reg-snw-10097

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.851	3.99e-26	2.69e-04	4.60e-04

tai-screen-luciferase-reg-snw-10097 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
[ ACTR2 ]	10097	1	-2.490	4.851	65	-	Yes	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
IQGAP1	8826	1	-3.777	4.851	10	TF	-	-
CUL4B	8450	6	-2.809	5.269	142	TF	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes
CDC5L	988	15	-3.419	5.672	155	TF	-	-

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CUL4B	8450	ACTR2	10097	pd	>	reg.ITFP.txt: no annot
CDC5L	988	ACTR2	10097	pd	>	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot
COPA	1314	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
IQGAP1	8826	ACTR2	10097	pd	>	reg.ITFP.txt: no annot
COPA	1314	ACTR2	10097	pd	>	reg.ITFP.txt: no annot

Related GO terms (110)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0071987	WD40-repeat domain binding	6.14e-04	1.00e+00	10.668	1	1	1
GO:0035305	negative regulation of dephosphorylation	6.14e-04	1.00e+00	10.668	1	1	1
GO:0015630	microtubule cytoskeleton	8.56e-04	1.00e+00	5.440	2	2	75
GO:0016344	meiotic chromosome movement towards spindle pole	1.23e-03	1.00e+00	9.668	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.23e-03	1.00e+00	9.668	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.23e-03	1.00e+00	9.668	1	1	2
GO:0033206	meiotic cytokinesis	1.23e-03	1.00e+00	9.668	1	1	2
GO:0008356	asymmetric cell division	1.84e-03	1.00e+00	9.083	1	1	3
GO:0051653	spindle localization	1.84e-03	1.00e+00	9.083	1	1	3
GO:0030478	actin cap	1.84e-03	1.00e+00	9.083	1	1	3
GO:0016482	cytoplasmic transport	1.84e-03	1.00e+00	9.083	1	1	3
GO:0050658	RNA transport	2.46e-03	1.00e+00	8.668	1	1	4
GO:0030157	pancreatic juice secretion	2.46e-03	1.00e+00	8.668	1	1	4
GO:1990138	neuron projection extension	2.46e-03	1.00e+00	8.668	1	1	4
GO:0015629	actin cytoskeleton	2.78e-03	1.00e+00	4.581	2	3	136
GO:0016020	membrane	2.83e-03	1.00e+00	2.431	4	25	1207
GO:0000974	Prp19 complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0072015	glomerular visceral epithelial cell development	3.07e-03	1.00e+00	8.347	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0000930	gamma-tubulin complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0070914	UV-damage excision repair	3.68e-03	1.00e+00	8.083	1	1	6
GO:0005885	Arp2/3 protein complex	4.29e-03	1.00e+00	7.861	1	1	7
GO:0036057	slit diaphragm	4.29e-03	1.00e+00	7.861	1	1	7
GO:0030126	COPI vesicle coat	4.29e-03	1.00e+00	7.861	1	1	7
GO:0035518	histone H2A monoubiquitination	4.29e-03	1.00e+00	7.861	1	1	7
GO:0005662	DNA replication factor A complex	4.91e-03	1.00e+00	7.668	1	1	8
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	4.91e-03	1.00e+00	7.668	1	1	8
GO:0034314	Arp2/3 complex-mediated actin nucleation	5.52e-03	1.00e+00	7.499	1	1	9
GO:0001817	regulation of cytokine production	5.52e-03	1.00e+00	7.499	1	1	9
