072686	mitotic spindle	4.86e-02	1.00e+00	4.329	1	1	29
GO:0042169	SH2 domain binding	5.03e-02	1.00e+00	4.280	1	1	30
GO:0031647	regulation of protein stability	5.03e-02	1.00e+00	4.280	1	1	30
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5.03e-02	1.00e+00	4.280	1	1	30
GO:0040018	positive regulation of multicellular organism growth	5.03e-02	1.00e+00	4.280	1	1	30
GO:0046875	ephrin receptor binding	5.03e-02	1.00e+00	4.280	1	2	30
GO:0070555	response to interleukin-1	5.19e-02	1.00e+00	4.233	1	1	31
GO:0007093	mitotic cell cycle checkpoint	5.19e-02	1.00e+00	4.233	1	2	31
GO:0032320	positive regulation of Ras GTPase activity	5.35e-02	1.00e+00	4.187	1	1	32
GO:0051219	phosphoprotein binding	5.35e-02	1.00e+00	4.187	1	4	32
GO:0032091	negative regulation of protein binding	5.51e-02	1.00e+00	4.143	1	1	33
GO:0033077	T cell differentiation in thymus	5.51e-02	1.00e+00	4.143	1	1	33
GO:0005158	insulin receptor binding	5.51e-02	1.00e+00	4.143	1	2	33
GO:0048812	neuron projection morphogenesis	5.51e-02	1.00e+00	4.143	1	1	33
GO:0042692	muscle cell differentiation	5.68e-02	1.00e+00	4.100	1	2	34
GO:0001890	placenta development	5.68e-02	1.00e+00	4.100	1	1	34
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	5.84e-02	1.00e+00	4.058	1	1	35
GO:0019221	cytokine-mediated signaling pathway	5.88e-02	1.00e+00	2.342	2	5	230
GO:0007067	mitotic nuclear division	5.93e-02	1.00e+00	2.335	2	7	231
GO:0071560	cellular response to transforming growth factor beta stimulus	6.00e-02	1.00e+00	4.017	1	1	36
GO:0030178	negative regulation of Wnt signaling pathway	6.00e-02	1.00e+00	4.017	1	1	36
GO:0016301	kinase activity	6.16e-02	1.00e+00	3.978	1	2	37
GO:0018107	peptidyl-threonine phosphorylation	6.16e-02	1.00e+00	3.978	1	1	37
GO:0032880	regulation of protein localization	6.16e-02	1.00e+00	3.978	1	1	37
GO:0071277	cellular response to calcium ion	6.16e-02	1.00e+00	3.978	1	1	37
GO:0097191	extrinsic apoptotic signaling pathway	6.32e-02	1.00e+00	3.939	1	3	38
GO:0045740	positive regulation of DNA replication	6.32e-02	1.00e+00	3.939	1	1	38
GO:0042542	response to hydrogen peroxide	6.65e-02	1.00e+00	3.865	1	1	40
GO:0045785	positive regulation of cell adhesion	6.81e-02	1.00e+00	3.830	1	1	41
GO:0070301	cellular response to hydrogen peroxide	6.81e-02	1.00e+00	3.830	1	1	41
GO:0005902	microvillus	6.97e-02	1.00e+00	3.795	1	1	42
GO:0004715	non-membrane spanning protein tyrosine kinase activity	6.97e-02	1.00e+00	3.795	1	1	42
GO:0043025	neuronal cell body	7.00e-02	1.00e+00	2.198	2	5	254
GO:0034613	cellular protein localization	7.29e-02	1.00e+00	3.728	1	2	44
GO:0005080	protein kinase C binding	7.29e-02	1.00e+00	3.728	1	1	44
GO:0006915	apoptotic process	7.31e-02	1.00e+00	1.615	3	9	571
GO:0045860	positive regulation of protein kinase activity	7.45e-02	1.00e+00	3.695	1	1	45
GO:0009411	response to UV	7.45e-02	1.00e+00	3.695	1	2	45
GO:0006281	DNA repair	7.48e-02	1.00e+00	2.143	2	5	264
GO:0021762	substantia nigra development	7.60e-02	1.00e+00	3.664	1	2	46
GO:0016328	lateral plasma membrane	7.60e-02	1.00e+00	3.664	1	3	46
GO:0044297	cell body	7.60e-02	1.00e+00	3.664	1	1	46
GO:0043525	positive regulation of neuron apoptotic process	7.60e-02	1.00e+00	3.664	1	2	46
GO:0045727	positive regulation of translation	7.60e-02	1.00e+00	3.664	1	1	46