GO:0005099	Ras GTPase activator activity	6.13e-03	1.00e+00	7.347	1	1	10
GO:0007051	spindle organization	6.13e-03	1.00e+00	7.347	1	1	10
GO:0005095	GTPase inhibitor activity	6.13e-03	1.00e+00	7.347	1	1	10
GO:0005737	cytoplasm	6.61e-03	1.00e+00	1.628	5	39	2633
GO:0051297	centrosome organization	7.35e-03	1.00e+00	7.083	1	1	12
GO:0048205	COPI coating of Golgi vesicle	7.35e-03	1.00e+00	7.083	1	1	12
GO:0043539	protein serine/threonine kinase activator activity	7.35e-03	1.00e+00	7.083	1	1	12
GO:0035371	microtubule plus-end	7.96e-03	1.00e+00	6.968	1	1	13
GO:0070062	extracellular vesicular exosome	8.95e-03	1.00e+00	1.988	4	28	1641
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	9.18e-03	1.00e+00	6.762	1	1	15
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.04e-02	1.00e+00	6.581	1	1	17
GO:0071364	cellular response to epidermal growth factor stimulus	1.10e-02	1.00e+00	6.499	1	1	18
GO:0032320	positive regulation of Ras GTPase activity	1.10e-02	1.00e+00	6.499	1	1	18
GO:0005925	focal adhesion	1.15e-02	1.00e+00	3.529	2	12	282
GO:0048365	Rac GTPase binding	1.16e-02	1.00e+00	6.421	1	1	19
GO:0036464	cytoplasmic ribonucleoprotein granule	1.16e-02	1.00e+00	6.421	1	4	19
GO:0007163	establishment or maintenance of cell polarity	1.22e-02	1.00e+00	6.347	1	2	20
GO:0071902	positive regulation of protein serine/threonine kinase activity	1.22e-02	1.00e+00	6.347	1	1	20
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1.28e-02	1.00e+00	6.276	1	1	21
GO:0031252	cell leading edge	1.47e-02	1.00e+00	6.083	1	2	24
GO:0071277	cellular response to calcium ion	1.59e-02	1.00e+00	5.968	1	1	26
GO:0005884	actin filament	1.65e-02	1.00e+00	5.914	1	1	27
GO:0016328	lateral plasma membrane	1.89e-02	1.00e+00	5.714	1	2	31
GO:0045732	positive regulation of protein catabolic process	2.07e-02	1.00e+00	5.581	1	1	34
GO:0045860	positive regulation of protein kinase activity	2.25e-02	1.00e+00	5.459	1	1	37
GO:0042995	cell projection	2.49e-02	1.00e+00	5.311	1	1	41
GO:0003684	damaged DNA binding	2.49e-02	1.00e+00	5.311	1	1	41
GO:0043086	negative regulation of catalytic activity	2.73e-02	1.00e+00	5.177	1	1	45
GO:0019903	protein phosphatase binding	2.85e-02	1.00e+00	5.114	1	1	47
GO:0005730	nucleolus	2.89e-02	1.00e+00	2.004	3	21	1217
GO:0042384	cilium assembly	3.21e-02	1.00e+00	4.941	1	1	53
GO:0050796	regulation of insulin secretion	3.27e-02	1.00e+00	4.914	1	1	54
GO:0005179	hormone activity	3.63e-02	1.00e+00	4.762	1	1	60
GO:0071013	catalytic step 2 spliceosome	3.69e-02	1.00e+00	4.738	1	1	61
GO:0051015	actin filament binding	3.81e-02	1.00e+00	4.691	1	1	63
GO:0030426	growth cone	3.87e-02	1.00e+00	4.668	1	3	64
GO:0006112	energy reserve metabolic process	3.93e-02	1.00e+00	4.646	1	2	65
GO:0000922	spindle pole	4.11e-02	1.00e+00	4.581	1	3	68
GO:0005096	GTPase activator activity	4.11e-02	1.00e+00	4.581	1	3	68
GO:0005200	structural constituent of cytoskeleton	4.11e-02	1.00e+00	4.581	1	4	68