GO:0005884	actin filament	7.60e-02	1.00e+00	3.664	1	2	46
GO:0043406	positive regulation of MAP kinase activity	7.76e-02	1.00e+00	3.632	1	1	47
GO:0008344	adult locomotory behavior	7.76e-02	1.00e+00	3.632	1	2	47
GO:0006950	response to stress	7.92e-02	1.00e+00	3.602	1	1	48
GO:0005975	carbohydrate metabolic process	7.98e-02	1.00e+00	2.089	2	3	274
GO:0005070	SH3/SH2 adaptor activity	8.08e-02	1.00e+00	3.572	1	1	49
GO:0007030	Golgi organization	8.24e-02	1.00e+00	3.543	1	3	50
GO:0090263	positive regulation of canonical Wnt signaling pathway	8.40e-02	1.00e+00	3.515	1	1	51
GO:0030900	forebrain development	8.40e-02	1.00e+00	3.515	1	1	51
GO:0003684	damaged DNA binding	8.40e-02	1.00e+00	3.515	1	2	51
GO:0045732	positive regulation of protein catabolic process	8.40e-02	1.00e+00	3.515	1	1	51
GO:0008202	steroid metabolic process	8.55e-02	1.00e+00	3.487	1	1	52
GO:0019899	enzyme binding	8.69e-02	1.00e+00	2.017	2	5	288
GO:0006952	defense response	8.71e-02	1.00e+00	3.459	1	1	53
GO:0030175	filopodium	8.71e-02	1.00e+00	3.459	1	2	53
GO:0007264	small GTPase mediated signal transduction	8.79e-02	1.00e+00	2.007	2	7	290
GO:0009612	response to mechanical stimulus	8.87e-02	1.00e+00	3.432	1	1	54
GO:0097193	intrinsic apoptotic signaling pathway	9.03e-02	1.00e+00	3.406	1	2	55
GO:0002039	p53 binding	9.03e-02	1.00e+00	3.406	1	1	55
GO:0046330	positive regulation of JNK cascade	9.03e-02	1.00e+00	3.406	1	1	55
GO:0043234	protein complex	9.31e-02	1.00e+00	1.958	2	9	300
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	9.34e-02	1.00e+00	3.354	1	1	57
GO:0005886	plasma membrane	9.85e-02	1.00e+00	0.718	8	24	2834
GO:0005794	Golgi apparatus	9.88e-02	1.00e+00	1.428	3	8	650
GO:0033138	positive regulation of peptidyl-serine phosphorylation	9.96e-02	1.00e+00	3.256	1	1	61
GO:0005739	mitochondrion	1.01e-01	1.00e+00	1.156	4	10	1046
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.01e-01	1.00e+00	3.233	1	1	62
GO:0000151	ubiquitin ligase complex	1.03e-01	1.00e+00	3.210	1	1	63
GO:0005901	caveola	1.03e-01	1.00e+00	3.210	1	1	63
GO:0019903	protein phosphatase binding	1.03e-01	1.00e+00	3.210	1	1	63
GO:0042995	cell projection	1.03e-01	1.00e+00	3.210	1	1	63
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.03e-01	1.00e+00	3.210	1	2	63
GO:0006417	regulation of translation	1.03e-01	1.00e+00	3.210	1	4	63
GO:0032869	cellular response to insulin stimulus	1.04e-01	1.00e+00	3.187	1	2	64
GO:0016491	oxidoreductase activity	1.06e-01	1.00e+00	3.165	1	1	65
GO:0071260	cellular response to mechanical stimulus	1.07e-01	1.00e+00	3.143	1	3	66
GO:0007411	axon guidance	1.08e-01	1.00e+00	1.834	2	3	327
GO:0030141	secretory granule	1.09e-01	1.00e+00	3.121	1	2	67
GO:0043231	intracellular membrane-bounded organelle	1.10e-01	1.00e+00	1.812	2	3	332
GO:0035264	multicellular organism growth	1.13e-01	1.00e+00	3.058	1	1	70
GO:0042393	histone binding	1.15e-01	1.00e+00	3.037	1	1	71
GO:0001503	ossification	1.15e-01	1.00e+00	3.037	1	2	71
GO:0043086	negative regulation of catalytic activity	1.20e-01	1.00e+00	2.978	1	1	74
GO:0042826	histone deacetylase binding	1.20e-01	1.00e+00	2.978	1	1	74
GO:0060070	canonical Wnt signaling pathway	1.21e-01	1.00e+00	2.958	1	2	75
GO:0007265	Ras protein signal transduction	1.21e-01	1.00e+00	2.958	1	3	75