GO:0006928	cellular component movement	4.23e-02	1.00e+00	4.539	1	3	70
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	4.23e-02	1.00e+00	4.539	1	3	70
GO:0030496	midbody	4.40e-02	1.00e+00	4.479	1	3	73
GO:0006886	intracellular protein transport	5.35e-02	1.00e+00	4.193	1	1	89
GO:0061024	membrane organization	5.35e-02	1.00e+00	4.193	1	3	89
GO:0006511	ubiquitin-dependent protein catabolic process	5.52e-02	1.00e+00	4.145	1	1	92
GO:0000086	G2/M transition of mitotic cell cycle	5.82e-02	1.00e+00	4.069	1	3	97
GO:0005516	calmodulin binding	5.93e-02	1.00e+00	4.039	1	2	99
GO:0005198	structural molecule activity	6.05e-02	1.00e+00	4.010	1	1	101
GO:0043547	positive regulation of GTPase activity	6.69e-02	1.00e+00	3.861	1	4	112
GO:0043005	neuron projection	6.75e-02	1.00e+00	3.848	1	2	113
GO:0007049	cell cycle	6.86e-02	1.00e+00	3.823	1	2	115
GO:0016607	nuclear speck	7.27e-02	1.00e+00	3.738	1	2	122
GO:0030424	axon	7.61e-02	1.00e+00	3.668	1	4	128
GO:0000398	mRNA splicing, via spliceosome	7.61e-02	1.00e+00	3.668	1	2	128
GO:0032403	protein complex binding	7.73e-02	1.00e+00	3.646	1	2	130
GO:0005829	cytosol	7.91e-02	1.00e+00	1.450	3	33	1787
GO:0031625	ubiquitin protein ligase binding	8.19e-02	1.00e+00	3.560	1	2	138
GO:0007173	epidermal growth factor receptor signaling pathway	8.42e-02	1.00e+00	3.519	1	3	142
GO:0005874	microtubule	9.61e-02	1.00e+00	3.320	1	2	163
GO:0007067	mitotic nuclear division	9.72e-02	1.00e+00	3.302	1	5	165
GO:0007264	small GTPase mediated signal transduction	1.02e-01	1.00e+00	3.225	1	4	174
GO:0043234	protein complex	1.22e-01	1.00e+00	2.954	1	8	210
GO:0005813	centrosome	1.26e-01	1.00e+00	2.907	1	6	217
GO:0030054	cell junction	1.27e-01	1.00e+00	2.900	1	3	218
GO:0019901	protein kinase binding	1.34e-01	1.00e+00	2.810	1	8	232
GO:0003682	chromatin binding	1.45e-01	1.00e+00	2.691	1	3	252
GO:0000278	mitotic cell cycle	1.78e-01	1.00e+00	2.374	1	9	314
GO:0005509	calcium ion binding	1.97e-01	1.00e+00	2.213	1	3	351
GO:0005515	protein binding	2.11e-01	1.00e+00	0.659	4	50	4124
GO:0045087	innate immune response	2.48e-01	1.00e+00	1.848	1	6	452
GO:0005886	plasma membrane	3.02e-01	1.00e+00	0.868	2	13	1784
GO:0005634	nucleus	3.18e-01	1.00e+00	0.589	3	40	3246
GO:0007165	signal transduction	3.25e-01	1.00e+00	1.397	1	5	618
GO:0005615	extracellular space	3.39e-01	1.00e+00	1.322	1	2	651
GO:0006355	regulation of transcription, DNA-templated	3.66e-01	1.00e+00	1.187	1	9	715
GO:0044822	poly(A) RNA binding	4.01e-01	1.00e+00	1.026	1	25	799
GO:0044281	small molecule metabolic process	4.19e-01	1.00e+00	0.947	1	8	844
GO:0005524	ATP binding	4.37e-01	1.00e+00	0.868	1	10	892
GO:0003677	DNA binding	4.58e-01	1.00e+00	0.781	1	12	947
GO:0006351	transcription, DNA-templated	5.04e-01	1.00e+00	0.597	1	15	1076

Tai-Luciferase

reg-snw-10097

Statistics

Genes (6)

Interactions (8)

Related GO terms (110)