GO:0051897	positive regulation of protein kinase B signaling	1.21e-01	1.00e+00	2.958	1	1	75
GO:0044325	ion channel binding	1.24e-01	1.00e+00	2.920	1	3	77
GO:0007229	integrin-mediated signaling pathway	1.26e-01	1.00e+00	2.902	1	2	78
GO:0071013	catalytic step 2 spliceosome	1.27e-01	1.00e+00	2.883	1	1	79
GO:0010629	negative regulation of gene expression	1.29e-01	1.00e+00	2.865	1	2	80
GO:0006351	transcription, DNA-templated	1.30e-01	1.00e+00	0.879	5	17	1585
GO:0050796	regulation of insulin secretion	1.32e-01	1.00e+00	2.830	1	1	82
GO:0045177	apical part of cell	1.32e-01	1.00e+00	2.830	1	1	82
GO:0004713	protein tyrosine kinase activity	1.32e-01	1.00e+00	2.830	1	1	82
GO:0030336	negative regulation of cell migration	1.33e-01	1.00e+00	2.812	1	2	83
GO:0005179	hormone activity	1.35e-01	1.00e+00	2.795	1	1	84
GO:0042593	glucose homeostasis	1.42e-01	1.00e+00	2.711	1	1	89
GO:0042384	cilium assembly	1.44e-01	1.00e+00	2.695	1	2	90
GO:0000922	spindle pole	1.45e-01	1.00e+00	2.679	1	5	91
GO:0016337	single organismal cell-cell adhesion	1.47e-01	1.00e+00	2.664	1	2	92
GO:0006928	cellular component movement	1.47e-01	1.00e+00	2.664	1	4	92
GO:0005200	structural constituent of cytoskeleton	1.48e-01	1.00e+00	2.648	1	6	93
GO:0005770	late endosome	1.49e-01	1.00e+00	2.632	1	1	94
GO:0030426	growth cone	1.54e-01	1.00e+00	2.587	1	3	97
GO:0000139	Golgi membrane	1.54e-01	1.00e+00	1.515	2	7	408
GO:0051015	actin filament binding	1.54e-01	1.00e+00	2.587	1	1	97
GO:0005178	integrin binding	1.54e-01	1.00e+00	2.587	1	1	97
GO:0006112	energy reserve metabolic process	1.57e-01	1.00e+00	2.558	1	2	99
GO:0014069	postsynaptic density	1.67e-01	1.00e+00	2.459	1	3	106
GO:0005096	GTPase activator activity	1.70e-01	1.00e+00	2.432	1	3	108
GO:0005815	microtubule organizing center	1.73e-01	1.00e+00	2.406	1	4	110
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1.73e-01	1.00e+00	2.406	1	1	110
GO:0020037	heme binding	1.74e-01	1.00e+00	2.393	1	1	111
GO:0050900	leukocyte migration	1.74e-01	1.00e+00	2.393	1	1	111
GO:0007596	blood coagulation	1.89e-01	1.00e+00	1.329	2	5	464
GO:0032496	response to lipopolysaccharide	1.90e-01	1.00e+00	2.256	1	1	122
GO:0051056	regulation of small GTPase mediated signal transduction	1.91e-01	1.00e+00	2.245	1	3	123
GO:0030036	actin cytoskeleton organization	1.99e-01	1.00e+00	2.176	1	3	129
GO:0046983	protein dimerization activity	2.02e-01	1.00e+00	2.154	1	3	131
GO:0045893	positive regulation of transcription, DNA-templated	2.03e-01	1.00e+00	1.259	2	8	487
GO:0018108	peptidyl-tyrosine phosphorylation	2.05e-01	1.00e+00	2.132	1	1	133
GO:0016055	Wnt signaling pathway	2.16e-01	1.00e+00	2.048	1	3	141
GO:0005911	cell-cell junction	2.17e-01	1.00e+00	2.037	1	2	142
GO:0008286	insulin receptor signaling pathway	2.20e-01	1.00e+00	2.017	1	4	144
GO:0055085	transmembrane transport	2.20e-01	1.00e+00	1.181	2	3	514
GO:0007165	signal transduction	2.21e-01	1.00e+00	0.880	3	7	950
GO:0046777	protein autophosphorylation	2.39e-01	1.00e+00	1.883	1	1	158
GO:0008022	protein C-terminus binding	2.43e-01	1.00e+00	1.856	1	4	161
GO:0005516	calmodulin binding	2.44e-01	1.00e+00	1.847	1	3	162
GO:0000398	mRNA splicing, via spliceosome	2.48e-01	1.00e+00	1.821	1	2	165
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2.52e-01	1.00e+00	1.795	1	4	168
GO:0030424	axon	2.57e-01	1.00e+00	1.761	1	4	172
GO:0016607	nuclear speck	2.61e-01	1.00e+00	1.736	1	2	175
GO:0004672	protein kinase activity	2.65e-01	1.00e+00	1.711	1	4	178
GO:0005764	lysosome	2.70e-01	1.00e+00	1.679	1	2	182
GO:0032403	protein complex binding	2.73e-01	1.00e+00	1.656	1	2	185
GO:0043547	positive regulation of GTPase activity	2.80e-01	1.00e+00	1.617	1	4	190
GO:0005654	nucleoplasm	2.89e-01	1.00e+00	0.675	3	26	1095
GO:0003924	GTPase activity	2.96e-01	1.00e+00	1.522	1	6	203
GO:0030168	platelet activation	2.98e-01	1.00e+00	1.508	1	4	205
GO:0004871	signal transducer activity	3.12e-01	1.00e+00	1.432	1	1	216
GO:0006184	GTP catabolic process	3.16e-01	1.00e+00	1.406	1	6	220
GO:0016874	ligase activity	3.21e-01	1.00e+00	1.380	1	2	224
GO:0030425	dendrite	3.40e-01	1.00e+00	1.280	1	3	240
GO:0004842	ubiquitin-protein transferase activity	3.58e-01	1.00e+00	1.187	1	3	256
GO:0005874	microtubule	3.60e-01	1.00e+00	1.176	1	3	258
GO:0005102	receptor binding	3.71e-01	1.00e+00	1.121	1	2	268
GO:0000166	nucleotide binding	3.76e-01	1.00e+00	1.100	1	2	272
GO:0007283	spermatogenesis	3.80e-01	1.00e+00	1.079	1	2	276
GO:0044281	small molecule metabolic process	3.85e-01	1.00e+00	0.433	3	16	1295
GO:0042493	response to drug	3.93e-01	1.00e+00	1.017	1	2	288
GO:0005743	mitochondrial inner membrane	4.05e-01	1.00e+00	0.958	1	1	300
GO:0005524	ATP binding	4.14e-01	1.00e+00	0.369	3	19	1354
GO:0004674	protein serine/threonine kinase activity	4.18e-01	1.00e+00	0.902	1	6	312
GO:0035556	intracellular signal transduction	4.23e-01	1.00e+00	0.879	1	5	317
GO:0005525	GTP binding	4.34e-01	1.00e+00	0.830	1	6	328
GO:0008283	cell proliferation	4.37e-01	1.00e+00	0.816	1	4	331
GO:0005813	centrosome	4.45e-01	1.00e+00	0.782	1	9	339
GO:0007275	multicellular organismal development	4.50e-01	1.00e+00	0.761	1	2	344
GO:0003723	RNA binding	4.60e-01	1.00e+00	0.715	1	10	355
GO:0030054	cell junction	4.61e-01	1.00e+00	0.711	1	4	356
GO:0008285	negative regulation of cell proliferation	4.71e-01	1.00e+00	0.667	1	3	367
GO:0045892	negative regulation of transcription, DNA-templated	5.22e-01	1.00e+00	0.459	1	2	424
GO:0006366	transcription from RNA polymerase II promoter	5.23e-01	1.00e+00	0.456	1	3	425
GO:0006468	protein phosphorylation	5.57e-01	1.00e+00	0.320	1	6	467
GO:0055114	oxidation-reduction process	5.68e-01	1.00e+00	0.277	1	2	481
GO:0006355	regulation of transcription, DNA-templated	5.74e-01	1.00e+00	0.079	2	10	1104
GO:0042802	identical protein binding	5.75e-01	1.00e+00	0.248	1	4	491
GO:0048471	perinuclear region of cytoplasm	5.99e-01	1.00e+00	0.156	1	9	523
GO:0005509	calcium ion binding	6.43e-01	1.00e+00	-0.015	1	4	589
GO:0005783	endoplasmic reticulum	6.56e-01	1.00e+00	-0.066	1	6	610
GO:0003700	sequence-specific DNA binding transcription factor activity	7.31e-01	1.00e+00	-0.360	1	9	748
GO:0005615	extracellular space	8.33e-01	1.00e+00	-0.793	1	3	1010
GO:0008270	zinc ion binding	8.50e-01	1.00e+00	-0.872	1	7	1067
GO:0003677	DNA binding	9.11e-01	1.00e+00	-1.213	1	14	1351
GO:0046872	metal ion binding	9.28e-01	1.00e+00	-1.330	1	14	1465

Tai-Luciferase

meta-reg-snw-10097

Interacting subnets

Genes (28)

Interactions (55)

Related GO terms (477)